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Pregnancy outcomes during the COVID-19 pandemic in Canada, March to August 2020.
https://doi.org/10.1016/j.jogc.2021.06.014
Journal of Obstetrics and Gynaecology Canada : JOGC = Jou... Liu S, Dzakpasu S et. al.

Aug 1st, 2021 - Several studies have documented changes in the rates preterm birth and stillbirth during the COVID-19 pandemic. We carried out a study to examine obstetric intervention, preterm birth, and stillbirth rates in Canada from March to August 2020. The study included all singleton hospital deliveries in Canada (excluding Québec) from March to August 2020 (and March to August for the years 2015-2019) ...

Cord blood antibody following maternal SARS-CoV-2 inactive vaccine (CoronaVac) administ...
https://doi.org/10.1080/21645515.2021.1947099
Human Vaccines & Immunotherapeutics; Soysal A, Bilazer C et. al.

Jul 31st, 2021 - Maternal vaccination with SARS-CoV-2 vaccines has not been well studied yet in terms of safety and efficacy for protecting the newborn by the placental passage of antibodies. We reported 34 years of old health care worker (HCW) without any known SARS-CoV-2 infection. She had the first dose of SARS-CoV-2 inactivated virus vaccine (CoronaVac, Sinovac Life Science Co, Ltd, Beijing, China) at a ges...

Endogenous control of inflammation characterizes pregnant women with asymptomatic or pa...
https://doi.org/10.1038/s41467-021-24940-w 10.1016/j.jri.2020.103122 10.15585/mmwr.mm6925a1 10.3390/v12020194 10.1136/bmj.m2107 10.1136/bmj.m3320 10.1002/ijgo.13329 10.1016/S0140-6736(21)00716-9 10.1038/s41598-020-75096-4 10.1016/j.ajog.2020.03.021 10.1001/jamanetworkopen.2020.30455 10.1038/s41467-020-18933-4 10.1038/s41598-018-38304-w 10.1016/j.jri.2020.103215 10.1002/JLB.3COVA0820-410RRR 10.1016/j.antiviral.2017.03.022 10.1016/j.molcel.2020.08.006 10.1177/2045894020966547 10.15252/emmm.202013001 10.3389/fimmu.2019.00086 10.1038/nm0396-317 10.1159/000052901 10.3389/fimmu.2019.02976 10.1126/sciimmunol.aat6114 10.3389/fimmu.2016.00656 10.1016/0165-0378(91)90024-K 10.3389/fimmu.2020.596489 10.1111/jcmm.15620 10.1038/s41423-020-0473-0 10.3389/fimmu.2017.01138 10.1016/j.immuni.2017.11.001 10.1038/s41467-021-21928-4 10.3389/fimmu.2020.01788 10.1126/sciimmunol.abe1670 10.1016/j.celrep.2019.05.091 10.1016/j.jri.2020.103243 10.1002/eji.202048838 10.1002/cyto.a.24002 10.1038/s41467-020-17292-4 10.4049/jimmunol.1801089 10.1016/j.cyto.2018.08.015 10.1038/ncomms12150 10.1016/j.smim.2016.03.018 10.1038/s41590-017-0022-x 10.1016/j.it.2019.04.012 10.1095/biolreprod.109.081208 10.1002/eji.200636542 10.1371/journal.pone.0085696 10.1002/eji.201948223 10.1002/eji.201970107
Nature Communications; De Biasi S, Tartaro DL et. al.

Jul 31st, 2021 - SARS-CoV-2 infection can affect all human beings, including pregnant women. Thus, understanding the immunological changes induced by the virus during pregnancy is nowadays of pivotal importance. Here, using peripheral blood from 14 pregnant women with asymptomatic or mild SARS-CoV-2 infection, we investigate cell proliferation and cytokine production, measure plasma levels of 62 cytokines, and ...

Single-cell RNA Sequencing of SARS-CoV-2 Cell Entry Factors in the Preconceptional Huma...
https://doi.org/10.1093/humrep/deab183
Human Reproduction (Oxford, England); Vilella F, Wang W et. al.

Jul 31st, 2021 - Are SARS-CoV-2 canonical cell entry machinery, consisting of ACE2, TMPRSS2, NRP1 and LY6E, or alternative potential cell entry machinery, consisting of BSG, ANPEP, CD209, CLEC4G, TMPRSS4, TMPRSS11A, FURIN, CTSB, CTSL and IFITM1, expressed in the human endometrium across the menstrual cycle? Analysis of cell entry factors for SARS-CoV-2 by single-cell RNA-sequencing (scRNAseq) in the preconcepti...

