Emerging Infectious Diseases;
Oct 31st, 2020 - To assess the role of in-flight transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), we investigated a cluster of cases among passengers on a 10-hour commercial flight.
Emerging Infectious Diseases;
Oct 31st, 2020 - In 2019, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged in China, ultimately causing the coronavirus disease (COVID-19) pandemic. Many persons with SARS-CoV-2 infection have since flown into and out of COVID-19–affected areas. Some countries quarantine arriving passengers. Airports are also screening passenger body temperatures before boarding and after arrival. Recent inv...
BMJ (Clinical Research Ed.); Car J, Koh GC et. al.
Oct 21st, 2020 - Video consultations in primary and specialist care during the covid-19 pandemic and beyond.|2020|Car J,Koh GC,Foong PS,Wang CJ,|
BMJ (Clinical Research Ed.); Tanne JH
Oct 21st, 2020 - Covid-19: Fauci awarded for "unprecedented public service" while Trump fires more insults.|2020|Tanne JH,|
BMJ (Clinical Research Ed.); Sperrin M, McMillan B
Oct 21st, 2020 - Prediction models for covid-19 outcomes.|2020|Sperrin M,McMillan B,|
BMJ (Clinical Research Ed.); Clift AK, Coupland CAC et. al.
Oct 21st, 2020 - To derive and validate a risk prediction algorithm to estimate hospital admission and mortality outcomes from coronavirus disease 2019 (covid-19) in adults. Population based cohort study. QResearch database, comprising 1205 general practices in England with linkage to covid-19 test results, Hospital Episode Statistics, and death registry data. 6.08 million adults aged 19-100 years were included...
BMJ Open; Wang Y, Li Y et. al.
Oct 21st, 2020 - The COVID-19 outbreak has caused enormous strain on healthcare systems, and healthcare trainees, which comprise the future healthcare workforce, may be a vulnerable group. It is essential to assess the psychological distress experienced by healthcare trainees during the COVID-19 outbreak. A cross-sectional study with 4184 healthcare trainees at Sichuan University in China was implemented during...
BMJ Open; Palinkas LA, Whiteside L et. al.
Oct 21st, 2020 - Assess the impacts of the COVID-19 pandemic on service delivery by frontline healthcare providers in acute care medical and emergency department settings and identify strategies used to cope with pandemic-related physical and mental health demands. Rapid clinical ethnography of patient-provider encounters during an initial pandemic 'surge' conducted by a team of clinician-researchers using a st...
https://doi.org/10.1073/pnas.2018030117 10.1056/NEJMoa2020283 10.1056/NEJMoa2007764.0028-4793 10.1056/nejmoa2021436
Proceedings of the National Academy of Sciences of the United States of America; Wu M, Chen Y et. al.
Oct 21st, 2020 - Coronavirus disease 2019 (COVID-19), the global pandemic caused by SARS-CoV-2, has resulted thus far in greater than 933,000 deaths worldwide; yet disease pathogenesis remains unclear. Clinical and immunological features of patients with COVID-19 have highlighted a potential role for changes in immune activity in regulating disease severity. However, little is known about the responses in human...
Proceedings of the National Academy of Sciences of the United States of America; Polyakova M, Kocks G et. al.
Oct 21st, 2020 - The economic and mortality impacts of the COVID-19 pandemic have been widely discussed, but there is limited evidence on their relationship across demographic and geographic groups. We use publicly available monthly data from January 2011 through April 2020 on all-cause death counts from the Centers for Disease Control and Prevention and employment from the Current Population Survey to estimate...
Sexually Transmitted Infections; Michielsen K, Larrson EC et. al.
Oct 21st, 2020 - COVID-19 may have a profound impact on sexual health, reproductive health and social life across the world. Shelter in place regulations that have extended across the globe may influence condomless sex, exacerbate intimate partner violence and reduce access to essential reproductive health services. Population representative research is challenging during shelter in place, leaving major gaps in...
Sexually Transmitted Infections; Chia CC, Chao CM et. al.
Oct 21st, 2020 - Diagnoses of syphilis and HIV infection during the COVID-19 pandemic in Taiwan.|2020|Chia CC,Chao CM,Lai CC,|
Gut Ungaro RC, Brenner EJ et. al.
Oct 21st, 2020 - We sought to evaluate COVID-19 clinical course in patients with IBD treated with different medication classes and combinations. Surveillance Epidemiology of Coronavirus Under Research Exclusion for Inflammatory Bowel Disease (SECURE-IBD) is a large, international registry created to monitor outcomes of IBD patients with confirmed COVID-19. We used multivariable regression with a generalised est...
Molecular Pharmacology; Hammoud S, Wehbe Z et. al.
Oct 21st, 2020 - ACE2 has emerged as a double agent in the COVID-19 ordeal being physiologically protective yet conducive of viral infection. The identification of ACE2 in as many as 72 tissues suggests that extra-pulmonary invasion and damage is likely, which indeed has already been demonstrated by cardiovascular and gastro-intestinal symptoms. On the other hand, identifying ACE2 dysregulation in patients with...
