Jan 23rd, 2017 - Prior to the availability of clotting factor concentrates, the natural history of arthropathy in severe haemophilia was well described, with recurrent bleeds into joints leading to progressive joint damage and ultimate destruction with associated functional problems. The prophylactic use of factor concentrates has dramatically modified the natural history of haemophilic arthropathy. The e...
William M. Lee
Feb 29th, 2012 - Acute liver failure (ALF) is a rare condition in which rapid deterioration of liver function results in altered mentation and coagulopathy in individuals without known pre-existing liver disease. U.
May 11th, 2019 - Cardiac rehabilitation (CR) is an evidence-based intervention that uses patient education, health behavior modification, and exercise training to improve secondary prevention outcomes in patients with cardiovascular disease. CR programs reduce morbidity and mortality rates in adults with ischemic heart disease, heart failure, or cardiac surgery but are significantly underused, with only a minor...
Journal of the American Academy of Dermatology; Sidbury R, Davis DM et. al.
May 12th, 2014 - Atopic dermatitis is a chronic, pruritic inflammatory dermatosis that affects up to 25% of children and 2% to 3% of adults. This guideline addresses important clinical questions that arise in atopic dermatitis management and care, providing recommendations based on the available evidence. In this third of 4 sections, treatment of atopic dermatitis with phototherapy and systemic immunomodulators...
Gastrointestinal Endoscopy; Laine L, Kaltenbach T et. al.
Feb 24th, 2015 - SCENIC international consensus statement on surveillance and management of dysplasia in inflammatory bowel disease.|2015|Laine L,Kaltenbach T,Barkun A,McQuaid KR,Subramanian V,|methods,etiology,pathology,surgery,complications,methods,
Clinical Infectious Diseases : an Official Publication Of... Lewinsohn DM, Leonard MK et. al.
Dec 9th, 2016 - Individuals infected with Mycobacterium tuberculosis (Mtb) may develop symptoms and signs of disease (tuberculosis disease) or may have no clinical evidence of disease (latent tuberculosis infection [LTBI]). Tuberculosis disease is a leading cause of infectious disease morbidity and mortality worldwide, yet many questions related to its diagnosis remain. A task force supported by the American T...
International Journal of Gynecological Cancer : Official ... Oonk MHM, Planchamp F et. al.
Apr 25th, 2017 - The aim of this study was to develop clinically relevant and evidence-based guidelines as part of European Society of Gynaecological Oncology's mission to improve the quality of care for women with gynecologic cancers across Europe. The European Society of Gynaecological Oncology Council nominated an international development group made of practicing clinicians who provide care to patients with...
Endoscopy Dumonceau JM, Deprez PH et. al.
May 16th, 2017 - For pancreatic solid lesions, ESGE recommends performing endoscopic ultrasound (EUS)-guided sampling as first-line procedure when a pathological diagnosis is required. Alternatively, percutaneous sampling may be considered in metastatic disease.Strong recommendation, moderate quality evidence.In the case of negative or inconclusive results and a high degree of suspicion of malignant disease, ES...
JAMA Greer DM, Shemie SD et. al.
Aug 7th, 2020 - There are inconsistencies in concept, criteria, practice, and documentation of brain death/death by neurologic criteria (BD/DNC) both internationally and within countries. To formulate a consensus statement of recommendations on determination of BD/DNC based on review of the literature and expert opinion of a large multidisciplinary, international panel. Relevant international professional soci...
The Journal of Clinical Endocrinology and Metabolism; Bhasin S, Brito JP et. al.
Mar 21st, 2018 - To update the "Testosterone Therapy in Men With Androgen Deficiency Syndromes" guideline published in 2010. The participants include an Endocrine Society-appointed task force of 10 medical content experts and a clinical practice guideline methodologist. This evidence-based guideline was developed using the Grading of Recommendations, Assessment, Development, and Evaluation approach to describe ...
Gut Everett SM, Griffiths H et. al.