Placental lesions and SARS-Cov-2 infection: Diffuse placenta damage associated to poor ...
https://doi.org/10.1016/j.placenta.2021.07.288
Placenta Bouachba A, Allias F et. al.

Jul 31st, 2021 - Pregnant women with covid-19 are more likely to experience preterm birth. The virus seems to be associated with a wide range of placental lesions, none of them specific. We collected cases of Covid-19 maternal infection during pregnancy associated with poor pregnancy outcomes, for which we received the placenta. We studied clinical data and described pathological findings of placenta and post-m...

How It Started, and How It's Going: Global Family Planning Programs.
https://doi.org/10.1097/GRF.0000000000000625
Clinical Obstetrics and Gynecology; Johnson SA, Kaggwa MN et. al.

Jul 30th, 2021 - Family planning (FP) is the domain that enables people to have their desired number of children if any, and the desired spacing of births. FP initiatives are cross-cutting approaches to empower people with human and reproductive rights, lessen child morbidity and pregnancy-related morbidity and mortality, alleviate poverty, slow climate change, provide sustainable economic growth and developmen...

Developmental and Reproductive Safety of AZD1222 (ChAdOx1 nCoV-19) in Mice.
https://doi.org/10.1016/j.reprotox.2021.07.010
Reproductive Toxicology (Elmsford, N.Y.); Stebbings R, Maguire S et. al.

Jul 30th, 2021 - AZD1222 (ChAdOx1 nCoV-19) is a COVID-19 vaccine that is not yet licensed for use during pregnancy. To support the inclusion of pregnant and breastfeeding people in AZD1222 clinical studies, a non-clinical developmental and reproductive toxicity study was performed to evaluate its effects on fertility and reproductive processes of female CD-1 mice during the embryofetal development phase, and po...

Planning pregnancy during the COVID-19 pandemic: Are the risks worth taking?
https://doi.org/10.1097/01.JAA.0000758264.31916.97
JAAPA : Official Journal of the American Academy of Physi... Vo VD

Jul 29th, 2021 - This literature review assesses recent research highlighting the clinical characteristics of COVID-19 in pregnant patients and children. With better understanding, clinicians can offer risk assessment for those planning pregnancies amid the pandemic while using the best practice guidelines to reassure and assist pregnant patients throughout all spectrums of perinatal care, delivery, and postpar...

Severity of Maternal SARS-CoV-2 Infection in Pregnancy Predicts Neonatal Outcomes.
https://doi.org/10.1055/s-0041-1733783
American Journal of Perinatology; Yasa B, Memur S et. al.

Jul 29th, 2021 - The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) outbreak had an enormous global impact. Pregnant women with SARS-CoV-2 appear to have higher morbidity and mortality. This study aimed to evaluate the effect of the severity of maternal SARS-CoV-2 infection on neonatal outcomes. The clinical and laboratory data of 40 women and neonates evaluated retrospectively. This retrospective...

Maternal COVID-19 disease, vaccination safety in pregnancy, and evidence of protective ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8305214
The Journal of Allergy and Clinical Immunology; Pham A, Aronoff DM et. al.

Jul 28th, 2021 - Maternal COVID-19 disease, vaccination safety in pregnancy, and evidence of protective immunity.|2021|Pham A,Aronoff DM,Thompson JL,|

The impact of COVID-19 pandemic restrictions on pregnancy duration and outcomes in Melb...
https://doi.org/10.1002/uog.23743
Ultrasound in Obstetrics & Gynecology : the Official Jour... Rolnik DL, Matheson A et. al.

Jul 27th, 2021 - To investigate the effect of restriction measures during the COVID-19 pandemic on pregnancy duration and outcomes. We conducted a before and after study with cohort sampling in three maternity hospitals in Melbourne, Australia, including women who were pregnant during the COVID-19 pandemic restriction measures (estimated conception between 1 November 2019 and 29 February 2020) and women who wer...

SARS-CoV-2 and Placental Pathology: Malperfusion Patterns Are Dependent on Timing of In...
https://doi.org/10.1097/PAS.0000000000001772
The American Journal of Surgical Pathology; Glynn SM, Yang YJ et. al.

Jul 27th, 2021 - The extent to which severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection at different points in the pregnancy timeline may affect maternal and fetal outcomes remains unknown. We sought to characterize the impact of SARS-CoV-2 infection proximate and remote from delivery on placental pathology. We performed a secondary analysis of placental pathology from a prospective cohort o...

