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Non-melanoma skin cancer diagnosis: a comparison between dermoscopic and smartphone ima...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8453469
Journal of Cancer Research and Clinical Oncology; Dascalu A, Walker BN et. al.

Sep 22nd, 2021 - Non-melanoma skin cancer (NMSC) is the most frequent keratinocyte-origin skin tumor. It is confirmed that dermoscopy of NMSC confers a diagnostic advantage as compared to visual face-to-face assessment. COVID-19 restrictions diagnostics by telemedicine photos, which are analogous to visual inspection, displaced part of in-person visits. This study evaluated by a dual convolutional neural networ...

Genetic Diversity of SARS-CoV-2 among Travelers Arriving in Hong Kong.
https://doi.org/10.3201/eid2710.211028
Emerging Infectious Diseases; Gu H, Chu DKW et. al.

Sep 22nd, 2021 - We sequenced 10% of imported severe acute respiratory syndrome coronavirus 2 infections detected in travelers to Hong Kong and revealed the genomic diversity of regions of origin, including lineages not previously reported from those countries. Our results suggest that international or regional travel hubs might be useful surveillance sites to monitor sequence diversity.

Low COVID-19 vaccine hesitancy in Brazil.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8421107
Vaccine Moore DCBC, Nehab MF et. al.

Sep 19th, 2021 - The COVID-19 pandemic has affected the entire world, and the vaccine has emerged as a source of hope for return to normal life. Still, various countries have reported high vaccine hesitancy rates. It is important to know the vaccine hesitancy profile in Brazil to help design adequate communication strategies. A voluntary, anonymous online survey was conducted from January 22 to 29, 2021, includ...

Risk prediction of covid-19 related death and hospital admission in adults after covid-...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8446717
BMJ (Clinical Research Ed.); Hippisley-Cox J, Coupland CA et. al.

Sep 19th, 2021 - To derive and validate risk prediction algorithms to estimate the risk of covid-19 related mortality and hospital admission in UK adults after one or two doses of covid-19 vaccination. Prospective, population based cohort study using the QResearch database linked to data on covid-19 vaccination, SARS-CoV-2 results, hospital admissions, systemic anticancer treatment, radiotherapy, and the nation...

A single dose of the Biontech/Pfizer BNT162b2 vaccine protected elderly residents from ...
https://doi.org/10.1002/iid3.532
Immunity, Inflammation and Disease; Schwarzer R, Freys SD et. al.

Sep 17th, 2021 - A total of 62/66 (93.9%) residents in a senior citizen home in Bremen, Germany, received the first dose of the Biontech/Pfizer vaccine BNT162b2 on December 27th 2020. After routine severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antigen tests showed positive results on January 5th, all residents and staff were tested by RT-PCR. Nine staff members and 23 residents had a positive res...

SARS-CoV-2's origin should be investigated worldwide for pandemic prevention
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(21)02020-1/fulltext
The Lancet; Wu Z, .

Sep 17th, 2021 - The origin of SARS-CoV-2 has received intensive global attention since its spread was first reported to the international community in early January, 2020. Multiple studies1, 2, 3, 4, 5, 6, 7, 8, 9 conducted collaboratively by scientists around the world have found that animal-to-human cross-species spillover is the most likely source of SARS-CoV-2, whereas laboratory leakage is extreme...

Gastrointestinal manifestations of coronavirus disease 2019.
https://doi.org/10.1097/QCO.0000000000000760 10.1016/s2666-5247(20)30003-3 10.1016/j.virusres.2020.198147 10.1098/rsob.200160 10.1126/sciadv.aao4966 10.1155/2019/3950628 10.1016/j.metabol.2020.154244
Current Opinion in Infectious Diseases; Joshi T, Ahmed A et. al.

