×
Origin of new emergent Coronavirus and Candida fungal diseases-Terrestrial or cosmic?
https://doi.org/10.1016/bs.adgen.2020.04.002
Advances in Genetics; Steele EJ, Gorczynski RM et. al.

Oct 21st, 2020 - The origins and global spread of two recent, yet quite different, pandemic diseases is discussed and reviewed in depth: Candida auris, a eukaryotic fungal disease, and COVID-19 (SARS-CoV-2), a positive strand RNA viral respiratory disease. Both these diseases display highly distinctive patterns of sudden emergence and global spread, which are not easy to understand by conventional epidemiologic...

A systematic review of etiology, epidemiology, clinical manifestations, image findings,...
https://doi.org/10.1097/MD.0000000000022688
Medicine Xu J, Ma XP et. al.

Oct 21st, 2020 - Unknown origin pneumonia has been furiously spreading since the late of December 2019, subsequently spread to approximately all provinces and areas in China and many countries, which was announced as a Public Health Emergency of International Concern by World Health Organization (WHO). The studies on 2019 Corona Virus Disease-19 (COVID-19) conducted from various fields around the world. Herein,...

Factors Associated With US Adults' Likelihood of Accepting COVID-19 Vaccination.
https://doi.org/10.1001/jamanetworkopen.2020.25594
JAMA Network Open; Kreps S, Prasad S et. al.

Oct 20th, 2020 - The development of a coronavirus disease 2019 (COVID-19) vaccine has progressed at unprecedented speed. Widespread public uptake of the vaccine is crucial to stem the pandemic. To examine the factors associated with survey participants' self-reported likelihood of selecting and receiving a hypothetical COVID-19 vaccine. A survey study of a nonprobability convenience sample of 2000 recruited par...

COVID-19 vaccine hesitancy is associated with beliefs on the origin of the novel corona...
https://doi.org/10.1017/S0033291720004067
Psychological Medicine; Salali GD, Uysal MS

Oct 19th, 2020 - COVID-19 vaccine hesitancy is associated with beliefs on the origin of the novel coronavirus in the UK and Turkey.|2020|Salali GD,Uysal MS,|

COVID-19 vaccine trials: Duty of care and standard of prevention considerations.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7572645
Vaccine Singh JA

Oct 18th, 2020 - Multiple studies have identified transcriptome subtypes of high-grade serous ovarian carcinoma (HGSOC), but their interpretation and translation are complicated by tumor evolution and polyclonality accompanied by extensive accumulation of somatic aberrations, varying cell type admixtures, and different tissues of origin. In this study, we examined the chronology of HGSOC subtype evolution in th...

Mobile device data reveal the dynamics in a positive relationship between human mobilit...
https://doi.org/10.1073/pnas.2010836117
Proceedings of the National Academy of Sciences of the United States of America; Xiong C, Hu S et. al.

Oct 16th, 2020 - Accurately estimating human mobility and gauging its relationship with virus transmission is critical for the control of COVID-19 spreading. Using mobile device location data of over 100 million monthly active samples, we compute origin-destination travel demand and aggregate mobility inflow at each US county from March 1 to June 9, 2020. Then, we quantify the change of mobility inflow across t...

Grief Before and During the COVID-19 Pandemic: Multiple Group Comparisons.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7553097
Journal of Pain and Symptom Management; Eisma MC, Tamminga A

Oct 16th, 2020 - The author's method of oligomer sums for analysis of oligomer compositions of eukaryotic and prokaryotic genomes is described. The use of this method revealed the existence of general rules for the cooperative oligomeric organization of a wide list of genomes. These rules are called hyperbolic because they are associated with hyperbolic sequences including the harmonic progression 1, 1/2, 1/3, ...

Update of the current knowledge on genetics, evolution, immunopathogenesis, and transmi...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7545713
International Journal of Biological Sciences; Tizaoui K, Zidi I et. al.

Oct 16th, 2020 - In December 2019, an acute respiratory disease caused by novel species of coronavirus (SARS-CoV-2), emerged in China and has spread throughout the world. On 11th March 2020, the World Health Organization (WHO) officially declared coronavirus disease 19 (COVID-19) a pandemic, severe coronavirus-mediated human disease. Based on genomic and phylogenetic studies, SARS-CoV-2 might originate from bat...

COVID-19: discovery, diagnostics and drug development.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7543767
Journal of Hepatology; Asselah T, Durantel D et. al.

Oct 10th, 2020 - An epidemic of acute respiratory syndrome (Covid-19) started in humans in Wuhan in 2019, and became a pandemic. Groups from China Identified and sequenced the virus responsible for COVID-19, named SARS-CoV-2, and determined that it was a novel coronavirus (CoV) that shared high sequence identity with bat- and pangolin-derived SARS-like CoVs, suggesting a zoonotic origin. SARS-CoV-2 is a member ...

Extracellular vesicles: new players in regulating vascular barrier function.
https://doi.org/10.1152/ajpheart.00579.2020
American Journal of Physiology. Heart and Circulatory Physiology; Chatterjee V, Yang X et. al.

Oct 9th, 2020 - Extracellular vesicles (EVs) have attracted rising interests in the cardiovascular field not only because they serve as serological markers for circulatory disorders, but also because they participate in important physiological responses to stress and inflammation. In the circulation, these membranous vesicles are mainly derived from blood or vascular cells, and they carry cargos with distinct ...

First COVID-19 Case in Zambia - Comparative phylogenomic analyses of SARS-CoV-2 detecte...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7537667
International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases; Simulundu E, Mupeta F et. al.

