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Modular capsid decoration boosts adenovirus vaccine-induced humoral immunity against SA...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9364715
Molecular Therapy : the Journal of the American Society O... Dicks MDJ, Rose LM et. al.

Aug 12th, 2022 - Adenovirus vector vaccines have been widely and successfully deployed in response to COVID-19. However, despite inducing potent T cell immunity, improvement of vaccine-specific antibody responses upon homologous boosting is modest compared to other technologies. Here, we describe a system enabling modular decoration of adenovirus capsid surfaces with antigens and demonstrate potent induction of...

Influenza Clinical Presentation
http://emedicine.medscape.com/article/219557-clinical

Aug 10th, 2022 - History The presentation of influenza virus infection varies; however, it usually includes many of the symptoms described below. Patients with influenza who have preexisting immunity or who have received vaccine may have milder symptoms. Onset of illness can occur suddenly over the course of a day, or it can progress more slowly over the course of several days. Typical signs and symptoms includ...

Influenza Clinical Presentation
https://emedicine.medscape.com/article/219557-clinical

Aug 10th, 2022 - History The presentation of influenza virus infection varies; however, it usually includes many of the symptoms described below. Patients with influenza who have preexisting immunity or who have received vaccine may have milder symptoms. Onset of illness can occur suddenly over the course of a day, or it can progress more slowly over the course of several days. Typical signs and symptoms includ...

Environmental detection of SARS-CoV-2 in hospital rooms in different wards of an Univer...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9356633
The Journal of Hospital Infection; Barrigah-Benissan K, Ory J et. al.

Aug 10th, 2022 - Transmission of SARS-CoV-2 can occur through direct, indirect, or close contact with infected people. However, the extent of environmental contamination is unknown. The nature of the relation between patients' symptoms and SARS-CoV-2 environmental shedding remains unclear. The aim of this study was to assess the relationship between patient covid-19 status and environmental contamination. Betwe...

COVID vs Monkeypox: A Tale of Two Pandemics
https://www.medscape.com/viewarticle/978655

Aug 10th, 2022 - Welcome to Impact Factor, your weekly dose of commentary on a new medical study. I'm Dr F. Perry Wilson of the Yale School of Medicine. Toward the end of 2019, we all took a crash course in virology and infectious disease epidemiology as we struggled with what was, for many of us, the first major pandemic of our lifetimes. We've learned a lot since then — we've upped our game when it comes to t...

Bebtelovimab - bebtelovimab injection, solution-Eli Lilly and Company
https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=fd8dc07c-3aae-4cc2-a547-3a19357411ca

Aug 5th, 2022 - SPL UNCLASSIFIED SECTION HIGHLIGHTS OF EMERGENCY USE AUTHORIZATION (EUA) These highlights of the EUA do not include all the information needed to use BEBTELOVIMAB under the EUA. See the FULL FACT SHEET FOR HEALTHCARE PROVIDERS for BEBTELOVIMAB. BEBTELOVIMAB injection for intravenous use Original EUA Authorized Date: 02/2022 Revised EUA Authorized Date: 08/2022 ----------------------------RECENT...

Nanocomposite coatings for the prevention of surface contamination by coronavirus.
https://doi.org/10.1371/journal.pone.0272307
PloS One; Toledo E, Dim S et. al.

Aug 3rd, 2022 - The current Covid-19 pandemic has a profound impact on all aspects of our lives. Aside from contagion by aerosols, the presence of the SARS-CoV-2 is ubiquitous on surfaces that millions of people handle daily. Therefore, controlling this pandemic involves the reduction of potential infections via contaminated surfaces. We developed antiviral surfaces by preparing suspensions of copper and cupri...

Methylene blue applied to N95 respirators and medical masks for SARS-CoV-2 decontaminat...
https://doi.org/10.1016/j.ajic.2022.03.003
American Journal of Infection Control; Lendvay TS, Xu J et. al.

Aug 1st, 2022 - Global shortage of personal protective equipment (PPE), as consequence of the COVID-19 global pandemic, has unmasked significant resource inequities prompting efforts to develop methods for safe PPE decontamination for reuse. The World Health Organization (WHO) in their Rational Use of PPE bulletin cited the use of a photodynamic dye, methylene blue, and light exposure as a viable option for N9...

Of masks and methylene blue-The use of methylene blue photochemical treatment to decont...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9329083
American Journal of Infection Control; Wielick C, Fries A et. al.

Aug 1st, 2022 - In the context of the SARS-CoV-2 pandemic, reuse of personal protective equipment, specifically that of medical face coverings, has been recommended. The reuse of these typically single-use only items necessitates procedures to inactivate contaminating human respiratory and gastrointestinal pathogens. We previously demonstrated decontamination of surgical masks and respirators contaminated with...

Ozone Eliminates SARS-CoV-2 from Difficult-to-Clean Office Supplies and Clinical Equipm...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9321385
International Journal of Environmental Research and Publi... Torres-Mata LB, García-Pérez O et. al.

Jul 28th, 2022 - (1) Background: Severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2) continues to cause profound health, economic, and social problems worldwide. The management and disinfection of materials used daily in health centers and common working environments have prompted concerns about the control of coronavirus disease 2019 (COVID-19) infection risk. Ozone is a powerful oxidizing agent ...

