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Vitamin D and covid-19.
https://doi.org/10.1136/bmj.n544
BMJ (Clinical Research Ed.); Vimaleswaran KS, Forouhi NG et. al.

Mar 5th, 2021 - Vitamin D and covid-19.|2021|Vimaleswaran KS,Forouhi NG,Khunti K,|

Vitamin D deficiency, secondary hyperparathyroidism and respiratory insufficiency in ho...
https://doi.org/10.1007/s40618-021-01535-2 10.1056/NEJMoa2002032 10.1007/s11154-017-9424-1 10.1007/s00198-003-1390-7 10.1017/S0007114599000264 10.1001/jama.2020.5394 10.18632/aging.103980 10.1001/jamanetworkopen.2020.19722 10.1530/eje-20-0665 10.1371/journal.pone.0011088 10.1136/bmj.i6583 10.1111/joim.13158 10.1093/jn/nxaa332 10.1093/ajcp/aqaa252 10.1210/clinem/dgaa733 10.1016/j.jiph.2020.05.029 10.1007/s12020-020-02383-5 10.18632/aging.103526 10.1056/nejm200005043421806 10.1210/jc.2011-0385 10.1210/jc.2011-2218 10.1016/j.thromres.2020.04.024 10.1056/NEJMoa2020283 10.1530/eje-20-0335 10.2337/dc20-1340 10.1016/j.clnu.2019.12.028 10.1007/s40520-020-01650-9 10.1089/ars.2017.7462 10.1038/s41598-017-03474-6 10.1016/j.pharmthera.2010.06.003 10.1097/MCO.0b013e32834f0027 10.1016/j.jsbmb.2020.105751 10.1136/postgradmedj-2020-139065 10.1007/s12020-020-02530-y 10.1172/jci132767 10.1016/j.mehy.2004.03.041 10.1007/s40618-020-01237-1 10.1210/jc.2018-02216
Journal of Endocrinological Investigation; Mazziotti G, Lavezzi E et. al.

Mar 5th, 2021 - Hypovitaminosis D has emerged as potential risk factor for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in the general population with variable effects on the outcome of the coronavirus disease-19 (COVID-19). The aim of this retrospective single-center study was to investigate the impact of hypovitaminosis D and secondary hyperparathyroidism on respiratory outcomes of ...

Circulating Vitamin D levels status and clinical prognostic indices in COVID-19 patients.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7928197
Respiratory Research; Ricci A, Pagliuca A et. al.

Mar 4th, 2021 - Several immune mechanisms activate in COVID-19 pathogenesis. Usually, coronavirus infection is characterized by dysregulated host immune responses, interleukine-6 increase, hyper-activation of cytotoxic CD8 T lymphocytes. Interestingly, Vitamin D deficiency has been often associated with altered immune responses and infections. In the present study, we evaluated Vitamin D plasma levels in patie...

Oral high dose vitamin D for the treatment of diabetic patients with COVID-19: A protoc...
https://doi.org/10.1097/MD.0000000000024517
Medicine Nie X, Chen J et. al.

Mar 3rd, 2021 - Type 2 diabetes mellitus patients complicated with infections experience severe vitamin D deficiency. High-dose vitamin D is applied to the treatment of corona virus disease 2019 (COVID-19) by some researchers, and good results have been achieved. However, the efficacy of vitamin D in the treatment of infections in COVID-19 patients with diabetes remains unclarified. This study aims to explore ...

Obesity in COVID-19 era, implications for mechanisms, comorbidities, and prognosis: a r...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7909378
International Journal of Obesity (2005); Aghili SMM, Ebrahimpur M et. al.

Feb 27th, 2021 - Recent studies have shown that obesity is associated with the severity of coronavirus disease (COVID-19). We reviewed clinical studies to clarify the obesity relationship with COVID-19 severity, comorbidities, and discussing possible mechanisms. The electronic databases, including Web of Science, PubMed, Scopus, and Google Scholar, were searched and all studies conducted on COVID-19 and obesity...

Increased COVID-19 infections in women with polycystic ovary syndrome: a population-bas...
https://doi.org/10.1530/EJE-20-1163
European Journal of Endocrinology; Subramanian A, Anand A et. al.

