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Coronavirus (COVID-19) Update: Daily Roundup August 6, 2020 | FDA
https://www.fda.gov/news-events/press-announcements/coronavirus-covid-19-update-daily-roundup-august-6-2020

Aug 6th, 2020 - For Immediate Release: August 06, 2020 The U.S. Food and Drug Administration today announced the following actions taken in its ongoing response effort to the COVID-19 pandemic: On August 4, the FDA issued Emergency Use Authorizations (EUAs) for ventilator-related devices to: Lombardi Undersea, for its Subsalve Oxygen Treatment Hood, which is a patient interface intended for helmet-based Non-In...

The efficacy and safety of Chinese traditional medicine injections on patients with cor...
https://doi.org/10.1097/MD.0000000000021024
Medicine Li Y, Xu H et. al.

Aug 5th, 2020 - The pandemic caused by the coronavirus disease 2019 (COVID-19) infection has exposed vulnerable populations to an unprecedented global health crisis. Research reported that Chinese traditional medicine injections were used in patients with COVID-19 infection and showed significant effects, and there have been no systematic review and meta-analyses to investigate the effects and safety of Chines...

Anosmia in the course of COVID-19: A case report.
https://doi.org/10.1097/MD.0000000000021280
Medicine Pissurno NSCA, Lichs GGC et. al.

Aug 5th, 2020 - A sudden onset of anosmia has been recently recognized as a symptom of coronavirus disease (COVID-19). Here, we describe a case of complete anosmia in a young male with COVID-19. Although he had fever and odynophagia, no abnormalities were observed in his nasopharyngeal mucosa, suggesting that his anosmia resulted from olfactory neuropathy. COVID-19 was confirmed by RNA detection in nasopharyng...

Traditional Chinese medicine for the treatment of pulmonary fibrosis: A protocol for sy...
https://doi.org/10.1097/MD.0000000000021310
Medicine Li LJ, Chen X et. al.

Aug 5th, 2020 - Since December 2019, there have been many cases of viral pneumonia of unknown causes in Wuhan City, Hubei Province. During the period of novel coronavirus, according to the observation of limited autopsy and biopsy pathological results, pulmonary interstitial fibrosis appeared in some pathological changes of lung. Idiopathic pulmonary fibrosis (IPF) is a chronic progressive interstitial pneumon...

The safety and effectiveness of rehabilitation exercises on COVID-19 patients: A protoc...
https://doi.org/10.1097/MD.0000000000021373
Medicine Gu R, Xu S et. al.

Aug 5th, 2020 - Corona Virus Disease 2019 (COVID-19) is spreading fast starting late 2019. It mainly affects the human respiratory system. Many reports revealed that rehabilitation exercise can improve respiratory function and relieve the pressure from diseases, but there is no evidence to prove its effects on COVID-19. This protocol of systematic review and meta-analysis will clarify the safety and effectiven...

The Control and Prevention of COVID-19 Transmission in Children: A Protocol for Systema...
https://doi.org/10.1097/MD.0000000000021393
Medicine Medeiros GCBS, Nunes ACF et. al.

Aug 5th, 2020 - The pandemic following the rapid spread of the new SARS-CoV-2 virus has hit all continents and caused thousands of deaths worldwide. Evidence has been published on epidemiological and clinical characteristics of population groups considered at risk; however, information for the other population groups, especially for the child population, is needed. In this context, this protocol describes a sy...

How Is Morocco Reacting to COVID-19 Crisis in Anticancer Centers?
https://doi.org/10.1177/1073274820941973
Cancer Control : Journal of the Moffitt Cancer Center; Oualla K, Nouiakh L et. al.

Aug 5th, 2020 - The world is facing the pandemic linked to COVID-19 virus infection that has rapidly spread worldwide, and severe complications have been reported to occur in around a third of patients. To date, there is no approved vaccine or specific therapy against COVID-19, but many trials are ongoing with some of them showing promising results. It has been shown recently that patients with cancer are at h...

Peripheral Blood Examination Findings in SARS-CoV-2 Infection.
https://doi.org/10.1093/ajcp/aqaa108
American Journal of Clinical Pathology; Nazarullah A, Liang C et. al.

Aug 5th, 2020 - Peripheral blood abnormalities in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have not been fully elucidated. We report qualitative and quantitative peripheral blood findings in coronavirus disease 2019 (COVID-19) patients and compare them with a control group. We reviewed electronic medical records, complete blood counts, peripheral blood smears, and flow cytometry data in 12 ...

Exacerbating Inequalities: Social Networks, Racial/Ethnic Disparities, and the COVID-19...
https://doi.org/10.1093/geronb/gbaa117
The Journals of Gerontology. Series B, Psychological Sciences and Social Sciences; Gauthier GR, Smith JA et. al.

Aug 5th, 2020 - The disruption and contraction of older adults' social networks are among the less-discussed consequences of the COVID-19 pandemic. Our objective is to provide an evidence-based commentary on racial/ethnic disparities in social network resources and draw attention to the ways in which disasters differentially impact social networks, with meaningful insight for the ongoing pandemic. We draw upon...

Audio Interview: The Impact of Covid-19 on Patients with Other Diseases, with Arnold Ep...
https://doi.org/10.1056/NEJMe2027046
The New England Journal of Medicine; Rubin EJ, Baden LR et. al.

Aug 5th, 2020 - Audio Interview: The Impact of Covid-19 on Patients with Other Diseases, with Arnold Epstein.|2020|Rubin EJ,Baden LR,Epstein A,Morrissey S,|

Prognosis of COVID-19 in patients with breast cancer: A protocol for systematic review ...
https://doi.org/10.1097/MD.0000000000021487
Medicine Sheng Z, Zhang L et. al.

Aug 5th, 2020 - Coronavirus disease 2019 (COVID-19) has become a pandemic in the world and posed a great threat to people's health. Several meta-analyses have indicated that many comorbidities were associated with increased risk of COVID-19 severity or mortality. The original report also showed that the mortality rate of COVID-19 in breast cancer patients is more dependent on comorbidities than previous radiat...

SARS-CoV-2 infection associated with micturition syncope: Our experience with 4 case re...
https://doi.org/10.1097/MD.0000000000021512
Medicine Birlutiu V, Birlutiu RM et. al.

