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Placental Injury Reported in Women With COVID-19
https://www.medscape.com/viewarticle/931355

May 28th, 2020 - Editor's note: Find the latest COVID-19 news and guidance in Medscape's Coronavirus Resource Center. Maternal vascular malperfusion and intervillous thrombi were more common in the placentas of women infected with SARS-CoV-2, compared with historic controls, report researchers who conducted the first-of-its-kind case series in the English literature. Nevertheless, the neonates in the report app...

SARS-CoV-2 Infection Rate 16% in Asymptomatic Pregnant Women at Delivery
https://www.medscape.com/viewarticle/931356

May 28th, 2020 - Editor's note: Find the latest COVID-19 news and guidance in Medscape's Coronavirus Resource Center. Among women with a planned delivery in a New York City health system during the first half of April, the rate of asymptomatic SARS-CoV-2 infection was 16%, according to a study published in Obstetrics & Gynecology. Among the patients' designated support persons, the asymptomatic carrier rate was...

Whether to Test Laboring Women for Sars-Cov-2 May Hinge on Regional Prevalence
https://www.medscape.com/viewarticle/931357

May 28th, 2020 - Editor's note: Find the latest COVID-19 news and guidance in Medscape's Coronavirus Resource Center. Labor & delivery units may need to consider regional prevalence of COVID-19 when deciding whether to test asymptomatic pregnant women for SARS-CoV-2 infection at the time of admission, research published online in Obstetrics & Gynecology suggests. In Los Angeles, researchers stopped universal te...

Coronavirus Map: Tracking the Global Outbreak
https://www.nytimes.com/interactive/2020/world/coronavirus-maps.html
New York Times;

May 28th, 2020 - The coronavirus pandemic has sickened more than 5,810,200 people, according to official counts. As of Friday morning, at least 360,400 people have died, and the virus has been detected in nearly every country, as these maps show.

Coronavirus (COVID-19) Update: Daily Roundup May 28, 2020 | FDA
https://www.fda.gov/news-events/press-announcements/coronavirus-covid-19-update-daily-roundup-may-28-2020

May 28th, 2020 - For Immediate Release: May 28, 2020 The U.S. Food and Drug Administration today announced the following actions taken in its ongoing response effort to the COVID-19 pandemic: The FDA issued an Emergency Use Authorization for the Stryker Sustainability Solutions (SSS) VHP N95 Respirator Decontamination System (RDS). This product uses vapor hydrogen peroxide (VHP) to decontaminate compatible N95 ...

Any unique image biomarkers associated with COVID-19?
https://doi.org/10.1007/s00330-020-06956-w
European Radiology; Pu J, Leader J et. al.

May 27th, 2020 - To define the uniqueness of chest CT infiltrative features associated with COVID-19 image characteristics as potential diagnostic biomarkers. We retrospectively collected chest CT exams including n = 498 on 151 unique patients RT-PCR positive for COVID-19 and n = 497 unique patients with community-acquired pneumonia (CAP). Both COVID-19 and CAP image sets were partitioned into three groups for ...

Guidance for Resumption of Routine Electrodiagnostic Testing during the COVID-19 Pandemic.
https://doi.org/10.1002/mus.26990
Muscle & Nerve; Desai U, Kassardjian CD et. al.

May 27th, 2020 - As the world accommodates to the COVID-19 pandemic, routine in-person medical services are resuming. The resumption of non-urgent electrodiagnostic (EDX) testing faces unique challenges due to the long duration of the procedure and direct close contact with patients, including studies with risk of exposure to oropharyngeal secretions. We provide consensus guidance for resumption of EDX testing,...

Features of Enteric Disease from Human Coronaviruses: Implications for COVID-19.
https://doi.org/10.1002/jmv.26066
Journal of Medical Virology; Cimolai N

May 27th, 2020 - Coronaviruses have long been studied in both human and veterinary fields. Whereas the initial detection of endemic human respiratory coronaviruses was problematic, detection of these and newly discovered human coronaviruses has been greatly facilitated with major advances in the laboratory. Nevertheless, technological factors can affect the accuracy and timeliness of virus detection. Many human...

