Aug 6th, 2020 - For Immediate Release: August 06, 2020 The U.S. Food and Drug Administration today announced the following actions taken in its ongoing response effort to the COVID-19 pandemic: On August 4, the FDA issued Emergency Use Authorizations (EUAs) for ventilator-related devices to: Lombardi Undersea, for its Subsalve Oxygen Treatment Hood, which is a patient interface intended for helmet-based Non-In...

Aug 5th, 2020 - The pandemic caused by the coronavirus disease 2019 (COVID-19) infection has exposed vulnerable populations to an unprecedented global health crisis. Research reported that Chinese traditional medicine injections were used in patients with COVID-19 infection and showed significant effects, and there have been no systematic review and meta-analyses to investigate the effects and safety of Chines...

Aug 5th, 2020 - A sudden onset of anosmia has been recently recognized as a symptom of coronavirus disease (COVID-19). Here, we describe a case of complete anosmia in a young male with COVID-19. Although he had fever and odynophagia, no abnormalities were observed in his nasopharyngeal mucosa, suggesting that his anosmia resulted from olfactory neuropathy. COVID-19 was confirmed by RNA detection in nasopharyng...

Aug 5th, 2020 - Since December 2019, there have been many cases of viral pneumonia of unknown causes in Wuhan City, Hubei Province. During the period of novel coronavirus, according to the observation of limited autopsy and biopsy pathological results, pulmonary interstitial fibrosis appeared in some pathological changes of lung. Idiopathic pulmonary fibrosis (IPF) is a chronic progressive interstitial pneumon...

Aug 5th, 2020 - Corona Virus Disease 2019 (COVID-19) is spreading fast starting late 2019. It mainly affects the human respiratory system. Many reports revealed that rehabilitation exercise can improve respiratory function and relieve the pressure from diseases, but there is no evidence to prove its effects on COVID-19. This protocol of systematic review and meta-analysis will clarify the safety and effectiven...

Aug 5th, 2020 - The pandemic following the rapid spread of the new SARS-CoV-2 virus has hit all continents and caused thousands of deaths worldwide. Evidence has been published on epidemiological and clinical characteristics of population groups considered at risk; however, information for the other population groups, especially for the child population, is needed. In this context, this protocol describes a sy...

Aug 5th, 2020 - The world is facing the pandemic linked to COVID-19 virus infection that has rapidly spread worldwide, and severe complications have been reported to occur in around a third of patients. To date, there is no approved vaccine or specific therapy against COVID-19, but many trials are ongoing with some of them showing promising results. It has been shown recently that patients with cancer are at h...

Aug 5th, 2020 - Peripheral blood abnormalities in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have not been fully elucidated. We report qualitative and quantitative peripheral blood findings in coronavirus disease 2019 (COVID-19) patients and compare them with a control group. We reviewed electronic medical records, complete blood counts, peripheral blood smears, and flow cytometry data in 12 ...

Aug 5th, 2020 - The disruption and contraction of older adults' social networks are among the less-discussed consequences of the COVID-19 pandemic. Our objective is to provide an evidence-based commentary on racial/ethnic disparities in social network resources and draw attention to the ways in which disasters differentially impact social networks, with meaningful insight for the ongoing pandemic. We draw upon...

Aug 5th, 2020 - Audio Interview: The Impact of Covid-19 on Patients with Other Diseases, with Arnold Epstein.|2020|Rubin EJ,Baden LR,Epstein A,Morrissey S,|

Aug 5th, 2020 - Coronavirus disease 2019 (COVID-19) has become a pandemic in the world and posed a great threat to people's health. Several meta-analyses have indicated that many comorbidities were associated with increased risk of COVID-19 severity or mortality. The original report also showed that the mortality rate of COVID-19 in breast cancer patients is more dependent on comorbidities than previous radiat...

Aug 5th, 2020 - Syncope is described as the loss of consciousness and postural muscle tone with a short duration and fast onset. Micturition syncope can be caused by abnormal vasovagal response or by the dysfunction of the blood pressure regulating mechanism, which occurs before, during, or immediately after urination. We present 4 cases of COVID-19 hospitalized in the Department of Infectious Diseases of the ...

Aug 5th, 2020 - Cardiac injury and coagulation disorders have been two increasing concerns in the management of patients with severe coronavirus disease (COVID-19). Coagulation disorders in COVID-19 patients with cardiac injury have not been characterized. We analyzed the data of five COVID-19 patients with cardiac injury who had D-dimer surge (defined as a rapid increase in the D-dimer level in 72 h, from <5-...

Aug 5th, 2020 - Since the coronavirus disease 2019 (COVID-19) outbreak in Wuhan in late 2019, controversy on the use of corticosteroids for COVID-19 has obtained increasing attention. We present 1 critically ill patient who had a rapid therapeutic response to moderate-dose corticosteroids. A 53-year-old critically ill woman from Wuhan suffered with COVID-19. The chest computed tomography scan was suggestive of...

