Jan 16th, 2021 - The significance of chronic kidney disease on susceptibility to COVID-19 and subsequent outcomes remains unaddressed. To investigate the association of eGFR on risk of contracting COVID-19 and subsequent adverse outcomes. Rates of hospital-diagnosed COVID-19 were compared across strata of eGFR based on conditional logistic regression using a nested case-control framework with 1:4 matching of pa...

Jan 16th, 2021 - To report changes in practice brought about by COVID-19 and the implementation of new guidelines, and to explore factors relating to unscheduled re-presentations for patients discharged from the emergency department (ED). Prospective multicentre national audit over 12 weeks from 6th April 2020. UK secondary care ENT departments. Adult patients with acute epistaxis. Re-presentation within 10 day...

Jan 16th, 2021 - There is limited data on the characteristics of 30-day readmission after hospitalization with coronavirus disease 2019 (COVID-19). To examine the rate, timing, causes, predictors, and outcomes of 30-day readmission after COVID-19 hospitalization. From March 13 to April 9, 2020, all patients hospitalized with COVID-19 and discharged alive were included in this retrospective observational study. ...

Jan 16th, 2021 - In March 2020, a state of emergency was declared to facilitate organized responses to the coronavirus disease 2019 (COVID-19) pandemic in British Columbia, Canada. Emergency blood management committees (EBMCs) were formed regionally and provincially to coordinate transfusion service activities and responses to possible national blood shortages. We describe the responses of transfusion services ...

Jan 16th, 2021 - In March 2020, the Food and Drug Administration (FDA) approved use of COVID-19 convalescent plasma (CCP) as an investigational new drug for treatment of COVID-19. Since then, collection of CCP from COVID-19-recovered patients has been implemented in donor centers nationwide. Children's Hospital Colorado rapidly put into practice a CCP collection protocol, necessitating development and implement...

Jan 16th, 2021 - There are limited data on the impact of COVID-19 in children with a kidney transplant. We conducted a prospective cohort study through the Improving Renal Outcomes Collaborative (IROC) to collect clinical outcomes data about COVID-19 in pediatric kidney transplant patients. Twenty-two IROC centers that care for 2732 patients submitted testing and outcomes data for 281 patients tested for SARS-C...

Jan 16th, 2021 - Speech disturbance plays critical role in stroke recognition during COVID-19 pandemic.|2021|Liu R,Fisher M,Rudd A,Zhao J,|

Jan 16th, 2021 - In Italy, colorectal surgery has been strongly affected with the vast majority (90%) of operations treating benign diseases, with an estimated overall 12-week cancellation rate of 72%. Little is known on how to best manage patients with benign diseases and the consequences this interruption of care will have in post-pandemic times. Proctologic diseases have social, psychological, and healthcare...

Jan 16th, 2021 - While telemedicine usage has increased due to the COVID-19 pandemic, there remains little consensus about how spine surgeons perceive virtual care. The purpose of this study was to explore international perspectives of spine providers on the challenges and benefits of telemedicine. Responses from 485 members of AO Spine were analyzed, covering provider perceptions of the challenges and benefits...

Jan 16th, 2021 - The COVID-19 pandemic forced many surgeons to adopt "virtual medicine" practices, defined as telehealth services for patient care and online platforms for continuing medical education. The purpose of this study was to assess spine surgeon reliance on virtual medicine during the pandemic and to discuss the future of virtual medicine in spine surgery. A comprehensive survey addressing demographic...

Jan 16th, 2021 - COVID 19 pandemic has posed challenges for public mental healthcare delivery, particularly in LAMI countries such as India. However, this unique situation has also brought in opportunities to revisit the health system and optimally utilize the available resources. In this brief report, we report one such new initiative in which existing community health workers (CHWs), known as ASHAs (Accredite...

Jan 16th, 2021 - SARS-CoV2-induced direct cytopathic effects against type II pneumocytes are suspected to play a role in mediating and perpetuating lung damage. The aim of this study was to evaluate serum KL-6 behavior in COVID-19 patients to investigate its potential role in predicting clinical course. Sixty patients (median age IQR, 65 (52-69), 43 males), hospitalized for COVID-19 at Siena COVID Unit Universi...

Jan 16th, 2021 - Coronavirus disease 2019 (COVID-19) is an emerging infectious disease which has had a rapid surge in cases and deaths since it is first documented in Wuhan, China, in December 2019. COVID-19 is caused by the Betacoronavirus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). SARS-CoV-2 uses angiotensin-converting enzyme 2, which is highly expressed in the human lower respiratory tract...

Jan 16th, 2021 - The COVID-19 pandemic has led to increased staffing needs in emergency departments. The question quickly arose as to whether it was appropriate to offer medical students the opportunity to assist this staff. The dilemma stems in part from the potential impact on their psychological well-being as well as their academic and clinical performances. We sought to determine the level of anxiety of med...