Aug 5th, 2020 - Syncope is described as the loss of consciousness and postural muscle tone with a short duration and fast onset. Micturition syncope can be caused by abnormal vasovagal response or by the dysfunction of the blood pressure regulating mechanism, which occurs before, during, or immediately after urination. We present 4 cases of COVID-19 hospitalized in the Department of Infectious Diseases of the ...

D-dimer surge and coagulation disorders in COVID-19 related pneumonia patients with car...
https://doi.org/10.1097/MD.0000000000021513
Medicine Wang X, Du B et. al.

Aug 5th, 2020 - Cardiac injury and coagulation disorders have been two increasing concerns in the management of patients with severe coronavirus disease (COVID-19). Coagulation disorders in COVID-19 patients with cardiac injury have not been characterized. We analyzed the data of five COVID-19 patients with cardiac injury who had D-dimer surge (defined as a rapid increase in the D-dimer level in 72 h, from <5-...

Therapeutic response to corticosteroids in a critically ill patient with COVID-19: A ca...
https://doi.org/10.1097/MD.0000000000021597
Medicine Wang K, Tan F et. al.

Aug 5th, 2020 - Since the coronavirus disease 2019 (COVID-19) outbreak in Wuhan in late 2019, controversy on the use of corticosteroids for COVID-19 has obtained increasing attention. We present 1 critically ill patient who had a rapid therapeutic response to moderate-dose corticosteroids. A 53-year-old critically ill woman from Wuhan suffered with COVID-19. The chest computed tomography scan was suggestive of...

Clinical remission of a critically ill COVID-19 patient treated by human umbilical cord...
https://doi.org/10.1097/MD.0000000000021429
Medicine Liang B, Chen J et. al.

Aug 5th, 2020 - The COVID-19 cases increased very fast in January and February 2020. The mortality among critically ill patients, especially the elder ones, is relatively high. Considering many patients died of severe inflammation response, it is urgent to develop effective therapeutic strategies for these patients. The human umbilical cord mesenchymal stem cells (hUCMSCs) have shown good capabilities to modul...

Spectrum of podocytopathies in new-onset nephrotic syndrome following COVID-19 disease:...
https://doi.org/10.1186/s12882-020-01970-y
BMC Nephrology; Gupta RK, Bhargava R et. al.

Aug 5th, 2020 - Coronavirus disease-2019 (COVID-19) is an ongoing pandemic which has affected over 12 million people across the globe. Manifestations in different organs systems are being reported regularly. Renal biopsy findings in hospitalized COVID-19 patients presenting solely with acute kidney injury (AKI) have recently been described in published literature in few case reports. The findings include diffu...

Innovation Lessons From the COVID-19 Pandemic.
https://doi.org/10.1016/j.mayocp.2020.05.024
Mayo Clinic Proceedings; Farrugia G, Plutowski RW

Aug 5th, 2020 - Innovation Lessons From the COVID-19 Pandemic.|2020|Farrugia G,Plutowski RW,|

Clinical Trial End Points in Severe COVID-19.
https://doi.org/10.1016/j.mayocp.2020.05.025
Mayo Clinic Proceedings; Desai A, Kulkarni A et. al.

Aug 5th, 2020 - Clinical Trial End Points in Severe COVID-19.|2020|Desai A,Kulkarni A,Rajkumar SV,Gyawali B,|

Cardiovascular Health in the COVID-19 Era: A Call for Action and Education.
https://doi.org/10.1016/j.mayocp.2020.05.031
Mayo Clinic Proceedings; Vallabhajosyula S, Friedman PA et. al.

Aug 5th, 2020 - Cardiovascular Health in the COVID-19 Era: A Call for Action and Education.|2020|Vallabhajosyula S,Friedman PA,Bell MR,|

Sex Differences in Case Fatality Rate of COVID-19: Insights From a Multinational Registry.
https://doi.org/10.1016/j.mayocp.2020.05.014
Mayo Clinic Proceedings; Alkhouli M, Nanjundappa A et. al.

Aug 5th, 2020 - To confirm whether a relationship exists between male sex and coronavirus disease 2019 (COVID-19) mortality and whether this relationship is age dependent. We queried the COVID-19 Research Network, a multinational database using the TriNetX network, to identify patients with confirmed COVID-19 infection. The main end point of the study was all-cause mortality. A total of 14,712 patients were in...

Smell and Taste Dysfunction in Patients With COVID-19: A Systematic Review and Meta-ana...
https://doi.org/10.1016/j.mayocp.2020.05.030
Mayo Clinic Proceedings; Agyeman AA, Chin KL et. al.

Aug 5th, 2020 - To estimate the prevalence of olfactory and gustatory dysfunctions (OGDs) among patients infected with novel coronavirus disease 2019 (COVID-19). A systematic review was conducted by searching MEDLINE, EMBASE, and the preprint server MedRxiv from their inception until May 11, 2020, using the terms anosmia or hyposmia or dysosmia or olfactory dysfunction or olfaction disorder or smell dysfunctio...

Prevalence and Mortality of COVID-19 Patients With Gastrointestinal Symptoms: A Systema...
https://doi.org/10.1016/j.mayocp.2020.06.003
Mayo Clinic Proceedings; Tariq R, Saha S et. al.

Aug 5th, 2020 - To perform a systematic review and meta-analysis evaluating the prevalence of gastrointestinal (GI) symptoms and mortality in patients with coronavirus disease 2019 (COVID-19) diagnosed. A systematic search of MEDLINE, EMBASE, Cochrane Central Register of Controlled Trials, Cochrane Database of Systematic Reviews, and Scopus was performed from December 1, 2019 to May 7, 2020. Observational stud...

Acute QT Interval Modifications During Hydroxychloroquine-Azithromycin Treatment in the...
https://doi.org/10.1016/j.mayocp.2020.05.005
Mayo Clinic Proceedings; Voisin O, Lorc'h EL et. al.

Aug 5th, 2020 - Among candidate drugs to treat coronavirus disease 2019 (COVID-19), the combination of hydroxychloroquine (HCQ) and azithromycin (AZ) has received intense worldwide attention. Even as the efficacy of this combination is under evaluation, clinicians have begun to use it largely. As these medications are known to prolong the QT interval, we analyzed serial electrocardiograms recorded in patients ...

