×
The COVID-19 epidemic of manuscripts.
https://doi.org/10.1111/jan.14437
Journal of Advanced Nursing; Watson R, Mark M

May 27th, 2020 - In the midst of the novel coronavirus pandemic-referred to as COVID-19-there has been much uncertainty. We remain uncertain about its precise origin, its structure and composition, how best to test for it, or for resulting immunity, whether or not exposure leads to immunity, whether or not disposable surgical masks are effective, why men and some ethnic minorities are more susceptible and just ...

Clinical features, isolation, and complete genome sequence of severe acute respiratory ...
https://doi.org/10.1002/jmv.26075
Journal of Medical Virology; Phan LT, Nguyen TV et. al.

May 27th, 2020 - In January 2020, we identified two SARS-CoV-2 infections in a familial cluster with one person coming from Wuhan, China. The complete genome sequences of two SARS-CoV-2 strains isolated from these patients were identical and 99.98% similar to strains isolated in Wuhan. This is genetically suggestive of human-to-human transmission of SARS-CoV-2 and indicates Wuhan as the most plausible origin of...

Emergency Preparedness: Where Did We Go Wrong With COVID-19?
https://www.medscape.com/viewarticle/931185

May 26th, 2020 - Find the latest COVID-19 news and guidance in Medscape's Coronavirus Resource Center. Our lack of preparation for the current pandemic was demonstrated by our failure to (1) recognize that the outbreak in China would seed the globe quickly and (2) rapidly distribute diagnostic tests. Shelter-in-place orders are a blunt instrument that was necessary to flatten the curve and slow down the outbrea...

COVID-19 May Cause Subacute Thyroiditis
https://www.medscape.com/viewarticle/931197

May 26th, 2020 - Editor's note: Find the latest COVID-19 news and guidance in Medscape's Coronavirus Resource Center. Coronavirus disease of 2019 (COVID-19) may lead to subacute thyroiditis in some patients, which is suspected to have viral or postviral origin, especially with upper respiratory tract infections, according to a case study in the Journal of Clinical Endocrinology & Metabolism. Alessandro Brancate...

Impact of the COVID-19 pandemic on patients suffering from musculoskeletal tumours.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7247966
International Orthopaedics; Thaler M, Khosravi I et. al.

May 26th, 2020 - The aim of the current study was to evaluate the impact of the coronavirus disease (COVID-19) pandemic on musculoskeletal tumor service by conducting an online survey of physicians. The survey was conducted among the members of the ISOLS (International Society of Limb Salvage) and the EMSOS (European Musculo-Skeletal Oncology Society). The survey consisted of 20 questions (single, multiple-resp...

Coronavirus disease (COVID-19): An updated review based on current knowledge and existi...
https://doi.org/10.1111/dth.13677
Dermatologic Therapy; Kaur I, Sharma A et. al.

May 24th, 2020 - The world entered the year 2020 with reports of the emergence of a new viral illness in Wuhan city, Hubei province, China. In January 2020, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was identified to be the causative novel coronavirus for the cluster of patients suffering from pneumonia in China. The disease was later named as coronavirus disease (COVID-19) and was declared a...

Psychological health during the coronavirus disease 2019 pandemic outbreak.
https://doi.org/10.1177/0020764020925835
The International Journal of Social Psychiatry; Mukhtar S

May 20th, 2020 - The current ongoing pandemic outbreak of COVID-19 (Coronavirus Disease 2019) has globally affected 213 countries and territories with more than 2.5 million confirmed cases and thousands of casualties. The unpredictable and uncertain COVID-19 outbreak has the potential of adversely affecting the psychological health on individual and community level. Currently all efforts are focused on the unde...

Subacute thyroiditis after SARS-CoV-2 infection.
https://doi.org/10.1210/clinem/dgaa276
The Journal of Clinical Endocrinology and Metabolism; Brancatella A, Ricci D et. al.

May 20th, 2020 - Subacute thyroiditis (SAT) is a thyroid disease of viral or post-viral origin. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that began in Wuhan, China, has spread rapidly worldwide and Italy has been severely affected by this outbreak. To report the first case of SAT related to SARS-CoV-2 infection. We describe the clinical, laboratory and imaging features of a 18 year old woman...

Chilblain-like Lesions Reported in Children Thought to Have COVID-19
https://www.medscape.com/viewarticle/930955

May 20th, 2020 - Editor's note: Find the latest COVID-19 news and guidance in Medscape's Coronavirus Resource Center. Two reports of chilblain-like lesions in children suspected of having COVID-19 in Spain and Italy have been published, joining other recent reports of such cases in the United States and elsewhere. These symptoms should be considered a sign of infection with the virus, but the symptoms themselve...

The Middle East Respiratory Syndrome Coronavirus (MERS-CoV) Outbreak at King Abdul-Aziz...
https://doi.org/10.1017/S1049023X20000709
Prehospital and Disaster Medicine; Alabdali A, Almakhalas K et. al.

May 19th, 2020 - Middle East Respiratory Syndrome Coronavirus (MERS-CoV) is a form of an infectious respiratory disease, discovered in November 2012 in Saudi Arabia. According to the World Health Organization (WHO; Geneva, Switzerland) reports, a total of 2,519 laboratory-confirmed cases and 866 MERS-CoV-related deaths were recorded as of March 5, 2016.1 The majority of reported cases originated from Saudi Arab...

GUESS WHO'S COMING TO DINNER: COVID-19 IN A COVID-FREE UNIT.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7233200
Urology Luciani LG, Mattevi D et. al.

