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First weeks back to school: An uneasy transition
https://www.mdedge.com/pediatrics/article/257001/mental-health/first-weeks-back-school-uneasy-transition
Barbara J. Howard, MD

Aug 12th, 2022 - Parents are relieved when school starts up again in the fall. Kids also are eager to see their friends and go on to the next level of learning.

Several Cities in China Add COVID Curbs as Millions Still Under Lockdown
https://www.medscape.com/viewarticle/979051

Aug 12th, 2022 - Reducing people's unnecessary movement for a few days - a softer type of lockdown - as soon as dozens of new cases emerge is a key practice of China's "dynamic COVID-zero" strategy. The aim is to avoid turning efforts to halt an outbreak into the extended nightmares seen in Shanghai and Wuhan. The uncertainty over how long such smaller lockdowns may last - because Omicron's high transmissibilit...

COVID-19 Reinfections
https://emedicine.medscape.com/article/2500144-overview

Aug 12th, 2022 - Practice Essentials The definition of COVID-19 reinfection has evolved since early 2021. Fundamentally, it describes an infected individual who has been fully vaccinated, with or without a booster or boosters, and who becomes infected with COVID-19 again. The CDC more precisely defines it as COVID-19 infection of a given person with 2 different viral strains occurring at least 45 days apart. Al...

COVID-19 Reinfections
http://emedicine.medscape.com/article/2500144-overview

Aug 12th, 2022 - Practice Essentials The definition of COVID-19 reinfection has evolved since early 2021. Fundamentally, it describes an infected individual who has been fully vaccinated, with or without a booster or boosters, and who becomes infected with COVID-19 again. The CDC more precisely defines it as COVID-19 infection of a given person with 2 different viral strains occurring at least 45 days apart. Al...

COVID-19 Reinfections
https://emedicine.medscape.com/article/2500144-print

Aug 12th, 2022 - The definition of COVID-19 reinfection has evolved since early 2021. Fundamentally, it describes an infected individual who has been fully vaccinated, with or without a booster or boosters, and who becomes infected with COVID-19 again. The CDC more precisely defines it as COVID-19 infection of a given person with 2 different viral strains occurring at least 45 days apart. Alternately, it may re...

Aspen COVID Vaccine Lines Risk Going Idle as J&J Orders Dwindle
https://www.medscape.com/viewarticle/979035

Aug 11th, 2022 - JOHANNESBURG (Reuters) -South Africa's Aspen Pharmacare's COVID-19 vaccine production lines may soon go idle, and without any new orders it could be forced to pivot to manufacturing other products, a senior executive said on Wednesday. Aspen currently produces vaccines for Johnson & Johnson and, in March, it struck a deal to produce, price, and sell its own-brand version of the shot for African...

Latest on the Worldwide Spread of the Coronavirus
https://www.medscape.com/viewarticle/979063

Aug 11th, 2022 - (Reuters) - North Korea's Kim Jong Un declared victory in the battle against COVID-19 on Thursday, with the leader's sister indicating that he too caught the virus while vowing "deadly retaliation" against South Korea which the North blames for causing the outbreak. DEATHS AND INFECTIONS Eikon users, click on COVID-19: MacroVitals for a case tracker and summary of news. cpurl://apps.cp./cms/?na...

FDA Expands Home Testing Guidelines for COVID Exposures
https://www.medscape.com/viewarticle/979100

Aug 11th, 2022 - Editor's note: Find the latest COVID-19 news and guidance in Medscape's Coronavirus Resource Center. It might be a good time to stock up on home COVID-19 tests. Today, the FDA issued new guidance on at-home COVID testing. It still recommends repeat testing after a negative result, but is also recommending that people who have no symptoms but think they have been exposed take three tests instead...

CDC Ends Some COVID Safety Rules, Emphasizes Personal Risk
https://www.medscape.com/viewarticle/979109

Aug 11th, 2022 - Editor's note: Find the latest COVID-19 news and guidance in Medscape's Coronavirus Resource Center. The CDC today announced that because the risk of "medically significant" COVID-19 has decreased, some overall public health measures the agency initially recommended may no longer be necessary. For example, CDC recommendations on social distancing, quarantining and testing children for COVID-19 ...

CDC Says More Is Needed to Protect Infants From Hepatitis B
https://www.medscape.com/viewarticle/979110

Aug 11th, 2022 - Progress has occurred in reducing maternal-to-child transmission of hepatitis B but is still lagging, particularly in Africa, according to a recent report from the Centers for Disease Control and Prevention (CDC) on maternal-to-child transmission (MTCT) of hepatitis B virus (HBV). By December 2020, 190 (98%) of 194 World Health Organization (WHO) member states had introduced universal infant va...

Large Study Confirms COVID Vaccines Safe for Pregnant Women
https://www.medscape.com/viewarticle/979114

Aug 11th, 2022 - Pregnant women should feel confident that Pfizer's and Moderna's vaccines against COVID-19 are safe, according to a large new study published today. In fact, pregnant vaccinated women had lower odds of a significant health event, compared with nonpregnant vaccinated women, after both doses of either mRNA vaccination, the researchers reported in the journal The Lancet Infectious Diseases. This s...

German Officials Resist Call to End Quarantine Requirement
https://www.medscape.com/viewarticle/979070

Aug 11th, 2022 - During the surge in coronavirus infections this summer, the chief executive of the German National Association of Statutory Health Insurance Physicians (KBV), Andreas Gassen, MD, called for the isolation and quarantine requirement to be lifted for people infected with the coronavirus. "We cannot hide from the virus forever. We have to return to normality. If you are ill, stay at home. If you fe...

Alcohol-Associated Liver Disease Soared With COVID-19
https://www.medscape.com/viewarticle/979054

Aug 11th, 2022 - Alcohol abuse and the liver disease that results from it both accelerated during the COVID-19 pandemic, a review of the research shows. The emotional stress and social isolation of the pandemic combined with reduced access to mental health services worsened trends in alcohol-related disease, according to lead author Sasha Deutsch-Link, MD, a gastroenterology fellow at the University of North Ca...

Plasma Biomarkers Predict COVID Neurologic Complications
https://www.medscape.com/viewarticle/979083

Aug 11th, 2022 - SAN DIEGO – Even after recovery of an acute COVID-19 infection, some patients experience extended or even long-term symptoms that can range from mild to debilitating. Some of these symptoms are neurological: headaches, brain fog, cognitive impairment, loss of taste or smell, and even cerebrovascular complications such stroke. There are even hints that COVID-19 infection could lead to future neu...

