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International Sexual Health And REproductive health (I-SHARE) survey during COVID-19: s...
https://doi.org/10.1136/sextrans-2020-054664
Sexually Transmitted Infections; Michielsen K, Larrson EC et. al.

Oct 21st, 2020 - COVID-19 may have a profound impact on sexual health, reproductive health and social life across the world. Shelter in place regulations that have extended across the globe may influence condomless sex, exacerbate intimate partner violence and reduce access to essential reproductive health services. Population representative research is challenging during shelter in place, leaving major gaps in...

Management Trends in the Cath Lab During the COVID-19 Period, an Egyptian Survey.
https://doi.org/10.1016/j.cpcardiol.2020.100715
Current Problems in Cardiology; Mahmoud SED, Etriby SE et. al.

Oct 21st, 2020 - The World Health Organization (WHO) announced that the novel coronavirus pneumonia pandemic caused by SARS-CoV-2 was classified as a public health emergency of international concern on January 30, 2020 Egypt's health ministry had announced the first case in the country at Cairo International Airport involving a Chinese national on 14 February 2020. Case decisions in the cath labs should be indi...

Commercial Serology Assays Predict Neutralization Activity Against SARS-CoV-2.
https://doi.org/10.1093/clinchem/hvaa262
Clinical Chemistry; Suhandynata RT, Hoffman MA et. al.

Oct 21st, 2020 - It is unknown whether a positive serology result correlates with protective immunity against SARS-CoV-2. There are also concerns regarding the low positive predictive value of SARS-CoV-2 serology tests, especially when testing populations with low disease prevalence. A neutralization assay was validated in a set of PCR confirmed positive specimens and in a negative cohort. In addition, 9,530 sp...

Intricacies in characterizing positivity in pooled sample testing for SARS-CoV-2.
https://doi.org/10.1002/jmv.26618
Journal of Medical Virology; Mohanty S, Ravindra A et. al.

Oct 21st, 2020 - The unprecedented demand for testing for the ongoing coronavirus disease-2019 (COVID-19) pandemic caused by SARS-CoV-2 has led to an acute shortage and limited availability of test reagents for which pooling of samples has been recommended in areas with low prevalence. Considering the possibility of dilution factor in pool testing, an attempt was made to find out possibility of any true positiv...

A systematic review of etiology, epidemiology, clinical manifestations, image findings,...
https://doi.org/10.1097/MD.0000000000022688
Medicine Xu J, Ma XP et. al.

Oct 21st, 2020 - Unknown origin pneumonia has been furiously spreading since the late of December 2019, subsequently spread to approximately all provinces and areas in China and many countries, which was announced as a Public Health Emergency of International Concern by World Health Organization (WHO). The studies on 2019 Corona Virus Disease-19 (COVID-19) conducted from various fields around the world. Herein,...

Lessons Learned from Battling COVID-19: The Korean Experience.
https://doi.org/10.3390/ijerph17207548
International Journal of Environmental Research and Public Health; Lee SM, Lee D

Oct 21st, 2020 - The COVID-19 pandemic has swept the world like a gigantic tsunami, turning social and economic activities upside down. This paper presents some of the innovative response strategies implemented by the public health system, healthcare facilities, and government in South Korea, which has been hailed as the model country for its success in containing COVID-19. Korea reinvented its public health in...

A model based on CT radiomic features for predicting RT-PCR becoming negative in corona...
https://doi.org/10.1186/s12880-020-00521-z
BMC Medical Imaging; Cai Q, Du SY et. al.

Oct 21st, 2020 - Coronavirus disease 2019 (COVID-19) has emerged as a global pandemic. According to the diagnosis and treatment guidelines of China, negative reverse transcription-polymerase chain reaction (RT-PCR) is the key criterion for discharging COVID-19 patients. However, repeated RT-PCR tests lead to medical waste and prolonged hospital stays for COVID-19 patients during the recovery period. Our purpose...

Detecting SARS-CoV-2 at point of care: preliminary data comparing loop-mediated isother...
https://doi.org/10.1186/s12879-020-05484-8
BMC Infectious Diseases; Österdahl MF, Lee KA et. al.

Oct 21st, 2020 - A cost effective and efficient diagnostic tool for COVID-19 as near to the point of care (PoC) as possible would be a game changer in the current pandemic. We tested reverse transcription loop mediated isothermal amplification (RT-LAMP), a method which can produce results in under 30 min, alongside standard methods in a real-life clinical setting. This prospective service improvement project pi...

Projected utility of pharmacogenomic testing among individuals hospitalized with COVID-...
https://doi.org/10.1111/cts.12919
Clinical and Translational Science; Stevenson JM, Alexander GC et. al.

Oct 21st, 2020 - Many academic institutions are collecting blood samples from patients seeking treatment for COVID-19 to build research biorepositories. It may be feasible to extract pharmacogenomic information from biorepositories for clinical use. We sought to characterize the potential value of multi-gene pharmacogenomic testing among individuals hospitalized with COVID-19 in the United States. We performed ...

Delayed Time to Cryptosporidiosis in Bangladeshi Children is Associated with Greater Fe...
https://doi.org/10.4269/ajtmh.20-0657
The American Journal of Tropical Medicine and Hygiene; Steiner JZ, Kabir M et. al.

Oct 20th, 2020 - Italy has been one of the most severely affected countries by the COVID-19 pandemic, and the case fatality rate (CFR) estimated based on Italian data is one of the highest worldwide. We analyzed public data from the first 50 days of the epidemic in Italy (from February 24 to April 13, 2020) to evaluate whether evolving testing strategies and capacity could account for trends in the CFR. The CFR...

