Jun 9th, 2021 - To develop updated guidelines for the pharmacologic management of rheumatoid arthritis. We developed clinically relevant population, intervention, comparator, and outcomes (PICO) questions. After conducting a systematic literature review, the Grading of Recommendations Assessment, Development and Evaluation (GRADE) approach was used to rate the certainty of evidence. A voting panel comprising c...

Aug 23rd, 2019 - To update evidence-based recommendations for the treatment of patients with ankylosing spondylitis (AS) and nonradiographic axial spondyloarthritis (SpA). We conducted updated systematic literature reviews for 20 clinical questions on pharmacologic treatment addressed in the 2015 guidelines, and for 26 new questions on pharmacologic treatment, treat-to-target strategy, and use of imaging. New q...

Mar 17th, 2023 - Mise à jour technique No433 : Cybersanté et incontinence urinaire chez la femme.|2023|Dufour S,Clancy A,Wu M,|

Mar 16th, 2023 - The clinical application of polygenic risk scores: A points to consider statement of the American College of Medical Genetics and Genomics (ACMG).|2023|Abu-El-Haija A,Reddi HV,Wand H,Rose NC,Mori M,|

Mar 16th, 2023 - Respiratory failure is a significant concern in neuromuscular diseases (NMD). This CHEST guideline examines the literature on the respiratory management of patients with NMD to provide evidence-based recommendations. An expert panel conducted a systematic review addressing the respiratory management of NMD and applied the GRADE approach for assessing the certainty of the evidence and formulatin...

Mar 6th, 2023 - Oncogene-addicted metastatic non-small-cell lung cancer: ESMO Clinical Practice Guideline for diagnosis, treatment and follow-up.|2023|Hendriks LE,Kerr KM,Menis J,Mok TS,Nestle U,|

Mar 1st, 2023 - With a growing number of patients undergoing total knee replacements globally, coupled with an elderly population, the incidence of periprosthetic fractures around total knee replacements is increasing. As such, this is a highly topical subject that is gaining increasing interest within the orthopaedic community. This review provides a narrative synthesis of the most contemporary literature reg...

Feb 27th, 2023 - Cancer survivorship is particularly significant for patients with urologic malignancies, who account for >25% of cancer survivors. The American Cancer Society has a guideline on survivorship care in prostate cancer and the American Urological Association has published a core curriculum on cancer survivorship in urologic cancers. However, there is a lack of high-quality evidence on survivorship ...

Feb 27th, 2023 - Use of Classes of Antihyperglycemic Agents in People With Type 2 Diabetes Based on Level of Estimated Glomerular Filtration Rate.|2023| ,Gilbert J,McFarlane P,Kim J,Jin S,|

Feb 24th, 2023 - Biomarkers are used frequently for noninvasive monitoring and treatment decision making in the management of patients with ulcerative colitis (UC). This American Gastroenterological Association (AGA) guideline is intended to support practitioners in decisions about the use of biomarkers for the management of UC. A multidisciplinary panel of content experts and guideline methodologists used the ...

Feb 23rd, 2023 - The International Society for Heart and Lung Transplantation/Heart Failure Society of America Guideline on Acute Mechanical Circulatory Support.|2023|Bernhardt AM,Copeland H,Deswal A,Gluck J,Givertz MM,|

Feb 18th, 2023 - Points to consider in the practice of postmortem genetic testing: A statement of the American College of Medical Genetics and Genomics (ACMG).|2023|Deignan JL,De Castro M,Horner VL,Johnston T,Macaya D,|

Feb 17th, 2023 - Oral anticoagulation therapy has evolved beyond vitamin K antagonists to include oral direct thrombin inhibitors and factor Xa inhibitors. Collectively known as "direct oral anticoagulants," this class of medications represents the current standard of care for the prevention and treatment of common thrombotic disorders, including atrial fibrillation and venous thromboembolism. Medications that ...

Feb 15th, 2023 - Genital herpes is a common sexually transmitted infection caused by 2 related viruses, herpes simplex type 1 (HSV-1) and herpes simplex type 2 (HSV-2). Infection is lifelong; currently, there is no cure for HSV infection. Antiviral medications may provide clinical benefits to symptomatic persons. Transmission of HSV from a pregnant person to their infant can occur, most commonly during delivery...

Feb 10th, 2023 - Fibrinolysis is a series of enzymatic reactions that degrade insoluble fibrin. Plasminogen activators convert the zymogen plasminogen to the active serine protease plasmin, which cleaves and solubilizes crosslinked fibrin clots into fibrin degradation products. The quantity and quality of fibrinolytic enzymes, their respective inhibitors, and clot structure determine overall fibrinolysis. The q...

Feb 10th, 2023 - Ultrasound Examinations Performed by Registered Nurses in Obstetric, Gynecologic, and Reproductive Medicine Settings: Clinical Competencies and Education Guide, Fifth Edition.|2023| ,|

Feb 10th, 2023 - Falls Prevention, Home Safety, and Rehabilitation Services for People With Parkinson Disease: A Client and Caregiver Guide.|2023|Heyn PC,Wong DC,Hirsch MA,van Wegen EEH,Hein A,|

Feb 10th, 2023 - Ultrasound Examinations Performed by Registered Nurses in Obstetric, Gynecologic, and Reproductive Medicine Settings: Clinical Competencies and Education Guide, Fifth Edition.|2023| ,|

Feb 9th, 2023 - The International Society for Heart and Lung Transplantation/Heart Failure Society of America Guideline on Acute Mechanical Circulatory Support.|2023|Bernhardt AM,Copeland H,Deswal A,Gluck J,Givertz MM,|

Feb 6th, 2023 - The present guideline is an update and extension of the ESPEN scientific guideline on Clinical Nutrition in Inflammatory Bowel Disease published first in 2017. The guideline has been rearranged according to the ESPEN practical guideline on Clinical Nutrition in Inflammatory Bowel Disease published in 2020. All recommendations have been checked and, if needed, revised based on new literature, be...