Journal of Neurointerventional Surgery; Bechstein M, Elsheikh S et. al.
Oct 21st, 2020 - This is a report of the first three cases of endovascular aneurysm treatment that were proctored by a remote interventionalist using a novel high-resolution low-latency streaming technology. The proctor was located in a neurovascular centre and supported the treating interventional teams in two distant cities (up to 800 km/500 miles apart). All aneurysms were treated using the Woven EndoBridge ...
Nature Communications; Lyngbakken MN, Berdal JE et. al.
Oct 21st, 2020 - Here, we randomized 53 patients hospitalized with coronavirus disease 2019 (COVID-19) to hydroxychloroquine therapy (at a dose of 400 mg twice daily for seven days) in addition to standard care or standard care alone (ClinicalTrials.gov Identifier, NCT04316377). All severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) positive patients 18 years of age or older were eligible for study in...
Nature Subbarao K
Oct 21st, 2020 - COVID-19 vaccines: time to talk about the uncertainties.|2020|Subbarao K,|
Nature Mundt AP
Oct 21st, 2020 - Question hubris in nations' COVID-19 responses.|2020|Mundt AP,|
Nature Callaway E
Oct 21st, 2020 - Dozens to be deliberately infected with coronavirus in UK 'human challenge' trials.|2020|Callaway E,|
Nature Chemical Biology; Bracken CJ, Lim SA et. al.
Oct 21st, 2020 - Neutralizing agents against SARS-CoV-2 are urgently needed for the treatment and prophylaxis of COVID-19. Here, we present a strategy to rapidly identify and assemble synthetic human variable heavy (VH) domains toward neutralizing epitopes. We constructed a VH-phage library and targeted the angiotensin-converting enzyme 2 (ACE2) binding interface of the SARS-CoV-2 Spike receptor-binding domain ...
Nature Medicine; Lazarus JV, Ratzan SC et. al.
Oct 21st, 2020 - Several coronavirus disease 2019 (COVID-19) vaccines are currently in human trials. In June 2020, we surveyed 13,426 people in 19 countries to determine potential acceptance rates and factors influencing acceptance of a COVID-19 vaccine. Of these, 71.5% of participants reported that they would be very or somewhat likely to take a COVID-19 vaccine, and 61.4% reported that they would accept their...
Canadian Respiratory Journal; Ayele Mega T, Feyissa TM et. al.
Oct 21st, 2020 - The pandemic of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) resulted in an unprecedented public health challenge worldwide. Despite urgent and extensive global efforts, the existing evidence is inconclusive regarding the medications used for the treatment of COVID-19. To generate an up-to-date evidence for the clinical safety and ef...
Journal of Pediatric Psychology; C Fong V, Iarocci G
Oct 21st, 2020 - A systematic review of mental health outcomes and needs of children and families during past pandemics was conducted based on the PRISMA protocol. The objectives were to evaluate the quality of existing studies on this topic, determine what is known about mental health outcomes and needs of children and families, and provide recommendations for how COVID-19 policies can best support children an...
The Journal of Infectious Diseases; Zhu J, Wu C et. al.
Oct 21st, 2020 - It is critical to identify potential causal targets for SARS-coronavirus 2, which may guide drug repurposing options. We assessed the associations between genetically predicted protein levels and COVID-19 severity. Leveraging data from The COVID-19 host genetics initiative comparing 6,492 hospitalized COVID-19 patients and 1,012,809 controls, we identified 18 proteins with genetically predicted...
Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology; Malek H, Maghsudi M et. al.
Oct 21st, 2020 - Extra-cardiac multifocal lung uptake of 99mTc-sestamibi in myocardial perfusion imaging: An asymptomatic case with coronavirus infection features.|2020|Malek H,Maghsudi M,Yaghoobi N,|
Drugs & Aging; Casucci G, Acanfora D et. al.
Oct 21st, 2020 - This paper presents a brief overview of the complex interaction between age, hypertension, the renin-angiotensin-aldosterone system (RAAS), inflammation, and severe acute respiratory syndrome coronavirus 2 (SARS-CoV2) infection. Coronavirus disease 2019 (COVID-19) is more frequent and more severe in comorbid elderly patients, especially those with hypertension, diabetes, obesity, or cardiovascu...
Artificial Organs; Melegari G, Bertellini E et. al.
Oct 21st, 2020 - The cytokine storm has been frequently reported to occur in patients with severe coronavirus disease 2019 (COVID-19). Data from the literature suggest that elevated levels of inflammatory mediators, such as interleukin (IL)-6, IL-8, and tumor necrosis factor, indicate a severe course or the fatality of the disease. Several therapeutic options have been employed to treat critically ill patients,...
