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COVID-19 Vaccines and the Skin: The Landscape of Cutaneous Vaccine Reactions Worldwide.
https://doi.org/10.1016/j.det.2021.05.016
Dermatologic Clinics; Sun Q, Fathy R et. al.

Sep 25th, 2021 - In 2021, we entered a new phase of the COVID-19 pandemic. As mass vaccinations are underway and more vaccines are approved, it is important to recognize cutaneous adverse events. We review the dermatologic manifestations of COVID-19 vaccines as reported in clinical trial data and summarize additional observational reports of skin reactions to COVID-19 vaccines. Early-onset local injection react...

COVID-19-related oral mucosa lesions among confirmed SARS-CoV-2 patients: a systematic ...
https://doi.org/10.1111/ijd.15889
International Journal of Dermatology; Erbaş GS, Botsali A et. al.

Sep 23rd, 2021 - Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the virus responsible for coronavirus disease 2019 (COVID-19), which manifests as a flu-like respiratory infection affecting multiple organ systems, including the gastrointestinal system, central nervous system, cardiovascular system, skin, and mucosa. In this review, we investigated the literature on specific manifestations of COV...

Urticarial Vasculitis: A Potential Signpost for Multisystem Inflammatory Syndrome in Ch...
https://doi.org/10.1111/cup.14134
Journal of Cutaneous Pathology; Gosnell HL, Grider DJ

Sep 16th, 2021 - Multisystem inflammatory syndrome in children (MIS-C) is a rare and serious complication of Sars-Cov-2 infection. Dermatologic manifestations are present in the majority of patients. Skin lesions found in children with MIS-C are classified into four categories: morbilliform, reticulated, scarlatiniform, and urticarial lesions. Clinicopathologic characterization within these categories is limite...

Severe and life-threatening COVID-19-related mucocutaneous eruptions: A systematic review.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8420487
International Journal of Clinical Practice; Mashayekhi F, Seirafianpour F et. al.

Aug 20th, 2021 - Earlier diagnosis and the best management of virus-related, drug-related or mixed severe potentially life-threatening mucocutaneous reactions of COVID-19 patients are of great concern. These patients, especially hospitalized cases, are usually in a complicated situation (due to multi-organ failures), which makes their management more challenging. In such consultant cases, achieving by the defin...

Cutaneous manifestations of COVID-19 in children (and adults): A virus that does not di...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7604214
Clinics in Dermatology; Lavery MJ, Bouvier CA et. al.

Jul 18th, 2021 - Coronavirus disease 2019 (COVID-19) is caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a beta coronavirus with a characteristic S-glycoprotein spike on the cell surface. Initial reports did not include cutaneous manifestations as a feature of COVID-19; however, there is a growing repertoire of reports demonstrating an array of dermatologic manifestations on the skin ...

Dermatologic manifestations of COVID-19-associated multisystem inflammatory syndrome in...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7604155
Clinics in Dermatology; Brumfiel CM, DiLorenzo AM et. al.

Jul 18th, 2021 - Multisystem inflammatory syndrome in children (MIS-C) affects a small percentage of pediatric patients infected with COVID-19 and is characterized by fever, laboratory evidence of inflammation, multisystem involvement, and severe illness necessitating hospitalization. Skin findings are often present in these patients, and when initially compared with Kawasaki disease, they likely represent dist...

COVID-19: The experience from Italy.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7746129
Clinics in Dermatology; Recalcati S, Gianotti R et. al.

May 12th, 2021 - A wide range of cutaneous signs are attributed to COVID-19 infection. This retrospective study assesses the presence and impact of dermatologic manifestations related to the spread of COVID-19 in Lombardy, the geographic district with the first outbreak in Italy. A cohort of 345 patients with laboratory confirmed COVID-19 was collected from February 1, 2020 to May 31, 2020. Cutaneous signs and ...

Acral Gangrene: Ugly Cousin of "COVID Toes" in Multisystem Inflammatory Syndrome in Chi...
https://doi.org/10.1097/INF.0000000000003181
The Pediatric Infectious Disease Journal; Chaudhary H, Mohan M et. al.

May 5th, 2021 - A spectrum of dermatologic manifestations has been reported in multisystem inflammatory syndrome in children associated with SARS-CoV-2 infection. We report 2 patients with multisystem inflammatory syndrome in children and severe cardiovascular dysfunction who developed acral gangrene. Both responded well to therapy and recovered in the follow-up.

Cutaneous Manifestations of COVID-19.
https://doi.org/10.12788/cutis.0176
Cutis Schwartzberg L, Lin A et. al.

Apr 24th, 2021 - Patients with coronavirus disease 2019 (COVID-19) present with multisystem signs and symptoms, including dermatologic manifestations. The recent literature has revealed that dermatologic manifestations of COVID-19 often are early onset and provide helpful cues to a timely diagnosis. We compiled the relevant emerging literature regarding the dermatologic manifestations of severe acute respirator...

Case Report of Two Patients With COVID-19 and Sacral Pressure Injuries Associated with ...
https://doi.org/10.1097/01.ASW.0000744356.54317.c2
Advances in Skin & Wound Care; Elkhatib R, Giunta G et. al.

Apr 20th, 2021 - During the COVID-19 pandemic, an increasing number of patients have been admitted to the ICU with severe respiratory complications requiring prolonged supine positioning. Recently, many case reports have been published regarding dermatologic manifestations associated with COVID-19. However, there is little information about the clinical features of these manifestations. Pyoderma gangrenosum (PG...