Aug 5th, 2020 - The COVID-19 cases increased very fast in January and February 2020. The mortality among critically ill patients, especially the elder ones, is relatively high. Considering many patients died of severe inflammation response, it is urgent to develop effective therapeutic strategies for these patients. The human umbilical cord mesenchymal stem cells (hUCMSCs) have shown good capabilities to modul...

Aug 5th, 2020 - Coronavirus disease-2019 (COVID-19) is an ongoing pandemic which has affected over 12 million people across the globe. Manifestations in different organs systems are being reported regularly. Renal biopsy findings in hospitalized COVID-19 patients presenting solely with acute kidney injury (AKI) have recently been described in published literature in few case reports. The findings include diffu...

Aug 5th, 2020 - Innovation Lessons From the COVID-19 Pandemic.|2020|Farrugia G,Plutowski RW,|

Aug 5th, 2020 - Clinical Trial End Points in Severe COVID-19.|2020|Desai A,Kulkarni A,Rajkumar SV,Gyawali B,|

Aug 5th, 2020 - Cardiovascular Health in the COVID-19 Era: A Call for Action and Education.|2020|Vallabhajosyula S,Friedman PA,Bell MR,|

Aug 5th, 2020 - To confirm whether a relationship exists between male sex and coronavirus disease 2019 (COVID-19) mortality and whether this relationship is age dependent. We queried the COVID-19 Research Network, a multinational database using the TriNetX network, to identify patients with confirmed COVID-19 infection. The main end point of the study was all-cause mortality. A total of 14,712 patients were in...

Aug 5th, 2020 - To estimate the prevalence of olfactory and gustatory dysfunctions (OGDs) among patients infected with novel coronavirus disease 2019 (COVID-19). A systematic review was conducted by searching MEDLINE, EMBASE, and the preprint server MedRxiv from their inception until May 11, 2020, using the terms anosmia or hyposmia or dysosmia or olfactory dysfunction or olfaction disorder or smell dysfunctio...

Aug 5th, 2020 - To perform a systematic review and meta-analysis evaluating the prevalence of gastrointestinal (GI) symptoms and mortality in patients with coronavirus disease 2019 (COVID-19) diagnosed. A systematic search of MEDLINE, EMBASE, Cochrane Central Register of Controlled Trials, Cochrane Database of Systematic Reviews, and Scopus was performed from December 1, 2019 to May 7, 2020. Observational stud...

Aug 5th, 2020 - Among candidate drugs to treat coronavirus disease 2019 (COVID-19), the combination of hydroxychloroquine (HCQ) and azithromycin (AZ) has received intense worldwide attention. Even as the efficacy of this combination is under evaluation, clinicians have begun to use it largely. As these medications are known to prolong the QT interval, we analyzed serial electrocardiograms recorded in patients ...

Aug 5th, 2020 - The possibility of seasonality of COVID-19 is being discussed; we show clinical microbiology laboratory data illustrating seasonality of coronaviruses 229E, HKU1, NL63, and OC43. The data shown are specific to the 4 studied coronaviruses and may or may not generalize to COVID-19.

Aug 5th, 2020 - On March 11, 2020, the World Health Organization declared the coronavirus disease 2019 (COVID-19) a pandemic, and in the weeks following, public health organizations, medical associations, and governing bodies throughout the world recommended limiting contact with others to "flatten the curve" of COVID-19. Although both ischemic and hemorrhagic strokes have been reported with COVID-19, there ha...

Aug 5th, 2020 - Given the rapid spread of the coronavirus disease 2019 (COVID-19) pandemic and its overwhelming effect on health care systems and the global economy, innovative therapeutic strategies are urgently needed. The proposed primary culprit of COVID-19 is the intense inflammatory response-an augmented immune response and cytokine storm-severely damaging the lung tissue and rendering some patients' con...

Aug 5th, 2020 - The global pandemic of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the cause of coronavirus disease 2019 (COVID-19), has been associated with worse outcomes in several patient populations, including the elderly and those with chronic comorbidities. Data from previous pandemics and seasonal influenza suggest that pregnant women may be at increased risk for infection-associated ...

Aug 5th, 2020 - Covid-19: NHS Test and Trace must improve for schools to reopen safely, say researchers.|2020|Wise J,|

Aug 5th, 2020 - Covid-19: UK hospitals to get rapid tests from September.|2020|Mahase E,|

Aug 5th, 2020 - There are widespread shortages of personal protective equipment as a result of the COVID-19 pandemic. Reprocessing filtering facepiece particle (FFP)-type respirators may provide an alternative solution in keeping healthcare professionals safe. Prospective, bench-to-bedside. A primary care-based study using FFP-2 respirators without exhalation valve (3M Aura 1862+ (20 samples), Maco Pharma ZZM0...

Aug 5th, 2020 - In March 2020, the WHO declared the COVID-19 disease as a pandemic disease. There have been studies on the COVID-19 to find a certain treatment, but yet, there is no certain cure. In this article, we present a possible way to treat severe cases of COVID-19. Based on the previous studies, there are similarities between the spike antigens of SARS-CoV and SARS-CoV-2 viruses. It is expected that th...