Study: Long COVID Patients Have Immune System Differences
https://www.medscape.com/viewarticle/979097

Aug 11th, 2022 - Editor's note: Find the latest COVID-19 news and guidance in Medscape's Coronavirus Resource Center. Using immune profiling, a small but intense study found that people with long COVID have increased antibody responses to other non-COVID viruses, like Epstein-Barr Virus (EBV), as well as significantly lowered cortisol levels compared with people without long COVID. The study — which is still a ...

Plasma biomarkers predict COVID’s neurological sequelae
https://www.mdedge.com/neurology/article/256960/covid-19-updates/plasma-biomarkers-predict-covids-neurological-sequelae
Jim Kling

Aug 10th, 2022 - SAN DIEGO – Even after recovery of an acute COVID-19 infection, some patients experience extended or even long-term symptoms that can range from mild to debilitating. Some of these symptoms are neurological: headaches, brain fog, cognitive impairment, loss of taste or smell, and even cerebrovascular complications such stroke.

In one state, pandemic tamped down lice and scabies cases
https://www.mdedge.com/dermatology/article/256939/infectious-diseases/one-state-pandemic-tamped-down-lice-and-scabies-cases
Heidi Splete

Aug 10th, 2022 - The incidence of lice and scabies decreased significantly among children and adults in North Carolina during the confinement period of the COVID-19 pandemic, between March 2020 and February 2021, according to a report in Pediatric Dermatology. When COVID-19 was declared a public health emergency by the World Health Organization in March 2020, many countries including the United States enacted l.

Durability of Heterologous and Homologous COVID-19 Vaccine Boosts
https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2794985?resultClick=3
JAMA Network Open; Tan CS, Collier AY et. al.

Aug 10th, 2022 - Messenger RNA (mRNA) vaccines for COVID-19 have demonstrated outstanding short-term immunogenicity and protective efficacy.1,2 However, neutralizing antibody (NAb) responses have been reported to wane by 3 to 6 months after primary immunization.3-7 Following a third mRNA dose, Omicron-specific NAbs were induced,8-11 but these antibody responses and clinical effectiveness also declined after 3 t...

COVID vs Monkeypox: A Tale of Two Pandemics
https://www.medscape.com/viewarticle/978655

Aug 10th, 2022 - Welcome to Impact Factor, your weekly dose of commentary on a new medical study. I'm Dr F. Perry Wilson of the Yale School of Medicine. Toward the end of 2019, we all took a crash course in virology and infectious disease epidemiology as we struggled with what was, for many of us, the first major pandemic of our lifetimes. We've learned a lot since then — we've upped our game when it comes to t...

EU Regulator Begins Review of Pfizer-BioNTech's Variant-Adapted COVID Shot
https://www.medscape.com/viewarticle/978901

Aug 10th, 2022 - LONDON (Reuters) -The European Medicines Agency (EMA) has started a rolling review of a variant-adapted COVID-19 vaccine from Pfizer and BioNTech, it said on Tuesday. The so-called bivalent vaccine targets two strains of the SARS-CoV-2 virus behind COVID - the original strain first identified in China, and the Omicron offshoots BA.4/5 that are currently behind most cases in Europe. A rolling re...

China Races to Contain COVID Outbreaks in Tourism Hubs Tibet, Hainan
https://www.medscape.com/viewarticle/978902

Aug 10th, 2022 - SHANGHAI/BEIJING (Reuters) -China raced on Tuesday to stamp out COVID-19 outbreaks in the tourist hubs of Tibet and Hainan, with the authorities launching more rounds of mass testing and closing venues to contain the highly transmissible Omicron variant. Mainland China reported 828 new domestically transmitted cases across more than a dozen provinces and regions for Aug. 8, with over half of th...

Drugmaker Gilead to Help Fund Monkeypox Education for LGBTQ+ Groups
https://www.medscape.com/viewarticle/978913

Aug 10th, 2022 - (Reuters) - Drugmaker Gilead Sciences plans to announce on Tuesday that it will provide up to $5 million in grants to help a coalition of LGBTQ+ and human rights advocacy groups craft public health responses to monkeypox outbreaks, the company said. Outside of Africa, where the virus is endemic, new cases have largely occurred among gay and bisexual men. Experts warn that the virus could spread...

Children and COVID: Severe Illness Rising as Vaccination Effort Stalls
https://www.medscape.com/viewarticle/979011

Aug 10th, 2022 - Editor's note: Find the latest COVID-19 news and guidance in Medscape's Coronavirus Resource Center. New cases of COVID-19 rose among children for the fourth consecutive week, but the size of the increase declined for the second consecutive week, based on data from the American Academy of Pediatrics and the Children's Hospital Association. After new child cases jumped by 22% during the week of ...

Pandemic Tamped Down Lice and Scabies Cases in North Carolina, Study Finds
https://www.medscape.com/viewarticle/979022

Aug 10th, 2022 - The incidence of lice and scabies decreased significantly among children and adults in North Carolina during the confinement period of the COVID-19 pandemic, between March 2020 and February 2021, according to a report in Pediatric Dermatology. When COVID-19 was declared a public health emergency by the World Health Organization in March 2020, many countries including the United States enacted l...

Regular Fasting Linked to Less Severe COVID: Study
https://www.medscape.com/viewarticle/979036

Aug 10th, 2022 - Editor's note: Find the latest COVID-19 news and guidance in Medscape's Coronavirus Resource Center. Intermittent fasting was not linked with a smaller chance of getting COVID-19, but it was linked with getting a less severe infection, according to the findings of a new study. The study was done on men and women in Utah who were, on average, in their 60s and got COVID before vaccines were avail...

Long COVID's Grip Will Likely Tighten as Infections Continue
https://www.medscape.com/viewarticle/979040

Aug 10th, 2022 - COVID-19 is far from done in the United States, with more than 111,000 new cases being recorded a day in the second week of August, according to Johns Hopkins University, and 625 deaths being reported every day. And as that toll grows, experts are worried about a second wave of illnesses from long COVID, a condition that already has affected between 7.7 million and 23 million Americans, accordi...

Biden Now Has Cough, but Not COVID
https://www.medscape.com/viewarticle/979038

Aug 10th, 2022 - Editor's note: Find the latest COVID-19 news and guidance in Medscape's Coronavirus Resource Center. President Joe Biden continues to test negative for COVID-19 but has a lingering effect of the virus, namely a cough. Biden coughed several times during a speech on the South Lawn of the White House on Tuesday, which made him stop a few times and turn his head or sip water, according to Reuters. ...

