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Advances and challenges in Nintedanib drug delivery.
https://doi.org/10.1080/17425247.2021.1985460
Expert Opinion on Drug Delivery; Velagacherla V, Suresh A et. al.

Sep 25th, 2021 - Nintedanib (NTB) is an orally administered tyrosine kinase inhibitor that has been approved recently by USFDA for idiopathic pulmonary fibrosis (IPF) and systemic sclerosis-associated interstitial lung disease (SSc-ILD). NTB is also prescribed in COVID-19 patients associated with IPF. However, it has an extremely low bioavailability of around 4.7% hence researchers are attempting to address thi...

The host immune response of a discharged COVID-19 patient with twice reemergence of SAR...
https://doi.org/10.1186/s12879-021-06679-3 10.1016/j.cell.2020.10.049 10.1007/s11427-020-1661-4 10.1002/jmv.26114 10.1080/22221751.2020.1852058 10.1016/j.ebiom.2020.102960 10.1080/22221751.2020.1762515 10.1080/22221751.2020.1729071 10.1016/j.cell.2020.10.001 10.1093/infdis/jiaa252 10.1016/S0140-6736(20)32656-8
BMC Infectious Diseases; Zao X, Zhou Y et. al.

Sep 25th, 2021 - The coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has become a global pandemic. There have been reports that long-term SARS-CoV-2 RNA shedding and re-infection of COVID-19 patients existed. However, the specific mechanism, diagnosis, and treatment of COVID-19 are still unclarified. In this case, we reported a 64-year-old patient who h...

The impact of the COVID-19 pandemic on patterns of attendance at emergency departments ...
https://doi.org/10.1186/s12913-021-07008-9 10.1136/emermed-2020-209980 10.1016/S0140-6736(20)31356-8 10.1016/j.puhe.2020.04.046 10.1186/s12873-020-00395-y 10.1038/s41598-021-81930-0
BMC Health Services Research; Vollmer MAC, Radhakrishnan S et. al.

Sep 25th, 2021 - Hospitals in England have undergone considerable change to address the surge in demand imposed by the COVID-19 pandemic. The impact of this on emergency department (ED) attendances is unknown, especially for non-COVID-19 related emergencies. This analysis is an observational study of ED attendances at the Imperial College Healthcare NHS Trust (ICHNT). We calibrated auto-regressive integrated mo...

COVID-19 Pediatric Dermatology.
https://doi.org/10.1016/j.det.2021.05.012
Dermatologic Clinics; Neale H, Hawryluk EB

Sep 25th, 2021 - Children are a unique subset of patients in relation to the COVID-19 pandemic, often presenting asymptomatically, mildly, or atypically. Manifestations of the skin may be a primary (or the only) presenting sign. Recognizing cutaneous manifestations of COVID-19 in the pediatric population is important to guiding precautions, testing, and management for patients and close contacts. Whereas some d...

Clinical Patterns and Morphology of COVID-19 Dermatology.
https://doi.org/10.1016/j.det.2021.05.006
Dermatologic Clinics; Agnihothri R, Fox LP

Sep 25th, 2021 - Coronavirus disease 2019 (COVID-19), an emergent disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has rapidly spread throughout the globe since its discovery in December 2019. Although first appreciated to cause pneumonia, numerous organ systems are now known to be involved. The objective of this article is to review the broad spectrum of cutaneous manifestations ...

Cutaneous Pathology of COVID-19 as a Window into Immunologic Mechanisms of Disease.
https://doi.org/10.1016/j.det.2021.05.008
Dermatologic Clinics; Gallman AE, Fassett MS

Sep 25th, 2021 - Many skin manifestations of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection reflect activation of cutaneous and systemic immune responses involving effector pathways of both the innate and adaptive arms of the immune system. This article reviews evidence from the recent clinical and scientific literature that informs the current understanding of the consequences of corona...

Cutaneous Manifestations of COVID-19 in the Inpatient Setting.
https://doi.org/10.1016/j.det.2021.05.011
Dermatologic Clinics; Do MH, Stewart CR et. al.

Sep 25th, 2021 - Cutaneous findings have increasingly been reported in patients with coronavirus disease 2019 (COVID-19). This review discusses associated skin findings in patients with COVID-19 in the inpatient setting, ranging from vasculopathy-related lesions associated with high hospitalization rate and poor prognosis to inflammatory vesicular and urticarial eruptions that are rarely associated with prolong...

Coronavirus Disease 2019 and Race in Dermatology.
https://doi.org/10.1016/j.det.2021.05.003
Dermatologic Clinics; Desai SR, McMichael AJ et. al.

Sep 25th, 2021 - Coronavirus Disease 2019 disproportionately affects Black and Hispanic/Latino populations. Racial disparities inherently exist in dermatology because of underrepresentation of skin of color populations in literature, reduced access to care for minority populations, and low diversity within the specialty of dermatology itself. Lack of imagery in dermatology can have detrimental consequences for ...

Occupational Dermatoses Related to Personal Protective Equipment Used During the COVID-...
https://doi.org/10.1016/j.det.2021.05.009
Dermatologic Clinics; Abdali S, Yu J

Sep 25th, 2021 - The recent coronavirus disease 2019 (COVID-19) pandemic has led to the dramatic increase in use of personal protective equipment (PPE) among health care providers and the general public. Herein the authors discuss the various occupational dermatoses including allergic and irritant contact dermatitis, acne, seborrheic dermatitis, and rosacea related to frequent handwashing, disinfecting of surfa...

The Use of Biologics During the COVID-19 Pandemic.
https://doi.org/10.1016/j.det.2021.05.010
Dermatologic Clinics; Jones ME, Kohn AH et. al.

Sep 25th, 2021 - During the coronavirus disease 2019 (COVID-19) pandemic, there has been considerable discussion regarding the use of biologics in patients with inflammatory skin conditions, such as psoriasis, hidradenitis suppurativa, and atopic dermatitis. This article discusses clinical trial data, real-world evidence, and guidelines and recommendations for biologics that inhibit tumor necrosis factor, inter...

Impact of COVID-19 on Dermatology Residency.
https://doi.org/10.1016/j.det.2021.05.002
Dermatologic Clinics; Samimi S, Choi J et. al.

Sep 25th, 2021 - COVID-19 has created challenges across medicine, including in medical education, with deeply rooted impacts in the dermatology residency experience. Its effects are both acute and chronic, including: shifts to virtual education and conferences, skewed clinical experiences, negatively impacted wellness, and uncertainty in the future. As educators and mentors, it is important to recognize and add...

Dermatology COVID-19 Registries: Updates and Future Directions.
https://doi.org/10.1016/j.det.2021.05.013
Dermatologic Clinics; Freeman EE, Chamberlin GC et. al.

Sep 25th, 2021 - During the COVID-19 pandemic, rapid, real-world evidence is essential for the development of knowledge and subsequent public health response. In dermatology, provider-facing and patient-facing registries focused on COVID-19 have been important sources of research and new information aimed at guiding optimal patient care. The 7 dermatology registries included in this update now include more than...

Coronavirus Disease 2019 and Dermatology Practice Changes.
https://doi.org/10.1016/j.det.2021.05.004
Dermatologic Clinics; Torres AE, Ozog DM et. al.

Sep 25th, 2021 - The impact of the COVID-19 pandemic on dermatology practice cannot be overstated. At its peak, the pandemic resulted in the temporary closure of ambulatory sites as resources were reallocated towards pandemic response efforts. Many outpatient clinics have since reopened and are beginning to experience a semblance of pre-pandemic routine, albeit with restrictions in place. We provide an overview...

The Impact of COVID-19 on Teledermatology: A Review.
https://doi.org/10.1016/j.det.2021.05.007
Dermatologic Clinics; Yeboah CB, Harvey N et. al.

Sep 25th, 2021 - The accelerated implementation and use of teledermatology during the coronavirus disease 2019 pandemic has met with successes and challenges. This review explores how telemedicine was used in dermatology before the pandemic, the regulatory adaptions made in response to the pandemic, and the effectiveness of the rapid implementation of teledermatology during the coronavirus disease 2019 pandemic...

