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Peripheral neurological complications during COVID-19: A single center experience.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8697415
Journal of the Neurological Sciences; Michaelson NM, Malhotra A et. al.

Jan 1st, 2022 - We highlight the peripheral neurologic complications of coronavirus disease 2019 (COVID-19) associated with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), an ongoing global health emergency. We evaluated twenty-five patients admitted to the COVID-19 Recovery Unit (CRU) at New York-Presbyterian Weill Cornell University Medical Center after intensive care hospitalization with confi...

Hypercoagulability of COVID-19 and Neurological Complications: A Review.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8547944
Journal of Stroke and Cerebrovascular Diseases : the Offi... Moore P, Esmail F et. al.

Nov 12th, 2021 - The SARS-CoV-2 virus, which causes Coronavirus disease 2019 (COVID-19), has resulted in millions of worldwide deaths. When the SARS-CoV-2 virus emerged from Wuhan, China in December 2019, reports of patients with COVID-19 revealed that hospitalized patients had acute changes in mental status, cognition, and encephalopathy. Neurologic complications can be a consequence from overall severity of t...

Rare Neurologic Events More Common After COVID Infection Than After Vaccine
https://www.medpagetoday.com/neurology/generalneurology/95276

Oct 26th, 2021 - Risk of neurologic complications was higher after SARS-CoV-2 infection than after COVID-19 vaccination, an analysis of 32 million people in England showed. Observed neurologic events associated with the Oxford-AstraZeneca and Pfizer-BioNTech (Comirnaty) vaccines were rare and risks after COVID infection was much greater, reported Julia Hippisley-Cox, MBChB, MD, of the University of Oxford, and ...

Neurologic Manifestations of Severe Acute Respiratory Syndrome Coronavirus 2 Infection.
https://doi.org/10.1212/CON.0000000000000992 10.1159/000453066 10.1056/NEJMoa2002032 10.1016/j.jinf.2020.02.018 10.1016/j.ijid.2020.04.086 10.1212/WNL.0000000000010979 10.1007/s00405-020-05965-1 10.1016/j.cmi.2020.05.017 10.1126/sciadv.abc5801 10.1212/WNL.0000000000010806 10.1212/WNL.0000000000009850 10.1002/acn3.51210 10.1148/radiol.2020202040 10.1186/s13054-020-03200-1 10.1016/j.ijid.2020.03.062 10.1016/j.bbi.2020.05.012 10.1111/epi.16612 10.1111/bpa.12889 10.1056/NEJMc2019373 10.1111/nan.12662 10.1016/S1474-4422(20)30308-2 10.1016/j.jneuroim.2020.577326 10.1148/radiol.2020201187 10.1212/NXI.0000000000000789 10.12659/AJCR.925641 10.1212/WNL.0000000000010250 10.1111/ene.14491 10.1007/s00415-020-09951-9 10.1093/brain/awaa240 10.1101/2020.04.16.20068148 10.1212/NXI.0000000000000797 10.4103/0028-3886.299174 10.1590/0004-282X20200186 10.1136/bcr-2020-239597 10.1007/s00401-020-02166-2 10.2217/fca-2020-0082 10.1590/0004-282X20190162 10.1056/NEJMc2033369 10.1128/JVI.00404-18 10.1136/svn-2020-000431 10.1056/NEJMcp2009575 10.1016/j.jstrokecerebrovasdis.2020.105434 10.1212/WNL.0000000000010537 10.1161/STROKEAHA.120.030940 10.1101/2020.07.21.20159376 10.1177/1971400921988925 10.3389/fneur.2020.610648 10.1111/jth.14849 10.1007/s00059-020-04909-z 10.1093/eurheartj/ehaa288 10.1016/j.jstrokecerebrovasdis.2020.105016 10.1126/scitranslmed.abd3876 10.1016/j.tins.2020.10.009 10.1016/j.bbi.2020.07.007 10.1007/s13760-020-01497-x 10.1007/s00415-020-09934-w 10.1007/s00415-020-09997-9 10.1016/j.pediatrneurol.2020.07.017 10.1007/s00415-020-10145-6 10.1259/bjrcr.20200098 10.1056/NEJMc2009191 10.1007/s00415-020-10124-x 10.1212/WNL.0000000000009700 10.1212/WNL.0000000000009619 10.1002/mus.27003 10.3174/ajnr.A6711 10.1002/mus.27105 10.3201/eid2607.200445 10.7759/cureus.10686 10.1212/WNL.0000000000010640 10.1136/thoraxjnl-2020-215818 10.1111/andr.12839 10.1007/s15010-020-01524-2 10.3855/jidc.13224 10.1002/jmv.26169 10.1038/s41586-021-03207-w 10.1001/jamaneurol.2020.2687 10.1002/ana.26065 10.1038/d41586-020-02706-6 10.1001/jama.2021.7517 10.1056/NEJMoa2105385 10.1212/WNL.0000000000009520
Continuum (Minneapolis, Minn.); Nath A

Oct 9th, 2021 - This article describes the spectrum of neurologic complications associated with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, their underlying pathology and pathogenic mechanisms, gaps in knowledge, and current therapeutic strategies. COVID-19 is the clinical syndrome caused by the novel coronavirus SARS-CoV-2. It can affect the entire neuraxis, and presentations in th...

