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About 10,436 results

Study of Levalbuterol, Racemic Albuterol and Placebo in Subjects Twelve Years of Age and Older With Asthma
https://clinicaltrials.gov/ct2/show/NCT00073827

Feb 21st, 2012 - This was a Phase III, multicenter, randomized, double-blind, placebo- and active-controlled, parallel-group study of up to 9 weeks in duration. Seven days of QID single-blind placebo administration (via MDI) was followed by 56 days of QID double-blind active treatment. Following the run-in period, each subject was randomized to one of the following three treatments: levalbuterol HFA MDI 90 mcg ...

Recombinant Human C1 Inhibitor for the Treatment of Acute Attacks in Patients With Hereditary Angioedema
https://clinicaltrials.gov/ct2/show/NCT00262301

Oct 1st, 2012 - A prospectively planned interim analysis will be performed on the double-blind data.

Effect of a Component of Fish Oil on Exercise-Induced Bronchoconstriction and Airway Inflammation in Asthma
https://clinicaltrials.gov/ct2/show/NCT01200446

May 25th, 2011 - To date, fish oil supplementation studies in patients with asthma have used a combination of omega-3 polyunsaturated fatty acids. A study on the specific formula that is most effective in preventing exercise-induced bronchoconstriction (EIB) has yet to be conducted in humans. Nevertheless, it has been shown that a docosahexaenoic acid (DHA) metabolite, protectin D1, is involved in the active re...

Nasal Ocular Reflexes Contribute to Eye Symptoms
https://clinicaltrials.gov/ct2/show/NCT00117832

Sep 4th, 2013 - Symptoms of conjunctivitis (tearing, redness and itching) frequently occur in patients with allergic rhinitis. The pathophysiology underlying these symptoms remains to be elucidated. The symptoms probably arise via a combination of mechanisms including direct contact of natural pollen with the conjunctiva and reflex mechanisms originating in the nose. Pollen exposure can result from direct hand...

Collaborative Studies on the Genetics of Asthma (CSGA)
https://clinicaltrials.gov/ct2/show/NCT00005500

Oct 23rd, 2017 - BACKGROUND: Asthma is a respiratory disease characterized by variable airways obstruction, airways inflammation and bronchial hyperresponsiveness (BHR). There are recent increases in asthma mortality and prevalence in the US, especially in African-Americans. Multiple studies suggest that both genetic and environmental factors are important in asthma susceptibility. The study was recommended by ...

A European Post-Authorisation Observational Study Of Patients With Hereditary Angioedema
https://clinicaltrials.gov/ct2/show/NCT01541423

Oct 23rd, 2016 - This observational (non-interventional) study is being conducted to characterize the safety and use of CINRYZE in routine clinical practice when administered for (1) routine prevention of angioedema attacks, (2) pre-procedure prevention of angioedema attacks, and/or (3) treatment of angioedema attacks.

Airway Inflammatory Profile Among Cleaning Workers From Different Workplaces
https://clinicaltrials.gov/ct2/show/NCT03311048

Mar 29th, 2018 - Were recruited to participate in the study individuals from four different workplaces: Hospital; University; Housekeeper and Control (office workers). The research was performed in Cacoal city, Rondonia, Brazil. Smokers (active), pregnant, lactating, and individuals at continuing therapy for treating disorders of the airways were excluded. Clinical profile and respiratory symptoms employees eva...

Study of a Topical Nasal Spray to Ease the Symptoms of Hayfever
https://clinicaltrials.gov/ct2/show/NCT01500629

Feb 26th, 2017 - This study is a randomized, double blind, placebo-controlled, 2-way cross over trial. Approximately 25 subjects with a history of seasonal grass and/or ragweed allergy symptoms will be enrolled in the study to ensure 20 complete the study. Subjects will be randomized to one of two treatment sequences of experimental product (investigational nasal spray) and placebo (sham nasal spray). Subjects ...

Study of the Efficacy and Tolerance of Light Therapy in Sensitive Skin
https://clinicaltrials.gov/ct2/show/NCT03279003

Sep 11th, 2017 - The objective of the study is to evaluate the efficacy of light-emitting diode therapy in subjects with sensitive skin and to assess pain improvement, evaluation of improvement in pruritus and evaluation of treatment tolerance.

Effect of the Nasal Provocation on the Breathing Style
https://clinicaltrials.gov/ct2/show/NCT02146300

It is intended to clarify on both healthy and birch pollen allergic adults how the provocation of the nose with the birch pollen, dilutant and xylometazoline affect the breathing style (breathing pattern) and how these possible changes could be controlled in the measurement of the breathing with respiratory effort belts. In addition to this, our intention is to clarify the effect of the facial ...