Effect of the COVID-19 Pandemic on Delayed Skin Cancer Services.
https://doi.org/10.1016/j.det.2021.05.015
Dermatologic Clinics; Rashid S, Tsao H

Sep 25th, 2021 - The COVID-19 pandemic has presented a unique set of challenges to cancer care centers around the world. Diagnostic and treatment delays associated with lockdown periods may be expected to increase the total number of avoidable skin cancer deaths. During this unprecedented time, dermatologists have been pressed to balance early surgical interventions for skin cancer with the risk of viral transm...

The Impact of the COVID-19 Pandemic on Global Health Dermatology.
https://doi.org/10.1016/j.det.2021.05.005
Dermatologic Clinics; Hannah C, Williams V et. al.

Sep 25th, 2021 - In this article, we discuss the impact of the COVID-19 pandemic on various areas of global health dermatology, including patient care, neglected tropical diseases, education, and collaborations. Information was collected from literature review and informal interviews with more than 20 dermatologists from around the world. Many of the setbacks and hardships experienced by the global health commu...

COVID-19 and Dermatology: One Year in Review.
https://doi.org/10.1016/j.det.2021.06.001
Dermatologic Clinics; Freeman EE, McMahon DE

Sep 25th, 2021 - COVID-19 and Dermatology: One Year in Review.|2021|Freeman EE,McMahon DE,|

Atrial Arrhythmias and the Pandemic.
https://doi.org/10.1016/j.jacep.2021.03.011
JACC. Clinical Electrophysiology; Chinitz LA

Sep 25th, 2021 - Atrial Arrhythmias and the Pandemic.|2021|Chinitz LA,|

The changing epidemiology of acute kidney injury syndromes in the face of emerging resp...
https://doi.org/10.1016/j.kint.2021.07.001
Kidney International; Thakkar J, Golestaneh L

Sep 25th, 2021 - In this issue, Birkelo et al. performed a rigorous analysis of acute kidney injury (AKI) differences in patients hospitalized with coronavirus disease 2019 versus influenza. Coronavirus disease 2019 AKI was more severe, with worse outcomes, than influenza, despite adjustment for confounders. Their findings highlight the need for development of a new category of AKI syndrome, "viral pandemic-ass...

Is Early COVID-19 in Kidney Transplant Recipients Concerning Enough to Halt Transplanta...
https://doi.org/10.1016/j.transproceed.2021.08.034
Transplantation Proceedings; Meshram HS, Kute VB et. al.

Sep 25th, 2021 - Limited data exist on the incidence and outcome of early coronavirus disease 2019 (COVID-19) in kidney transplantation recipients (KTR). A retrospective multicenter research study was conducted across 12 centers in India. We explored the symptomatology, demographic, laboratory findings, and outcome of COVID-19 within 30 days of transplantation. The outcome was compared with the overall KTR and ...

Covid-19 vaccination: evidence of waning immunity is overstated.
https://doi.org/10.1136/bmj.n2320
BMJ (Clinical Research Ed.); Scott J, Richterman A et. al.

Sep 25th, 2021 - Covid-19 vaccination: evidence of waning immunity is overstated.|2021|Scott J,Richterman A,Cevik M,|

Update to living WHO guideline on drugs for covid-19.
https://doi.org/10.1136/bmj.n2219
BMJ (Clinical Research Ed.);

Sep 25th, 2021 - Update to living WHO guideline on drugs for covid-19.|2021||

Covid-19: Rich countries' booster plans will impede global vaccination, experts say.
https://doi.org/10.1136/bmj.n2353
BMJ (Clinical Research Ed.); Dyer O

Sep 25th, 2021 - Covid-19: Rich countries' booster plans will impede global vaccination, experts say.|2021|Dyer O,|

B-cell targeted therapy is associated with severe COVID-19 among patients with inflamma...
https://doi.org/10.1136/annrheumdis-2021-220549
Annals of the Rheumatic Diseases; Felten R, Duret PM et. al.

Sep 25th, 2021 - B-cell targeted therapy is associated with severe COVID-19 among patients with inflammatory arthritides: a 1-year multicentre study in 1116 successive patients receiving intravenous biologics.|2021|Felten R,Duret PM,Bauer E,Sedmak N,Djossou JH,|

Antibody and cellular therapies for treatment of covid-19: a living systematic review a...
https://doi.org/10.1136/bmj.n2231
BMJ (Clinical Research Ed.); Siemieniuk RA, Bartoszko JJ et. al.

Sep 25th, 2021 - To evaluate the efficacy and safety of antiviral antibody therapies and blood products for the treatment of novel coronavirus disease 2019 (covid-19). Living systematic review and network meta-analysis, with pairwise meta-analysis for outcomes with insufficient data. WHO covid-19 database, a comprehensive multilingual source of global covid-19 literature, and six Chinese databases (up to 21 Jul...

Temporary hold of mycophenolate augments humoral response to SARS-CoV-2 vaccination in ...
https://doi.org/10.1136/annrheumdis-2021-221252
Annals of the Rheumatic Diseases; Connolly CM, Chiang TP et. al.

Sep 25th, 2021 - Temporary hold of mycophenolate augments humoral response to SARS-CoV-2 vaccination in patients with rheumatic and musculoskeletal diseases: a case series.|2021|Connolly CM,Chiang TP,Boyarsky BJ,Ruddy JA,Teles M,|

Impact of restricted visitation policies in hospitals on patients, family members and h...
https://doi.org/10.1136/bmjopen-2020-048227
BMJ Open; Moss SJ, Stelfox HT et. al.

Sep 25th, 2021 - Flexible visitation policies in hospitals are an important component of care that contributes to reduced stress and increased satisfaction among patients and their family members. Early evidence suggests restricted visitation policies enacted in hospitals during the COVID-19 pandemic are having unintended consequences on patients, family members and healthcare providers. There is a need for a c...

Seroprevalence of SARS-CoV-2-specific IgG antibodies in Kashmir, India, 7 months after ...
https://doi.org/10.1136/bmjopen-2021-053791
BMJ Open; Khan SMS, Qurieshi MA et. al.

Sep 25th, 2021 - We designed a population-based survey in Kashmir to estimate the seroprevalence of SARS-CoV-2-specific IgG antibodies in the general population aged 18 years and above. The survey was conducted among 110 villages and urban wards across 10 districts in Kashmir from 17 October 2020 to 4 November 2020. Individuals aged 18 years and above were eligible to be included in the survey. Serum samples we...

Comparison of deliberate self-harm incidents attended by Helicopter Emergency Medical S...
https://doi.org/10.1136/emermed-2020-210393
Emergency Medicine Journal : EMJ; Stevens J, Price J et. al.

Sep 25th, 2021 - There is significant interest in the mental health impact of the COVID-19 pandemic. Helicopter Emergency Medical Services (HEMS) attend the most seriously unwell and injured patients in the community; their data therefore present an early opportunity to examine self-harm trends. The primary aim was to compare the incidence of deliberate self-harm incident (DSH-I) encounters by HEMS before and d...

Rare case of COVID-19 vaccine-associated intracranial haemorrhage with venous sinus thr...
https://doi.org/10.1136/bcr-2021-245092
BMJ Case Reports; Purkayastha P, Mckechnie C et. al.

Sep 25th, 2021 - Vaccine-induced immune thrombotic thrombocytopenia (VITT) is a relatively novel term which describes patients who have developed a low platelet count and prothrombotic tendencies secondary to receiving a vaccine. The concept has been derived from the well-established phenomenon of heparin-induced thrombocytopenia, and several cases of VITT have now been reported in patients who have received th...

Multiple Cardiovascular Diseases or Risk Factors Increase the Severity of Coronavirus D...
https://doi.org/10.1253/circj.CJ-21-0684
Circulation Journal : Official Journal of the Japanese Ci... Yamada T, Ogawa T et. al.

