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About 30,190 results

Impact of Mesenchymal Stem Cells in Knee Osteoarthritis
https://clinicaltrials.gov/ct2/show/NCT03477942

Sep 10th, 2021 - Many patients with osteoarthritis of the knee fail non-operative measures and elect to have knee arthroplasty to improve their quality of life. If successful, intra-articular mesenchymal stem cell (MSC) injections into the knee may offer another viable non-operative treatment modality. Additionally, this modality may have reparative or regenerative potential, which could lead to the first treat...

Lokal Cold Application in Nitroglycerin-Induced Headache (NIH)
https://clinicaltrials.gov/ct2/show/NCT04707586

Sep 10th, 2021 - The study was planned to evaluate the effect of local cold application on headache severity in individuals who received intravenous nitroglycerin treatment, which mostly causes headache due to its vasoditator effect. Inclusion criteria; The patient's volunteerism to participate in the research, Over the age of 18, Being conscious, Any analgesic, NSAID, triptan etc. Not taking antimigren drugs o...

Novel Multimodal Pain Control Protocol for Minimally Invasive Gynecologic Surgery
https://clinicaltrials.gov/ct2/show/NCT04710277

Sep 10th, 2021 - The study is a randomized controlled trial investigating a multimodal postoperative pain management protocol which will include use of ice therapy and scheduled opioid-sparing medications for pain control after minimally invasive gynecologic surgery. The study will include women >/= 18yo who speak English and are admitted for observation after a qualifying laparoscopic or robotic gynecologic pr...

Differential Target Multiplexed Spinal Cord Stimulation (DTM-SCS®) Real World Outcomes
https://clinicaltrials.gov/ct2/show/NCT04725838

Sep 10th, 2021 - This clinical investigation is a prospective, observational, open-label, non-randomized, multi-center study. It is designed to collect clinical follow-up data on Differential Target Multiplexed (DTM®) programming that is available in Medtronic's Intellis™ spinal cord stimulator, which has shown superiority to conventional programming parameters in a randomized controlled trial (NCT03606187). Pa...

SCS as an Option for Chronic Low Back and/or Leg Pain Instead of Surgery
https://clinicaltrials.gov/ct2/show/NCT04676022

Sep 10th, 2021 - To evaluate the safety and effectiveness of Spinal Cord Stimulation (SCS) with multiple modalities compared to Conventional Medical Management (CMM) in patients with chronic low back and/or leg pain who have not undergone spinal surgery when using the Boston Scientific WaveWriter SCS Systems.

Modified TAP (Transverse Abdominis Plane) Block in Colorectal Surgery
https://clinicaltrials.gov/ct2/show/NCT04781075

Sep 10th, 2021 - Subjects recruited into the study will undergo surgery as scheduled. During the procedure they will receive a TAP Block with one of the pain medications. TAP Block in the experimental arm will be performed with 20 mL (266mg) of liposomal bupivacaine with 25 mL (5 mg/mL) of bupivacaine diluted in 55 mL of normal saline. The control arm will have a TAP Block performed with 30 mL (5mg/mL) of bupiv...

Premedication With Intranasal Dexmedetomidine in Sedation of Patients Undergoing Total Knee Arthroplasty
https://clinicaltrials.gov/ct2/show/NCT04859283

Sep 10th, 2021 - Patients undergoing total knee arthroplasty (TKA) under spinal anesthesia often request sedation to alleviate anxiety. Dexmedetomidine may be ideally suited to provide sedation during surgery as it offers sedation and analgesia without causing significant respiratory depression. Furthermore, dexmedetomidine has beneficial synergistic interactions with opioids and sedative drugs. Altogether 80 p...

Lifestyle in Adolescence and Persistent Musculoskeletal Pain in Young Adulthood
https://clinicaltrials.gov/ct2/show/NCT04575974

Sep 10th, 2021 - There is need for knowledge on modifiable risk factors for MSK pain in young ages to better target treatment and preventive. A combination of lifestyle factors has been associated with several health issues including MSK pain in adults, but has to the best of our knowledge not previously been investigated as a risk factor for MSK pain in the youth. OBJECTIVE The objective of this study is to in...

Combining Mechanisms for Better Outcomes (COMBO)
https://clinicaltrials.gov/ct2/show/NCT03689920

Sep 10th, 2021 - To evaluate the effectiveness of Spinal Cord Stimulation (SCS) with multiple modalities as compared to conventional SCS in patients with chronic pain when using the Boston Scientific Spectra WaveWriter SCS System.

Effectiveness of Education and Relaxation Program on Migraine Related Disability in Patients Attending Headache Clinic
https://clinicaltrials.gov/ct2/show/NCT05039996

Sep 10th, 2021 - - The participants will be assessed for their eligibility based on inclusion and exclusion criteria. After obtaining the written informed consent, the eligible participants will be randomized to either an intervention or a control group. Psychiatric and personality disorders will be excluded before participation using the translated form of (Structured Clinical Interview for the Diagnostic and ...