The COVID-19 epidemic of manuscripts.
https://doi.org/10.1111/jan.14437
Journal of Advanced Nursing; Watson R, Mark M

May 27th, 2020 - In the midst of the novel coronavirus pandemic-referred to as COVID-19-there has been much uncertainty. We remain uncertain about its precise origin, its structure and composition, how best to test for it, or for resulting immunity, whether or not exposure leads to immunity, whether or not disposable surgical masks are effective, why men and some ethnic minorities are more susceptible and just ...

Clinical features, isolation, and complete genome sequence of severe acute respiratory ...
https://doi.org/10.1002/jmv.26075
Journal of Medical Virology; Phan LT, Nguyen TV et. al.

May 27th, 2020 - In January 2020, we identified two SARS-CoV-2 infections in a familial cluster with one person coming from Wuhan, China. The complete genome sequences of two SARS-CoV-2 strains isolated from these patients were identical and 99.98% similar to strains isolated in Wuhan. This is genetically suggestive of human-to-human transmission of SARS-CoV-2 and indicates Wuhan as the most plausible origin of...

COVID-19: Consider IL6 receptor antagonist for the therapy of cytokine storm syndrome i...
https://doi.org/10.1002/jmv.26078
Journal of Medical Virology; Chakraborty C, Sharma AR et. al.

May 27th, 2020 - COVID-19 leads to mortality of several patients and the cytokine storm is reportedly critical in the patients. In order to reduce the cytokine storm, we would like to propose the IL6 receptor antagonist therapy for the COVID-19 patients. Two humanized monoclonal antibodies are in clinical trial following IL6R antagonist therapies namely tocilizumab and sarilumab. However, researchers and physic...

Practical Guide for Pediatric Pulmonologists on Imaging Management of Pediatric Patient...
https://doi.org/10.1002/ppul.24870
Pediatric Pulmonology; Foust AM, McAdam AJ et. al.

May 27th, 2020 - Understanding of coronavirus disease 2019 is rapidly evolving with new articles on the subject daily. This flood of articles can be overwhelming for busy practicing clinicians looking for key pieces of information that can be applied in daily practice. This review article synthesizes the reported imaging findings in pediatric COVID-19 across the literature, offers imaging differential diagnosti...

The Diagnosis of SARS-CoV2 Pneumonia: A Review of Laboratory and Radiological Testing R...
https://doi.org/10.1002/jmv.26081
Journal of Medical Virology; Zheng Z, Yao Z et. al.

May 27th, 2020 - The rapid emergence of COVID-19 (coronavirus disease 2019) has necessitated the implementation of diverse pandemic control strategies throughout the world. In order to effectively control the spread of this disease, it is essential that it be diagnosed at an early stage so that patients can be reliably quarantined such that disease spread will be slowed. At present, the diagnosis of this infect...

Impact of COVID-19 on the mental health of surgeons and coping strategies.
https://doi.org/10.1002/hed.26291
Head & Neck REFERENCES; Balasubramanian A, Paleri V et. al.

May 27th, 2020 - Unprecedented times call for extraordinary measures. While surgeons across the globe try to comprehend the evolving facade of the COVID-19 pandemic and improvise surgical practice to the best of their ability, the psychological impact of the stress on their own mental health and well-being has been underestimated. This paper aims to review the indirect and overt factors that may affect the ment...

Psychosocial Stress Contagion in Children and Families During the COVID-19 Pandemic.
https://doi.org/10.1177/0009922820927044
Clinical Pediatrics; Liu CH, Doan SN

May 27th, 2020 - Psychosocial Stress Contagion in Children and Families During the COVID-19 Pandemic.|2020|Liu CH,Doan SN,|

Why have nanotechnologies been underutilized in the global uprising against the coronav...
https://doi.org/10.2217/nnm-2020-0163
Nanomedicine (London, England); Uskoković V

May 27th, 2020 - Prior research on nanotechnologies in diagnostics, prevention and treatment of coronavirus infections is reviewed. Gold nanoparticles and semiconductor quantum dots in colorimetric and immunochromatographic assays, silica nanoparticles in a polymerase chain reaction and spike protein nanospheres as antigen carriers and adjuvants in vaccine formulations present notable examples in diagnostics an...

