Psychoneuroendocrinology Di Nicola M, Dattoli L et. al.
Sep 21st, 2020 - The COVID-19 pandemic has given rise to stress worldwide, especially in vulnerable people like those suffering from mental illness. This study aims to investigate the psychological distress perceived by a cohort of patients with Major Depressive Disorder (MDD) or Bipolar Disorder (BD) after a seven-week period of lockdown measures, and to analyze serum 25-hydroxyvitamin D [25(OH)D] levels as a ...
Geriatric Nursing (New York, N.Y.); Simonson W
Sep 18th, 2020 - Vitamin D dosing considerations in COVID-19.|2020|Simonson W,|
PLoS Pathogens; Mohan M, Cherian JJ et. al.
Sep 18th, 2020 - Coronavirus Disease 2019 (COVID-19) pandemic remains a major public health threat in most countries. The causative severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus can lead to acute respiratory distress syndrome and result in mortality in COVID-19 patients. Vitamin D is an immunomodulator hormone with established effectiveness against various upper respiratory infections. Vita...
Current Opinion in Clinical Nutrition and Metabolic Care; Biesalski HK
Sep 17th, 2020 - Old age, obesity and vitamin D deficiency are considered as independent risk factors for severe courses of COVID-19. The aim of the review is to discuss common features of these risk factors and the impact of vitamin D. The recently discovered relationship between vitamin D and the infection pathway of the virus via the renin--angiotensin system (RAS) and the adipokines leptin and adiponectin p...
PloS One; Kaufman HW, Niles JK et. al.
Sep 17th, 2020 - Until treatment and vaccine for coronavirus disease-2019 (COVID-19) becomes widely available, other methods of reducing infection rates should be explored. This study used a retrospective, observational analysis of deidentified tests performed at a national clinical laboratory to determine if circulating 25-hydroxyvitamin D (25(OH)D) levels are associated with severe acute respiratory disease c...
Advances in Experimental Medicine and Biology; Holick MF
Sep 12th, 2020 - Vitamin D is the sunshine vitamin for good reason. During exposure to sunlight, the ultraviolet B photons enter the skin and photolyze 7-dehydrocholesterol to previtamin D3 which in turn is isomerized by the body's temperature to vitamin D3. Most humans have depended on sun for their vitamin D requirement. Skin pigment, sunscreen use, aging, time of day, season, and latitude dramatically affect...
Alternative Therapies in Health and Medicine; LaValle JB
Sep 12th, 2020 - No Abstract Available.
Drug Design, Development and Therapy; Liu G, Hong T et. al.
Sep 9th, 2020 - There is no specific and effective medication for coronavirus disease 2019 (COVID-19), and avaccine is not available in recent months. Here, we hypothesize that a single large dose of vitamin D (Vit D) could be an option for trial in COVID-19. Vit D deficiency or insufficiency is very common in the general population as well as in patients with COVID-19. It has been shown that low Vit D level i...
JAMA Network Open; Meltzer DO, Best TJ et. al.
Sep 3rd, 2020 - Vitamin D treatment has been found to decrease the incidence of viral respiratory tract infection, especially in patients with vitamin D deficiency. Whether vitamin D is associated with coronavirus disease 2019 (COVID-19) incidence is unknown. To examine whether the last vitamin D status before COVID-19 testing is associated with COVID-19 test results. This retrospective cohort study at an urba...
Aging Clinical and Experimental Research; Daneshkhah A, Agrawal V et. al.
Sep 2nd, 2020 - We present evidence for a possible role of Vitamin D (VitD) deficiency in unregulated cytokine production and inflammation leading to complications in COVID-19 patients. The time-adjusted case mortality ratio (T-CMR) was estimated as the ratio of deceased patients on day N to the confirmed cases on day N-8. The adaptive average of T-CMR (A-CMR) was calculated as a metric of COVID-19 associated ...
Advances in Respiratory Medicine; Chaabouni M, Feki W et. al.