A Study to Evaluate the Safety and Effectiveness of a Nasal Spray to Treat Seasonal Allergies
https://clinicaltrials.gov/ct2/show/NCT00824473

Feb 22nd, 2010 - The purpose of this study is to determine if one allergy medication (0.15% azelastine hydrochloride) is more effective than Placebo alone

Improving Nutrient Intake and Growth in Children With Multiple Food Allergies
https://clinicaltrials.gov/ct2/show/NCT01571830

Aug 5th, 2015 - This is a prospective observational study with repeated measure design. All participants aged 6 months to 6 years diagnosed with two or more food allergies will be invited to participate in the research study. At least one of the two food allergies must be milk, egg, wheat, or soy, which are nutritionally important food allergies. Inclusion criteria include diagnosis of two or more food allergi...

Effects of Preventive Treatment for Respiratory Syncytial (RS) Virus Infection During Infancy on Later Atopic Asthma in Preterm Infants
https://clinicaltrials.gov/ct2/show/NCT01545245

Dec 7th, 2014 - The primary objective of the study is to determine whether the incidence of atopic asthma after three years old may be suppressed in the children who were born as preterm infants and prophylactically treated with palivizumab for respiratory syncytial (RS) virus infections during the infancy. The secondary objective is to determine whether the incidence of recurrent wheezing after three years ol...

Trial to Evaluate the Effect of Statins on Asthma Control of Patients With Chronic Asthma
https://clinicaltrials.gov/ct2/show/NCT00126048

Mar 17th, 2010 - Statins are the most common type of cholesterol-lowering drugs used in clinical practice. Recent research suggests that they may also have anti-inflammatory properties, in particular by inhibition of an important inflammatory cell called a T lymphocyte. Asthma is characterised by chronic inflammation in the airways, which is thought to be regulated by the activity of T lymphocytes. The investig...

Ciclosporin Versus Alitretinoin for Severe Atopic Hand Dermatitis.
https://clinicaltrials.gov/ct2/show/NCT01231854

Jun 2nd, 2014 - The purpose of this study is to investigate the comparative efficacy, safety and efficiency of ciclosporin microemulsion and alitretinoin in adults with severe atopic hand dermatitis.

Exhaled Breath Condensate as a Measure of Airway Inflammation in Children With Asthma
https://clinicaltrials.gov/ct2/show/NCT00078208

Jul 1st, 2017 - The onset of asthma is often during childhood, and when the child is atopic, it is more likely to persist into adulthood. Diseases such as asthma have a higher prevalence in childhood; and management that alters the morbidity of allergic disease in children may impact disease outcomes in future years. Asthma is the most prevalent chronic disease in childhood and accounts for the highest rate of...

Maternal Fatty Acids, Child Obesity, and Asthma Immunity
https://clinicaltrials.gov/ct2/show/NCT00088257

Dec 12th, 2013 - BACKGROUND: Since most cases of asthma occur in the first few years of life, examining its pre- and early postnatal determinants is crucial. This study focuses on determinants of the developing immune system. T helper cells are of two types. Th1 cells participate in cell-mediated immunity essential for controlling intracellular infectious agents such as bacterial and viruses. Th2 cells are esse...

Internet-based Mindfulness and Exposure Treatment for Atopic Dermatitis
https://clinicaltrials.gov/ct2/show/NCT03051958

Feb 13th, 2017 - Atopic dermatitis (AD) is highly prevalent and leads to suffering for the individual, increased risk of depressive symptoms and anxiety, and high societal costs. A few psychological treatment have been tested for AD, but to our knowledge none of them have been built on recently developed methods for optimizing exposure treatment. In addition, access to psychological treatment is limited and the...

Comparison Between Systemic Exposure to Ciclesonide Nasal Spray, Ciclesonide HFA Nasal Aerosol and Orally Inhaled Ciclesonide (BY9010/M1-422)
https://clinicaltrials.gov/ct2/show/NCT00458835

Dec 1st, 2016 - The purpose of this study is to compare the systemic des-ciclesonide exposure of OMNARIS™ (ciclesonide) nasal spray, ciclesonide HFA nasal aerosol, and orally inhaled ciclesonide HFA-metered-dose inhaler (MDI). The administration of the study medication will be as follows: three single doses, separated by a wash-out period. The study will provide further data on the safety and tolerability of c...

A Clinical Study in Children and Adolescents With Mild to Moderate Atopic Dermatitis
https://clinicaltrials.gov/ct2/show/NCT00568412

Feb 17th, 2015 - To show therapeutic efficacy of Zarzenda cream compared to Elidel cream in children and adolescents with mild to moderate atopic dermatitis