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Taste Dysfunction May Linger After COVID-19
https://www.medpagetoday.com/infectiousdisease/covid19/96549

Jan 6th, 2022 - Taste dysfunction may linger after acute COVID-19 infection and may not necessarily be a consequence of olfactory dysfunction, a cross-sectional study in Italy showed. In a group of people who reported losing their sense of taste for months after they had COVID, 42% were found to have true hypogeusia, reported Paolo Boscolo-Rizzo, MD, of the University of Trieste in Italy, and co-authors. Most ...

Metabolic correlates of olfactory dysfunction in COVID-19 and Parkinson's disease (PD) ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8727173
European Journal of Nuclear Medicine and Molecular Imaging; Morbelli S, Chiola S et. al.

Jan 6th, 2022 - Hyposmia is a common feature of COVID-19 and Parkinson's disease (PD). As parkinsonism has been reported after COVID-19, a link has been hypothesized between SARS-CoV2 infection and PD. We aimed to evaluate brain metabolic correlates of isolated persistent hyposmia after mild-to-moderate COVID-19 and to compare them with metabolic signature of hyposmia in drug-naïve PD patients. Forty-four pati...

Isolated Abducens Nerve Palsy in a Patient With COVID-19: A Case Report and Literature ...
https://doi.org/10.1097/NRL.0000000000000382
The Neurologist; Manolopoulos A, Katsoulas G et. al.

Dec 3rd, 2021 - The pandemic of coronavirus disease 2019 (COVID-19) stands as a major global health and social burden. As cases are growing, several other symptoms, besides the typical respiratory ones, are emerging. The involvement of the nervous system is increasingly recognized with manifestations ranging from hyposmia to meningoencephalitis and cranial neuropathies. We report the case of a 41-year-old fema...

Phenotyping of acute and persistent COVID-19 features in the outpatient setting: explor...
https://doi.org/10.1093/cid/ciab978
Clinical Infectious Diseases : an Official Publication Of... Sahanic S, Tymoszuk P et. al.

Dec 2nd, 2021 - Long COVID, defined as presence of COVID-19 symptoms 28 days or more after clinical onset, is an emerging challenge to healthcare systems. The objective of this study was to explore recovery phenotypes in non-hospitalized COVID-19 individuals. A dual cohort, online survey study was conducted between September 2020 and July 2021 in the neighboring European regions Tyrol (TY, Austria, n = 1157) a...

Prevalence of Persistent Olfactory Disorders in Patients With COVID-19: A Psychophysica...
https://doi.org/10.1177/01945998211061511
Otolaryngology--head and Neck Surgery : Official Journal ... Vaira LA, Salzano G et. al.

Nov 24th, 2021 - The purpose of this multicenter case-control study was to evaluate a group of patients at least 1 year after coronavirus disease 2019 (COVID-19) with Sniffin' Sticks tests and to compare the results with a control population to quantify the potential bias introduced by the underlying prevalence of olfactory dysfunction (OD) in the general population. The study included 170 cases and 170 control...

Olfactory evaluation in hospitalised and self-isolated patients with COVID-19: a single...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8594974
Postgraduate Medical Journal; Klarendic M, Zupanic E et. al.

Nov 14th, 2021 - Smell loss is a common symptom of COVID-19 infection. Majority of the studies that evaluated olfactory impairment in COVID-19 used questionnaires (subjective smell evaluations) and did not compare the results with objective or semiobjective measures of smell. We performed smell testing in hospitalised and self-isolated patients with COVID-19 and control participants. Fifty-five COVID-19 and 44 ...

Bariatric Surgery and COVID-19: What We Have Learned from the Pandemic in Iran: a Retro...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8556836
Obesity Surgery; Moradpour G, Amini M et. al.

Oct 31st, 2021 - Little is known about the symptoms of coronavirus disease 2019 (COVID-19) on patients with morbid obesity following bariatric surgery (BS) in Iran. Thus, we sought to investigate the symptoms and effect of COVID-19 in patients with morbid obesity following, or candidates for, BS in Iran. In this retrospective observational cohort study, we enrolled 236 morbid obese patients following (surgical ...

The taste of the pandemic-contemporary review on the current state of research on gusta...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8653126
International Forum of Allergy & Rhinology; Hintschich CA, Niv MY et. al.

Oct 28th, 2021 - Subjectively perceived impairment of taste is a common and distinct symptom of coronavirus disease 2019 (COVID-19). Large meta-analyses identified this symptom in approximately 50% of cases. However, this high prevalence is not supported by blinded and validated psychophysical gustatory testing, which showed a much lower prevalence in up to 26% of patients. This discrepancy may be due to misint...

Neurological symptoms of COVID-19 infection; a cross-sectional study on hospitalized CO...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8502683
Clinical Neurology and Neurosurgery; Nejad JH, Allahyari F et. al.

Oct 27th, 2021 - Coronavirus disease 2019 (COVID-19), a global issue now, can have a variety of clinical manifestations. Hundreds of articles have discussed different aspects of this infectious disease, such as physiopathology, epidemiology, clinical manifestations and treatment protocols. Recently, neurological manifestations of the disease have been found to be pretty common among COVID-19 patients. Here, neu...

Residual olfactory dysfunction in coronavirus disease 2019 patients after long term rec...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8315939
Journal of Clinical Neuroscience : Official Journal of Th... Zhu Y, Cao M et. al.

Oct 18th, 2021 - Hyposmia is among the most common symptoms of COVID-19 patients. Previous research has mainly described this issue at the disease's early stages. Because olfactory impairment can indicate neurological degeneration, we investigated the possibility of permanent olfactory damage by assessing hyposmia during the late recovery stage of COVID-19 patients. Ninety-five patients were assessed with the B...