Jan 16th, 2021 - Immunocompromised populations are at great risk of the current 2020 global emergency of coronavirus disease 2019 (COVID-19), and treatment of kidney transplant recipients with COVID-19 is currently not declared. Hence, the purpose of the study is to set a clear treatment regimen. We report here a therapeutic course of 2 patients who underwent transplant surgery in March 2020 and got infected so...

Jan 16th, 2021 - In liver transplant (LT) recipients with severe coronavirus disease 2019 (COVID-19), fatal outcome has been reported in a substantial subset of patients. Whether LT recipients are at increased risk for severe COVID-19 compared with the general population is controversial. Here we report the results of a severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) serosurvey in a large LT recipi...

Jan 16th, 2021 - COVID-19 narratives from the New York Roentgen Society.|2021|Nwawka OK,Katzen JT,|

Jan 16th, 2021 - As the novel severe acute respiratory syndrome coronavirus-2 related pandemic - Corona Virus Disease 2019 (COVID-19) has emerged, decision making in the context of cancer treatment has become more complex. The apprehension of using drugs that could adversely affect infected patients, the risk of not using life-saving treatments and the complexities related to the type of cancer itself, all must...

Jan 16th, 2021 - Covid-19: Norway investigates 23 deaths in frail elderly patients after vaccination.|2021|Torjesen I,|

Jan 16th, 2021 - Covid-19: Japan declares second state of emergency as Asia struggles with virus surge.|2021|Looi MK,|

Jan 16th, 2021 - To determine the indirect consequences of the COVID-19 pandemic on paediatric healthcare utilisation and severe disease at a national level following lockdown on 23 March 2020. National retrospective cohort study. Emergency childhood primary and secondary care providers across Scotland; two national paediatric intensive care units (PICUs); statutory death records. 273 455 unscheduled primary ca...

Jan 16th, 2021 - Response to: 'Correspondence on 'Prevalence and clinical outcomes of COVID-19 in patients with autoimmune diseases: a systematic review and meta-analysis'' by Yang et al.|2021|Akiyama S,Hamdeh S,Micic D,Sakuraba A,|

Jan 16th, 2021 - The immunomodulatory effects of immune checkpoint blockade (ICB) therapy for cancer may act at the crossroads between the need to increase anti-viral immune responses to severe acute respiratory syndrome coronavirus 2 (SARS-CoV2) and to decrease the inflammatory responses in severe cases of coronavirus disease 2019 (COVID-19). There is evidence from preclinical models that blocking programmed d...

Jan 16th, 2021 - Covid-19: Doctors' leaders call for revised PPE guidance to reflect new variants.|2021|Iacobucci G,|

Jan 16th, 2021 - Covid-19: Government uses lateral flow tests to keep children in schools against regulator's advice.|2021|Wise J,|

Jan 16th, 2021 - Emergency Medicine Journal COVID-19 monthly top five.|2021|Horner D,O'Rourke J,Collins J,Darbyshire D,Lecky F,|

Jan 16th, 2021 - A 53-year-old man with diabetes came to the emergency department with fever and dry cough for 5 days, swelling of the left leg for 2 days, shortness of breath and chest pain for 1 hour. He had raised temperature, tachycardia, tachypnoea, reduced oxygen saturation and swollen tender left leg on examination. The frontal chest radiograph showed bilateral ground-glass opacities; he tested positive ...

Jan 16th, 2021 - The goals of this review are to evaluate the impact of socioeconomic (SE) status on the general health and cardiovascular health of individuals during the COVID-19 pandemic and also discuss the measures to address disparity. SE status is a strong predictor of premature morbidity and mortality within general health. A lower SE status also has implications of increased cardiovascular disease (CVD...

Jan 16th, 2021 - The quality of healthcare service websites gains particular importance in the time of the pandemic, asthe popularity of electronic services grows. This applies to infectious disease hospitals as well, often on the front line of the effort against COVID-19. The paper aims to assess the quality of infectious disease hospital websites in Poland in light of the COVID-19 pandemic. The research cover...

Jan 16th, 2021 - An EUA for casirivimab and imdevimab for COVID-19.|2021||

Jan 16th, 2021 - An EUA for baricitinib (Olumiant) for COVID-19.|2021||

Jan 16th, 2021 - COVID-19 caused some worries among pregnant women. Worries during pregnancy can affect women's well-being. We investigated worry and well-being and associated factors among pregnant women during the COVID-19 pandemic. This descriptive cross-sectional study was conducted on 484 pregnant women using an online questionnaire. Sampling was performed in a period between May 5 and Aug 5, 2020. Inclusi...

Jan 16th, 2021 - The actual SARS-CoV-2 outbreak caused a highly transmissible disease with a tremendous impact on elderly people. So far, few studies focused on very elderly patients (over 80 years old). In this study we examined the clinical presentation and the outcome of the disease in this group of patients, admitted to our Hospital in Rome. This is a single-center, retrospective study performed in the Sant...

