Oct 21st, 2020 - Several coronavirus disease 2019 (COVID-19) vaccines are currently in human trials. In June 2020, we surveyed 13,426 people in 19 countries to determine potential acceptance rates and factors influencing acceptance of a COVID-19 vaccine. Of these, 71.5% of participants reported that they would be very or somewhat likely to take a COVID-19 vaccine, and 61.4% reported that they would accept their...

Oct 21st, 2020 - The pandemic of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) resulted in an unprecedented public health challenge worldwide. Despite urgent and extensive global efforts, the existing evidence is inconclusive regarding the medications used for the treatment of COVID-19. To generate an up-to-date evidence for the clinical safety and ef...

Oct 21st, 2020 - A systematic review of mental health outcomes and needs of children and families during past pandemics was conducted based on the PRISMA protocol. The objectives were to evaluate the quality of existing studies on this topic, determine what is known about mental health outcomes and needs of children and families, and provide recommendations for how COVID-19 policies can best support children an...

Oct 21st, 2020 - It is critical to identify potential causal targets for SARS-coronavirus 2, which may guide drug repurposing options. We assessed the associations between genetically predicted protein levels and COVID-19 severity. Leveraging data from The COVID-19 host genetics initiative comparing 6,492 hospitalized COVID-19 patients and 1,012,809 controls, we identified 18 proteins with genetically predicted...

Oct 21st, 2020 - Extra-cardiac multifocal lung uptake of 99mTc-sestamibi in myocardial perfusion imaging: An asymptomatic case with coronavirus infection features.|2020|Malek H,Maghsudi M,Yaghoobi N,|

Oct 21st, 2020 - This paper presents a brief overview of the complex interaction between age, hypertension, the renin-angiotensin-aldosterone system (RAAS), inflammation, and severe acute respiratory syndrome coronavirus 2 (SARS-CoV2) infection. Coronavirus disease 2019 (COVID-19) is more frequent and more severe in comorbid elderly patients, especially those with hypertension, diabetes, obesity, or cardiovascu...

Oct 21st, 2020 - The cytokine storm has been frequently reported to occur in patients with severe coronavirus disease 2019 (COVID-19). Data from the literature suggest that elevated levels of inflammatory mediators, such as interleukin (IL)-6, IL-8, and tumor necrosis factor, indicate a severe course or the fatality of the disease. Several therapeutic options have been employed to treat critically ill patients,...

Oct 21st, 2020 - SARS-CoV-2 has emerged as a human pathogen, causing clinical signs, from fever to pneumonia - COVID-19 - but may remain mild or asymptomatic. To understand the continuing spread of the virus, to detect those who are and were infected, and to follow the immune response longitudinally, reliable and robust assays for SARS-CoV-2 detection and immunological monitoring are needed. We quantified immun...

Oct 21st, 2020 - Treatment of COVID-19 induced chilblains with topical nitroglycerin.|2020|Weingarten M,Abittan B,Rivera-Oyola R,Abittan AI,Weingarten M,|

Oct 21st, 2020 - Two cases of skin manifestations prior to the onset of COVID-19 respiratory symptoms.|2020|Altayeb A,Cordaro A,Caesar J,Vyas J,Ingram J,|

Oct 21st, 2020 - Italy was severely affected by the severe acute respiratory syndrome coronavirus 2 pandemic. Our Institution, Piedmont's largest tertiary referral center, was designated as a non-COVID-19 hospital and activities were reorganized to prioritize critical services like oncological care. The aim of this study was to investigate the efficacy in preserving the oncological surgical practice at our Inst...

Oct 21st, 2020 - Obesity is a global health problem that affects all age groups in both developing and developed countries. In recent years, the prevalence of overweight and obesity has reached pandemic levels, resulting in a dramatic increase in the incidence of various comorbidities, such as cardiovascular diseases, type 2 diabetes, and cancer, consequently leading to massive health and socioeconomic burdens....

Oct 21st, 2020 - The coronavirus disease 2019 (COVID-19) pandemic has put an enormous strain on healthcare systems and intensive care unit (ICU) capacity, leading to suspension of most elective procedures, including transcatheter aortic valve replacement (TAVR). However, deferment of TAVR is associated with significant wait-time mortality in patients with severe aortic valve stenosis. Conversely, there is curre...

Oct 21st, 2020 - It is unknown if solid organ transplant recipients are at higher risk for severe COVID-19. The management of a lung transplantation (LTx) program and the therapeutic strategies to adapt the immunosuppressive regimen and antiviral measures is a major issue in the COVID-19 era, but little is known about worldwide practice. We sent out to 180 LTx centers worldwide in June 2020 a survey with 63 que...

Oct 21st, 2020 - In light of the current evolving coronavirus disease 2019 (COVID-19) pandemic, and the need to learn from past infectious disease outbreaks to provide better psychological support for our frontline health care workers (HCW), we conducted a rapid review of extant studies that have reported on both psychological and coping responses in HCW during recent outbreaks. We performed a systematic search...

Oct 21st, 2020 - Rebuilding survivorship care during Covid-19.|2020|Pagedar NA,Seaman AT,|

Oct 21st, 2020 - The risk of environmental contamination by SARS-CoV-2 in the intensive care unit (ICU) is unclear. We aimed to evaluate the extent of environmental contamination in the ICU and correlate this with patient and disease factors, including the impact of different ventilatory modalities. Observational study where surface environmental samples collected from ICU patient rooms and common areas were te...

Oct 21st, 2020 - During the world-wide coronavirus disease 2019 (COVID-19) outbreak, there is an urgent need to rapidly increase the readiness of hospitals. Emergency departments (EDs) are at high risk of facing unusual situations and need to prepare extensively in order to minimize risks to health care providers (HCPs) and patients. In situ simulation is a well-known method used in training to detect system ga...

Oct 21st, 2020 - Mental health and wellbeing during the COVID-19 pandemic: longitudinal analyses of adults in the UK COVID-19 Mental Health & Wellbeing study.|2020|O'Connor RC,Wetherall K,Cleare S,McClelland H,Melson AJ,|

Oct 21st, 2020 - Neurological Manifestations in Coronavirus Disease 2019 (COVID-19) Patients: A Systematic Review of Literature.|2020|Ibrahim W,|