Sep 25th, 2021 - This study aimed to determine whether disease severity varied according to whether coronavirus disease 2019 (COVID-19) patients had multiple or single cardiovascular diseases and risk factors (CVDRFs).Methods and Results:COVID-19 patients with single (n=281) or multiple (n=412) CVDRFs were included retrospectively. Multivariable logistic regression showed no significant difference in the risk o...

Substance and Internet use during the COVID-19 pandemic in China.
https://doi.org/10.1038/s41398-021-01614-1 10.3389/fpsyt.2020.00714 10.1192/j.eurpsy.2020.78 10.1016/j.jpsychires.2020.05.026 10.1016/j.jad.2020.05.080 10.15585/mmwr.mm6932a1 10.1001/archinte.166.10.1092 10.1111/j.1360-0443.2009.02526.x 10.4306/pi.2017.14.6.871 10.1111/j.1360-0443.2006.01481.x 10.7326/M20-1212 10.1080/08897077.2020.1784363 10.1378/chest.12-0930 10.1080/02791072.2017.1397304 10.1016/j.psychres.2020.113096 10.1111/ajad.13066 10.3389/fpsyt.2020.597826 10.1111/pcn.13127 10.1016/j.drugalcdep.2018.03.008 10.1001/archpsyc.59.4.375 10.1016/j.psychres.2020.113407 10.1186/1471-2458-8-92 10.1001/archinte.166.10.1092 10.3810/pgm.2010.07.2173 10.1016/j.eplepsyres.2015.11.019 10.1046/j.1525-1497.2001.016009606.x 10.1111/appy.12063 10.1016/j.genhosppsych.2014.05.021 10.1159/000510822 10.3389/fpsyt.2020.572245 10.1111/add.15295 10.1016/j.ajp.2020.102064 10.15288/jsad.2008.69.695 10.3389/fpsyt.2020.00751 10.1080/07448481.2013.843536 10.1016/j.addbeh.2012.12.005 10.1016/j.neubiorev.2017.01.026 10.1556/2006.2020.00016 10.1590/1413-81232020256.1.11472020 10.1002/embr.201338222 10.2188/jea.JE20160185 10.7717/peerj.10827 10.3389/fpsyt.2020.598585 10.4306/pi.2014.11.4.380 10.1556/JBA.3.2014.003 10.1089/cyber.2010.0410 10.3390/ijerph8093528 10.1037/adb0000160 10.1016/j.invent.2020.100345 10.1007/s00787-020-01541-4 10.1111/pcn.13105 10.1111/bjhp.12430 10.3389/fpsyg.2020.559819 10.1146/annurev-publhealth-032013-182435 10.1089/cyber.2016.0669 10.3389/fpsyt.2020.00352 10.1097/01.nmd.0000146911.52616.22 10.1016/S0140-6736(20)30309-3 10.1016/j.addbeh.2020.106754
Translational Psychiatry; Huang Q, Chen X et. al.

Sep 25th, 2021 - The coronavirus disease 2019 (COVID-19) has adversely influenced human physical and mental health, including emotional disorders and addictions. This study examined substance and Internet use behavior and their associations with anxiety and depression during the COVID-19 pandemic. An online self-report questionnaire was administered to 2196 Chinese adults between February 17 and 29, 2020. The q...

SARS-CoV-2 mucosal antibody development and persistence and their relation to viral loa...
https://doi.org/10.1038/s41467-021-25949-x 10.1016/j.cmi.2020.04.040 10.1056/NEJMe2009758 10.1056/NEJMoa2008457 10.3201/eid2702.203517 10.1038/s41467-020-19545-8 10.1056/NEJMoa2034577 10.1038/s41586-020-2639-4 10.1128/JVI.00647-20 10.1172/jci.insight.142386 10.4049/jimmunol.180.2.948 10.1128/JVI.80.8.4079-4087.2006 10.1038/s41591-020-0868-6 10.1016/j.cell.2020.05.042 10.1038/s41564-020-00813-8 10.1371/journal.pone.0240205 10.1093/infdis/jis033 10.1016/j.jcv.2014.04.017 10.1038/s41467-020-16256-y 10.1093/infdis/jiaa479 10.18637/jss.v082.i13
Nature Communications; Fröberg J, Gillard J et. al.

Sep 25th, 2021 - Although serological studies have shown that antibodies against SARS-CoV-2 play an important role in protection against (re)infection, the dynamics of mucosal antibodies during primary infection and their potential impact on viral load and the resolution of disease symptoms remain unclear. During the first pandemic wave, we assessed the longitudinal nasal antibody response in index cases with m...

Electrical impedance tomography clues to detect pulmonary thrombosis in a teenager with...
https://doi.org/10.1007/s00247-021-05199-1 10.3389/fped.2017.00170 10.1111/jth.14849 10.1056/NEJMoa1909159 10.1038/s41598-019-41774-1 10.1155/2013/529038 10.1088/0967-3334/33/5/695 10.1007/s00134-010-2049-4
Pediatric Radiology; Foronda FAK, Fernandes LR et. al.

Sep 25th, 2021 - We report a case of pulmonary thrombosis in a teenager during a hypercoagulable state associated with COVID-19 (coronavirus disease 2019) caused by SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2). A condition rare in children and adolescents, pulmonary thrombosis underdiagnosis likely increases morbidity and mortality. A pulmonary thrombosis diagnosis requires a high level of suspi...

Pandemic Tic-like Behaviors Following Social Media Consumption.
https://doi.org/10.1002/mds.28800
Movement Disorders : Official Journal of the Movement Dis... Paulus T, Bäumer T et. al.

Sep 25th, 2021 - Currently, there is a marked increase of young people with sudden onset of tic-like behaviors (TLBs) resembling movements and vocalizations presented on social media videos as "Tourette's syndrome." To delineate clinical phenomenology of TLBs after social media exposure in comparison with clinical features of Tourette's syndrome. We compared demographic and clinical variables between 13 patient...

Beneficial and Harmful Outcomes of Tocilizumab in Severe COVID-19: A Systematic Review ...
https://doi.org/10.1002/phar.2627
Pharmacotherapy Rubio-Rivas M, Forero CG et. al.

Sep 25th, 2021 - The results of studies of tocilizumab (TCZ) in COVID-19 are contradictory. Our study aims to update the medical evidence from controlled observational studies and randomized clinical trials (RCT) on the use of TCZ in hospitalized patients with COVID-19. We searched the following databases from January 1, 2020 to April 13, 2021 (date of the last search): MEDLINE database through the PubMed searc...

Home Low Vision Ocular Rehabilitation Telehealth Expansion Due to COVID-19 Pandemic.
https://doi.org/10.1089/tmj.2021.0264
Telemedicine Journal and E-health : the Official Journal ... Ihrig C

Sep 25th, 2021 - Background: In March 2020, the pandemic added a major barrier resulting in the cancelation of all low vision ocular rehabilitation services. To prevent delay of beginning low vision ocular rehabilitation services, all low vision care was switched to telerehabilitation to home. Methods: Case managers began to cancel all in-person services and offer Veterans Affairs (VA) video connect services to...

Outcomes of stent-graft repair for anastomotic femoral pseudoaneurysm. A case series.
https://doi.org/10.1177/17085381211045194
Vascular Franchin M, Fontana F et. al.

Sep 25th, 2021 - This study aims to report a case series of anastomotic femoral pseudoaneurysms (PSA) treated with stent-grafting (SG) in patients at high-risk for the open surgical approach. It is a retrospective, observational cohort study. Between 1 January 2002 and 1 April 2020, post-hoc analysis of the database including patients who received repair for femoral PSA identified those treated with SG. All but...

Postmortem Stability of SARS-CoV-2 in Mouse Lung Tissue.
https://doi.org/10.3201/eid2712.211621
Emerging Infectious Diseases; Valkenburg SA, Cheng SMS et. al.

Sep 25th, 2021 - The infectivity of severe acute respiratory syndrome coronavirus 2 in deceased persons and organisms remains unclear. We studied transgenic K18 hACE2 mice to determine the kinetics of virus infectivity after host death. Five days after death, virus infectivity in the lung declined by >96% and RNA copies declined by 48.2%.