Sep 16th, 2021 - The ubiquitous expression of angiotensin-converting enzyme-2 receptors and its significance as the origin of viral entry have assisted in comprehending the pathophysiology of extrapulmonary manifestations of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. In this review, we focus on the clinical significance of gastrointestinal manifestations. The global pandemic, a resu...

Attitudes of Chinese immigrants in Canada towards the use of Traditional Chinese Medici...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8441218
BMJ Open; Kong Y, Shaver LG et. al.

Sep 16th, 2021 - The objective of this study was to assess attitudes towards the use of Traditional Chinese Medicine (TCM) for COVID-19 among Chinese immigrants in Canada during the early stage of the COVID-19 pandemic. A cross-sectional study was conducted in April 2020 in Canada. Individuals aged 16 or older who were of Chinese origin and living in Canada at the time of the survey were invited to participate ...

The SARS-CoV-2 spike protein is vulnerable to moderate electric fields.
https://doi.org/10.1038/s41467-021-25478-7 10.1126/science.abb2507 10.1016/j.cell.2020.02.058 10.1038/s41586-020-2599-8 10.1186/s12967-020-02392-y 10.1080/22221751.2020.1729069 10.1016/j.intimp.2020.106560 10.3390/v12050526 10.1016/j.bcp.2020.114184 10.1007/s40475-020-00201-6 10.1016/j.apsb.2020.02.008 10.1111/bph.15092 10.1021/acs.jpclett.0c01431 10.1038/s41422-020-00430-4 10.1021/acsnano.0c04798 10.1021/acs.jpclett.0c01148 10.1126/science.abb9983 10.1073/pnas.1708727114 10.3390/v4061011 10.1038/s41586-020-2180-5 10.1016/j.chom.2020.06.010 10.1038/s41586-020-2772-0 10.1038/s41586-020-2571-7 10.1126/science.abc6952 10.1038/nature20571 10.3390/polym11020282 10.1016/j.bpj.2010.04.040 10.1039/C3SM52653D 10.1089/bioe.2019.0021 10.1021/jp052742q 10.1021/jp501051r 10.1021/jp309857b 10.1371/journal.pone.0221685 10.1039/D0CP03145C 10.1039/D0RA08222H 10.1016/j.bbrc.2003.08.122 10.1126/science.1116480 10.1016/j.cell.2020.09.032 10.1529/biophysj.106.092452 10.1016/S0166-2236(99)01534-9 10.1038/s41594-020-0479-4 10.1038/s41586-020-2895-3 10.1016/j.cell.2020.03.045 10.1021/acs.jpclett.0c01064 10.1073/pnas.2008209117 10.1038/s41598-020-71188-3 10.1128/JVI.00617-21 10.1021/acs.jpclett.0c02958 10.1371/journal.ppat.1007236 10.1002/prot.22922 10.1038/s41423-020-0458-z 10.1021/acsnano.0c04674 10.1016/j.pbiomolbio.2003.09.003 10.1016/0959-440X(95)80079-4 10.1002/jmr.577 10.1073/pnas.181342398 10.1093/nar/gkh381 10.1002/prot.21419 10.1136/bmj.m4857 10.1038/s41591-021-01378-7 10.1038/s41586-021-03402-9 10.1038/s41586-021-03398-2 10.1016/j.cell.2021.03.055 10.3390/biomedicines9050525 10.3390/v13030439 10.1016/j.cell.2020.08.012 10.1038/s41598-020-78711-6 10.1126/science.abb7269 10.1126/science.abd0826 10.1088/0963-0252/17/2/024010 10.1063/5.0037360 10.1016/j.cmet.2020.09.012 10.1126/science.abd3255 10.1007/s00134-020-05985-9 10.1021/jf072186s 10.1056/NEJMoa2108891 10.1016/j.chom.2021.02.003 10.3389/fimmu.2020.567710 10.1126/science.abe1107 10.1038/s41467-020-18450-4 10.1038/s41577-020-0389-z 10.1016/j.cell.2020.05.015 10.1039/C4CP02289K 10.1002/jcc.21287 10.1002/jcc.20945 10.1021/ct300400x 10.1002/jcc.20065 10.1002/(SICI)1096-987X(20000130)21:2<86::AID-JCC2>3.0.CO;2-G 10.1002/cpbi.3 10.1021/ct700301q 10.1093/bioinformatics/btt055 10.1016/j.softx.2015.06.001 10.1063/1.445869 10.1002/(SICI)1096-987X(199709)18:12<1463::AID-JCC4>3.0.CO;2-H 10.1021/ct700200b 10.1063/1.470117 10.1063/1.464397 10.1080/00268978300102851 10.1002/ange.200703987 10.1021/ct900576a 10.1021/ct400781b 10.1002/jcc.21787 10.1016/0263-7855(96)00018-5 10.1002/prot.20310 10.1063/1.2746330 10.1140/epjb/e2006-00353-0 10.1080/00268970210158632 10.1214/aos/1176344552 10.1021/acs.jctc.7b01014 10.1093/bioinformatics/btt262
Nature Communications; Arbeitman CR, Rojas P et. al.

