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Plasma Biomarkers Predict COVID Neurologic Complications
https://www.medscape.com/viewarticle/979083

Aug 11th, 2022 - SAN DIEGO – Even after recovery of an acute COVID-19 infection, some patients experience extended or even long-term symptoms that can range from mild to debilitating. Some of these symptoms are neurological: headaches, brain fog, cognitive impairment, loss of taste or smell, and even cerebrovascular complications such stroke. There are even hints that COVID-19 infection could lead to future neu...

Therapeutic Approaches to the Neurologic Manifestations of COVID-19.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9302225
Neurotherapeutics : the Journal of the American Society F... Graham EL, Koralnik IJ et. al.

Jul 22nd, 2022 - As of May 2022, there have been more than 527 million infections with severe acute respiratory disease coronavirus type 2 (SARS-CoV-2) and over 6.2 million deaths from Coronavirus Disease 2019 (COVID-19) worldwide. COVID-19 is a multisystem illness with important neurologic consequences that impact long-term morbidity and mortality. In the acutely ill, the neurologic manifestations of COVID-19 ...

Neuropathic Pain Associated with COVID-19: a Systematic Review of Case Reports.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9214475
Current Pain and Headache Reports; Joshi D, Gyanpuri V et. al.

Jun 23rd, 2022 - Researchers suggests that patients with COVID-19 develop neuropathic pain within weeks or months following infection and that patients with neuropathic pain and COVID-19 sometimes present with deterioration of neurologic complications and pain exacerbation. The objective of this systematic review is to discuss the case-reports having neuropathic pain during and after COVID-19 infection. Case re...

Acute Neurologic Complications of COVID-19 and Postacute Sequelae of COVID-19.
https://doi.org/10.1016/j.ccc.2022.03.002
Critical Care Clinics; Dangayach NS, Newcombe V et. al.

Jun 7th, 2022 - Neurologic complications can be seen in mild to severe COVID-19 with a higher risk in patients with severe COVID-19. These can occur as a direct consequence of viral infection or consequences of treatments. The spectrum ranges from non-life-threatening, like headache, fatigue, malaise, anosmia, dysgeusia, to life-threatening complications, like stroke, encephalitis, coma, Guillain-Barre syndrom...

Neuromuscular complications after COVID-19 vaccination: a series of eight patients
https://pubmed.ncbi.nlm.nih.gov/35499704/
Acta Neurologica Belgica; Leemans W, Antonis S et. al.

May 2nd, 2022 - Background: Several neurologic complications have been reported in close temporal association with both severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection and following vaccination against SARS-CoV-2. Specifically, several cases of Guillain-Barré syndrome (GBS) have been reported in temporal relationship with COVID-19 vaccination, with two small case series describing a spec...

Trajectories of Neurologic Recovery 12 Months After Hospitalization for COVID-19: A Pro...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9259089
Neurology Frontera JA, Yang D et. al.

Mar 23rd, 2022 - Little is known about trajectories of recovery 12 months after hospitalization for severe COVID-19. We conducted a prospective, longitudinal cohort study of patients with and without neurologic complications during index hospitalization for COVID-19 from March 10, 2020, to May 20, 2020. Phone follow-up batteries were performed at 6 and 12 months after COVID-19 onset. The primary 12-month outcom...

Neurologic Complications Rare After COVID-19 Vaccines
https://www.medpagetoday.com/neurology/generalneurology/97590

Mar 9th, 2022 - Neurologic adverse events after COVID-19 vaccination were rare, an analysis of Vaccine Adverse Event Reporting System (VAERS) data showed. Of nearly 307 million COVID vaccine doses administered in the U.S. in the first half of 2021, 314,610 (0.1%) people reported any adverse event and 105,214 (0.03%) reported neurologic adverse events, according to Jennifer Frontera, MD, of New York University ...

Acute transverse myelitis progressing to permanent quadriplegia following COVID-19 infe...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8864811
The American Journal of Emergency Medicine; Prete S, McShannic JD et. al.

Mar 7th, 2022 - As of January 2022, there have been over 350 million confirmed cases of COVID-19 in the world. The most common symptoms in those infected are fever, cough, malaise, and myalgia, however pulmonary, hematologic, gastrointestinal, renal, and neurologic complications have also been reported. Acute transverse myelitis (ATM) is an uncommon neurological syndrome characterized by acute or subacute spin...

New-Onset Ocular Myasthenia after Multisystem Inflammatory Syndrome in Children.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8882031
The Journal of Pediatrics; Yavuz P, Demir OO et. al.

Mar 2nd, 2022 - Neurologic complications have been associated with multisystem inflammatory syndrome in children, possibly involving autoimmune mechanisms. Here, we report a 6-year-old girl who developed myasthenia 11 weeks after severe acute respiratory syndrome coronavirus 2 infection and 8 weeks after the onset of severe multisystem inflammatory syndrome in children.

COVID-Related MIS-C May Be More Common Sequela Than Thought
https://www.medscape.com/viewarticle/968952

Feb 23rd, 2022 - NEW YORK (Reuters Health) - Multisystem inflammatory syndrome in children (MIS-C) may not be as rare a consequence of COVID-19 as previously thought. A cross-sectional study of U.S. children aged 5 to 11 years from 11 states suggests that there was roughly one MIS-C hospitalization for every COVID-19 hospitalization without MIS-C in the winter of 2020-2021. There were 379 MIS-C hospitalizations...

