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Assessment of hypertension and other factors associated with the severity of disease in...
https://doi.org/10.1371/journal.pone.0273012
PloS One; Ashamo AY, Bekele A et. al.

Aug 16th, 2022 - Various reports suggested that pre-existing medical illnesses, including hypertension and other demographic, clinical, and laboratory factors, could pose an increased risk of disease severity and mortality among COVID-19 patients. This study aimed to assess the relation of hypertension and other factors to the severity of COVID-19 pneumonia in patients discharged from Eka Kotebe Hospital in Jun...

Higher Cardiac COVID Risks in Pregnancy Require Team Care
https://www.medscape.com/viewarticle/979238

Aug 15th, 2022 - Management of the cardiac complications of COVID-19 during pregnancy requires a "pregnancy heart team" to optimize patient care, the American College of Cardiology (ACC) Cardiovascular Disease in Women committee writes in a new report. This multidisciplinary team can include providers comfortable with high-risk pregnancy, obstetric anesthesia, cardiology, critical care, and neonatal care, depen...

B cell contribution to immunometabolic dysfunction and impaired immune responses in obe...
https://doi.org/10.1093/cei/uxac079
Clinical and Experimental Immunology; Oleinika K, Slisere B et. al.

Aug 13th, 2022 - Obesity increases the risk of type 2 diabetes mellitus, cardiovascular disease, fatty liver disease, and cancer. It is also linked with more severe complications from infections, including COVID-19, and poor vaccine responses. Chronic, low-grade inflammation and associated immune perturbations play an important role in determining morbidity in people living with obesity. The contribution of B c...

COVID-19 in Kidney Transplant Recipients With Diabetes Mellitus: A Propensity Score Mat...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9357874
Transplant International : Official Journal of the Europe... Rangel ÉB, de Lucena DD et. al.

Aug 13th, 2022 - Kidney transplant recipients present higher rates of pre-existing comorbidities, in particular diabetes mellitus (DM), hypertension, and cardiac disease. We aimed to verify the main risk factors related to DM that contribute to COVID-19 progression and mortality in a kidney transplant setting. From March to August 2020, we evaluated 300 kidney transplant recipients affected by COVID-19. We used...

Changes in spending, utilization, and quality of care among Medicare accountable care o...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9374212
PloS One; Yan BW, Shashoua M et. al.

Aug 13th, 2022 - The COVID pandemic disrupted health care spending and utilization, and the Medicare Shared Savings Program (MSSP), Medicare's largest value-based payment model with 11.2 million assigned beneficiaries, was no exception. Despite COVID, the 513 accountable care organizations (ACO) in MSSP returned a program record $1.9 billion in net savings to Medicare in 2020. To understand the extent of COVID'...

The COVID-19 pandemic and disruptions to essential health services in Kenya: a retrospe...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9363041
The Lancet. Global Health; Kiarie H, Temmerman M et. al.

Aug 13th, 2022 - Public health emergencies can disrupt the provision of and access to essential health-care services, exacerbating health crises. We aimed to assess the effect of the COVID-19 pandemic on essential health-care services in Kenya. Using county-level data routinely collected from the health information system from health facilities across the country, we used a robust mixed-effect model to examine ...

Eosinophil Levels, Neutrophil-Lymphocyte Ratio, and Platelet-Lymphocyte Ratio in the Cy...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9346569
International Journal of Clinical Practice; Koc I, Unalli Ozmen S

Aug 12th, 2022 - In the early stages of the COVID-19 pandemic, elevated inflammatory cytokine levels, particularly interleukin-6 (IL-6), were detected in patients with cytokine storm (CS). This study aimed to investigate levels, diagnostic usefulness, and optimal cutoff values of monocyte, eosinophil, neutrophil-lymphocyte ratio (NLR), and platelet-lymphocyte ratio (PLR) in CS of patients with COVID-19 and also...

Risk factors for mortality among hospitalized COVID-19 patients in Northern Ethiopia: A...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9371316
PloS One; Abebe HT, Mulugeta A et. al.

Aug 12th, 2022 - COVID-19 is a deadly pandemic caused by an RNA virus that belongs to the family of CORONA virus. To counter the COVID-19 pandemic in resource limited settings, it is essential to identify the risk factors of COVID-19 mortality. This study was conducted to identify the social and clinical determinants of mortality in COVID-19 patients hospitalized in four treatment centers of Tigray, Northern Et...

Impact of the COVID-19 Pandemic on Diabetes Care for Adults With Type 2 Diabetes in Ont...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9059339
Canadian Journal of Diabetes; Moin JS, Troke N et. al.

Aug 12th, 2022 - The COVID-19 pandemic and related public health prevention measures have led to a disruption of the delivery of routine care and may have had an impact on the quality of diabetes care. Our aim in this study was to evaluate the extent to which structure, process and outcome quality measures in diabetes care changed in the first 6 months of the pandemic compared with previous periods. A before-an...

Incidence of diabetic ketoacidosis during COVID-19 pandemic: a meta-analysis of 124,597...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9366798
Pediatric Research; Elgenidy A, Awad AK et. al.

Aug 12th, 2022 - Diabetic ketoacidosis (DKA) is a potentially life-threatening complication of type 1 diabetes mellitus (T1DM) that has increased during the COVID-19 pandemic. This study will not only shed light on such life-threatening complications but also be a step to increase the awareness of healthcare providers about such complications in the upcoming pandemic waves and increased dependence on telemedici...

Improved CGM Glucometrics and More Visits in Pediatric Type 1 Diabetes using Telemedici...
https://doi.org/10.1210/clinem/dgac476
The Journal of Clinical Endocrinology and Metabolism; Kaushal T, Tinsley LJ et. al.

