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A public health approach to estimating the need for long COVID services.
https://doi.org/10.1093/pubmed/fdab365
Journal of Public Health (Oxford, England); Pye A, Roberts SR et. al.

Oct 16th, 2021 - The term 'long COVID' describes ongoing symptoms and conditions experienced by people infected with SARS-CoV-2. This paper illustrates how a public health approach was used to influence and inform the development of post-COVID services across two Integrated Care Systems (ICSs). A literature review was conducted between October and December 2020 to identify prevalence estimates for long COVID. T...

Safety of surgical masks during phisical activity evaluated with graded cycle ergometry...
https://doi.org/10.23736/S0022-4707.21.12814-2
The Journal of Sports Medicine and Physical Fitness; Pasqualetto MC, Tuttolomondo D et. al.

Oct 16th, 2021 - At the time of the coronavirus disease 2019 (COVID-19) pandemic wearing surgical mask (SM) is recommended for the prevention of contracting or exposing others to airborne transmission of COVID-19. It is somewhat controversial whether wearing SM during exercise affects performance and health status and/or may influence the results. In order to give an answer we planned a prospective, randomized,...

Avoidance of ST-Segment-Elevation Myocardial Infarction Treatment for >1 Week Due to CO...
https://doi.org/10.14503/THIJ-20-7390
Texas Heart Institute Journal; Annabathula RV, Sinner GJ et. al.

Oct 16th, 2021 - During the coronavirus disease 2019 (COVID-19) pandemic, social distancing guidelines have negatively affected the care-seeking behavior of patients with chronic medical conditions, including those with cardiovascular disease. We report the case of a 60-year-old man with vague gastrointestinal symptoms who waited more than 1 week to seek treatment for fear of COVID-19 infection. On presentation...

Clonal hematopoiesis is associated with risk of severe Covid-19.
https://doi.org/10.1038/s41467-021-26138-6 10.1161/CIRCULATIONAHA.119.044362 10.1016/j.jacc.2017.12.037 10.1016/j.stem.2018.10.013 10.1182/blood-2017-02-769869 10.1038/s41586-018-0321-x 10.1038/s41586-020-2426-2 10.1016/j.stemcr.2020.02.011 10.1056/NEJMoa1701719 10.1038/s41586-018-0125-z 10.1016/j.canlet.2019.09.013 10.1200/JCO.20.01307 10.1056/NEJMoa2002032 10.1001/jama.2020.4344 10.3346/jkms.2020.35.e280 10.1038/s41588-020-00710-0 10.1016/S0140-6736(20)31187-9 10.1200/JCO.20.01580 10.1016/j.ijid.2020.03.017 10.1097/HS9.0000000000000453 10.1038/s41591-021-01371-0 10.1186/s12885-019-6044-z
Nature Communications; Bolton KL, Koh Y et. al.

Oct 15th, 2021 - Acquired somatic mutations in hematopoietic stem and progenitor cells (clonal hematopoiesis or CH) are associated with advanced age, increased risk of cardiovascular and malignant diseases, and decreased overall survival. These adverse sequelae may be mediated by altered inflammatory profiles observed in patients with CH. A pro-inflammatory immunologic profile is also associated with worse outc...

A novel remote TSST procedure reliably increases stress reactivity in cannabis users: A...
https://doi.org/10.1037/pha0000528
Experimental and Clinical Psychopharmacology; Reed SC, Oliva A et. al.

Oct 15th, 2021 - The Trier Social Stress Test (TSST) is a standard laboratory stressor comprised of a speech and arithmetic tasks that reliably induces physiological and psychological stress. It is traditionally administered in a room where the participant takes part in the TSST in front of two "committee" members. However, due to the recent Coronavirus disease (COVID-19) pandemic, in-person research study proc...

Presence and clinical impact of human Herpesvirus-6 infection in patients with moderate...
https://doi.org/10.1002/jmv.27392
Journal of Medical Virology; Lino K, Alves LS et. al.

Oct 15th, 2021 - Human herpesvirus-6 (HHV-6) may cause serious diseases in immunocompromised individuals. SARS-CoV-2/HHV-6 co-infection has been emphasized in previous works, mostly case reports, small series or epidemiological studies, but few is known about its real clinical outcomes. Here we present a real-world pilot study aiming to understand the frequency and the clinical impact of HHV-6 co-infection in m...