The COVID-19 Pandemic: A Challenge for the Cardiovascular Health.
https://doi.org/10.2174/1573403X1602200519115447
Current Cardiology Reviews; Crisafulli A, Pagliaro P

May 27th, 2020 - The COVID-19 Pandemic: A Challenge for the Cardiovascular Health.|2020|Crisafulli A,Pagliaro P,|

Exposure to DPP-4 inhibitors and COVID-19 among people with type 2 diabetes. A case-con...
https://doi.org/10.1111/dom.14097
Diabetes, Obesity & Metabolism; Fadini GP, Morieri ML et. al.

May 27th, 2020 - Because other coronaviruses enter the cells by binding to dipeptidyl-peptidase-4 (DPP-4), it has been speculated that DPP-4 inhibitors (DPP-4i) may exert an activity against SARS-CoV-2. In the absence of clinical trial results, we analyzed epidemiological data to support or discard such hypothesis. We retrieved information on exposure to DPP-4i among patients with type 2 diabetes (T2D) hospital...

Endogenous Deficiency of Glutathione as the Most Likely Cause of Serious Manifestations...
https://doi.org/10.1021/acsinfecdis.0c00288
ACS Infectious Diseases; Polonikov A

May 27th, 2020 - Higher rates of serious illness and death from coronavirus SARS-CoV-2 (COVID-19) infection among older people and those who have comorbidities suggest that age- and disease-related biological processes make such individuals more sensitive to environmental stress factors including infectious agents like coronavirus SARS-CoV-2. Specifically, impaired redox homeostasis and associated oxidative str...

Heightened risk of child maltreatment amid the COVID-19 pandemic can exacerbate mental ...
https://doi.org/10.1037/tra0000597
Psychological Trauma : Theory, Research, Practice and Policy; Cuartas J

May 27th, 2020 - The spread of the COVID-19 disrupted ecological systems in which children develop, exacerbating threats to their safety and increasing their vulnerability to future psychopathology. Supports to reduce sources of stress for caregivers and protect children from threats to their safety are warranted. (PsycInfo Database Record (c) 2020 APA, all rights reserved).

Stress and cognitive functioning during a pandemic: Thoughts from stress researchers.
https://doi.org/10.1037/tra0000716
Psychological Trauma : Theory, Research, Practice and Policy; Boals A, Banks JB

May 27th, 2020 - In this commentary we discuss a downstream consequence of increases in stress and anxiety during the COVID-19 pandemic. Stress and anxiety can lead to mind wandering, which in turn competes for limited cognitive resources. We encourage researchers to be understanding and patient concerning the inevitable cognitive impact of the pandemic and subsequent reduced productivity levels from our studen...

Shattered social identity and moral injuries: Work-related conditions in health care pr...
https://doi.org/10.1037/tra0000715
Psychological Trauma : Theory, Research, Practice and Policy; Kröger C

May 27th, 2020 - The present article assesses the effects of shattered social identity and moral injuries experienced by health care professionals (HCPs) due to the COVID-19 pandemic. Professional expertise and emotional-cognitive demands as key aspects of HCPs' social identity are introduced, and the effects of moral injuries-in terms of violation of medical-ethical and social-ethical norms-on the mental healt...

Raising awareness of disabled lives and health care rationing during the COVID-19 pande...
https://doi.org/10.1037/tra0000673
Psychological Trauma : Theory, Research, Practice and Policy; Lund EM, Ayers KB

May 27th, 2020 - Discriminatory and ableist health care rationing policies have raised serious concern in the disability community during the novel coronavirus pandemic. These concerns reflect the long-standing devaluation of disabled lives and place considerable weight on the disability community during this already stressful time. Nondisabled psychologists should work to advocate for the rights of people with...