Climate Change Puts Lyme Disease in Focus for France's Valneva After COVID Blow
https://www.medscape.com/viewarticle/978788

Aug 10th, 2022 - LONDON (Reuters) - With climate change spurring more cases of tick-borne Lyme disease, drugmaker Valneva is betting big on a vaccine as it looks beyond disappointing sales of its COVID shot. Although Valneva secured European Union and British regulatory approval, both walked away from contracts worth more than a billion dollars combined, wiping nearly 40% off the value of Valneva's share price ...

Physicians React: Mistakes and Successes in Building Wealth
https://www.medscape.com/viewarticle/979000

Aug 10th, 2022 - 2021 was a transitional year, with physicians still reeling from the financial effects of the COVID-19 pandemic. Fortunately, physicians' average compensation rose and their financial prospects began to brighten, as noted in the Medscape Physician Wealth & Debt Report 2022. Respondents' comments in the survey and readers' comments on the results humanize the trends affecting physicians' family ...

Will ‘Centaurus’ be the next global coronavirus variant? Indian cases offers clues
https://www.nature.com/articles/d41586-022-02154-4
Nature Callaway E.

Aug 10th, 2022 - As countries await the end of COVID-19 surges caused by the variant BA.5, researchers are on the lookout for what will come next. An Omicron subvariant called BA.2.75 — and nicknamed ‘Centaurus’ by some on social media — is rising fast in India. A few scientists are sounding the alarm, whereas others say it’s too early to tell whether the variant will spread widely. In India, it doesn’t yet ...

Long-term quality of life impairment in patients with more than one-year COVID-19-relat...
https://doi.org/10.1002/alr.23071
International Forum of Allergy & Rhinology; Pendolino AL, Tan HQM et. al.

Aug 10th, 2022 - Long-term quality of life impairment in patients with more than one-year COVID-19-related olfactory dysfunction.|2022|Pendolino AL,Tan HQM,Choi D,Ottaviano G,Andrews PJ,|

To Wait or Not to Wait? Covid-19 Vaccination Mitigates Adverse Surgical Outcomes.
https://doi.org/10.1097/SLA.0000000000005675
Annals of Surgery; Baiu I, Hawn M

Aug 10th, 2022 - To Wait or Not to Wait? Covid-19 Vaccination Mitigates Adverse Surgical Outcomes.|2022|Baiu I,Hawn M,|

Impact Factor JUMPS After the 2020 COVID-19 Pandemic: A Retrospective Study in Radiolog...
https://doi.org/10.1097/RUQ.0000000000000615
Ultrasound Quarterly; Garcia-Blanco MD, Valdez-Valdes A et. al.

Aug 10th, 2022 - One of the most widely applied methods for evaluating a research paper's quality is the impact factor (IF). The term JUMPS was applied to the IF in an article published in PubMed in 2021, describing an increase of more than 40% of IF. In this study, we aimed to compare the growth rate of IF JUMPS in Radiology, Nuclear Medicine & Medical Imaging in the last 6 years. This retrospective study calc...

Factors associated with severe or fatal clinical manifestations of SARS-CoV-2 infection...
https://doi.org/10.1111/joim.13551
Journal of Internal Medicine; Corrao G, Franchi M et. al.

Aug 10th, 2022 - Little is known about vulnerability to severe COVID-19 illness after vaccination completion with three doses of vaccine against COVID-19. To identify individual features associated with increased risk of severe clinical manifestation of SARS-CoV-2 infections after receiving the third dose of vaccine against COVID-19. We performed a nested case-control study based on 3,360,116 citizens from Lomb...

Retrobulbar Injection of Amphotericin B in Patients With COVID-19 Associated Orbital Mu...
https://doi.org/10.1097/IOP.0000000000002256
Ophthalmic Plastic and Reconstructive Surgery; Sharifi A, Akbari Z et. al.

Aug 10th, 2022 - Following COVID-19 infection a rising count of rhino-orbito-cerebral mucormycosis is observed, requiring orbital exenteration, a disabling lifetime affecting surgery. One of the potential interventions for globe salvage in these patients is retrobulbar injections of amphotericin B. This study was conducted to review protocols, outcomes, and side effects of retrobulbar injection of amphotericin ...

Between a Rock and a Hard Place: The Challenges of Caregiving During a Pandemic for Par...
https://doi.org/10.1177/10499091221119462
The American Journal of Hospice & Palliative Care; Seshadri S, Norton SA et. al.

Aug 10th, 2022 - Aim: To understand Parkinson's Disease (PD) care partners' a) specific challenges that led to worsening strain and b) their suggestions for supports to help them during the ongoing pandemic. Method: Using a qualitative descriptive design, semi-structured interviews with family care partners (n = 19) were completed. Participants were recruited from 10 sites across the United States that varied i...

The spike receptor-binding motif G496S substitution determines the replication fitness ...
https://doi.org/10.1080/22221751.2022.2111977
Emerging Microbes & Infections; Liang R, Ye ZW et. al.

Aug 10th, 2022 - AbstractThe replication and pathogenicity of SARS-CoV-2 Omicron BA.2 is comparable to that of BA.1 in experimental animal models. However, BA.2 has rapidly emerged to overtake BA.1 to become the predominant circulating SARS-CoV-2 variant worldwide. Here, we compared the replication fitness of BA.1 and BA.2 in cell culture and in the Syrian hamster model of COVID-19. Using a reverse genetics app...

NVX-CoV2373 vaccination induces functional SARS-CoV-2-specific CD4+ and CD8+ T cell res...
https://doi.org/10.1172/JCI160898
The Journal of Clinical Investigation; Rydyznski Moderbacher C, Kim CJ et. al.

Aug 10th, 2022 - NVX-CoV2373 is an adjuvanted recombinant full-length SARS-CoV-2 spike trimer protein vaccine demonstrated to be protective against COVID-19 in efficacy trials. Here we demonstrate that vaccinated subjects made CD4+ T cell responses after one and two doses of NVX-CoV2373, and a subset of individuals made CD8+ T cell responses. Characterization of the vaccine-elicited CD8+ T cells demonstrated IF...

Computational Scientific Discovery in Psychology.
https://doi.org/10.1177/17456916221091833
Perspectives on Psychological Science : a Journal of the ... Bartlett LK, Pirrone A et. al.

Aug 10th, 2022 - Scientific discovery is a driving force for progress involving creative problem-solving processes to further our understanding of the world. The process of scientific discovery has historically been intensive and time-consuming; however, advances in computational power and algorithms have provided an efficient route to make new discoveries. Complex tools using artificial intelligence (AI) can e...

Seizures following COVID-19 vaccination in Mexico: a nationwide observational study.
https://doi.org/10.1111/epi.17390
Epilepsia Núñez I, García-Grimshaw M et. al.