Home Blood Pressure Monitoring Before and After COVID-19 Vaccination in Patients at High Risk of Cardiovascular Disease
https://clinicaltrials.gov/ct2/show/NCT05033613

Sep 10th, 2021 - The coronavirus SARS-CoV-2 causing COVID-19 was pandemic since 2020. Vaccination is one of the most important measure to control the outbreak. The countries of the world started the vaccination since December, 2020. Taiwan started since March, 21st, 2021. Currently, Taiwanese people receive COVID-19 vaccination by either AZ or Moderna; Pfizer/BNT vaccine may import in the near future. The side ...

Feasibility of Olive Oil for Reducing Facial Pain of Trigeminal Neuralgia
https://clinicaltrials.gov/ct2/show/NCT05032573

Sep 10th, 2021 - Trigeminal neuralgia (TGN) pain is debilitating and unpredictable. Alleviation of intensity or frequency to any degree will improve the quality of life of the individuals affected. Current medical treatments for TGN are often not effective. In some cases, the pain is a result of myelin degeneration. If diet can provide the basic building blocks for myelin regrowth, then the investigators may be...

Sensorimotor Control in People With and Without Neck Pain
https://clinicaltrials.gov/ct2/show/NCT05032911

Sep 10th, 2021 - This is a descriptive, observational, longitudinal, prospective study consecutively enrolling patients with non-specific neck pain and age-matched asymptomatic participants. The investigators will register sensorimotor control variables, including active range of motion, movement speed, acceleration, smoothness of motion, head repositioning accuracy and motion coupling patterns. These variables...

Acupuncture Combined With Yanqing Zhitong Ointment Acupoint Application in Chronic Non-specific Low Back Pain
https://clinicaltrials.gov/ct2/show/NCT05040243

Sep 10th, 2021 - Carry out a randomized controlled double-blind study, the acupuncture combined with placebo application group was compared with the acupuncture combined with Yanqing Zhitong ointment acupoint application group, 86 patients with chronic non-specific low back pain were included.

The ECEALT Chronic Low Back Pain Study
https://clinicaltrials.gov/ct2/show/NCT05040633

Sep 10th, 2021 - Low back pain (LBP) is one of the most common musculoskeletal disorders and the leading cause of years lived with disability worldwide with significant socioeconomic impacts. Around 10-15 % of LBP patients develop chronic symptoms lasting more than 3 months, and this is considered chronic, with the causes often being "non-specific" with no identifiable causes. Despite the availability of medica...

Muscle Energy Technique and Facet Joint Mobilization in Chronic Neck Pain.
https://clinicaltrials.gov/ct2/show/NCT05040477

Sep 10th, 2021 - Neck pain is a common musculoskeletal disorder that leads to significant disability in the general population. In a 6-month period, 54% of adults suffer from neck pain, and 4.6% experience limitations of important activities because of neck problems(1). Neck pain is a major problem around the world and all age ranges population affected from neck pain dysfunction(2). The prevalence of neck pain...

mHealth Behavioral Cancer Pain Intervention for Medically Undeserved Patients
https://clinicaltrials.gov/ct2/show/NCT04175639

Sep 10th, 2021 - Guided by extensive prior work, the investigators have designed an innovative mHealth behavioral pain coping skills training (PCST) intervention to reduce pain and disability in cancer patients in medically underserved areas (mPCST-Community). Our prior work has tested PCST protocols through in-person sessions at major medical centers where resources and literacy levels are relatively high. mPC...

Effects of Cervical Proprioceptive Training in CMNP
https://clinicaltrials.gov/ct2/show/NCT04941495

Sep 10th, 2021 - Neck pain is a very common complaint. In the general population and musculoskeletal practice, it occurs second to low back pain in its frequency. Neck pain has a point prevalence of nearly 13% and lifetime prevalence of nearly 50%. Neck pain and disability are prevalent throughout the industrialized society. It is a common reason for visits in accidents and emergency departments. In Chiropracti...

"The Efficiency of Laparoscopic-assisted Transversus Abdominis Plane Block for Post-laparoscopic Cholecystectomy Pain
https://clinicaltrials.gov/ct2/show/NCT04641403

Sep 10th, 2021 - This prospective, randomized, controlled, observer and patient-blind study will be conducted by the General Surgery, Anesthesiology and Reanimation Departments of Private Medicabil Hospital in accordance with the Declaration of Helsinki and Good Clinical Practice Guidelines. Hospital ethics committee approval was obtained for the study and the study was conducted between january 2021 and april ...

Oxidative Stress and Surgical Recovery
https://clinicaltrials.gov/ct2/show/NCT04732000

Sep 10th, 2021 - This is a randomized, double-blind, placebo controlled interventional pilot study in 20 patients undergoing first-time total hip arthroplasty (THA) for chronic osteoarthritis at Stanford Medicine. The researchers will screen, enroll and collect biologic and behavioral data from 20 participants as outlined in previous observational and interventional clinical studies undertaken in close collabor...