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Coronavirus (COVID-19) Update: Daily Roundup August 6, 2020 | FDA
https://www.fda.gov/news-events/press-announcements/coronavirus-covid-19-update-daily-roundup-august-6-2020

Aug 6th, 2020 - For Immediate Release: August 06, 2020 The U.S. Food and Drug Administration today announced the following actions taken in its ongoing response effort to the COVID-19 pandemic: On August 4, the FDA issued Emergency Use Authorizations (EUAs) for ventilator-related devices to: Lombardi Undersea, for its Subsalve Oxygen Treatment Hood, which is a patient interface intended for helmet-based Non-In...

Traditional Chinese medicine for the treatment of pulmonary fibrosis: A protocol for sy...
https://doi.org/10.1097/MD.0000000000021310
Medicine Li LJ, Chen X et. al.

Aug 5th, 2020 - Since December 2019, there have been many cases of viral pneumonia of unknown causes in Wuhan City, Hubei Province. During the period of novel coronavirus, according to the observation of limited autopsy and biopsy pathological results, pulmonary interstitial fibrosis appeared in some pathological changes of lung. Idiopathic pulmonary fibrosis (IPF) is a chronic progressive interstitial pneumon...

Peripheral Blood Examination Findings in SARS-CoV-2 Infection.
https://doi.org/10.1093/ajcp/aqaa108
American Journal of Clinical Pathology; Nazarullah A, Liang C et. al.

Aug 5th, 2020 - Peripheral blood abnormalities in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have not been fully elucidated. We report qualitative and quantitative peripheral blood findings in coronavirus disease 2019 (COVID-19) patients and compare them with a control group. We reviewed electronic medical records, complete blood counts, peripheral blood smears, and flow cytometry data in 12 ...

Prevalence and Mortality of COVID-19 Patients With Gastrointestinal Symptoms: A Systema...
https://doi.org/10.1016/j.mayocp.2020.06.003
Mayo Clinic Proceedings; Tariq R, Saha S et. al.

Aug 5th, 2020 - To perform a systematic review and meta-analysis evaluating the prevalence of gastrointestinal (GI) symptoms and mortality in patients with coronavirus disease 2019 (COVID-19) diagnosed. A systematic search of MEDLINE, EMBASE, Cochrane Central Register of Controlled Trials, Cochrane Database of Systematic Reviews, and Scopus was performed from December 1, 2019 to May 7, 2020. Observational stud...

Covid-19 Infection in Older Adults: A Geriatrician's Perspective.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7351627
Clinical Interventions in Aging; Isik AT

Aug 5th, 2020 - The pandemic of the Covid-19 virus has become the main issue all over the world. In its current form, the disease is more severe in geriatric cases and individuals with chronic disease, even causing death. In older adults and atypical presentations, testing strategies for Covid-19, potential drug interactions of experimental Covid-19 therapies, and ageism are important issues in the course of t...

Corticosteroid, oseltamivir, and delayed admission are independent risk factors for pro...
https://doi.org/10.1111/crj.13243
The Clinical Respiratory Journal; Hu F, Yin G et. al.

Aug 4th, 2020 - Coronavirus Disease 2019 (COVID-19) has spread worldwide, and it has reached to more than 14.5 million cases. Although Hubei province is the epicenter of China, little is known about epidemiological and clinical features of COVID-19 in other areas in Hubei province around Wuhan. In addition, the virological data, particularly the factors associated with viral shedding of COVID-19 has not been w...

Covid-19-Beyond virology: Potentials for maintaining mental health during lockdown.
https://doi.org/10.1371/journal.pone.0236688
PloS One; Munk AJL, Schmidt NM et. al.

Aug 4th, 2020 - The current study aimed to assess prevalence of mental disorders during Covid-19 pandemic- and respective lockdown in Germany, and potential behaviors/states that can have protective functions on preventing severe mental problems. Assessing prevalence of mental disorders, as well as to find potential protective variables is very important in order to determine people's psychological suffering. ...

Guillain Barré Syndrome associated with SARS-CoV-2 infection. A Systematic Review.
https://doi.org/10.1111/ene.14462
European Journal of Neurology; De Sanctis P, Doneddu PE et. al.

Aug 4th, 2020 - Guillain-Barré syndrome (GBS) incidence can increase during outbreaks of infectious illnesses. A few cases of GBS associated with coronavirus disease 2019 (COVID-19) infection have been reported. To identify specific clinical features of GBS associated with COVID-19. We searched Pubmed, EMBASE and Cochrane from November 1, 2019 to May 17, 2020 and included all papers with full text in English, ...

High Prevalence of Headaches During Covid-19 Infection: A Retrospective Cohort Study.
https://doi.org/10.1111/head.13923
Headache References; Poncet-Megemont L, Paris P et. al.

Aug 4th, 2020 - To document the prevalence of new headaches in patients with Covid-19 infection and the potential association with other neuro-sensorial symptoms (anosmia and ageusia). The persistence of these symptoms 1 month after recovery was also documented. Headaches are a very common symptom of viral infections. Surprisingly, early Chinese studies reported a relatively low prevalence (12-15%) of headache...

A consideration of publication-derived immune-related associations in Coronavirus and r...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7397454
Journal of Translational Medicine; Geifman N, Whetton AD

Aug 4th, 2020 - The severe acute respiratory syndrome virus SARS-CoV-2, a close relative of the SARS-CoV virus, is the cause of the recent COVID-19 pandemic affecting, to date, over 14 million individuals across the globe and demonstrating relatively high rates of infection and mortality. A third virus, the H5N1, responsible for avian influenza, has caused infection with some clinical similarities to those in ...