Predictors of acute deep venous thrombosis in patients hospitalized for COVID-19.
https://doi.org/10.1097/MD.0000000000027216
Medicine Riyahi S, Hectors SJ et. al.

Sep 25th, 2021 - Deep venous thrombosis (DVT) is associated with high mortality in coronavirus disease 2019 (COVID-19) but there remains uncertainty about the benefit of anti-coagulation prophylaxis and how to decide when ultrasound screening is indicated. We aimed to determine parameters predicting which COVID-19 patients are at risk of DVT and to assess the benefit of prophylactic anti-coagulation.Adult hospi...

Pediatric onco-hematological home care during COVID-19 pandemic.
https://doi.org/10.1007/s00520-021-06571-5 10.1002/pbc.23047 10.1258/135581906776318947 10.1016/j.jpainsymman.2020.03.021 10.1016/j.jpainsymman.2020.11.026 10.1017/S1478951518000238 10.1017/S1478951519000543 10.1002/pbc.28505
Supportive Care in Cancer : Official Journal of the Multi... Amicucci M, Piccioni F et. al.

Sep 25th, 2021 - The aim of the work is to describe the protocol adopted by the Home Care Service in pediatric onco-hematological patients of a large cancer institute in Italy during COVID-19 pandemic and to present preliminary data. Based on our experience, we have developed strategies to ensure continuity of care, non-abandonment, and protection of patients and operators in a period of emergency like this. In...

The Second Wave of the COVID-19 Tsunami and Mental Health: An Indian Perspective.
https://doi.org/10.4088/PCC.21com02995
The Primary Care Companion for CNS Disorders; Singh GP

Sep 25th, 2021 - The Second Wave of the COVID-19 Tsunami and Mental Health: An Indian Perspective.|2021|Singh GP,|

Astronomical Use of Nitrous Oxide Associated With Stress From the COVID-19 Pandemic and...
https://doi.org/10.4088/PCC.21cr03022
The Primary Care Companion for CNS Disorders; Cape MC, Kiyokawa M et. al.

Sep 25th, 2021 - Astronomical Use of Nitrous Oxide Associated With Stress From the COVID-19 Pandemic and Lockdown.|2021|Cape MC,Kiyokawa M,Haning WF,|

Cytometric analysis of patients with COVID-19: what is changed in the second wave?
https://doi.org/10.1186/s12967-021-03072-1 10.1056/NEJMcp2009249 10.1056/NEJMcp2009575 10.1016/j.lfs.2020.118355 10.3389/fimmu.2020.607069 10.1183/13993003.02182-2020 10.1016/j.intimp.2021.107586 10.3389/fimmu.2021.655934 10.1371/journal.ppat.1009448 10.1016/j.it.2020.11.002 10.3390/ijerph17238708 10.1007/s40520-020-01764-0 10.1080/23744235.2021.1884745 10.1056/NEJMoa2021436 10.1007/s40264-020-00976-7 10.1515/cclm-2020-0442 10.3390/diagnostics11020288 10.1097/CCM.0000000000004741 10.1016/S1473-3099(20)30483-7 10.1038/s41577-020-00421-x 10.7150/ijbs.47652 10.3389/fimmu.2018.00302 10.1182/bloodadvances.2020002650 10.1007/s40618-021-01565-w 10.3389/fpubh.2021.664108 10.1002/JLB.4COVCRA0820-481RRR 10.1196/annals.1321.010 10.1016/j.jmii.2019.10.001 10.3389/fimmu.2020.556579 10.3389/fimmu.2020.00827 10.1038/s41423-020-0402-2 10.1111/imm.13262 10.4049/jimmunol.2000554 10.1111/bcp.14437 10.1038/s41577-020-0328-z 10.1111/bph.15452 10.2340/00015555-3816 10.1111/bjd.17580 10.1073/pnas.2005615117
Journal of Translational Medicine; Scalia G, Raia M et. al.

Sep 25th, 2021 - Coronavirus disease 2019 (COVID-19) pandemic had a 1st wave in Europe from March to May 2020 and a 2nd wave since September 2020. We previously studied 35 hospitalized COVID-19 patients of the 1st wave demonstrating a cytokine storm and the exhaustion of most lymphocyte subpopulations. Herein, we describe the results obtained from COVID-19 patients of the 2nd wave. We analyzed interleukin (IL)-...

Safety of elective abdominal and vascular surgery during the COVID-19 pandemic: a retro...
https://doi.org/10.1186/s40001-021-00583-x 10.1007/s00423-020-01888-x 10.1002/bjs.11646 10.1016/j.bja.2020.05.037 10.1093/cid/ciaa816 10.15585/mmwr.mm6915e5 10.1001/jama.2020.1585 10.1001/jamanetworkopen.2020.9666 10.1016/S0140-6736(20)31182-X 10.1016/j.eclinm.2020.100331 10.1001/jamasurg.2020.2713 10.1056/NEJMms2009984 10.2807/1560-7917.ES.2020.25.3.2000045 10.1016/S0140-6736(20)30211-7 10.1002/jmv.26770 10.1007/s42399-020-00363-4 10.1111/anae.15281 10.1016/j.surg.2020.05.006 10.1007/s00268-020-05722-9 10.7189/jogh.10.020507 10.1097/SLA.0000000000004218 10.1002/jso.26187 10.1007/s00268-020-05720-x 10.1200/JCO.20.01933
European Journal of Medical Research; Flemming S, Hankir MK et. al.

Sep 25th, 2021 - Patients with coronavirus disease 2019 (COVID-19) who undergo surgery have impaired postoperative outcomes and increased mortality. Consequently, elective and semi-urgent operations on the increasing number of patients severely affected by COVID-19 have been indefinitely postponed.in many countries with unclear implications on disease progression and overall survival. The purpose of this study ...

COVID-19 Vaccines and the Skin: The Landscape of Cutaneous Vaccine Reactions Worldwide.
https://doi.org/10.1016/j.det.2021.05.016
Dermatologic Clinics; Sun Q, Fathy R et. al.

Sep 25th, 2021 - In 2021, we entered a new phase of the COVID-19 pandemic. As mass vaccinations are underway and more vaccines are approved, it is important to recognize cutaneous adverse events. We review the dermatologic manifestations of COVID-19 vaccines as reported in clinical trial data and summarize additional observational reports of skin reactions to COVID-19 vaccines. Early-onset local injection react...

Less Exposure for Health Care Workers, More Comfort for Patients During COVID-19 Swab T...
https://doi.org/10.1177/21650799211045309
Workplace Health & Safety; Karaca A, Akçimen M et. al.

Sep 25th, 2021 - Nasopharyngeal (NP) and oropharyngeal (OP) swab sampling for coronavirus disease 2019 (COVID-19) diagnosis may lead to droplet and/or airborne particle transmission and increase the exposure risk for health care workers (HCWs). However, there is limited evidence for effective methods to reduce occupational exposure from NP and OP swab sampling. This study aimed to reduce droplet-forming respons...

Approach to the patient: Early post-renal transplant hyperglycemia.
https://doi.org/10.1210/clinem/dgab697
The Journal of Clinical Endocrinology and Metabolism; Iqbal A, Zhou K et. al.

Sep 25th, 2021 - Though post-transplant diabetes mellitus (PTDM, occurring >45 days after transplantation) and its complications are well-described, early post-renal transplant hyperglycemia (EPTH) (<45 days) similarly puts kidney transplant recipients at risk of infections, re-hospitalizations, graft failure and is not emphasized much in the literature. Proactive screening and management of EPTH is required gi...

WHO guidance to support HIV care models during the Covid-19 era.
https://doi.org/10.1093/cid/ciab855
Clinical Infectious Diseases : an Official Publication Of... Ford N, Vitoria M et. al.

