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Quantitative comparison of SARS-CoV-2 nucleic acid amplification test and antigen testi...
https://doi.org/10.1186/s12889-021-12489-8 10.15585/mmwr.mm695152a3 10.15585/mmwr.mm7003e3 10.1093/cid/ciab110 10.1016/S2468-2667(21)00002-5 10.1038/s41598-021-94055-1 10.7326/M20-1495 10.2807/1560-7917.ES.2020.25.32.2001483
BMC Public Health; Salvatore PP, Shah MM et. al.

Jan 15th, 2022 - Antigen tests for SARS-CoV-2 offer advantages over nucleic acid amplification tests (NAATs, such as RT-PCR), including lower cost and rapid return of results, but show reduced sensitivity. Public health organizations recommend different strategies for utilizing NAATs and antigen tests. We sought to create a framework for the quantitative comparison of these recommended strategies based on their...

Saliva-Based, COVID-19 RT-PCR Pooled Screening Strategy to Keep Schools Open.
https://doi.org/10.1017/dmp.2021.337
Disaster Medicine and Public Health Preparedness; Perea S, Tretina K et. al.

Jan 15th, 2022 - As of March 2020, governments throughout the world implemented business closures, work from home policies, and school closures due to exponential increase of coronavirus disease 2019 (COVID-19) cases, leaving only essential workers being able to work on site. For most of the children and adolescent school closures during the first lockdown had significant physical and psychosocial consequences....

Sexual Health and the Pandemic Crisis: Testing the Role of Psychological Vulnerability/...
https://doi.org/10.1007/s10508-021-02209-z 10.1037/bul0000157 10.1080/02674658808407714 10.1001/jamapsychiatry.2017.2164 10.1177/2167702613505532 10.1258/ijsa.2008.008468 10.1111/j.1743-6109.2010.02080.x 10.1016/S0140-6736(20)30460-8 10.1016/j.jsxm.2016.01.019 10.1037/a0016608 10.1016/j.jsxm.2021.04.007 10.1111/j.1743-6109.2009.01568.x 10.1111/j.1743-6109.2010.02156.x 10.1016/j.jsxm.2020.05.024 10.1038/s41443-020-0305-x 10.1111/jsm.12735 10.1080/03610910701539617 10.1016/j.jcbs.2020.09.010 10.1002/sm2.60 10.1080/00926230290001448 10.1192/bjp.118.547.593 10.1207/s15327752jpa5703_4 10.1080/00224499.2016.1269306 10.1080/00224499.2015.1063576 10.1080/0092623X.2017.1405304 10.1007/s10508-020-01742-7 10.1111/j.1743-6109.2008.00800.x 10.1111/j.1743-6109.2005.20356.x 10.1016/s0165-0327(99)00050-6 10.1037/a0020327 10.1038/sj.ijir.3901250 10.1016/j.jsxm.2020.04.380 10.1016/s0191-8869(03)00118-1 10.1080/00926230701267852 10.1016/j.jsxm.2020.10.008 10.1007/s10508-013-0180-3 10.1038/s41443-018-0105-8 10.1016/j.jsxm.2017.11.227 10.1016/j.sexol.2018.09.003 10.1080/00926230903065716 10.1111/J.1743-6109.2009.01656.X 10.1080/1468199031000061281 10.1080/00926230802096358 10.1080/00224490609552300 10.1016/j.cpr.2013.04.003 10.1016/j.jsxm.2017.01.021 10.1111/jsm.12666 10.1080/0092623x.2014.985352 10.1111/j.1743-6109.2011.02467.x 10.1111/j.1743-6109.2010.02092.x 10.1037/bul0000088 10.3389/fpsyg.2020.01540 10.1007/978-3-030-16785-1_9 10.1080/009262300278597 10.1016/S0090-4295(97)00238-0 10.1080/00224498109551107 10.3389/fpsyg.2020.01958 10.1017/s0033291720000975 10.1007/bf01542114 10.1016/j.jsxm.2020.06.006 10.1016/j.jsxm.2020.07.085 10.1002/per.808 10.1002/per.1885 10.1016/j.jpsychires.2018.04.017 10.1002/ijgo.13193 10.1037/0021-843x.105.2.181
Archives of Sexual Behavior; Nobre P, Rosa PJ et. al.

Jan 15th, 2022 - Recent findings suggest that the current COVID-19 pandemic has a potential negative impact in several areas of life, including sexual health. However, less is known about the psychological dimensions that may work as vulnerability/protective factors for the development of sexual problems in the current pandemic. The current study used a longitudinal design to examine the role played by personal...

Effect of Subcutaneous Casirivimab and Imdevimab Antibody Combination vs Placebo on Dev...
https://doi.org/10.1001/jama.2021.24939
JAMA O'Brien MP, Forleo-Neto E et. al.