Aug 10th, 2022 - The COVID-19 pandemic led to the development and emergency approval of an array of effective vaccines against SARS-CoV-2. Given the relatively small number of patients included in vaccine trials, post-approval epidemiological surveillance is crucial to detect infrequent vaccine-related adverse events. We conducted a nationwide retrospective descriptive study evaluating the incidence of seizures...

Rural-Urban Differences in the Associations Between Aging and Disability Services and C...
https://doi.org/10.1177/07334648221119457
Journal of Applied Gerontology : the Official Journal of ... Sun Y, Rhubart DC

Aug 10th, 2022 - Aging services were poised to play an important role in supporting the COVID-19 vaccination rollout for older adults. In this study, we use ordinary least squares regression models of county-level data (N = 3086) to examine if density of aging and disability services is associated with COVID-19 vaccination rates for older adults in rural and urban areas of the United States. We find that net of...

Palliative paramedicine: Comparing clinical practice through guideline quality appraisa...
https://doi.org/10.1177/02692163221110419
Palliative Medicine; Juhrmann ML, Anderson NE et. al.

Aug 10th, 2022 - Palliative care is an emerging scope of practice for paramedicine. The COVID-19 pandemic has highlighted the opportunity for emergency settings to deliver palliative and end-of-life care to patients wishing to avoid intensive life-sustaining treatment. However, a gap remains in understanding the scope and limitations of current ambulance services' approach to palliative and end-of-life care. To...

Telemedicine for Children With Medical Complexity During the COVID-19 Pandemic: Implica...
https://doi.org/10.1177/00099228221116707
Clinical Pediatrics; Lakhaney D, Matiz LA

Aug 10th, 2022 - Telemedicine for Children With Medical Complexity During the COVID-19 Pandemic: Implications for Practice.|2022|Lakhaney D,Matiz LA,|

Extrapulmonary Manifestations of SARS-CoV-2: A Report of 3 Cases and a Literature Review.
https://doi.org/10.12659/AOT.935874
Annals of Transplantation; Barbachowska A, Gozdowska J et. al.

Aug 10th, 2022 - BACKGROUND COVID-19 disease, caused by the SARS-CoV-2 virus, has been one of the greatest challenges in modern medicine. It is mostly known to affect the pulmonary system, leading to pneumonia and acute respiratory distress syndrome, but there is a growing body of evidence of extrapulmonary manifestations of COVID-19 disease. CASE REPORT This article presents 3 cases of various extrapulmonary s...

Update on Staphylococcus aureus bacteraemia.
https://doi.org/10.1097/MCC.0000000000000974
Current Opinion in Critical Care; Tabah A, Laupland KB

Aug 10th, 2022 - To review recently published evidence relevant to Staphylococcus aureus bacteremia (SAB). Staphylococcus aureus is the most common pathogen causing co-infections and superinfections in patients with COVID-19. Methicillin-resistant Staphylococcus aureus (MRSA) bacteremia ratios have sharply risen during the pandemic. SAB mortality is 18% at 1 month and 27% at 3 months but has gradually decreased...

A Framework for Pediatric Health Care Providers to Promote Active Play in Nature for Ch...
https://doi.org/10.1177/21501319221114842
Journal of Primary Care & Community Health; Tandon PS, Hafferty K et. al.

Aug 10th, 2022 - Time outdoors and contact with nature are positively associated with a broad range of children's health outcomes. Pediatricians are uniquely positioned to promote active play in nature (APN) but may face challenges to do so during well child visits. The objective of this study was to understand barriers to children's APN, before and during the COVID-19 pandemic, and how health care providers co...

Lulled into a false sense of security: Mortality for vulnerable populations may remain ...
https://doi.org/10.1002/jhm.12934
Journal of Hospital Medicine; Sata SS, Greysen SR

Aug 10th, 2022 - Lulled into a false sense of security: Mortality for vulnerable populations may remain elevated even during the lull between COVID-19 waves.|2022|Sata SS,Greysen SR,|

Immunity after COVID-19 vaccination in people with higher risk of compromised immune st...
https://doi.org/10.1002/14651858.CD015021
The Cochrane Database of Systematic Reviews; Kreuzberger N, Hirsch C et. al.

Aug 10th, 2022 - High efficacy in terms of protection from severe COVID-19 has been demonstrated for several SARS-CoV-2 vaccines. However, patients with compromised immune status develop a weaker and less stable immune response to vaccination. Strong immune response may not always translate into clinical benefit, therefore it is important to synthesise evidence on modified schemes and types of vaccination in th...

Preeclampsia and severe acute respiratory syndrome coronavirus 2 infection: a systemati...
https://doi.org/10.1097/HJH.0000000000003213
Journal of Hypertension; Tossetta G, Fantone S et. al.

Aug 10th, 2022 - Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the cause of the coronavirus disease 2019 (COVID-19) disease that has rapidly spread worldwide, causing hundreds of thousand deaths. Normal placentation is characterized by many processes strictly regulated during pregnancy. If placentation is impaired, it can lead to gestational disorders, such as preeclampsia that is a multisyste...

Impact of COVID-19 on the food security and identifying the compromised food security d...
https://doi.org/10.1371/journal.pone.0272859
PloS One; Gebeyehu DT, East L et. al.

Aug 10th, 2022 - Food security is substantially affected directly by COVID-19 and/or indirectly by the measures adopted for the prevention of COVID-19 transmission. The aim of this systematic review is to summarize the impact of COVID-19 on food security and identify the most compromised food security dimension to ease the food security regulators and actors' intervention prioritisation. Primary research focuse...

Global patterns of antigen receptor repertoire disruption across adaptive immune compar...
https://doi.org/10.1073/pnas.2201541119
Proceedings of the National Academy of Sciences of the Un... Joseph M, Wu Y et. al.

Aug 10th, 2022 - Whereas pathogen-specific T and B cells are a primary focus of interest during infectious disease, we have used COVID-19 to ask whether their emergence comes at a cost of broader B cell and T cell repertoire disruption. We applied a genomic DNA-based approach to concurrently study the immunoglobulin-heavy (IGH) and T cell receptor (TCR) β and δ chain loci of 95 individuals. Our approach detecte...

Plasma metabolome and cytokine profile reveal glycylproline modulating antibody fading ...
https://doi.org/10.1073/pnas.2117089119
Proceedings of the National Academy of Sciences of the Un... Yang Z, Wu D et. al.

Aug 10th, 2022 - The COVID-19 pandemic has incurred tremendous costs worldwide and is still threatening public health in the "new normal." The association between neutralizing antibody levels and metabolic alterations in convalescent patients with COVID-19 is still poorly understood. In the present work, we conducted absolutely quantitative profiling to compare the plasma cytokines and metabolome of ordinary co...