Aug 11th, 2022 - The COVID-19 pandemic led to rapid adoption of telemedicine for the care of youth with type 1 diabetes (T1D). We assessed the utility of a primarily virtual care model by comparing glucometrics from a pediatric sample with T1D using continuous glucose monitoring (CGM) both before and during the pandemic. Pediatric patients ages 1-17 years with T1D duration ≥1 year if ≥6 years old or ≥6 months i...

Healthcare Use Prior to Diabetes Diagnosis in Children Before and During COVID.
https://doi.org/10.1542/peds.2022-058349
Pediatrics Shulman R, Nakhla M et. al.

Aug 11th, 2022 - During COVID-19, healthcare systems reorganized with less ambulatory care and a shift to virtual care (1). There was an increase in diabetic ketoacidosis (DKA), a preventable, life-threatening condition, at diabetes onset in children during COVID-19 (2). DKA at diabetes onset has been attributed to delays in seeking care, missed diagnosis or delays in referral following a primary healthcare con...

Pathogenic role of cytokines in COVID-19, its association with contributing co-morbidit...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9365214
Inflammopharmacology Tanveer A, Akhtar B et. al.

Aug 11th, 2022 - The Covid-19, a threatening pandemic, was originated from China in December 2019 and spread quickly to all over the world. The pathogenesis of coronavirus is linked with the disproportionate response of the immune system. This involves the systemic inflammatory reaction which is characterized by marked pro-inflammatory cytokine release commonly known as cytokine release storm (CRS). The pro inf...

Convalescent plasma therapy for patients with severe COVID-19: A case series study.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9351516
Medicine Huang J, Weng H et. al.

Aug 11th, 2022 - Coronavirus disease 2019 (COVID-19) is a novel acute respiratory infectious disease that can lead to multiple-organ dysfunction in patients with severe disease. However, there is a lack of effective antiviral drugs for COVID-19. Herein, we investigated the efficacy and safety of convalescent plasma (CP) therapy for treating severe COVID-19 in an attempt to explore new therapeutic methods. The c...

COVID-19 Exacerbates Insulin Resistance During Diabetic Ketoacidosis in Pediatric Patie...
https://doi.org/10.2337/dc22-0396
Diabetes Care; Keiner ES, Slaughter JC et. al.

Aug 10th, 2022 - Although mortality from coronavirus disease 2019 (COVID-19) among youth with type 1 diabetes is rare, severe acute respiratory syndrome coronavirus 2 is associated with increased pediatric hospitalizations for diabetic ketoacidosis (DKA). To clarify whether the relationship between COVID-19 and DKA is coincidental or causal, we compared tissue glucose disposal (TGD) during standardized treatmen...

The Impact of the COVID-19 Pandemic on Ethnic Minority Groups With Diabetes.
https://doi.org/10.2337/dc21-2495
Diabetes Care; Khunti K, Feldman EL et. al.

Aug 10th, 2022 - Major ethnic disparities in diabetes care, especially for intermediate outcomes and diabetes complications, were evident prior to the coronavirus disease 2019 (COVID-19) pandemic. Diabetes is a risk factor for severe COVID-19, and the combination of these ethnic disparities in diabetes care and outcomes may have contributed to the inequity in COVID-19 outcomes for people with diabetes. Overall,...

Metabolic Benefit of Teleconsultation for Diabetes Management During the COVID-19 Pande...
https://doi.org/10.1089/tmj.2022.0090
Telemedicine Journal and E-health : the Official Journal ... Meyer L, Flocard M et. al.

Aug 10th, 2022 - Aim: To investigate the impact of teleconsultation on glycemic control in patients with diabetes during the COVID-19 pandemic. Methods: In this observational prospective study, the main outcome was the comparison of glycated hemoglobin (HbA1c) between patients with or without teleconsultation at 6-month follow-up. Results: From March 17 to May 31, 2020, 610 patients were included, 456 were foll...

Quantitative B and T cell abnormalities in four patients presenting with mucormycosis a...
https://doi.org/10.1136/bcr-2021-247893
BMJ Case Reports; Mandke C, Divekar R et. al.

Aug 10th, 2022 - India saw an unprecedented and rapid rise of invasive coronavirus-associated mucormycosis (CAM) during the delta COVID-19 surge. There is little known about the pathophysiology and if there is a direct causation between the COVID-19 infection and invasive CAM. While the traditional risk factors such as uncontrolled diabetes and other immunocompromising conditions are recognised, there could be ...

Extrapulmonary Manifestations of SARS-CoV-2: A Report of 3 Cases and a Literature Review.
https://doi.org/10.12659/AOT.935874
Annals of Transplantation; Barbachowska A, Gozdowska J et. al.

Aug 10th, 2022 - BACKGROUND COVID-19 disease, caused by the SARS-CoV-2 virus, has been one of the greatest challenges in modern medicine. It is mostly known to affect the pulmonary system, leading to pneumonia and acute respiratory distress syndrome, but there is a growing body of evidence of extrapulmonary manifestations of COVID-19 disease. CASE REPORT This article presents 3 cases of various extrapulmonary s...

Risk factors of SARS-CoV-2 infection in cancer patients pre- and post-vaccination.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9362932
PloS One; Alsagaby SA, Alharbi NK et. al.

Aug 10th, 2022 - Severe complications from COVID-19 and poor responses to SARS-CoV-2 vaccination were commonly reported in cancer patients compared to those without cancer. Therefore, the identification of predisposing factors to SARS-CoV-2 infection in cancer patients would assist in the prevention of COVID-19 and improve vaccination strategies. The literature lacks reports on this topic from the Kingdom of Sa...