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From nicotine to the cholinergic anti-inflammatory reflex - Can nicotine alleviate the ...
https://doi.org/10.1080/1547691X.2021.1875085
Journal of Immunotoxicology; Gauthier AG, Lin M et. al.

Apr 16th, 2021 - The coronavirus SARS-CoV-2 of 2019 (COVID-19) causes a pandemic that has been diagnosed in more than 70 million people worldwide. Mild-to-moderate COVID-19 symptoms include coughing, fever, myalgia, shortness of breath, and acute inflammatory lung injury (ALI). In contrast, acute respiratory distress syndrome (ARDS) and respiratory failure occur in patients diagnosed with severe COVID-19. ARDS ...

The role of digital health technologies in COVID-19 surveillance and recovery: a specif...
https://doi.org/10.1080/09540261.2020.1854195
International Review of Psychiatry (Abingdon, England); Southwick L, Guntuku SC et. al.

Apr 16th, 2021 - Digital health and technologies are essential to curbing the novel coronavirus 2019 (COVID-19) pandemic especially with shelter-in-place and social distancing orders. Epidemiologists and public health officials are tapping into frequently used technologies like wearables, digital devices, digital and social media data to detect and validate COVID-19 symptoms throughout the pandemic, especially ...

Induction of Exaggerated Cytokine Production in Human Peripheral Blood Mononuclear Cell...
https://doi.org/10.1007/s10753-021-01464-5 10.1056/NEJMoa2001017 10.1038/s41586-020-2012-7 10.1016/S0140-6736(20)30183-5 10.1684/ecn.2020.0451 10.1016/j.lfs.2020.118923 10.1038/s41392-020-00243-2 10.1016/j.jinf.2020.06.008 10.1002/jmv.25948 10.3390/v12030254 10.1038/s41392-020-0191-1 10.1016/j.chom.2020.04.009 10.1038/s41577-020-0331-4 10.3389/fimmu.2020.01518 10.1016/j.cell.2020.02.058 10.3389/fimmu.2020.576622 10.1002/mnfr.201801237 10.1007/s10787-020-00720-8 10.1172/JCI137244 10.1093/cid/ciaa248 10.1186/s12879-020-05681-5 10.1016/S2213-2600(20)30076-X 10.1155/2020/8198963 10.1080/22221751.2020.1770129 10.1016/j.jaci.2020.09.018 10.1016/j.cyto.2018.01.025 10.1111/j.1365-2249.2004.02415.x 10.1007/s00281-017-0629-x 10.1099/vir.0.055533-0 10.1001/jama.2020.17021 10.1046/j.1432-1327.1998.2540081.x 10.1016/S0162-3109(00)00199-5 10.1016/j.tox.2007.03.024 10.1371/journal.pone.0189643 10.1038/s41590-020-0778-2 10.1038/nri3495 10.1007/s00204-015-1472-2 10.1038/372739a0 10.1016/j.bbamcr.2007.03.010 10.1016/j.smim.2014.02.009 10.1016/j.phrs.2020.104850 10.1016/j.cell.2020.06.034 10.3346/jkms.2020.35.e343 10.1084/jem.20201707
Inflammation Olajide OA, Iwuanyanwu VU et. al.

Apr 16th, 2021 - An understanding of the pathological inflammatory mechanisms involved in SARS-CoV-2 virus infection is necessary in order to discover new molecular pharmacological targets for SARS-CoV-2 cytokine storm. In this study, the effects of a recombinant SARS-CoV-2 spike glycoprotein S1 was investigated in human peripheral blood mononuclear cells (PBMCs). Stimulation of PBMCs with spike glycoprotein S1...