Aug 5th, 2020 - The pandemic of the Covid-19 virus has become the main issue all over the world. In its current form, the disease is more severe in geriatric cases and individuals with chronic disease, even causing death. In older adults and atypical presentations, testing strategies for Covid-19, potential drug interactions of experimental Covid-19 therapies, and ageism are important issues in the course of t...

Aug 5th, 2020 - Retraction of: No Deleterious Effect of Lockdown Due to COVID-19 Pandemic on Glycaemic Control, Measured by Glucose Monitoring, in Adults with Type 1 Diabetes. Beato-Vibora PI. Diabetes Technol Ther 2020; epub DOI: 10.1089/dia.2020.0184.|2020||

Aug 5th, 2020 - For Immediate Release: August 05, 2020 The U.S. Food and Drug Administration today announced the following actions taken in its ongoing response effort to the COVID-19 pandemic: The FDA issued its first warning letter to New Life International and its second warning letter to Fishman Chemical of North Carolina, LLC, both of which distribute chloroquine phosphate products intended to treat disea...

Aug 4th, 2020 - COVID-19: Education and Licensure Disruption.|2020|Stolberg RL,|

Aug 4th, 2020 - Two decades of pandemic war games failed to account for Donald Trump.|2020|Maxmen A,Tollefson J,|

Aug 4th, 2020 - Pneumomediastinum is a rare clinical finding, but one which can be the source of significant concern for clinicians. By presenting 3 such cases, we highlight that pneumomediastinum can complicate the course of a severe coronavirus disease 2019 infection but emphasize that conservative management is the first-line method of treatment, with gradual resorption of the air from the tissues. It is im...

Aug 4th, 2020 - Long term respiratory complications of covid-19.|2020|Fraser E,|

Aug 4th, 2020 - Covid-19: US needs a national plan to fight rising infections, experts say.|2020|Tanne JH,|

Aug 4th, 2020 - Covid-19: Should the UK be aiming for elimination?|2020|Torjesen I,|

Aug 4th, 2020 - Inequities During COVID-19.|2020|Ambrose AJH,|

Aug 4th, 2020 - Telemedicine and Health Disparities During COVID-19.|2020|Katzow MW,Steinway C,Jan S,|

Aug 4th, 2020 - The COVID-19/SARS-CoV-2 pandemic struck health, social and economic systems worldwide, and represents an open challenge for scientists -coping with the high inter-individual variability of COVID-19, and for policy makers -coping with the responsibility to understand environmental factors affecting its severity across different geographical areas. Air pollution has been warned of as a modifiable...

Aug 4th, 2020 - Coronavirus Disease 2019 (COVID-19) has affected day to day life and slowed down the global economy. Most countries are enforcing strict quarantine to control the havoc of this highly contagious disease. Since the outbreak of COVID-19, many data analyses have been done to provide close support to decision-makers. We propose a method comprising data analytics and machine learning classification ...

Aug 4th, 2020 - The coronavirus disease 2019 (COVID-19) pandemic has created challenges that have caused profound changes in health behaviors. This study aimed to explore how COVID-19 is affecting the health-related quality of life (QoL) among Chinese adults. The data of health-related behaviors and QoL were collected via online surveys from 2289 adults (mean age = 27.8 ± 12 years) who had been isolated at hom...

Aug 4th, 2020 - The COVID-19 pandemic is an unprecedented healthcare emergency causing mortality and illness across the world. Although primarily affecting the lungs, the SARS-CoV-2 virus also affects the cardiovascular system. In addition to cardiac effects, e.g. myocarditis, arrhythmias, and myocardial damage, the vasculature is affected in COVID-19, both directly by the SARS-CoV-2 virus, and indirectly as a...

Aug 4th, 2020 - To explore any relationship between the ABO blood group and the COVID-19 susceptibility, we compared ABO blood group distributions in 2,173 COVID-19 patients with local control populations, and found that blood group A was associated with an increased risk of infection, whereas group O was associated with a decreased risk.

Aug 4th, 2020 - The recent development and regulatory approval of a variety of serological assays indicating the presence of antibodies against severe acute respiratory syndrome coronavirus 2 has led to rapid and widespread implementation of seroprevalence studies. Accurate estimates of seroprevalence are needed to model transmission dynamics and estimate mortality rates. Furthermore, seroprevalence levels in ...

Aug 4th, 2020 - Severe acute respiratory syndrome-coronavirus 2 (SARS-Cov-2) has caused over 13,000,000 cases of coronavirus disease (COVID-19) with a significant fatality rate. Laboratory mice have been the stalwart of therapeutic and vaccine development; however, they do not support infection by SARS-CoV-2 due to the virus's inability to use the mouse orthologue of its human entry receptor angiotensin-conver...

Aug 4th, 2020 - The COVID-19 pandemic has created many challenges for pediatric solid organ transplant (SOT) recipients and their families. As the pandemic persists, patients and their families struggle to identify the best and safest practices for resuming activities as areas re-open. In particular, decisions about returning to school remain difficult. We assembled a team of pediatric infectious diseases, tra...