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A narrative review of coronavirus disease 2019 (COVID-19): clinical, epidemiological ch...
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Internal and Emergency Medicine; Krishnan A, Hamilton JP et. al.

Jan 16th, 2021 - Coronavirus disease 2019 (COVID-19) is an emerging infectious disease which has had a rapid surge in cases and deaths since it is first documented in Wuhan, China, in December 2019. COVID-19 is caused by the Betacoronavirus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). SARS-CoV-2 uses angiotensin-converting enzyme 2, which is highly expressed in the human lower respiratory tract...

Socioeconomic status and cardiovascular health in the COVID-19 pandemic.
https://doi.org/10.1136/heartjnl-2020-318425
Heart (British Cardiac Society); Naylor-Wardle J, Rowland B et. al.

Jan 16th, 2021 - The goals of this review are to evaluate the impact of socioeconomic (SE) status on the general health and cardiovascular health of individuals during the COVID-19 pandemic and also discuss the measures to address disparity. SE status is a strong predictor of premature morbidity and mortality within general health. A lower SE status also has implications of increased cardiovascular disease (CVD...

Association of ABO blood group type with cardiovascular events in COVID-19.
https://doi.org/10.1007/s11239-020-02364-5 10.1016/j.jacc.2020.08.070 10.1056/NEJMoa2020283 10.1007/s00277-020-04169-1 10.1371/journal.ppat.1008556 10.1093/glycob/cwn093 10.1161/CIRCULATIONAHA.115.017563
Journal of Thrombosis and Thrombolysis; Nauffal V, Achanta A et. al.

Jan 16th, 2021 - Cardiovascular complications have been reported in patients with COVID-19. We sought to examine the association of ABO blood group type with cardiovascular complications in COVID-19. We examined 409 individuals enrolled in the COVID-19 Registry to Assess Frequency, Management, and Outcomes of Arterial and Venous Thromboembolic Complications (CORONA-VTE) who had ABO blood group data available. M...

Different characteristics of critical COVID-19 and thinking of treatment strategies in ...
https://doi.org/10.1016/j.intimp.2020.107343
International Immunopharmacology; Liu Z, Wu D et. al.

Jan 15th, 2021 - The differences in the characteristics and main causes of critical COVID-19 infection in non-elderly and elderly severe patients remain unknown. We included 273 adult patients with confirmed severe COVID-19 from Tongji Hospital, Wuhan, China from February 10 to March 8, 2020. Clinical characteristics and risk factors for outcomes were compared between the young and middle-aged and the elderly s...

Cardiovascular Deaths During the COVID-19 Pandemic in the United States.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7800141
Journal of the American College of Cardiology; Wadhera RK, Shen C et. al.

Jan 15th, 2021 - Although the direct toll of COVID-19 in the United States has been substantial, concerns have also arisen about the indirect effects of the pandemic. Hospitalizations for acute cardiovascular conditions have declined, raising concern that patients may be avoiding hospitals because of fear of contracting severe acute respiratory syndrome- coronavirus-2 (SARS-CoV-2). Other factors, including stra...

COVID-19 and Cardiovascular Health: This Is a Public Service Announcement.
https://doi.org/10.1016/j.jacc.2020.11.027
Journal of the American College of Cardiology; Young MN, Iribarne A et. al.

Jan 15th, 2021 - COVID-19 and Cardiovascular Health: This Is a Public Service Announcement.|2021|Young MN,Iribarne A,Malenka D,|

International Impact of COVID-19 on the Diagnosis of Heart Disease.
https://doi.org/10.1016/j.jacc.2020.10.054
Journal of the American College of Cardiology; Einstein AJ, Shaw LJ et. al.

Jan 15th, 2021 - The coronavirus disease 2019 (COVID-19) pandemic has adversely affected diagnosis and treatment of noncommunicable diseases. Its effects on delivery of diagnostic care for cardiovascular disease, which remains the leading cause of death worldwide, have not been quantified. The study sought to assess COVID-19's impact on global cardiovascular diagnostic procedural volumes and safety practices. T...

Effects of Life Events and Social Isolation on Stroke and Coronary Heart Disease.
https://doi.org/10.1161/STROKEAHA.120.032070
Stroke Gronewold J, Engels M et. al.

Jan 15th, 2021 - The current coronavirus disease 2019 (COVID-19) pandemic represents a severe, life-changing event for people across the world. Life changes may involve job loss, income reduction due to furlough, death of a beloved one, or social stress due to life habit changes. Many people suffer from social isolation due to lockdown or physical distancing, especially those living alone and without family. Th...

Mechanical circulatory support-Challenges, strategies, and preparations.
https://doi.org/10.1111/jocs.15301
Journal of Cardiac Surgery REFERENCES; Awad WI, Bashir M

Jan 14th, 2021 - Coronavirus disease 2019 (COVID-19) is usually mild, but patients can present with pneumonia, acute respiratory distress syndrome (ARDS), and circulatory shock. Although the symptoms of the disease are predominantly respiratory, the involvement of the cardiovascular system is common. Patients with heart failure (HF) are particularly vulnerable when suffering from COVID-19. To examine the challe...

Heartbeat: an increase in preventable cardiovascular deaths during the COVID-19 pandemi...
https://doi.org/10.1136/heartjnl-2020-318759
Heart (British Cardiac Society); Otto CM

Jan 14th, 2021 - Heartbeat: an increase in preventable cardiovascular deaths during the COVID-19 pandemic due to avoidance of medical care.|2021|Otto CM,|

An early experience on the effect of solid organ transplant status on hospitalized COVI...
https://doi.org/10.1111/ajt.16460
American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons REFERENCES; Nair V, Jandovitz N et. al.