Autonomic dysfunction following COVID-19 infection: an early experience.
https://doi.org/10.1007/s10286-021-00803-8 10.1002/ana.25807 10.1007/s10286-020-00727-9 10.19102/icrm.2020.111102 10.1007/s10286-020-00733-x 10.1016/j.ensci.2020.100276 10.1007/s10286-021-00783-9 10.12691/ajmcr-9-3-16 10.1080/00207454.2021.1886097 10.1007/s10286-017-0425-7 10.1016/j.clinph.2020.11.024 10.1097/00004691-199301000-00003 10.1002/ana.410140513 10.1212/01.wnl.0000184504.13173.ef 10.1016/s0025-6196(12)60631-4 10.1016/S0025-6196(12)65338-5 10.1212/wnl.43.1_part_1.132 10.1136/jnnp.47.6.648 10.1016/0016-5085(91)90609-o 10.1016/j.clineuro.2020.106349 10.1056/NEJMoa2001017 10.1016/S0140-6736(20)30154-9 10.1016/S0140-6736(20)30183-5 10.1186/s12888-021-03108-2
Clinical Autonomic Research : Official Journal of the Cli... Shouman K, Vanichkachorn G et. al.

Apr 16th, 2021 - Post-COVID-19 syndrome is a poorly understood aspect of the current pandemic, with clinical features that overlap with symptoms of autonomic/small fiber dysfunction. An early systematic analysis of autonomic dysfunction following COVID-19 is lacking and may provide initial insights into the spectrum of this condition. We conducted a retrospective review of all patients with confirmed history of...

Aging versus youth: Endocrine aspects of vulnerability for COVID-19.
https://doi.org/10.1007/s11154-021-09656-y 10.3389/fimmu.2020.01708 10.1007/s00281-020-00818-9 10.1016/j.tem.2016.09.005 10.1038/nm.4000 10.1016/0014-4827(65)90211-9 10.18632/aging.104097 10.1111/acel.13237 10.1111/acel.13234 10.1016/j.exger.2017.08.019 10.1007/s13238-020-00762-2 10.1016/j.mito.2020.06.008 10.3389/fimmu.2020.01748 10.1016/S1286-4579(01)01443-5 10.1385/IR:29:1-3:113 10.1111/acel.12320 10.1074/jbc.R700009200 10.1089/vim.2011.0099 10.1093/cid/ciaa410 10.1126/science.aaf3926 10.1016/S1473-3099(20)30196-1 10.1086/503843 10.1016/j.immuni.2018.12.027 10.1007/978-3-319-99375-1_92 10.1007/978-3-319-99375-1_46 10.3389/fimmu.2020.01312 10.1007/978-3-319-99375-1_26 10.1111/j.1474-9726.2012.00851.x 10.1093/nsr/nwaa041 10.1172/JCI140335 10.1038/s41591-020-0901-9 10.1007/s11357-020-00213-0 10.1016/j.autrev.2020.102537 10.1080/1744666x.2020.1750954 10.1038/s41577-020-0331-4 10.1016/j.lfs.2020.118102 10.1186/s41232-020-00131-w 10.1182/blood.2020007252 10.1038/s41590-017-0006-x 10.1007/978-3-319-99375-1_81 10.1007/978-3-319-99375-1_87 10.1126/science.abb0762 10.3389/fimmu.2020.00827 10.1146/annurev-cellbio-011620-034148 10.1111/acel.12326
Reviews in Endocrine & Metabolic Disorders; Oguz SH, Koca M et. al.

Apr 16th, 2021 - Coronavirus Disease 2019 (COVID-19) is characterized with a wide range of clinical presentations from asymptomatic to severe disease. In patients with severe disease, the main causes of mortality have been acute respiratory distress syndrome, cytokine storm and thrombotic events. Although all factors that may be associated with disease severity are not yet clear, older age remains a leading ris...

