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D-dimer surge and coagulation disorders in COVID-19 related pneumonia patients with car...
https://doi.org/10.1097/MD.0000000000021513
Medicine Wang X, Du B et. al.

Aug 5th, 2020 - Cardiac injury and coagulation disorders have been two increasing concerns in the management of patients with severe coronavirus disease (COVID-19). Coagulation disorders in COVID-19 patients with cardiac injury have not been characterized. We analyzed the data of five COVID-19 patients with cardiac injury who had D-dimer surge (defined as a rapid increase in the D-dimer level in 72 h, from <5-...

Cardiovascular Health in the COVID-19 Era: A Call for Action and Education.
https://doi.org/10.1016/j.mayocp.2020.05.031
Mayo Clinic Proceedings; Vallabhajosyula S, Friedman PA et. al.

Aug 5th, 2020 - Cardiovascular Health in the COVID-19 Era: A Call for Action and Education.|2020|Vallabhajosyula S,Friedman PA,Bell MR,|

Endothelial dysfunction in COVID-19: a position paper of the ESC Working Group for Athe...
https://doi.org/10.1093/cvr/cvaa230
Cardiovascular Research; Evans PC, Ed Rainger G et. al.

Aug 4th, 2020 - The COVID-19 pandemic is an unprecedented healthcare emergency causing mortality and illness across the world. Although primarily affecting the lungs, the SARS-CoV-2 virus also affects the cardiovascular system. In addition to cardiac effects, e.g. myocarditis, arrhythmias, and myocardial damage, the vasculature is affected in COVID-19, both directly by the SARS-CoV-2 virus, and indirectly as a...

Suppressed anti-inflammatory heat shock response in high-risk COVID-19 patients: lesson...
https://doi.org/10.1042/CS20200596
Clinical Science (London, England : 1979); Heck TG, Ludwig MS et. al.

Aug 4th, 2020 - The major risk factors to fatal outcome in COVID-19 patients, i.e., elderliness and pre-existing metabolic and cardiovascular diseases (CVD), share in common the characteristic of being chronic degenerative diseases of inflammatory nature associated with defective heat shock response (HSR). The molecular components of the HSR, the principal metabolic pathway leading to the physiological resolut...

A cytokine super cyclone in COVID-19 patients with risk factors: the therapeutic potent...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7328575
Cytokine & Growth Factor Reviews; Johnson BS, Laloraya M

Aug 4th, 2020 - The seventh human coronavirus SARS-CoV2 belongs to the cluster of extremely pathogenic coronaviruses including SARS-CoV and MERS-CoV, which can cause fatal lower respiratory tract infection. Likewise, SARS-CoV2 infection can be fatal as the disease advances to pneumonia, followed by acute respiratory distress syndrome (ARDS). The development of lethal clinical symptons is associated with an exa...

Biventricular strain by speckle tracking echocardiography in COVID-19: findings and pos...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7405100
Future Cardiology; Krishnamoorthy P, Croft LB et. al.

Aug 4th, 2020 - The COVID-19 infection adversely affects the cardiovascular system. Transthoracic echocardiography has demonstrated diagnostic, prognostic and therapeutic utility. We report biventricular myocardial strain in COVID-19. Methods: Biventricular strain measurements were performed for 12 patients. Patients who were discharged were compared with those who needed intubation and/or died. Results: Seven...

Decline of emergency admissions for cardiovascular and cerebrovascular events after the...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7399595
Clinical Research in Cardiology : Official Journal of the German Cardiac Society; Schwarz V, Mahfoud F et. al.

Aug 4th, 2020 - The spread of the novel coronavirus SARS-CoV-2 and the guidance from authorities for social distancing and media reporting lead to significant uncertainty in Germany. Concerns have been expressed regarding the underdiagnosing of harmful diseases. We explored the rates of emergency presentations for acute coronary syndrome (ACS) and acute cerebrovascular events (ACVE) before and after spread of ...

Temporal trends in the presentation of cardiovascular and cerebrovascular emergencies d...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7402080
Clinical Research in Cardiology : Official Journal of the German Cardiac Society; Seiffert M, Brunner FJ et. al.

Aug 4th, 2020 - The first reports of declining hospital admissions for major cardiovascular emergencies during the COVID-19 pandemic attracted public attention. However, systematic evidence on this subject is sparse. We aimed to investigate the rate of emergent hospital admissions, subsequent invasive treatments and comorbidities during the COVID-19 pandemic in Germany. This was a retrospective analysis of hea...

The potential role of the Carotid Body in COVID-19.
https://doi.org/10.1152/ajplung.00309.2020
American Journal of Physiology. Lung Cellular and Molecular Physiology; Porzionato A, Emmi A et. al.

Aug 4th, 2020 - The carotid body (CB) plays a contributory role in the pathogenesis of various respiratory, cardiovascular, renal and metabolic diseases, through reflex changes in ventilation and sympathetic output. On the basis of available data about peripheral arterial chemoreception and Severe Acute Respiratory Syndrome - Coronavirus 2 (SARS-CoV2), a potential involvement in the Coronavirus Disease 2019 (C...

Incorporating Health Equity and Community Perspectives During COVID-19: Commonalities w...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7360187
Ethnicity & Disease; Payton Foh E, Echeverria SE

Aug 3rd, 2020 - The COVID-19 pandemic is revealing the deeply entrenched structural inequities in health that exist in the United States. We draw parallels between the COVID-19 pandemic and our cardiovascular health equity research focused on physical activity and diabetes to highlight three common needs: 1) access to timely and disaggregated data; 2) how to integrate community-engaged approaches in telehealth...

