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Prevalence and predictors of self-medication drugs to prevent or treat COVID-19: experi...
https://doi.org/10.1111/ijcp.14860
International Journal of Clinical Practice; Elayeh E, Akour A et. al.

Sep 14th, 2021 - Lack of definitive cure for COVID-19 and the late introduction of a vaccine were responsible to push the general public to look for a remedy to treat or prevent COVID-19. The objective of this study was to evaluate patterns and factors that affect self-medication practices in Jordan during the pandemic. This was a cross-sectional study using an online questionnaire that was developed, piloted a...

A Randomized Pilot Study Using Calcitriol in Hospitalized Patients.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8425676
Bone Elamir YM, Amir H et. al.

Sep 12th, 2021 - The systemic illness associated with SARS-CoV-2 infection results in hospitalization rate of 380.3 hospitalizations per 100,000 population, overwhelming health care systems. Vitamin D regulates expression of approximately 11,000 genes spanning many physiologic functions that include regulation of both innate and adaptive immune function. We investigate potential benefit of calcitriol therapy gi...

A critical update on the role of mild and serious vitamin D deficiency prevalence and t...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8321689
Nutrition (Burbank, Los Angeles County, Calif.); Bakaloudi DR, Chourdakis M

Sep 8th, 2021 - Coronavirus disease 2019 (COVID-19) has emerged as a pandemic, affecting nearly 180 million people worldwide as of June 22, 2021. Previous studies have examined the association between the mean vitamin D (Vit D) concentration of each country and COVID-19 infection and mortality rate in European countries. The aim of the present study was to critically evaluate the relationship between prevalenc...

Vitamin D levels and mortality with SARS-COV-2 infection: a retrospective two-centre co...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8423517
Postgraduate Medical Journal; Zafar M, Karkhanis M et. al.

Sep 8th, 2021 - The role of vitamin D in increased mortality with SARS-COV-2 virus, namely, COVID-19, remains uncertain. We analysed all the patients who were treated as COVID-19-positive with or without a positive swab and were tested for vitamin D levels. This was a retrospective, study involving 1226 patients swabbed for SARS-CoV-2 between the 10 February 2020 and 1 May 2020 at two hospitals of East Sussex ...

Examination of the Moderating Effect of Race on the Relationship between Vitamin D Stat...
https://doi.org/10.1080/07315724.2021.1948932
Journal of the American College of Nutrition; Crandell I, Rockwell M et. al.

Sep 3rd, 2021 - With a well-established role in inflammation and immune function, vitamin D status has emerged as a potential factor for coronavirus disease-2019 (COVID-19). The purpose of this study was to evaluate the moderating effect of race on the relationship between vitamin D status and the risk of COVID-19 test positivity, and to compare propensity score (PS) model results to those obtained from classi...

Association between Vitamin D Status and Risk of Developing Severe COVID-19 Infection: ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8425440
Journal of the American College of Nutrition; Ben-Eltriki M, Hopefl R et. al.

Sep 1st, 2021 - The relationship between 25-hydroxyvitamin D3 (25(OH)D), the surrogate marker for vitamin D3, serum concentration and COVID-19 has come to the forefront as a potential pathway to improve COVID-19 outcomes. The current evidence remains unclear on the impact of vitamin D status on the severity and outcomes of COVID-19 infection. To explore possible association between low 25(OH)D levels and risk ...

Vitamin D Status and Severe COVID-19 Disease Outcomes in Hospitalized Patients.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8404616
Journal of Primary Care & Community Health; Pecina JL, Merry SP et. al.

Aug 29th, 2021 - Vitamin D deficiency may increase the risk of severe COVID-19 disease. To determine if 25-hydroxyvitamin D [25(OH)D] levels in patients hospitalized for COVID-19 were associated with the clinical outcomes of days on oxygen, duration of hospitalization, ICU admission, need for assisted ventilation, or mortality. We conducted a retrospective study of 92 patients admitted to the hospital with SARS...

Objective Behavioral Measures in Children before, during, and after the COVID-19 Lockdo...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8394769
International Journal of Environmental Research and Publi... Shneor E, Doron R et. al.

Aug 28th, 2021 - Studies using questionnaires report that COVID-19 restrictions resulted in children spending significantly less time outdoors. This study used objective measures to assess the impact of pandemic-related restrictions on children's behavior. A total of 19 healthy 8-12-year-old boys were observed before and during social restriction periods. Of these, 11 boys were reassessed after restrictions wer...

Knowledge, Attitudes, and Practices Related to Dietary Supplementation, before and duri...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8395050
International Journal of Environmental Research and Publi... Mohsen H, Yazbeck N et. al.

Aug 28th, 2021 - At the start of 2020, a new coronavirus (COVID-19) invaded the world leading to the death of 3.92 million people. Sadly, to date, no remedy has been discovered for this virus. Preventive vaccines have been under investigation, but were unavailable until December 2020. Clinical deficiencies of nutrients may increase susceptibility to infections. This knowledge may have provided an incentive for ...

Analysis of serum cytokine and protective vitamin D levels in severe cases of COVID-19.
https://doi.org/10.1002/jmv.27294
Journal of Medical Virology; Bayraktar N, Turan H et. al.

Aug 25th, 2021 - In this study, we investigated the role and relationship between the cytokine profile and protective vitamin D by measuring their serum levels in COVID-19 intensive care unit patients with severe illnesses. A total of 74 patients were included in our study. Patients were divided into two groups. Patients in the COVID-19 group (n = 31) and individuals without a history of serious illness or infe...