Seasonality of Coronavirus 229E, HKU1, NL63, and OC43 From 2014 to 2020.
https://doi.org/10.1016/j.mayocp.2020.05.032
Mayo Clinic Proceedings; Rucinski SL, Binnicker MJ et. al.

Aug 5th, 2020 - The possibility of seasonality of COVID-19 is being discussed; we show clinical microbiology laboratory data illustrating seasonality of coronaviruses 229E, HKU1, NL63, and OC43. The data shown are specific to the 4 studied coronaviruses and may or may not generalize to COVID-19.

Telestroke in the Time of COVID-19: The Mayo Clinic Experience.
https://doi.org/10.1016/j.mayocp.2020.06.007
Mayo Clinic Proceedings; Huang JF, Greenway MRF et. al.

Aug 5th, 2020 - On March 11, 2020, the World Health Organization declared the coronavirus disease 2019 (COVID-19) a pandemic, and in the weeks following, public health organizations, medical associations, and governing bodies throughout the world recommended limiting contact with others to "flatten the curve" of COVID-19. Although both ischemic and hemorrhagic strokes have been reported with COVID-19, there ha...

Sex Hormones and Novel Corona Virus Infectious Disease (COVID-19).
https://doi.org/10.1016/j.mayocp.2020.05.013
Mayo Clinic Proceedings; Al-Lami RA, Urban RJ et. al.

Aug 5th, 2020 - Given the rapid spread of the coronavirus disease 2019 (COVID-19) pandemic and its overwhelming effect on health care systems and the global economy, innovative therapeutic strategies are urgently needed. The proposed primary culprit of COVID-19 is the intense inflammatory response-an augmented immune response and cytokine storm-severely damaging the lung tissue and rendering some patients' con...

SARS-CoV-2 Infection and COVID-19 During Pregnancy: A Multidisciplinary Review.
https://doi.org/10.1016/j.mayocp.2020.05.011
Mayo Clinic Proceedings; Narang K, Enninga EAL et. al.

Aug 5th, 2020 - The global pandemic of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the cause of coronavirus disease 2019 (COVID-19), has been associated with worse outcomes in several patient populations, including the elderly and those with chronic comorbidities. Data from previous pandemics and seasonal influenza suggest that pregnant women may be at increased risk for infection-associated ...

Covid-19: NHS Test and Trace must improve for schools to reopen safely, say researchers.
https://doi.org/10.1136/bmj.m3083
BMJ (Clinical Research Ed.); Wise J

Aug 5th, 2020 - Covid-19: NHS Test and Trace must improve for schools to reopen safely, say researchers.|2020|Wise J,|

Covid-19: UK hospitals to get rapid tests from September.
https://doi.org/10.1136/bmj.m3087
BMJ (Clinical Research Ed.); Mahase E

Aug 5th, 2020 - Covid-19: UK hospitals to get rapid tests from September.|2020|Mahase E,|

Reprocessing filtering facepiece respirators in primary care using medical autoclave: p...
https://doi.org/10.1136/bmjopen-2020-039454
BMJ Open; Harskamp RE, van Straten B et. al.

Aug 5th, 2020 - There are widespread shortages of personal protective equipment as a result of the COVID-19 pandemic. Reprocessing filtering facepiece particle (FFP)-type respirators may provide an alternative solution in keeping healthcare professionals safe. Prospective, bench-to-bedside. A primary care-based study using FFP-2 respirators without exhalation valve (3M Aura 1862+ (20 samples), Maco Pharma ZZM0...

Plasmapheresis, Anti-ACE2 and Anti-FcγRII Monoclonal Antibodies: A Possible Treatment f...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7351975
Drug Design, Development and Therapy; Sedokani A, Feizollahzadeh S

Aug 5th, 2020 - In March 2020, the WHO declared the COVID-19 disease as a pandemic disease. There have been studies on the COVID-19 to find a certain treatment, but yet, there is no certain cure. In this article, we present a possible way to treat severe cases of COVID-19. Based on the previous studies, there are similarities between the spike antigens of SARS-CoV and SARS-CoV-2 viruses. It is expected that th...

Covid-19 Infection in Older Adults: A Geriatrician's Perspective.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7351627
Clinical Interventions in Aging; Isik AT

Aug 5th, 2020 - The pandemic of the Covid-19 virus has become the main issue all over the world. In its current form, the disease is more severe in geriatric cases and individuals with chronic disease, even causing death. In older adults and atypical presentations, testing strategies for Covid-19, potential drug interactions of experimental Covid-19 therapies, and ageism are important issues in the course of t...

Retraction of: No Deleterious Effect of Lockdown Due to COVID-19 Pandemic on Glycaemic ...
https://doi.org/10.1089/dia.2020.0184.retract
Diabetes Technology & Therapeutics;

Aug 5th, 2020 - Retraction of: No Deleterious Effect of Lockdown Due to COVID-19 Pandemic on Glycaemic Control, Measured by Glucose Monitoring, in Adults with Type 1 Diabetes. Beato-Vibora PI. Diabetes Technol Ther 2020; epub DOI: 10.1089/dia.2020.0184.|2020||

Coronavirus (COVID-19) Update: Daily Roundup August 5, 2020 | FDA
https://www.fda.gov/news-events/press-announcements/coronavirus-covid-19-update-daily-roundup-august-5-2020

Aug 5th, 2020 - For Immediate Release: August 05, 2020 The U.S. Food and Drug Administration today announced the following actions taken in its ongoing response effort to the COVID-19 pandemic: The FDA issued its first warning letter to New Life International and its second warning letter to Fishman Chemical of North Carolina, LLC, both of which distribute chloroquine phosphate products intended to treat disea...

COVID-19: Education and Licensure Disruption.
https://www.ncbi.nlm.nih.gov/pubmed/32753518
Journal of Dental Hygiene : JDH; Stolberg RL

Aug 4th, 2020 - COVID-19: Education and Licensure Disruption.|2020|Stolberg RL,|

Two decades of pandemic war games failed to account for Donald Trump.
https://doi.org/10.1038/d41586-020-02277-6
Nature Maxmen A, Tollefson J

Aug 4th, 2020 - Two decades of pandemic war games failed to account for Donald Trump.|2020|Maxmen A,Tollefson J,|

Pneumomediastinum in COVID-19 patients: a case series of a rare complication.
https://doi.org/10.1093/ejcts/ezaa222
European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery; Volpi S, Ali JM et. al.

