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About 15,388 results

Pediatric Epilepsy Study
https://clinicaltrials.gov/ct2/show/NCT00050934

Nov 22nd, 2011 - This study will evaluate the safety and effectiveness of oxcarbazepine (Trileptal) as add-on therapy in the treatment of partial seizures in pediatric patients 1 month to 3 years of age.

Interleukin-2 Plus Histamine Dihydrochloride in Treating Patients With Acute Myeloid Leukemia
https://clinicaltrials.gov/ct2/show/NCT00003991

Nov 5th, 2013 - OBJECTIVES: I. Compare the efficacy of interleukin-2 plus histamine dihydrochloride (Maxamine) vs no further therapy in prolonging the leukemia free survival in patients with acute myeloid leukemia in first or subsequent complete remission (CR) following consolidation therapy. II. Compare the relapse rate, overall survival, and quality of life in this patient population treated with interleukin...

Interleukin-2 in Treating Patients With Metastatic Kidney Cancer
https://clinicaltrials.gov/ct2/show/NCT00018941

Jun 16th, 2013 - OBJECTIVES: I. Determine the response rate and overall survival of patients with metastatic renal cell carcinoma treated with either low-dose or high-dose intravenous interleukin-2 (IL-2) or subcutaneous IL-2. II. Compare the toxic effects of these 3 regimens in this patient population. OUTLINE: This is a randomized study. Patients are stratified according to presence of renal tumor (yes vs no)...

Pharmacotherapy and Intensive Treatment - 2
https://clinicaltrials.gov/ct2/show/NCT00000218

Jan 11th, 2017 - The purpose of this study is to evaluate desipramine and carbamazepine in reducing cocaine craving; increase outpatient treatment capacity and evaluate their incidence of psychiatric disorders.

Behavior and Naltrexone Treatment for Alcoholics
https://clinicaltrials.gov/ct2/show/NCT00000449

Jun 23rd, 2005 - The study's purpose is to improve alcoholism treatment by investigating the combined effectiveness of a psychotherapy (Coping Skills Training and Cue Exposure Treatment - CSTCET) with naltrexone in a randomized clinical trial. Individuals will receive 2 weeks of CSTCET or a control treatment as inpatients followed by 12 consecutive weeks of receiving either naltrexone or placebo as outpatients....

Vaccine Therapy With or Without Interleukin-2 in Treating Patients With Metastatic Melanoma
https://clinicaltrials.gov/ct2/show/NCT00019448

Jun 19th, 2013 - OBJECTIVES: I. Determine the clinical response of patients receiving DNA gp100 antigen alone or in combination with interleukin-2 for recurrent metastatic melanoma. II. Identify the immunologic response in these patients prior to and after these treatments. III. Determine the toxicity of these treatments in these patients. PROTOCOL OUTLINE: Patients are accrued for the first three cohorts and t...

Efficacy of Nonsteroidal Anti-inflammatory Drugs in Treatment of Moderate and Severe Dry Eye Disease
https://clinicaltrials.gov/ct2/show/NCT01562795

Jan 2nd, 2014 - This clinical trial is to investigate whether nonsteroid anti-inflammatory drops have therapeutic effect on moderate to severe dry eye patients.And compare the efficacy of the two nonsteroid anti-inflammatory drops with topical corticosteroids.

Effect of Affective Content on Drug Induced Amnesia of Episodic Memory
https://clinicaltrials.gov/ct2/show/NCT00142493

Dec 23rd, 2015 - The protocol "Effect of Affective Content on Drug Induced Amnesia of Episodic Memory" investigates the relationship between the ability of affective ('emotional') content to modulate the formation of episodic memory, and the memory impairment ('amnestic') effects of several common intravenous anesthetic drugs. Because memory modulation by affective content appears to be a distinct memory proces...

Comparing Nitrous Oxide and Carbon Dioxide for Laparoscopic Cholecystectomy
https://clinicaltrials.gov/ct2/show/NCT01512511

Jan 18th, 2012 - There is no general agreement about the ideal gas for pneumoperitoneum. CO2, now in common use, has not compared to N2O sufficiently to disclose which one has minimal "physiological" invasiveness characters. Assigned randomly to carbon dioxide or nitrous oxide group, the hemodynamic and respiratory parameters (heart rate, mean arterial blood pressure, end-tidal CO2, minute ventilation, and O2 s...

Apremilast for Chronic Plaque Psoriasis (CPP) Patients Who Have Failed One Course of Biologic Therapy
https://clinicaltrials.gov/ct2/show/NCT01200264

Jul 14th, 2014 - Data Analysis Data will be analyzed and reported after all subjects have completed follow-up phase of study. All subsequent data collected will be analyzed and reported in a follow-up clinical report. Data & Safety Monitoring Dr. Murray will be following all laboratory values and adverse events during this trial. In addition, Celgene will provide a study monitor to, at regular intervals, review...