Global burden of SARS-CoV-2 infection, hospitalization and case fatality rate among COV...
https://doi.org/10.1371/journal.pone.0272839
PloS One; Nka AD, Ka'e AC et. al.

Aug 10th, 2022 - COVID-19 has been the most important public health concern worldwide since 2020. Several vaccines are now available to help in controlling COVID-19 associated morbidity and mortality. This study will aim to provide the global and regional prevalence of SARS-CoV-2 infection as well as an estimate of disease severity among COVID-19 vaccinated individuals. In order to determine the global burden o...

Stressors, manifestations and course of COVID-19 related distress among public sector n...
https://doi.org/10.1371/journal.pone.0271824
PloS One; Marsden KM, Robertson IK et. al.

Aug 10th, 2022 - Impacts of the COVID-19 pandemic on the mental health of healthcare workers has been established, linking workplace factors with high levels of stress, anxiety, depression, insomnia and burnout. Less established is how COVID-19 affects both work, home and social life of nurses and midwives concurrently. This study describes the prevalence and severity of anxiety, depression, post-traumatic stre...

Risk factors of SARS-CoV-2 infection in cancer patients pre- and post-vaccination.
https://doi.org/10.1371/journal.pone.0272869
PloS One; Alsagaby SA, Alharbi NK et. al.

Aug 10th, 2022 - Severe complications from COVID-19 and poor responses to SARS-CoV-2 vaccination were commonly reported in cancer patients compared to those without cancer. Therefore, the identification of predisposing factors to SARS-CoV-2 infection in cancer patients would assist in the prevention of COVID-19 and improve vaccination strategies. The literature lacks reports on this topic from the Kingdom of Sa...

Allosteric Binding Sites of the SARS-CoV-2 Main Protease: Potential Targets for Broad-S...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9356625
Drug Design, Development and Therapy; Alzyoud L, Ghattas MA et. al.

Aug 10th, 2022 - The current pandemic caused by the COVID-19 disease has reached everywhere in the world and has affected every aspect of our lives. As of the current data, the World Health Organization (WHO) has reported more than 300 million confirmed COVID-19 cases worldwide and more than 5 million deaths. Mpro is an enzyme that plays a key role in the life cycle of the SARS-CoV-2 virus, and it is vital for ...

Jetstream Atherectomy Followed by Paclitaxel-Coated Balloons versus Balloon Angioplasty...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9356602
Vascular Health and Risk Management; Shammas NW, Purushottam B et. al.

Aug 10th, 2022 - It is unknown at this time whether Jetstream atherectomy (JET) and paclitaxel-coated balloon (PCB) provides a superior outcome to balloon angioplasty (PTA) followed by PCB in treating femoropopliteal (FP) arterial disease. The JET-RANGER study was a multicenter (eleven US centers) randomized trial, core lab-adjudicated, designed to demonstrate the superiority of JET + PCB versus PTA + PCB in tr...

Effectiveness and Safety of Enoxaparin Versus Unfractionated Heparin as Thromboprophyla...
https://doi.org/10.1177/10600280221115299
The Annals of Pharmacotherapy; AlLehaibi LH, Alomar M et. al.

Aug 10th, 2022 - Coronavirus 2019 (COVID-19) patients are at risk of thrombosis. Literature that compares the effectiveness of enoxaparin to unfractionated heparin (UFH) in COVID-19 patients is scarce. We aimed to evaluate the effectiveness and safety of enoxaparin compared with UFH when used at their standard/intermediate dosing in COVID-19 patients. This was a retrospective study conducted at a large COVID-19...

Humoral responses after inactivated COVID-19 vaccination in individuals with and withou...
https://doi.org/10.1002/jmv.28055
Journal of Medical Virology; Jia M, Wang X et. al.

Aug 10th, 2022 - We evaluated and compared humoral immune responses after inactivated COVID-19 vaccination among naïve individuals, asymptomatically infected individuals, and recovered patients with varying severity. In this multicenter, prospective cohort study, blood samples from 666 participants were collected before and after two doses of inactivated COVID-19 vaccination. Among 392 SARS-CoV-2-naïve individu...

Cervical ripening as an outpatient procedure in the pandemic - minimizing the inpatient...
https://doi.org/10.1515/jpm-2022-0196
Journal of Perinatal Medicine; Kummer J, Koenigbauer JT et. al.

Aug 10th, 2022 - With an increasing incidence of labor induction the socioeconomic costs are increasing and the burden on hospital capacities is rising. In addition, the worldwide SARS-CoV-2 pandemic asks for improvements in patient care during pregnancy and delivery while decreasing the patient-staff contact. Here, we are retrospectively analyzing and comparing a mechanical ripening device that is utilized as ...

Service Workers' Experience and Perceptions of Workplace Protective Measures During the...
https://doi.org/10.1177/21650799221101001
Workplace Health & Safety; Rosemberg MS, Adams M et. al.

Aug 10th, 2022 - The Coronavirus-2019 (COVID-19) pandemic presents a unique burden specifically for workers in service industries. However, limited research on service worker's experience during the onset of COVID-19 exists. We aimed to describe the experiences and concerns of service industry workers during the pandemic's onset. This is a mixed-method study. Participants were recruited through social media and...

Frequency of Abnormally Low Neuropsychological Scores in Post-COVID-19 Syndrome: the Ge...
https://doi.org/10.1093/arclin/acac068
Archives of Clinical Neuropsychology : the Official Journ... Voruz P, Jacot de Alcântara I et. al.

Aug 10th, 2022 - Several studies have reported poor long-term neuropsychological performances in patients following severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, but none has yet considered the effect of administering multiple intercorrelated neuropsychological tests and assessed the frequency of cognitive deficits in a normative population. Our aim was therefore to assess the presence...

Effect of Sodium Gluconate on Decreasing Elevated Nasal Calcium and Improving Olfactory...
https://doi.org/10.1177/19458924221120116
American Journal of Rhinology & Allergy; Abdelazim MH, Abdelazim AH

Aug 10th, 2022 - COVID-19 has been associated with temporary olfactory dysfunction in many infected patients. Calcium plays a great role in the olfaction process with negative feedback for the olfaction transmission. Many reports demonstrated calcium elevation in the nasal secretions with a negative effect on olfaction. Sodium gluconate is a water-soluble salt with a chemical structure that lends to act as a hi...

D-dimer Thresholds to Exclude Pulmonary Embolism among COVID-19 Patients in the Emergen...
https://doi.org/10.1177/10760296221117997
Clinical and Applied Thrombosis/hemostasis : Official Jou... Bledsoe JR, Knox D et. al.