Aug 4th, 2020 - Pneumomediastinum is a rare clinical finding, but one which can be the source of significant concern for clinicians. By presenting 3 such cases, we highlight that pneumomediastinum can complicate the course of a severe coronavirus disease 2019 infection but emphasize that conservative management is the first-line method of treatment, with gradual resorption of the air from the tissues. It is im...

Long term respiratory complications of covid-19.
https://doi.org/10.1136/bmj.m3001
BMJ (Clinical Research Ed.); Fraser E

Aug 4th, 2020 - Long term respiratory complications of covid-19.|2020|Fraser E,|

Covid-19: US needs a national plan to fight rising infections, experts say.
https://doi.org/10.1136/bmj.m3072
BMJ (Clinical Research Ed.); Tanne JH

Aug 4th, 2020 - Covid-19: US needs a national plan to fight rising infections, experts say.|2020|Tanne JH,|

Covid-19: Should the UK be aiming for elimination?
https://doi.org/10.1136/bmj.m3071
BMJ (Clinical Research Ed.); Torjesen I

Aug 4th, 2020 - Covid-19: Should the UK be aiming for elimination?|2020|Torjesen I,|

Inequities During COVID-19.
https://doi.org/10.1542/peds.2020-1501
Pediatrics Ambrose AJH

Aug 4th, 2020 - Inequities During COVID-19.|2020|Ambrose AJH,|

Telemedicine and Health Disparities During COVID-19.
https://doi.org/10.1542/peds.2020-1586
Pediatrics Katzow MW, Steinway C et. al.

Aug 4th, 2020 - Telemedicine and Health Disparities During COVID-19.|2020|Katzow MW,Steinway C,Jan S,|

Evidence-Based Considerations Exploring Relations between SARS-CoV-2 Pandemic and Air P...
https://doi.org/10.3390/ijerph17155573
International Journal of Environmental Research and Public Health; Borro M, Di Girolamo P et. al.

Aug 4th, 2020 - The COVID-19/SARS-CoV-2 pandemic struck health, social and economic systems worldwide, and represents an open challenge for scientists -coping with the high inter-individual variability of COVID-19, and for policy makers -coping with the responsibility to understand environmental factors affecting its severity across different geographical areas. Air pollution has been warned of as a modifiable...

Measurement Method for Evaluating the Lockdown Policies during the COVID-19 Pandemic.
https://doi.org/10.3390/ijerph17155574
International Journal of Environmental Research and Public Health; Al Zobbi M, Alsinglawi B et. al.

Aug 4th, 2020 - Coronavirus Disease 2019 (COVID-19) has affected day to day life and slowed down the global economy. Most countries are enforcing strict quarantine to control the havoc of this highly contagious disease. Since the outbreak of COVID-19, many data analyses have been done to provide close support to decision-makers. We propose a method comprising data analytics and machine learning classification ...

Bidirectional Influence of the COVID-19 Pandemic Lockdowns on Health Behaviors and Qual...
https://doi.org/10.3390/ijerph17155575
International Journal of Environmental Research and Public Health; Wang X, Lei SM et. al.

Aug 4th, 2020 - The coronavirus disease 2019 (COVID-19) pandemic has created challenges that have caused profound changes in health behaviors. This study aimed to explore how COVID-19 is affecting the health-related quality of life (QoL) among Chinese adults. The data of health-related behaviors and QoL were collected via online surveys from 2289 adults (mean age = 27.8 ± 12 years) who had been isolated at hom...

Endothelial dysfunction in COVID-19: a position paper of the ESC Working Group for Athe...
https://doi.org/10.1093/cvr/cvaa230
Cardiovascular Research; Evans PC, Ed Rainger G et. al.

Aug 4th, 2020 - The COVID-19 pandemic is an unprecedented healthcare emergency causing mortality and illness across the world. Although primarily affecting the lungs, the SARS-CoV-2 virus also affects the cardiovascular system. In addition to cardiac effects, e.g. myocarditis, arrhythmias, and myocardial damage, the vasculature is affected in COVID-19, both directly by the SARS-CoV-2 virus, and indirectly as a...

Relationship between the ABO Blood Group and the COVID-19 Susceptibility.
https://doi.org/10.1093/cid/ciaa1150
Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America; Zhao J, Yang Y et. al.

Aug 4th, 2020 - To explore any relationship between the ABO blood group and the COVID-19 susceptibility, we compared ABO blood group distributions in 2,173 COVID-19 patients with local control populations, and found that blood group A was associated with an increased risk of infection, whereas group O was associated with a decreased risk.

Estimation Without Representation: Early Severe Acute Respiratory Syndrome Coronavirus ...
https://doi.org/10.1093/infdis/jiaa429
The Journal of Infectious Diseases; Shook-Sa BE, Boyce RM et. al.

Aug 4th, 2020 - The recent development and regulatory approval of a variety of serological assays indicating the presence of antibodies against severe acute respiratory syndrome coronavirus 2 has led to rapid and widespread implementation of seroprevalence studies. Accurate estimates of seroprevalence are needed to model transmission dynamics and estimate mortality rates. Furthermore, seroprevalence levels in ...

Mouse model of SARS-CoV-2 reveals inflammatory role of type I interferon signaling.
https://doi.org/10.1084/jem.20201241
The Journal of Experimental Medicine; Israelow B, Song E et. al.

Aug 4th, 2020 - Severe acute respiratory syndrome-coronavirus 2 (SARS-Cov-2) has caused over 13,000,000 cases of coronavirus disease (COVID-19) with a significant fatality rate. Laboratory mice have been the stalwart of therapeutic and vaccine development; however, they do not support infection by SARS-CoV-2 due to the virus's inability to use the mouse orthologue of its human entry receptor angiotensin-conver...

Return to School for Pediatric Solid Organ Transplant Recipients in the United States D...
https://doi.org/10.1093/jpids/piaa095
Journal of the Pediatric Infectious Diseases Society; Downes KJ, Danziger-Isakov LA et. al.