Jan 16th, 2021 - COVID19 is a respiratory disease caused by a novel coronavirus. As there has been no definitive treatment for the disease so far, the only way to control the spread is to break the chain of infection. Our study aimed to analyze the preventive behaviors and influencing factors in the Iranian population. This cross-sectional study was a web-based survey in the Iranian population. We performed the...

Jan 16th, 2021 - The relationship between socioeconomic status and the risk of contracting coronavirus disease (COVID-19) remains controversial. We aimed to investigate whether socioeconomic status affected the risk of contracting COVID-19 in the South Korean population. The NHIS-COVID-19 database cohort was used in this population-based study. We collected the data of COVID-19 patients who were diagnosed betwe...

Jan 16th, 2021 - Mental health care systems have been dramatically affected by COVID-19. Containment measures have been imposed, with negative consequences on population mental health. Therefore, an increase in both symptomatology and mental disorder incidence is expected. This research aims to identify, describe and assess the empirical background on online strategies and recommendations developed by internati...

Jan 16th, 2021 - Some studies investigated epidemiological and clinical features of laboratory-confirmed patients with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) the virus causing coronavirus disease 2019 (COVID-19), but limited attention has been paid to the follow-up of hospitalized patients on the basis of clinical setting and the expertise of clinical management. In the present single-cent...

Jan 16th, 2021 - Hyperreflective lesions at the level of ganglion cell (GCL) and inner plexiform retinal layers (IPL) by optical coherence tomography (OCT) and cotton wool spots in the examination of the eye fundus have recently been described as findings in patients with COVID-19 infection. We report the case of a 42-year-old healthy Caucasian male anesthetist who had treated COVID-19 patients during the previ...

Jan 16th, 2021 - COVID-19 Pandemic and the Need for Disaster Planning in Surgical Education.|2021|Ellison EC,Shabahang MM,|

Jan 16th, 2021 - COVID-19 and Firearm Injury: A Uniquely American Problem.|2021|Sarani B,|

Jan 16th, 2021 - The COVID-19 pandemic could increase violence against children at home. However, collecting empirical data on violence is challenging due to ethical, safety, and data quality concerns. This study estimated the anticipated effect of COVID-19 on violent discipline at home using multivariable predictive regression models. Children aged 1-14 years and household members from the Multiple Indicator C...

Jan 16th, 2021 - During the COVID-19 pandemic, healthcare workers (HCW) have been exposed to multiple psychosocial stressors. Resilience might protect employees from the negative consequences of chronic stress. The aim of this study was to explore the mediating role of resilience in the relationship between depression and burnout (personal, work-related, and client-related). A cross-sectional study was performe...

Jan 16th, 2021 - This meta-analysis aimed to evaluate the prognostic performance of elevated lactate dehydrogenase (LDH) in patients with COVID-19. A systematic literature search was performed using PubMed, Embase and EuropePMC on 19 November 2020. The outcome of interest was composite poor outcome, defined as a combined endpoint of mortality, severity, need for invasive mechanical ventilation and need for inte...

Jan 16th, 2021 - The COVID-19 pandemic has disrupted education-related activities, including the conduct of examinations. We review the literature regarding high-stakes examinations during the pandemic, discuss the decision-making process of whether to proceed with a high-stakes examination and share published experiences in conducting high-stakes examinations during the pandemic. We illustrate our own recent e...

Jan 16th, 2021 - COVID-19: an ethical predicament and the dichotomy of society.|2021|Talwar HS,Narain TA,|

Jan 16th, 2021 - Vitamin D and COVID-19: causal factor or bystander?|2021|Cheung CL,Cheung BMY,|

Jan 16th, 2021 - Relatively limited data are available regarding paediatric COVID-19. Although most children appear to have mild or asymptomatic infections, infants and those with comorbidities are at increased risk of experiencing more severe illness and requiring hospitalisation due to COVID-19. The recent but uncommon association of SARS-CoV-2 infection with development of a multisystem inflammatory syndrome...

Jan 16th, 2021 - The outbreak of COVID-19 caused by SARS-CoV-2 has resulted in more than 50 million confirmed cases and over 1 million deaths worldwide as of November 2020. Currently, there are no effective antivirals approved by the Food and Drug Administration to contain this pandemic except the antiviral agent remdesivir. In addition, the trimeric spike protein on the viral surface is highly glycosylated and...

Jan 16th, 2021 - To determine whether the IntelliVue monitor (ECG plus Masimo pulse oximeter (PO)) displays heart rate (HR) at birth more quickly than Nellcor PO (PO alone) among infants of 29-35 weeks' gestational age. Unmasked parallel group randomised (1:1) study. We planned to enrol 100 infants; however, the study was terminated due to the COVID-19 pandemic when 39 infants had been enrolled (17 randomised t...

Jan 16th, 2021 - 2020 FDA approvals: momentum kept despite COVID-19, but value falls.|2021|Baedeker M,Ringel M,Schulze U,|