Biologic Treatment Algorithms for Moderate-to-Severe Psoriasis with Comorbid Conditions...
https://doi.org/10.1007/s40257-021-00603-w 10.1016/j.jaad.2016.07.064 10.1111/bjd.15610 10.1016/j.jaad.2017.10.012 10.1007/s40257-017-0328-3 10.3390/ijms18112297 10.1016/j.phrs.2019.104394 10.1016/j.jaad.2018.06.027 10.1016/j.jbspin.2017.11.001 10.1136/annrheumdis-2019-215386 10.1136/annrheumdis-2020-217372 10.1093/rheumatology/key161 10.1093/rheumatology/key182 10.1093/rheumatology/kez420 10.1002/acr.23111 10.1136/rmdopen-2018-000723 10.1016/S0140-6736(20)30564-X 10.1136/rmdopen-2019-000990 10.1007/s10067-018-3989-2 10.1016/S0140-6736(20)30265-8 10.1136/rmdopen-2020-001217 10.1016/S0140-6736(20)30265-8 10.1016/S0140-6736(20)30263-4 10.2147/OARRR.S56073 10.1002/art.40726 10.1016/j.autrev.2019.102429 10.1136/annrheumdis-2020-eular.3907 10.1038/JID.2015.350 10.1111/jdv.14705 10.1093/rheumatology/kes375 10.1136/annrheumdis-2015-208490 10.1001/jamaneurol.2020.1162 10.1016/j.crohns.2008.04.001 10.1001/archneurol.2009.11 10.1016/j.cyto.2008.11.002 10.1007/s00415-016-8128-x 10.1016/j.msard.2019.03.009 10.1111/1346-8138.14619 10.1111/ijd.14902 10.1111/jdv.16035 10.1016/S1474-4422(08)70173-X 10.1016/S0140-6736(08)60725-4 10.1111/bjd.12214 10.1111/bjd.16724 10.1016/S0140-6736(18)31713-6 10.1016/j.jaad.2016.11.042 10.1111/bjd.15750 10.1016/j.jaad.2016.11.041 10.1002/ejhf.113 10.1016/j.jaad.2013.09.020 10.2174/0929867322666150209160701 10.1016/j.ad.2012.02.003 10.3389/fimmu.2018.01668 10.7326/0003-4819-138-10-200305200-00008 10.1161/01.CIR.0000077913.60364.D2 10.1016/j.berh.2006.06.002 10.1016/j.jaad.2008.02.039 10.1007/s40257-019-00466-2 10.1080/09546634.2019.1603361 10.1016/j.jaad.2017.06.153 10.1056/NEJMoa1512711 10.1111/j.1365-2133.2012.10901.x 10.1111/bjd.13469 10.1136/rmdopen-2018-000763 10.1016/j.jid.2018.07.029 10.1016/j.jaad.2017.06.043 10.5114/aoms.2013.38670 10.1111/apt.15370 10.1093/ibd/izy322 10.1097/MIB.0000000000001072 10.1056/NEJMoa0904492 10.1093/ecco-jcc/jjz031 10.1136/gut.2010.221127 10.1007/s10620-015-4007-z 10.1136/annrheumdis-2018-214273 10.1016/j.jaad.2016.10.027 10.1038/ajg.2016.298 10.1111/apt.14794 10.1053/j.gastro.2018.06.035 10.14740/gr1194 10.1056/NEJMoa1900750 10.1016/S0140-6736(19)30952-3 10.1016/S0140-6736(19)31773-8 