Jun 21st, 2016 - Much has changed since the last guideline of 2008, both in endoscopy and in the practice of obtaining informed consent, and it is vital that all endoscopists who are responsible for performing invasive and increasingly risky procedures are aware of the requirements for obtaining valid consent. This guideline is restricted to GI endoscopy but we cover elective and acute or emergency procedures. ...
Endoscopy Domagk D, Oppong KW et. al.
Oct 19th, 2018 - The European Society of Gastrointestinal Endoscopy and United European Gastroenterology present a short list of key performance measures for endoscopic ultrasound (EUS) and endoscopic retrograde cholangiopancreatography (ERCP). We recommend that endoscopy services across Europe adopt the following seven key and one minor performance measures for EUS and ERCP, for measurement and evaluation in d...
Annals of Internal Medicine; Navaneethan SD, Zoungas S et. al.
Nov 9th, 2020 - The Kidney Disease: Improving Global Outcomes (KDIGO) organization developed a clinical practice guideline in 2020 for the management of patients with diabetes and chronic kidney disease (CKD). The KDIGO Work Group (WG) was tasked with developing the guideline for diabetes management in CKD. It defined the scope of the guideline, gathered evidence, determined systematic review topics, and grade...
American Journal of Respiratory and Critical Care Medicine; Vogelmeier CF, Criner GJ et. al.
Jan 27th, 2017 - This Executive Summary of the Global Strategy for the Diagnosis, Management, and Prevention of COPD, Global Initiative for Chronic Obstructive Lung Disease (GOLD) 2017 report focuses primarily on the revised and novel parts of the document. The most significant changes include: (1) the assessment of chronic obstructive pulmonary disease has been refined to separate the spirometric assessment fr...
Endoscopy Hassan C, East J et. al.
Jul 11th, 2019 - ESGE recommends a low fiber diet on the day preceding colonoscopy.Strong recommendation, moderate quality evidence.ESGE recommends the use of enhanced instructions for bowel preparation.Strong recommendation, moderate quality evidence.ESGE suggests adding oral simethicone to bowel preparation.Weak recommendation, moderate quality evidence.ESGE recommends split-dose bowel preparation for electiv...
Blood Advances; Neunert C, Terrell DR et. al.
Dec 3rd, 2019 - Despite an increase in the number of therapies available to treat patients with immune thrombocytopenia (ITP), there are minimal data from randomized trials to assist physicians with the management of patients. These evidence-based guidelines of the American Society of Hematology (ASH) are intended to support patients, clinicians, and other health care professionals in their decisions about the...
Gut Oakland K, Chadwick G et. al.
Feb 22nd, 2019 - This is the first UK national guideline to concentrate on acute lower gastrointestinal bleeding (LGIB) and has been commissioned by the Clinical Services and Standards Committee of the British Society of Gastroenterology (BSG). The Guidelines Development Group consisted of representatives from the BSG Endoscopy Committee, the Association of Coloproctology of Great Britain and Ireland, the Briti...
BMJ (Clinical Research Ed.); Lamontagne F, Rochwerg B et. al.
Aug 11th, 2018 - Corticosteroid therapy for sepsis: a clinical practice guideline.|2018|Lamontagne F,Rochwerg B,Lytvyn L,Guyatt GH,Møller MH,|therapeutic use,drug therapy,
Clinical Infectious Diseases : an Official Publication Of... McDonald LC, Gerding DN et. al.
Feb 20th, 2018 - A panel of experts was convened by the Infectious Diseases Society of America (IDSA) and Society for Healthcare Epidemiology of America (SHEA) to update the 2010 clinical practice guideline on Clostridium difficile infection (CDI) in adults. The update, which has incorporated recommendations for children (following the adult recommendations for epidemiology, diagnosis, and treatment), includes ...
Blood La Rosée P, Horne A et. al.
Apr 17th, 2019 - Hemophagocytic lymphohistiocytosis (HLH) is a severe hyperinflammatory syndrome induced by aberrantly activated macrophages and cytotoxic T cells. The primary (genetic) form, caused by mutations affecting lymphocyte cytotoxicity and immune regulation, is most common in children, whereas the secondary (acquired) form is most frequent in adults. Secondary HLH is commonly triggered by infections o...