CPR on a COVID Patient: Not a Moment to Waste Looking for PPE
https://www.medpagetoday.com/emergencymedicine/emergencymedicine/95038

Oct 14th, 2021 - Timely CPR on cardiac arrest patients with known or suspected COVID-19 should take precedence over resuscitators donning personal protective equipment (PPE), the American Heart Association (AHA) outlined in a guidance update. In resuscitation of adults and children, the healthcare provider is now instructed to give rapid chest compressions and to defibrillate as soon as possible without delay f...

Colchicine - From rheumatology to the new kid on the block: Coronary syndromes and COVI...
https://doi.org/10.5603/CJ.a2021.0123
Cardiology Journal; Surma S, Basiak M et. al.

Oct 14th, 2021 - Colchicine is an effective anti-inflammatory agent used to treat gout, coronary artery disease, viral pericarditis, and familial Mediterranean fever. It has been found to act by preventing the polymerization of the protein called tubulin, thus inhibiting inflammasome activation, proinflammatory chemokines, and cellular adhesion molecules. Accumulating evidence suggests that some patients with c...

Potential Cardiotoxic Effects of Remdesivir on Cardiovascular System: A Literature Review.
https://doi.org/10.1007/s12012-021-09703-9 10.1016/j.amjcard.2020.04.054 10.1016/j.antiviral.2020.104955 10.1111/cts.12882 10.1007/s10157-020-01996-4 10.22270/jddt.v10i4-s.4313 10.1056/NEJMoa2007016 10.1007/s40264-020-00952-1 10.1056/NEJMoa1910993 10.1016/S0140-6736(20)31022-9 10.1002/jmv.27177 10.1016/S0002-9149(01)01604-6 10.3390/ph14070611 10.1007/s00431-021-03940-4 10.1093/ehjcr/ytab200 10.3390/jcdd8020018 10.1093/jpids/piab029 10.1023/A:1009810025584
Cardiovascular Toxicology; Nabati M, Parsaee H

Oct 14th, 2021 - Corona disease 2019 (COVID-19) pandemic continues to spread around the world with no efficacious treatment. Intravenous remdesivir is the only authorized drug for treatment of COVID-19 disease under an Emergency Use Authorization. Remdesivir is a 1'-cyano-substituted adenosine nucleotide prodrug which inhibits viral RNA synthesis. This metabolite is an adenosine analog but with a significantly ...

Half of COVID Survivors Report Effects Beyond 6 Months: Review
https://www.medscape.com/viewarticle/960890

Oct 14th, 2021 - Editor's note: Find the latest COVID-19 news and guidance in Medscape's Coronavirus Resource Center. More than half of patients with persistent postacute sequelae of COVID-19 (PASC or long COVID) reported experiencing effects longer than 6 months after recovery, according to a systematic review of 57 studies that included more than 250,000 patients. The results indicate that long COVID is commo...

Assessing Performance of the Veterans Affairs Women Cardiovascular Risk Model in Predic...
https://doi.org/10.3390/ijerph181910005
International Journal of Environmental Research and Publi... Jeon-Slaughter H, Chen X et. al.

Oct 14th, 2021 - The current study assessed performance of the new Veterans Affairs (VA) women cardiovascular disease (CVD) risk score in predicting women veterans' 60-day CVD event risk using VA COVID-19 shared cohort data. The study data included 17,264 women veterans-9658 White, 6088 African American, and 1518 Hispanic women veterans-ever treated at US VA hospitals and clinics between 24 February and 25 Nove...

Short-term and Long-term Rates of Postacute Sequelae of SARS-CoV-2 Infection: A Systema...
https://doi.org/10.1001/jamanetworkopen.2021.28568
JAMA Network Open; Groff D, Sun A et. al.

Oct 14th, 2021 - Short-term and long-term persistent postacute sequelae of COVID-19 (PASC) have not been systematically evaluated. The incidence and evolution of PASC are dependent on time from infection, organ systems and tissue affected, vaccination status, variant of the virus, and geographic region. To estimate organ system-specific frequency and evolution of PASC. PubMed (MEDLINE), Scopus, the World Health...