10.3748/wjg.v20.i43.16053 10.1007/s40257-019-00457-3 10.1016/j.jaad.2018.06.056 10.1016/j.jaad.2017.01.037 10.36849/JDD.2020.5138 10.2340/00015555-2989 10.1007/s40261-018-0671-z 10.1111/bjd.12461 10.1111/bjd.17444 10.1111/bjd.18232 10.1016/j.jaad.2013.08.049 10.3748/wjg.v21.i36.10274 10.1016/j.autrev.2015.01.011 10.1016/j.jaad.2008.03.023 10.1007/s10067-017-3916-y 10.1016/j.autrev.2008.07.011 10.1016/j.cmi.2017.12.025 10.1136/rmdopen-2019-000942 10.1136/bmjopen-2016-012567 10.1007/s13555-017-0198-x 10.1111/bjd.17084 10.1007/s12325-019-01145-8 10.1056/NEJMoa011110 10.1007/s13555-019-00340-3 10.1038/cti.2017.34 10.1016/j.jaad.2016.03.024 10.1111/j.1365-2133.2012.11142.x 10.1111/jdv.16460 10.1111/pde.13382 10.1016/j.jaad.2019.05.056 10.1080/09546634.2017.1364692 10.1016/j.jaad.2015.09.056 10.1056/NEJMoa066886 10.1111/jdv.15579 10.1016/S0140-6736(17)31189-3 10.1111/bjd.19147 10.1016/j.jaad.2015.07.002 10.1111/bjd.19018 10.23736/S0392-0488.18.06255-7 10.1080/09546634.2018.1468066 10.5114/ada.2020.96294 10.1002/pds.4930 10.1007/s40264-019-00881-8 10.1053/j.gastro.2016.05.061 10.1038/ajg.2013.171 10.1371/journal.pone.0223603 10.1136/annrheumdis-2017-212196 10.1002/art.40508 10.1136/annrheumdis-2017-211384 10.1159/000380880 10.1111/bjd.16901 10.1186/s13075-019-1882-2 10.1111/ajd.12641 10.1016/j.ijwd.2016.02.001 10.1111/jdv.12165 10.1111/j.1365-4632.2011.05310.x 10.1038/sj.jid.5700410 10.1038/jid.2009.113 10.1001/jamadermatol.2015.4847 10.1016/j.pharmthera.2007.10.001 10.1002/pds.2046 10.1016/j.jaad.2010.09.734 10.1136/ard.2010.149419 10.1016/j.jaad.2016.10.006 10.1001/2012.jama.10857 10.1016/S2468-1253(19)30362-0 10.1016/j.jaad.2016.09.026 10.1007/s40257-020-00512-4 10.1016/j.jaad.2011.06.041 10.1186/s13578-020-00404-4 10.1056/NEJMoa2034577 10.1016/j.jaad.2020.05.035 10.1016/j.jaad.2020.06.1014 10.1016/j.jaad.2020.03.031 10.1016/j.jdcr.2020.04.027 10.1007/s13555-020-00394-8 10.1001/jamadermatol.2015.0718 10.1016/j.jid.2017.10.005 10.1016/j.jaad.2018.04.012 10.1016/j.jaad.2018.04.013 10.1038/s41577-020-0328-z 10.1016/j.mehy.2020.109749 10.1016/j.jaad.2020.03.046 10.1001/jama.2020.2229 10.1111/bjd.15152 10.1016/S0140-6736(17)30068-5 10.1016/j.jaad.2016.12.014 10.1007/s00403-019-02024-6
American Journal of Clinical Dermatology; Thatiparthi A, Martin A et. al.