Patterns and clinical outcomes of olfactory and gustatory disorders in six months: Pros...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8481118
American Journal of Otolaryngology; Teaima AA, Salem OM et. al.

Oct 10th, 2021 - This study aims to comprehensively evaluate olfactory and gustatory dysfunctions during the COVID-19 pandemic regarding onset, course, associated symptoms, prognosis and relation to patients' demographics, treatment received and other symptoms. This is a prospective study conducted on patients proven to be infected with COVID-19 and with olfactory/gustatory dysfunction symptoms. Detailed histor...

Neuropsychiatric manifestations of COVID-19, potential neurotropic mechanisms, and ther...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8482959
Translational Psychiatry; Han Y, Yuan K et. al.

Oct 2nd, 2021 - The coronavirus disease 2019 (COVID-19) pandemic has caused large-scale economic and social losses and worldwide deaths. Although most COVID-19 patients have initially complained of respiratory insufficiency, the presence of neuropsychiatric manifestations is also reported frequently, ranging from headache, hyposmia/anosmia, and neuromuscular dysfunction to stroke, seizure, encephalopathy, alte...

Quantitative Analysis of the Olfactory System in COVID-19: An MR Imaging Study.
https://doi.org/10.3174/ajnr.A7278
AJNR. American Journal of Neuroradiology; Altunisik E, Baykan AH et. al.

Sep 25th, 2021 - Anosmia or hyposmia, often accompanied by changes in taste, is recognized as a common symptom that can assist in the diagnosis of coronavirus disease 2019 (COVID-19). The pathogenesis of olfactory dysfunction in COVID-19 is not yet fully understood. MR imaging represents a useful anatomic imaging method for the evaluation of olfactory dysfunction associated with varying etiologies, including vi...

A Systematic Review of Imaging Studies in Olfactory Dysfunction Secondary to COVID-19.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8403662
Academic Radiology; Keshavarz P, Haseli S et. al.

Sep 23rd, 2021 - Hyposmia/anosmia is common among patients with coronavirus disease-2019 (COVID-19). Various imaging modalities have been used to assess olfactory dysfunction in COVID-19. In this systematic review, we sought to categorize and summarize the imaging data in COVID-19-induced anosmia. Eligible articles were included after a comprehensive review using online databases including Google scholar, Scopu...

Impairments in odour detection and hedonic ratings of unpleasant smells in asymptomatic...
https://doi.org/10.1111/ejn.15430
The European Journal of Neuroscience; Walsh-Messinger J, Kaouk S et. al.

Aug 24th, 2021 - Sudden olfactory loss in the absence of concurrent nasal congestion is now a well-recognized symptom of COVID-19. We examined olfaction using standardized objective tests of odour detection, identification and hedonics collected from asymptomatic university students before and as SARS-CoV-2 emerged locally. Olfactory performance of students who were tested when the virus is known to be endemic ...

The Frequency and Clinical Assessment of COVID-19 in Patients With Chronic Rhinosinusitis.
https://doi.org/10.1177/01455613211038070
Ear, Nose, & Throat Journal; Akhlaghi A, Darabi A et. al.

Aug 21st, 2021 - Chronic rhinosinusitis (CRS), as an inflammatory airway disease, could be a risk factor for COVID-19 patients. This study aimed to investigate the frequency and severity of symptoms of COVID-19 in patients with CRS and to assess the association between the status of CRS symptoms and the quality of life (QoL) of the patients. In this observational and cross-sectional study, 207 adult CRS patient...

Neurological symptoms and axonal damage in COVID-19 survivors: are there sequelae?
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8346772
Immunologic Research; Bozzetti S, Ferrari S et. al.

Aug 8th, 2021 - The persistence of neurological symptoms after SARS-CoV-2 infection, as well as the presence of late axonal damage, is still unknown. We performed extensive systemic and neurological follow-up evaluations in 107 out of 193 consecutive patients admitted to the COVID-19 medical unit, University Hospital of Verona, Italy between March and June 2020. We analysed serum neurofilament light chain (NfL...

Interventions for the treatment of persistent post-COVID-19 olfactory dysfunction.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8406942
The Cochrane Database of Systematic Reviews; O'Byrne L, Webster KE et. al.

Jul 23rd, 2021 - Olfactory dysfunction is an early and sensitive marker of COVID-19 infection. Although self-limiting in the majority of cases, when hyposmia or anosmia persists it can have a profound effect on quality of life. Little guidance exists on the treatment of post-COVID-19 olfactory dysfunction, however several strategies have been proposed from the evidence relating to the treatment of post-viral an...

Correlations Between Olfactory Psychophysical Scores and SARS-CoV-2 Viral Load in COVID...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8441733
The Laryngoscope; Vaira LA, Deiana G et. al.

Jul 22nd, 2021 - The aim of this study was to evaluate the correlations between the severity and duration of olfactory dysfunctions (OD), assessed with psychophysical tests, and the viral load on the rhino-pharyngeal swab determined with a direct method, in patients affected by coronavirus disease 2019 (COVID-19). Prospective cohort study. Patients underwent psychophysical olfactory assessment with Connecticut ...

Predictive factors of smell recovery in a clinical series of 288 coronavirus disease 20...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8444937
European Journal of Neurology; Saussez S, Sharma S et. al.

Jun 23rd, 2021 - The aim was to evaluate potential predictive factors of smell recovery in a clinical series of 288 patients presenting olfactory dysfunction (OD) related to coronavirus disease 2019 (COVID-19). Potential correlations were sought between epidemiological, clinical and immunological characteristics of patients and the persistence of OD at 60 days. COVID-19 positive patients presenting OD were pros...