European Journal of Immunology; Figueiredo-Campos P, Blankenhaus B et. al.
Oct 21st, 2020 - SARS-CoV-2 has emerged as a human pathogen, causing clinical signs, from fever to pneumonia - COVID-19 - but may remain mild or asymptomatic. To understand the continuing spread of the virus, to detect those who are and were infected, and to follow the immune response longitudinally, reliable and robust assays for SARS-CoV-2 detection and immunological monitoring are needed. We quantified immun...
International Journal of Dermatology References; Weingarten M, Abittan B et. al.
Oct 21st, 2020 - Treatment of COVID-19 induced chilblains with topical nitroglycerin.|2020|Weingarten M,Abittan B,Rivera-Oyola R,Abittan AI,Weingarten M,|
International Journal of Dermatology References; Altayeb A, Cordaro A et. al.
Oct 21st, 2020 - Two cases of skin manifestations prior to the onset of COVID-19 respiratory symptoms.|2020|Altayeb A,Cordaro A,Caesar J,Vyas J,Ingram J,|
Journal of Surgical Oncology REFERENCES; Vissio E, Falco EC et. al.
Oct 21st, 2020 - Italy was severely affected by the severe acute respiratory syndrome coronavirus 2 pandemic. Our Institution, Piedmont's largest tertiary referral center, was designated as a non-COVID-19 hospital and activities were reorganized to prioritize critical services like oncological care. The aim of this study was to investigate the efficacy in preserving the oncological surgical practice at our Inst...
Medicinal Research Reviews REFERENCES; Rufino AT, Costa VM et. al.
Oct 21st, 2020 - Obesity is a global health problem that affects all age groups in both developing and developed countries. In recent years, the prevalence of overweight and obesity has reached pandemic levels, resulting in a dramatic increase in the incidence of various comorbidities, such as cardiovascular diseases, type 2 diabetes, and cancer, consequently leading to massive health and socioeconomic burdens....
Journal of Cardiac Surgery REFERENCES; Rooijakkers MJP, Li WWL et. al.
Oct 21st, 2020 - The coronavirus disease 2019 (COVID-19) pandemic has put an enormous strain on healthcare systems and intensive care unit (ICU) capacity, leading to suspension of most elective procedures, including transcatheter aortic valve replacement (TAVR). However, deferment of TAVR is associated with significant wait-time mortality in patients with severe aortic valve stenosis. Conversely, there is curre...
American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons; Coiffard B, Lepper PM et. al.
Oct 21st, 2020 - It is unknown if solid organ transplant recipients are at higher risk for severe COVID-19. The management of a lung transplantation (LTx) program and the therapeutic strategies to adapt the immunosuppressive regimen and antiviral measures is a major issue in the COVID-19 era, but little is known about worldwide practice. We sent out to 180 LTx centers worldwide in June 2020 a survey with 63 que...
The Journal of Clinical Psychiatry; Chew QH, Wei KC et. al.
Oct 21st, 2020 - In light of the current evolving coronavirus disease 2019 (COVID-19) pandemic, and the need to learn from past infectious disease outbreaks to provide better psychological support for our frontline health care workers (HCW), we conducted a rapid review of extant studies that have reported on both psychological and coping responses in HCW during recent outbreaks. We performed a systematic search...
The Annals of Otology, Rhinology, and Laryngology; Pagedar NA, Seaman AT
Oct 21st, 2020 - Rebuilding survivorship care during Covid-19.|2020|Pagedar NA,Seaman AT,|
Infection Control and Hospital Epidemiology; Ong SWX, Lee PH et. al.
Oct 21st, 2020 - The risk of environmental contamination by SARS-CoV-2 in the intensive care unit (ICU) is unclear. We aimed to evaluate the extent of environmental contamination in the ICU and correlate this with patient and disease factors, including the impact of different ventilatory modalities. Observational study where surface environmental samples collected from ICU patient rooms and common areas were te...
Prehospital and Disaster Medicine; Aljahany M, Alassaf W et. al.
Oct 21st, 2020 - During the world-wide coronavirus disease 2019 (COVID-19) outbreak, there is an urgent need to rapidly increase the readiness of hospitals. Emergency departments (EDs) are at high risk of facing unusual situations and need to prepare extensively in order to minimize risks to health care providers (HCPs) and patients. In situ simulation is a well-known method used in training to detect system ga...
The British Journal of Psychiatry : the Journal of Mental Science; O'Connor RC, Wetherall K et. al.
Oct 21st, 2020 - Mental health and wellbeing during the COVID-19 pandemic: longitudinal analyses of adults in the UK COVID-19 Mental Health & Wellbeing study.|2020|O'Connor RC,Wetherall K,Cleare S,McClelland H,Melson AJ,|
CNS Spectrums; Ibrahim W
Oct 21st, 2020 - Neurological Manifestations in Coronavirus Disease 2019 (COVID-19) Patients: A Systematic Review of Literature.|2020|Ibrahim W,|
CNS Spectrums; Jalal B, Chamberlain SR et. al.
