Nocardia spp. infection should remain on the differential diagnosis of pneumonia in immunocompromised hosts, regardless of co-infections.

Online Report — Global Veterinary Diagnostic Laboratory Equipment Management and Sustainability and Implications for Pandemic Preparedness Priorities

Mar 29th, 2023 - Cardiovascular events were not more likely for recipients of the Pfizer-BioNTech COVID-19 mRNA bivalent booster compared with the original monovalent booster, according to French researchers. Their population-based study found no evidence of an increased risk of cardiovascular events at 21 days among the recipients of the bivalent vaccine versus recipients of the monovalent vaccine, including: ...

Mar 29th, 2023 - Transcatheter arterialization of the deep veins in patients with chronic limb-threatening ischemia appeared safe and led to limb salvage and wound healing in most cases, the PROMISE II study showed. The procedure to turn a vein into an artery for no-option patients was successful in all but one of the 105 trial participants (99.0%), with a 66.1% rate of amputation-free survival at 6 months, whi...

Mar 29th, 2023 - In certain groups of men, glucose-6-phosphate dehydrogenase (G6PD) deficiency was linked with an increased likelihood of severe COVID-19, a Veterans Affairs cohort study found. In Black men under 65, for example, those with the common enzyme deficiency had a roughly 1.5-fold higher risk for severe illness (OR 1.47, 95% CI 1.03-2.09), reported Lavannya Pandit, MD, MS, of the Michael E. DeBakey V...

Mar 29th, 2023 - Plasma exchange successfully improved symptoms of immunoglobulin A vasculitis in an adult female patient who developed the condition after infection with COVID-19, according to a case report published in Cureus. Immunoglobulin A (IgA) vasculitis can affect all ages, but is relatively rare in adults, and the etiology remains unclear, wrote Hassan Alwafi, MD, of Umm Al-Qura University, Makkah, Sa.

Mar 29th, 2023 - Note that some links may require subscriptions. A Florida woman wanted to talk to the hospital about her 4-year-old son's bill, but hospital officials said they couldn't speak with her because the bill was in her son's name. (NPR) The FDA approved the first over-the-counter naloxone (Narcan) product for reversing opioid overdoses. While over-the-counter naloxone could be lifesaving, some advoca...

Mar 28th, 2023 - Two groups of long COVID patients -- those hospitalized for acute COVID, and those with mild SARS-CoV-2 infection who weren't hospitalized -- had different neurologic manifestations, prospective data showed. Long COVID patients who were hospitalized with acute infection more frequently had an abnormal neurologic exam (62% vs 37%, P<0.0001) and performed worse on processing speed, attention, and...

Mar 28th, 2023 - An umbrella review of meta-analyses showed a positive overall effect of exercise on cognition, but the underlying studies had substantial limitations. (Nature Human Behaviour) SARS-CoV-2 infection during pregnancy was associated with a higher risk of neurodevelopmental disorders in male offspring. (JAMA Network Open) The FDA will hold an advisory committee meeting to discuss the investigational...

Mar 28th, 2023 - COVID-19 infection in the 60 days prior to surgery was not associated with risk of adverse postoperative outcomes, a cohort study among veterans showed. Of more than 29,000 veterans who underwent surgery, adverse postoperative outcomes occurred among 4.7% of those in the group without a recent COVID infection, 7.6% of those with a recent infection (1 to 30 day prior), and 3.2% of those with a s...

Mar 28th, 2023 - Nearly half of medical groups continue to require masking even as local public health officials have dropped mask mandates, according to a recent poll from the Medical Group Management Association (MGMA). Of 859 respondents, 49% said their office still has a mask requirement in place, while 51% said they do not. Among the medical groups that reported not having a mask requirement, nearly three-...

Mar 28th, 2023 - Government alcohol sales data were used to investigate associations between estimates of per capita age 15+ alcohol consumption, policy restrictiveness, and area-level deprivation. We analysed weekly consumption data (expressed as per capita age 15+ Canadian standard drinks [13.45g of pure ethanol]), collected from all 89 Local Health Areas in British Columbia, Canada, between April 2017 and Ap...

