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Osteoporosis Drugs Don't Worsen COVID-19 Risk, May Help
https://www.medscape.com/viewarticle/941110

Nov 16th, 2020 - Editor's note: Find the latest COVID-19 news and guidance in Medscape's Coronavirus Resource Center. New observational data are the first to support recommendations to continue osteoporosis medications during the COVID-19 pandemic, and even suggest that some agents may protect against the virus.  Findings from the cross-sectional study of 2102 patients with osteoporosis, osteoarthritis, and/or ...

Osteoporosis Drugs Don't Worsen COVID-19 Risk, May Help
https://www.staging.medscape.com/viewarticle/941110

Nov 16th, 2020 - Editor's note: Find the latest COVID-19 news and guidance in Medscape's Coronavirus Resource Center. New observational data are the first to support recommendations to continue osteoporosis medications during the COVID-19 pandemic, and even suggest that some agents may protect against the virus.  Findings from the cross-sectional study of 2102 patients with osteoporosis, osteoarthritis, and/or ...

Why Not Try Melatonin, Zinc, Vit C? COVID-19 and Pascal's Wager
https://www.medscape.com/viewarticle/941041

Nov 16th, 2020 - Find the latest COVID-19 news and guidance in Medscape's Coronavirus Resource Center. This transcript has been edited for clarity. Welcome to Impact Factor, your weekly dose of commentary on a new medical study. I'm Dr F. Perry Wilson from the Yale School of Medicine. Things are getting a bit bleak here in New Haven. Although my hospital has not reached the peak we saw in April, with 450 COVID-...

Vitamin D Deficiency Is Inversely Associated with COVID-19 Incidence and Disease Severi...
https://doi.org/10.1093/jn/nxaa332
The Journal of Nutrition; Luo X, Liao Q et. al.

Nov 14th, 2020 - Vitamin D might have beneficial potential in influencing the natural history of the coronavirus disease 2019 (COVID-19) due to its immunomodulatory and anti-inflammatory properties. The aim was to investigate whether vitamin D deficiency is associated with COVID-19 incidence and disease severity in Chinese people. In a cross-sectional study we retrospectively analyzed 335 COVID-19 patients (med...

Vitamin D 25OH deficiency in COVID-19 patients admitted to a tertiary referral hospital.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7605851
Clinical Nutrition (Edinburgh, Scotland); Cereda E, Bogliolo L et. al.

Nov 14th, 2020 - Great interest has been raised by the possible protective role of vitamin D in coronavirus disease 2019 (COVID-19), but objective data on 25(OH)vitamin D deficiency in hospitalized COVID-19 patients are not conclusive. The aim of this study was to determine the prevalence of 25(OH)vitamin D deficiency in COVID-19 patients admitted to an Italian referral hospital and explore its association with...

Correlation between premorbid IL-6 levels and COVID-19 mortality: Potential role for Vi...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7486051
International Immunopharmacology; Silberstein M

Nov 13th, 2020 - There is recent evidence that interleukin-6 (IL-6) levels are elevated in cases of complicated COVID-19, but it is also possible that this cytokine may have a far more important role in the pathogenesis of viral infection. IL-6 is known to be modulated by Vitamin D, and there is preliminary evidence that deficiency of this vitamin is linked to poorer outcomes. To identify whether IL-6 levels pr...

Lower levels of vitamin D are associated with SARS-CoV-2 infection and mortality in the...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7489890
International Immunopharmacology; Padhi S, Suvankar S et. al.

Nov 13th, 2020 - The role of vitamin D in the susceptibility and severity of various viral diseases has been well documented. Recently, some reports highlighted the possible importance of vitamin D in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Although India receives adequate sunlight throughout the year, the majority of Indians are deficient in vitamin D levels. In the present study, we hypo...

Prevalence of obesity and hypovitaminosis D in elderly with severe acute respiratory sy...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7552968
Clinical Nutrition ESPEN; Gonçalves TJM, Gonçalves SEAB et. al.

Nov 13th, 2020 - Verify the prevalence of hypovitaminosis D and obesity in elderly patients infected by new coronavirus. The patients developed severe symptoms and were admitted in intensive care unit (ICU) to receive invasive ventilation due to diagnosis of acute respiratory distress syndrome (ARDS). A cross-sectional descriptive study composed of elderly (age ≥ 60 years) admitted to the ICU. Were collected de...

SARS-CoV-2: Influence of phosphate and magnesium, moderated by vitamin D, on energy (AT...
https://doi.org/10.1152/ajpendo.00474.2020
American Journal of Physiology. Endocrinology and Metabolism; van Kempen TA, Deixler E

Nov 11th, 2020 - The use of vitamin D to reduce the severity of COVID-19 complications is receiving considerable attention, backed by encouraging data. Its purported mode of action is as an immune modulator. Vitamin D, however, also affects metabolism of phosphate and Mg, which may well play a critical role in SARS-CoV-2 pathogenesis. SARS-CoV-2 may induce a cytokine storm that drains ATP whose regeneration req...

