×
Characterization of m6 A modifications in the contemporary Zika virus genome and host c...
https://doi.org/10.1002/jmv.27869
Journal of Medical Virology; Liu Y, Li K et. al.

May 20th, 2022 - Zika virus (ZIKV) suddenly evolved from a neglected arthropod-borne flavivirus into a pandemic pathogen during 2015-2016. A panel of amino acid mutations have been shown to be responsible for the enhanced neurovirulence and transmissibility of ZIKV. Recent studies have demonstrated that ZIKV genomic RNA is modified by host N6-methyladenosine (m6 A) machinery during viral replication in host cel...

Estimates of COVID-19 vaccine uptake in major occupational groups and detailed occupati...
https://doi.org/10.1002/ajim.23370
American Journal of Industrial Medicine; Henneberger PK, Cox-Ganser JM et. al.

May 20th, 2022 - While other studies have reported estimates of COVID-19 vaccine uptake by broad occupational group, little is known about vaccine uptake by detailed occupational category. Data on COVID-19 vaccination were provided by US adults ages ≥18 years old who responded to the Facebook/Delphi Group COVID-19 Trends and Impact Survey (Delphi US CTIS) in April-May 2021, reported working for pay in the past ...

Examining the psychological and financial impact of travel restrictions on citizens and...
https://doi.org/10.1136/bmjopen-2021-059922
BMJ Open; McDermid P, Craig A et. al.

May 20th, 2022 - This study aimed to evaluate the psychological and financial distress reported by citizens and permanent residents stranded abroad due to international travel restrictions introduced in response to the COVID-19 pandemic. An international cross-sectional study. A primary analysis of data collected between July and September 2021 through an online survey targeting individuals stranded abroad and ...

Improving patient and clinician safety during COVID-19 through rapidly adaptive simulat...
https://doi.org/10.1136/bmjopen-2021-058980
BMJ Open; Evans LV, Ray JM et. al.

May 20th, 2022 - COVID-19 required healthcare systems to iteratively adapt for safe and up-to-date care as knowledge of the disease rapidly evolved. Rates of COVID-19 infections continue to fluctuate and patients without COVID-19 increasingly return to the emergency department (ED) for care. This leads to new challenges and threats to patient and clinician safety as suspected patients with COVID-19 need to be q...

Pandemic impact on patients with advanced non-COVID-19 illness and their family carers ...
https://doi.org/10.1136/bmjopen-2021-059577
BMJ Open; Nyblom S, Benkel I et. al.

May 20th, 2022 - To investigate the experiential impact of the COVID-19 pandemic on patients with non-COVID, life-threatening disease and their family carers. An interpretative qualitative design informed by phenomenological hermeneutics and based on data from in-depth interviews, performed between June and September 2020. Patients receiving specialised palliative home care and their family carers living in Swe...

Effect of the COVID-19 Pandemic on Kidney Transplant and on Chronic Dialysis Patients.
https://doi.org/10.1016/j.transproceed.2022.02.061
Transplantation Proceedings; Amsei TQM, Gorayeb-Polacchini FS et. al.

May 20th, 2022 - The reported fatality rates of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in patients receiving maintenance dialysis or kidney transplant are higher than in the general population. The aim of this study was to evaluate the impact of SARS-CoV-2 infection in chronic dialysis patients (DPs) compared with kidney transplant recipients (KTxRs). A study evaluating 266 COVID...

Worldwide Disparities in Recovery of Cardiac Testing 1 Year Into COVID-19.
https://doi.org/10.1016/j.jacc.2022.03.348
Journal of the American College of Cardiology; Einstein AJ, Hirschfeld C et. al.

May 20th, 2022 - The extent to which health care systems have adapted to the COVID-19 pandemic to provide necessary cardiac diagnostic services is unknown. The aim of this study was to determine the impact of the pandemic on cardiac testing practices, volumes and types of diagnostic services, and perceived psychological stress to health care providers worldwide. The International Atomic Energy Agency conducted ...

Unbiased COVID-19 Pandemic With Biased Global Recovery.
https://doi.org/10.1016/j.jacc.2022.03.350
Journal of the American College of Cardiology; Al-Mallah M, Naqvi TZ

May 20th, 2022 - Unbiased COVID-19 Pandemic With Biased Global Recovery.|2022|Al-Mallah M,Naqvi TZ,|

Acute interstitial nephritis after COVID-19 vaccination.
https://doi.org/10.1136/bcr-2021-246841
BMJ Case Reports; Tan FS, Kabir ME et. al.

May 20th, 2022 - A woman in her 70s presented to the hospital being generally unwell 8 days following the first dose of the AstraZeneca COVID-19 vaccination. She was in stage III acute kidney injury (AKI) with hyperkalaemia and metabolic acidosis. Urinalysis showed haematoproteinuria. Renal immunology screen was negative. She subsequently underwent two renal biopsies. The second biopsy showed features consisten...

Vaccine-induced immune thrombocytopaenia and thrombosis (VITT) after COVID-19 vaccination.
https://doi.org/10.1136/bcr-2021-247346
BMJ Case Reports; Ribeiro MI, Pimenta I et. al.

