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Can Family Medicine's Counterculture History Help Shape an Anti-Racist Future?
https://doi.org/10.3122/jabfm.2022.01.210295
Journal of the American Board of Family Medicine : JABFM; Sturges D, Patterson DG et. al.

Jan 19th, 2022 - Family medicine prides itself on community engagement and has embraced its counterculture roots. After the racial and social reckoning of 2020, including the COVID-19 pandemic and the Black Lives Matters movement, family medicine, as a specialty, must embrace anti-racism as a core value to meet community needs. This article reflects on the foundational tenets of family medicine's origin. It hig...

COVID-19 and the Otolaryngology Residency Match: Rising Incidence of Home Matches.
https://doi.org/10.1002/lary.30028
The Laryngoscope; Bernstein JD, Harmon M et. al.

Jan 18th, 2022 - To quantify the effect of the COVID-19 pandemic upon the 2020-21 residency match for Otolaryngology-Head & Neck Surgery (OHNS). Residency match outcomes for all applicants to our institution during 2020-2021 were collected from the National Residency Matching Program (NRMP) including medical school of origin and matched program. Matches were categorized as to home-program, within-region, or out...

The origin of SARS-CoV-2 variants of concern.
https://doi.org/10.1016/S1473-3099(22)00015-9
The Lancet. Infectious Diseases; Burki T

Jan 17th, 2022 - The origin of SARS-CoV-2 variants of concern.|2022|Burki T,|

The source of financial contagion and spillovers: An evaluation of the covid-19 pandemi...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8759666
PloS One; Gunay S, Can G

Jan 15th, 2022 - This study investigates the reaction of stock markets to the Covid-19 pandemic and the Global Financial Crisis of 2008 (GFC) and compares their influence in terms of risk exposures. The empirical investigation is conducted using the modified ICSS test, DCC-GARCH, and Diebold-Yilmaz connectedness analysis to examine financial contagion and volatility spillovers. To further reveal the impact of t...

Significant increase in astigmatism in children after study at home during the COVID-19...
https://doi.org/10.1080/08164622.2021.2024071
Clinical & Experimental Optometry; Liang Y, Leung TW et. al.

Jan 14th, 2022 - Evaluating changes in refractive astigmatism after 'study at home' during the COVID pandemic may shed light on the aetiology of refractive errors. To investigate whether there has been a change in the proportion of astigmatism among primary school children after the school closure period during the COVID-19 pandemic. This observational study compared cross-sectional (2018: n = 112; 2020: n = 17...

Self-limiting COVID-19-associated Kikuchi-Fujimoto disease with heart involvement: case...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8757403
Rheumatology International; Masiak A, Lass A et. al.

Jan 14th, 2022 - The association between COVID-19 infection and the development of autoimmune diseases is currently unknown, but there are already reports presenting induction of different autoantibodies by SARS-CoV-2 infection. Kikuchi-Fuimoto disease (KFD) as a form of histiocytic necrotizing lymphadenitis of unknown origin. Here we present a rare case of KFD with heart involvement after COVID-19 infection. T...

Diversity and evolution of the animal virome.
https://doi.org/10.1038/s41579-021-00665-x 10.1007/s00705-021-05156-1 10.21203/rs.3.rs-871965/v1 10.1111/tbed.14173 10.1101/2021.07.29.454326 10.1101/2020.08.07.241729 10.1002/0471142727.mb0419s103
Nature Reviews. Microbiology; Harvey E, Holmes EC

Jan 6th, 2022 - The COVID-19 pandemic has given the study of virus evolution and ecology new relevance. Although viruses were first identified more than a century ago, we likely know less about their diversity than that of any other biological entity. Most documented animal viruses have been sampled from just two phyla - the Chordata and the Arthropoda - with a strong bias towards viruses that infect humans or...

Review of authorship for COVID-19 research conducted during the 2020 first-wave epidemi...
https://doi.org/10.1111/tmi.13717
Tropical Medicine & International Health : TM & IH; Tonen-Wolyec S, Mbumba Lupaka DM et. al.

Jan 6th, 2022 - The contribution of African authors to the biomedical literature is small. We evaluated the African and non-African scientific production published in the international literature on the COVID-19 in Africa during the first year of the epidemic (2020). Papers on COVID-19 in Africa were extracted from the Medline (PubMed) database for bibliometric analysis including the proportions of three leadi...

Loncastuximab Tesirine/Ibrutinib Combination Elicits Encouraging Activity in Relapsed/Refractory DLBCL
https://www.onclive.com/view/loncastuximab-tesirine-ibrutinib-combination-elicits-encouraging-activity-in-relapsed-refractory-dlbcl

Jan 4th, 2022 - Treatment with ibrutinib (Imbruvica) plus loncastuximab tesirine-lpyl (Zynlonta) resulted in high objective and complete response (CR) rates and an acceptable safety profile in patients with relapsed/refractory (R/R) diffuse large B-cell lymphoma (DLBCL), according to findings from an interim analysis of the phase 1/2 LOTIS-3 trial (NCT03684694) that were presented at the 2021 ASH Annual Meetin...

Etesevimab - etesevimab injection, solution-Eli Lilly and Company
https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=aacdd8a7-18b7-43c6-b866-14aa491a0c15

Jan 4th, 2022 - SPL UNCLASSIFIED SECTION TREATMENT The U.S. Food and Drug Administration (FDA) has issued an Emergency Use Authorization (EUA) to permit the emergency use of the unapproved products bamlanivimab and etesevimab administered together for the treatment of mild to moderate coronavirus disease 2019 (COVID-19) in adults and pediatric patients, including neonates, with positive results of direct SARS-...

