×
About 10,910 results

Selenium Supplementation of Patients With Cirrhosis
https://clinicaltrials.gov/ct2/show/NCT00212186

Mar 6th, 2012 - Selenium is an essential nutrient. Selenium carries out its biological functions through selenoproteins. The most abundant selenoprotein in the plasma is selenoprotein P, which is largely synthesized in the liver. Patients with liver disease often have less than half the selenoprotein P levels of normal individuals. This suggests that people with liver disease are not meeting their selenium req...

Sorafenib Tosylate in Treating Patients With Malignant Mesothelioma.
https://clinicaltrials.gov/ct2/show/NCT00107432

Jun 4th, 2013 - PRIMARY OBJECTIVES: I. To determine the response rate (partial response (PR) and complete response (CR)) in patients with malignant mesothelioma treated with BAY 43-9006. SECONDARY OBJECTIVES: I. To determine 3-month failure free survival in patients with malignant mesothelioma treated with BAY 43-9006. II. To describe the median and overall survival of malignant mesothelioma patients treated w...

Bioequivalency Study of Calcitriol Tablets Under Fasting Conditions
https://clinicaltrials.gov/ct2/show/NCT00601328

Jan 22nd, 2018 - The objective of this study was to assess the bioequivalence of Roxane Laboratories' Calcitriol capsules, 0.25 mcg, to ROCALTROL® capsules, 0.25 mcg (Roche) using a single-dose, 2-treatment, 2-period, crossover design, under fasting conditions

Sorafenib and Erlotinib or Sorafenib Alone in Advanced Non-Small Cell Lung Cancer Progressing on Erlotinib
https://clinicaltrials.gov/ct2/show/NCT00609804

Apr 7th, 2016 - This is a randomized, open-label, multi-center, Phase II study of treatment of patients with advanced NSCLC who have progressed on erlotinib with the combination of sorafenib and erlotinib or sorafenib alone.

Lacrimal Drainage System Obstruction Associated to Radioactive Iodine Therapy for Thyroid Carcinoma
https://clinicaltrials.gov/ct2/show/NCT01579344

The radioactive radioiodine therapy (Na131I) for the treatment of differentiated thyroid carcinoma is a procedure used for ablation of remaining thyroid tissue after thyroidectomy and metastases. Although serious complications are uncommon after treatment, there are well-documented adverse reactions secondary to the involvement of the salivary glands, such as dry mouth, pain in the parotid glan...

A Nutritional Intervention for Arthritis
https://clinicaltrials.gov/ct2/show/NCT01544101

Oct 18th, 2012 - Preliminary evidence suggests that low-fat, vegetarian diets and certain nutritional supplements can help reduce pain and also reduce the need for pain medications for some people. The investigators will ask about 100 people to participate. All of them will get a low-fat, vegan diet and a nutritional supplement (mixture of omega-3 oils and vitamin E or a placebo), although some will get the die...

Vitamin E and Male Infertility
https://clinicaltrials.gov/ct2/show/NCT00178516

Jul 29th, 2009 - Sperm DNA damage is an emerging cause of male infertility that is likely to be more common among men with increased reactive oxygen species in the ejaculate. Vitamin E can protect the sperm membrane from oxidative damage and increased levels are associated with low levels of reactive oxygen species. This is a study of Vitamin E levels in the spermatozoa and sera of 48 infertile men, and 20 fert...

The Use of Pentoxifylline and Vitamin E in the Treatment of Chronic Breast Pain
https://clinicaltrials.gov/ct2/show/NCT00188669

Aug 10th, 2010 - An estimated 20 - 45 % of women treated with breast conserving treatment experience chronic pain in the treated breast. The aetiology of this is poorly understood. Some of these women have signs of chronic radiation mastitis. There is no accepted treatment for this condition. The combination of pentoxifylline and vitamin E has been shown to be effective in reversing radiation fibrosis in this r...

Retinol Equivalence of Plant Carotenoids in Children
https://clinicaltrials.gov/ct2/show/NCT00082420

Jan 12th, 2010 - Seventy-two children each will take two meals, lunch and supper, containing equal amounts of ß-C in labeled spinach (along with white rice), or Golden Rice (along with light colored vegetables), or ß-C oil capsules (along with white rice and light colored vegetables), every day for 7 days. Before the two meals, the volunteers will take a breakfast with a RAc-d10 dose as a reference for 7 days. ...

Alvocidib, Oxaliplatin, Fluorouracil, and Leucovorin Calcium in Treating Patients With Advanced Solid Tumors
https://clinicaltrials.gov/ct2/show/NCT00080990

Dec 15th, 2013 - OBJECTIVES: I. Determine the maximum tolerated dose of flavopiridol when given in combination with oxaliplatin, fluorouracil, and leucovorin calcium in patients with advanced solid tumors. II. Determine the pharmacokinetics of this regimen in these patients. III. Determine, preliminarily, the therapeutic activity of this regimen in these patients. IV. Determine the dose-limiting toxicity and th...