Jan 15th, 2022 - Easy-to-administer anti-SARS-CoV-2 treatments may be used to prevent progression from asymptomatic infection to symptomatic disease and to reduce viral carriage. To evaluate the effect of combination subcutaneous casirivimab and imdevimab on progression from early asymptomatic SARS-CoV-2 infection to symptomatic COVID-19. Randomized, double-blind, placebo-controlled, phase 3 trial of close hous...

SARS-CoV-2 Gastrointestinal Shedding in Hospitalized Children.
https://doi.org/10.1542/hpeds.2021-006304
Hospital Pediatrics; Tam I, McNamara C et. al.

Jan 15th, 2022 - Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a respiratory virus that can cause gastrointestinal (GI) symptoms, with studies demonstrating detection of stool viral RNA weeks after respiratory tract clearance. It is unknown if children who test negative for SARS-CoV-2 on a nasopharyngeal (NP) swab may be shedding the virus in their stool. To measure the prevalence of SARS-CoV-...

Brain Injury Biomarkers Elevated in Hospitalized COVID Patients
https://www.medpagetoday.com/neurology/generalneurology/96699

Jan 14th, 2022 - Hospitalized patients with COVID-19 and no prior history of dementia had elevated levels of brain injury biomarkers, an observational study showed. Blood levels of total tau (t-tau), phosphorylated tau181 (p-tau181), glial fibrillary acidic protein (GFAP), and neurofilament light (NfL) were significantly elevated in COVID-19 patients with encephalopathy and those who died in the hospital, repor...

FDA Roundup: January 14, 2022 | FDA
https://www.fda.gov/news-events/press-announcements/fda-roundup-january-14-2022

Jan 14th, 2022 - For Immediate Release: January 14, 2022 Today, the U.S. Food and Drug Administration is providing an at-a-glance summary of news from around the agency: Today, the Interagency Food Safety Analytics Collaboration — a collaboration between the Centers for Disease Control and Prevention, the U.S. Food and Drug Administration, and the Food Safety and Inspection Service — has published its prioritie...

Evaluation of SARS-CoV-2 entry, inflammation and new therapeutics in human lung tissue ...
https://doi.org/10.1371/journal.ppat.1010171
PLoS Pathogens; Grau-Expósito J, Perea D et. al.

Jan 14th, 2022 - The development of physiological models that reproduce SARS-CoV-2 infection in primary human cells will be instrumental to identify host-pathogen interactions and potential therapeutics. Here, using cell suspensions directly from primary human lung tissues (HLT), we have developed a rapid platform for the identification of viral targets and the expression of viral entry factors, as well as for ...

Focal Peripheral Neuropathies Observed in Patients Diagnosed With COVID-19: A Case Series.
https://doi.org/10.1097/PHM.0000000000001924
American Journal of Physical Medicine & Rehabilitation; Liu EA, Salazar T et. al.

Jan 14th, 2022 - A growing number of studies have documented a wide variety of neurological manifestations associated with the novel SARS-CoV-2 (COVID-19). Of the available literature, cranial neuropathies and central nervous system disorders, such as encephalopathy and ischemic strokes, remain the predominant discussion. Limited investigations exist examining peripheral neuropathies of those with COVID-19. Thi...

Aging-related cell type-specific pathophysiologic immune responses that exacerbate dise...
https://doi.org/10.1111/acel.13544
Aging Cell; Hou Y, Zhou Y et. al.

Jan 14th, 2022 - Coronavirus disease 2019 (COVID-19) is especially severe in aged patients, defined as 65 years or older, for reasons that are currently unknown. To investigate the underlying basis for this vulnerability, we performed multimodal data analyses on immunity, inflammation, and COVID-19 incidence and severity as a function of age. Our analysis leveraged age-specific COVID-19 mortality and laboratory...

COVID-19 Testing Among US Children, Parental Preferences for Testing Venues, and Accept...
https://doi.org/10.1177/00333549211065518
Public Health Reports (Washington, D.C. : 1974); Teasdale CA, Borrell LN et. al.

Jan 14th, 2022 - Testing remains critical for identifying pediatric cases of COVID-19 and as a public health intervention to contain infections. We surveyed US parents to measure the proportion of children tested for COVID-19 since the start of the pandemic, preferred testing venues for children, and acceptability of school-based COVID-19 testing. We conducted an online survey of 2074 US parents of children age...

COVID-19 Cluster Linked to Aerosol Transmission of SARS-CoV-2 via Floor Drains.
https://doi.org/10.1093/infdis/jiab598
The Journal of Infectious Diseases; Han T, Park H et. al.