Localized Scarlatiniform Rash of the Ears and Antecubital Fossa in COVID-19.
https://doi.org/10.3122/jabfm.2021.S1.200152
Journal of the American Board of Family Medicine : JABFM; Phamduy TT, Young DM et. al.

Feb 25th, 2021 - The worldwide spread of the novel coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has led to a global pandemic since its identification in Wuhan, China in December 2019.1 Few cases of COVID-19-associated dermatologic manifestations have been reported in the literature to date. This report describes the clinical features of a localized p...

Acute urticaria preceding other COVID-19-associated manifestations-A case report.
https://doi.org/10.1111/pde.14505
Pediatric Dermatology; Chen V, Escandon Brehm J et. al.

Jan 8th, 2021 - The novel coronavirus SARS-CoV-2 has been associated with a variety of dermatologic manifestations, often the predominant finding in otherwise asymptomatic or oligosymptomatic patients. Urticarial eruption is one example, but few cases have been reported among pediatric patients. We present a case of acute urticaria in a 6-month-old boy preceding other COVID-19 symptoms. The suspicion of a poss...

Derm Symptoms Signal MIS-C in Kids
https://www.medpagetoday.com/infectiousdisease/covid19/90108

Dec 9th, 2020 - Most children with multi-system inflammatory syndrome (MIS-C) had mucocutaneous findings, a small case series in New York City found. Among 35 children, 29 with MIS-C exhibited these sequelae, with conjunctival injection, palmoplantar erythema, and lip hyperemia the most common, reported Vikash Oza, MD, of New York University Grossman School of Medicine, and colleagues, writing in a brief repor...

Dermatologic manifestations of COVID-19: a comprehensive systematic review.
https://doi.org/10.1111/ijd.15168
International Journal of Dermatology; Mirza FN, Malik AA et. al.

Nov 4th, 2020 - Recent reports have suggested that there may be dermatologic manifestations of COVID-19. We searched 12 databases for peer-reviewed or pre-print published studies until July 15, 2020, for this PRISMA-compliant review (CRD42020182050). We used the Oxford Center for Evidence-Based Medicine Levels of Evidence to facilitate data synthesis. From 86 retrieved studies, we collated data on 2,560 patien...

An Autopsy Review: "COVID Toes".
https://doi.org/10.1097/DAD.0000000000001827
The American Journal of Dermatopathology; Yilmaz MM, Szabolcs MJ et. al.

Oct 16th, 2020 - "Severe acute respiratory syndrome coronavirus-2" (SARS-CoV-2) infection has variable described dermatologic manifestations. "COVID (coronavirus disease) toes" became a hallmark of the disease in young and largely asymptomatic patients, who may have negative test results for SARS-CoV-2. Pernio (chilblains)-like lesions are seen mostly in infected pediatric patients and are purple painful, frequ...

A 47-Year-Old Hispanic Man Who Developed Cutaneous Vasculitic Lesions and Gangrene of t...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7533950
The American Journal of Case Reports; Adekiigbe R, Ugbode F et. al.

Oct 2nd, 2020 - BACKGROUND Coronavirus disease 2019 (COVID-19) is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which originated in Wuhan, China, in late 2019 and has led to an ongoing pandemic. COVID-19 typically affects the respiratory tract and mucous membranes, leading to pathological involvement of various organ systems. Although patients usually present with fever, cough, and fa...

How Kodak Gold Contributed to Bias in Dermatology
https://www.medscape.com/viewarticle/938018

Sep 30th, 2020 - A recent review looked at all articles describing skin manifestations associated with COVID-19 — 46 articles with a total of 130 clinical images — and found none that documented dermatologic conditions in people with dark skin. This was despite the disproportionate incidence of the disease in Black, Latinx, and Native American/American Indian populations of color. Temitayo A. Ogunleye, MD What ...

How Kodak Gold Contributed to Bias in Dermatology
https://www.staging.medscape.com/viewarticle/938018

Sep 30th, 2020 - A recent review looked at all articles describing skin manifestations associated with COVID-19 — 46 articles with a total of 130 clinical images — and found none that documented dermatologic conditions in people with dark skin. This was despite the disproportionate incidence of the disease in Black, Latinx, and Native American/American Indian populations of color. Temitayo A. Ogunleye, MD What ...

Timing of PCR and antibody testing in patients with COVID-19-associated dermatologic ma...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7482613
Journal of the American Academy of Dermatology; Freeman EE, McMahon DE et. al.

Sep 14th, 2020 - Timing of PCR and antibody testing in patients with COVID-19-associated dermatologic manifestations.|2020|Freeman EE,McMahon DE,Hruza GJ,Lipoff JB,French LE,|

Investigating the spectrum of dermatologic manifestations in COVID-19 infection in seve...
https://doi.org/10.1111/cup.13867
Journal of Cutaneous Pathology REFERENCES; Occidental M, Flaifel A et. al.

Sep 9th, 2020 - COVID-19, an infectious disease caused by the novel coronavirus, was initially identified in Wuhan, China, in December 2019. By March 2020, it was declared a pandemic by the World Health Organization. Although most findings have been reported in the lungs, primarily due to catastrophic respiratory decline, other organs, including the skin, are affected. Recent reports have been published descri...