Aug 4th, 2020 - The COVID-19 pandemic has created many challenges for pediatric solid organ transplant (SOT) recipients and their families. As the pandemic persists, patients and their families struggle to identify the best and safest practices for resuming activities as areas re-open. In particular, decisions about returning to school remain difficult. We assembled a team of pediatric infectious diseases, tra...

Approaches to screening for hyperglycaemia in pregnant women during and after the COVID...
https://doi.org/10.1111/dme.14380
Diabetic Medicine : a Journal of the British Diabetic Association; Meek CL, Lindsay RS et. al.

Aug 4th, 2020 - To evaluate the diagnostic and prognostic performance of alternative diagnostic strategies to oral glucose tolerance tests, including random plasma glucose, fasting plasma glucose and HbA1c , during the COVID-19 pandemic. Retrospective service data (Cambridge, UK; 17 736 consecutive singleton pregnancies, 2004-2008; 826 consecutive gestational diabetes pregnancies, 2014-2019) and 361 women with...

Review on the coronavirus disease (COVID-19) pandemic: its outbreak and current status.
https://doi.org/10.1111/ijcp.13637
International Journal of Clinical Practice; Almaghaslah D, Kandasamy G et. al.

Aug 4th, 2020 - In late December 2019 and on 1st January 2020, the coronavirus (COVID-19) infecting humans was first identified in Wuhan, Hubei Province, China. Later cases have also been confirmed worldwide. Coronaviruses are RNA viruses that are phenotypically and genotypically diverse. Globally, as of 6th April 2020, laboratory confirmed cases of COVID-19 reported to the World Health Organization (WHO) amou...

Corticosteroid, oseltamivir, and delayed admission are independent risk factors for pro...
https://doi.org/10.1111/crj.13243
The Clinical Respiratory Journal; Hu F, Yin G et. al.

Aug 4th, 2020 - Coronavirus Disease 2019 (COVID-19) has spread worldwide, and it has reached to more than 14.5 million cases. Although Hubei province is the epicenter of China, little is known about epidemiological and clinical features of COVID-19 in other areas in Hubei province around Wuhan. In addition, the virological data, particularly the factors associated with viral shedding of COVID-19 has not been w...

Rationale for Medium Cutoff Membranes in COVID-19 Patients Requiring Renal Replacement ...
https://doi.org/10.1159/000509807
Nephron Ronco C, Reis T et. al.

Aug 4th, 2020 - The current pandemic of coronavirus disease 2019 (COVID-19) spotlighted the vulnerability of patients with chronic kidney disease stage 5 on maintenance hemodialysis (HD) to the viral infection. Social distancing is the most effective preventive measure to reduce the risk of infection. Nonetheless, the necessity to frequently reach the dialysis center and the inherent social gathering both impe...

COVID-19 and the Field of Intellectual and Developmental Disabilities: Where Have We Be...
https://doi.org/10.1352/1934-9556-58.4.257
Intellectual and Developmental Disabilities; Thompson JR, Nygren MA

Aug 4th, 2020 - The coronavirus (COVID-19) pandemic has affected, and will continue to affect, every aspect of the intellectual and developmental disabilities (IDD) community. We provide recommendations to (a) support people with IDD and the broader of field of IDD during the course of the pandemic, and (b) place the IDD community in a strong position when the health threats associated with the pandemic abate ...

The COVID-19 pandemic and patients with endometriosis: A survey-based study conducted i...
https://doi.org/10.1002/ijgo.13339
International Journal of Gynaecology and Obstetrics: the Official Organ of the International Federation of Gynaecology and Obstetrics; Bahat PY, Kaya C et. al.

Aug 4th, 2020 - To apply rapid online surveying to determine the knowledge and perceptions of the COVID-19 pandemic on patients with endometriosis in Turkey. An online survey was conducted by the Turkish Endometriosis & Adenomyosis Society and administered to patients with endometriosis who agreed to participate in the study. The survey included 25 questions prepared by an expert committee of four professional...

Changes in the Number of US Patients With Newly Identified Cancer Before and During the...
https://doi.org/10.1001/jamanetworkopen.2020.17267
JAMA Network Open; Kaufman HW, Chen Z et. al.

Aug 4th, 2020 - Changes in the Number of US Patients With Newly Identified Cancer Before and During the Coronavirus Disease 2019 (COVID-19) Pandemic.|2020|Kaufman HW,Chen Z,Niles J,Fesko Y,|

Prevalence of Health Care Worker Burnout During the Coronavirus Disease 2019 (COVID-19)...
https://doi.org/10.1001/jamanetworkopen.2020.17271
JAMA Network Open; Matsuo T, Kobayashi D et. al.

Aug 4th, 2020 - Prevalence of Health Care Worker Burnout During the Coronavirus Disease 2019 (COVID-19) Pandemic in Japan.|2020|Matsuo T,Kobayashi D,Taki F,Sakamoto F,Uehara Y,|

Suppressed anti-inflammatory heat shock response in high-risk COVID-19 patients: lesson...
https://doi.org/10.1042/CS20200596
Clinical Science (London, England : 1979); Heck TG, Ludwig MS et. al.

Aug 4th, 2020 - The major risk factors to fatal outcome in COVID-19 patients, i.e., elderliness and pre-existing metabolic and cardiovascular diseases (CVD), share in common the characteristic of being chronic degenerative diseases of inflammatory nature associated with defective heat shock response (HSR). The molecular components of the HSR, the principal metabolic pathway leading to the physiological resolut...

Correction to Data in Trial of Convalescent Plasma Treatment for COVID-19.
https://doi.org/10.1001/jama.2020.13216
JAMA

Aug 4th, 2020 - Correction to Data in Trial of Convalescent Plasma Treatment for COVID-19.|2020||

COVID-19 and Massive Job Losses Will Test the US Health Insurance Safety Net.
https://doi.org/10.1001/jama.2020.12248
JAMA Levitt L

Aug 4th, 2020 - COVID-19 and Massive Job Losses Will Test the US Health Insurance Safety Net.|2020|Levitt L,|

Errors in Trial of Effect of Convalescent Plasma Therapy on Time to Clinical Improvemen...
https://doi.org/10.1001/jama.2020.12607
JAMA Liu Z

Aug 4th, 2020 - Errors in Trial of Effect of Convalescent Plasma Therapy on Time to Clinical Improvement in Patients With Severe and Life-threatening COVID-19.|2020|Liu Z,|

The Development of COVID-19 Vaccines: Safeguards Needed.
https://doi.org/10.1001/jama.2020.12461
JAMA Lurie N, Sharfstein JM et. al.