Apr 16th, 2021 - The emergence of data from clinical trials of biologics, the approval of new biologics, and our improved understanding of psoriasis pathogenesis have increased the therapeutic possibilities for the treatment of moderate-to-severe psoriasis. Biologics currently approved for the treatment of psoriasis include tumor necrosis factor inhibitors, interleukin (IL)-17 inhibitors, ustekinumab (an IL-12/...

Possible Mechanisms and Special Clinical Considerations of Curcumin Supplementation in ...
https://doi.org/10.1007/978-3-030-64872-5_11 10.1016/S0140-6736(20)30183-5 10.1016/S2665-9913(20)30120-X 10.1056/NEJM200005043421806 10.1007/s40291-016-0202-7 10.1002/biof.1344 10.1177/1535370214547156 10.1002/path.1491 10.1016/j.bbrc.2013.06.118 10.1128/MCB.17.9.5386 10.1016/S0167-5699(97)01197-3 10.1097/00024382-200208000-00001 10.1006/clim.1999.4693 10.1164/ajrccm/146.2.427 10.1007/978-3-319-63245-2_8 10.1186/s12967-020-02333-9 10.1080/22221751.2020.1732837 10.3201/eid1003.030571 10.1038/nri2711 10.1378/chest.09-1484 10.1016/j.ijpharm.2017.09.042 10.1016/j.ijpharm.2018.07.052 10.1016/j.jss.2011.11.1032 10.1177/0748233711430984 10.1016/S1521-6616(03)00042-1 10.1165/rcmb.2011-0175OC 10.1371/journal.pone.0057285 10.1007/s11130-016-0590-1 10.1208/s12248-012-9432-8 10.1016/j.biocel.2008.06.010 10.1080/10408398.2015.1077195 10.1158/1078-0432.CCR-04-0744 10.1158/1940-6207.CAPR-10-0098 10.1046/j.1365-2036.1999.00464.x 10.1046/j.1440-6047.2002.00296.x 10.1002/jcp.26249 10.1002/jcb.27192 10.1055/s-2004-827223 10.1016/j.bcp.2004.07.009 10.1021/acscentsci.0c00489 10.1186/1465-9921-7-125 10.1186/s12931-017-0553-6 10.1007/s00134-008-1235-0 10.1165/rcmb.2011-0392TR 10.5858/arpa.2013-0182-RA 10.1248/bpb.35.145 10.1007/s00228-007-0298-0 10.1124/dmd.106.011072 10.1080/00498254.2016.1183060 10.1055/s-0032-1328652 10.1016/j.clpt.2006.07.007 10.4142/jvs.2009.10.4.293 10.4062/biomolther.2011.19.3.364 10.1002/jps.22157 10.1016/j.ijpharm.2010.08.015 10.1016/j.dmpk.2016.02.005 10.1002/bdd.754 10.1038/srep06587 10.3892/ijo.2013.1995
Advances in Experimental Medicine and Biology; Heidari Z, Mohammadi M et. al.

Apr 16th, 2021 - The novel coronavirus outbreak caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was recognized in late 2019 in Wuhan, China. Subsequently, the World Health Organization declared coronavirus disease 2019 (COVID-19) as a pandemic on 11 March 2020. The proportion of potentially fatal coronavirus infections may vary by location, age, and underlying risk factors. However, acute...

Tachyarrhythmia as a possible symptom of coronavirus in a neonate diagnosed with transp...
https://doi.org/10.1111/jocs.15574
Journal of Cardiac Surgery; Lopez RA, Padilla LA et. al.

Apr 16th, 2021 - The coronavirus disease 2019 (COVID-19) pandemic poses broad challenges to healthcare systems and providers. The manifestations of this disease are still being described in a variety of different contexts and patient populations. We report the case of a neonate who demonstrated COVID-19 after surgical correction of transposition of the great arteries. In addition, the patient demonstrated an ev...

Pediatricians' COVID-19 experiences and views on the willingness to receive COVID-19 va...
https://doi.org/10.1080/21645515.2021.1896319
Human Vaccines & Immunotherapeutics; Gönüllü E, Soysal A et. al.

Apr 16th, 2021 - Developing an effective and safe vaccine against Covid-19 will facilitate return to normal. Due to hesitation toward the vaccine, it is crucial to explore the acceptability of the COVID-19 vaccine to the public and healthcare workers. In this cross-sectional survey, we invited 2251 pediatricians and 506 (22%) of them responded survey and 424 (84%) gave either nasopharyngeal swap or antibody ass...

COVID-19: An Organizational-theory-guided Holistic Self-caring and Resilience Project.
https://doi.org/10.1177/08980101211007007
Journal of Holistic Nursing : Official Journal of the Ame... Barnett P, Barnett M et. al.

Apr 16th, 2021 - Purpose: In response to the coronavirus disease 2019 (COVID-19) global human caring crisis, this article describes an innovative, theory-guided, holistic practice project at a major academic medical center in Northern California. The purpose of this theory-guided COVID-19 project was to address the self-care needs of caregivers so they could better care for patients/families who are confronting...

Finding of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) within Placenta...
https://doi.org/10.5858/arpa.2021-0076-LE
Archives of Pathology & Laboratory Medicine; Toto V, Tosi D et. al.