Oct 9th, 2020 - Since its first discovery in December 2019 in Wuhan, China, COVID-19, caused by the novel coronavirus SARS-CoV-2, has spread rapidly worldwide. Whilst African countries were relatively spared initially, the initial low incidence of COVID-19 cases was not sustained for long due to continuing travel links between China, Europe and Africa.. In preparation, Zambia had applied a multisectoral nation...

Sexually Transmitted Diseases in the COVID-19 Era.
https://www.ncbi.nlm.nih.gov/pubmed/33032683
Skinmed Wiggins CJ, Rosen T

Oct 9th, 2020 - Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is an infectious disease of recent origin with high transmissibility and mortality. The resulting COVID-19 pandemic has impacted the United States the most, in terms of the number of confirmed cases and fatalities. How other aspects of public health will be impacted by this disease has yet to be fully realized. Sexually transmitted di...

Towards integrated surveillance-response systems for the prevention of future pandemics.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7539270
Infectious Diseases of Poverty; Zinsstag J, Utzinger J et. al.

Oct 8th, 2020 - Most human pathogens originate from non-human hosts and certain pathogens persist in animal reservoirs. The transmission of such pathogens to humans may lead to self-sustaining chains of transmission. These pathogens represent the highest risk for future pandemics. For their prevention, the transmission over the species barrier - although rare - should, by all means, be avoided. In the current ...

Covid-19, SARS -CoV-2, Origin, transmission and treatment aspects, a brief review.
https://doi.org/10.2174/1871526520666201006163641
Infectious Disorders Drug Targets; Nawaz S

Oct 7th, 2020 - The emergence of severe acute respiratory syndrome (SARS) in Wuhan (china) named as corona virus disease 19(covid-19) caused by the novel corona virus SARS-CoV-2 has caused hundreds of thousands of mortalities across the world ,while the mortality rate is in millions, leading it to be declared as a global pandemic. Numerous research activities are undergoing to reveal the disease and etiologica...

Characteristics of SARS-CoV-2 and COVID-19.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7537588
Nature Reviews. Microbiology; Hu B, Guo H et. al.

Oct 7th, 2020 - Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a highly transmissible and pathogenic coronavirus that emerged in late 2019 and has caused a pandemic of acute respiratory disease, named 'coronavirus disease 2019' (COVID-19), which threatens human health and public safety. In this Review, we describe the basic virology of SARS-CoV-2, including genomic characteristics and receptor...

Escherichia coli ST457: an emerging extended-spectrum β-lactam resistant lineage with r...
https://doi.org/10.1128/AAC.01118-20
Antimicrobial Agents and Chemotherapy; Nesporova K, Wyrsch ER et. al.

Oct 6th, 2020 - Silver gulls carry phylogenetically diverse Escherichia coli including globally dominant ExPEC sequence types and pandemic ExPEC-ST131 clades, however our large-scale study (504 samples) on silver gulls nesting off the coast of New South Wales identified E. coli ST457 as the most prevalent. A phylogenetic analysis of whole-genome sequences (WGS) of 138 ST457 comprising of 42 from gulls, two fro...

Peritoneal Dialysis Is an Option for Acute Kidney Injury Management in Patients with CO...
https://doi.org/10.1159/000511390
Blood Purification; Rodríguez-Chagolla JM, Vásquez Jiménez E et. al.

Oct 5th, 2020 - In December 2019, cases of acute respiratory illness of unknown origin were reported in Wuhan, China. The disease is caused by "severe acute respiratory syndrome coronavirus 2". After identifying severe lung damage, injury to other organs, such as the kidney, has been identified. Peritoneal dialysis is a renal replacement therapy (RRT) and is at least as effective as other extracorporeal therap...

Coronavirus pandemic highlights critical gaps in rural Internet access for migrant and ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7524630
Journal of the Medical Library Association : JMLA; Lee JGL, LePrevost CE et. al.

Oct 5th, 2020 - Migrant and seasonal farmworkers, who are essential workers in the coronavirus global public health emergency, face unique risks to their health as well as longstanding health inequities. This commentary highlights these risks and argues that Internet access represents an underappreciated but critical part of the public health response. The authors first discuss the unique risks farmworkers fac...

Microbial cell-free DNA in plasma of patients with sepsis: a potential diagnostic metho...
https://www.ncbi.nlm.nih.gov/pubmed/33002409
Discovery Medicine; Liao W, Zuo X et. al.

Oct 1st, 2020 - Sepsis is a life-threatening clinical condition demanding accurate and rapid diagnosis of the culprit pathogen, thereby to improve prognosis. Pathogen determination through blood culture is the gold standard for diagnosis but has limitations due to low sensitivity. Recently, circulating DNAs derived from pathogenic organisms were found in the plasma of patients with sepsis and were further prov...

Coronavirus hemagglutinin-esterase and spike proteins coevolve for functional balance a...
https://doi.org/10.1073/pnas.2006299117
Proceedings of the National Academy of Sciences of the United States of America; Lang Y, Li W et. al.

Sep 30th, 2020 - Human coronaviruses OC43 and HKU1 are respiratory pathogens of zoonotic origin that have gained worldwide distribution. OC43 apparently emerged from a bovine coronavirus (BCoV) spillover. All three viruses attach to 9-O-acetylated sialoglycans via spike protein S with hemagglutinin-esterase (HE) acting as a receptor-destroying enzyme. In BCoV, an HE lectin domain promotes esterase activity towa...