Oct 21st, 2020 - Obsessive-compulsive disorder-contamination fears, features and treatment: Novel smartphone therapies in light of global mental health and pandemics (COVID-19).|2020|Jalal B,Chamberlain SR,Robbins TW,Sahakian BJ,|
Disaster Medicine and Public Health Preparedness; Abobaker A, Oluwalana I
Oct 21st, 2020 - The impact of COVID-19 pandemic on post-operative follow-up after total hip and knee joints replacement.|2020|Abobaker A,Oluwalana I,|
The Journal of Laryngology and Otology; Murdin L, Saman Y et. al.
Oct 21st, 2020 - The remote neuro-otology assessment - managing dizziness in the coronavirus disease 2019 era.|2020|Murdin L,Saman Y,Rea P,|
The Journal of Laryngology and Otology; Shenton C, Aucott W
Oct 21st, 2020 - How I do it: a simulator of the ear for developing otomicroscopy skills during the coronavirus disease 2019 pandemic.|2020|Shenton C,Aucott W,|
Advances in Genetics; Steele EJ
Oct 21st, 2020 - This current volume is, in many ways, a 2020 update to the important 1999-2000 compendium by Sir Fred Hoyle and Professor N. Chandra Wickramasinghe's "Astronomical Origins of life: Steps towards Panspermia." The emerging new paradigm of biology that connects life on Earth with the wider cosmos is covered in considerable depth showing that terrestrial biological evolution is best understood as a...
Advances in Genetics; Wickramasinghe NC
Oct 21st, 2020 - WHO's pronouncement of the 2019 novel coronavirus outbreak as a pandemic disease came months after we published a warning that the present deepest minimum of the sunspot cycle would be likely to facilitate the onset of a viral pandemic. During a deep sunspot minimum (deepest in 100 years) such as we are now witnessing, two space related phenomena could have an effect on the disposition of viral...
Advances in Genetics; Steele EJ, Gorczynski RM et. al.
Oct 21st, 2020 - The origins and global spread of two recent, yet quite different, pandemic diseases is discussed and reviewed in depth: Candida auris, a eukaryotic fungal disease, and COVID-19 (SARS-CoV-2), a positive strand RNA viral respiratory disease. Both these diseases display highly distinctive patterns of sudden emergence and global spread, which are not easy to understand by conventional epidemiologic...
Travel Medicine and Infectious Disease; Maleki M, Mahmoudi MR et. al.
Oct 21st, 2020 - Coronaviruses are enveloped RNA viruses from the Coronaviridae family affecting neurological, gastrointestinal, hepatic and respiratory systems. In late 2019 a new member of this family belonging to the Betacoronavirus genera (referred to as COVID-19) originated and spread quickly across the world calling for strict containment plans and policies. In most countries in the world, the outbreak of...
Current Problems in Cardiology; Mahmoud SED, Etriby SE et. al.
Oct 21st, 2020 - The World Health Organization (WHO) announced that the novel coronavirus pneumonia pandemic caused by SARS-CoV-2 was classified as a public health emergency of international concern on January 30, 2020 Egypt's health ministry had announced the first case in the country at Cairo International Airport involving a Chinese national on 14 February 2020. Case decisions in the cath labs should be indi...
Current Problems in Cardiology; Elbaum L, Rashed E et. al.
Oct 21st, 2020 - During the coronavirus disease 2019 (COVID-19) pandemic, strained acute care resources, the potential for rapid clinical decompensation, and concerns about staff safety has prompted a conservative management approach for acute coronary syndrome patients. We present our experience of COVID-19 patients at Elmhurst Hospital Center presenting with ST-Elevation Myocardial Infarction and compared out...
Vaccine Safavi A, Kefayat A et. al.
Oct 21st, 2020 - SARS-CoV-2 causes a severe respiratory disease called COVID-19. Currently, global health is facing its devastating outbreak. However, there is no vaccine available against this virus up to now. In this study, a novel multi-epitope vaccine against SARS-CoV-2 was designed to provoke both innate and adaptive immune responses. The immunodominant regions of six non-structural proteins (nsp7, nsp8, n...
Trends in Endocrinology and Metabolism: TEM; Brandi ML, Giustina A
Oct 21st, 2020 - The recent coronavirus disease 2019 (COVID-19) pandemic showed a different severity in the disease between males and females. Men have been becoming severely ill at a higher rate than women. These data along with an age-dependent disease susceptibility and mortality in the elderly suggest that sex hormones are the main factors in determining the clinical course of the infection. The differences...
Ultrasound in Medicine & Biology; Bennett D, De Vita E et. al.
