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Polysaccharides to combat viruses (Covid-19) and microbes: New updates.
https://doi.org/10.2174/1874467215666220112150332
Current Molecular Pharmacology; AlMatar M, Makky EA et. al.

Jan 14th, 2022 - COVID-19, which is speedily distributed across the world and presents a significant challenge to public health, is caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Following MERS coronavirus (MERS-CoV) and SARS, this is the third severe coronavirus outbreak in less than 20 years. To date, there are no exact agents and vaccines available for the treatment of COVID-19 t...

SARS-CoV-2 Environmental contamination in hospital rooms is uncommon using viral cultur...
https://doi.org/10.1093/cid/ciac023
Clinical Infectious Diseases : an Official Publication Of... Warren BG, Nelson A et. al.

Jan 14th, 2022 - We assessed environmental contamination of inpatient rooms housing COVID-19 patients in a dedicated COVID-19 unit. Contamination with SARS-CoV-2 was found on 5.5% (19/347) of surfaces via RT-PCR and 0.3% (1/347) of surfaces via cell culture. Environmental contamination is uncommon in hospitals rooms; RNA presence is not a specific indicator of infectious virus.

UltraViolet SANitizing System for Sterilization of Ambulances Fleets and for Real-Time ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8750941
International Journal of Environmental Research and Publi... Michelini Z, Mazzei C et. al.

Jan 12th, 2022 - The contamination of ambulances with pathogenic agents represents a potential threat for the public health, not only for common pathogens but also for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The aim of this project was to exploits the germicidal effect of the UVC radiation at 254 nm to sanitize the patient's compartment of ambulances with an advanced UltraViolet SANitizing...

Evidence of Air and Surface Contamination with SARS-CoV-2 in a Major Hospital in Portugal.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8744945
International Journal of Environmental Research and Publi... Silva PGD, Gonçalves J et. al.

Jan 12th, 2022 - As the third wave of the COVID-19 pandemic hit Portugal, it forced the country to reintroduce lockdown measures due to hospitals reaching their full capacities. Under these circumstances, environmental contamination by SARS-CoV-2 in different areas of one of Portugal's major Hospitals was assessed between 21 January and 11 February 2021. Air samples (n = 44) were collected from eleven different...

Cleaning and disinfecting surfaces in hospitals and long-term care facilities for reduc...
https://doi.org/10.1016/j.jhin.2021.12.017
The Journal of Hospital Infection; Thomas RE, Thomas BC et. al.

Jan 10th, 2022 - Multiply drug-resistant organisms (MDROs) in hospitals and long-term care facilities (LTCFs) of particular concern include meticillin-resistant Staphylococcus aureus (MRSA), vancomycin-resistant enterococcus, multidrug-resistant Acinetobacter species and extended spectrum beta-lactamase producing organisms. Respiratory viruses include influenza and SARS-CoV-2. To assess effectiveness of cleanin...

Quantifying environmental mitigation of aerosol viral load in a controlled chamber with...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8755398
Clinical Infectious Diseases : an Official Publication Of... Parhizkar H, Dietz L et. al.

Jan 8th, 2022 - Several studies indicate that COVID-19 is primarily transmitted within indoor spaces. Therefore, environmental characterization of SARS-CoV-2 viral load with respect to human activity, building parameters, and environmental mitigation strategies is critical to combat disease transmission. We recruited 11 participants diagnosed with COVID-19 to individually occupy a controlled chamber and conduc...

Pandemic Patterns: How Artistic Depictions of Past Epidemics Illuminate Thematic and St...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8722652
Journal of General Internal Medicine; Hanson M, Small L

Jan 5th, 2022 - From the beginning of recorded history, human beings have encountered epidemics. They have also memorialized these events, which can be deeply traumatic and scarring, in visual art and literature. In this article, we look at a selection of artistic depictions of past epidemics in Western culture in light of what they can teach us about COVID-19 today. Our analysis reveals that while responses t...

Etesevimab - etesevimab injection, solution-Eli Lilly and Company
https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=aacdd8a7-18b7-43c6-b866-14aa491a0c15

Jan 4th, 2022 - SPL UNCLASSIFIED SECTION TREATMENT The U.S. Food and Drug Administration (FDA) has issued an Emergency Use Authorization (EUA) to permit the emergency use of the unapproved products bamlanivimab and etesevimab administered together for the treatment of mild to moderate coronavirus disease 2019 (COVID-19) in adults and pediatric patients, including neonates, with positive results of direct SARS-...

Active environmental surveillance of SARS-CoV-2 in Midwestern United States meatpacking...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8719691
PloS One; Storms SM, Lowe JF

Jan 1st, 2022 - This pilot project investigated environmental SARS-CoV-2 presence in seven Midwestern meatpacking plants from May 2020 to January 2021. This study investigated social distancing and infection control practices and incorporated environmental sampling of surfaces and air in employee common areas. All plants increased their social distancing efforts, increased the frequency of cleaning and disinfe...

Spatial and temporal effects on severe acute respiratory coronavirus virus 2 (SARS-CoV-...
https://doi.org/10.1017/ice.2021.530
Infection Control and Hospital Epidemiology; Ziegler MJ, Huang E et. al.

Dec 28th, 2021 - The spatial and temporal extent of severe acute respiratory coronavirus virus 2 (SARS-CoV-2) environmental contamination has not been precisely defined. We sought to elucidate contamination of different surface types and how contamination changes over time. We sampled surfaces longitudinally within COVID-19 patient rooms, performed quantitative RT-PCR for the detection of SARS-CoV-2 RNA, and mo...