Sep 15th, 2021 - Most of the ongoing projects aimed at the development of specific therapies and vaccines against COVID-19 use the SARS-CoV-2 spike (S) protein as the main target. The binding of the spike protein with the ACE2 receptor (ACE2) of the host cell constitutes the first and key step for virus entry. During this process, the receptor binding domain (RBD) of the S protein plays an essential role, since...

A strategy to assess spillover risk of bat SARS-related coronaviruses in Southeast Asia
https://www.medrxiv.org/content/10.1101/2021.09.09.21263359v1
Medrxiv Sánchez CA, .

Sep 14th, 2021 - Emerging diseases caused by coronaviruses of likely bat origin (e.g. SARS, MERS, SADS and COVID-19) have disrupted global health and economies for two decades. Evidence suggests that some bat SARS-related coronaviruses (SARSr-CoVs) could infect people directly, and that their spillover is more frequent than previously recognized. Each zoonotic spillover of a novel virus represents an opportu...

No Uptick in Vaccine Uptake; Unreported COVID Deaths; France Bans Unvaxxed Americans
https://www.medpagetoday.com/infectiousdisease/covid19/94444

Sep 10th, 2021 - Note that some links may require registration or subscription. The FDA's approval of the Pfizer/BioNTech COVID vaccine has yet to produce an expected uptick in vaccine uptake. (Business Insider) Four researchers whose work provided the basis for development of the first approved COVID-19 vaccine, along with a pioneer in the study of neurodegenerative diseases, are among the winners of the 2022 ...

SARS-CoV-2 infection in pregnancy during the first wave of COVID-19 in the Netherlands:...
https://doi.org/10.1111/1471-0528.16903
BJOG : an International Journal of Obstetrics and Gynaeco... Overtoom EM, Rosman AN et. al.

Sep 9th, 2021 - Describe characteristics, risk factors, maternal, obstetric and neonatal outcomes of SARS-CoV-2 infected pregnant women. Multi-centre prospective population-based cohort study. Nationwide study in the Netherlands. Pregnant women with confirmed SARS-CoV-2 infection admitted to hospital or in home-isolation: March 1st , 2020 - August 31st , 2020. Pregnant women with positive PCR or antibody tests...

Reflecting on the COVID-19 Surgical Literature Surge: A Scoping Review of Pandemic Otol...
https://doi.org/10.1177/01945998211041933
Otolaryngology--head and Neck Surgery : Official Journal ... von Sneidern M, Lehmann AE et. al.

Sep 8th, 2021 - To assess the high-volume 2020 COVID-19-related surgical literature, with special attention to otolaryngology articles in regard to content, level of evidence, citations, and public attention. A scoping literature review was performed with PubMed and Web of Science, including articles pertaining to COVID-19 and surgical specialties (March 20-May 19, 2020) or otolaryngologic subspecialties (Marc...