Apr 16th, 2021 - Finding of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) within Placental Tissue 11 Weeks after Maternal Infection.|2021|Toto V,Tosi D,De Vitis LA,Marconi AM,Bulfamante G,|

Efficacy of the BNT162b2 mRNA COVID-19 Vaccine in Patients with Chronic Lymphocytic Leu...
https://doi.org/10.1182/blood.2021011568
Blood Herishanu Y, Avivi I et. al.

Apr 16th, 2021 - Patients with chronic lymphocytic leukemia (CLL) have an increased risk for severe COVID-19 disease and mortality. The goal of this study (NCT04746092) was to determine the efficacy of COVID-19 vaccine in patients with CLL. We evaluated humoral immune responses to BNT162b2 mRNA COVID-19 vaccine in patients with CLL and compared responses with those obtained in age-matched healthy controls. Pati...

Fitted Filtration Efficiency of Double Masking During the COVID-19 Pandemic.
https://doi.org/10.1001/jamainternmed.2021.2033
JAMA Internal Medicine; Sickbert-Bennett EE, Samet JM et. al.

Apr 16th, 2021 - Fitted Filtration Efficiency of Double Masking During the COVID-19 Pandemic.|2021|Sickbert-Bennett EE,Samet JM,Prince SE,Chen H,Zeman KL,|

Impact of convalescent plasma therapy on SARS CoV-2 antibody profile in COVID-19 patients.
https://doi.org/10.1093/cid/ciab317
Clinical Infectious Diseases : an Official Publication Of... Tang J, Grubbs G et. al.

Apr 16th, 2021 - Convalescent plasma (CP) have been used for treatment of COVID-19, but their effectiveness varies significantly. Moreover, the impact of CP treatment on the composition of SARS-CoV-2 antibodies in COVID-19 patients and antibody markers that differentiate between those who survive and those who succumb to the COVID-19 disease are not well understood. Herein, we performed longitudinal analysis of...

Rehabilitation and COVID-19: update of the rapid living systematic review by Cochrane R...
https://doi.org/10.23736/S1973-9087.21.06995-1
European Journal of Physical and Rehabilitation Medicine; Andrenelli E, Negrini F et. al.

Apr 16th, 2021 - Rehabilitation and COVID-19: update of the rapid living systematic review by Cochrane Rehabilitation Field as of February 28th, 2021.|2021|Andrenelli E,Negrini F,de Sire A,Patrini M,Lazzarini SG,|

Automated detection of pneumonia cases using deep transfer learning with paediatric che...
https://doi.org/10.1259/bjr.20201263
The British Journal of Radiology; Salehi M, Mohammadi R et. al.

Apr 16th, 2021 - Pneumonia is a lung infection and causes the inflammation of the small air sacs (Alveoli) in one or both lungs. Proper and faster diagnosis of pneumonia at an early stage is imperative for optimal patient care. Currently, chest X-ray is considered as the best imaging modality for diagnosing pneumonia. However, the interpretation of chest X-ray images is challenging. To this end, we aimed to use...

International educators' attitudes, experiences, and recommendations after an abrupt tr...
https://doi.org/10.1152/advan.00241.2020
Advances in Physiology Education; Choate J, Aguilar-Roca N et. al.

Apr 16th, 2021 - The COVID-19 pandemic triggered university lockdowns, forcing physiology educators to rapidly pivot laboratories into a remote delivery format. This study documents the experiences of an international group of 10 physiology educators surrounding this transition. They wrote reflective narratives, framed by guiding questions, to answer the research question: "What were the changes to physiology l...

Pathologic Antibodies to Platelet Factor 4 after ChAdOx1 nCoV-19 Vaccination.
https://doi.org/10.1056/NEJMoa2105385
The New England Journal of Medicine; Scully M, Singh D et. al.

Apr 16th, 2021 - The mainstay of control of the coronavirus disease 2019 (Covid-19) pandemic is vaccination against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Within a year, several vaccines have been developed and millions of doses delivered. Reporting of adverse events is a critical postmarketing activity. We report findings in 23 patients who presented with thrombosis and thrombocytopenia ...