Aug 10th, 2022 - To derive and validate a D-dimer cutoff for ruling out pulmonary embolism (PE) in COVID-19 patients presenting to the emergency department (ED). A retrospective cohort study was performed in an integrated healthcare system including 22 adult ED's between March 1, 2020, and January 31, 2021. Results were validated among patients enrolled in the RECOVER Registry, representing data from 154 ED's f...

Solid organ transplantation from COVID positive donors in the United States: Analysis o...
https://doi.org/10.1111/tid.13925
Transplant Infectious Disease : an Official Journal of Th... Dhand A, Okumura K et. al.

Aug 10th, 2022 - Significant uncertainties remain regarding the utilization of organs for solid organ transplantation (SOT) from donors with coronavirus disease 2019 (COVID-19). The aim of this study was to assess the trends in utilization of organs from donors with COVID-19 and their short-term outcomes. Deceased donors between March 2020 and December 2021 with a positive COVID nucleic acid test from respirato...

Delayed urologic cancer care in the COVID-19 pandemic: Patients' experiences.
https://doi.org/10.1111/ecc.13677
European Journal of Cancer Care; Glick H, Sarin A et. al.

Aug 10th, 2022 - To understand experiences of patients with genitourinary cancer who experienced delayed cancer care due to the COVID-19 pandemic. We conducted a mixed methods study with an explanatory sequential design. Qualitative findings are reported here. Patients with muscle invasive bladder, advanced prostate or kidney cancer were eligible. Participants were selected for interviews if they self-reported ...

Telemonitoring and protocolized case management for hypertensive community dwelling old...
https://doi.org/10.1097/HJH.0000000000003202
Journal of Hypertension; Lau D, Ringrose J et. al.

Aug 10th, 2022 - Home blood pressure (BP) telemonitoring combined with case management leads to BP reductions in individuals with hypertension. However, its benefits are less clear in older (age ≥ 65 years) adults. Twelve-month, open-label, randomized trial of community-dwelling older adults comparing the combination of home BP telemonitoring (HBPM) and pharmacist-led case management, vs. enhanced usual care wi...

Stay alert about coagulation parameters - implications of thrombosis treatment in COVID...
https://doi.org/10.1097/HJH.0000000000003264
Journal of Hypertension;

Aug 10th, 2022 - Stay alert about coagulation parameters - implications of thrombosis treatment in COVID-19: Erratum.|2022||

Implementing telepsychiatry in an early psychosis service during COVID-19: Experiences ...
https://doi.org/10.1111/eip.13342
Early Intervention in Psychiatry; Randall LA, Raisin C et. al.

Aug 10th, 2022 - In response to the COVID-19 pandemic, our early psychosis program rapidly transitioned to telepsychiatry. This study examined the change in health service utilization and experiences of young people and clinicians in response to the implementation of telepsychiatry. Mixed methodology and triangulation of evidence drawn from health service databases and survey data. Using a retrospective observa...

Severe Acute Respiratory Syndrome Coronavirus 2 Vaccine Boosters: An Influenza Vaccine ...
https://doi.org/10.1093/milmed/usac243
Military Medicine; Sayers DR

Aug 10th, 2022 - Changes to severe acute respiratory syndrome 2 (SARS-CoV-2) vaccine guidance since their initial authorization may lead to confusion and hesitancy. Suggested recommendations for an annual SARS-CoV-2 vaccine naturally draw comparisons with the influenza vaccine program. Considering viral and vaccine characteristics between these pathogens provides an important perspective that can help increase ...

Targeting Doublecortin-Like Kinase 1 (DCLK1)-Regulated SARS-CoV-2 Pathogenesis in COVID...
https://doi.org/10.1128/jvi.00967-22
Journal of Virology; Undi RB, Larabee JL et. al.

Aug 10th, 2022 - Host factors play critical roles in SARS-CoV-2 infection-associated pathology and the severity of COVID-19. In this study, we systematically analyzed the roles of SARS-CoV-2-induced host factors, doublecortin-like kinase 1 (DCLK1), and S100A9 in viral pathogenesis. In autopsied subjects with COVID-19 and pre-existing chronic liver disease, we observed high levels of DCLK1 and S100A9 expression ...

Severe Vitamin D Deficiency in Youth with Autism Spectrum Disorder During the COVID-19 ...
https://doi.org/10.1097/DBP.0000000000001096
Journal of Developmental and Behavioral Pediatrics : JDBP; Ganta A, S Pillai S et. al.

Aug 10th, 2022 - Decrease in sunlight exposure during periods of social distancing during the COVID-19 pandemic increased the risk of severe manifestations of vitamin D deficiency (VDD) in a particular "high-risk" population. Our objective was to highlight the importance of vitamin D screening in youth with autism spectrum disorder (ASD) and restrictive eating. We describe 3 adolescent male patients with ASD wh...

Habilitative Teletherapy for Children with Autism Spectrum Disorder: A Survey of Parents.
https://doi.org/10.1097/DBP.0000000000001106
Journal of Developmental and Behavioral Pediatrics : JDBP; Choi KR, Becerra-Culqui TA et. al.

Aug 10th, 2022 - The purpose of this study was to investigate whether service losses during the coronavirus disease 2019 (COVID-19) pandemic were associated with worsened parent mental health or child behavioral health among families of children with autism spectrum disorder and to identify factors associated with favorable parent appraisals of habilitative teletherapy (applied behavior analysis; speech, occupa...

Reduced HIV Testing and Diagnoses During COVID-19 Pandemic.
https://doi.org/10.1001/jama.2022.12790
JAMA Kuehn BM

Aug 10th, 2022 - Reduced HIV Testing and Diagnoses During COVID-19 Pandemic.|2022|Kuehn BM,|

Selective serotonin reuptake inhibitor (SSRI) antidepressants reduce COVID-19 infection...
https://doi.org/10.1007/s00228-022-03372-5
European Journal of Clinical Pharmacology; Foletto VS, da Rosa TF et. al.

Aug 10th, 2022 - The absence of specific treatments for COVID-19 leads to an intense global effort in the search for new therapeutic interventions and better clinical outcomes for patients. This review aimed to present a selection of accepted studies that reported the activity of antidepressant drugs belonging to the selective serotonin receptor inhibitor (SSRI) class for treating the novel coronavirus. A searc...

Home urinary tract infection testing: patient experience and satisfaction with polymera...
https://doi.org/10.1007/s00192-022-05309-z
International Urogynecology Journal; Melnyk AI, Toal C et. al.