Jan 14th, 2022 - Recently, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission through exposure to aerosols has been suggested. Therefore, we investigated the possibility of aerosol SARS-CoV-2 transmission within an apartment complex where residents reported testing positive for SARS-CoV-2 despite having no direct contact with other SARS-CoV-2-infected people. Information on symptom onset ...

Estimation of Underreported Cases of Infections and Deaths from COVID-19 for Countries ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8743622
Journal of Environmental and Public Health; Devkota JU

Jan 14th, 2022 - COVID-19 pandemic has overburdened the public healthcare system around the world. Further, lockdown imposed to curb the spread of pandemic has shown to have an adverse effect on economic and health status of an individual. It has also compelled us to switch from the physical world to virtual world, thus depriving us of benefits of person-to-person direct contact. People from developing countrie...

Correlates of Coronavirus Disease 2019 (COVID-19) Vaccine Hesitancy Among People Who In...
https://doi.org/10.1093/cid/ciab975
Clinical Infectious Diseases : an Official Publication Of... Strathdee SA, Abramovitz D et. al.

Jan 14th, 2022 - People who inject drugs (PWID) are vulnerable to acquiring severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). We examined correlates of coronavirus disease 2019 (COVID-19) vaccine hesitancy among PWID in the US-Mexico border region, of whom only 7.6% had received ≥ 1 COVID-19 vaccine dose by September 2021. Between October 2020 and September 2021, participants aged ≥ 18 years from Sa...

COVID-19 Vaccination and Communicable Disease Testing Services' Integration Within a Sy...
https://doi.org/10.1097/JNC.0000000000000322
The Journal of the Association of Nurses in AIDS Care : J... Heidari O, Meyer D et. al.

Jan 14th, 2022 - People who inject drugs often have a higher prevalence of risk factors associated with coronavirus disease 2019 (COVID-19) infection and associated morbidity and mortality, compounded by challenges in health care access. This increased vulnerability underscores the critical need to prioritize people who inject drug in ongoing COVID-19 vaccination efforts. Co-location of syringe services, COVID-...

Notes from the Field: HIV Outbreak During the COVID-19 Pandemic Among Persons Who Injec...
https://doi.org/10.15585/mmwr.mm7102a4
MMWR. Morbidity and Mortality Weekly Report; Hershow RB, Wilson S et. al.

Jan 14th, 2022 - During October 2019, the West Virginia Bureau for Public Health (WVBPH) noted that an increasing number of persons who inject drugs (PWID) in Kanawha County received a diagnosis of HIV. The number of HIV diagnoses among PWID increased from less than five annually during 2016-2018 to 11 during January-October 2019 (Figure). Kanawha County (with an approximate population of 180,000*) has high rat...

Quantitative CT imaging features for COVID-19 evaluation: The ability to differentiate ...
https://doi.org/10.1371/journal.pone.0256194
PloS One; Peng S, Pan L et. al.

Jan 14th, 2022 - COVID-19 and Non-Covid-19 (NC) Pneumonia encountered high CT imaging overlaps during pandemic. The study aims to evaluate the effectiveness of image-based quantitative CT features in discriminating COVID-19 from NC Pneumonia. 145 patients with highly suspected COVID-19 were retrospectively enrolled from four centers in Sichuan Province during January 23 to March 23, 2020. 88 cases were confirme...

An international, interlaboratory ring trial confirms the feasibility of an extraction-...
https://doi.org/10.1371/journal.pone.0261853
PloS One; Mills MG, Bruce E et. al.

Jan 14th, 2022 - Reverse transcription-quantitative polymerase chain reaction (RT-qPCR) is used worldwide to test and trace the spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). "Extraction-less" or "direct" real time-reverse transcription polymerase chain reaction (RT-PCR) is a transparent and accessible qualitative method for SARS-CoV-2 detection from nasopharyngeal or oral pharyngeal sa...

Development and validation of a multi-lingual online questionnaire for surveying the CO...
https://doi.org/10.1186/s12889-022-12500-w
BMC Public Health; Ingram C, Chen Y et. al.

Jan 14th, 2022 - Despite widespread COVID-19 vaccination programs, there is an ongoing need for targeted disease prevention and control efforts in high-risk occupational settings. This study aimed to develop, pilot, and validate an instrument for surveying occupational COVID-19 infection prevention and control (IPC) measures available to workers in diverse geographic and occupational settings. A 44-item online ...

Update to COVID-19 serologic testing : FAQs and caveats.
https://doi.org/10.3949/ccjm.87a.20054-up
Cleveland Clinic Journal of Medicine; Kadkhoda K

Jan 14th, 2022 - Update to COVID-19 serologic testing : FAQs and caveats.|2022|Kadkhoda K,|