COVID-19 and diabetes mellitus: how one pandemic worsens the other.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7395898
Reviews in Endocrine & Metabolic Disorders; Azar WS, Njeim R et. al.

Aug 3rd, 2020 - In light of the most challenging public health crisis of modern history, COVID-19 mortality continues to rise at an alarming rate. Patients with co-morbidities such as hypertension, cardiovascular disease, and diabetes mellitus (DM) seem to be more prone to severe symptoms and appear to have a higher mortality rate. In this review, we elucidate suggested mechanisms underlying the increased susc...

Mechanical circulatory support for cardiovascular complications in a young COVID-19 pat...
https://doi.org/10.1111/jocs.14916
Journal of Cardiac Surgery REFERENCES; Popov AF, Berger R et. al.

Aug 2nd, 2020 - The current coronavirus (COVID-19) pandemic is associated with severe pulmonary and cardiovascular complications. This report describes a young patient with COVID-19 without any comorbidity presenting with severe cardiovascular complications, manifesting with pulmonary embolism, embolic stroke, and right heart failure. Management with short-term mechanical circulatory support, including differe...

Long-term effects of COVID-19 in a patient on maintenance dialysis.
https://doi.org/10.1111/hdi.12859
Hemodialysis International. International Symposium on Home Hemodialysis REFERENCES; Alfano G, Perrone R et. al.

Aug 1st, 2020 - Coronavirus infectious disease (COVID-19) is a novel respiratory infection highly associated with severe complications in elderly subjects affected by cardiovascular disease. Patients on maintenance dialysis are exceptionally vulnerable because most of them are old and have multiple comorbidities. We report the complex clinical course of SARS-CoV-2 infection in a patient on maintenance dialysis...

Guidelines for balancing priorities in structural heart disease during the COVID-19 pan...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7261108
Cardiovascular Revascularization Medicine : Including Molecular Interventions; Khan JM, Khalid N et. al.

Aug 1st, 2020 - During the novel coronavirus disease 2019 (COVID-19) pandemic, many hospitals have been asked to postpone elective and surgical cases. This begs the question, "What is elective in structural heart disease intervention?" The recently proposed Society for Cardiovascular Angiography and Interventions/American College of Cardiology consensus statement is, unfortunately, non-specific and insufficien...

Hypertension and related diseases in the era of COVID-19: a report from the Japanese So...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7393334
Hypertension Research : Official Journal of the Japanese Society of Hypertension; Shibata S, Arima H et. al.

Aug 1st, 2020 - Coronavirus disease-2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has affected more than seven million people worldwide, contributing to 0.4 million deaths as of June 2020. The fact that the virus uses angiotensin-converting enzyme (ACE)-2 as the cell entry receptor and that hypertension as well as cardiovascular disorders frequently coexist with COVID...

Trauma of Major Surgery: A Global Problem that is Not Going Away.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7388795
International Journal of Surgery (London, England); Dobson GP

Aug 1st, 2020 - Globally, a staggering 310 million major surgeries are performed each year; around 40 to 50 million in USA and 20 million in Europe. It is estimated that 1 to 4% of these patients will die, up to 15% will have serious postoperative morbidity, and 5 to 15% will be readmitted within 30 days. An annual global mortality of around 8 million patients places major surgery comparable with the leading c...

The relationship between severe acute respiratory syndrome coronavirus 2 (SARS - COV - ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7375271
Journal of Electrocardiology; Bektaş O, Çerik İB et. al.

Jul 31st, 2020 - The aim of the study is to determine the frequency of fragmented QRS (FQRS) in patients with SARS - COV - 2. A total of 125 consecutive patients over 20 years of age who were hospitalized for SARS - COV - 2 between 20th March 2020 and 18th May 2020 were included in the study. The data of the patients in the inpatient ward and in the intensive care unit were recorded separately. The duration of ...

The characteristics and outcomes of 681 severe cases with COVID-19 in China.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7340593
Journal of Critical Care; Chen FF, Zhong M et. al.

Jul 31st, 2020 - To clarify the epidemiological, clinical, and therapeutic features of patients with severe COVID-19. In this study, we enrolled 681 patients with confirmed cases of severe COVID-19. The epidemiological, demographic, clinical, laboratory, treatment, and outcome data were collected. The median age of the study participants was 65 years, 53.2% were male, and 104 (15.3%) died. Age, Neutrophil-To-Ly...

The relationship between coronary artery disease and clinical outcomes in COVID-19: a s...
https://doi.org/10.1097/MCA.0000000000000934
Coronary Artery Disease; Peterson E, Lo KB et. al.

Jul 31st, 2020 - Recent studies have reported evidence that coronavirus disease 2019 (COVID-19) has disproportionately affected patients with underlying comorbidities. Our study aims to evaluate the impact of both cardiac and noncardiac comorbidities on a high-risk population with COVID-19 infection and coronary artery disease (CAD) compared to those without CAD. This is a retrospective study of patients who te...

Concerns for management of STEMI patients in the COVID-19 era: a paradox phenomenon.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7391023
Journal of Thrombosis and Thrombolysis; Vlachakis PK, Tentolouris A et. al.

Jul 31st, 2020 - The pandemic of coronavirus disease 2019 (COVID-19) has become a public health emergency of international concern. During this time, the management of people with acute coronary syndromes (ACS) and COVID-19 has become a global issue, especially since preexisting cardiovascular disease is a risk factor for the presence and the severity of COVID-19. The number of people with ST- elevation myocard...