Abnormal immunity of non-survivors with COVID-19: predictors for mortality.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7396941
Infectious Diseases of Poverty; Zhao Y, Nie HX et. al.

Aug 4th, 2020 - The number of coronavirus disease 2019 (COVID-19) cases has rapidly increased all over the world. Specific information about immunity in non-survivors with COVID-19 is scarce. This study aimed to analyse the clinical characteristics and abnormal immunity of the confirmed COVID-19 non-survivors. In this single-centered, retrospective, observational study, we enrolled 125 patients with COVID-19 w...

Psychosocial factors associated with symptoms of generalized anxiety disorder in genera...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7401581
Journal of Investigative Medicine : the Official Publication of the American Federation for Clinical Research; Monterrosa-Castro A, Redondo-Mendoza V et. al.

Aug 4th, 2020 - Healthcare providers commonly experience symptoms of anxiety during public health crises and pandemics. The objective of the study was to identify the frequency of symptoms of generalized anxiety disorder (GAD) in general practitioners and to estimate the association with particular psychosocial and demographic factors. This is a cross-sectional study, where a total of 531 general practitioners...

Thoracic imaging of coronavirus disease 2019 (COVID-19) in children: a series of 91 cases.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7399600
Pediatric Radiology; Caro-Dominguez P, Shelmerdine SC et. al.

Aug 4th, 2020 - Pulmonary infection with SARS-CoV-2 virus (severe acute respiratory syndrome coronavirus 2; COVID-19) has rapidly spread worldwide to become a global pandemic. To collect paediatric COVID-19 cases worldwide and to summarize both clinical and imaging findings in children who tested positive on polymerase chain reaction testing for SARS-CoV-2. Data were collected by completion of a standardised c...

Initial Challenges of Caregiving During COVID-19: Caregiver Burden, Mental Health, and ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7398861
Child Psychiatry and Human Development; Russell BS, Hutchison M et. al.

Aug 4th, 2020 - Research confirms that the mental health burdens following community-wide disasters are extensive, with pervasive impacts noted in individuals and families. It is clear that child disaster outcomes are worst among children of highly distressed caregivers, or those caregivers who experience their own negative mental health outcomes from the disaster. The current study used path analysis to exami...

Five common skin manifestations of COVID-19 identified.
https://doi.org/10.1111/bjd.19204
The British Journal of Dermatology;

Aug 3rd, 2020 - COVID-19, also called coronavirus, is an infectious disease caused by SARS-CoV-2. First identified in December 2019, in March 2020 it was announced by the World Health Organisation that COVID-19 had become a global pandemic. The disease can affect different organ systems, and early reports have suggested skin symptoms. The researchers, working with dermatologists across Spain, reviewed 375 pati...

Antibody response against SARS-CoV-2 spike protein and nucleoprotein evaluated by 4 aut...
https://doi.org/10.1016/j.cmi.2020.07.038
Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases; Van Elslande J, Decru B et. al.

Aug 3rd, 2020 - To determine the antibody response against SARS-CoV-2 spike protein and nucleoprotein using 4 automated immunoassays and 3 ELISAs for the detection of total Ig antibodies (Roche) or IgG (Abbott, Diasorin, Snibe, Euroimmun, Mikrogen) in COVID-19 patients. Sensitivity and dynamic trend to seropositivity were evaluated in 233 samples from 114 patients with moderate, severe, or critical COVID-19 co...

Placental SARS-CoV-2 in a Pregnant Woman with Mild COVID-19 Disease.
https://doi.org/10.1002/jmv.26386
Journal of Medical Virology; Hsu AL, Guan M et. al.

Aug 3rd, 2020 - The full impact of COVID-19 on pregnancy remains uncharacterized. Current literature suggests minimal maternal, fetal, and neonatal morbidity and mortality.1 COVID-19 manifestations appear similar between pregnant and non-pregnant women.2 OBJECTIVES/STUDY DESIGN: We present a case of placental SARS-CoV-2 virus in a woman with mild COVID-19 disease, then review the literature. RT-PCR was perform...

Emergency management of 2019 novel coronavirus: implications for the dermatology depart...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7300445
The British Journal of Dermatology; Tao J, Song Z et. al.

Aug 3rd, 2020 - Since cases first emerged in December 2019, COVID-19 (a type of coronavirus) has rapidly become pandemic. This fast-tracked paper (published quickly) from China on COVID-19 is written by dermatologists at the epicentre of the outbreak in Wuhan. Dermatology clinic staff may be at risk because protective equipment is not routinely available, and skin lesions might possibly transmit the virus indi...

Comparing eating behaviours, and symptoms of depression and anxiety between Spain and G...
https://doi.org/10.1002/erv.2772
European Eating Disorders Review : the Journal of the Eating Disorders Association REFERENCES; Papandreou C, Arija V et. al.

Aug 3rd, 2020 - We compared eating behaviours, and depressive and anxiety symptoms in two countries with different confinement strictness strategies and different levels of COVID-19 pandemic. A web-based cross-sectional survey was administered during and shortly after the COVID-19 related lockdown in Spain and Greece. Multivariable linear regression analyses were performed to identify country differences assoc...

Does immunosuppressive treatment entail an additional risk for children with rheumatic ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7395897
Rheumatology International; Koker O, Demirkan FG et. al.

Aug 3rd, 2020 - The aim of the research was to further extend current knowledge of whether severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) disease 2019 (COVID-19) entails a risk for children with various rheumatic diseases under immunosuppressive treatment. Telephone survey was administered by conducting interviews with the parents from May 1, 2020 to May 20, 2020. A message containing a link to t...