Feb 26th, 2021 - Several recent observational studies have linked metabolic co-morbidities to an increased risk from COVID-19. Here we investigated whether women with PCOS are at an increased risk of COVID-19 infection. Population-based closed cohort study between 31st January 2020 and 22nd July 2020 in the setting of a UK primary care database (The Health Improvement Network, THIN). Main outcome was incidence ...

Foreword - The importance of a healthy microbiota in the era of COVID-19.
https://doi.org/10.3920/BM2021.x001
Beneficial Microbes; Venema K

Feb 25th, 2021 - At the start of 2020 we were thrilled to have reached 10 years of Beneficial Microbes! Little did we know that soon after Europe and the rest of the world (with Asia already earlier) would be in lock-down due to COVID-19. It has been a strange year. And now, at the start of 2021, the excitement of having a vaccine is tempered by the fact that everywhere mutants of the virus pop up. Although thi...

Scientists Say 'Health Warning' Needed on Vit D/COVID-19 Preprint
https://www.medscape.com/viewarticle/946314

Feb 22nd, 2021 - A preprint study, showing that vitamin D (calcifediol, [25(OH)D3]) given to patients hospitalized with COVID-19 reduces mortality by 60%, has been met with a raft of criticism from experts who urge caution when interpreting the results. Despite being published as a preprint on January 22, The Lancet has now rejected the paper in its current form, and the authors, led by Natalia García Giralt, P...

An Evaluation of Serum 25-Hydroxy Vitamin D Levels in Patients with COVID-19 in New Yor...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7898298
Journal of the American College of Nutrition; Gavioli EM, Miyashita H et. al.

Feb 19th, 2021 - Deterioration of patients from COVID-19 is associated with cytokine release syndrome attributed to an elevation in pro-inflammatory cytokines. Vitamin D reduces proinflammatory cytokines, and has the possibility of reducing complications from respiratory tract illnesses. This was a retrospective, observational, cohort study of patients with COVID-19 disease within a New York City Health System....

Low Vitamin D Status at Admission as a Risk Factor for Poor Survival in Hospitalized Pa...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7899172
Journal of the American College of Nutrition; Infante M, Buoso A et. al.

Feb 18th, 2021 - Preliminary findings suggest a relationship between lower serum 25-hydroxyvitamin D [25(OH)D] levels and incidence and severity of COVID-19. The aim of this study was to evaluate the relationship between vitamin D status at admission and different markers of inflammation, coagulation, and sepsis in hospitalized patients with COVID-19. We conducted a retrospective study on 137 consecutive patien...

Risk Mortality, prevalence, and possible therapeutics to treat diabetic patients infect...
https://doi.org/10.2174/1573399817666210216085105
Current Diabetes Reviews; Ashique S, Sandhu NK

Feb 17th, 2021 - The whole world is facing the current potential life-threatening virus nCOVID-19, the most severe health crisis in the modern era. The World Health Organization (WHO) has announced the nCOVID-19 as a pandemic in global concern. People with diabetes are not more likely to get nCOVID-19 than the general population. However, nCOVID-19 can cause more severe symptoms and complications in some people...

Perspective: Vitamin D supplementation prevents rickets and acute respiratory infection...
https://doi.org/10.7861/clinmed.2021-0035
Clinical Medicine (London, England); Griffin G, Hewison M et. al.

Feb 17th, 2021 - The value of vitamin D supplementation in the treatment or prevention of various conditions is often viewed with scepticism as a result of contradictory results of randomised trials. It is now becoming apparent that there is a pattern to these inconsistencies. A recent large trial has shown that high-dose intermittent bolus vitamin D therapy is ineffective at preventing rickets - the condition ...

l-Cysteine Stimulates the Effect of Vitamin D on Inhibition of Oxidative Stress, IL-8, ...
https://doi.org/10.1080/07315724.2020.1850371
Journal of the American College of Nutrition; Jain SK, Micinski D et. al.

Feb 17th, 2021 - Objective: Vitamin D deficiency is common in the general population and diabetic patients, and supplementation with vitamin D is widely used to help lower oxidative stress and inflammation. The cytokine storm in SARS-CoV2 infection has been linked with both diabetes and Vitamin D deficiency. This study examined the hypothesis that supplementation with vitamin D, in combination with l-cysteine (...