Aug 4th, 2020 - The Development of COVID-19 Vaccines: Safeguards Needed.|2020|Lurie N,Sharfstein JM,Goodman JL,|

Communicating Science in the Time of a Pandemic.
https://doi.org/10.1001/jama.2020.12535
JAMA Saitz R, Schwitzer G

Aug 4th, 2020 - Communicating Science in the Time of a Pandemic.|2020|Saitz R,Schwitzer G,|

Reply to: Does Vaping Increase Susceptibility to COVID-19?
https://doi.org/10.1164/rccm.202006-2351LE
American Journal of Respiratory and Critical Care Medicine; Zhang H, Rostami MR et. al.

Aug 4th, 2020 - Reply to: Does Vaping Increase Susceptibility to COVID-19?|2020|Zhang H,Rostami MR,Leopold PL,Mezey JG,O'Beirne SL,|

Does Vaping Increase Susceptibility to COVID-19?
https://doi.org/10.1164/rccm.202005-2103LE
American Journal of Respiratory and Critical Care Medicine; Sharma P, Zeki AA

Aug 4th, 2020 - Does Vaping Increase Susceptibility to COVID-19?|2020|Sharma P,Zeki AA,|

Resolution of coronavirus disease 2019 (COVID-19).
https://doi.org/10.1080/14787210.2020.1797487
Expert Review of Anti-infective Therapy; Habas K, Nganwuchu C et. al.

Aug 4th, 2020 - Coronavirus disease 2019 (COVID-19) was first detected in China in December, 2019, and declared as a pandemic by the World Health Organization (WHO) on March 11, 2020. The current management of COVID-19 is based generally on supportive therapy and treatment to prevent respiratory failure. The effective option of antiviral therapy and vaccination are currently under evaluation and development. A...

COVID-19 and Cancer Care: Ensuring Safety While Transforming Care Delivery.
https://doi.org/10.1200/JCO.20.01474
Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology; Mulvey TM, Jacobson JO

Aug 4th, 2020 - COVID-19 and Cancer Care: Ensuring Safety While Transforming Care Delivery.|2020|Mulvey TM,Jacobson JO,|

The pursuit of cures for cerebral disease persists, even through a pandemic.
https://doi.org/10.1080/01616412.2020.1778995
Neurological Research; Stone C, Geng X et. al.

Aug 4th, 2020 - The pursuit of cures for cerebral disease persists, even through a pandemic.|2020|Stone C,Geng X,Ding Y,|

SARS-CoV-2 Virus Culture and Subgenomic RNA for Respiratory Specimens from Patients wit...
https://doi.org/10.3201/eid2611.203219
Emerging Infectious Diseases; Perera RAPM, Tso E et. al.

Aug 4th, 2020 - We investigated 68 respiratory specimens from 35 coronavirus disease patients in Hong Kong, of whom 32 had mild disease. We found that severe acute respiratory syndrome coronavirus 2 and subgenomic RNA were rarely detectable beyond 8 days after onset of illness. However, virus RNA was detectable for many weeks by reverse transcription PCR.

Covid-19-Beyond virology: Potentials for maintaining mental health during lockdown.
https://doi.org/10.1371/journal.pone.0236688
PloS One; Munk AJL, Schmidt NM et. al.

Aug 4th, 2020 - The current study aimed to assess prevalence of mental disorders during Covid-19 pandemic- and respective lockdown in Germany, and potential behaviors/states that can have protective functions on preventing severe mental problems. Assessing prevalence of mental disorders, as well as to find potential protective variables is very important in order to determine people's psychological suffering. ...

Naturally occurring SARS-CoV-2 gene deletions close to the spike S1/S2 cleavage site in...
https://doi.org/10.1080/22221751.2020.1806735
Emerging Microbes & Infections; Andres C, Garcia-Cehic D et. al.

Aug 4th, 2020 - The SARS-CoV-2 spike (S) protein, the viral mediator for binding and entry into the host cell, has sparked great interest as a target for vaccine development and treatments with neutralizing antibodies. Initial data suggest that the virus has low mutation rates, but its large genome could facilitate recombination, insertions, and deletions, as has been described in other coronaviruses. Here, we...

BET 1: The role of remdesivir in COVID-19 infection.
https://doi.org/10.1136/emermed-2020-210336.02
Emergency Medicine Journal : EMJ; Baombe JP

Aug 4th, 2020 - A short-cut review of the available medical literature was carried out to establish whether remdesivir was an effective treatment for patients with confirmed COVID-19 infection. After abstract review, five papers were found to answer this clinical question using the detailed search strategy. The author, date and country of publication, patient group studied, study type, relevant outcomes, resul...

"It's like Fighting a War with Rocks:" Nursing Home Healthcare Workers' Experiences Dur...
https://doi.org/10.1017/ice.2020.393
Infection Control and Hospital Epidemiology; Seshadri S, Concannon C et. al.

Aug 4th, 2020 - "It's like Fighting a War with Rocks:" Nursing Home Healthcare Workers' Experiences During COVID-19.|2020|Seshadri S,Concannon C,Woods JA,McCullough K,Dumyati G,|

Neurological and Neuropsychiatric Impacts of COVID-19 Pandemic.
https://doi.org/10.1017/cjn.2020.173
The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques; Roy D, Ghosh R et. al.

Aug 4th, 2020 - Neurological and Neuropsychiatric Impacts of COVID-19 Pandemic.|2020|Roy D,Ghosh R,Dubey S,Dubey MJ,Benito-León J,|

Is Nigeria really on top of COVID-19? Message from effective reproduction number.
https://doi.org/10.1017/S0950268820001740
Epidemiology and Infection; Adekunle AI, Adegboye OA et. al.