Sep 25th, 2021 - WHO guidance to support HIV care models during the Covid-19 era.|2021|Ford N,Vitoria M,Doherty M,|

Factors influencing protective behavior in the post-COVID-19 period in China: a cross-s...
https://doi.org/10.1186/s12199-021-01015-2 10.1002/jmv.25748 10.1016/j.amepre.2020.05.004 10.1016/j.envres.2020.109995 10.1016/j.ijid.2020.07.074 10.15585/mmwr.mm6943e4 10.1037/emo0000270 10.1111/j.1468-5914.2008.00363.x 10.1111/j.0272-4332.2004.00531.x 10.1080/026999300402763 10.3389/fpsyg.2020.580053 10.1136/jech.57.11.864 10.1086/429923 10.1080/10410236.2012.708633 10.1037/0003-066X.46.8.819 10.1016/j.jhtm.2021.03.004 10.1016/j.outlook.2020.08.005 10.1037/0022-3514.39.1.13 10.1037/0033-2909.132.5.778 10.1111/disa.12240 10.1016/j.foodres.2020.109518 10.1111/j.1539-6924.2008.01032.x 10.1017/ice.2020.284 10.2196/19782 10.1007/s10865-007-9094-7 10.1371/journal.pntd.0008149 10.1111/j.1539-6924.2012.01942.x 10.1111/bjso.12242 10.2196/19370 10.1111/risa.13675 10.23668/PSYCHARCHIVES.2782 10.1016/j.jenvman.2019.109456 10.3389/fpsyg.2021.647710 10.3386/w27378 10.2307/270754 10.1080/10705519909540118 10.1177/002224378101800104 10.1057/palgrave.rm.8250038 10.1016/j.scs.2020.102626 10.1016/j.jad.2020.06.026 10.1037/0033-295X.86.5.452 10.1371/journal.pone.0237296
Environmental Health and Preventive Medicine; Shi G, Zhong X et. al.

Sep 25th, 2021 - The study aimed to explore the factors influencing protective behavior and its association with factors during the post-COVID-19 period in China based on the risk perception emotion model and the protective action decision model (PADM). A total of 2830 valid questionnaires were collected as data for empirical analysis via network sampling in China. Structural equation modeling (SEM) was perform...

Physical activity and sedentary behaviors (screen time and homework) among overweight o...
https://doi.org/10.1186/s12887-021-02892-w 10.1016/j.puhe.2018.03.019 10.1186/s13104-018-3292-y 10.1016/j.jadohealth.2010.02.016 10.15171/jcvtr.2017.06 10.1111/cch.12701 10.4995/reinad.2020.13236 10.3390/ijerph17217842 10.1016/j.ypmed.2020.106043 10.1186/1753-2000-5-16 10.2471/BLT.07.043497 10.1210/clinem/dgz195 10.1038/s41598-019-56847-4 10.1123/pes.2016-0234 10.1017/S1368980013002218 10.1016/j.ypmed.2020.106349
BMC Pediatrics; Hadianfard AM, Mozaffari-Khosravi H et. al.

Sep 25th, 2021 - The growing number of adolescents who are overweight or obese (OW / OB) is a public concern. The present study was aimed to evaluate physical activity (PA) and sedentary behaviors (SB) (screen time (ST) and homework time (HT)) among Yazd OW/OB adolescents. This cross-sectional study was performed among 510 students aged 12-16 in Yazd, Iran. The general information, PA, and SB (ST and HT) were c...

The risk of COVID-19 in survivors of domestic violence and abuse.
https://doi.org/10.1186/s12916-021-02119-w 10.1016/S2468-2667(20)30112-2 10.1596/33573 10.1016/S0140-6736(21)00532-8 10.1161/JAHA.119.014580 10.1136/bmjopen-2017-020738 10.14236/jhi.v19i4.820 10.1046/J.1365-2532.1994.1130177.X 10.1016/j.jdent.2019.01.008 10.1002/pds.1688 10.1016/S2215-0366(19)30369-4 10.1016/S0140-6736(20)32319-9 10.1136/bmjopen-2020-036949 10.1136/ARCHDISCHILD-2020-319027
BMC Medicine; Chandan JS, Subramanian A et. al.

Sep 25th, 2021 - A 'shadow pandemic' of domestic violence and abuse (DVA) has emerged secondary to strict public health measures containing the spread of SARS-CoV-2. Many countries have implemented policies to allow the free movement of DVA survivors in attempts to minimise their exposure to abusive environments. Although these policies are well received, as a result there is a possibility of increased COVID-19...

How Coronavirus Disease 2019 Changed Dermatology Practice in 1 Year Around the World: P...
https://doi.org/10.1016/j.det.2021.05.014
Dermatologic Clinics; Sun Q, McMahon DE et. al.

Sep 25th, 2021 - Coronavirus disease 2019 (COVID-19) brought the world to its knees. As each nation grappled with launching an effective response while simultaneously minimizing repercussions on health care systems, economies, and societies, the medical and scientific landscape shifted forever. In particular, COVID-19 has challenged and transformed the field of dermatology and the way we practice. In this artic...

Collaboration in times of crisis: A study on COVID-19 vaccine R&D partnerships.
https://doi.org/10.1016/j.vaccine.2021.08.101
Vaccine Druedahl LC, Minssen T et. al.

Sep 25th, 2021 - Collaboration is central for initiatives and efforts in the race to fight COVID-19, with particular focus on fostering rapid development of safe and effective COVID-19 vaccines. We investigated the types of partnerships that have emerged during the pandemic to develop these products. Using the World Health Organization's list of COVID-19 vaccine developments, we found nearly one third of all va...

The underutilized power of independent pharmacies to promote public health in rural com...
https://doi.org/10.1016/j.japh.2021.09.002
Journal of the American Pharmacists Association : JAPhA; Ashcraft AM, Ponte CD et. al.

Sep 25th, 2021 - Independent community pharmacies are in a unique and powerful position to promote public and individual health in their communities. Independent pharmacies are particularly important in rural communities where there are few chain pharmacies and accessible health clinics. West Virginia received national attention recently when they opted out of the Federal Pharmacy Program collaborating with CVS...

Quantitative Analysis of the Olfactory System in COVID-19: An MR Imaging Study.
https://doi.org/10.3174/ajnr.A7278
AJNR. American Journal of Neuroradiology; Altunisik E, Baykan AH et. al.

Sep 25th, 2021 - Anosmia or hyposmia, often accompanied by changes in taste, is recognized as a common symptom that can assist in the diagnosis of coronavirus disease 2019 (COVID-19). The pathogenesis of olfactory dysfunction in COVID-19 is not yet fully understood. MR imaging represents a useful anatomic imaging method for the evaluation of olfactory dysfunction associated with varying etiologies, including vi...

Teaching Video NeuroImages: Uncommon Neuro-ophthalmic Finding in a Patient With Miller-...
https://doi.org/10.1212/WNL.0000000000012859
Neurology Costa AF, Rodríguez A et. al.

Sep 25th, 2021 - Teaching Video NeuroImages: Uncommon Neuro-ophthalmic Finding in a Patient With Miller-Fisher Syndrome and Past SARS-CoV-2 Infection.|2021|Costa AF,Rodríguez A,Martínez P,Blanco MDC,|

Age- and weight group-specific weight gain patterns in children and adolescents during ...
https://doi.org/10.1038/s41366-021-00968-2 10.1111/bjhp.12470 10.1016/j.jaac.2020.05.009 10.1002/oby.22960 10.1002/oby.22861 10.3390/nu12082289 10.1186/s12889-020-09429-3 10.1016/j.pcad.2020.04.013 10.1016/j.orcp.2020.05.004 10.1017/dmp.2020.237 10.1056/NEJMoa1803527 10.1007/s40200-020-00682-2 10.1016/j.jped.2020.07.001 10.1097/MED.0000000000000592 10.1016/j.jpeds.2020.11.016 10.1016/j.jshs.2020.05.006 10.1038/ijo.2015.90 10.1136/bmjopen-2013-003286 10.1038/ijo.2017.6 10.1186/s13104-021-05562-3 10.3390/ijerph18115734 10.1136/bmjpo-2020-000834 10.1007/s001120170107 10.1001/jamapediatrics.2019.2430 10.1017/S1368980017002257 10.1038/s41366-021-00912-4 10.1016/j.numecd.2021.03.018 10.1016/j.eclinm.2021.101026 10.1080/09637486.2018.1492523 10.1136/bmjopen-2015-010978 10.3346/jkms.2021.36.e21 10.3390/children8050404 10.1038/s41366-021-00871-w 10.1038/s41366-020-00710-4 10.3390/nu13030930 10.1186/s12966-017-0555-2 10.1002/oby.21613 10.1002/oby.20977 10.2105/AJPH.2005.080754 10.7326/M20-2665 10.1186/s12966-020-00987-8 10.3389/fped.2020.00573 10.3390/nu12061807 10.1016/j.appet.2021.105132 10.1002/oby.22917 10.3390/nu12061583 10.1016/j.appet.2021.105119
International Journal of Obesity (2005); Vogel M, Geserick M et. al.