Jan 14th, 2021 - We compared the outcome of COVID-19 in immunosuppressed solid organ transplant (SOT) patients to a transplant naïve population. In total, 10 356 adult hospital admissions for COVID-19 from March 1, 2020 to April 27, 2020 were analyzed. Data were collected on demographics, baseline clinical conditions, medications, immunosuppression, and COVID-19 course. Primary outcome was combined death or mec...

Adverse effects of non-steroidal anti-inflammatory drugs in patients with viral respira...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7678345
BMJ Open; von Philipsborn P, Biallas R et. al.

Jan 14th, 2021 - To assess the effects of non-steroidal anti-inflammatory drugs (NSAIDs) in patients with viral respiratory infections on acute severe adverse outcomes, healthcare utilisation, quality of life and long-term survival. Rapid systematic review. Humans with viral respiratory infections, exposed to systemic NSAIDs. Acute severe adverse outcomes, healthcare utilisation, quality of life and long-term s...

Cardiac Surgery Outcomes in an Epicenter of the COVID-19 Pandemic.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7801821
Seminars in Thoracic and Cardiovascular Surgery; Farrington WJ, Robinson NB et. al.

Jan 14th, 2021 - As New York State quickly became the epicenter of the COVID-19 pandemic, innovative strategies to provide care for the COVID-19 negative patients with urgent or immediately life threatening cardiovascular conditions became imperative. To date, there has not been a focused analysis of patients undergoing cardiothoracic surgery in the United States during the COVID-19 pandemic. Therefore, we seek...

Study protocol for COVID-RV: a multicentre prospective observational cohort study of ri...
https://doi.org/10.1136/bmjopen-2020-042098
BMJ Open; Willder JM, McCall P et. al.

Jan 14th, 2021 - COVID-19 can cause severe acute respiratory failure requiring management in intensive care unit with invasive ventilation and a 40% mortality rate. Cardiovascular manifestations are common and studies have shown an increase in right ventricular (RV) dysfunction associated with mortality. These studies, however, comprise heterogeneous patient groups with few requiring invasive ventilation. This ...

Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2): a Systemic Infection.
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Clinical Microbiology Reviews; Synowiec A, Szczepański A et. al.

Jan 14th, 2021 - To date, seven identified coronaviruses (CoVs) have been found to infect humans; of these, three highly pathogenic variants have emerged in the 21st century. The newest member of this group, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), was first detected at the end of 2019 in Hubei province, China. Since then, this novel coronavirus has spread worldwide, causing a pandemic; the...

FDA Welcomes Sotagliflozin Data for Heart Failure in Diabetes
https://www.medscape.com/viewarticle/944207

Jan 14th, 2021 - The Food and Drug Administration has determined that data collected on the dual SGLT1/2 inhibitor sotagliflozin (Zynquista) for treating patients with type 2 diabetes in the SOLOIST and SCORED pivotal trials can help support a New Drug Application (NDA) submission, according to a statement released on Jan. 14 by Lexicon Pharmaceuticals, the company developing this drug. Lexicon concurrently sai...

Point-of-Care Echocardiography and Hemodynamic Monitoring in Cirrhosis and Acute-on-Chr...
https://doi.org/10.1177/0885066620988281
Journal of Intensive Care Medicine; Premkumar M, Kajal K et. al.

Jan 13th, 2021 - Point-of-Care (POC) transthoracic echocardiography (TTE) is transforming the management of patients with cirrhosis presenting with septic shock, acute kidney injury, hepatorenal syndrome and acute-on-chronic liver failure (ACLF) by correctly assessing the hemodynamic and volume status at the bedside using combined echocardiography and POC ultrasound (POCUS). When POC TTE is performed by the hep...

Efficacy and Cardiovascular Safety of Antidiabetic Medications.
https://doi.org/10.2174/1574886316666210112153429
Current Drug Safety; Pappachan JM

Jan 13th, 2021 - Diabetes mellitus (DM) has already affected one in every eleven person in the global population, and the disease prevalence continues to increase because of the obesity pandemic. Even with the availability of a multitude of antidiabetic medications for optimal glycaemic control, cardiovascular morbidity and mortality were not largely altered until recently when newer antidiabetic drugs such as ...

Benefits behind barriers in physiology education.
https://doi.org/10.1152/advan.00189.2020
Advances in Physiology Education; Gopalan C

Jan 13th, 2021 - The COVID-19 pandemic forced academics to switch to online teaching whether they were prepared or not. The speed and enthusiasm with which educators embraced online teaching suggest that challenges change the perspective for the better. The teaching challenges with the current coronavirus situation mimic the poliovirus attack Dr. Arthur C. Guyton encountered. Dr. Guyton was forced to switch his...

Arthritis Drugs 'Impressive' for Severe COVID but Not 'Magic Cure'
https://www.medscape.com/viewarticle/944092

Jan 13th, 2021 - Editor's note: Find the latest COVID-19 news and guidance in Medscape's Coronavirus Resource Center. New findings suggest that monoclonal antibodies used to treat rheumatoid arthritis could improve severe COVID-19 outcomes, including risk for death. Given within 24 hours of critical illness, tocilizumab (Actemra, Roche) was associated with a median of 10 days free of respiratory and cardiovascu...