Potential Efficacy of Nutrient Supplements for Treatment or Prevention of COVID-19.
https://doi.org/10.1080/19390211.2021.1881686
Journal of Dietary Supplements; Bogan-Brown K, Nkrumah-Elie Y et. al.

Feb 17th, 2021 - COVID-19 (COronaVIrus Disease of 2019), the disease caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), represents an ongoing global health challenge and the deadliest epidemic coronavirus outbreak to date. Early sequencing of the viral genome and knowledge from past coronavirus outbreaks (SARS-CoV-1 and Middle East Respiratory Syndrome, MERS) has led to rapid advances i...

Do Zinc and Vitamin C Reduce COVID Symptoms?
https://www.medscape.com/viewarticle/945794

Feb 16th, 2021 - Find the latest COVID-19 news and guidance in Medscape's Coronavirus Resource Center. This transcript has been edited for clarity. Welcome to Impact Factor, your weekly dose of commentary on a new medical study. I'm Dr F. Perry Wilson of the Yale School of Medicine. Wouldn't it be nice if there was a treatment for COVID-19 that was safe, effective, cheap, and out of the control of faceless phar...

Vitamin D supplementation protects against reductions in plasma 25-hydroxyvitamin D ind...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7881347
Physiological Reports; Barker T, May HT et. al.

Feb 13th, 2021 - Low vitamin D (serum or plasma 25-hydroxyvitamin D (25(OH)D)) is a global pandemic and associates with a greater prevalence in all-cause and cardiovascular mortality and morbidity. Open-heart surgery is a form of acute stress that decreases circulating 25(OH)D concentrations and exacerbates the preponderance of low vitamin D in a patient population already characterized by low levels. Although ...

Determination of interest in vitamin use during COVID-19 pandemic using Google Trends d...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7797169
Nutrition (Burbank, Los Angeles County, Calif.); Çimke S, Yıldırım Gürkan D

Feb 12th, 2021 - The aim of this study was to determine the interest in vitamin use during the COVID-19 pandemic usıng Google Trends data. Searches were made between January 1, 2016 and August 30, 2020. First, the word "vitamin" was searched. Additionally, the search words "vitamin," "COVID-19," "immunity," and Vitamin D," "Vitamin C," "Vitamin E," and "Vitamin A" were searched comparatively. Search was made in...

Dietary Intake and Mental Health among Saudi Adults during COVID-19 Lockdown.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7916162
International Journal of Environmental Research and Publi... Alfawaz H, Yakout SM et. al.

Feb 12th, 2021 - The study aimed to explore the influence of the COVID-19 lockdown on the mental status and dietary intake of residents in Saudi Arabia. In this cross-sectional study, an online survey was conducted from 11 May to 6 June 2020 corresponding to almost two weeks during and after Ramadan (23 April-23 May 2020). The Patient Health Questionnaire was used to assess anxiety, depression, and insomnia. Lo...

The comprehensive clinic, laboratory, and instrumental evaluation of children with COVI...
https://doi.org/10.1002/jmv.26871
Journal of Medical Virology; Isoldi S, Mallardo S et. al.

Feb 11th, 2021 - To perform a comprehensive clinic, laboratory, and instrumental evaluation of children affected by coronavirus disease (COVID-19). Children with a positive result of nasopharyngeal swab for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) underwent laboratory tests, anal and conjunctival swab, electrocardiography, lung, abdomen, and cardiac ultrasound. Twenty-four-hour ambulatory bl...

The impact of outdoor air pollution on COVID-19: a review of evidence from in vitro, an...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7879496
European Respiratory Review : an Official Journal of the ... Bourdrel T, Annesi-Maesano I et. al.

Feb 11th, 2021 - Studies have pointed out that air pollution may be a contributing factor to the coronavirus disease 2019 (COVID-19) pandemic. However, the specific links between air pollution and severe acute respiratory syndrome-coronavirus-2 infection remain unclear. Here we provide evidence from in vitro, animal and human studies from the existing literature. Epidemiological investigations have related vari...