×
Clinical utility of perfusion (Q)-single-photon emission computed tomography (SPECT)/CT...
https://doi.org/10.1007/s00259-020-05043-y
European Journal of Nuclear Medicine and Molecular Imaging; Das JP, Yeh R et. al.

Sep 22nd, 2020 - We reviewed the clinical utility of perfusion (Q)-single-photon emission computed tomography (SPECT)/CT for diagnosing pulmonary embolus (PE) in patients hospitalized with severe acute respiratory syndrome coronavirus 2 (SARS-CoV2). Following the World Health Organization's declaration of a global pandemic, our department policy recommended Q-only SPECT/CT for all patients undergoing nuclear me...

COVID19XrayNet: A Two-Step Transfer Learning Model for the COVID-19 Detecting Problem B...
https://doi.org/10.1007/s12539-020-00393-5
Interdisciplinary Sciences, Computational Life Sciences; Zhang R, Guo Z et. al.

Sep 22nd, 2020 - The novel coronavirus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused a major pandemic outbreak recently. Various diagnostic technologies have been under active development. The novel coronavirus disease (COVID-19) may induce pulmonary failures, and chest X-ray imaging becomes one of the major confirmed diagnostic technologies. The very limited number of publicly availab...

Incidence of Barotrauma in Patients With COVID-19 Pneumonia During Prolonged Invasive M...
https://doi.org/10.1177/0885066620954364
Journal of Intensive Care Medicine; Udi J, Lang CN et. al.

Sep 22nd, 2020 - SARS-CoV2 can cause pulmonary failure requiring prolonged invasive mechanical ventilation (MV). Lung protective ventilation strategies are recommended in order to minimize ventilator induced lung injury. Whether patients with COVID-19 have the same risk for complications including barotrauma is still unknown. Therefore, we investigated barotrauma in patients with COVID-19 pneumonia requiring pr...

Role of computed tomography in COVID-19.
https://doi.org/10.1016/j.jcct.2020.08.013
Journal of Cardiovascular Computed Tomography; Pontone G, Scafuri S et. al.

Sep 21st, 2020 - Coronavirus disease 2019 (COVID-19) has become a rapid worldwide pandemic. While COVID-19 primarily manifests as an interstitial pneumonia and severe acute respiratory distress syndrome, severe involvement of other organs has been documented. In this article, we will review the role of non-contrast chest computed tomography in the diagnosis, follow-up and prognosis of patients affected by COVID...

Xuebijing injection in the treatment of COVID-19: a retrospective case-control study.
https://doi.org/10.21037/apm-20-1478
Annals of Palliative Medicine; Guo H, Zheng J et. al.

Sep 21st, 2020 - Neither a vaccine nor specific therapeutic drugs against 2019 novel coronavirus have been developed. Some studies have shown that Xuebijing injection (XBJ) can exert an anti-inflammatory effect by inhibiting the production of interleukin-6 (IL-6), tumor necrosis factor alpha (TNF-α), and other cytokines. This study aimed to investigate the effect of XBJ on coronavirus disease 2019 (COVID-19) an...

The success of virtual clinics during COVID-19: A closed loop audit of the British orth...
https://doi.org/10.1016/j.injury.2020.09.012
Injury Dunkerley S, Kurar L et. al.

Sep 21st, 2020 - COVID-19 has had profound management implications for orthopaedic management due to balancing patient outcomes with clinical safety and limited resources. The BOAST guidelines on outpatient orthopaedic fracture management took a pragmatic approach. At Great Western Hospital, Swindon, a closed loop audit was performed looking at a selection of these guidelines, to assess if our initial changes w...

Radiographic and clinical neurologic manifestations of COVID-19 related hypoxemia.
https://doi.org/10.1016/j.jns.2020.117119
Journal of the Neurological Sciences; Radnis C, Qiu S et. al.