Social representations, identity threat, and coping amid COVID-19.
https://doi.org/10.1037/tra0000773
Psychological Trauma : Theory, Research, Practice and Policy; Jaspal R, Nerlich B

May 27th, 2020 - This article describes an integrative social psychological framework within which human reactions to COVID-19 can be understood and predicted. It is argued that social representations of COVID-19 (and its mitigation strategies) must resonate among diverse communities, not be too threatening, and provide clear pathways for action and engagement. (PsycInfo Database Record (c) 2020 APA, all rights...

When chaos is the norm: How some veterans with PTSD are continuing to engage in trauma-...
https://doi.org/10.1037/tra0000718
Psychological Trauma : Theory, Research, Practice and Policy; Sciarrino NA, Myers US et. al.

May 27th, 2020 - The COVID-19 pandemic has caused many Veterans Healthcare Administration providers working with veterans diagnosed with posttraumatic stress disorder to question the feasibility and appropriateness of continuing to provide trauma-focused treatment during this crisis. The Veterans Healthcare Administration is in a unique position to continue to provide trauma-informed care because of its capacit...

Chloroquine or Hydroxychloroquine for COVID-19: Is Cardiotoxicity a Concern?
https://doi.org/10.1161/JAHA.120.016887
Journal of the American Heart Association; Kamp TJ, Hamdan MH et. al.

May 27th, 2020 - The SARS-Cov-2 viral pandemic causing COVID-19 disease begs for rapid and innovative treatments. In addition to flu-like respiratory symptoms, acute cardiac manifestations include cardiac injury, shock and arrhythmia. Several pharmacological therapies have been suggested including repurposing of existing drugs such as chloroquine and hydroxychloroquine, sometimes co-administered with azithromyc...

Experience with Hydroxychloroquine and Azithromycin in the COVID-19 Pandemic: Implicati...
https://doi.org/10.1161/JAHA.120.017144
Journal of the American Heart Association; Ramireddy A, Chugh H et. al.

May 27th, 2020 - Background Despite a lack of clinical evidence, hydroxychloroquine and azithromycin are being administered widely to patients with verified or suspected COVID-19. Both drugs may increase risk of lethal arrhythmias associated with QT interval prolongation. Methods and Results We performed a case series of COVID-19 positive/suspected patients admitted between 2/1/2020 and 4/4/2020 who were treate...

Conducting Clinical Research During the COVID-19 Pandemic: Protecting Scientific Integr...
https://doi.org/10.1001/jama.2020.9286
JAMA Fleming TR, Labriola D et. al.

May 27th, 2020 - Conducting Clinical Research During the COVID-19 Pandemic: Protecting Scientific Integrity.|2020|Fleming TR,Labriola D,Wittes J,|

Using Controlled Trials to Resolve Key Unknowns About Policy During the COVID-19 Pandemic.
https://doi.org/10.1001/jama.2020.8573
JAMA Starr P

May 27th, 2020 - Using Controlled Trials to Resolve Key Unknowns About Policy During the COVID-19 Pandemic.|2020|Starr P,|

Metatranscriptomic Characterization of COVID-19 Identified A Host Transcriptional Class...
https://doi.org/10.1093/cid/ciaa663
Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America; Zhang H, Ai JW et. al.

May 27th, 2020 - The recent identification of a novel coronavirus, also known as SARS-CoV-2, has caused a global outbreak of respiratory illnesses. The rapidly developing pandemic has posed great challenges to diagnosis of this novel infection. However, little is known about the metatranscriptomic characteristics of patients with Coronavirus Disease 2019 (COVID-19). We analyzed metatranscriptomics in 187 patien...

Positive impact of measures against COVID-19 on reducing influenza in the Northern Hemi...
https://doi.org/10.1093/jtm/taaa087
Journal of Travel Medicine; Chan CP, Wong NS et. al.

May 27th, 2020 - Positive impact of measures against COVID-19 on reducing influenza in the Northern Hemisphere.|2020|Chan CP,Wong NS,Leung CC,Lee SS,|

Alterations in smell or taste - Classic COVID-19?
https://doi.org/10.1093/cid/ciaa655
Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America; Trubiano JA, Vogrin S et. al.