Sep 25th, 2021 - There is a concern that measures aiming to limit a further spread of COVID-19, e.g., school closures and social distancing, cause an aggravation of the childhood obesity epidemic. Therefore, we compared BMI trends during the 15 years before and during the COVID-19 pandemic. To assess the change in weight dynamics during the first months of COVID-19, we compared the trends of 3-month change in B...

The embers underneath the CoV-2 pandemic: a semblance of the persistent burn of health ...
https://doi.org/10.1038/s41590-021-01022-z
Nature Immunology; Jones HP, Phillips NR

Sep 25th, 2021 - The embers underneath the CoV-2 pandemic: a semblance of the persistent burn of health inequities and disparities in the United States.|2021|Jones HP,Phillips NR,|

Anecdotes from the pandemic.
https://doi.org/10.1038/s41590-021-01039-4
Nature Immunology;

Sep 25th, 2021 - Anecdotes from the pandemic.|2021||

Associations between Mental Health, Alcohol Consumption and Drinking Motives during COV...
https://doi.org/10.1093/alcalc/agab067
Alcohol and Alcoholism (Oxford, Oxfordshire); Carbia C, García-Cabrerizo R et. al.

Sep 25th, 2021 - The novel coronavirus pandemic (COVID-19) has impacted the lives of people worldwide since March 2020. Social restrictions aimed at flattening the curve may be associated with an increase in mental health problems and have raised concerns regarding their effect on alcohol consumption. The objective of this study was to characterize changes in alcohol use during lockdown in Ireland and associati...

Impact of an Education Intervention on COVID-19 Vaccine Hesitancy in a Military Base Po...
https://doi.org/10.1093/milmed/usab363
Military Medicine; Li PC, Theis SR et. al.

Sep 25th, 2021 - Coronavirus disease 2019 (COVID-19) vaccine hesitancy is a major impediment to achieving herd immunity and overcoming the current pandemic. Our aim was to decrease the prevalence of vaccine hesitancy through an education intervention. An education intervention, consisting of a PowerPoint presentation addressing the two mRNA COVID-19 vaccine concerns/myths and a question and answer panel compris...

Late-presenting Plasmodium falciparum Malaria in a Non-Endemic Setting During COVID-19 ...
https://doi.org/10.1093/milmed/usab393
Military Medicine; Robben PM, Dunbar CR et. al.

Sep 25th, 2021 - We report a case of febrile Plasmodium falciparum malaria in a 36-year-old male patient occurring 14 years after immigration from and more than 12 months since a return visit to the endemic area. The critical need for awareness regarding late presentations of P. falciparum is discussed.

WIC Participants' Perceptions of COVID-19-Related Changes to WIC Recertification and Se...
https://doi.org/10.1007/s10900-021-01026-8 10.1007/s10995-013-1281-2 10.1111/phn.12259 10.1016/j.jand.2021.05.003 10.1016/j.jada.2004.02.028 10.1016/j.evalprogplan.2017.03.002 10.17226/10804 10.2105/ajph.2021.306211 10.1002/pam.20070 10.1007/s11293-011-9294-y 10.1016/s1499-4046(06)60171-1 10.1016/0002-8223(97)00191-0 10.1016/j.jand.2018.09.003 10.1016/j.jneb.2019.12.006
Journal of Community Health; Ventura AK, Martinez CE et. al.

Sep 25th, 2021 - Many Special Supplemental Nutrition Program for Women, Infants, and Children (WIC) clinics implemented alternatives to in-person service delivery in response to the COVID-19 pandemic, including virtual visits and electronic document sharing. The objective of this cross-sectional study was to describe WIC participants' experiences with remote service delivery and recertification during the pande...

Combination therapies for COVID-19: an overview of the clinical trials landscape.
https://doi.org/10.1111/bcp.15089
British Journal of Clinical Pharmacology; Akinbolade S, Coughlan D et. al.

Sep 25th, 2021 - The COVID-19 pandemic has driven an unprecedented level of global activity in drug discovery and clinical development for effective therapeutics targeting the coronavirus disease. There are currently 744 therapeutics being tested in 2879 clinical trials globally. Almost 90% of these clinical trials are focused on monotherapies. Combination therapies are the mainstay of antiviral therapeutics to...

Excess Mortality in Solid Organ Transplant Recipients Hospitalized with COVID-19: A Lar...
https://doi.org/10.1111/ctr.14492
Clinical Transplantation; Jering KS, McGrath MM et. al.

Sep 25th, 2021 - Solid-organ transplant (SOT) recipients with COVID-19 have higher risk of adverse outcomes compared to the general population. Whether hospitalized SOT recipients with COVID-19 are at higher risk of mortality than SOT recipients hospitalized for other causes, including non-COVID-19 pneumonia, remains unclear. We used logistic regression to compare outcomes of SOT recipients hospitalized with CO...

Virtual support groups in pediatric hematology/oncology during COVID-19: Lessons learne...
https://doi.org/10.1002/pbc.29378
Pediatric Blood & Cancer; Kaka A, Shama W et. al.

Sep 25th, 2021 - Virtual support groups in pediatric hematology/oncology during COVID-19: Lessons learned from the SickKids experience.|2021|Kaka A,Shama W,Lucchetta S,Nishimura C,Cottingham D,|

Preliminary Efficacy and Acceptability of an Online Exercise and Nutrition Workplace We...
https://doi.org/10.1177/21650799211037528
Workplace Health & Safety; SantaBarbara N, Rezai R et. al.

Sep 25th, 2021 - Workplace wellness programs (WWP) offer physiological and psychological benefits to employees and financial and productivity benefits to employers. However, the COVID-19 pandemic has prevented in-person sessions and has required WWP's to transition to online platforms. The purpose of this brief report was to assess the preliminary feasibility, acceptability, and efficacy of a mobile version of ...

Assessing the fear of COVID-19 scale among health care workers in Israel: a psychometri...
https://doi.org/10.1080/07481187.2021.1975175
Death Studies; Hawley CE, Iwanaga K et. al.

Sep 25th, 2021 - We explored the psychometric properties of the Hebrew version of the Fear of COVID-19 (FCV-19S) scale among health care workers in a large medical center in Israel. Participants (N = 705) completed the FCV-19S scale, as well as resilience, subjective well-being, and meaning in life using validated scales. Results showed a two-factor structural model accounting for 79.33% of the total variance. ...

Efficacy and secondary infection risk of tocilizumab, sarilumab and anakinra in COVID-1...
https://doi.org/10.1002/rmv.2295
Reviews in Medical Virology; Peng J, Fu M et. al.

Sep 25th, 2021 - As the pandemic progresses, the pathophysiology of coronavirus disease 2019 (COVID-19) is becoming clearer and the potential for immunotherapy is increasing. However, clinical efficacy and safety of immunosuppressants (including tocilizumab, sarilumab and anakinra) treatment in COVID-19 patients are not yet known. We searched PubMed, Embase Medline, Web of Science and MedRxiv using specific sea...