Delirium severity in critical patients with COVID-19 from an Infectious Disease Intensi...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8857775
International Journal of Infectious Diseases : IJID : Off... Dias R, Caldas JP et. al.

Feb 23rd, 2022 - COVID-19 is mainly characterized by respiratory manifestations. Nevertheless, neurologic complications have been described, including delirium, which appears to be frequent, prolonged, and severe. We conducted a retrospective analysis of demographic, clinical, and laboratory data of two cohorts: patients with COVID-19 admitted to the infectious disease intensive care unit (ID-ICU) and patients ...

Vision Loss Secondary to COVID-19 Associated Bilateral Cerebral Venous Sinus Thromboses.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9093223
Ophthalmic Plastic and Reconstructive Surgery; Omari A, Kally P et. al.

Feb 17th, 2022 - A young, morbidly obese woman with recent SARS-CoV-2 infection requiring hospitalization presented with visual and neurologic complications secondary to bilateral cerebral venous sinus thromboses. With elevated intracranial pressure and severe papilledema, she rapidly progressed to complete bilateral vision loss despite anticoagulation, therapeutic lumbar punctures with lumbar drain, bilateral ...

Unlocking the Key to COVID-19 and the Brain
https://www.medpagetoday.com/neurology/generalneurology/96803

Jan 21st, 2022 - How can a respiratory pathogen like SARS-CoV-2 cause the nervous system to go haywire? That's a question yet to be answered, observed Serena Spudich, MD, MA, of Yale University, and Avindra Nath, MD, of the National Institute of Neurological Disorders and Stroke, in an essay in Science. "Though COVID-19 is well known as a respiratory disease, neurological symptoms such as confusion, strokes, he...

Nervous system consequences of COVID-19
https://www.science.org/doi/10.1126/science.abm2052
Science Spudich S, Nath A.

Jan 20th, 2022 - Although severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is considered a respiratory pathogen, myriad neurologic complications—including confusion, stroke, and neuromuscular disorders—manifest during acute COVID-19. Furthermore, maladies such as impaired concentration, headache, sensory disturbances, depression, and even psychosis may persist for months after infection, as part of ...

Peripheral neurological complications during COVID-19: A single center experience.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8697415
Journal of the Neurological Sciences; Michaelson NM, Malhotra A et. al.

Jan 1st, 2022 - We highlight the peripheral neurologic complications of coronavirus disease 2019 (COVID-19) associated with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), an ongoing global health emergency. We evaluated twenty-five patients admitted to the COVID-19 Recovery Unit (CRU) at New York-Presbyterian Weill Cornell University Medical Center after intensive care hospitalization with confi...

Hypercoagulability of COVID-19 and Neurological Complications: A Review.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8547944
Journal of Stroke and Cerebrovascular Diseases : the Offi... Moore P, Esmail F et. al.

Nov 12th, 2021 - The SARS-CoV-2 virus, which causes Coronavirus disease 2019 (COVID-19), has resulted in millions of worldwide deaths. When the SARS-CoV-2 virus emerged from Wuhan, China in December 2019, reports of patients with COVID-19 revealed that hospitalized patients had acute changes in mental status, cognition, and encephalopathy. Neurologic complications can be a consequence from overall severity of t...

Rare Neurologic Events More Common After COVID Infection Than After Vaccine
https://www.medpagetoday.com/neurology/generalneurology/95276

Oct 26th, 2021 - Risk of neurologic complications was higher after SARS-CoV-2 infection than after COVID-19 vaccination, an analysis of 32 million people in England showed. Observed neurologic events associated with the Oxford-AstraZeneca and Pfizer-BioNTech (Comirnaty) vaccines were rare and risks after COVID infection was much greater, reported Julia Hippisley-Cox, MBChB, MD, of the University of Oxford, and ...

Neurologic Manifestations of Severe Acute Respiratory Syndrome Coronavirus 2 Infection.
https://doi.org/10.1212/CON.0000000000000992
Continuum (Minneapolis, Minn.); Nath A

Oct 9th, 2021 - This article describes the spectrum of neurologic complications associated with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, their underlying pathology and pathogenic mechanisms, gaps in knowledge, and current therapeutic strategies. COVID-19 is the clinical syndrome caused by the novel coronavirus SARS-CoV-2. It can affect the entire neuraxis, and presentations in th...

A unique case of Miller Fisher-Guillain-Barré overlap syndrome in a liver transplant re...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8456682
Journal of Neurovirology; Ramirez-Sanchez C, Syed R et. al.

Sep 23rd, 2021 - Guillain-Barré syndrome (GBS) is an ascending demyelinating polyneuropathy often associated with recent infection. Miller Fisher syndrome represents a variant with predominant facial and cranial nerve involvement, although Miller Fisher and Guillain-Barré overlap syndromes can occur. Guillain-Barré spectrum syndromes have been thought to be rare among solid organ transplant recipients. We descr...

Allergic reactions and adverse events associated with administration of mRNA-based vacc...
https://doi.org/10.2500/aap.2021.42.210069
Allergy and Asthma Proceedings; Arroliga ME, Dhanani K et. al.

Sep 4th, 2021 - Background: Adverse reactions, including anaphylaxis, to messenger RNA coronavirus disease 2019 (COVID-19) vaccines rarely occur. Because of the need to administer a timely second dose in subjects who reported a reaction to their first dose, a panel of health-care professionals developed a safe triage of the employees and health care providers (EHCP) at a large health-care system to consider ad...