Maintaining Multiple Sclerosis Care With Virtual Visits
https://www.medscape.com/viewarticle/938457

Nov 9th, 2020 - This transcript has been edited for clarity. Hi. I'm Dr Stephen Krieger from the Corinne Goldsmith Dickinson Center for Multiple Sclerosis at Mount Sinai in New York. Today I'd like to speak with you about how we have adapted to care for patients with multiple sclerosis (MS) in the era of virtual health and the unfortunately ongoing COVID-19 pandemic. A lot of attention has been paid to COVID a...

COVID-19: Is there a role for immunonutrition in obese patient?
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7647877
Journal of Translational Medicine; Di Renzo L, Gualtieri P et. al.

Nov 8th, 2020 - On December 12, 2019 a new coronavirus (SARS-CoV-2) emerged in Wuhan, China, triggering a pandemic of severe acute respiratory syndrome in humans (COVID-19). Today, the scientific community is investing all the resources available to find any therapy and prevention strategies to defeat COVID-19. In this context, immunonutrition can play a pivotal role in improving immune responses against viral...

Preventing vitamin D deficiency during the COVID-19 pandemic: UK definitions of vitamin...
https://doi.org/10.7861/clinmed.2020-0858
Clinical Medicine (London, England); Griffin G, Hewison M et. al.

Nov 7th, 2020 - There is growing evidence linking vitamin D deficiency with risk of COVID-19. It is therefore distressing that there is major disagreement about the optimal serum level for 25-hydroxyvitamin D (25(OH)D) and appropriate supplement dose. The UK Scientific Advisory Committee for Nutrition has set the lowest level for defining sufficiency (10 ng/ml or 25 nmol/L) of any national advisory body or sci...

Vitamin D Status in Hospitalized Patients with SARS-CoV-2 Infection.
https://doi.org/10.1210/clinem/dgaa733
The Journal of Clinical Endocrinology and Metabolism; Hernández JL, Nan D et. al.

Nov 7th, 2020 - The role of vitamin D status in COVID-19 patients is a matter of debate. To assess serum 25-hydroxyvitamin D (25OHD) levels in hospitalized patients with COVID-19 and to analyze the possible influence of vitamin D status on disease severity. Retrospective case-control study of 216 COVID-19 patients and 197 population-based controls. Serum 25OHD levels were measured in both groups. The associati...

The impact of SARS-CoV2 on the anxiety levels of subjects and on the anxiety and depres...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7587066
Multiple Sclerosis and Related Disorders; Dilek TD, Boybay Z et. al.

Nov 7th, 2020 - The Severe Acute Respiratory Syndrome-CoV2 outbreak was announced a pandemic by the World Health Organization on March 11th, 2020. Both the pandemic itself and the restrictions were thought to create some psychological problems especially in patients with chronic illnesses such as Multiple Sclerosis (MS). This study was conducted to evaluate the impact of SARS-CoV2 pandemic on daily lives of ch...

Does eNOS derived nitric oxide protect the young from severe COVID-19 complications?
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7609225
Ageing Research Reviews; Guan SP, Seet RCS et. al.

Nov 6th, 2020 - The COVID-19 pandemic poses an imminent threat to humanity, especially to the elderly. The molecular mechanisms underpinning the age-dependent disparity for disease progression is not clear. COVID-19 is both a respiratory and a vascular disease in severe patients. The damage endothelial system provides a good explanation for the various complications seen in COVID-19 patients. These observation...

Spotlight on COVID-19 rapid guidance: NICE's experience of producing rapid guidelines d...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7665661
Journal of Public Health (Oxford, England); Southall S, Taske N et. al.

Nov 5th, 2020 - This article highlights recent guidance from the National Institute for Health and Care Excellence (NICE). It provides an overview of the COVID-19 rapid guidance produced since March 2020, along with an account of how the organization adapted during the pandemic, developing resources to guide practice with the limited time and evidence available. The growing COVID-19 evidence base is also consi...

Vitamin D Clinical Pharmacology: Relevance to COVID-19 Pathogenesis.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7605797
Journal of the National Medical Association; Campbell PA, Young MW et. al.

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Trending Clinical Topic: Vitamin D and COVID-19
https://reference.medscape.com/viewarticle/940266

Nov 5th, 2020 - Each week, we identify one top search term, speculate about what caused its popularity, and provide an infographic on a related condition. If you have thoughts about what's trending and why, share them with us on Twitter or Facebook. Find the latest COVID-19 news and guidance in Medscape's Coronavirus Resource Center. As researchers continue to explore its possible association with COVID-19, vi...

Trending Clinical Topic: Vitamin D and COVID-19
https://reference.staging.medscape.com/viewarticle/940266

Nov 5th, 2020 - Each week, we identify one top search term, speculate about what caused its popularity, and provide an infographic on a related condition. If you have thoughts about what's trending and why, share them with us on Twitter or Facebook. Find the latest COVID-19 news and guidance in Medscape's Coronavirus Resource Center. As researchers continue to explore its possible association with COVID-19, vi...

Intake of Vitamins A, E and D Tied to Respiratory Health
https://www.medscape.com/viewarticle/940293

Nov 3rd, 2020 - NEW YORK (Reuters Health) - Higher intakes of vitamin A, E and D are associated with better respiratory health, according to new findings. Consuming more vitamin A and E in the diet and from supplements, and getting more vitamin D from supplements, was associated with a lower risk of self-reported respiratory health complaints, Dr. Suzana Almoosawi of Imperial College London and Dr. Luigi Palla...