×
Oxidative stress status and vitamin D levels of asymptomatic to mild symptomatic COVID-...
https://doi.org/10.1002/jmv.27606
Journal of Medical Virology; Schmitt G, Labdouni S et. al.

Jan 22nd, 2022 - It is believed that the subtle equilibrium between tolerance and immunity during the unique biological state of pregnancy, which is characterized by further physiological and hormonal changes, rends pregnant women more vulnerable to the coronavirus disease 2019 (COVID-19). In this retrospective study, confirmed COVID-19-positive pregnant women (n = 15) during their third trimester, comprising a...

Obesity and infectious diseases: pathophysiology and epidemiology of a double pandemic ...
https://doi.org/10.1038/s41366-021-01035-6 10.3390/jcm8070953 10.1126/scitranslmed.abb5280 10.3390/children4120103.
International Journal of Obesity (2005); Pugliese G, Liccardi A et. al.

Jan 22nd, 2022 - The current pandemic due to widespread SARS-CoV-19 infection has again highlighted the role of obesity, whose global prevalence increased up to 13%, as a risk factor for both susceptibility to infections and the occurrence of a more severe disease course. To date, this association has not been sufficiently explored. Obesity-related susceptibility to infectious diseases is mostly thought to be d...

Antimalarials exert a cardioprotective effect in lupus patients: Insights from the Span...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8720299
Seminars in Arthritis and Rheumatism; Rúa-Figueroa I, Rúa-Figueroa D et. al.

Jan 17th, 2022 - Factors associated with chronic heart failure (CHF) in patients with systemic lupus erythematosus (SLE) have received little attention. Recent data on the use of hydroxychloroquine in the treatment of SARS-CoV-2 infection have cast doubt on its cardiac safety. The factors associated with CHF, including therapy with antimalarials, were analyzed in a large multicenter SLE cohort. Cross-sectional ...

Effect of a single high dose of Vitamin D3 on cytokines, chemokines and growth factor i...
https://doi.org/10.1093/ajcn/nqab426
The American Journal of Clinical Nutrition; Fernandes AL, Murai IH et. al.

Jan 13th, 2022 - The modulating effect of vitamin D on cytokine levels in severe coronavirus disease 2019 (COVID-19) remains unknown. To investigate the effect of a single high-dose of vitamin D3 on cytokines, chemokines, and growth factor in hospitalized patients with moderate to severe COVID-19. This is a post-hoc, ancillary and exploratory analysis from a multicenter, double-blind, placebo-controlled, random...

The Interaction of Vitamin D and Corticosteroids: A Mortality Analysis of 26,508 Vetera...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8744830
International Journal of Environmental Research and Publi... Efird JT, Anderson EJ et. al.

Jan 12th, 2022 - This data-based cohort consisted of 26,508 (7%) United States veterans out of the 399,290 who tested positive for SARS-CoV-2 from 1 March to 10 September 2020. We aimed to assess the interaction of post-index vitamin D (Vit D) and corticosteroid (CRT) use on 30-day mortality among hospitalized and non-hospitalized patients with coronavirus disease 2019 (COVID-19). Combination Vit D and CRT drug...

Risk of Severe Coronavirus Disease 2019 Infection in Kidney Transplant Recipients.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8585609
Transplantation Proceedings; Sacristán PG, García EC et. al.

Jan 10th, 2022 - Despite all efforts, the incidence of severe coronavirus disease 2019 (COVID-19) infection has been high in renal transplant recipients, as in other groups (eg, older adults, patients with comorbidities or immunosuppression). The detection of any possible predictor of gravity could improve the early approach in these patients. We registered data from renal transplant recipients with severe acut...

Vitamin D deficiency is associated with higher risks for SARS-CoV-2 infection and COVID...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8742718
Internal and Emergency Medicine; Israel A, Cicurel A et. al.

Jan 10th, 2022 - Robust evidence of whether vitamin D deficiency is associated with COVID-19 infection and its severity is still lacking. The aim of the study was to evaluate the association between vitamin D levels and the risks of SARS-CoV-2 infection and severe disease in those infected. A retrospective study was carried out among members of Clalit Health Services (CHS), the largest healthcare organization i...