Drive-through transcutaneous bilirubin screening for neonatal jaundice: A safe and effi...
https://doi.org/10.1111/jpc.15226
Journal of Paediatrics and Child Health References; Chua BS, Song LH et. al.

Oct 20th, 2020 - The coronavirus disease 2019 (COVID-19) cases was on an increasing trend, including in Malaysia. The Malaysian Ministry of Health had implemented a range of measures, such as the use of masks and social distancing, to reduce the risk of transmission. Traditionally, newborns are evaluated for neonatal jaundice using visual assessment, a capillary heel prick and serum bilirubin (SB) sampling in p...

New HIV diagnoses in patients with COVID-19: two case reports and a brief literature re...
https://doi.org/10.1186/s12879-020-05480-y
BMC Infectious Diseases; Zhang JC, Yu XH et. al.

Oct 20th, 2020 - COVID-19 is novel infectious disease with an evolving understanding of its epidemiology and clinical manifestations. Severe cases developed life-threatening complications, such as respiratory failure, shock, and multiple organs dysfunction. Immunocompromised patients often present atypical presentations of viral infected diseases. We report newly diagnosed HIV infections in two patients with CO...

Chronic exposure to ambient particulate matter induces gut microbial dysbiosis in a rat...
https://doi.org/10.1186/s12931-020-01529-3
Respiratory Research; Li N, Yang Z et. al.

Oct 20th, 2020 - Technology can enable syringe service programs (SSPs) and other community-based organizations (CBOs) operating under a harm reduction framework to work with an increased number of clients and can also enable organizations to offer services more effectively (e.g., offering HIV testing in ways participants may be more likely to accept). In the current time of COVID-19 social distancing, technolog...

Don't make the best of it, make it better: Matching to residency programs during COVID-19.
https://doi.org/10.1017/cjn.2020.236
The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques; Moore F, Bouhadoun S et. al.

Oct 20th, 2020 - Transmission of SARS-CoV-2 has significant implications for hospital infection prevention and control, discharge management, and public health. We reviewed available literature to reach an evidenced-based consensus on the expected duration of viral shedding. We queried four scholarly repositories/search engines for studies reporting SARS-CoV-2 viral shedding dynamics by PCR and/or culture avail...

Association of TERT and DSP variants with microscopic polyangiitis and myeloperoxidase-...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7470719
Arthritis Research & Therapy; Kawasaki A, Namba N et. al.

Oct 20th, 2020 - There are currently no studies that have examined whether one dosage can be uniformly applied to different respirator types to effectively decontaminate SARS-CoV-2 on N95 filtering facepiece respirators (FFRs). Health care workers have been using this disinfection method during the pandemic. Our objective was to determine the effect of UVC on SARS-CoV-2 inoculated N95 respirators and whether th...

Recurrent urothelial carcinoma-like FGFR3 genomic alterations in malignant Brenner tumo...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7467868
Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc; Lin DI, Killian JK et. al.

Oct 20th, 2020 - The ongoing global pandemic of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has led to active research in its associated diagnostics and medical treatments. While quantitative reverse transcription polymerase chain reaction (qRT-PCR) is the most reliable method to detect viral genes of SARS-CoV-2, serological tests for specific antiviral antibodies are also important as they ide...

Toward a human-centered use of technology: a stakeholder analysis of harm reduction and...
https://doi.org/10.1186/s12954-020-00422-y
Harm Reduction Journal; Aronson ID, Bennett AS et. al.

Oct 20th, 2020 - Technology can enable syringe service programs (SSPs) and other community-based organizations (CBOs) operating under a harm reduction framework to work with an increased number of clients and can also enable organizations to offer services more effectively (e.g., offering HIV testing in ways participants may be more likely to accept). In the current time of COVID-19 social distancing, technolog...

Proposed clinical indicators for efficient screening and testing for COVID-19 infection...
https://doi.org/10.1080/21645515.2020.1822135
Human Vaccines & Immunotherapeutics; Zimmerman RK, Nowalk MP et. al.

Oct 20th, 2020 - The introduction and rapid transmission of SARS-CoV-2 in the United States resulted in methods to assess, mitigate, and contain the resulting COVID-19 disease derived from limited knowledge. Screening for testing has been based on symptoms typically observed in inpatients, yet outpatient symptoms may differ. Classification and regression trees recursive partitioning created a decision tree clas...

COVID-19-Associated Coagulopathy and Inflammatory Response: What Do We Know Already and...
https://doi.org/10.1213/ANE.0000000000005147
Anesthesia and Analgesia; Görlinger K, Dirkmann D et. al.

Oct 20th, 2020 - Patients with coronavirus disease 2019 (COVID-19) frequently experience a coagulopathy associated with a high incidence of thrombotic events leading to poor outcomes. Here, biomarkers of coagulation (such as D-dimer, fibrinogen, platelet count), inflammation (such as interleukin-6), and immunity (such as lymphocyte count) as well as clinical scoring systems (such as sequential organ failure ass...

Proteins associated with neutrophil degranulation are upregulated in nasopharyngeal swa...
https://doi.org/10.1371/journal.pone.0240012
PloS One; Akgun E, Tuzuner MB et. al.

Oct 20th, 2020 - COVID-19 or severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) appeared throughout the World and currently affected more than 9 million people and caused the death of around 470,000 patients. The novel strain of the coronavirus disease is transmittable at a devastating rate with a high rate of severe hospitalization even more so for the elderly population. Naso-oro-pharyngeal swab sam...