WHO's Tedros Concerned About 'Tsunami of Cases' From COVID-19 Variants
https://www.medscape.com/viewarticle/965735

Dec 30th, 2021 - GENEVA (Reuters) - The simultaneous circulation of the Delta and Omicron variants of the coronavirus is creating a "tsunami of cases", World Health Organization (WHO) director-general Tedros Adhanom Ghebreyesus told a news briefing on Wednesday. "Delta and Omicron are now twin threats driving up cases to record numbers, leading to spikes in hospitalisation and deaths," said Tedros. "I am highly...

COVID-19 Cases at Record High Around World, Raising Testing and Quarantine Fears
https://www.medscape.com/viewarticle/965734

Dec 30th, 2021 - (Reuters) - Global COVID-19 infections hit a record high over the past seven-day period, Reuters data showed on Wednesday, as the new Omicron variant raced out of control, keeping workers at home and overwhelming testing centres. Almost 900,000 cases were detected on average each day around the world between Dec. 22 and 28, with myriad countries posting new all-time highs over the past 24 hours...

Making sense of unfamiliar COVID-19 vaccines: How national origin affects vaccination w...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8716032
PloS One; Jensen EA, Wagoner B et. al.

Dec 30th, 2021 - Vaccination willingness is a critical factor in pandemics, including the COVID-19 crisis. Therefore, investigating underlying drivers of vaccination willingness/hesitancy is an essential social science contribution. The present study of German residents investigates the mental shortcuts people are using to make sense of unfamiliar vaccine options by examining vaccination willingness for differe...

Emergence in Southern France of a new SARS-CoV-2 variant of probably Cameroonian origin harbouring both substitutions N501Y and E484K in the spike protein
https://www.medrxiv.org/content/10.1101/2021.12.24.21268174v1.full
Medrxiv Colson P, .

Dec 29th, 2021 - SARS-CoV-2 variants have become a major virological, epidemiological and clinical concern, particularly with regard to the risk of escape from vaccine-induced immunity. Here we describe the emergence of a new variant. For twelve SARS-CoV-positive patients living in the same geographical area of southeastern France, qPCR testing that screen for variant-associated mutations showed an atypical com...

OMICRON (B.1.1.529): A new SARS-CoV-2 variant of concern mounting worldwide fear.
https://doi.org/10.1002/jmv.27541
Journal of Medical Virology; Thakur V, Ratho RK

Dec 23rd, 2021 - Recent emergence of the SARS-CoV-2 variant as OMICRON has become a global concern. This short note highlights the identification and global spread of OMICRON which has spread over 77 nations by now, which resulted in many hypotheses about its origin and degree of infectivity. The detection of mutations in the RBD region of Spike protein is a concern by surpassing vaccine immunity. The ahead wil...

Sotrovimab - sotrovimab injection, solution, concentrate-GlaxoSmithKline LLC
https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=aa5cca2e-4351-4f81-b0e5-3303ac0b2474

Dec 22nd, 2021 - SPL UNCLASSIFIED SECTION The U.S. Food and Drug Administration (FDA) has issued an Emergency Use Authorization (EUA) to permit the emergency use of the unapproved product sotrovimab for the treatment of mild-to-moderate coronavirus disease 2019 (COVID-19) in adults and pediatric patients (12 years of age and older weighing at least 40 kg) with positive results of direct SARS-CoV-2 viral testing...

Bamlanivimab - bamlanivimab injection, solution-Eli Lilly and Company
https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=c7e9d8a6-e8c2-4681-9362-51d5bdbae00d

Dec 22nd, 2021 - SPL UNCLASSIFIED SECTION TREATMENT The U.S. Food and Drug Administration (FDA) has issued an Emergency Use Authorization (EUA) to permit the emergency use of the unapproved products bamlanivimab and etesevimab administered together for the treatment of mild to moderate coronavirus disease 2019 (COVID-19) in adults and pediatric patients, including neonates, with positive results of direct SARS-...

Similar risk of SARS-CoV-2 infection and similar nucleocapsid antibody levels in people...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8755357
The Journal of Infectious Diseases; Verburgh ML, Boyd A et. al.

Dec 21st, 2021 - Within the ongoing AGEhIV Cohort Study in Amsterdam, we prospectively compared the incidence of and risk factors for SARS-CoV-2 infection between HIV-positive and -negative participants. Moreover, we compared SARS-CoV-2 nucleocapsid antibody levels between participants with incident infection from both groups. Starting in September 2020, consenting HIV-positive and HIV-negative participants wer...

Effective presence of antibodies against common human coronaviruses in immunoglobulin m...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8679496
International Journal of Infectious Diseases : IJID : Off... Díez JM, Romero C et. al.

Dec 21st, 2021 - Immunoglobulin products (for intravenous, intramuscular and subcutaneous administration) prepared from geographically diverse plasma pools were tested for activity against common human coronaviruses (HCoVs). Products from plasma obtained from Germany, Czech Republic, Slovak Republic, USA and Spain were tested for antibodies to common HCoVs: 229E, OC43, NL63 and HKU1. As these products are manuf...

Evusheld - azd7442 kit-AstraZeneca Pharmaceuticals LP
https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=168dad7e-9b75-4780-8c8c-34e164de0733

Dec 20th, 2021 - SPL UNCLASSIFIED SECTION HIGHLIGHTS OF EMERGENCY USE AUTHORIZATION (EUA) These highlights of the EUA do not include all the information needed to use EVUSHELD™ under the EUA. See the FULL FACT SHEET FOR HEALTHCARE PROVIDERS for EVUSHELD. EVUSHELD (tixagevimab) injection; (cilgavimab) injection, co-packaged for intramuscular use Original EUA Authorized Date: 12/2021 -------------EUA FOR EVUSHELD...