Oct 21st, 2020 - Ultrasound imaging of the lung (LUS) and associated tissues has demonstrated clinical utility in coronavirus disease 2019 (COVID-19) patients. The aim of the present study was to evaluate the possibilities of a portable pocket-sized ultrasound scanner in the evaluation of lung involvement in patients with COVID-19 pneumonia. We conducted 437 paired readings in 34 LUS evaluations of hospitalized...
Brain & Development; Bektaş G, Akçay N et. al.
Oct 21st, 2020 - Reversible splenial lesion syndrome (RESLES) is characterized by a temporary lesion in the splenium of the corpus callosum, emerging related to encephalitis, seizures, antiepileptic drug withdrawal, or metabolic disturbances. Among RESLES, mild encephalitis/encephalopathy with reversible splenial lesion (MERS) has been defined as a distinct clinicoradiologic syndrome associated with viral infec...
Cytotherapy Iglesias-Lopez C
Oct 21st, 2020 - Temporary derogation from European environmental legislation for clinical trials of genetically modified organisms for coronavirus disease 2019.|2020|Iglesias-Lopez C,|
Disability and Health Journal; Meleo-Erwin Z, Kollia B et. al.
Oct 21st, 2020 - The COVID-19 pandemic necessitated a rapid shift to remote instruction. This may have caused particular challenges for students with disabilities. We aimed to describe the availability of remote instruction and counseling resources on the disability/accessibility websites of colleges and universities in the greater New York City area. At the time this study was conducted, this region was the gl...
Journal of Primary Care & Community Health; Techasatian L, Lebsing S et. al.
Oct 21st, 2020 - The study aimed to explore the prevalence and possible risk factors to prevent the face mask related adverse skin reactions during the ongoing COVID-19 after a recommendation of face mask wearing for public use in Thailand. The prevalence of face mask related adverse skin reactions was 454 cases (54.5%), of which acne was the most frequent (399; 39.9%), followed by rashes on the face (154; 18.4...
Journal of Primary Care & Community Health; Dominguez LW, Willis JS
Oct 21st, 2020 - Hospitals and health systems suffer an over-reliance on elective surgeries to remain profitable. As a result, systems report record losses, while demand for emergency room, hospital, and intensive care beds have surged. Studies have admitted that many surgeries are unnecessary, and physician leaders admit that profit plays a role in driving such needless cost and risk. Most diseases are better ...
Health Care for Women International; Reizer A, Koslowsky M et. al.
Oct 21st, 2020 - After the COVID-19 virus was officially declared a pandemic on March 11, 2020, the Israeli government adopted lockdown restrictions to limit its spread. The purpose of the present article is to examine the impact of this disturbing environment on Israeli women. Specifically, we examined whether fear of the virus would impact the women's distress symptoms, self-rated health (SRH), and marital sa...
Emerging Infectious Diseases; Marr KA, Platt A et. al.
Oct 21st, 2020 - Aspergillosis complicating severe influenza infection has been increasingly detected worldwide. Recently, coronavirus disease-associated pulmonary aspergillosis (CAPA) has been detected through rapid reports, primarily from centers in Europe. We provide a case series of CAPA, adding 20 cases to the literature, with review of pathophysiology, diagnosis, and outcomes. The syndromes of pulmonary a...
JAMA Psychiatry; Carlo AD, Barnett BS et. al.
Oct 21st, 2020 - Harnessing Collaborative Care to Meet Mental Health Demands in the Era of COVID-19.|2020|Carlo AD,Barnett BS,Unützer J,|
Clinical Chemistry; Suhandynata RT, Hoffman MA et. al.
Oct 21st, 2020 - It is unknown whether a positive serology result correlates with protective immunity against SARS-CoV-2. There are also concerns regarding the low positive predictive value of SARS-CoV-2 serology tests, especially when testing populations with low disease prevalence. A neutralization assay was validated in a set of PCR confirmed positive specimens and in a negative cohort. In addition, 9,530 sp...
European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery; Caraffa R, Bagozzi L et. al.
Oct 21st, 2020 - Few anecdotal cases have been reported in the literature regarding heart transplant recipients and infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). We report our experience with 6 patients hospitalized in Northern Italy during the outbreak. Of the 396 living heart transplant recipients from 1985 to 2020 included in the study, 6 patients developed the novel 2019 coron...
European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery; Hoyos Mejía L, Romero Román A et. al.
Oct 21st, 2020 - We reviewed the incidence of coronavirus disease 2019 cases and the postoperative outcomes of patients who had thoracic surgery during the beginning and at the highest point of transmission in our community. We retrospectively reviewed patients who had undergone elective thoracic surgery from 12 February 2020 to 30 April 2020 and were symptomatic or tested positive for severe acute respiratory ...
Cardiovascular Research; Tanwar V, Adelstein JM et. al.
Oct 21st, 2020 - The coronavirus disease-2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has rapidly grown into a pandemic. According to initial reports, the lungs were thought to be the primary target, but recent case studies have shown its reach can extend to other organs including the heart and blood vessels. The severity of cardiac complications of COVID-19 depends on ...
