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SARS-CoV-2 Infection and COVID-19 During Pregnancy: A Multidisciplinary Review.
https://doi.org/10.1016/j.mayocp.2020.05.011
Mayo Clinic Proceedings; Narang K, Enninga EAL et. al.

Aug 5th, 2020 - The global pandemic of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the cause of coronavirus disease 2019 (COVID-19), has been associated with worse outcomes in several patient populations, including the elderly and those with chronic comorbidities. Data from previous pandemics and seasonal influenza suggest that pregnant women may be at increased risk for infection-associated ...

Approaches to screening for hyperglycaemia in pregnant women during and after the COVID...
https://doi.org/10.1111/dme.14380
Diabetic Medicine : a Journal of the British Diabetic Association; Meek CL, Lindsay RS et. al.

Aug 4th, 2020 - To evaluate the diagnostic and prognostic performance of alternative diagnostic strategies to oral glucose tolerance tests, including random plasma glucose, fasting plasma glucose and HbA1c , during the COVID-19 pandemic. Retrospective service data (Cambridge, UK; 17 736 consecutive singleton pregnancies, 2004-2008; 826 consecutive gestational diabetes pregnancies, 2014-2019) and 361 women with...

Is Pregnancy an Immunological Contributor to Severe or Controlled COVID-19 Disease?
https://doi.org/10.1111/aji.13317
American Journal of Reproductive Immunology (New York, N.Y. : 1989); Hanna N, Hanna M et. al.

Aug 4th, 2020 - Since its emergence in Wuhan as a novel coronavirus disease, it has taken only a few months since January 2020 for it to be recognized as a wide spread COVID-19 pandemic which has contributed to global health devastation. As pointed out by health experts, it is a once in a century pandemic of our times. Clinical observations so far indicate that the older population and immune compromised indiv...

Preparedness, administrative challenges for establishing obstetric services, and experi...
https://doi.org/10.1002/ijgo.13338
International Journal of Gynaecology and Obstetrics: the Official Organ of the International Federation of Gynaecology and Obstetrics; Mahajan NN, Pednekar R et. al.

Aug 4th, 2020 - To provide a descriptive account of the challenges and administrative preparedness for establishing and sustaining safe obstetric services during the COVID-19 pandemic at Topiwala National Medical College & BYL Nair Charitable Hospital (NH), Mumbai, India. The management of pregnant women with COVID-19 was implemented as per international (WHO, RCOG, ACOG) and national (Indian Council of Medica...

Vertical Transmission of SARS-CoV-2 (COVID-19): Are Hypotheses More than Evidences?
https://doi.org/10.1055/s-0040-1714346
American Journal of Perinatology; Auriti C, De Rose DU et. al.

Aug 4th, 2020 - In spite of the increasing, accumulating knowledge on the novel pandemic coronavirus severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), questions on the coronavirus disease-2019 (COVID-19) infection transmission from mothers to fetuses or neonates during pregnancy and peripartum period remain pending and have not been addressed so far. SARS-CoV-2, a RNA single-stranded virus, has bee...

Placental SARS-CoV-2 in a Pregnant Woman with Mild COVID-19 Disease.
https://doi.org/10.1002/jmv.26386
Journal of Medical Virology; Hsu AL, Guan M et. al.

Aug 3rd, 2020 - The full impact of COVID-19 on pregnancy remains uncharacterized. Current literature suggests minimal maternal, fetal, and neonatal morbidity and mortality.1 COVID-19 manifestations appear similar between pregnant and non-pregnant women.2 OBJECTIVES/STUDY DESIGN: We present a case of placental SARS-CoV-2 virus in a woman with mild COVID-19 disease, then review the literature. RT-PCR was perform...

SARS-CoV-2 can infect the placenta and is not associated with specific placental histop...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7395938
Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc; Hecht JL, Quade B et. al.