Women's psychological health, family function, and social support during their third tr...
https://doi.org/10.1017/dmp.2021.244
Disaster Medicine and Public Health Preparedness; He D, Ren J et. al.

Jul 27th, 2021 - The study aims to investigate women's psychological health, family function, and social support during the third trimester within the COVID-19 epidemic. From January 30, 2020 to February 26, 2020, 177 pregnant women during their third trimester (mean gestation time was 37.05±4.06 weeks) in a maternal and children's hospital were investigated using the Self-Rating Anxiety Scale (SAS), the Edinbu...

Associations of COVID-19 related experiences with maternal anxiety and depression: impl...
https://doi.org/10.1016/j.psychres.2021.114115
Psychiatry Research; Lin W, Wu B et. al.

Jul 26th, 2021 - Psychological concerns caused by the COVID-19 pandemic become a public health crisis. It is noteworthy that the associations between COVID-19 related experiences and typical mental symptoms among pregnant women remain unclear. A cross-sectional online survey among pregnant women was conducted in Shenzhen, China. Multivariable logistic regression models were applied to explore the associations o...

Challenges and opportunities during the COVID-19 pandemic: Treating patients for substa...
https://doi.org/10.1016/j.ypmed.2021.106742
Preventive Medicine; Jones HE, Msw EH et. al.

Jul 25th, 2021 - The United States of America faces an opioid use disorder epidemic and growing rates of alcohol and other substance use disorders within the coronavirus disease 2019 (COVID-19) pandemic. Pregnant and post-pregnant individuals are also adversely affected by the epidemic in a pandemic. Physical safety measures preventing COVID-19 also trigger initiation, resumption or intensification of alcohol a...

Death from COVID-19 in a Hispanic postpartum woman and review of the literature.
https://doi.org/10.1136/bcr-2021-242819
BMJ Case Reports; Mydam J, Younes L et. al.

Jul 25th, 2021 - There is still much we do not know about the impact of COVID-19 on the health of pregnant and postpartum women and pregnancy outcomes. Current evidence suggests that there is biological plausibility for worse outcomes among this population. This case report details the clinical care given to a postpartum Hispanic and obese woman diagnosed with COVID-19 in April 2020. We report the care she and ...

SARS-COV-2 infection during pregnancy and risk of preeclampsia: a systematic review and...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8294655
American Journal of Obstetrics and Gynecology; Conde-Agudelo A, Romero R

Jul 25th, 2021 - To examine the relationship between severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection during pregnancy and the risk of preeclampsia. MEDLINE, EMBASE, POPLINE, CINAHL, LILACS, and WHO COVID-19, Chinese, and preprint databases (all from December 1, 2019 to May 31, 2021). Google Scholar, bibliographies, and conference proceedings were also searched. Observational studies that ...

COVID-19 Pandemic-Related Anxiety in Pregnant Women.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8307177
International Journal of Environmental Research and Publi... Nowacka U, Kozlowski S et. al.

Jul 25th, 2021 - The COVID-19 pandemic outbreak influenced general and mental health worldwide. The objective of this study was to assess the anxiety level during the COVID-19 pandemic among pregnant women and compare it between COVID-infected and non-infected groups. We prospectively assessed the daily routine and anxiety level using a bespoke questionnaire and GAD-7 scale validated for pregnant women. With lo...

Pregnancy and birth in the United States during the COVID-19 pandemic: The views of dou...
https://doi.org/10.1111/birt.12580
Birth (Berkeley, Calif.); Adams C

Jul 24th, 2021 - Much of the emerging research on the effects of SARS-CoV-2 disease (COVID-19) on pregnant people and their infants has been clinical, devoting little attention to how the pandemic has affected families navigating pregnancy and birth. This study examined the perspectives of doulas, or nonclinical labor support professionals, on how pregnancy and birth experiences and maternal health care deliver...

Hofbauer cells and coronavirus disease 2019 (COVID-19) in pregnancy: Molecular patholog...
https://doi.org/10.5858/arpa.2021-0296-SA
Archives of Pathology & Laboratory Medicine; Schwartz DA, Baldewijns M et. al.

Jul 24th, 2021 - - Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can undergo maternal-fetal transmission, heightening interest in the placental pathology findings from this infection. Transplacental SARS-CoV-2 transmission is typically accompanied by chronic histiocytic intervillositis together with necrosis and positivity of syncytiotrophoblast for SARSCoV-2. Hofbauer cells are placental macroph...