A unique case of Miller Fisher-Guillain-Barré overlap syndrome in a liver transplant re...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8456682
Journal of Neurovirology; Ramirez-Sanchez C, Syed R et. al.

Sep 23rd, 2021 - Guillain-Barré syndrome (GBS) is an ascending demyelinating polyneuropathy often associated with recent infection. Miller Fisher syndrome represents a variant with predominant facial and cranial nerve involvement, although Miller Fisher and Guillain-Barré overlap syndromes can occur. Guillain-Barré spectrum syndromes have been thought to be rare among solid organ transplant recipients. We descr...

Allergic reactions and adverse events associated with administration of mRNA-based vacc...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8677490
Allergy and Asthma Proceedings; Arroliga ME, Dhanani K et. al.

Sep 4th, 2021 - Background: Adverse reactions, including anaphylaxis, to messenger RNA coronavirus disease 2019 (COVID-19) vaccines rarely occur. Because of the need to administer a timely second dose in subjects who reported a reaction to their first dose, a panel of health-care professionals developed a safe triage of the employees and health care providers (EHCP) at a large health-care system to consider ad...

Can Guillain-Barré Syndrome Recur After mRNA COVID Vaccine?
https://www.medpagetoday.com/neurology/generalneurology/94331

Sep 2nd, 2021 - Serious relapse of Guillain-Barré syndrome (GBS) after receiving the Pfizer/BioNtech COVID-19 mRNA vaccine (Comirnaty) was rare, an analysis of medical records in Israel showed. Out of nearly 600 people previously diagnosed with GBS who got the vaccine, one needed brief medical care for relapse afterward, reported Shirley Shapiro Ben David, MD, of Maccabi Healthcare Services in Tel Aviv, and co...

Neurologic Manifestations and Complications of COVID-19.
https://doi.org/10.1146/annurev-med-042320-010427
Annual Review of Medicine; Hensley MK, Markantone D et. al.

Aug 21st, 2021 - Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has created a global pandemic. Beyond the well-described respiratory manifestations, SARS-CoV-2 may cause a variety of neurologic complications, including headaches, alteration in taste and smell, encephalopathy, cerebrovascular disease, myopathy, psychiatric diseases, and ocular disorders. Herein we describe SARS-CoV-2's mechanism of...

AAN Issues Formal Position Statement on COVID-19 Vaccine
https://www.medpagetoday.com/neurology/generalneurology/93862

Aug 2nd, 2021 - Based on existing evidence, neurologists should recommend COVID-19 vaccination to their patients, a newly released American Academy of Neurology (AAN) paper said. "Barring the rare circumstance of an absolute contraindication to available vaccine formulations, it is the American Academy of Neurology's formal position that eligible patients should be offered the COVID-19 vaccine," wrote Elisabet...

COVID-19 Tied to Acceleration of Alzheimer's Pathology
https://www.medscape.com/viewarticle/955755

Jul 30th, 2021 - Editor's note: Find the latest COVID-19 news and guidance in Medscape's Coronavirus Resource Center. DENVER ― Certain plasma biomarkers of neuronal damage and neuroinflammation are markedly elevated in hospitalized COVID-19 patients with neurologic symptoms compared to hospitalized COVID-19 patients without such symptoms, a new study shows. These results suggest COVID-19 may accelerate Alzheime...

SARS-CoV-2 Neuronal Invasion and Complications: Potential Mechanisms and Therapeutic Ap...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8221594
The Journal of Neuroscience : the Official Journal of The... Swain O, Romano SK et. al.

Jun 25th, 2021 - Clinical reports suggest that the coronavirus disease-19 (COVID-19) pandemic caused by severe acute respiratory syndrome (SARS)-coronavirus-2 (CoV-2) has not only taken millions of lives, but has also created a major crisis of neurologic complications that persist even after recovery from the disease. Autopsies of patients confirm the presence of the coronaviruses in the CNS, especially in the ...

Cochlear implantation for single-sided deafness after COVID-19 hospitalization.
https://doi.org/10.1080/14670100.2021.1936364
Cochlear Implants International; Asfour L, Kay-Rivest E et. al.