May 19th, 2020 - To assess the impact of the pandemic on surgical activity and the occurrence and features of Covid-19 in a Covid-free urologic unit in a regional hospital in Northern Italy. Our Department is the only urologic service in the Trento Province, near Lombardy, the epicenter of Covid-19 in our Country. We reviewed the surgical and ward activities during the 4 weeks following the national lockdown (M...

A near full-length HIV-1 genome from 1966 recovered from formalin-fixed paraffin-embedd...
https://doi.org/10.1073/pnas.1913682117
Proceedings of the National Academy of Sciences of the United States of America; Gryseels S, Watts TD et. al.

May 18th, 2020 - With very little direct biological data of HIV-1 from before the 1980s, far-reaching evolutionary and epidemiological inferences regarding the long prediscovery phase of this pandemic are based on extrapolations by phylodynamic models of HIV-1 genomic sequences gathered mostly over recent decades. Here, using a very sensitive multiplex RT-PCR assay, we screened 1,645 formalin-fixed paraffin-emb...

WHO Chief Promises Review of Coronavirus Response, China Defends Its Performance
https://www.medscape.com/viewarticle/930673

May 18th, 2020 - GENEVA (Reuters) - The head of the World Health Organization said on Monday an independent evaluation of the global coronavirus response would be launched as soon as possible, and China backed such a review. Director-General Tedros Adhanom Ghebreyesus made his promise during a virtual meeting of the WHO's decision-making body, the World Health Assembly, at which Chinese President Xi Jinping def...

The need to manage the risk of thromboembolism in COVID-19 patients.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7224653
Journal of Vascular Surgery; Khan IH, Savarimuthu S et. al.

May 17th, 2020 - COVID-19 first presented in Wuhan, Hubei Province, China, in December 2019. Thought to be of zoonotic origin, it has been named SARS-CoV-2 (COVID-19) and has spread rapidly. As of April 20th, 2020, there have been more than 2.4 million cases recorded worldwide. The inflammatory process, cytokine storm, and lung injury that are associated with COVID-19 can put patients at an increased risk of th...

Fake Science: XMRV, COVID-19, and the Toxic Legacy of Dr. Judy Mikovits.
https://doi.org/10.1089/AID.2020.0095
AIDS Research and Human Retroviruses; Neil SJD, Campbell EM

May 17th, 2020 - One cannot spend >5 min on social media at the moment without finding a link to some conspiracy theory or other regarding the origin of SARS-CoV2, the coronavirus responsible for the COVID-19 pandemic. From the virus being deliberately released as a bioweapon to pharmaceutical companies blocking the trials of natural remedies to boost their dangerous drugs and vaccines, the Internet is rife wit...

Tracking the origin of early COVID-19 cases in Canada.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7231484
International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases; Zhao N, Liu Y et. al.

May 16th, 2020 - The original coronavirus disease (COVID-19) outbreak in Wuhan, China has become a global pandemic. By tracking the earliest 118 COVID-19 cases in Canada, we produced a Voronoi treemap to show the travel origins of the country's earliest COVID-19 cases. By March 11, 2020, even though the majority (64.1%) of the world's COVID-19 confirmed cases still had their origin in China, only 7.6% of Canada...

EU Top Diplomat Wants Independent Probe Into Coronavirus Origins
https://www.medscape.com/viewarticle/930568

May 15th, 2020 - BERLIN (Reuters) — The European Union's foreign policy chief called on China on Thursday to contribute significantly to the fight against the coronavirus pandemic and said there should be an independent scientific investigation into the origins of the pandemic. In a guest column in Friday's edition of the Frankfurter Allgemeine Zeitung newspaper, Josep Borrell said China should act to help prot...

Is the kidney a target of SARS-CoV-2?
https://doi.org/10.1152/ajprenal.00160.2020
American Journal of Physiology. Renal Physiology; Martínez-Rojas MA, Vega-Vega O et. al.

May 14th, 2020 - The new disease produced by the Severe Acute Respiratory Syndrome - coronavirus 2 (SARS-CoV-2) represents a major pandemic event nowadays. Since its origin in China in December 2019, there is compelling evidence that novel SARS-CoV-2 is a highly transmissible virus, and it is associated to a broad clinical spectrum going from subclinical presentation to severe respiratory distress and multi-org...

Comparison of SARS-CoV-2 spike protein binding to ACE2 receptors from human, pets, farm...
https://doi.org/10.1128/JVI.00831-20
Journal of Virology; Zhai X, Sun J et. al.

May 14th, 2020 - The emergence of a novel coronavirus, SARS-CoV-2, resulted in a pandemic. Here, we used X-ray structures of human ACE2 bound to the receptor-binding domain (RBD) of the spike protein (S) from SARS-CoV-2 to predict its binding to ACE2 proteins from different animals, including pets, farm animals, and putative intermediate hosts of SARS-CoV-2. Comparing the interaction sites of ACE2 proteins know...

Impact of international travel dynamics on domestic spread of 2019-nCoV in India: origi...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7216130
Globalization and Health; Gunthe SS, Patra SS

May 13th, 2020 - The recent pandemic caused by the 2019 outbreak of novel coronavirus (2019-nCoV or COVID-19) has affected more than 3.0 million people resulting ~ 212,000 deaths across 215 countries/territories as on 28th April 2020. The importation of the cases owing to enormous international travels from the affected countries is the foremost reason for local cycle of transmission. For a country like India, ...