Aug 4th, 2020 - Is Nigeria really on top of COVID-19? Message from effective reproduction number.|2020|Adekunle AI,Adegboye OA,Gayawan E,McBryde ES,|

The Telemedicine Musculoskeletal Examination.
https://doi.org/10.1016/j.mayocp.2020.05.026
Mayo Clinic Proceedings; Laskowski ER, Johnson SE et. al.

Aug 4th, 2020 - Telemedicine uses modern telecommunication technology to exchange medical information and provide clinical care to individuals at a distance. Initially intended to improve health care for patients in remote settings, telemedicine now has a broad clinical scope with the general purpose of providing convenient, safe, and time- and cost-efficient care. The coronavirus disease 2019 pandemic has cre...

Reduction in Skin Cancer Diagnoses in the UK during COVID-19 Pandemic.
https://doi.org/10.1111/ced.14411
Clinical and Experimental Dermatology; Andrew TW, Alrawi M et. al.

Aug 4th, 2020 - The UK healthcare system has been profoundly affected by the COVID-19 Pandemic, including skin cancer departments. Despite service capacity and a worldwide increase in incidence, anecdotal reports suggest a decline in skin cancer diagnoses following COVID-19. To determine if there is a decrease in skin cancer diagnosis in the UK in the COVID-19 era, we analysed data from the Northern Cancer Net...

Inpatient Care during the COVID-19 Pandemic: A Survey of Italian Physicians.
https://doi.org/10.1159/000509007
Respiration; International Review of Thoracic Diseases; Attanasi M, Pasini S et. al.

Aug 4th, 2020 - Coronavirus disease 2019 (COVID-19) is a potentially fatal disease that is of great global public health concern. We explored the clinical management of inpatients with COVID-19 in Italy. A self-administered survey was sent by email to Italian physicians caring for adult patients with COVID-19. A panel of experts was selected according to their clinical curricula and their responses were analyz...

Correction to: Guidance on Short-Term Management of Atrial Fibrillation in Coronavirus ...
https://doi.org/10.1161/JAHA.119.014579
Journal of the American Heart Association;

Aug 4th, 2020 - Correction to: Guidance on Short-Term Management of Atrial Fibrillation in Coronavirus Disease 2019.|2020||

Telemedicine in Gastroenterology in the Wake of COVID-19.
https://doi.org/10.1080/17474124.2020.1806056
Expert Review of Gastroenterology & Hepatology; George LA, Cross RK

Aug 4th, 2020 - Telemedicine in Gastroenterology in the Wake of COVID-19.|2020|George LA,Cross RK,|

SARS-CoV-2 mRNA vaccine design enabled by prototype pathogen preparedness.
https://doi.org/10.1038/s41586-020-2622-0
Nature Corbett KS, Edwards DK et. al.

Aug 4th, 2020 - A vaccine for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is needed to control the global coronavirus infectious disease (COVID-19) public health crisis. Atomic-level structures directed the application of prefusion-stabilizing mutations that improved the expression and immunogenicity of betacoronavirus spike proteins1. Using this established immunogen design, the release of SA...

Public perspectives on protective measures during the COVID-19 pandemic in the Netherla...
https://doi.org/10.1371/journal.pone.0236917
PloS One; Meier K, Glatz T et. al.

Aug 4th, 2020 - The extent to which people implement government-issued protective measures is critical in preventing further spread of coronavirus disease 2019 (COVID-19) caused by coronavirus SARS-CoV-2. Our study aimed to describe the public belief in the effectiveness of protective measures, the reported implementation of these measures, and to identify communication channels used to acquire information on ...

Assay validation and determination of in vitro binding of mefloquine to plasma proteins...
https://doi.org/10.1371/journal.pone.0236754
PloS One; Izes AM, Kimble B et. al.

Aug 4th, 2020 - The antimalarial agent mefloquine is currently being investigated for its potential to inhibit feline coronavirus and feline calicivirus infections. A simple, high pressure liquid chromatography assay was developed to detect mefloquine plasma concentrations in feline plasma. The assay's lower limit of quantification was 250 ng/mL. The mean ± standard deviation intra- and inter-day precision exp...

SARS-CoV-2 detection in setting of viral swabs scarcity: Are MRSA swabs and viral swabs...
https://doi.org/10.1371/journal.pone.0237127
PloS One; Federman DG, Gupta S et. al.

Aug 4th, 2020 - The global pandemic of Severe Acute Respiratory Syndrome-Related Coronavirus 2 (SARS-CoV2) has resulted in unprecedented challenges for healthcare systems. One barrier to widespread testing has been a paucity of traditional respiratory viral swab collection kits relative to the demand. Whether other sample collection kits, such as widely available MRSA nasal swabs can be used to detect SARS-CoV...

Development and simulation of fully glycosylated molecular models of ACE2-Fc fusion pro...
https://doi.org/10.1371/journal.pone.0237295
PloS One; Bernardi A, Huang Y et. al.

Aug 4th, 2020 - We develop fully glycosylated computational models of ACE2-Fc fusion proteins which are promising targets for a COVID-19 therapeutic. These models are tested in their interaction with a fragment of the receptor-binding domain (RBD) of the Spike Protein S of the SARS-CoV-2 virus, via atomistic molecular dynamics simulations. We see that some ACE2 glycans interact with the S fragments, and glycan...

Bayesian inference of COVID-19 spreading rates in South Africa.
https://doi.org/10.1371/journal.pone.0237126
PloS One; Mbuvha R, Marwala T

Aug 4th, 2020 - The Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has highlighted the need for performing accurate inference with limited data. Fundamental to the design of rapid state responses is the ability to perform epidemiological model parameter inference for localised trajectory predictions. In this work, we perform Bayesian parameter inference using Markov Chain Monte Carlo (MC...

Livedoid and Purpuric Skin Eruptions Associated With Coagulopathy in Severe COVID-19.
https://doi.org/10.1001/jamadermatol.2020.2800
JAMA Dermatology; Droesch C, Hoang M et. al.

Aug 4th, 2020 - Livedoid and Purpuric Skin Eruptions Associated With Coagulopathy in Severe COVID-19.|2020|Droesch C,Hoang M,DeSancho M,Lee EJ,Magro C,|

Relationship of George Floyd protests to increases in COVID-19 cases using event study ...
https://doi.org/10.1093/pubmed/fdaa127
Journal of Public Health (Oxford, England); Valentine R, Valentine D et. al.