Impact of tozinameran (BNT162b2) mRNA vaccine on kidney transplant and chronic dialysis...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8731189
Journal of Nephrology; Ben-Dov IZ, Oster Y et. al.

Jan 7th, 2022 - Determining the humoral immunogenicity of tozinameran (BNT162b2) in patients requiring chronic renal replacement therapy, and its impact on COVID-19 morbidity several months after vaccination, may guide risk assessment and changes in vaccination policy. In a prospective post-vaccination cohort study with up to 5 months follow-up we studied outpatient dialysis and kidney transplant patients and ...

Association of vitamin D status with COVID-19 and its severity : Vitamin D and COVID-19...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8724612
Reviews in Endocrine & Metabolic Disorders; Bae JH, Choe HJ et. al.

Jan 5th, 2022 - Vitamin D is associated with biological activities of the innate and adaptive immune systems, as well as inflammation. In observational studies, an inverse relationship has been found between serum 25-hydroxyvitamin D (25(OH)D) concentrations and the risk or severity of coronavirus disease 2019 (COVID-19). Several mechanisms have been proposed for the role of vitamin D in COVID-19, including mo...

Association of Vitamin D Status and COVID-19-Related Hospitalization and Mortality.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8723909
Journal of General Internal Medicine; Seal KH, Bertenthal D et. al.

Jan 5th, 2022 - The relationship between vitamin D status and COVID-19-related clinical outcomes is controversial. Prior studies have been conducted in smaller, single-site, or homogeneous populations limiting adjustments for social determinants of health (race/ethnicity and poverty) common to both vitamin D deficiency and COVID-19 outcomes. To evaluate the dose-response relationship between continuous 25(OH)D...

The effect of vitamin D supplementation on mortality and intensive care unit admission ...
https://doi.org/10.1002/dmrr.3517
Diabetes/metabolism Research and Reviews; Tentolouris N, Samakidou G et. al.

Dec 30th, 2021 - The aim of this systematic review and meta-analysis was to investigate the effect of vitamin D supplementation on mortality and admission to intensive care unit (ICU) of COVID-19 patients. A systematic search of PubMed, Google Scholar, Embase, Web of Science and medRxiv with terms relative to vitamin D supplementation and COVID-19 was conducted on 26 March 2021. Comprehensive Meta-Analysis soft...

COVID-19 transmission risk factors.
https://doi.org/10.1080/20477724.2021.1993676
Pathogens and Global Health; Notari A, Torrieri G

Dec 29th, 2021 - We analyze risk factors correlated with the initial transmission growth rate of the recent COVID-19 pandemic in different countries. The number of cases follows in its early stages an almost exponential expansion; we chose as a starting point in each country the first day di with 30 cases and we fitted for 12 days, capturing thus the early exponential growth. We looked then for linear correlati...

Vitamin D: Dosing, levels, form, and route of administration: Does one approach fit all?
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8696970
Reviews in Endocrine & Metabolic Disorders; Bilezikian JP, Formenti AM et. al.

Dec 24th, 2021 - The 4th International Conference on Controversies in Vitamin D was held as a virtual meeting in September, 2020, gathering together leading international scientific and medical experts in vitamin D. Since vitamin D has a crucial role in skeletal and extra-skeletal systems, the aim of the Conference was to discuss improved management of vitamin D dosing, therapeutic levels and form or route of a...

The Role of Immunomodulatory Nutrients in Alleviating Complications Related to SARS-CoV...
https://doi.org/10.1093/advances/nmab128
Advances in Nutrition (Bethesda, Md.); Jandaghi P, Hosseini Z et. al.

Dec 22nd, 2021 - The recent coronavirus disease 2019 (COVID-19) pandemic has warranted the need to investigate potential therapies or prophylaxis against this infectious respiratory disease. There is emerging evidence about the potential role of nutrients on COVID-19 in addition to using medications such as hydroxychloroquine and azithromycin. This scoping review aims to explore the literature evaluating the ef...