Genetic counseling in the time of COVID-19: The Philippine experience with telegenetics.
https://doi.org/10.1002/jgc4.1518
Journal of Genetic Counseling; Tumulak MJR, Pascua AV et. al.

Sep 25th, 2021 - The COVID-19 pandemic poses a significant challenge to healthcare professionals and health systems around the world, most notably the disruption of its service delivery. The typical work setting for most genetic counselors (GCs) is in a clinic or hospital. However, during the COVID-19 pandemic, to help prevent the further spread of the virus, clinics and hospitals have restricted non-urgent in-...

The role of the cord blood platelet gel in the management of a diabetic foot with tendo...
https://doi.org/10.2217/rme-2021-0044
Regenerative Medicine; Massara M, Pucci G et. al.

Sep 25th, 2021 - Diabetic foot infection is frequent in diabetic patients and is due to neuropathy, trauma or peripheral arterial disease. The presence of an abscess requires urgent drainage and specific antibiotic therapy. Patients with critical limb ischemia need revascularization and, subsequently the intervention of a plastic surgeon is often required in cases of exposure of tendons and ligaments. During th...

Birth Satisfaction During the Early Months of the COVID-19 Pandemic in the United States.
https://doi.org/10.1097/NMC.0000000000000777
MCN. The American Journal of Maternal Child Nursing; Mollard E, Kupzyk K

Sep 25th, 2021 - Purpose: The purpose of this study was to describe birth satisfaction in women who gave birth in U.S. hospitals during the earliest months of the COVID-19 pandemic (March-July 2020).Study Design and Methods: A cross-sectional survey of 747 postpartum women who gave birth in the United States during the early COVID-19 pandemic was conducted. Participants in the United were recruited via social m...

Limited Protection of Inactivated SARS-CoV-2 Vaccine against Wuhan Strain and Variants ...
https://doi.org/10.3201/eid2712.211772
Emerging Infectious Diseases; Hunsawong T, Fernandez S et. al.

Sep 25th, 2021 - In vitro determination of severe acute respiratory syndrome coronavirus 2 neutralizing antibodies induced in serum samples from recipients of the CoronaVac vaccine showed a short protection period against the original virus strain and limited protection against variants of concern. These data provide support for vaccine boosters, especially variants of concern circulate.

Computed tomography features of COVID-19 in children: A systematic review and meta-anal...
https://doi.org/10.1097/MD.0000000000022571 10.1093/tropej/fmaa045
Medicine Wang JG, Mo YF et. al.

Sep 25th, 2021 - There are few reports on the chest computed tomography (CT) imaging features of children with coronavirus disease 2019 (COVID-19), and most reports involve small sample sizes. To systematically analyze the chest CT imaging features of children with COVID-19 and provide references for clinical practice. We searched PubMed, Web of Science, and Embase; data published by Johns Hopkins University; a...

Trajectory of COVID-19 Vaccine Hesitancy Over Time and Association of Initial Vaccine H...
https://doi.org/10.1001/jamanetworkopen.2021.26882
JAMA Network Open; Siegler AJ, Luisi N et. al.

Sep 25th, 2021 - Trajectory of COVID-19 Vaccine Hesitancy Over Time and Association of Initial Vaccine Hesitancy With Subsequent Vaccination.|2021|Siegler AJ,Luisi N,Hall EW,Bradley H,Sanchez T,|

Addressing COVID-19 Vaccine Hesitancy in Patients with IBD.
https://doi.org/10.1093/ibd/izab241
Inflammatory Bowel Diseases; Hudhud D, Caldera F et. al.

Sep 25th, 2021 - Addressing COVID-19 Vaccine Hesitancy in Patients with IBD.|2021|Hudhud D,Caldera F,Cross RK,|

The impact of COVID-19 pandemic on the rate of newly diagnosed gynecological and breast...
https://doi.org/10.1007/s00404-021-06259-5 10.1136/ijgc-2020-001975 10.1002/cncr.33274 10.1200/CCI.20.00134 10.1016/S2468-1253(21)00017-0 10.1001/jamaoncol.2020.7600 10.3389/fpubh.2020.601748 10.1001/jamanetworkopen.2020.17267.) 10.1097/CEJ.0000000000000686 10.1136/ijgc-2020-001942 10.1136/ijgc-2020-001634 10.3390/cancers12041053
Archives of Gynecology and Obstetrics; Knoll K, Reiser E et. al.

Sep 25th, 2021 - The aim of the present study was to assess the impact of postponed screening examinations and lockdown measures on gynecological and breast cancer diagnoses throughout the year 2020 in a gynecological oncological center in Austria. Data of 889 patients with either newly diagnosed gynecological or breast cancer between January 2019 and December 2020 were collected. Clinical parameters including ...

Extending the Common Sense Model to Explore the Impact of the Fear of COVID-19 on Quali...
https://doi.org/10.1007/s10880-021-09823-y 10.1007/s11469-020-00270-8 10.4103/sjmms.sjmms_630_20 10.1007/s11469-020-00331-y 10.1016/S2468-1253(21)00014-5 10.1111/eci.13233 10.1016/j.jpsychores.2005.10.020 10.1207/s15327558ijbm0401_6 10.1037/0022-3514.56.2.267 10.1136/bmjgast-2020-000581 10.1016/j.cgh.2021.02.004 10.1016/S2468-1253(20)30151-5 10.1002/ibd.20583 10.1097/MIB.0000000000000856 10.1093/ecco-jcc/jjaa126 10.1037/bul0000118 10.1007/s11469-020-00281-5 10.1016/j.jpsychores.2020.110283 10.1080/10705519909540118 10.1002/ibd.21215 10.12688/wellcomeopenres.15870.2 10.1016/j.crohns.2013.02.022 10.1093/ibd/izx100 10.1002/ibd.21650 10.1016/j.invent.2020.100345 10.1016/j.crohns.2012.05.021 10.1097/MIB.0000000000000476 10.1016/j.janxdis.2020.102258 10.1097/MIB.0000000000000620 10.4103/sjg.SJG_220_20 10.1177/0020764020925835 10.1007/s11469-020-00356-3 10.1186/s12992-020-00624-w 10.1007/s11469-020-00294-0 10.1093/eurpub/cki155 10.1093/ibd/izaa196 10.1097/MIB.0000000000001040 10.1007/BF01535722 10.1093/ibd/izaa261 10.1093/ecco-jcc/jju025 10.1016/j.crohns.2012.11.002 10.1007/s12529-016-9599-y 10.2147/PPA.S118413 10.2196/19574
Journal of Clinical Psychology in Medical Settings; Hayes B, Apputhurai P et. al.

Sep 25th, 2021 - The aim of this cross-sectional study was to use an extended common sense model (CSM) to evaluate the impact of fear of COVID-19 on quality of life (QoL) in an international inflammatory bowel disease cohort. An online study involving 319 adults (75% female, mean (SD) 14.06 (15.57) years of symptoms) completed the Gastrointestinal Symptom Rating Scale, Brief Illness Perceptions Questionnaire, F...

Social environmental impact of COVID-19 and erectile dysfunction: an explorative review.
https://doi.org/10.1007/s40618-021-01679-1 10.3390/ijerph17082690 10.1080/13548506.2021.1916963 10.1016/j.esxm.2018.11.001 10.1007/s10508-019-1443-4 10.1016/j.jsxm.2020.05.001 10.1177/1557988319892464 10.1371/journal.pmed.1000100 10.1001/jama.283.15.2008 10.1016/0197-2456(86)90046-2 10.1002/sim.1186 10.1136/bmj.315.7109.629 10.1111/j.0006-341X.2000.00455.x 10.1111/and.13971 10.1038/s41443-020-00381-9 10.1016/j.esxm.2020.100293 10.1016/j.jsxm.2020.10.008 10.1016/j.esxm.2020.100295 10.1016/j.jsxm.2016.01.019 10.1086/508824
Journal of Endocrinological Investigation; Pizzol D, Shin JI et. al.