JAMA Rubin R
Oct 21st, 2020 - The Challenges of Expanding Rapid Tests to Curb COVID-19.|2020|Rubin R,|
European Journal of Nutrition; Arruda de Souza Monnerat J, Ribeiro de Souza P et. al.
Oct 21st, 2020 - The new coronavirus pandemic is affecting the entire world with more than 25 million confirmed cases in August 2020 according to the World Health Organization. It is known that the virus can affect several tissues and can progress to a respiratory failure in severe cases. To prevent the progression to this stage of the disease and minimize all the damage caused by coronavirus (SARS-CoV-2) the i...
Pediatric Radiology; Peng X, Guo Y et. al.
Oct 21st, 2020 - Chest computed tomography (CT) findings in children with coronavirus disease 2019 (COVID-19) have been rarely reported in a comprehensive and systematic manner. We investigated the chest CT findings in children with COVID-19, and explored the differences in these findings between symptomatic patients and asymptomatic patients. Demographic findings, clinical characteristics, duration of hospital...
International Journal of Clinical Oncology; Takahari D, Shinozaki E et. al.
Oct 21st, 2020 - Coronavirus disease 2019 (COVID-19) was declared to be a global pandemic by the World Health Organization on March 11, 2020. On April 7, 2020, a state of emergency was declared in Japan, as had been by other nations worldwide. This unprecedented crisis has profound implications for patients undergoing chemotherapy and for practicing healthcare professionals. Various reports have shown data indi...
Internal and Emergency Medicine; Yahyavi A, Hemmati N et. al.
Oct 21st, 2020 - Targeting the renin-angiotensin system is proposed to affect mortality due to coronavirus disease 2019 (COVID-19). We aimed to compare the mortality rates in COVID-19 patients who received angiotensin-converting enzyme inhibitors or angiotensin receptor blockers (ACEIs/ARBs) and those who did not. In this retrospective cohort study, mortality was considered as the main outcome measure. All unde...
Journal of Medical Virology; Kumar A, Prasoon P et. al.
Oct 21st, 2020 - Paucity of knowledge about SARS-CoV-2 specific virulence factors has greatly hampered therapeutic management of patients with COVID-19. Recently, a cluster of studies appeared, which presented empirical evidence for SARS-CoV-2 specific virulence factors that can explain key elements of COVID-19 pathology. These studies unravel multiple structural and non-structural specifics of SARS-CoV-2, such...
Journal of Medical Virology; Chen Y, Ke Y et. al.
Oct 21st, 2020 - Coronavirus disease 2019 (COVID-19) has rapidly evolved into a global pandemic. A total of 1578 patients admitted into a newly built hospital specialized for COVID-19 treatment in Wuhan, China, were enrolled. Clinical features and the levels of SARS-CoV-2 IgM and IgG were analyzed. In total, 1532 patients (97.2%) were identified as laboratory-confirmed cases. Seventy-seven patients were identif...
Journal of Medical Virology; Mohanty S, Ravindra A et. al.
Oct 21st, 2020 - The unprecedented demand for testing for the ongoing coronavirus disease-2019 (COVID-19) pandemic caused by SARS-CoV-2 has led to an acute shortage and limited availability of test reagents for which pooling of samples has been recommended in areas with low prevalence. Considering the possibility of dilution factor in pool testing, an attempt was made to find out possibility of any true positiv...
Pediatric Dermatology REFERENCES; Andina D, Colmenero I et. al.
Oct 21st, 2020 - A growing number of skin lesions during the COVID-19 pandemic are being recognized. Acral ischemic lesions identical to chilblains are most typical in children and young adults. We report an infant girl, aged 1 month and 29 days, with a peculiar reticulated purpuric eruption on her soles, with positive immunohistochemistry for SARS-CoV-2 in the endothelia of dermal blood vessels. The patient ha...
JAMA Network Open; Gu T, Mack JA et. al.
Oct 21st, 2020 - Black patients are overrepresented in the number of COVID-19 infections, hospitalizations, and deaths in the US. Reasons for this disparity may be due to underlying comorbidities or sociodemographic factors that require further exploration. To systematically determine patient characteristics associated with racial/ethnic disparities in COVID-19 outcomes. This retrospective cohort study used com...
Archives of Virology; Abdollahi H, Rezaei-Tavirani M et. al.
Oct 21st, 2020 - Avian infectious bronchitis virus is one of the most important gammacoronaviruses, which causes a highly contagious disease. In this study, we investigated changes in the proteome of kidney tissue of specific-pathogen-free (SPF) chickens that were infected with an isolate of the nephrotropic variant 2 genotype (IS/1494/06) of avian coronavirus. Twenty 1-day-old SPF White Leghorn chickens were r...
Medicine Salaffi F, Carotti M et. al.