Aug 10th, 2022 - We sought to evaluate patient satisfaction with a novel multiplex PCR UTI home collection kit for symptomatic UTI in a urogynecologic population. We secondarily sought to characterize reported uropathogens and resistance profiles of uropathogens in this population. We hypothesized that patients would be satisfied. This was a cross-sectional study of women who were surveyed later about their exp...

Acute kidney injury following multisystem inflammatory syndrome associated with SARS-Co...
https://doi.org/10.1007/s00467-022-05701-3
Pediatric Nephrology (Berlin, Germany); Tripathi AK, Pilania RK et. al.

Aug 10th, 2022 - Multisystem inflammatory syndrome (MIS-C) is a rare paediatric hyper-inflammatory disorder that occurs following SARS-CoV-2 infection. Acute kidney injury (AKI) occurs in approximately one-quarter to one-third of the patients with MIS-C and is associated with poor prognosis in critically ill children. This systematic review is aimed to evaluate the incidence of AKI, mortality, and the need for ...

Male reproductive health after 3 months from SARS-CoV-2 infection: a multicentric study.
https://doi.org/10.1007/s40618-022-01887-3
Journal of Endocrinological Investigation; Paoli D, Pallotti F et. al.

Aug 10th, 2022 - While SARS-CoV-2 infection appears not to be clinically evident in the testes, indirect inflammatory effects and fever may impair testicular function. To date, few long-term data of semen parameters impairment after recovery and comprehensive andrological evaluation of recovered patients has been published. The purpose of this study was to investigate whether SARS-CoV-2 infection affect male re...

Influenza Clinical Presentation
http://emedicine.medscape.com/article/219557-clinical

Aug 10th, 2022 - History The presentation of influenza virus infection varies; however, it usually includes many of the symptoms described below. Patients with influenza who have preexisting immunity or who have received vaccine may have milder symptoms. Onset of illness can occur suddenly over the course of a day, or it can progress more slowly over the course of several days. Typical signs and symptoms includ...

Influenza Clinical Presentation
https://emedicine.medscape.com/article/219557-clinical

Aug 10th, 2022 - History The presentation of influenza virus infection varies; however, it usually includes many of the symptoms described below. Patients with influenza who have preexisting immunity or who have received vaccine may have milder symptoms. Onset of illness can occur suddenly over the course of a day, or it can progress more slowly over the course of several days. Typical signs and symptoms includ...

Children and COVID: Severe illness rising as vaccination effort stalls
https://www.mdedge.com/pediatrics/article/256935/covid-19-updates/children-and-covid-severe-illness-rising-vaccination
Richard Franki

Aug 9th, 2022 - New cases of COVID-19 rose among children for the fourth consecutive week, but the size of the increase declined for the second consecutive week, based on data from the American Academy of Pediatrics and the Children’s Hospital Association. After new child cases jumped by 22% during the week of July 15-21, the two successive weeks have produced increases of 3.

Differences in Underrepresented in Medicine Applicant Backgrounds and Outcomes in the 2020-2021 Dermatology Residency Match
https://www.mdedge.com/dermatology/article/256914/diversity-medicine/differences-underrepresented-medicine-applicant
Fatuma-Ayaan Rinderknecht, MS, Caitlin M. Brumfiel, MD et. al.

Aug 9th, 2022 - Dermatology is one of the least diverse medical specialties with only 3% of dermatologists being Black and 4% Latinx. 1 Leading dermatology organizations have called for specialty-wide efforts to improve diversity, with a particular focus on the resident selection process.

FDA Roundup: August 9, 2022 | FDA
https://www.fda.gov/news-events/press-announcements/fda-roundup-august-9-2022

Aug 9th, 2022 - For Immediate Release: August 09, 2022 Today, the U.S. Food and Drug Administration is providing an at-a-glance summary of news from around the agency: Today, the FDA’s Office of Global Policy and Strategy published “How a European Data Law is Impacting FDA,” which looks at how the European Union’s General Data Protection Regulation may be impacting the FDA’s public health activities. So far, t...

Impact of SARS-CoV-2 Omicron on Rapid Antigen Testing Developed for Early-Pandemic SARS-CoV-2 Variants
https://journals.asm.org/doi/10.1128/spectrum.02006-22
Microbiology Spectrum; Leuzinger K, .

Aug 9th, 2022 - Rapid antigen tests (RATs) are widely used for point-of-care or self-testing to identify SARS-CoV-2 (SCoV2), but currently circulating Omicron variants may impair detection. In this study, we prospectively evaluated the Roche-SARS-CoV-2-Antigen and Acon-FlowFlex-SARS-CoV-2-Antigen in 150 consecutively collected nasopharyngeal patient swabs (50 SCoV2 RNA undetectable; 100 SCoV2 Omicron BA.1).

Medical students' perspectives on how COVID-19 has impacted their otolaryngology educat...
https://doi.org/10.1177/01455613221115107
Ear, Nose, & Throat Journal; Habib AM, Yu V et. al.

Aug 9th, 2022 - To evaluate how medical students perceive COVID-19 has impacted various otolaryngology educational experiences and appreciate useful adaptations/resources that can be implemented moving forward. We circulated a web-based questionnaire among pre-clinical/clinical medical students. Participants were asked to rate their experiences in the realms of research, clinical exposure, faculty interaction,...

Correlation Analysis of Positive Therapy Based on High Content Image Analysis Technolog...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9297126
Contrast Media & Molecular Imaging; Zheng T, Lin J et. al.

Aug 9th, 2022 - To investigate the correlation between posttraumatic stress disorder (PTSD) and the incidence of anxiety, depression, and mental disorders in patients with novel coronavirus pneumonia. Novel coronavirus pneumonia patients in Wuhan from 2020 to April were selected for treatment from hospitals and isolation wards from 1 to April. 70 rehabilitated patients were randomly divided into the control gr...

SARS-CoV-2-Specific T Cell Immunity in HIV-Associated Kaposi Sarcoma Patients in Zambia.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9352483
Journal of Immunology Research; Ngalamika O, Mukasine MC et. al.

Aug 9th, 2022 - Severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2) virus is the cause of coronavirus disease 2019 (COVID-19). It has caused millions of infections and deaths globally over a 2-year period. Some populations including those living with HIV and/or cancer are reported to be at a higher risk of infection and severe disease. HIV infection leads to a depletion of CD4+ T cells which impa...

SARS-CoV-2 Spike Protein Vaccine-Induced Immune Imprinting Reduces Nucleocapsid Protein...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9355782
Journal of Immunology Research; Delgado JF, Vidal-Pla M et. al.

Aug 9th, 2022 - Immune imprinting or original antigenic sin (OAS) is the process by which the humoral memory response to an antigen can inhibit the response to new epitopes of that antigen originating from a second encounter with the pathogen. Given the situation of the COVID-19 pandemic, multiple vaccines have been developed against SARS-CoV-2 infection. These vaccines are directed to the spike protein (S pro...

