×
About 2,475 results

Plasma exchange and glucocorticoid dosing for patients with ANCA-associated vasculitis:...
https://doi.org/10.1136/bmj-2021-064597
BMJ (Clinical Research Ed.); Zeng L, Walsh M et. al.

Feb 27th, 2022 - What is the role of plasma exchange and what is the optimal dose of glucocorticoids in the first 6 months of therapy of patients with antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV)? This guideline was triggered by the publication of a new randomised controlled trial. Existing guideline recommendations vary regarding the use of plasma exchange in AAV and lack explicit rec...

AGA Clinical Practice Guideline on Systemic Therapy for Hepatocellular Carcinoma.
https://doi.org/10.1053/j.gastro.2021.12.276
Gastroenterology Su GL, Altayar O et. al.

Feb 26th, 2022 - Hepatocellular carcinoma (HCC), the most common primary liver cancer, remains a deadly cancer, with an incidence that has tripled in the United States since 1980. In recent years, new systemic therapies for HCC have been approved and a critical assessment of the existing data is necessary to balance benefits and harms and inform the development of evidence-based guidelines. The American Gastroe...

Interim Guidance: 4-Month Rifapentine-Moxifloxacin Regimen for the Treatment of Drug-Su...
https://doi.org/10.15585/mmwr.mm7108a1
MMWR. Morbidity and Mortality Weekly Report; Carr W, Kurbatova E et. al.

Feb 25th, 2022 - On May 5, 2021, CDC's Tuberculosis Trials Consortium and the National Institutes of Health (NIH)-sponsored AIDS Clinical Trials Group (ACTG) published results from a randomized controlled trial indicating that a 4-month regimen containing rifapentine (RPT), moxifloxacin (MOX), isoniazid (INH), and pyrazinamide (PZA) was as effective as the standard 6-month regimen for tuberculosis (TB) treatmen...

Intravenous contrast medium extravasation: systematic review and updated ESUR Contrast ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9038843
European Radiology; Roditi G, Khan N et. al.

Feb 18th, 2022 - Guidelines for management and prevention of contrast media extravasation have not been updated recently. In view of emerging research and changing working practices, this review aims to inform update on the current guidelines. In this paper, we review the literature pertaining to the pathophysiology, diagnosis, risk factors and treatments of contrast media extravasation. A suggested protocol an...

Prevention of herpes zoster: recommendations of the Advisory Committee on Immunization ...
https://www.ncbi.nlm.nih.gov/pubmed/18528318
MMWR. Recommendations and Reports : Morbidity and Mortali... Harpaz R, Ortega-Sanchez IR et. al.

Jun 6th, 2008 - These recommendations represent the first statement by the Advisory Committee on Immunization Practices (ACIP) on the use of a live attenuated vaccine for the prevention of herpes zoster (zoster) (i.e., shingles) and its sequelae, which was licensed by the U.S. Food and Drug Administration (FDA) on May 25, 2006. This report summarizes the epidemiology of zoster and its sequelae, describes the z...

Screening and Interventions to Prevent Dental Caries in Children Younger Than 5 Years: ...
https://doi.org/10.1001/jama.2021.20007
JAMA , Davidson KW et. al.

Dec 8th, 2021 - Dental caries is the most common chronic disease in children in the US. According to the 2011-2016 National Health and Nutrition Examination Survey, approximately 23% of children aged 2 to 5 years had dental caries in their primary teeth. Prevalence is higher in Mexican American children (33%) and non-Hispanic Black children (28%) than in non-Hispanic White children (18%). Dental caries in earl...

Hypertension Pharmacological Treatment in Adults: A World Health Organization Guideline...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8654104
Hypertension (Dallas, Tex. : 1979); Al-Makki A, DiPette D et. al.

Nov 16th, 2021 - Hypertension is a major cause of cardiovascular disease and deaths worldwide especially in low- and middle-income countries. Despite the availability of safe, well-tolerated, and cost-effective blood pressure (BP)-lowering therapies, <14% of adults with hypertension have BP controlled to a systolic/diastolic BP <140/90 mm Hg. We report new hypertension treatment guidelines, developed in accorda...

2021 Focused Update Consensus Guidelines of the Asia Pacific Heart Rhythm Society on St...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8763451
Thrombosis and Haemostasis; Chao TF, Joung B et. al.

Nov 14th, 2021 - The consensus of the Asia Pacific Heart Rhythm Society (APHRS) on stroke prevention in atrial fibrillation (AF) has been published in 2017 which provided useful clinical guidance for cardiologists, neurologists, geriatricians, and general practitioners in the Asia-Pacific region. In these years, many important new data regarding stroke prevention in AF were reported. The practice guidelines sub...

Aspirin Use to Prevent Preeclampsia and Related Morbidity and Mortality: US Preventive ...
https://doi.org/10.1001/jama.2021.14781
JAMA , Davidson KW et. al.

Sep 29th, 2021 - Preeclampsia is one of the most serious health problems that affect pregnant persons. It is a complication in approximately 4% of pregnancies in the US and contributes to both maternal and infant morbidity and mortality. Preeclampsia also accounts for 6% of preterm births and 19% of medically indicated preterm births in the US. There are racial and ethnic disparities in the prevalence of and mo...

Clinical practice guidelines standardisation of immunosuppressive and anti-infective dr...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8447621
BMC Nephrology; Dudley J, Christian M et. al.