Aug 4th, 2020 - Protests ignited by the George Floyd incident were examined for any significant impact on COVID-19 infection rates in select US cities. Eight US cities were studied in which protestors in the tens of thousands were reported. Only cities that reside in states whose stay-at-home orders had been rescinded or expired for a minimum of 30 days were included in the sample to account for impact of grow...

Immunity passports to travel during the COVID-19 pandemic: controversies and public hea...
https://doi.org/10.1093/pubmed/fdaa125
Journal of Public Health (Oxford, England); Liew CH, Flaherty GT

Aug 4th, 2020 - As countries emerge from pandemic lockdown, many countries are relaxing international travel restrictions. Commercially available serologic tests for anti-SARS-CoV-2 antibodies are being performed. The concept of an 'immunity passport' has gained popularity, whereby evidence of SARS-CoV-2 antibody production would signal immunity to reinfection. For an immunity certificate to be validated for t...

Loneliness and mental health during the COVID-19 pandemic: A study among Dutch older ad...
https://doi.org/10.1093/geronb/gbaa111
The Journals of Gerontology. Series B, Psychological Sciences and Social Sciences; van Tilburg TG, Steinmetz S et. al.

Aug 4th, 2020 - With the spread of COVID-19, the Netherlands implemented a policy to keep citizens physically distanced. We hypothesize that consequent reduction in the frequency of social contacts, personal losses and the experience of general threats in society reduced well-being. Data were collected from 1,679 Dutch community-dwelling participants aged 65 to 102 years old comprising a longitudinal online pa...

Evaluation of COVID-19 RT-qPCR tests in multi-sample pools.
https://doi.org/10.1093/cid/ciaa1099
Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America; Gang A, Gang J

Aug 4th, 2020 - Evaluation of COVID-19 RT-qPCR tests in multi-sample pools.|2020|Gang A,Gang J,|

The Color of COVID-19: Structural Racism and the Pandemic's Disproportionate Impact on ...
https://doi.org/10.1093/geronb/gbaa114
The Journals of Gerontology. Series B, Psychological Sciences and Social Sciences; Garcia MA, Homan PA et. al.

Aug 4th, 2020 - The aim of this evidence-based theoretically informed essay is to provide an overview of how and why the COVID-19 outbreak is particularly detrimental for the health of older Black and Latinx adults. We draw upon current events, academic literature, and numerous data sources to illustrate how biopsychosocial factors place older adults at higher risk for COVID-19 relative to younger adults, and ...

Incomplete Kawasaki Disease as Presentation of COVID-19 Infection in an Infant: A Case ...
https://doi.org/10.1093/tropej/fmaa047
Journal of Tropical Pediatrics; Raut S, Roychowdhoury S et. al.

Aug 4th, 2020 - Recently a severe form of COVID-19 infection has been described in a cluster of children presenting as multisystem inflammatory condition. One of the important spectrum of this condition is incomplete Kawasaki disease (KD). A 5-month-old male child presented with high-spiking fever for 5 days with skin rash, bilateral non-purulent conjunctivitis and irritability. His C-reactive protein was mark...

Unique SARS-CoV-2 clusters causing a large COVID-19 outbreak in Hong Kong.
https://doi.org/10.1093/cid/ciaa1119
Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America; To KK, Chan WM et. al.

Aug 4th, 2020 - After two months of relative quiescence, a large COVID-19 outbreak occurred in Hong Kong in July 2020 after gradual relaxation of social distancing policy. Two unique SARS-CoV-2 phylogenetic clusters have been identified among locally-acquired cases, with most genomes belonging to cluster HK1 which is phylogenetically related to SARS-CoV-2 reported overseas.

Effect of adult COVID-19 surge on the provision of kidney replacement therapy in children.
https://doi.org/10.1007/s00467-020-04723-z
Pediatric Nephrology (Berlin, Germany); Deep A

Aug 4th, 2020 - Effect of adult COVID-19 surge on the provision of kidney replacement therapy in children.|2020|Deep A,|

Knowledge, Attitudes and Practices of COVID-19 Among Urban and Rural Residents in China...
https://doi.org/10.1007/s10900-020-00877-x
Journal of Community Health; Yue S, Zhang J et. al.

Aug 4th, 2020 - This study aims to understand the knowledge, attitudes and practices of COVID-19 in the Chinese context and to provide insights for developing targeted outbreak prevention and control measures among the general public. We conducted an online survey of urban and rural residents in Henan Province. A total of 517 valid questionnaires were collected via the online platform. The mean scores for know...

Temporal changes in psychobehavioural responses during the early phase of the COVID-19 ...
https://doi.org/10.1007/s10865-020-00172-z
Journal of Behavioral Medicine; Wong LP, Alias H

Aug 4th, 2020 - Monitoring public psychological and behavioural responses during the early phase of the coronavirus disease 2019 (COVID-19) outbreak is important for the management and control of infection. This study aims to investigate the temporal trend in (1) avoidance and protective behaviors, (2) fear, (3) socio-economic impact, and (4) anxiety levels during the early phase of the COVID-19 pandemic. As a...

Coronavirus disease 2019 crisis and intentional injuries: now is not the time to erode ...
https://doi.org/10.17269/s41997-020-00391-6
Canadian Journal of Public Health = Revue Canadienne De Sante Publique; Lange S, Probst C et. al.

Aug 4th, 2020 - In Canada, and elsewhere, the coronavirus disease 2019 (COVID-19) crisis has resulted in a social, economic, and alcohol policy environment that is likely to contribute to a rise in intentional injuries, whether interpersonal or self-directed violence. Heavy drinking has been identified as an important risk factor for intentional injuries, and with the erosion of alcohol control policies on alc...

Long lasting hypercoagulability after subclinical COVID-19.
https://doi.org/10.1007/s11239-020-02215-3
Journal of Thrombosis and Thrombolysis; Ferroli P, Villa C et. al.

Aug 4th, 2020 - Long lasting hypercoagulability after subclinical COVID-19.|2020|Ferroli P,Villa C,Ciuffi A,Gubertini G,Broggi M,|