U.S. dog importations during the COVID-19 pandemic: Do we have an erupting problem?
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8423269
PloS One; Pieracci EG, Williams CE et. al.

Sep 8th, 2021 - Dog importation data from 2018-2020 were evaluated to ascertain whether the dog importation patterns in the United States changed during the COVID-19 pandemic, specifically with regard to denial of entry. Dog denial of entry reports from January 1, 2018, to December 31, 2020, stored within the Centers for Disease Control and Prevention (CDC) Quarantine Activity Reporting System (QARS), were rev...

Untangling Fact From Bias in the Age of Social Media and Mistrust
https://www.onclive.com/view/untangling-fact-from-bias-in-the-age-of-social-media-and-mistrust

Sep 2nd, 2021 - It is difficult to overstate the confusion—one might even use the term chaos— associated with our nation’s messaging regarding a well-considered, rational, and scientifically based public health–focused approach to the current and future ramifications of the COVID-19 pandemic. Concerns range from the effect of the delta variant on schools safely reopening for critical in-person learning,1,2 to...

COVID-19 disease in hospitalized young adults in India and China: Evaluation of risk fa...
https://doi.org/10.1002/jmv.27315
Journal of Medical Virology; Panda S, Roy S et. al.

Sep 2nd, 2021 - Data pertaining to risk factor analysis in coronavirus disease 2019 (COVID-19) is confounded by the lack of data from an ethnically diverse population. In addition, there is a lack of data for young adults. This study was conducted to assess risk factors predicting COVID-19 severity and mortality in hospitalized young adults. A retrospective observational study was conducted at two centers from...

A comparative study on virology, epidemiology, and clinical features of SARS and COVID-19.
https://doi.org/10.1017/dmp.2021.275
Disaster Medicine and Public Health Preparedness; Zhao Y, Lu Q et. al.

Sep 1st, 2021 - In December 2019, an outbreak of an unknown cause of pneumonia [later named coronavirus disease 2019 (COVID-19)] occurred in Wuhan, China. This was found to be attributed to a novel coronavirus of zoonotic origin, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2; previously named 2019 novel coronavirus or 2019-nCoV). The SARS-CoV-2, a new type of highly pathogenic human coronavirus r...

Origin of imported SARS-CoV-2 strains in The Gambia identified from whole genome sequen...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8407536
PloS One; Kanteh A, Manneh J et. al.

Sep 1st, 2021 - The SARS-CoV-2 disease, first detected in Wuhan, China, in December 2019 has become a global pandemic and is causing an unprecedented burden on health care systems and the economy globally. While the travel history of index cases may suggest the origin of infection, phylogenetic analysis of isolated strains from these cases and contacts will increase the understanding and link between local tra...

Psychological impact on COVID-19 patients during the outbreak in China: A case-control ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8381686
Psychiatry Research; Lu X, Xie Y et. al.

Aug 31st, 2021 - The coronavirus disease 2019 (COVID-19) has caused widespread panic due to its highly infectious and pandemic transmission. We aimed to evaluate the psychological impact of the COVID-19 outbreak on infected subjects in China. This case-control, survey-based study assessed the psychological status of COVID-19 patients and non-infected controls from February 10 to March 18, 2020, in China. Sex, a...

Inappropriately sweet: Environmental endocrine-disrupting chemicals and the diabetes pa...
https://doi.org/10.1016/bs.apha.2021.04.002
Advances in Pharmacology (San Diego, Calif.); Schulz MC, Sargis RM

Aug 29th, 2021 - Afflicting hundreds of millions of individuals globally, diabetes mellitus is a chronic disorder of energy metabolism characterized by hyperglycemia and other metabolic derangements that result in significant individual morbidity and mortality as well as substantial healthcare costs. Importantly, the impact of diabetes in the United States is not uniform across the population; rather, communiti...