Sep 18th, 2021 - Clinical practice guidelines standardisation of immunosuppressive and anti-infective drug regimens in UK paediatric renal transplantation: the harmonisation programme.|2021|Dudley J,Christian M,Andrews A,Andrews N,Baker J,|administration & dosage,administration & dosage,administration & dosage,

Medical cannabis or cannabinoids for chronic pain: a clinical practice guideline.
https://doi.org/10.1136/bmj.n2040
BMJ (Clinical Research Ed.); Busse JW, Vankrunkelsven P et. al.

Sep 10th, 2021 - What is the role of medical cannabis or cannabinoids for people living with chronic pain due to cancer or non-cancer causes? Chronic pain is common and distressing and associated with considerable socioeconomic burden globally. Medical cannabis is increasingly used to manage chronic pain, particularly in jurisdictions that have enacted policies to reduce use of opioids; however, existing guidel...

Recommendations for Prevention and Control of Influenza in Children, 2021-2022.
https://doi.org/10.1542/peds.2021-053745
Pediatrics

Sep 9th, 2021 - This technical report accompanies the recommendations of the American Academy of Pediatrics for the routine use of the influenza vaccine and antiviral medications in the prevention and treatment of influenza in children during the 2021-2022 season. Influenza vaccination is an important intervention to protect vulnerable populations and reduce the burden of respiratory illnesses during circulati...

Acute Ischemic Priapism: An AUA/SMSNA Guideline.
https://doi.org/10.1097/JU.0000000000002236
The Journal of Urology; Bivalacqua TJ, Allen BK et. al.

Sep 9th, 2021 - Priapism is a persistent penile erection that continues hours beyond, or is unrelated to, sexual stimulation and results in a prolonged and uncontrolled erection. Given its time-dependent and progressive nature, priapism is a situation that both urologists and emergency medicine practitioners must be familiar with and comfortable managing. Acute ischemic priapism, characterized by little or no ...

EULAR points to consider for the management of difficult-to-treat rheumatoid arthritis.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8761998
Annals of the Rheumatic Diseases; Nagy G, Roodenrijs NMT et. al.

Aug 20th, 2021 - To develop evidence-based European Alliance of Associations for Rheumatology (EULAR) points to consider (PtCs) for the management of difficult-to-treat rheumatoid arthritis (D2T RA). An EULAR Task Force was established comprising 34 individuals: 26 rheumatologists, patient partners and rheumatology experienced health professionals. Two systematic literature reviews addressed clinical questions ...

Antithrombotic Therapy for VTE Disease: Second Update of the CHEST Guideline and Expert...
https://doi.org/10.1016/j.chest.2021.07.055
Chest Stevens SM, Woller SC et. al.

Aug 6th, 2021 - This is the 2nd update to the 9th edition of these guidelines. We provide recommendations on 17 PICO (Population, Intervention, Comparator, Outcome) questions, four of which have not been addressed previously. We generate strong and weak recommendations based on high-, moderate-, and low-certainty evidence, using GRADE (Grading of Recommendations, Assessment, Development, and Evaluation) method...

Canadian Association of Gastroenterology Clinical Practice Guideline for Immunizations ...
https://doi.org/10.1053/j.gastro.2021.04.034
Gastroenterology Jones JL, Tse F et. al.

Aug 3rd, 2021 - The effectiveness and safety of vaccinations can be altered by immunosuppressive therapies, and perhaps by inflammatory bowel disease (IBD) itself. These recommendations developed by the Canadian Association of Gastroenterology and endorsed by the American Gastroenterological Association, aim to provide guidance on immunizations in adult and pediatric patients with IBD. This publication focused...

EULAR recommendations for intra-articular therapies.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8458067
Annals of the Rheumatic Diseases; Uson J, Rodriguez-García SC et. al.

May 27th, 2021 - To establish evidence-based recommendations to guide health professionals using intra-articular therapies (IAT) in adult patients with peripheral arthropathies. A multidisciplinary international task force established the objectives, users and scope and the need for background information, including systematic literature reviews) and two surveys addressed to healthcare providers and patients th...

Update to U.S. Selected Practice Recommendations for Contraceptive Use: Self-Administra...
https://doi.org/10.15585/mmwr.mm7020a2
MMWR. Morbidity and Mortality Weekly Report; Curtis KM, Nguyen A et. al.

May 21st, 2021 - U.S. Selected Practice Recommendations for Contraceptive Use (U.S. SPR), adapted by CDC from global guidance developed by the World Health Organization (WHO), provides evidence-based guidance on contraceptive use for U.S. health care providers (1). During January-February, 2021, CDC evaluated the 2019 WHO recommendation on self-administered subcutaneous depot medroxyprogesterone acetate (DMPA-S...

Guidelines for clinical evaluation of anti-cancer drugs.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8253284
Cancer Science; Minami H, Kiyota N et. al.

May 16th, 2021 - Clinical studies intended for regulatory approval must demonstrate the clinical benefits of the drug in a target population. Clinical development of a drug proceeds by stepwise clinical studies; after safety and pharmacokinetics are evaluated and the recommended dosage and administration are determined, efficacy and safety are evaluated in an exploratory manner, and finally clinical benefits ar...

Appropriate Systemic Therapy Dosing for Obese Adult Patients With Cancer: ASCO Guidelin...
https://doi.org/10.1200/JCO.21.00471
Journal of Clinical Oncology : Official Journal of the Am... Griggs JJ, Bohlke K et. al.

May 4th, 2021 - To provide recommendations for appropriate dosing of systemic antineoplastic agents in obese adults with cancer. A systematic review of the literature collected evidence regarding dosing of chemotherapy, immunotherapy, and targeted therapies in obese adults with cancer. PubMed and the Cochrane Library were searched for randomized controlled trials, meta-analyses, or cohort studies published fro...