Mar 28th, 2023 - There has been concern regarding increased substance use during the COVID-19 pandemic, particularly among young adults, but much of this concern stemmed from cross-sectional or short-term data collected early in the pandemic. This study followed a young adult community cohort throughout the first year and a half of the pandemic to examine longer-term trends/trajectories in alcohol and cannabis ...

Mar 28th, 2023 - This study explores international faculty members' resilience and the active challenges to establishing coping mechanisms while facing a mental health crisis provoked by the Delta and Omicron lockdowns in China. Grounded in a qualitative approach, this study used a transcendental phenomenological methodology to examine 16 international faculty members affiliated with higher education institutio...

Mar 28th, 2023 - The prevalence of burnout in intensive care unit (ICU) professionals is difficult to establish due to the variety of survey instruments used, the heterogeneity of the targeted population, the design of the studies, and the differences among countries regarding ICU organization. We performed a systematic review and meta-analysis examining the prevalence of high-level burnout in physicians and nu...

Mar 28th, 2023 - The ongoing COVID-19 pandemic has revealed gender-specific differences between general practitioners in adapting to the posed challenges. As primary care workforce is becoming increasingly female, in many countries, it is essential to take a closer look at gender-specific influences when the global health care system is confronted with a crisis. To explore gender-specific differences in the per...

Mar 28th, 2023 - Multisystem inflammatory syndrome in children (MIS-C) associated with SARS-COV-2 in the immediate post-transplant period.|2023|Melere MU,Soares CS,Nader L,Farina M,Kalil AN,|

Mar 28th, 2023 - Testing and contact tracing (CT) can interrupt transmission chains SARS-CoV-2. Whole genome sequencing (WGS) can potentially strengthen these investigations and provide insights on transmission. We included all laboratory-confirmed COVID-19 cases diagnosed between June 4 to July 26, 2021, in a Swiss canton. We defined CT clusters based on epidemiological links reported in the CT data and genomi...

Mar 28th, 2023 - Saudi Arabia (SA) reported its first case of COVID-19 on 2 March 2020. Mortality varied nationwide; by April 14, 2020, Medina had 16% of SA's total COVID-19 cases and 40% of all COVID-19 deaths. A team of epidemiologists investigated to identify factors impacting survival. We reviewed medical records from two hospitals: Hospital A in Medina and Hospital B in Dammam. All patients with a register...

Mar 28th, 2023 - It is impossible to address the many complex needs of respiratory virus surveillance with a single system. Therefore, multiple surveillance systems and complementary studies must fit together as tiles in a "mosaic" to provide a complete picture of the risk, transmission, severity, and impact of respiratory viruses of epidemic and pandemic potential. Below we present a framework (WHO Mosaic Resp...

Mar 28th, 2023 - Although there has been an effective seasonal influenza vaccine available for more than 60 years, influenza continues to circulate and cause illness. The Eastern Mediterranean Region (EMR) is very diverse in health systems capacities, capabilities, and efficiencies, which affect the performance of services, especially vaccination, including seasonal influenza vaccination. The aim of this study ...

Mar 28th, 2023 - Human coronaviruses (HCoVs) 229E, OC43, HKU1, and NL63 are common viruses that continuously circulate in the human population. Previous studies showed the circulation of HCoVs during the cold months in Iran. We studied the circulation of HCoVs during coronavirus disease 2019 (COVID-19) pandemic to find the impact of pandemic on the circulation of these viruses. As a cross-sectional survey condu...

Mar 28th, 2023 - Respiratory syncytial virus (RSV) seasonality is dependent on the local climate. We assessed the stability of RSV seasonality prior to the SARS-CoV-2 pandemic in Western Australia (WA), a state spanning temperate and tropical regions. RSV laboratory testing data were collected from January 2012 to December 2019. WA was divided into three regions determined by population density and climate: Met...

Mar 28th, 2023 - The influenza A(H1N1)pdm09 pandemic highlighted the need for reliable disease burden estimation from low- and middle-income countries like Pakistan. We designed retrospective age-stratified estimation of influenza-related severe acute respiratory infections (SARIs) incidence in Islamabad Pakistan 2017-2019. The catchment area was mapped on SARI data from one designated influenza sentinel site a...