Oct 21st, 2020 - The chest computed tomography (CT) characteristics of coronavirus disease 2019 (COVID-19) are important for diagnostic and prognostic purposes. The aim of this study was to investigate chest CT findings in COVID-19 patients in order to determine the optimal cut-off value of a CT severity score that can be considered a potential prognostic indicator of a severe/critical outcome.The CT findings w...
Medicine Liu Y, Wang M et. al.
Oct 21st, 2020 - The new coronavirus pneumonia Corona Virus Disease 2019 (COVID-19) has become a global pandemic. Patients with critically COVID-19 usually require invasive respiratory support, and the airway management is particularly important and the prognosis is poor. A 64-year-old man with an anastomotic fistula after radical treatment of esophageal cancer and right-side encapsulated pyopneumothorax was ad...
Medicine Xu J, Ma XP et. al.
Oct 21st, 2020 - Unknown origin pneumonia has been furiously spreading since the late of December 2019, subsequently spread to approximately all provinces and areas in China and many countries, which was announced as a Public Health Emergency of International Concern by World Health Organization (WHO). The studies on 2019 Corona Virus Disease-19 (COVID-19) conducted from various fields around the world. Herein,...
Medicine Han L, Wang Y et. al.
Oct 21st, 2020 - The Corona Virus Disease 2019 (COVID-19) is a new acute respiratory infectious disease that has become a major global public health event. In China, the combination of Huashi Baidu Formula (HBF) and antiviral drugs is used in the clinical treatment of severe patients with new coronary pneumonia, but there is still a lack of evidence-based medical evaluation. We search for research in PubMed/MED...
Medicine Zhang B, Wang X et. al.
Oct 21st, 2020 - To study the differences in imaging characteristics and prediction of COVID-19 and non-COVID-19 viral pneumonia through chest CT.Chest CT data of 128 cases of COVID-19 and 47 cases of non-COVID-19 viral pneumonia confirmed by several hospitals were retrospectively collected, the imaging performance was evaluated and recorded, different imaging features were statistically analyzed, and a predict...
Medicine Hu J, Zhou J et. al.
Oct 21st, 2020 - Elevated serum lactate dehydrogenase (LDH) was commonly reported in COVID-19 patients. However, the relationship between LDH and the incidence of severe cases has not been characterized in those patients.We retrospectively analyzed the characteristics of patients from a designated isolation medical center for COVID-19 patients diagnosed from February 6 to March 1. Variables accessed within 48 h...
Oct 21st, 2020 - Analysis of type I IFN response and T cell activation in severe COVID-19/HIV-1 coinfection: A case report: Erratum.|2020||
International Journal of Environmental Research and Public Health; Faes C, Abrams S et. al.
Oct 21st, 2020 - There are different patterns in the COVID-19 outbreak in the general population and amongst nursing home patients. We investigate the time from symptom onset to diagnosis and hospitalization or the length of stay (LoS) in the hospital, and whether there are differences in the population. Sciensano collected information on 14,618 hospitalized patients with COVID-19 admissions from 114 Belgian ho...
International Journal of Environmental Research and Public Health; Bogdanova E, Andronov S et. al.
Oct 21st, 2020 - This article presents the challenges facing reindeer herding as being both a profitable business and part of the traditional culture of the nomadic Indigenous peoples in the Arctic zone of Western Siberia which addresses substantial needs of the local population. Reindeer herding products are used as traditional nutrition, and as effective preventive means and remedies for adapting to the cold ...
International Journal of Environmental Research and Public Health; Cohen O, Mahagna A et. al.
Oct 21st, 2020 - Previous studies of minority groups in times of emergency have tended to focus on risk reduction or on individual resilience, overlooking the community factors that could be bolstered to promote better health and safety outcomes. The current study aimed to examine the role of health-care services in the perceived community resilience of urban and suburban Arab communities in Israel during the C...
International Journal of Environmental Research and Public Health; Lee SM, Lee D
Oct 21st, 2020 - The COVID-19 pandemic has swept the world like a gigantic tsunami, turning social and economic activities upside down. This paper presents some of the innovative response strategies implemented by the public health system, healthcare facilities, and government in South Korea, which has been hailed as the model country for its success in containing COVID-19. Korea reinvented its public health in...
International Journal of Environmental Research and Public Health; Tran BL, Chen CC et. al.
Oct 21st, 2020 - This study examines how experience of severe acute respiratory syndrome (SARS) influences the impact of coronavirus disease (COVID-19) on international tourism demand for four Asia-Pacific Economic Cooperation (APEC) economies, Taiwan, Hong Kong, Thailand, and New Zealand, over the 1 January-30 April 2020 period. To proceed, panel regression models are first applied with a time-lag effect to es...
The Journal of International Medical Research; Micarelli A, Granito I et. al.
Oct 21st, 2020 - To survey perceived general and ear-nose-throat (ENT) symptoms of COVID-19 in relation to psychological impact, mental health, perception of information and demographic characteristics in quarantined subjects during a lockdown period in Italy. Participants were 1380 respondents who completed an online survey. A logistic regression model was used to evaluate the association between the independe...