Assessment of Surface Disinfection Effectiveness of Decontamination System COUNTERFOG® ...
https://doi.org/10.1007/s12560-022-09526-z
Food and Environmental Virology; Del Álamo C, Vázquez-Calvo Á et. al.

Jul 20th, 2022 - The experience of COVID19 pandemic has demonstrated the real concern of biological agents dispersed in the air and surfaces environments. Therefore, the need of a fast and large-scale disinfection method has arisen for prevention of contagion. COUNTERFOG® is an innovative technology developed for large-scale decontamination of air and surfaces. The objective of this study is to assess experimen...

Complement C3 activation in the ICU: Disease and therapy as Bonnie and Clyde.
https://doi.org/10.1016/j.smim.2022.101640
Seminars in Immunology; Mannes M, Mastellos DC et. al.

Jul 20th, 2022 - Patients in the intensive care unit (ICU) often straddle the divide between life and death. Understanding the complex underlying pathomechanisms relevant to such situations may help intensivists select broadly acting treatment options that can improve the outcome for these patients. As one of the most important defense mechanisms of the innate immune system, the complement system plays a crucia...

China Tells Local Governments to Drop COVID Tests on Some Goods
https://www.medscape.com/viewarticle/976981

Jul 13th, 2022 - BEIJING (Reuters) - China's health authority said on Tuesday that local governments no longer need to test some imported goods for the coronavirus, in a move aimed at reducing the cost of its strict COVID-19 prevention measures. China began testing the packaging of chilled and frozen food imports for the virus in June 2020, after a cluster of infections among workers at a wholesale food market ...

Inanimate Surfaces as a Source of Hospital Infections Caused by Fungi, Bacteria and Vir...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9265696
International Journal of Environmental Research and Publi... Jabłońska-Trypuć A, Makuła M et. al.

Jul 10th, 2022 - The carriers of nosocomial infections are the hands of medical personnel and inanimate surfaces. Both hands and surfaces may be contaminated as a result of contact with the patient, their body fluids, and touching contaminated surfaces in the patient's surroundings. Visually clean inanimate surfaces are an important source of pathogens. Microorganisms have properties thanks to which they can su...

Workers' Perception Heat Stress: Results from a Pilot Study Conducted in Italy during t...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9266050
International Journal of Environmental Research and Publi... Bonafede M, Levi M et. al.

Jul 10th, 2022 - Many workers are exposed to the effects of heat and often to extreme temperatures. Heat stress has been further aggravated during the COVID-19 pandemic by the use of personal protective equipment to prevent SARS-CoV-2 infection. However, workers' risk perception of heat stress is often low, with negative effects on their health and productivity. The study aims to identify workers' needs and gap...

Individual Differences in Germ Spreading Behaviors Among Children With Attention-Defici...
https://doi.org/10.1093/jpepsy/jsac056
Journal of Pediatric Psychology; Hernandez ML, Spiegel JA et. al.

Jul 2nd, 2022 - Infectious diseases, such as coronavirus disease 2019 (COVID-19), are commonly transmitted by respiratory droplets and contact with contaminated surfaces. Individuals with attention-deficit/hyperactivity disorder (ADHD) are more likely to be infected with COVID-19 and experience more hospitalizations than individuals without ADHD. The current study investigated the role of ADHD symptomatology a...

Transmission of SARS-CoV-2 on Cold-Chain Food: Precautions Can Effectively Reduce the R...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9244345
Food and Environmental Virology; Guo M, Yan J et. al.

Jun 30th, 2022 - The COVID-19 pandemic has generated a new era in the world, also in the food safety. Up to now, there is no evidence to suggest that people can infect COVID-19 via food contaminated by SARS-CoV-2. Here, we analyzed the results of regular SARS-CoV-2 nucleic acid testing of considerable cold-chain food practitioners, cold-chain food surfaces, and their internal or external packaging as well as th...

Disinfection and decontamination in the context of SARS-CoV-2-specific data.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9350315
Journal of Medical Virology; Cimolai N

Jun 28th, 2022 - Given the high transmissibility of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) as witnessed early in the coronavirus disease 2019 (COVID-19) pandemic, concerns arose with the existing methods for virus disinfection and decontamination. The need for SARS-CoV-2-specific data stimulated considerable research in this regard. Overall, SARS-CoV-2 is practically and equally susceptibl...

Does Temporal Stability Moderate Reasoned Action Approach Relations With Covid-19 Preve...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9278224
Annals of Behavioral Medicine : a Publication of the Soci... Norman P, Wilding S et. al.

Jun 28th, 2022 - Preventive behaviors continue to play an important role in reducing the spread of the SARS-CoV-2 virus. This study aimed to apply the reasoned action approach (RAA) to predict Covid-19 preventive intentions and behavior and to test whether temporal stability moderates relations between RAA constructs and behavior. A representative sample of UK adults (N = 603) completed measures of RAA variable...

Novel case of Candida auris in the Veterans Health Administration and in the state of S...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9221678
American Journal of Infection Control; Lucy A, Paula G et. al.

Jun 26th, 2022 - The emerging pathogen Candida auris poses major infection prevention challenges as the organism can remain on surfaces for unknown timeframes and can cause severe illness. These challenges are exacerbated in the health care environment with potential spread to a vulnerable population. This report describes the Columbia Veterans Administration Health Care System's encounter with this significant...