Aug 3rd, 2020 - Congenital infection of SARS-CoV-2 appears to be exceptionally rare despite many cases of COVID-19 during pregnancy. Robust proof of placental infection requires demonstration of viral localization within placental tissue. Only two of the few cases of possible vertical transmission have demonstrated placental infection. None have shown placental expression of the ACE2 or TMPRSS2 protein, both r...

Possible Coronavirus Disease 2019 Pandemic and Pregnancy: Vertical Transmission Is Not ...
https://doi.org/10.1097/INF.0000000000002816
The Pediatric Infectious Disease Journal; Marzollo R, Aversa S et. al.

Aug 2nd, 2020 - Coronavirus disease 2019 outbreak has a growing impact on global health; vertical transmission of severe acute respiratory syndrome coronavirus 2 infection is still controversial. In this article, we describe a case of vertical transmission of severe acute respiratory syndrome coronavirus 2 in a newborn with respiratory and gastrointestinal symptoms.

Cryopreservation in reproductive medicine during the COVID-19 pandemic: rethinking poli...
https://doi.org/10.1093/humrep/deaa210
Human Reproduction (Oxford, England); Alteri A, Pisaturo V et. al.

Aug 2nd, 2020 - Cryopreservation of reproductive cells and tissues represents an essential aspect of ART practices that might be particularly strategic and helpful during SARS-CoV-2 emergency. However, recommendations on how and when to preserve reproductive tissues and cells during a novel severe pandemic are scanty. This paper uses a SWOT (strengths, weaknesses, opportunities and threats) analysis to identif...

Testing for gestational diabetes during the COVID-19 pandemic. An evaluation of propose...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7391984
Diabetes Research and Clinical Practice; David McIntyre H, Gibbons KS et. al.

Aug 2nd, 2020 - We assessed how altered diagnostic processes and criteria for gestational diabetes mellitus (GDM) recommended by the United Kingdom (UK), Canada and Australia for use during the COVID-19 pandemic would affect both GDM frequency and related adverse outcomes. Secondary analysis of 5974 HAPO study women with singleton pregnancies who underwent 75g OGTTs and HbA1c assays between 24 and 32 weeks' ge...

Vertical Transmission of COVID-19: A Systematic Review and Meta-analysis.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7392880
American Journal of Obstetrics and Gynecology; Kotlyar A, Grechukhina O et. al.

Aug 2nd, 2020 - We sought to conduct a systematic review of the current literature to determine estimates of vertical transmission of COVID-19 based upon early RNA detection of SARS-CoV-2 after birth from various neonatal/fetal sources and neonatal serology. Eligible studies published up to May 28, 2020 were retrieved from Pubmed, EMbase, MedRXiv, BioRXiv collection databases. This systematic review included c...

Sars-CoV-2 in pregnancy: Why is it better than expected?
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7378463
European Journal of Obstetrics, Gynecology, and Reproductive Biology; Ghi T, di Pasquo E et. al.

Aug 2nd, 2020 - Since the outbreak of Coronavirus disease in December 2019, information specific to pregnancy remains limited and controversial. Based on data from previous reports, it has been noticed that contrary to prior pandemics such as SARS, MERS and H1N1 and although pregnancy is usually considered as a condition of high susceptibility to viral infections, new SARS-CoV2 infection seems to have a more b...

What immunological and hormonal protective factors lower the risk of COVID-19 related d...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7368414
Journal of Reproductive Immunology; Berhan Y

Aug 2nd, 2020 - Despite anticipated increased risk of COVID-19 and increased expression of the SARS CoV-2 receptor (ACE2), the relatively low mortality of pregnant women with COVID-19 has been an area of wonder. The immunological changes predominantly inclining to anti-inflammatory state, which is augmented by placental hormones' immune modulating action, looks against with COVID-19 inflammatory reaction leadi...

Maternal COVID-19 infection, clinical characteristics, pregnancy, and neonatal outcome:...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7362841
European Journal of Obstetrics, Gynecology, and Reproductive Biology; Antoun L, Taweel NE et. al.