Trial to Assess Vitamin D Requirements in Lactating Women
https://clinicaltrials.gov/ct2/show/NCT01349127

May 3rd, 2017 - This is a randomized, placebo-controlled trial of vitamin D supplementation with 20mcg cholecalciferol (to achieve a total intake of 25mcg/day), with or without 500mg calcium to assess vitamin D requirements in lactating women and to ascertain whether vitamin D supplementation at levels sufficient to achieve defined thresholds of maternal serum 25-hydroxyvitamin D will increase the vitamin D co...

Zinc & Bone Health in Thalassemia: The Think Zinc Study
https://clinicaltrials.gov/ct2/show/NCT00459732

Oct 6th, 2011 - The primary aim of this study is to determine if zinc supplementation improves bone health in young patients with thalassemia. Osteoporosis is a significant co-morbidity in patients with thalassemia which leads to decreased quality of life. The most effective way to prevent osteoporosis is to build strong, dense bones in the early years. A combination of disease, endocrine and nutritional facto...

EPI-743 for Mitochondrial Respiratory Chain Diseases
https://clinicaltrials.gov/ct2/show/NCT01370447

Jul 23rd, 2018 - This study evaluates the safety and efficacy of EPI-743 in patients with severe mitochondrial respiratory chain diseases who are considered to be within 90 days of end-of-life care.

SOLID-Effect of Risedronate Sodium at Distal Radius in Colle's Fracture.
https://clinicaltrials.gov/ct2/show/NCT00460733

Oct 3rd, 2011 - The purpose of this study is to evaluate the efficacy and safety of risedronate sodium (Actonel®) after a wrist fracture in postmenopausal women.

A Study to Evaluate Efficacy and Safety of Extended-Release Niacin + Laropiprant + Simvastatin in Participants With Primary Hypercholesterolemia or Mixed Dyslipidemia (MK-0524B-118)
https://clinicaltrials.gov/ct2/show/NCT01294683

Aug 15th, 2018 - This study is being done to find out if tablets containing extended release (ER) niacin, laropiprant, and simvastatin (ERN/LRPT/SIM) are as effective as tablets containing ER niacin and laropiprant taken with simvastatin tablets (ERN/LRPT + SIM) for lowering high cholesterol and high lipid levels in the blood. The primary hypothesis is that ERN/LRPT/SIM 2 g/40 mg is equivalent to ERN/LRPT 2 g c...

Effect of Vitamin D3 Supplementation on Muscle Mass in ICU Patient
https://clinicaltrials.gov/ct2/show/NCT02594579

There is a high prevalence of vitamin D deficiency in critically ill patient which is associated with muscle wasting and physical disability. Recent study showed that treatment of vitamin D deficiency with high dose vitamin D improved muscle wasting and may prevent further muscle breakdown. Investigator want to explore whether a high dose vitamin D3 supplementation, compare to placebo will be a...

Chemotherapy, Radiotherapy and Bevacizumab in Patients With Unresectable Stage III Non-Small-Cell Lung Cancer
https://clinicaltrials.gov/ct2/show/NCT00402883

Jan 12th, 2014 - The patients on this study will receive treatment in 3 stages of therapy. The first stage is Induction Therapy. This therapy is 7 weeks long. Patients will receive bevacizumab followed by pemetrexed followed by carboplatin all by vein once a week in weeks 1 and 4. During Induction patients will also receive radiation therapy daily, Monday through Friday, for 7 weeks (weeks 1-7). This is followe...

Oral Alfacalcidol and Coronary Artery Calcification in Predialysis Chronic Kidney Disease
https://clinicaltrials.gov/ct2/show/NCT01364688

Active vitamin D compound is used frequently in the treatment of hyperparathyroidism in chronic kidney disease. Recent evidence from animal studies suggested that low dose of active vitamin D may be protective against vascular calcification, whereas high dose could precipitate it. The present study will examine the effect of low dose oral alfacalcidol on coronary artery calcification in predial...

Venavine Intensive® in the Treatment of Symptoms Associated With Chronic Venous Insufficiency
https://clinicaltrials.gov/ct2/show/NCT02483962

May 18th, 2016 - This study is a 90 day, match paired, double-blinded, placebo-controlled study involving forty females participants between the ages of 30 and 55. Participants will be recruited via advertisements placed at the University of Johannesburg (UJ) Health Centre and on the campus. This sample group will be shared with another Homoeopathy Masters student, Xoliswa Mazibuko, who will be evaluating the c...

Phase I/II Trial of RAD001 Plus Nexavar in Patients With Kidney Cancer
https://clinicaltrials.gov/ct2/show/NCT00448149

Mar 16th, 2016 - Despite significant progress in understanding the biology of renal cell carcinoma (RCC), it is estimated that over 35, 000 people in the United States will be diagnosed and approximately 12, 000 have died from this disease in 2005. Renal cell carcinoma presently ranks tenth as the leading cause of cancer death and constitutes 3% of all solid neoplasms. In contrast to many other malignancies, tr...