Sep 1st, 2020 - There is increased evidence that the massive release of pro-inflammatory cytokines leading to the cytokine storm syndrome shapes the evolution of COVID-19 and is responsible of the severity of COVID-19 in some patients. A recent review argued that vitamin D deficiency could have increased the COVID-19 outbreak and suggested vitamin D supplementation as a preventive action. In fact, many factors...
Postgraduate Medical Journal; Baktash V, Hosack T et. al.
Aug 28th, 2020 - Older adults are more likely to be vitamin D deficient. The aim of the study was to determine whether these patients have worse outcomes with COVID-19. We conducted a prospective cohort study between 1 March and 30 April 2020 to assess the importance of vitamin D deficiency in older patients with COVID-19. The cohort consisted of patients aged ≥65 years presenting with symptoms consistent with ...
Reviews in Medical Virology REFERENCES; Teymoori-Rad M, Marashi SM
Aug 27th, 2020 - Evidence suggests that vitamin D supplementation could potentially be effective either in treatment or prevention of coronavirus disease 2019 (Covid-19). Indeed, several studies and trials have begun to investigate the impact of vitamin D supplementation on patients with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. In this review, we focus on the potential mechanisms ...
European Journal of Nutrition; Hastie CE, Pell JP et. al.
Aug 27th, 2020 - Low blood 25-hydroxyvitamin D (25(OH)D) concentration has been proposed as a potential causal factor in COVID-19 risk. We aimed to establish whether baseline serum 25(OH)D concentration was associated with COVID-19 mortality, and inpatient confirmed COVID-19 infection, in UK Biobank participants. UK Biobank recruited 502,624 participants aged 37-73 years between 2006 and 2010. Baseline exposure...
Journal of Translational Medicine; Xu Y, Baylink DJ et. al.
Aug 27th, 2020 - The coronavirus disease 2019 (COVID-19) pandemic has led to a declaration of a Public Health Emergency of International Concern by the World Health Organization. As of May 18, 2020, there have been more than 4.7 million cases and over 316,000 deaths worldwide. COVID-19 is caused by a highly infectious novel coronavirus known as severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), leadi...
The British Journal of Nutrition; Richardson DP, Lovegrove JA
Aug 20th, 2020 - Recent scientific evidence has indicated that the elderly have increased risk of COVID-19 infections, with over 70s and 80s being hardest hit - especially residents of care homes and in clinical settings, ethnic minorities, people who work indoors and those who are overweight and obese. Other potential risk factors include lack of exposure to sunlight, darker skin pigmentation, co-morbidities, ...
American Family Physician;
Aug 17th, 2020 - Postpartum Care, COVID-19, Augmentation Therapy, Vitamin D Supplementation.|2020||
American Journal of Therapeutics; Ohaegbulam KC, Swalih M et. al.
Aug 17th, 2020 - Coronavirus disease 2019 (COVID-19) has infected more than 4.4 million people and caused more than 300,000 deaths partly through acute respiratory distress syndrome with propensity to affect African American and Hispanic communities disproportionately. Patients with worse outcomes have exhibited higher blood plasma levels of proinflammatory cytokines. Activation of the vitamin D receptor expres...
Journal of the American College of Nutrition; Stohs SJ, Aruoma OI
Aug 16th, 2020 - Vitamin D and Wellbeing beyond Infections: COVID-19 and Future Pandemics.|2020|Stohs SJ,Aruoma OI,|
International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases; Im JH, Je YS et. al.
Aug 16th, 2020 - The relationship between immunity and nutrition is well known and its role in coronavirus disease 2019 (COVID-19) is also being paid greater attention. However, the nutritional status of COVID-19 patients is unknown. Vitamins B1, B6, B12, D (25-hydroxyvitamin D), folate, selenium, and zinc levels were measured in 50 hospitalized patients with COVID-19. A total of 76% of the patients were vitami...