Food and Drug Administration
Dec 8th, 2008 - The guideline is to be used as an aid in designing and conducting studies to establish drug stability in support of original, abbreviated or supplements to new animal drug applications (NADAs/ANADAs). The guideline will provide a framework within which stability studies can be conducted to provide meaningful and sufficient data.
United States Pharmacopeia (USP)
Apr 30th, 2016 - Parenteral drug products include both injections and implanted drug products that are injected through the skin or other external boudary tissue, or implanted within the body to allow the direct administration of the active drug substance(s) into blood vessels, organs, tissues, or lesions. Injections may exist as either imeediate- or extended-release dosage forms that provide continuous release.
Phyllis W. Speiser
Aug 31st, 2010 - We recommend universal newborn screening for severe steroid 21-hydroxylase deficiency followed by confirmatory tests. We recommend that prenatal treatment of CAH continue to be regarded as experimental.
Eric S. Schwenk
Jun 30th, 2018 - Evidence supports the use of ketamine for acute pain in a variety of contexts, including as a stand-alone treatment, as an adjunct to opioids, and, to a lesser extent, as an intranasal formulation. Contraindications for acute pain are similar to those for chronic pain, partly based on the observation that the dosage ranges are similar.
Nov 21st, 2017 - These guidelines provide a recommendation on iodine thyroid blocking (ITB), via oral administration of stable iodine, as an urgent protective action in responding to a nuclear accident. This recommendation aims to support emergency planners, policy makers, public health specialists, clinicians and other relevant stakeholders, in order to strengthen public health preparedness for radiation emerg.
Jan 3rd, 2012 - AED-ARV administration may be indicated in up to 55% of people taking ARVs. Patients receiving phenytoin may require a lopinavir/ritonavir dosage increase of ~50% to maintain unchanged serum concentrations (Level C).
R. Gary Rozier
Nov 30th, 2010 - This article presents evidence-based clinical recommendations for the prescription of dietary fluoride supplements. The recommendations were developed by an expert panel convened by the American Dental Association (ADA) Council on Scientific Affairs (CSA).
Hutchinson, A.,et al
Jul 31st, 2018 - There is limited evidence to support the safety and efficacy of both topical and systemic ?-blockers to promote regression of periocular hemangiomas. Additional research may confirm the best dosage and route of administration to maximize efficacy in reducing induced astigmatism and amblyopia associated with periocular hemangiomas while minimizing side effects.
Dec 9th, 2018 - One in 4 Americans >40 years of age takes a statin to reduce the risk of myocardial infarction, ischemic stroke, and other complications of atherosclerotic disease. The most effective statins produce a mean reduction in low-density lipoprotein cholesterol of 55% to 60% at the maximum dosage, and 6 of the 7 marketed statins are available in generic form, which makes them affordable for most pati.
Sep 29th, 2019 - After increasing every year for more than a decade, annual opioid prescriptions in the United States peaked at 255 million in 2012 and then decreased to 191 million in 2017. i More judicious opioid analgesic prescribing can benefit individual patients as well as public health when opioid analgesic use is limited to situations where benefits of opioids are likely to outweigh risks. At the same ...
Pediatrics Moyer VA,
May 6th, 2014 - Update of the 2004 US Preventive Services Task Force (USPSTF) recommendation on prevention of dental caries in preschool-aged children. The USPSTF reviewed the evidence on prevention of dental caries by primary care clinicians in children 5 years and younger, focusing on screening for caries, assessment of risk for future caries, and the effectiveness of various interventions that have possible...
Jul 29th, 2014 - Palivizumab was licensed in June 1998 by the Food and Drug Administration for the reduction of serious lower respiratory tract infection caused by respiratory syncytial virus (RSV) in children at increased risk of severe disease. Since that time, the American Academy of Pediatrics has updated its guidance for the use of palivizumab 4 times as additional data became available to provide a better...
JAMA Günthard HF, Aberg JA et. al.
Jul 19th, 2014 - New data and antiretroviral regimens expand treatment choices in resource-rich settings and warrant an update of recommendations to treat adults infected with human immunodeficiency virus (HIV). To provide updated treatment recommendations for adults with HIV, emphasizing when to start treatment; what treatment to start; the use of laboratory monitoring tools; and managing treatment failure, sw...
Annals of Internal Medicine; LeFevre ML,
Sep 9th, 2014 - Update of the 1996 U.S. Preventive Services Task Force (USPSTF) recommendation on aspirin prophylaxis in pregnancy. The USPSTF reviewed the evidence on the effectiveness of low-dose aspirin in preventing preeclampsia in women at increased risk and in decreasing adverse maternal and perinatal health outcomes, and assessed the maternal and fetal harms of low-dose aspirin during pregnancy. This re...
MMWR. Recommendations and Reports : Morbidity and Mortali... Liang JL, Tiwari T et. al.
Apr 27th, 2018 - This report compiles and summarizes all recommendations from CDC's Advisory Committee on Immunization Practices (ACIP) regarding prevention and control of tetanus, diphtheria, and pertussis in the United States. As a comprehensive summary of previously published recommendations, this report does not contain any new recommendations and replaces all previously published reports and policy notes; ...
Journal of Clinical Oncology : Official Journal of the Am... Khorana AA, Mangu PB et. al.
Apr 11th, 2017 - Purpose To update the Potentially Curable Pancreatic Cancer: American Society of Clinical Oncology Clinical Practice Guideline published on May 31, 2016. The October 2016 update focuses solely on new evidence that pertains to clinical question 4 of the guideline: What is the appropriate adjuvant regimen for patients with pancreatic cancer who have undergone an R0 or R1 resection of their primar...
MMWR. Morbidity and Mortality Weekly Report; Grohskopf LA, Sokolow LZ et. al.
Jun 7th, 2018 - Intranasally administered live attenuated influenza vaccine (LAIV) was initially licensed in the United States in 2003 as a trivalent formulation (LAIV3) (FluMist, MedImmune, LLC). Quadrivalent live attenuated influenza vaccine (LAIV4) (FluMist Quadrivalent, MedImmune) has been licensed in the United States since 2012 and was first available during the 2013-14 influenza season, replacing LAIV3....
JAMA Dermatology; Crowley JJ, Weinberg JM et. al.
Dec 4th, 2014 - Nail psoriasis can be difficult to treat and has a significant effect on quality of life. Relatively few controlled trials evaluating treatments for nail psoriasis have been published. There is an unmet need for treatment recommendations to guide therapeutic decisions. To develop treatment recommendations for nail psoriasis from the Medical Board of the National Psoriasis Foundation. A PubMed s...
Rheumatology (Oxford, England); Flint J, Panchal S et. al.
Jan 11th, 2016 - BSR and BHPR guideline on prescribing drugs in pregnancy and breastfeeding-Part I: standard and biologic disease modifying anti-rheumatic drugs and corticosteroids.|2016|Flint J,Panchal S,Hurrell A,van de Venne M,Gayed M,|administration & dosage,adverse effects,therapeutic use,administration & dosage,adverse effects,therapeutic use,administration & dosage,adverse effects,therapeutic use,standar...
The American Journal of Psychiatry; Reus VI, Fochtmann LJ et. al.
May 2nd, 2016 - The American Psychiatric Association Practice Guideline on the Use of Antipsychotics to Treat Agitation or Psychosis in Patients With Dementia.|2016|Reus VI,Fochtmann LJ,Eyler AE,Hilty DM,Horvitz-Lennon M,|administration & dosage,adverse effects,complications,physiopathology,psychology,diagnosis,drug therapy,etiology,diagnosis,drug therapy,etiology,