Sep 25th, 2021 - To date, no attempt has been made to collate literature on the relationship between the social environmental impact of COVID-19 and erectile dysfunction. The aim of this explorative review was to assess and compare the prevalence of erectile dysfunction (ED) in male healthcare workers and males during the COVID-19 pandemic. A systematic review of major databases from inception to February 2021 ...

Collapsing glomerulopathy in a patient with APOL1 intermediate-risk genotype triggered ...
https://doi.org/10.1007/s40620-021-01144-5 10.1038/ki.1994.185 10.2215/CJN.11751111 10.1016/j.kint.2020.04.006 10.2215/CJN.06720615 10.1681/ASN.2012121180 10.1681/ASN.2020050699 10.1681/ASN.2020060804 10.1038/s41581-020-0332-3 10.1038/ki.2014.270
Journal of Nephrology; Masset C, Renaudin K et. al.

Sep 25th, 2021 - Collapsing glomerulopathy in a patient with APOL1 intermediate-risk genotype triggered by lupus nephritis and SARS-CoV-2 infection: lessons for the clinical nephrologist.|2021|Masset C,Renaudin K,Kervella D,Chapelet A,Deltombe C,|

Do High Dose Corticosteroids Improve Outcomes in Hospitalized COVID-19 Patients?
https://doi.org/10.1002/jmv.27357
Journal of Medical Virology; Kumar G, Patel D et. al.

Sep 25th, 2021 - COVID-19 is characterized by dysregulated hyperimmune response and steroids have been shown to decrease mortality. However, whether higher dosing of steroids results in better outcomes have been debated. This was a retrospective observational of COVID-19 admissions between March 1st 2020 and March 10th 2021. Adult patients (≥18 years) who received more than 10mg daily methylprednisolone equival...

Clinical features of Chinese children with COVID-19 and other viral respiratory infecti...
https://doi.org/10.1002/ppul.25700
Pediatric Pulmonology; Zhang ZZ, Chen DP et. al.

Sep 25th, 2021 - Few studies have explored the clinical features in children infected with SARS-CoV-2 and other common respiratory viruses, including respiratory syncytial virus (RSV), influenza virus (IV), and adenovirus (ADV). Herein, we reported the clinical characteristics and cytokine profiling in children with COVID-19 or other acute respiratory tract infections (ARTI). We enrolled 20 hospitalized childre...

Perinatal Planning Guide: Mitigating Perinatal Mood and Anxiety Disorders During the CO...
https://doi.org/10.4088/PCC.21nr02953
The Primary Care Companion for CNS Disorders; Susser LC, Wilkins VM et. al.

Sep 25th, 2021 - Women are at high risk for and more vulnerable to perinatal mood and anxiety disorders (PMADs) during the coronavirus disease 2019 (COVID-19) pandemic. While access to specialized perinatal mental health services is limited, clinicians with whom women have ongoing relationships are in a unique position to counsel about prevention of PMADs. These clinicians include primary care, obstetric, and g...

FDA Issues Orders Clarifying Rules for Marketing Sunscreens
https://www.medpagetoday.com/dermatology/skincancer/94712

Sep 24th, 2021 - WASHINGTON -- The FDA on Friday issued two orders officials say are aimed at making sunscreens safer and clarifying requirements regarding active ingredients, although for now there won't be any noticeable effect on which sunscreen products consumers see on retail shelves. "Americans can reduce risks from sun exposure with continued use of sun protection measures, including broad-spectrum sunsc...

Another MS Drug Class Causes Concern for COVID Vaccine Protection
https://www.medpagetoday.com/neurology/multiplesclerosis/94711

Sep 24th, 2021 - Multiple sclerosis (MS) patients treated with cladribine (Mavenclad) or teriflunomide (Aubagio) had appropriate humoral response against SARS-CoV-2 a month after vaccination, but those treated with anti-CD20 therapies or sphingosine-1-phosphate receptor (S1P) modulators did not, a Swiss study showed. Of 120 MS patients at the Neurocenter of Southern Switzerland who received either the Moderna o...

Walensky: Pfizer Boosters for High-Risk Workers a 'Scientific Close Call'
https://www.medpagetoday.com/infectiousdisease/covid19vaccine/94710

Sep 24th, 2021 - Recommending Pfizer vaccine (Comirnaty) booster doses for adults at high occupational risk of COVID-19 exposure based on individual risk was not a decision that CDC Director Rochelle Walensky, MD, came to lightly. In a press briefing on Friday, Walensky described her decision as a "scientific close call," and reiterated that she listened to not only the CDC's Advisory Committee on Immunization ...

How Many Deaths Will New Cigarette Warnings Prevent?
https://www.medpagetoday.com/primarycare/smoking/94694

Sep 24th, 2021 - Assuming they survive an ongoing legal challenge and are as effective as advocates hope, the new graphic warnings to appear on cigarette packages beginning next year could prevent millions of deaths from smoking over the following 8 decades, researchers estimated. Modeling by Rafael Meza, PhD, of the University of Michigan in Ann Arbor, and colleagues indicated that, depending on the degree to ...

CDC Overrules Advisors on Pfizer Booster for High-Risk Workers
https://www.medpagetoday.com/infectiousdisease/covid19vaccine/94692

Sep 24th, 2021 - In a rare move, CDC overruled the recommendations of the agency's Advisory Committee on Immunization Practices (ACIP) regarding who should get a booster of Pfizer's COVID-19 vaccine (Comirnaty). In a statement released early Friday, the agency said those at high risk of occupational exposure, such as healthcare workers, may receive the Pfizer booster shot at least 6 months after the two-dose pr...

Warning on Tylenol in Pregnancy; Multi-Dose Vial Flaw; Angiographic Catheter Recall
https://www.medpagetoday.com/infectiousdisease/covid19/94691

Sep 24th, 2021 - Note that some links may require registration or subscription. A consensus statement from more than 100 scientists and clinicians warned about the possible fetal development dangers of prenatal exposure to acetaminophen. (Nature Reviews Endocrinology) Does new Florida Surgeon General Joseph Ladapo, MD, PhD, have ties to controversial America's Frontline Doctors? (Slate) In other Florida news, a...

In a Year of Change, Young Doc Salaries Remain the Same: Survey
https://www.medscape.com/viewarticle/959647

Sep 24th, 2021 - Because of the COVID-19 pandemic, physicians younger than 40 faced uncertainty regarding physician office closures, the treating of patients with and those without the virus, and the possibility of contracting the virus themselves. But financially speaking, young physicians landed on their feet, according to a new report. Young primary care physicians took home $242,000 in 2020, while their spe...

Extension Study Finds Dupilumab Effective for Up To 1 Year in Teens With AD
https://www.medscape.com/viewarticle/959696

Sep 24th, 2021 - Serious adverse events remained rare and skin remained largely clear in adolescents treated with dupilumab (Dupixent) for moderate-to-severe atopic dermatitis (AD) for up to 52 weeks in a phase 3 open-label extension trial, researchers reported. At 1 year, 86% of 50 remaining patients with weights under 60 kg (132 lb) had achieved 75% improvement (EASI-75; Eczema Area and Severity Index), and 7...

Two COVID-19 Vaccine Scientists Win 2021 Lasker Award in Medicine
https://www.medscape.com/viewarticle/959721

Sep 24th, 2021 - Editor's note: Find the latest COVID-19 news and guidance in Medscape's Coronavirus Resource Center. Katalin Kariko, PhD, a senior vice president at BioNTech, and Drew Weissman, MD, PhD, a professor in vaccine research at the University of Pennsylvania, Philadelphia, Pennsylvania, made a breakthrough discovery by modifying messenger RNA (mRNA), which provides instructions to cells to make prote...

FDA Issues Proposed Order for Over-the-Counter Sunscreens
https://www.medscape.com/viewarticle/959728

Sep 24th, 2021 - Federal efforts to improve the quality, safety, and efficacy of over-the-counter sunscreens took a step forward today with the release of two orders aimed at updating regulatory requirements for most sunscreen products in the United States. "We see it as a key public health priority and our regulatory obligation to make sure that marketed sunscreen products offer protection from the sun's effec...