A Comparison of Safety and Treatment in Subjects With Osteoarthritis Taking Low Dose Aspirin
https://clinicaltrials.gov/ct2/show/NCT00175032

Jul 21st, 2010 - This study was designed to compare the effectiveness of reducing the incidence of gastroduodenal ulcers between lansoprazole 30mg QD + naproxen 500mg BID vs celecoxib 200mg QD in subjects with osteoarthritis taking low dose aspirin. Approximately 100 sites across the U.S. will enroll subjects with normal endoscopic findings and negative H.pylori. The duration of the study will be a maximum of 1...

Efficacy of Tinoridine in Treating Pain and Inflammation in Adults
https://clinicaltrials.gov/ct2/show/NCT01224756

Jan 11th, 2012 - Tonsillitis and pharyngitis are the most common upper respiratory tract infections. The signs and symptoms are sore throat, difficulty with swallowing and/or inflamed tonsils and/or pharynx. In most cases these infections are viral in origin. Tinoridine is a nonsteroid anti-inflammatory drug with a different mechanism of action than common nonsteroidal anti-inflammatory drugs (NSAIDs), which ac...

Study Evaluating the Safety and Efficacy of Etanercept in Patients With Idiopathic Pulmonary Fibrosis
https://clinicaltrials.gov/ct2/show/NCT00063869

Sep 3rd, 2009 - The objective of the study is to evaluate the safety and efficacy of etanercept in comparison with placebo in a double-blind, parallel, randomized fashion in subjects with idiopathic pulmonary fibrosis (IPF) who failed previous therapy. The treatment period will be up to 1 year. The primary objective is evaluation of safety and efficacy. Secondary: The secondary objective is to evaluate quality...

Celecoxib in Treating Patients With Cervical Intraepithelial Neoplasia
https://clinicaltrials.gov/ct2/show/NCT00081263

Sep 14th, 2017 - PRIMARY OBJECTIVES: I. To determine the efficacy of celecoxib to induce complete remission (or partial regression to cervical intraepithelial neoplasia (CIN) 1) of CIN 2/3 or CIN 3 as evaluated in the post-treatment excisional biopsy. II. To determine the toxicity of celecoxib (400 mg once daily) as assessed by Common Terminology Criteria for Adverse Events in this patient population of women w...

Study to Determine if Taking OTC Non-Steroidal Anti-Inflammatory Affects Eye Pressure in Patients Using Glaucoma Drops
https://clinicaltrials.gov/ct2/show/NCT00402493

Apr 3rd, 2018 - Topical IOP-lowering therapy has the advantage of providing a drug level directly to the end organ with very little or no systemic absorption thereby reducing side effect potential. There is very little information in the ophthalmic literature regarding potential drug interactions between topical IOP-lowering medications and other medications taken orally for other medical reasons. Patients wil...

Role of Endorphins in the Perception of Dyspnea in Patients With Chronic Obstructive Pulmonary Disease
https://clinicaltrials.gov/ct2/show/NCT00458419

Nov 1st, 2007 - Endorphins are naturally occurring narcotic substances that are released when individuals perform exercise. The hypothesis of the study is that endorphins reduce the severity of breathlessness during exercise in patients with chronic obstructive pulmonary disease (COPD). The initial five visits include familiarization and validation of a computerized system for patients to report dyspnea and le...

Rivaroxaban in Combination With Aspirin Alone or With Aspirin and a Thienopyridine in Patients With Acute Coronary Syndromes (The ATLAS ACS TIMI 46 Trial)
https://clinicaltrials.gov/ct2/show/NCT00402597

Oct 3rd, 2012 - This is a randomized (patients will be assigned to study treatment by chance), double-blind (neither the patient nor the study doctor will know the identity of the assigned study treatment) study to evaluate the safety and efficacy of rivaroxaban (study drug) compared to placebo (a tablet identical in appearance to study drug but contains no active drug) in patients with acute coronary syndrome...

Testing The Effectiveness Of Celecoxib In Patients With Painful Sore Throat
https://clinicaltrials.gov/ct2/show/NCT00402987

Jun 10th, 2009 - We are proposing a study in which we utilize and augment the sore throat pain model to assess the analgesic effectiveness of celecoxib compared to placebo in patients with painful pharyngitis under randomized, double-blind, placebo-controlled conditions.

A Clinical Study in Children and Adolescents With Mild to Moderate Atopic Dermatitis
https://clinicaltrials.gov/ct2/show/NCT00568412

Feb 17th, 2015 - To show therapeutic efficacy of Zarzenda cream compared to Elidel cream in children and adolescents with mild to moderate atopic dermatitis

Comparison of the Efficacy of Topical Ibuprofen to Oral Ibuprofen in Adolescent Athletes
https://clinicaltrials.gov/ct2/show/NCT00567528

Jan 13th, 2015 - This study was made to compare the efficacy of topical ibuprofen in gel form with oral ibuprofen in the treatment of sub-acute soft tissue injuries while comparing the tolerability of the delivery methods