May 27th, 2020 - Alterations in smell or taste - Classic COVID-19?|2020|Trubiano JA,Vogrin S,Kwong JC,Homes N,|

Prescription Fill Patterns for Commonly Used Drugs During the COVID-19 Pandemic in the ...
https://doi.org/10.1001/jama.2020.9184
JAMA Vaduganathan M, van Meijgaard J et. al.

May 27th, 2020 - Prescription Fill Patterns for Commonly Used Drugs During the COVID-19 Pandemic in the United States.|2020|Vaduganathan M,van Meijgaard J,Mehra MR,Joseph J,O'Donnell CJ,|

Treating the SARS-CoV-2-positive patient with cancer: A proposal for a pragmatic and tr...
https://doi.org/10.1002/cncr.32962
Cancer References; Perni S, Milligan MG et. al.

May 27th, 2020 - The treatment of patients with cancer who test positive for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) poses unique challenges. In this commentary, the authors describe the ethical rationale and implementation details for the creation of a novel, multidisciplinary treatment prioritization committee, including physicians, frontline staff, an ethicist, and an infectious disease ...

The AORN Community Displays its Resiliency Amidst Pandemic Crisis.
https://doi.org/10.1002/aorn.13062
AORN Journal; Groah LK

May 27th, 2020 - The AORN Community Displays its Resiliency Amidst Pandemic Crisis.|2020|Groah LK,|

Screen time for children and adolescents during the COVID-19 pandemic.
https://doi.org/10.1002/oby.22917
Obesity (Silver Spring, Md.); Nagata JM, Abdel Magid HS et. al.

May 27th, 2020 - The coronavirus 2019 (COVID-19) pandemic has led to laws and policies including national school closures, lockdown or shelter in place laws, and social distancing recommendations that may translate to higher overall screen time among children and adolescents for the duration of these laws and policies. These policies may need to be periodically re-instated to control future COVID-19 recurrences...

Management of Heart Failure Patients with COVID-19. A Joint Position Paper of the Chine...
https://doi.org/10.1002/ejhf.1915
European Journal of Heart Failure; Zhang Y, Stewart Coats AJ et. al.

May 27th, 2020 - The Coronavirus Disease 2019 (COVID-19) pandemic of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is causing considerable morbidity and mortality worldwide. Multiple reports have suggested that patients with heart failure (HF) are at a higher risk of severe disease and mortality with COVID-19. Moreover, evaluating and treating HF patients with comorbid COVID-19 represen...

Obesity and COVID-19: an Italian snapshot.
https://doi.org/10.1002/oby.22918
Obesity (Silver Spring, Md.); Busetto L, Bettini S et. al.

May 27th, 2020 - The clinical manifestations of COVID-19 run from asymptomatic disease to severe acute respiratory syndrome. Older age and comorbidities are associated to more severe disease. A role of obesity is suspected. We enrolled patients hospitalized in the medical COVID-19 ward with SARS-CoV-2 related pneumonia. Primary outcome of the study was to assess the relationship between the severity of COVID-19...

Possible Role of Adipose Tissue and Endocannabinoid System in COVID-19 Pathogenesis: Ca...
https://doi.org/10.1002/oby.22916
Obesity (Silver Spring, Md.); Briand-Mésange F, Trudel S et. al.

May 27th, 2020 - This is the main conclusion of a recent study describing a strong relationship between the degree of obesity and the severity of COVID-19 infection. Obesity has various negative consequences relative to the course of COVID-19, including adverse effects on lung physiology, and induces comorbidities such as type II diabetes or hypertension. However, additional mechanisms involving the low-grade i...

Global perspectives on Covid-19 from the editorial board.
https://doi.org/10.1111/tct.13167
The Clinical Teacher References; Thistlethwaite J, Locke R et. al.

May 27th, 2020 - Global perspectives on Covid-19 from the editorial board.|2020|Thistlethwaite J,Locke R,Buckley S,Chandratilake M,Jensen G,|

How medical education can help in a COVID-19 crisis.
https://doi.org/10.1111/tct.13183
The Clinical Teacher References; Roberts C

May 27th, 2020 - How medical education can help in a COVID-19 crisis.|2020|Roberts C,|

COVID-19: opportunities for professional development and disruptive innovation.
https://doi.org/10.1111/tct.13175
The Clinical Teacher References; McMaster D, Veremu M et. al.