Journal of Telemedicine and Telecare; Pierce RP, Stevermer JJ
Oct 21st, 2020 - The coronavirus disease 2019 (COVID-19) pandemic resulted in an unprecedented expansion in telehealth, but little is known about differential use of telehealth according to demographics, rurality, or insurance status. We performed a cross-sectional analysis of 7742 family medicine encounters at a single USA institution in the initial month of the COVID-19 public health emergency (PHE). We compa...
Journal of Telemedicine and Telecare; Fraticelli F, Nicola MD et. al.
Oct 21st, 2020 - Obesity and type 2 diabetes (T2D) are two closely related pandemic conditions. Novel technologies represent promising tools for their management, the use of which has been greatly encouraged during the COVID-19 pandemic. The aim of the present study is to compare a web-based nutritional intervention versus a traditional one, before and during the Italian 'lockdown' period due to the COVID-19 ou...
Journal of Aging & Social Policy; Moorman S, Boerner K et. al.
Oct 21st, 2020 - Advance care planning (ACP) for medical decision-making at the end of life has developed around the expectation of death from long-term, progressive chronic illnesses. We reexamine advance care planning in light of the increased probability of death from COVID-19, an exemplar of death that occurs relatively quickly after disease onset. We draw several conclusions about ACP in the context of inf...
Current Drug Targets; Vieira C, Nery L et. al.
Oct 21st, 2020 - The Coronavirus Disease 2019 (COVID-19) is becoming the major health issue in recent human history with thousands of deaths and millions of cases worldwide. Newer research and old experience with other corona-viruses highlighted a probable underlying mechanism of disturbance of the renin-angiotensin system (RAS) that is associ-ated with intrinsic effects of SARS-CoV-2 infection. In this review,...
BMC Medical Imaging; Cai Q, Du SY et. al.
Oct 21st, 2020 - Coronavirus disease 2019 (COVID-19) has emerged as a global pandemic. According to the diagnosis and treatment guidelines of China, negative reverse transcription-polymerase chain reaction (RT-PCR) is the key criterion for discharging COVID-19 patients. However, repeated RT-PCR tests lead to medical waste and prolonged hospital stays for COVID-19 patients during the recovery period. Our purpose...
BMC Infectious Diseases; Xiang J, Chen Z et. al.
Oct 21st, 2020 - Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has become a public health emergency of international concern. SARS-CoV-2 RNA detection is the diagnostic criterion for coronavirus disease 2019 (COVID-19). Nevertheless, RNA detection has many limitations, such as being time-consuming and cost-prohibitive, and it must be performed in specialized laboratories. Virus antibody...
BMC Infectious Diseases; Österdahl MF, Lee KA et. al.
Oct 21st, 2020 - A cost effective and efficient diagnostic tool for COVID-19 as near to the point of care (PoC) as possible would be a game changer in the current pandemic. We tested reverse transcription loop mediated isothermal amplification (RT-LAMP), a method which can produce results in under 30 min, alongside standard methods in a real-life clinical setting. This prospective service improvement project pi...
BMC Infectious Diseases; Lin S, Pan H et. al.
Oct 21st, 2020 - In December 2019, the outbreak of coronavirus disease 2019 (COVID-19) began in Wuhan, China, and rapidly spread to other regions. We aimed to further describe the epidemiological and clinical characteristics of discharged COVID-19 cases and evaluate the public health interventions. We collected epidemiological and clinical data of all discharged COVID-19 cases as of 17 February 2020 in Shanghai...
BMC Psychiatry; Nissen JB, Højgaard DRMA et. al.
Oct 21st, 2020 - Obsessive compulsive disorder (OCD) is a distressing psychiatric disorder. Traumas may trigger or aggravate OCD symptoms. COVID-19 pandemic has coursed a global crisis and has been associated with onset of psychiatric disorders in adults. Little is known about children/adolescents with OCD. The present study aimed to examine how children/adolescents with OCD react towards COVID-19 crisis. A que...
BMC Public Health; Rosenbaum JE, Jennings J et. al.
Oct 21st, 2020 - Syphilis and gonorrhea reached an all-time high in 2018. The resurgence of syphilis and gonorrhea requires innovative methods of sexual contact tracing that encourage disclosure of same-sex sexual contacts that might otherwise be suppressed. Over 75% of Grindr mobile phone application users report seeking "friendship," so this study asked people diagnosed with syphilis and gonorrhea to identify...
Globalization and Health; Kohler JC, Bowra A
Oct 21st, 2020 - Corruption is recognized by the global community as a threat to development generally and to achieving health goals, such as the United Nations Sustainable Development Goal # 3: ensuring healthy lives and promoting well-being for all. As such, international organizations such as the World Health Organizations and the United Nations Development Program are creating an evidence base on how best t...