Managing Immune-Related AEs in Oncology Needs Nurse Intervention
https://www.onclive.com/view/managing-immune-related-aes-in-oncology-needs-nurse-intervention

Aug 19th, 2021 - It’s imperative to stay diligent of the immune-related adverse events (AEs) that patients with cancer may experience from checkpoint inhibitors and other immunotherapy agents, especially with regards to treatment continuation and keeping hospitalizations low, according to Grace Cherry, RN, MS, NP, of the melanoma program at University of California Los Angeles. If you're an oncology nurse, y...

Evaluation of the relationship between serum levels of zinc, vitamin B12, vitamin D, an...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8426973
Journal of Medical Virology; Shakeri H, Azimian A et. al.

Aug 19th, 2021 - Due to the known anti-inflammatory and antiviral effects of zinc, 25(OH)D, and vitamin B12, in this study, we explored the association between serum levels of these micronutrients in coronavirus disease 2019 (COVID-19) patients at the time of admission and the clinical outcomes. This study was carried out on 293 patients with COVID-19, who were hospitalized at Imam Hassan hospital (Bojnourd, Ir...

Shouldn't Docs Who Spread False COVID-19 Info Lose Their Licenses?
https://www.medscape.com/viewarticle/956796

Aug 18th, 2021 - Editor's note: Find the latest COVID-19 news and guidance in Medscape's Coronavirus Resource Center. A tall, distinguished-looking physician in shirtsleeves and suspenders walked to the microphone at the Mt. Vernon, Indiana, school board meeting on a Friday evening in early August. He launched into an impassioned, 7-minute attack on the public health establishment's medical guidelines for COVID...

Influence of Vitamin D3 Levels and T Cell-Related Cytokines in Human Milk on Coronaviru...
https://doi.org/10.1089/bfm.2021.0170
Breastfeeding Medicine : the Official Journal of the Acad... Demers-Mathieu V, Lavangnananda S et. al.

Aug 14th, 2021 - Background: Vitamin D deficiency was associated with an increased risk of coronavirus disease 2019 (COVID-19) infection. Vitamin D deficient mothers are more likely to have infants with vitamin D deficiency, affecting their immunity and protection against infection. This study aimed at comparing the concentrations of vitamin D3 and T cell-related cytokines in milk between mothers with confirmed...

The association between serum levels of micronutrients and the severity of disease in p...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8223004
Nutrition (Burbank, Los Angeles County, Calif.); Beigmohammadi MT, Bitarafan S et. al.

Aug 14th, 2021 - This study aimed to compare the serum level of micronutrients with normal amounts, and assess their association with the severity of disease and inflammatory cytokines in patients with coronavirus disease 2019 (COVID-19). The present cross-sectional study included 60 patients admitted to the intensive care unit with COVID-19. We recorded data on demographic characteristics, anthropometric infor...

Prevalence of vitamin D deficiency and its prognostic impact on patients hospitalized w...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8247197
Nutrition (Burbank, Los Angeles County, Calif.); Bianconi V, Mannarino MR et. al.

Aug 14th, 2021 - Although hypovitaminosis D appears to be highly prevalent in patients with coronavirus disease 2019 (COVID-19), its impact on their prognosis remains unclear. In this study, serum 25-hydroxyvitamin D (Vit-D) level was measured in 200 patients hospitalized with COVID-19. The association between Vit-D and the composite endpoint of intensive care unit (ICU) admission/in-hospital death was explored...

Vitamin D levels associate with blood glucose and BMI in COVID-19 patients predicting d...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8385994
The Journal of Clinical Endocrinology and Metabolism; di Filippo L, Allora A et. al.

Aug 13th, 2021 - High prevalence of Vitamin-D (VD) deficiency in COVID-19 patients was reported and hypothesized to increase COVID-19 severity likely due to its negative impact on immune and inflammatory responses. Furthermore, clear associations between hypovitaminosis-D and fat body-mass excess and diabetes, factors associated with COVID-19 severity, have been widely recognized. The aim of this study was to e...

Obesity and severe coronavirus disease 2019: molecular mechanisms, paths forward, and t...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8343994
Theranostics Yan T, Xiao R et. al.

Aug 11th, 2021 - Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) appears to have higher pathogenicity among patients with obesity. Obesity, termed as body mass index greater than 30 kg/m2, has now been demonstrated to be important comorbidity for disease severity during coronavirus disease 2019 (COVID-19) pandemic and associated with adverse events. Unraveling mechanisms behind this phenomenon can ...

Vitamin D levels in children with COVID-19: a report from Turkey.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8365038
Epidemiology and Infection; Alpcan A, Tursun S et. al.

Aug 11th, 2021 - Several studies have demonstrated that higher levels of vitamin D are associated with better prognosis and outcomes in infectious diseases. We aimed to compare the vitamin D levels of paediatric patients with mild/moderate coronavirus disease 2019 (COVID-19) disease and a healthy control group. We retrospectively reviewed the medical records of patients who were hospitalised at our university h...

Association of 25-Hydroxyvitamin D Level with COVID-19-Related in-Hospital Mortality: A...
https://doi.org/10.1080/07315724.2021.1935361
Journal of the American College of Nutrition; Güven M, Gültekin H

Aug 10th, 2021 - The primary aim of this study was to compare the 25(OH)D level between patients with COVID-19 and the reference population. The secondary aim was to determine the association of 25(OH)D level with COVID-19-related in-hospital mortality. The COVID-19-positive group comprised 520 hospitalized patients and the reference population comprised 15,789 COVID-19-negative patients. The 25(OH)D level was ...