Jul 31st, 2020 - To study the effect of COVID-19 on pregnancy and neonatal outcomes. Prospective cohort study in a large tertiary maternity unit within a university hospital with an average annual birth of over 10,000 births. We prospectively collected and analysed data for a cohort of 23 pregnant patients including singleton and multiple pregnancies tested positive for COVID-19 between February 2020 and April ...

Racial and ethnic disparities in severity of COVID-19 disease in pregnancy in the Unite...
https://doi.org/10.1002/ijgo.13333
International Journal of Gynaecology and Obstetrics: the Official Organ of the International Federation of Gynaecology and Obstetrics; Onwuzurike C, Diouf K et. al.

Jul 31st, 2020 - Throughout the COVID-19 pandemic, limited racial and ethnic data have been published about the prevalence and severity of the disease in pregnant women. Ethical approval was obtained from the Brigham and Women's Hospital Institutional Review Board. The present study reviewed the cases of women at an academic hospital-based obstetrics practice diagnosed with COVID-19 during pregnancy or within e...

Coronavirus (COVID-19) Update: FDA Posts New Template for At-Home and Over-the-Counter Diagnostic Tests for Use in Non-Lab Settings, Such as Homes, Offices or Schools | FDA
https://www.fda.gov/news-events/press-announcements/coronavirus-covid-19-update-fda-posts-new-template-home-and-over-counter-diagnostic-tests-use-non

Jul 30th, 2020 - For Immediate Release: July 29, 2020 Español Today, the U.S. Food and Drug Administration posted a new template for commercial developers to help them develop and submit emergency use authorization (EUA) requests for COVID-19 diagnostic tests that can be performed entirely at home or in other settings besides a lab, such as offices or schools, and that could be available without a prescription....

COVID-19 (SARS-CoV-2) Infection in Pregnancy: A Systematic Review.
https://doi.org/10.1159/000509290
Gynecologic and Obstetric Investigation; Akhtar H, Patel C et. al.

Jul 29th, 2020 - To review published studies related to the association of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections with pregnancy, foetal, and neonatal outcomes during coronavirus disease 2019 (COVID-19) pandemic in a systematic manner. A comprehensive electronic search was done through PubMed, Scopus, Medline, Cochrane database, and Google Scholar from December 01, 2019, to May ...

Neonatal outcome in 29 pregnant women with COVID-19: A retrospective study in Wuhan, Ch...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7386573
PLoS Medicine; Wu YT, Liu J et. al.

Jul 29th, 2020 - As of June 1, 2020, coronavirus disease 2019 (COVID-19) has caused more than 6,000,000 infected persons and 360,000 deaths globally. Previous studies revealed pregnant women with COVID-19 had similar clinical manifestations to nonpregnant women. However, little is known about the outcome of neonates born to infected women. In this retrospective study, we studied 29 pregnant women with COVID-19 ...

COVID-19 and Hypercoagulability: Potential Impact on Management with Oral Contraceptive...
https://doi.org/10.1210/endocr/bqaa121
Endocrinology Spratt DI, Buchsbaum RJ

Jul 28th, 2020 - COVID-19 and Hypercoagulability: Potential Impact on Management with Oral Contraceptives, Estrogen Therapy and Pregnancy.|2020|Spratt DI,Buchsbaum RJ,|

Early Childhood Health Outcomes Following In Utero Exposure to Influenza Vaccines: A Sy...
https://doi.org/10.1542/peds.2020-0375
Pediatrics Foo DYP, Sarna M et. al.

Jul 28th, 2020 - Vaccination during pregnancy is an effective strategy for preventing infant disease; however, little is known about early childhood health after maternal vaccination. To systematically review the literature on early childhood health associated with exposure to influenza vaccines in utero. We searched CINAHL Plus, Embase, Medline, Scopus, and Web of Science for relevant articles published from i...