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Lung Ultrasonography for the Diagnosis of SARS-CoV-2 Pneumonia in the Emergency Departm...
https://doi.org/10.1016/j.annemergmed.2020.10.008
Annals of Emergency Medicine; Pivetta E, Goffi A et. al.

Jan 19th, 2021 - Accurate diagnostic testing to identify severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is critical. Although highly specific, SARS-CoV-2 reverse transcriptase-polymerase chain reaction (RT-PCR) has been shown in clinical practice to be affected by a noninsignificant proportion of false-negative results. This study seeks to explore whether the integration of lung ultrason...

Clinical validation of a second generation anti-SARS-CoV-2 IgG and IgM automated chemil...
https://doi.org/10.1002/jmv.26809
Journal of Medical Virology; Pieri M, Nuccetelli M et. al.

Jan 19th, 2021 - SARS-CoV-2 infection has proven to be extremely contagious and has spread rapidly all over the world. A key aspect in limiting the virus diffusion is to ensure early and accurate diagnosis. Serological assays could be an alternative in increasing testing capabilities, particularly when used as part of an algorithmic approach combined with molecular analysis. The aim of this study was to evaluat...

Follow-up of SARS-CoV-2 Positive Subgroup from the Asymptomatic novel CORonavirus iNfec...
https://doi.org/10.1002/jmv.26810
Journal of Medical Virology; Meyers KJ, Dillman B et. al.

Jan 19th, 2021 - A nested longitudinal study within the Asymptomatic novel CORonavirus iNfection (ACORN) study followed participants with positive nasopharyngeal swab to query for development of symptoms and assess duration of positive RT-PCR test results. Of the 91 participants initially testing positive, 86 participated in follow-up approximately 14 days after study enrollment; of those 86 participants, 19 (2...

Programming course for health science as a strategy to engage students during the coron...
https://doi.org/10.1152/advan.00183.2020
Advances in Physiology Education; De la Fuente CI, Guadagnin EC et. al.

Jan 19th, 2021 - Programming is an important skill for different areas of knowledge. While in the past, programming skills were much more related to fields of computer sciences and engineering, today, professionals from different areas benefit from the ability to write codes for different applications. Furthermore, programming stimulates logical thinking, which impacts other personal abilities. Health science s...

Association of Intensive Care Unit Patient Load and Demand With Mortality Rates in US D...
https://doi.org/10.1001/jamanetworkopen.2020.34266
JAMA Network Open; Bravata DM, Perkins AJ et. al.

Jan 19th, 2021 - Although strain on hospital capacity has been associated with increased mortality in nonpandemic settings, studies are needed to examine the association between coronavirus disease 2019 (COVID-19) critical care capacity and mortality. To examine whether COVID-19 mortality was associated with COVID-19 intensive care unit (ICU) strain. This cohort study was conducted among veterans with COVID-19,...

COVID-19-related Potential Multisystem Inflammatory Syndrome in Childhood in a Neonate ...
https://doi.org/10.1097/INF.0000000000003054
The Pediatric Infectious Disease Journal; Khaund Borkotoky R, Banerjee Barua P et. al.

Jan 19th, 2021 - A term infant with persistent pulmonary hypertension of newborn developed clinical and laboratory features of multisystem inflammatory syndrome in childhood (MIS-C) between days 12 and 14. Mother and baby were anti-SARS-Coronavirus-2 (SARS-CoV-2) IgG positive and anti-SARS-CoV-2 IgM negative on day 18, with negative COVID-19 PCR on repeated testing; possible first documentation of neonatal MIS-...

Case series of 20 pregnant women with 2019 novel coronavirus disease in Wuhan, China.
https://doi.org/10.1111/jog.14664
The Journal of Obstetrics and Gynaecology Research; Guo Y, Yuan J et. al.

Jan 19th, 2021 - To evaluate perinatal outcomes regarding clinical presentation in pregnancy and the vertical transmission potential of COVID-19. Clinical records, laboratory findings, and chest computed tomography (CT) scans were retrospectively reviewed from 20 pregnant patients with laboratory-confirmed COVID-19 who were admitted to Renmin Hospital of Wuhan University and The Third Hospital of Wuhan, from Ja...

Development of a large spontaneous pneumothorax after recovery from mild COVID-19 infec...
https://doi.org/10.1136/bcr-2020-238863
BMJ Case Reports; Nunna K, Braun AB

Jan 19th, 2021 - A previously healthy 37-year-old man presented with fevers and myalgias for a week with a minimal dry cough. Initial SARS-CoV-2 nasopharyngeal testing was negative, but in light of high community prevalence, he was diagnosed with COVID-19, treated with supportive care and self-quarantined at home. Three days after resolution of all symptoms, he developed sudden onset chest pain. Chest imaging r...

COVID-19 restrictions and changing sexual behaviours in HIV-negative MSM at high risk o...
https://doi.org/10.1136/sextrans-2020-054768
Sexually Transmitted Infections; Hyndman I, Nugent D et. al.

Jan 19th, 2021 - The COVID-19 pandemic and its related restrictions have affected attendance to and delivery of UK sexual healthcare services (SHS). We surveyed the impact on sexual behaviour of men having sex with men (MSM) to inform future SHS provision. We conducted a cross-sectional, anonymous, web-based survey among HIV-negative MSM at high risk of HIV infection who attended 56 Dean Street, a sexual health...