May 27th, 2020 - COVID-19: opportunities for professional development and disruptive innovation.|2020|McMaster D,Veremu M,Santucci C,|

COVID-19 and the need to prioritize health equity and social determinants of health.
https://doi.org/10.1007/s00038-020-01398-z
International Journal of Public Health; Takian A, Kiani MM et. al.

May 27th, 2020 - COVID-19 and the need to prioritize health equity and social determinants of health.|2020|Takian A,Kiani MM,Khanjankhani K,|

Viewpoint: Impact of the Covid-19 Outbreak on the Clinical and Research Activities of M...
https://doi.org/10.14283/jpad.2020.17
The Journal of Prevention of Alzheimer's Disease; Ousset PJ, Vellas B

May 27th, 2020 - Viewpoint: Impact of the Covid-19 Outbreak on the Clinical and Research Activities of Memory Clinics: An Alzheimer's Disease Center Facing the Covid-19 Crisis.|2020|Ousset PJ,Vellas B,|

Asymptomatic transmission during the COVID-19 pandemic and implications for public heal...
https://doi.org/10.1093/cid/ciaa654
Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America; Huff HV, Singh A

May 27th, 2020 - SARS-CoV-2 spread rapidly within months despite global public health strategies to curb transmission by testing symptomatic patients and encouraging social distancing. Here, we summarize rapidly emerging evidence highlighting transmission by asymptomatic and pre-symptomatic individuals. Viral load of asymptomatic carriers is comparable to symptomatic patients, viral shedding is highest before s...

The Urgent Need for Medicare Reimbursement for Home Infusion Antibiotics amidst a Pande...
https://doi.org/10.1093/cid/ciaa658
Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America; Streifel AC, Sikka MK

May 27th, 2020 - The Centers for Medicare and Medicaid Services should immediately update current policies to include reimbursement for Medicare patients receiving intravenous antibiotics at home. The majority of these patients are over the age of 65 and at increased risk for severe illness due to severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). Requiring them to travel to an infusion center, stay ...

Letter: Using Continuous Intracranial Electroencephalography Monitoring to Manage Epile...
https://doi.org/10.1093/neuros/nyaa244
Neurosurgery Mirro EA, Halpern CH

May 27th, 2020 - Letter: Using Continuous Intracranial Electroencephalography Monitoring to Manage Epilepsy Patients During COVID-19.|2020|Mirro EA,Halpern CH,|

Clinical Utility of Buccal Swabs for Sars-Cov-2 Detection in Covid-19-Infected Children.
https://doi.org/10.1093/jpids/piaa068
Journal of the Pediatric Infectious Diseases Society; Kam KQ, Yung CF et. al.

May 27th, 2020 - SARS-CoV-2 was detected from at least 1 buccal specimen in 9 out of 11 COVID-19-infected children (81.8%). The viral loads in buccal specimens were substantially lower than those in nasopharyngeal specimens. Buccal swabs for SARS-CoV-2 are not good as screening specimens for COVID-19 in children.

Detecting Early Signals of COVID-19 Global Pandemic from Network Density.
https://doi.org/10.1093/jtm/taaa084
Journal of Travel Medicine; Chu AMY, Tiwari A et. al.

May 27th, 2020 - A novel use of network analysis in public health Developing a quantitative assessment method for the COVID-19 pandemic risk Exploring the time series of network density for early warning signals of pandemic risk Tracking the evolution of pandemic risk through the degree of connectedness.

Multisystem Inflammatory Syndrome in Children during the COVID-19 pandemic: a case series.
https://doi.org/10.1093/jpids/piaa069
Journal of the Pediatric Infectious Diseases Society; Chiotos K, Bassiri H et. al.

May 27th, 2020 - We present a series of six critically ill children with Multisystem Inflammatory Syndrome in Children (MIS-C). Key findings of this syndrome include fever, diarrhea, shock, and variable presence of rash, conjunctivitis, extremity edema, and mucous membrane changes.