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About 2,418 results

Aspirin Use to Prevent Preeclampsia and Related Morbidity and Mortality: US Preventive ...
https://doi.org/10.1001/jama.2021.14781
JAMA , Davidson KW et. al.

Sep 29th, 2021 - Preeclampsia is one of the most serious health problems that affect pregnant persons. It is a complication in approximately 4% of pregnancies in the US and contributes to both maternal and infant morbidity and mortality. Preeclampsia also accounts for 6% of preterm births and 19% of medically indicated preterm births in the US. There are racial and ethnic disparities in the prevalence of and mo...

Medical cannabis or cannabinoids for chronic pain: a clinical practice guideline.
https://doi.org/10.1136/bmj.n2040
BMJ (Clinical Research Ed.); Busse JW, Vankrunkelsven P et. al.

Sep 10th, 2021 - What is the role of medical cannabis or cannabinoids for people living with chronic pain due to cancer or non-cancer causes? Chronic pain is common and distressing and associated with considerable socioeconomic burden globally. Medical cannabis is increasingly used to manage chronic pain, particularly in jurisdictions that have enacted policies to reduce use of opioids; however, existing guidel...

Recommendations for Prevention and Control of Influenza in Children, 2021-2022.
https://doi.org/10.1542/peds.2021-053745
Pediatrics

Sep 9th, 2021 - This technical report accompanies the recommendations of the American Academy of Pediatrics for the routine use of the influenza vaccine and antiviral medications in the prevention and treatment of influenza in children during the 2021-2022 season. Influenza vaccination is an important intervention to protect vulnerable populations and reduce the burden of respiratory illnesses during circulati...

Update to U.S. Selected Practice Recommendations for Contraceptive Use: Self-Administra...
https://doi.org/10.15585/mmwr.mm7020a2
MMWR. Morbidity and Mortality Weekly Report; Curtis KM, Nguyen A et. al.

May 21st, 2021 - U.S. Selected Practice Recommendations for Contraceptive Use (U.S. SPR), adapted by CDC from global guidance developed by the World Health Organization (WHO), provides evidence-based guidance on contraceptive use for U.S. health care providers (1). During January-February, 2021, CDC evaluated the 2019 WHO recommendation on self-administered subcutaneous depot medroxyprogesterone acetate (DMPA-S...

Guidelines for clinical evaluation of anti-cancer drugs.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8253284
Cancer Science; Minami H, Kiyota N et. al.

May 16th, 2021 - Clinical studies intended for regulatory approval must demonstrate the clinical benefits of the drug in a target population. Clinical development of a drug proceeds by stepwise clinical studies; after safety and pharmacokinetics are evaluated and the recommended dosage and administration are determined, efficacy and safety are evaluated in an exploratory manner, and finally clinical benefits ar...

Surgery and opioids: evidence-based expert consensus guidelines on the perioperative us...
https://doi.org/10.1016/j.bja.2021.02.030
British Journal of Anaesthesia; Srivastava D, Hill S et. al.

Apr 19th, 2021 - There are significant concerns regarding prescription and misuse of prescription opioids in the perioperative period. The Faculty of Pain Medicine at the Royal College of Anaesthetists have produced this evidence-based expert consensus guideline on surgery and opioids along with the Royal College of Surgery, Royal College of Psychiatry, Royal College of Nursing, and the British Pain Society. Th...

Appropriate Use of Short-Course Antibiotics in Common Infections: Best Practice Advice ...
https://doi.org/10.7326/M20-7355
Annals of Internal Medicine; Lee RA, Centor RM et. al.

Apr 6th, 2021 - Antimicrobial overuse is a major health care issue that contributes to antibiotic resistance. Such overuse includes unnecessarily long durations of antibiotic therapy in patients with common bacterial infections, such as acute bronchitis with chronic obstructive pulmonary disease (COPD) exacerbation, community-acquired pneumonia (CAP), urinary tract infections (UTIs), and cellulitis. This artic...

SEOM clinical guidelines for anaemia treatment in cancer patients (2020).
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8057996
Clinical & Translational Oncology : Official Publication ... Escobar Álvarez Y, de Las Peñas Bataller R et. al.

Mar 27th, 2021 - Anaemia is defined by the presence of haemoglobin (Hb) levels < 13 g/dL in men and 12 g/dL in women. Up to 39% of cancer patients present it at the time of diagnosis and up to 40% have iron deficiency. Anaemia causes fatigue, functional deterioration and a reduction in the quality of life; it has also been associated with a poorer response to anti-tumour treatment and lower survival. Basic diag...

The Use of Contrast Agents in Interventional Pain Procedures: A Multispecialty and Mult...
https://doi.org/10.1213/ANE.0000000000005443 10.1001/jama.2019.9751
Anesthesia and Analgesia; Benzon HT, Maus TP et. al.

Mar 24th, 2021 - This Practice Advisory presents a comprehensive and evidence-based set of position statements and recommendations for the use of contrast media in interventional pain procedures. The advisory was established by an international panel of experts under the auspices of 11 multinational and multispecialty organizations based on a comprehensive review of the literature up to December 31, 2019. The a...

Glucocorticoid use in patients with adrenal insufficiency following administration of t...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7872824
Pituitary Katznelson L, Gadelha M

Feb 11th, 2021 - Side effects of the coronavirus disease 2019 (COVID-19) vaccines include pain at the injection site, fatigue, headache, myalgias, arthralgias, chills, and fever, all of which can be early indicators of an increased need for glucocorticoid replacement in patients with adrenal insufficiency. The Pituitary Society surveyed its membership to understand planned approaches to glucocorticoid managemen...

American College of Rheumatology, American Academy of Dermatology, Rheumatologic Dermat...
https://doi.org/10.1002/art.41683
Arthritis & Rheumatology (Hoboken, N.J.); Rosenbaum JT, Costenbader KH et. al.