May 20th, 2022 - COVID-19 represents a global health emergency, causing significant morbidity and mortality. Multiple vaccines have been distributed worldwide to control the spread of this pandemic. Several reports of thrombosis and thrombocytopaenia have been described after vaccination. These have been termed vaccine-induced immune thrombocytopaenia and thrombosis (VITT). We report a fatal case of VITT after ...

Gynecologic Cancer Studies: What to Look for at ASCO 2022
https://www.medscape.com/viewarticle/973898

May 20th, 2022 - This transcript has been edited for clarity. I'm Maurie Markman from Cancer Treatment Centers of America. I would like to briefly comment on the abstracts that have been released for the American Society of Clinical Oncology (ASCO) meeting coming up next month in Chicago and specifically the gynecologic oncology track. It's going to be a very interesting series of sessions. There's an oral abst...

Africa Has Contained Monkey Pox Outbreaks During COVID Pandemic: Africa CDC
https://www.medscape.com/viewarticle/974259

May 20th, 2022 - JOHANNESBURG (Reuters) - Several outbreaks of monkey pox in Africa have been contained during the COVID pandemic while the world's attention was elsewhere, and outbreaks in Europe and the United States are a concern, Africa's top public health agency said on Thursday. A handful of cases of the virus, which causes fever symptoms and a distinctive bumpy rash, have been reported or are suspected i...

EU Health Regulator Backs Using AstraZeneca COVID Shot as Booster
https://www.medscape.com/viewarticle/974272

May 20th, 2022 - LONDON (Reuters) - The European health regulator on Thursday endorsed the use of AstraZeneca's COVID vaccine, Vaxzevria, as a booster. The recommendation, made by a committee of the European Medicines Agency (EMA), encompasses adults who have either been previously vaccinated by Vaxzevria or an mRNA vaccine, such as the ones made by Pfizer and BioNTech or Moderna. The recommendation comes weeks...

US CDC Says COVID Vaccine-Related Myocarditis Much Lower for Children Than Teens
https://www.medscape.com/viewarticle/974285

May 20th, 2022 - NEW YORK (Reuters) - The U.S. Centers for Diseases Control and Prevention (CDC) on Thursday said rates of reported heart inflammation linked to the Pfizer/BioNTech COVID-19 vaccine have been much lower in 5- to 11-year-old boys than in adolescents and young men, and were only slightly elevated above normal. The agency, in a presentation to an advisory committee discussing on the need for booste...

Siga Gets Requests for Smallpox Drug in Europe as Monkeypox Spreads
https://www.medscape.com/viewarticle/974283

May 20th, 2022 - (Reuters) - Siga Technologies Inc has received requests for the use of its smallpox drug to treat monkeypox, its chief executive officer told Reuters on Thursday, as cases spread in parts of Europe. There had been no deliveries yet but the company was "well-positioned" in terms of supply, CEO Phil Gomez said. The drug, tecovirimat (TPOXX; ST-246), was approved in 2018 to treat smallpox in the U...

Desktop 'Air Curtains' May Deflect Virus Particles
https://www.medscape.com/viewarticle/974315

May 20th, 2022 - (Reuters) - When people cannot maintain a safe distance to avoid the spread of COVID-19, a newly designed desktop "air curtain" can block aerosols in exhaled air, researchers found. Air-curtains - artificially created streams of moving air - are often used to protect patients in operating rooms. At Nagoya University in Japan, researchers tested their new desktop device by simulating a blood col...

Famotidine Aids in COVID-19 by Helping Limit Inflammation
https://www.medscape.com/viewarticle/974316

May 20th, 2022 - (Reuters) - Researchers have discovered just how the antacid famotidine, commonly sold as Pepcid by a Johnson & Johnson unit, was able to help alleviate COVID-19 symptoms in clinical trials. In studies in mice, they found that famotidine stimulates the vagus nerve, which controls the immune system and other involuntary body functions. When the vagus nerve is stimulated, it can send out signals ...

SARS-CoV-2 Could Be at Root of Mysterious Hepatitis in Kids
https://www.medscape.com/viewarticle/974318

May 20th, 2022 - (Reuters) - A chain of events possibly triggered by unrecognized infection with the SARS-CoV-2 coronavirus could be causing the mysterious cases of severe hepatitis reported in hundreds of young children around the world, researchers suggest. Children with COVID-19 are at significantly increased risk for liver dysfunction afterward, according to a report posted on Saturday on medRxiv ahead of p...

Fever After a Tropical Trip: A Guide to Differential Diagnosis
https://www.medscape.com/viewarticle/974364

May 20th, 2022 - After 2 years of a pandemic in which traveling was barely possible, tropical diseases are becoming important once more. At this year's conference for internal medicine specialists, tropical medicine specialist Fritz Holst, MD, of the Center for Tropical and Travel Medicine in Marburg, Germany, explained what questions you should be asking travelers with a fever at your practice and how to proce...

How to Manage Drug Interactions With Paxlovid for COVID
https://www.medscape.com/viewarticle/974399

May 20th, 2022 - Editor's note: Find the latest COVID-19 news and guidance in Medscape's Coronavirus Resource Center. Misinformation about nirmatrelvir/ritonavir (Paxlovid, Pfizer) for treating mild-to-moderate COVID-19 in patients at high risk for severe disease is feeding misunderstanding among prescribers and patients, two experts from the Infectious Diseases Society of America (IDSA) said on Friday. They br...