Oh, Deer: Coronavirus Running Buck Wild in Ohio
https://www.medpagetoday.com/infectiousdisease/covid19/96369

Dec 23rd, 2021 - About one-third of white-tail deer tested in northeastern Ohio earlier this year were carrying the coronavirus responsible for COVID-19, according to a newly published study. Out of 360 animals killed and collected by researchers from January to March, 129 were positive for SARS-CoV-2 in PCR testing, reported Andrew Bowman, MS, DVM, PhD, of Ohio State University's College of Veterinary Medicine...

Sotrovimab - sotrovimab injection, solution, concentrate-GlaxoSmithKline LLC
https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=aa5cca2e-4351-4f81-b0e5-3303ac0b2474

Dec 22nd, 2021 - SPL UNCLASSIFIED SECTION The U.S. Food and Drug Administration (FDA) has issued an Emergency Use Authorization (EUA) to permit the emergency use of the unapproved product sotrovimab for the treatment of mild-to-moderate coronavirus disease 2019 (COVID-19) in adults and pediatric patients (12 years of age and older weighing at least 40 kg) with positive results of direct SARS-CoV-2 viral testing...

Bamlanivimab - bamlanivimab injection, solution-Eli Lilly and Company
https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=c7e9d8a6-e8c2-4681-9362-51d5bdbae00d

Dec 22nd, 2021 - SPL UNCLASSIFIED SECTION TREATMENT The U.S. Food and Drug Administration (FDA) has issued an Emergency Use Authorization (EUA) to permit the emergency use of the unapproved products bamlanivimab and etesevimab administered together for the treatment of mild to moderate coronavirus disease 2019 (COVID-19) in adults and pediatric patients, including neonates, with positive results of direct SARS-...

Rapid SARS-CoV-2 Inactivation in a Simulated Hospital Room Using a Mobile and Autonomou...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8690105
The Journal of Infectious Diseases; Lorca-Oró C, Vila J et. al.

Dec 15th, 2021 - The spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) since 2019 has made mask-wearing, physical distancing, hygiene, and disinfection complementary measures to control virus transmission. Especially for health facilities, we evaluated the efficacy of an UV-C autonomous robot to inactivate SARS-CoV-2 desiccated on potentially contaminated surfaces. ASSUM (autonomous sanitar...

Pediatric Haemophilus Influenzae Infection
https://emedicine.medscape.com/article/964317-overview

Dec 14th, 2021 - Background Although the type of infectious diseases caused by Haemophilus influenzae has changed considerably in recent years because of the widespread and routine immunization of children against type b organisms, H influenzae remains a significant pathogen. The recent vaccine shortage in the United States from December 2007 to September 2009 is a reminder that despite the decline in the incid...

Pediatric Haemophilus Influenzae Infection
http://emedicine.medscape.com/article/964317-overview

Dec 14th, 2021 - Background Although the type of infectious diseases caused by Haemophilus influenzae has changed considerably in recent years because of the widespread and routine immunization of children against type b organisms, H influenzae remains a significant pathogen. The recent vaccine shortage in the United States from December 2007 to September 2009 is a reminder that despite the decline in the incid...

Pediatric Haemophilus Influenzae Infection
https://emedicine.medscape.com/article/964317-print

Dec 14th, 2021 - Background Although the type of infectious diseases caused by Haemophilus influenzae has changed considerably in recent years because of the widespread and routine immunization of children against type b organisms, H influenzae remains a significant pathogen. The recent vaccine shortage in the United States from December 2007 to September 2009 is a reminder that despite the decline in the incid...

Association between COVID-19 infection rates by region and implementation of non-pharma...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8689709
Journal of Public Health (Oxford, England); Anan T, Ishimaru T et. al.

Dec 8th, 2021 - During a pandemic, non-pharmaceutical interventions (NPIs) play an important role in protecting oneself and others from infection. There are large regional differences in COVID-19 infection rates in Japan. We hypothesized that the local infection incidence may affect adherence to individual NPIs. This cross-sectional study was conducted online among full-time workers in Japan in December 2020. ...

Surface and air contamination with SARS-CoV-2 from hospitalized COVID-19 patients in To...
https://doi.org/10.1093/infdis/jiab578
The Journal of Infectious Diseases; Kotwa JD, Jamal AJ et. al.

Dec 2nd, 2021 - We determined the burden of SARS-CoV-2 in air and on surfaces in rooms of patients hospitalized with COVID-19 and investigated patient characteristics associated with SARS-CoV-2 environmental contamination. Nasopharyngeal swabs, surface, and air samples were collected from the rooms of 78 inpatients with COVID-19 at six acute care hospitals in Toronto from March to May 2020. Samples were tested...

Aerosol tracer testing in Boeing 767 and 777 aircraft to simulate exposure potential of...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8635387
PloS One; Kinahan SM, Silcott DB et. al.

Dec 2nd, 2021 - The COVID-19 pandemic has reintroduced questions regarding the potential risk of SARS-CoV-2 exposure amongst passengers on an aircraft. Quantifying risk with computational fluid dynamics models or contact tracing methods alone is challenging, as experimental results for inflight biological aerosols is lacking. Using fluorescent aerosol tracers and real time optical sensors, coupled with DNA-tag...