Mar 28th, 2023 - EMARIS Conference 2023: Convergence of science, policy, and practice on acute respiratory infections in post COVID-19 Eastern Mediterranean Region.|2023|Assiri A,Moen A,Brennan R,Abubakar A,Khan W,|

Mar 28th, 2023 - Social psychological scholarship has emphasized the importance of effective leadership during the COVID-19 pandemic. However, the wider material contexts of these dynamics have often remained understudied. Through a critical discursive lens, this paper investigates differences in the social constructions used by leaders of richer and poorer nations during the COVID-19 pandemic. We identify a sh...

Mar 28th, 2023 - To investigate determinants of willingness to adopt telerehabilitation, willingness of technology use, core affect regarding using telerehabilitation, and digital competencies in rehabilitation professionals in Austria and Germany before and during the COVID-19 pandemic. A cross-sectional paper-based and online survey was conducted before and during COVID-19, respectively, with three cohorts of...

Mar 28th, 2023 - The growing demand for palliative care has been accelerated due to the COVID-19 pandemic. However, providing community-based palliative care was also more difficult to do safely and faced several challenges. The goal of this integrative review was to identify, describe, and synthesize previous studies on the challenges for health professionals delivering palliative care in the community during ...

Mar 28th, 2023 - Nurses experienced intense ethical and moral challenges during the COVID-19 pandemic. Our 2020 qualitative parent study of frontline nurses' experiences during the COVID-19 pandemic identified ethics as a cross-cutting theme with six subthemes: moral dilemmas, moral uncertainty, moral distress, moral injury, moral outrage, and moral courage. We re-analyzed ethics-related findings in light of re...

Mar 28th, 2023 - Independent prescribing by nurses, pharmacists and allied health professionals is diversifying into a variety of healthcare settings as pressures mount on existing resources. Primary care was an early adopter of prescribing by non-medical professionals with resulting improvements in accessibility and flexibility of services but also noted barriers. Exploring existing prescribing activity within...

Mar 28th, 2023 - The impact of the COVID-19 pandemic on analytic training and the delivery of educational content is explored here. The proliferation of Zoom therapy and teaching is creating a post-human platform to which nearly everyone in contemporary society has had to adapt. Looking at the possible meanings of the pandemic, a psychoid factor (the virus) engaging the imagination has come to the fore as a res...

Mar 28th, 2023 - The aim of this study was to describe online prelicensure nursing students' experiences of incivility during COVID-19. Qualitative descriptive. Five optional open-ended questions were presented to nursing students to share their experiences with incivility during the pandemic. Data were collected from September to October 2020 as a part of a larger multimethod study on stress, resilience and in...

Mar 28th, 2023 - Disaggregated data on the mental health of Asian/Asian American people are needed to inform public health interventions related to reports of racism during the COVID-19 pandemic. We describe the prevalence of psychological distress and unmet mental health needs among Asian/Asian American adults during the COVID-19 pandemic across various sociodemographic subgroups. We used cross-sectional, weig...

Mar 28th, 2023 - Vaccinations against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have had a transformative impact on morbidity and mortality. However, the long-term impact of vaccination on patients with genitourinary cancers is currently unknown. This study aimed to assess seroconversion rates in patients with genitourinary cancers receiving COVID-19 vaccination. Patients with prostate cancer...

Mar 28th, 2023 - COVID-19 has affected many communities across the world prompting different strategies of containing it. The strategies to contain COVID-19 included restrictive environments such as self-isolation and quarantine. This research study was set to explore the experiences of quarantined individuals arriving in the United Kingdom (UK) from red listed countries in Southern Africa. This research study ...

Mar 28th, 2023 - Acute Kidney Injury (AKI) complicates a substantial part of patients with COVID-19. Direct viral penetration of renal cells through the Angiotensin Converting Enzyme 2 receptor, and indirect damage by the aberrant inflammatory response characteristic of COVID-19 are likely mechanisms. Nevertheless, other common respiratory viruses such as Influenza and Respiratory Syncytial Virus (RSV) are also...

Mar 28th, 2023 - The use of alcohol-based sanitizers has been recommended as an effective alternative to clean hands, especially in the case when hand washing is not doable. This is especially critical with the COVID-19 pandemic, where personal hygiene is an important factor to deter the spread of the virus. This study assesses and evaluates the differences in antibacterial efficacy and functionalities of five ...