Jun 22nd, 2021 - Understanding the clinical manifestations of the coronavirus disease (COVID-19) has become an urgent objective in the research community. Amongst the emerging neurologic complications is sensorineural hearing loss. While several cases of hearing loss amongst COVID-19 patients have been reported, the management of these patients has yet to be discussed and determined. Herein we present cochlear ...

Understanding the Role of Blood Vessels in the Neurologic Manifestations of Coronavirus...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8193973
The American Journal of Pathology; Whitmore HAB, Kim LA

Jun 15th, 2021 - Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was originally identified as an outbreak in Wuhan, China, toward the end of 2019 and quickly became a global pandemic, with a large death toll. Originally identified as a respiratory disease, similar to previously discovered SARS and Middle East respiratory syndrome (MERS), concern has since been raised about the effects of SARS-CoV-2...

CROI 2021: Neurologic Complications of HIV-1 Infection or COVID-19.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8224246
Topics in Antiviral Medicine; Ances BM, Anderson AM et. al.

Jun 10th, 2021 - The 2021 Conference on Retroviruses and Opportunistic Infections (CROI) featured a timely review of the neurologic complications of COVID-19 as well as new research findings on mechanisms by which SARS-CoV-2 may affect the brain. CROI included new and important findings about the neurologic complications of HIV-1, human polyomavirus 2 (also known as JC Virus), and cryptococcus. New long-term an...

Dementia Diagnosis and Suicide; Head Injury Disability; Complexity of Chronic Pain
https://www.medpagetoday.com/neurology/generalneurology/92857

Jun 1st, 2021 - Death by suicide increased after Alzheimer's or dementia diagnosis, with the highest risk among people 65 to 74 years old and in the first 90 days after diagnosis. (Alzheimer's and Dementia) Cholesterol catabolism and bile acid synthesis may have sex-specific effects on dementia progression. (PLOS Medicine) Blood oxygenation and neurovascular coupling were decreased in the hippocampus compared ...

Postinfectious Neurologic Complications in COVID-19: A Complex Case Report.
https://doi.org/10.2967/jnumed.120.256099
Journal of Nuclear Medicine : Official Publication, Socie... Tiraboschi P, Xhani R et. al.

May 22nd, 2021 - A 40-y-old woman with severe acute respiratory syndrome coronavirus 2 infection developed neurologic manifestations (confusion, agitation, seizures, dyskinesias, and parkinsonism) a few weeks after the onset of severe acute respiratory syndrome. MRI and cerebrospinal fluid analyses were unremarkable, but 18F-FDG PET/CT showed limbic and extralimbic hypermetabolism. A full recovery, alongside 18...

First Report of SARS-CoV-2 Detection in Cerebrospinal Fluid in a Child With Guillain-Ba...
https://doi.org/10.1097/INF.0000000000003146 10.1542/peds.2020-015115 10.1093/tropej/fmaa044
The Pediatric Infectious Disease Journal; Araújo NM, Ferreira LC et. al.

May 16th, 2021 - Underlying mechanisms on the association between severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and neurologic complications are still poorly understood. Cases of Guillain-Barré Syndrome (GBS) have been linked to the SARS-CoV-2 infection as the result of dysregulated immune response with damage in neuronal tissues. In the current report, we present the first pediatric ca...

Neurologic Complications in Hospitalized COVID Patients Common, Deadly
https://www.medscape.com/viewarticle/950937

May 11th, 2021 - Eight in 10 patients hospitalized with COVID-19 develop neurologic complications, and these patients are much more likely to die in hospital compared with their counterparts without neurologic complications, a global study shows. Findings from the Global Consortium Study of Neurologic Dysfunction in COVID-19 (GCS-NeuroCOVID) reveal 82% of hospitalized COVID-19 patients had neurologic manifestat...

COVID-19 as a Cause of Acute Neonatal Encephalitis and Cerebral Cytotoxic Edema.
https://doi.org/10.1097/INF.0000000000003145
The Pediatric Infectious Disease Journal; Fragoso DC, Marx C et. al.

Apr 27th, 2021 - The majority of coronavirus disease 2019 (COVID-19) have been confirmed in adults, with only a few reported cases in children. In the pediatric population, COVID-19 infection appears to be often unremarkable or associated with mild respiratory symptoms. Little is known about neurologic complications related to COVID-19 in newborns. We present a case of severe encephalitis with cytotoxic brain e...

Neurologic Emergencies during the Coronavirus Disease 2019 Pandemic.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7995638
Neurologic Clinics; Shulman JG, Ford T et. al.

Apr 27th, 2021 - Although minor neurologic complications of coronavirus disease 2019 are common, life-threatening neurologic emergencies are rare. Acute ischemic stroke, intracerebral hemorrhage, venous sinus thrombosis, seizures, and posterior reversible encephalopathy syndrome have been described. Hospitals have seen significant changes in the volume of patients presenting with neurologic emergencies. We revi...