To Improve Nutrition and Reduce the Burden of Disease, FDA Issues Food Industry Guidance for Voluntarily Reducing Sodium in Processed and Packaged Foods | FDA
https://www.fda.gov/news-events/press-announcements/improve-nutrition-and-reduce-burden-disease-fda-issues-food-industry-guidance-voluntarily-reducing

Oct 13th, 2021 - For Immediate Release: October 13, 2021 Statement From: Janet Woodcock, M.D. Acting Commissioner of Food and Drugs - Food and Drug Administration Susan T. Mayne, Ph.D. Director - Center for Food Safety and Applied Nutrition (CFSAN) Español A cornerstone of the U.S. Food and Drug Administration’s public health mission is to reduce the burden of chronic disease through improved nutrition. As a na...

The Association between the Community SARS Exposure and Allostatic Load among Chinese O...
https://doi.org/10.1111/jgs.17516
Journal of the American Geriatrics Society; Ye X, He P

Oct 13th, 2021 - Previous studies have found that Severe Acute Respiratory Syndrome (SARS) was associated with the physical and psychological stress of those infected. However, research is sparse regarding the long-term health consequence of community SARS exposure for older adults. Using data from the 2011 and 2015 China Health and Retirement Longitudinal Study (CHARLS), we estimated multilevel regression mode...

Pharmacotherapy for hypertensive urgency and emergency in COVID-19 patients.
https://doi.org/10.1080/14656566.2021.1990264
Expert Opinion on Pharmacotherapy; Angeli F, Verdecchia P et. al.

Oct 13th, 2021 - Hypertension is a common chronic disorder in patients hospitalised for coronavirus disease 2019 (COVID-19). Furthermore, an exaggerated cardiovascular response with persistently raised blood pressure during hospitalization seems independently associated with in-hospital all-cause mortality, intensive care unit admission and heart failure. However, the real burden of elevated blood pressure duri...

Association between air pollution and COVID-19 mortality and morbidity.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8505468
Internal and Emergency Medicine; Semczuk-Kaczmarek K, Rys-Czaporowska A et. al.

Oct 13th, 2021 - Coronavirus disease (COVID-19) pandemic is affecting the world unevenly. One of the highest numbers of cases were recorded in the most polluted regions worldwide. The risk factors for severe COVID-19 include diabetes, cardiovascular, and respiratory diseases. It has been known that the same disease might be worsened by chronic exposure to air pollution. The study aimed to determine whether long...

FDA Staff 'Meh' on Moderna Booster
https://www.medpagetoday.com/infectiousdisease/covid19vaccine/94996

Oct 12th, 2021 - Data from an ongoing clinical trial found that a booster dose of Moderna's COVID-19 vaccine produced an immune response with no serious safety concerns, FDA staff said in briefing documents released on Tuesday. However, similar to the Pfizer COVID-19 booster trial, the sample size is small, with 149 participants receiving a half-dose 50 μg booster at 6-8 months following the two-dose primary se...

Earlier-Life CAC Scans; Omega-3s and Afib; RV vs LV Abnormalities in COVID
https://www.medpagetoday.com/cardiology/prevention/94991

Oct 12th, 2021 - Should some individuals at risk of atherosclerotic cardiovascular disease start getting coronary artery calcium scans in their mid-to-late 30s? (Journal of the American College of Cardiology) IV thrombolytics may be safe for stroke patients with unruptured intracranial aneurysms, a single-center study found. (Neurology) Major thromboembolism and death were less likely when hospitalized COVID-19...

Longitudinal association between adiposity measures and regression of prediabetes/diabe...
https://doi.org/10.1016/j.numecd.2021.07.005
Nutrition, Metabolism, and Cardiovascular Diseases : NMCD; Modi A, Gadhavi R et. al.

Oct 12th, 2021 - The recent COVID-19 pandemic has further increased the importance of reducing obesity and prediabetes/diabetes. We aimed to evaluate the association between adiposity and regression of prediabetes/diabetes. The San Juan Overweight Adults Longitudinal Study (SOALS) included 1351 individuals with overweight/obesity, aged 40-65, free of major cardiovascular diseases and physician diagnosed diabete...