Mar 28th, 2023 - Stay-at-home strategies taken during the COVID-19 pandemic changed our lifestyle drastically. Although marital status and household size are important social determinants of health that affect lifestyle, their impacts on lifestyle during the pandemic are still unclear. We aimed to evaluate the association between marital status, household size, and lifestyle changes during the first pandemic in...

Mar 28th, 2023 - Common psychosocial health problems (PHPs) have become more prevalent among adolescents globally during the COVID-19 pandemic. However, the psychosocial health of school-going adolescents has remained unexplored in Bangladesh due to limited research during the pandemic. The present study aimed to estimate the prevalence of PHPs (i.e., depression and anxiety) and assess associated lifestyle and ...

Mar 28th, 2023 - Tuberculosis (TB) remains a major public health problem globally, even compared to COVID-19. Genome-wide studies have failed to discover genes that explain a large proportion of genetic risk for adult pulmonary TB, and even fewer have examined genetic factors underlying TB severity, an intermediate trait impacting disease experience, quality of life, and risk of mortality. No prior severity ana...

Mar 28th, 2023 - Mutations continue to accumulate within the SARS-CoV-2 genome, and the ongoing epidemic has shown no signs of ending. It is critical to predict problematic mutations that may arise in clinical environments and assess their properties in advance to quickly implement countermeasures against future variant infections. In this study, we identified mutations resistant to remdesivir, which is widely ...

Mar 28th, 2023 - Poor disease outcomes and lethality are directly related to endothelial dysfunction in betacoronavirus infections. Here, we investigated the mechanisms underlying the vascular dysfunction caused by the betacoronaviruses MHV-3 and SARS-CoV-2. Wild-type C57BL/6 (WT) and knockout mice for inducible nitric oxide synthase (iNOS-/-) or TNF receptor 1 (TNFR1-/-) were infected with MHV-3, and K18-hACE2...

Mar 28th, 2023 - This study investigated the implementation of a curricular unit of instruction designed to immerse rising ninth-grade students socioscientific issues via data collection and analysis of the relationships between health, wealth, educational attainment, and the impact of the COVID-19 Pandemic on their communities. Twenty-six (n = 26) rising ninth-grade students (14-15 years old; 16 girls, 10 boys...

Mar 28th, 2023 - COVID-19 is associated with cardiac dysfunction. This study tested the relative prognostic role of left (LV), right and bi- (BiV) ventricular dysfunction on mortality in a large multicenter cohort of patients during and after acute COVID-19 hospitalization. All hospitalized COVID-19 patients who underwent clinically indicated transthoracic echocardiography within 30 days of admission at four NY...

Mar 28th, 2023 - Covid-19 response: a perspective from Pakistan.|2023|Mirza Z,|

Mar 28th, 2023 - Neutropenic Fever-Associated Admissions Among Patients With Solid Tumors Receiving Chemotherapy During the COVID-19 Pandemic.|2023|Baus CJ,Kelley B,Dow-Hillgartner E,Kyriakopoulos CE,Schulz LT,|

Mar 28th, 2023 - Uptake of vaccination against COVID-19 is strongly affected by concerns about adverse effects. Research on nocebo effects suggests that these concerns can amplify symptom burden. To investigate whether positive and negative expectations prior to COVID-19 vaccination are associated with systemic adverse effects. This prospective cohort study analyzed the association of expected benefits and risk...

Mar 28th, 2023 - Throughout the COVID-19 pandemic, policy makers have tried to balance the effectiveness of lockdowns (i.e., stay-at-home orders) with their potential mental health costs. Yet, several years into the pandemic, policy makers lack solid evidence about the toll of lockdowns on daily emotional functioning. Using data from two intensive longitudinal studies conducted in Australia in 2021, we compared...

Mar 28th, 2023 - Sources of bias in observational studies of covid-19 vaccine effectiveness.|2023|Fung K,Jones M,Doshi P,|

Mar 28th, 2023 - Coronavirus disease 2019 (COVID-19) has been proposed as triggering autoimmunity. The aim of this study was to evaluate the presence and clinical significance of autoantibodies in patients with COVID-19. We retrospectively collected data from 245 patients who were hospitalized for COVID-19. All patients were tested for the presence of antinuclear antibody (ANA), rheumatoid factor (RF), anti-cit...