Sep 21st, 2020 - The novel coronavirus SARS-CoV-2 is known to cause hypoxemia and acute respiratory distress syndrome (ARDS) in a significant portion of those with severe disease. Survivors of critical illness and ARDS often experience neurocognitive impairment but, to date, there is scant literature correlating radiographic hypoxic brain injury to hypoxemia related to ARDS. In this case series, we describe thr...

Interobserver and Intraobserver Variability in the CT Assessment of COVID-19 Based on R...
https://doi.org/10.1016/j.acra.2020.08.038
Academic Radiology; Hadied MO, Patel PY et. al.

Sep 19th, 2020 - To assess the interobserver and intraobserver agreement of fellowship trained chest radiologists, nonchest fellowship-trained radiologists, and fifth-year radiology residents for COVID-19-related imaging findings based on the consensus statement released by the Radiological Society of North America (RSNA). A survey of 70 chest CTs of polymerase chain reaction (PCR)-confirmed COVID-19 positive a...

Transthoracic echocardiographic findings in patients admitted with SARS-CoV-2 infection.
https://doi.org/10.1111/echo.14835
Echocardiography (Mount Kisco, N.Y.) REFERENCES; Schott JP, Mertens AN et. al.

Sep 19th, 2020 - Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2)-infected patients commonly have elevated troponin and D-dimer levels, but limited imaging exists to support most likely etiologies in efforts to avoid staff exposure. The purpose of this study was to report transthoracic echocardiographic (TTE) findings in SARS-CoV-2 patients with correlating troponin and D-dimer levels. We identified...

αlphavbeta6 targeted molecular PET/CT imaging of lung post SARS-CoV-2 infection.
https://doi.org/10.2967/jnumed.120.255364
Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine; Foster CC, Davis RA et. al.

Sep 19th, 2020 - The true impact and long-term damage to organs such as the lungs following severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection remain to be determined. Non-invasive molecularly targeted imaging may play a critical role to aid in the visualization and understanding of the systemic damage. We have identified αvβ6 as molecular target; an epithelium-specific cell surface receptor...

Differential diagnosis for suspected cases of coronavirus disease 2019: a retrospective...
https://doi.org/10.1186/s12879-020-05383-y
BMC Infectious Diseases; Chi Q, Dai X et. al.

Sep 19th, 2020 - Since December 2019, the coronavirus disease 2019 (COVID-19) has infected more than 12,322,000 people and killed over 556,000 people worldwide. However, Differential diagnosis remains difficult for suspected cases of COVID-19 and need to be improved to reduce misdiagnosis. Sixty-eight cases of suspected COVID-19 treated in Wenzhou Central Hospital from January 21 to February 20, 2020 were divid...

Imaging of children with COVID-19: experience from a tertiary children's hospital in th...
https://doi.org/10.1007/s00247-020-04830-x
Pediatric Radiology; Biko DM, Ramirez-Suarez KI et. al.

Sep 18th, 2020 - Imaging of novel coronavirus disease 2019 (COVID-19) has been described in adults, but children have milder forms of disease. Pediatric imaging descriptions are of asymptomatic children, raising the question of whether imaging is needed in this patient group. To describe the utilization and imaging findings in children with COVID-19 along with the comorbidities, treatment and short-term outcome...

Delirium in COVID-19: epidemiology and clinical correlations in a large group of patien...
https://doi.org/10.1007/s40520-020-01699-6
Aging Clinical and Experimental Research; Ticinesi A, Cerundolo N et. al.

Sep 18th, 2020 - Delirium incidence and clinical correlates in coronavirus disease-19 (COVID-19) pneumonia are still poorly investigated. To describe the epidemiology of delirium in patients hospitalized for suspect COVID-19 pneumonia during the pandemic peak in an academic hospital of Northern Italy, identify its clinical correlations and evaluate the association with mortality. The clinical records of 852 pat...

COVID-19 Stroke Apical Lung Examination Study: A Diagnostic and Prognostic Imaging Biom...
https://doi.org/10.3174/ajnr.A6832
AJNR. American Journal of Neuroradiology; Siddiqui J, Bala F et. al.