Role of the T cell vitamin D receptor in severe COVID-19.
https://doi.org/10.1038/s41590-021-01098-7 10.1016/j.cegh.2021.100882 10.1001/jamainternmed.2020.3596 10.1097/QCO.0000000000000790 10.1016/j.drudis.2021.10.016 10.1038/s41590-021-01080-3 10.1016/j.immuni.2020.02.006 10.1126/science.aad1210 10.1074/jbc.M110.163790 10.1172/JCI42388 10.1056/NEJMc2000993 10.1074/jbc.M111.244061 10.1016/j.eprac.2021.09.016
Nature Immunology; Kolls JK, Garry RF

Dec 22nd, 2021 - Role of the T cell vitamin D receptor in severe COVID-19.|2021|Kolls JK,Garry RF,|metabolism,pathology,immunology,immunology,immunology,metabolism,genetics,metabolism,immunology,metabolism,immunology,immunology,metabolism,

Vitamin D Status in Hospitalized Patients with SARS-CoV-2 Infection.
https://doi.org/10.1210/clinem/dgaa733
The Journal of Clinical Endocrinology and Metabolism; Hernández JL, Nan D et. al.

Dec 22nd, 2021 - The role of vitamin D status in COVID-19 patients is a matter of debate. To assess serum 25-hydroxyvitamin D (25OHD) levels in hospitalized patients with COVID-19 and to analyze the possible influence of vitamin D status on disease severity. Retrospective case-control study of 216 COVID-19 patients and 197 population-based controls. Serum 25OHD levels were measured in both groups. The associati...

Brazilian network of COVID-19 during pregnancy (REBRACO: a multicentre study protocol).
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8685531
BMJ Open; Costa ML, Souza RT et. al.

Dec 19th, 2021 - The aim of this study was to evaluate the clinical, epidemiological and laboratory aspects of SARS-CoV-2 infection during pregnancy and postpartum in 16 maternity hospitals. A prospective multicentre study, with five axes. First, the prevalence of SARS-CoV-2 infection among women admitted for childbirth will be described in a cross-sectional study. Second, maternal and perinatal outcomes will b...

Characterizing progressive beta-cell recovery after new-onset DKA in COVID-19 provoked ...
https://doi.org/10.1016/j.jdiacomp.2021.108100
Journal of Diabetes and Its Complications; Gupta RD, Atri A et. al.

Dec 18th, 2021 - Recent literature suggests a bi-directional relationship between COVID-19 infection and diabetes mellitus, with an increasing number of previously normoglycemic adults with COVID-19 being admitted with new-onset diabetic ketoacidosis (DKA). However, the possibility of COVID-19 being a potential trigger for A-β + ketosis-prone diabetes (KPD) in these patients needs elucidation. Our study aimed a...

Effects of Vitamin D receptor gene polymorphisms on the prognosis of COVID-19.
https://doi.org/10.1111/cen.14664
Clinical Endocrinology; Apaydin T, Polat H et. al.

Dec 18th, 2021 - Vitamin D deficiency has emerged as another potential risk factor for coronavirus disease (COVID-19) due to the immunomodulatory effects of 25 hydroxyvitamin D [25 (OH)D]. Vitamin D receptor (VDR) gene polymorphisms such as Fok I, Bsm I, Apa I, and Taq I are also associated with different courses of viral infections. This study aimed to evaluate the association between the VDR gene polymorphism...

Relation of vitamin D to COVID-19.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8669943
Journal of Virological Methods; Saxena P, Nigam K et. al.

Dec 18th, 2021 - The coronavirus pandemic has lasted for more than a year now and still remains the leading cause of concern, worldwide. The causal agent; SARS- CoV-2, leads to the development of respiratory distress in the lower respiratory tract, sometimes leading to fatalities. Keeping in mind the discovery of mutant strains across the world, as well as the delay in vaccinations across vast populations, most...