A Cross-Sectional Study of Depression, Anxiety, and Insomnia Symptoms in People in Quar...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9346268
International Journal of Public Health; Lin C, Fu X

Aug 9th, 2022 - Objective: To investigate the status and influential factors of depression, anxiety, and insomnia among people in quarantine during COVID-19. Methods: Data was collected from August 2020 to November 2021 through an online survey of 1,360 people in a quarantined hotel. The Patient Health Questionnaire-9 (PHQ-9), Generalized Anxiety Disorder-7 (GAD-7), and Insomnia Severity Index (ISI) were used ...

Interstitial lung disease following coronavirus disease 2019.
https://doi.org/10.1097/MCP.0000000000000900
Current Opinion in Pulmonary Medicine; Vasarmidi E, Ghanem M et. al.

Aug 9th, 2022 - The aim of this review was to summarize the recent data concerning interstitial lung disease after COVID-19, a field where knowledge is evolving very quickly. It has been found that a proportion of patients displayed fibrotic-like pattern on chest computed tomography shortly after COVID-19 pneumonia. Those lesions can potentially represent precursors of fibrosis, although most of them will reso...

The impact of the first COVID-19 lockdown on presentations with depressive symptoms in ...
https://doi.org/10.1017/S104161022200062X
International Psychogeriatrics; Velayudhan L, Cheung WY et. al.

Aug 9th, 2022 - The impact of the first COVID-19 lockdown on presentations with depressive symptoms in older people - an electronic health records study.|2022|Velayudhan L,Cheung WY,Perera G,Stewart R,Mueller C,|

The Rapid Uptake of Digital Technologies at Domestic Violence and Sexual Assault Organi...
https://doi.org/10.1177/10778012221094066
Violence Against Women; Storer HL, Nyerges EX

Aug 9th, 2022 - Emerging evidence suggests that the COVID-19 pandemic disproportionately impacted survivors of domestic violence and sexual assault (DV/SA). This research note explores DV/SA service providers' (n = 20) perceptions of how their organizations responded to the pandemic. Results of a thematic content analysis indicated that survivors were adversely affected by sheltering with abusive partners and ...

Could red cell distribution width be used for predicting cardiac injury in neonates wit...
https://doi.org/10.1002/jmv.28050
Journal of Medical Virology; Elbayiyev S, Şimşek GK et. al.

Aug 9th, 2022 - Coronavirus disease 2019 (COVID-19) can affect people of all age groups and it can occasionally cause life-threatening clinical illness in immunologically immature population, especially in newborns. High red cell distribution width (RDW) values were used as early prognostic biomarker of some neonatal diseases. We aimed to determine the prognostic value of red cell distribution width in severe ...

Evaluating the Role of Pharmacy Technician-Administered Vaccines.
https://doi.org/10.1177/08971900221117893
Journal of Pharmacy Practice; Fuschetto KS, Amin KA et. al.

Aug 9th, 2022 - Before the COVID-19 pandemic, most states limited administration of vaccines to trained pharmacists and pharmacy interns. In October 2020 due to the public health emergency, the Federal Public Readiness and Emergency Preparedness Act (PREP Act) authorized qualified pharmacy technicians to administer vaccines nationally. Currently available research on the perception of pharmacy technician-admin...

Current Status of Burnout in Canadian Radiology.
https://doi.org/10.1177/08465371221117282
Canadian Association of Radiologists Journal = Journal L'... Cao DJ, Hurrell C et. al.

Aug 9th, 2022 - Burnout is a healthcare concern affecting physicians around the world. Physicians experiencing burnout tend to display signs of emotional exhaustion, depersonalization, and low personal accomplishment. Ongoing burnout trends have posed numerous challenges to Canadian physicians, notwithstanding the added complexity of the COVID-19 pandemic's impact in recent years. In particular, Canadian radio...

Outcomes following peritoneal dialysis for COVID-19-induced AKI: A literature review.
https://doi.org/10.1177/08968608221115000
Peritoneal Dialysis International : Journal of the Intern... Atlani MK, Pilania RK et. al.

Aug 9th, 2022 - Acute kidney injury (AKI) has been shown to be associated with significant morbidity and mortality in patients with severe COVID-19 disease. Due to increasing number of cases in pandemic, there is a significant shortage of medical facilities and equipment in relation to patient load. In low resource settings where access to intermittent haemodialysis (HD) or continuous kidney replacement therap...

Keys to well-being in older adults during the COVID-19 pandemic: personality, coping an...
https://doi.org/10.1080/17482631.2022.2110669
International Journal of Qualitative Studies on Health An... Mau M, Fabricius AM et. al.

Aug 9th, 2022 - During the COVID-19 pandemic, older adults were portrayed as an at-risk group. While this may have been true in some respects, empirical studies on mental health, including well-being were conflicting. Some studies found that older adults demonstrated a notable emotional resilience against the impacts of the pandemic. In this study, we qualitatively examine how older adults understand well-bein...

Facial Nerve Paralysis and COVID-19: A Systematic Review.
https://doi.org/10.1002/lary.30333
The Laryngoscope; Namavarian A, Eid A et. al.

Aug 9th, 2022 - Several cases of facial nerve paralysis (FNP) post-COVID-19 infection have been reported with varying presentations and management. This study aims to identify FNP clinical characteristics and recovery outcomes among patients acutely infected with COVID-19. We hypothesize that FNP is a potentially unique sequalae associated with COVID-19 infections. A systematic review of PubMed-Medline, OVID E...

The impact of stay-at-home regulations on adolescents' feelings of loneliness and inter...
https://doi.org/10.1002/jad.12084
Journal of Adolescence; Barbieri M, Mercado E

Aug 9th, 2022 - The COVID-19 pandemic disrupted the daily social lives of adolescents by severely limiting social interactions which likely heightened levels of loneliness and a variety of internalizing symptoms. However, little is known about how social distancing adherence and subsequent stress caused by the novel social regulations impact adolescents' feelings of loneliness, and later mental health difficul...

Global Pediatric Surgery in the Era of COVID-19.
https://doi.org/10.3928/19382359-20220606-06
Pediatric Annals; Raiji MT, Linden AF

Aug 9th, 2022 - There is a tremendous unmet need regarding the surgical care of children in low- and middle-income countries. The rapid spread of coronavirus disease 2019 (COVID-19), and the resultant redistribution of health care resources required to combat it, has created even more unique difficulties in the provision of safe, timely, and affordable surgical care of children globally. The downstream effects...