Sep 18th, 2020 - Diagnosis of coronavirus disease 2019 (COVID-19) relies on clinical features and reverse-transcriptase polymerase chain reaction testing, but the sensitivity is limited. Carotid CTA is a routine acute stroke investigation and includes the lung apices. We evaluated CTA as a potential COVID-19 diagnostic imaging biomarker. This was a multicenter, retrospective study (n = 225) including CTAs of pa...

SARS-CoV-2 infection of African green monkeys results in mild respiratory disease disce...
https://doi.org/10.1371/journal.ppat.1008903
PLoS Pathogens; Hartman AL, Nambulli S et. al.

Sep 18th, 2020 - Vaccines are urgently needed to combat the global coronavirus disease 2019 (COVID-19) pandemic, and testing of candidate vaccines in an appropriate non-human primate (NHP) model is a critical step in the process. Infection of African green monkeys (AGM) with a low passage human isolate of SARS-CoV-2 by aerosol or mucosal exposure resulted in mild clinical infection with a transient decrease in ...

Early Orthopaedic Trauma Outcomes in COVID-19 Infected Patients: A Case Series.
https://doi.org/10.1097/BOT.0000000000001924
Journal of Orthopaedic Trauma; Edwards DN, Arguello AM et. al.

Sep 18th, 2020 - Orthopaedic trauma presents a unique and complex challenge in the initial phase of the coronavirus 2019 (COVID-19) global crisis. Little is currently known about the surgical practices in orthopaedic emergencies in the early days of the COVID-19 outbreak (1). This is a retrospective case series of 10 orthopaedic trauma patients who underwent fracture fixation in March 2020. Of the 10 patients t...

Cerebrospinal fluid confirmed COVID-19-associated encephalitis treated successfully.
https://doi.org/10.1136/bcr-2020-237378
BMJ Case Reports; Kamal YM, Abdelmajid Y et. al.

Sep 17th, 2020 - The COVID-19 pandemic that attracted global attention in December 2019 is well known for its clinical picture that is consistent with respiratory symptoms. Currently, the available medical literature describing the neurological complications of COVID-19 is gradually emerging. We hereby describe a case of a 31-year-old COVID-19-positive patient who was admitted on emergency basis. His clinical p...

The use of imaging in COVID-19-results of a global survey by the International Society ...
https://doi.org/10.1007/s00330-020-07252-3
European Radiology; Blažić I, Brkljačić B et. al.

Sep 17th, 2020 - This survey conducted by the International Society of Radiology and supported by the European Society of Radiology aimed to collect information regarding radiology departments' current practices in the management of patients with COVID-19. Responses from 50 radiology departments involved in the management of COVID-19 patients representing 33 countries across all continents were analyzed. The an...

Pneumothorax in COVID-19 disease- incidence and clinical characteristics.
https://doi.org/10.1186/s12931-020-01504-y
Respiratory Research; Zantah M, Dominguez Castillo E et. al.

Sep 17th, 2020 - Spontaneous pneumothorax is an uncommon complication of COVID-19 viral pneumonia. The exact incidence and risk factors are still unknown. Herein we review the incidence and outcomes of pneumothorax in over 3000 patients admitted to our institution for suspected COVID-19 pneumonia. We performed a retrospective review of COVID-19 cases admitted to our hospital. Patients who were diagnosed with a ...

Trends in clinical presentation of children with COVID-19: a systematic review of indiv...
https://doi.org/10.1038/s41390-020-01161-3
Pediatric Research; Christophers B, Marin BG et. al.

Sep 17th, 2020 - There are sparse patient-level data available for children with novel coronavirus disease (COVID-19). Therefore, there is an urgent need for an updated systematic literature review that analyzes individual children rather than aggregated data in broad age groups. Six databases (MEDLINE, Scopus, Web of Science, CINAHL, Google Scholar, medRxiv) were searched for studies indexed from January 1 to ...