Feb 10th, 2021 - Four major medical societies involved with hydroxychloroquine (HCQ) therapy concur on the need for common principles and cooperation to minimize the risk of ocular toxicity. At a daily dosage of ≤5 mg/kg/day actual body weight, the risk of retinal toxicity from HCQ is <2% for usage up to 10 years. Widespread adoption of more sensitive testing techniques, such as optical coherence tomography and...

Directive clinique no 414 : Prise en charge des grossesses de localisation indéterminée...
https://doi.org/10.1016/j.jogc.2021.01.001
Journal of Obstetrics and Gynaecology Canada : JOGC = Jou... Po L, Thomas J et. al.

Jan 17th, 2021 - Fournir un algorithme fondé sur des données probantes pour orienter le diagnostic et la prise en charge de la grossesse de localisation indéterminée et de la grossesse ectopique tubaire ou non tubaire. Toutes les patientes en âge de procréer. BéNéFICES, RISQUES ET COûTS: La mise en œuvre de la présente directive a pour objectif de bénéficier aux patientes ayant obtenu un résultat positif pour l...

Guideline No. 414: Management of Pregnancy of Unknown Location and Tubal and Nontubal E...
https://doi.org/10.1016/j.jogc.2021.01.002
Journal of Obstetrics and Gynaecology Canada : JOGC = Jou... Po L, Thomas J et. al.

Jan 17th, 2021 - To provide an evidence-based algorithm to guide the diagnosis and management of pregnancy of unknown location and tubal and nontubal ectopic pregnancy. All patients of reproductive age. The implementation of this guideline aims to benefit patients with positive β-human chorionic gonadotropin results and provide physicians with a standard algorithm for expectant, medical, and surgical treatment ...

Chest CT Diagnosis and Clinical Management of Drug-Related Pneumonitis in Patients Rece...
https://doi.org/10.1016/j.chest.2020.11.027
Chest Johkoh T, Lee KS et. al.

Jan 16th, 2021 - Use of molecular targeting agents and immune checkpoint inhibitors (ICIs) has increased the frequency and broadened the spectrum of lung toxicity, particularly in patients with cancer. The diagnosis of drug-related pneumonitis (DRP) is usually achieved by excluding other potential known causes. Awareness of the incidence and risk factors for DRP is becoming increasingly important. The severity ...

Meningococcal Vaccination: Recommendations of the Advisory Committee on Immunization Pr...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7527029
MMWR. Recommendations and Reports : Morbidity and Mortali... Mbaeyi SA, Bozio CH et. al.

Jan 9th, 2021 - This report compiles and summarizes all recommendations from CDC's Advisory Committee on Immunization Practices (ACIP) for use of meningococcal vaccines in the United States. As a comprehensive summary and update of previously published recommendations, it replaces all previously published reports and policy notes. This report also contains new recommendations for administration of booster dose...

Use of Ebola Vaccine: Recommendations of the Advisory Committee on Immunization Practic...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7802368
MMWR. Recommendations and Reports : Morbidity and Mortali... Choi MJ, Cossaboom CM et. al.

Jan 9th, 2021 - This report summarizes the recommendations of the Advisory Committee on Immunization Practices (ACIP) for use of the rVSVΔG-ZEBOV-GP Ebola vaccine (Ervebo) in the United States. The vaccine contains rice-derived recombinant human serum albumin and live attenuated recombinant vesicular stomatitis virus (VSV) in which the gene encoding the glycoprotein of VSV was replaced with the gene encoding t...

Options for Prevention and Management of Menstrual Bleeding in Adolescent Patients Unde...
https://doi.org/10.1097/AOG.0000000000004209
Obstetrics and Gynecology;

Jan 6th, 2021 - Obstetrician-gynecologists frequently are consulted either before the initiation of cancer treatment to request menstrual suppression or during an episode of severe heavy bleeding to stop bleeding emergently. Adolescents presenting emergently with severe uterine bleeding usually require only medical management; surgical management rarely is required. Surgical management should be considered for...

Breast conservation and axillary management after primary systemic therapy in patients ...
https://doi.org/10.1016/S1470-2045(20)30580-5
The Lancet. Oncology; Dubsky P, Pinker K et. al.

Jan 3rd, 2021 - Primary systemic therapy is increasingly used in the treatment of patients with early-stage breast cancer, but few guidelines specifically address optimal locoregional therapies. Therefore, we established an international consortium to discuss clinical evidence and to provide expert advice on technical management of patients with early-stage breast cancer. The steering committee prepared six wo...

American College of Rheumatology Guidance for the Management of Rheumatic Disease in Ad...
https://doi.org/10.1002/art.41596
Arthritis & Rheumatology (Hoboken, N.J.); Mikuls TR, Johnson SR et. al.

Dec 6th, 2020 - To provide guidance to rheumatology providers on the management of adult rheumatic disease in the context of the coronavirus disease 2019 (COVID-19) pandemic. A task force, including 10 rheumatologists and 4 infectious disease specialists from North America, was convened. Clinical questions were collated, and an evidence report was rapidly generated and disseminated. Questions and drafted state...

Managing Asthma in Adolescents and Adults: 2020 Asthma Guideline Update From the Nation...
https://doi.org/10.1001/jama.2020.21974
JAMA Cloutier MM, Dixon AE et. al.

Dec 4th, 2020 - Asthma is a major public health problem worldwide and is associated with excess morbidity, mortality, and economic costs associated with lost productivity. The National Asthma Education and Prevention Program has released the 2020 Asthma Guideline Update with updated evidence-based recommendations for treatment of patients with asthma. To report updated recommendations for 6 topics for clinical...