Coronavirus (COVID-19) Update: January 19, 2021 | FDA
https://www.fda.gov/news-events/press-announcements/coronavirus-covid-19-update-january-19-2021

Jan 19th, 2021 - For Immediate Release: January 19, 2021 The U.S. Food and Drug Administration today announced the following actions taken in its ongoing response effort to the COVID-19 pandemic: Today, to help protect consumers from methanol poisoning, the FDA issued a new guidance, “Policy for Testing of Alcohol (Ethanol) and Isopropyl Alcohol for Methanol, Including During the Public Health Emergency (COVID-...

SARS-CoV-2 Antigen Rapid Immunoassay for Diagnosis of COVID-19 in the Emergency Departm...
https://doi.org/10.1080/1354750X.2021.1876769
Biomarkers : Biochemical Indicators of Exposure, Response... Möckel M, Corman VM et. al.

Jan 18th, 2021 - In the emergency department (ED) setting, rapid testing for SARS-CoV-2 is likely associated with advantages to patients and healthcare workers, for example enabling early but rationale use of limited isolation resources. Most recently, several SARS-CoV-2 rapid point-of-care antigen tests (AGTEST) became available. There is a growing need for data regarding their clinical utility and performance...

Comparison of Fit for Sealed and Loose-Fitting Surgical Masks and N95 Filtering Facepie...
https://doi.org/10.1093/annweh/wxaa125
Annals of Work Exposures and Health; Karuppasamy K, Obuchowski N

Jan 18th, 2021 - N95 filtering facepiece respirators (N95 FFRs) and surgical masks are comprised of multiple layers of nonwoven polypropylene. Tight-fitting N95 FFRs are respiratory protective devices (RPDs) designed to efficiently filter aerosols. During the COVID-19 pandemic, health care workers (HCWs) throughout the world continue to face shortages of disposable N95 FFRs. Existing version of widely available...

Population-based Estimates of COVID-19-like Illness, COVID-19 Illness, and Rates of Cas...
https://doi.org/10.1093/cid/ciab038
Clinical Infectious Diseases : an Official Publication Of... Alroy KA, Crossa A et. al.

Jan 18th, 2021 - Using a population-based, representative telephone survey, ~930,000 New York City residents had COVID-19 illness beginning March 20-April 30, 2020, a period with limited testing. For every 1000 persons estimated with COVID-19 illness, 141.8 were tested and reported as cases, 36.8 were hospitalized, and 12.8 died, varying by demographic characteristics.

Infographic. COVID-19 RT-PCR testing for elite athletes.
https://doi.org/10.1136/bjsports-2020-103751
British Journal of Sports Medicine; Rankin A, Massey A et. al.

Jan 18th, 2021 - Infographic. COVID-19 RT-PCR testing for elite athletes.|2021|Rankin A,Massey A,Falvey ÉC,Ellenbecker T,Harcourt P,|

Many EM Docs Have Treated COVID Patients Without Proper PPE: Survey
https://www.medscape.com/viewarticle/944351

Jan 18th, 2021 - Editor's note: Find the latest COVID-19 news and guidance in Medscape's Coronavirus Resource Center. Many emergency medicine (EM) physicians who responded to a Medscape survey said they have treated COVID-19 patients without appropriate personal protective equipment (PPE). In the Medscape Emergency Medicine Physicians' COVID-19 Experience Report, 21% of respondents said that that was sometimes ...

Rapid COVID Testing Is Not Where It Needs to Be
https://www.medscape.com/viewarticle/943512

Jan 18th, 2021 - This transcript has been edited for clarity. Robert D. Glatter, MD: Hi and welcome. I'm Dr Robert Glatter, medical advisor for Medscape Emergency Medicine. COVID-19 has killed more than 320,000 Americans so far. What was evident from the outset of the pandemic was the lack of a clear national policy and strategy related to testing as a way to reduce transmission of the virus. Here to discuss th...

FDA's Commitment to COVID Testing
https://www.medscape.com/viewarticle/944230

Jan 18th, 2021 - As we start a new year, it is important to pause and reflect on what a challenging year 2020 was for so many — one that was filled with heartbreak and uncertainty due to a pandemic, the likes of which have not been seen in our lifetime. As we remember the difficulties we've faced, and the challenges that remain, we would be remiss not to acknowledge the incredible scientific achievements that h...

Multivalent Nanobodies Block Coronavirus, Even When It Mutates
https://www.medscape.com/viewarticle/944260

Jan 18th, 2021 - (Reuters) - Combining small antibodies called nanobodies into single molecules to block the novel coronavirus may be more effective than targeting it with conventional antibodies or single nanobodies, according to a new study. These multivalent nanobodies "are substantially better in neutralizing viruses" and preventing them from breaking into cells, study leaders Florian Schmidt and Paul-Alber...

Top 10 Advances in Thoracic Oncology in 2020
https://www.medscape.com/viewarticle/944131

Jan 18th, 2021 - This transcript has been edited for clarity. Hello. It's Mark Kris from Memorial Sloan Kettering, here to give my top 10 developments in thoracic oncology in the year 2020. Lord, it's been a crazy year. We have all been mightily distracted by the COVID pandemic, but I don't want to lose sight of the important developments that happened last year in the field of thoracic oncology. #10: Agents fo...

Inter-laboratory Agreement of Anti-Severe Acute Respiratory Syndrome Coronavirus-2 (SAR...
https://doi.org/10.5858/arpa.2020-0811-SA
Archives of Pathology & Laboratory Medicine; Tacker DH, Bashleben C et. al.

Jan 18th, 2021 - - Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is a recently emerged, currently pandemic virus, and the etiological agent of coronavirus disease 2019 (COVID-19). Clinical testing for antibodies to SARS-CoV-2 has rapidly become widespread, but data regarding the inter-laboratory performance of these serologic assays are limited. - To describe the development and initial results o...