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AGA Clinical Practice Update on Management of Refractory Celiac Disease: Expert Review.
https://doi.org/10.1053/j.gastro.2022.07.086
Gastroenterology Green PHR, Paski S et. al.

Sep 23rd, 2022 - The purpose of this expert review is to summarize the diagnosis and management of refractory celiac disease. It will review evaluation of patients with celiac disease who have persistent or recurrent symptoms, differential diagnosis, nutritional support, potential therapeutic options, and surveillance for complications of this condition. This expert review was commissioned and approved by the A...

AGA Clinical Practice Update: Diagnosis and Management of Nonalcoholic Fatty Liver Dise...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9398982
Gastroenterology Long MT, Noureddin M et. al.

Jul 17th, 2022 - Nonalcoholic fatty liver disease (NAFLD) is well recognized as a leading etiology for chronic liver disease, affecting >25% of the US and global populations. Up to 1 in 4 individuals with NAFLD have nonalcoholic steatohepatitis, which is associated with significant morbidity and mortality due to complications of liver cirrhosis, hepatic decompensation, and hepatocellular carcinoma. Although NAF...

Management of Hyperglycemia in Hospitalized Adult Patients in Non-Critical Care Setting...
https://doi.org/10.1210/clinem/dgac278
The Journal of Clinical Endocrinology and Metabolism; Korytkowski MT, Muniyappa R et. al.

Jun 13th, 2022 - Adult patients with diabetes or newly recognized hyperglycemia account for over 30% of noncritically ill hospitalized patients. These patients are at increased risk for adverse clinical outcomes in the absence of defined approaches to glycemic management. To review and update the 2012 Management of Hyperglycemia in Hospitalized Patients in Non-Critical Care Settings: An Endocrine Society Clinic...

Aspirin Use to Prevent Cardiovascular Disease: US Preventive Services Task Force Recomm...
https://doi.org/10.1001/jama.2022.4983
JAMA , Davidson KW et. al.

Apr 27th, 2022 - Cardiovascular disease (CVD) is the leading cause of mortality in the US, accounting for more than 1 in 4 deaths. Each year, an estimated 605 000 people in the US have a first myocardial infarction and an estimated 610 000 experience a first stroke. To update its 2016 recommendation, the US Preventive Services Task Force (USPSTF) commissioned a systematic review on the effectiveness of aspirin ...

Heart Rhythm Society Atrial Fibrillation Centers of Excellence Study: A survey analysis...
https://doi.org/10.1016/j.hrthm.2022.02.022
Heart Rhythm; Sandhu RK, Seiler A et. al.

Apr 17th, 2022 - An integrated, coordinated, and patient-centered approach to atrial fibrillation (AF) care delivery may improve outcomes and reduce cost. The purpose of this study was to gain a better understanding from key stakeholder groups on current practices, needs, and potential barriers to implementing optimal integrated AF care. A series of comprehensive questionnaires were designed by the Heart Rhythm...

American College of Gastroenterology-Canadian Association of Gastroenterology Clinical ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8966740
The American Journal of Gastroenterology; Abraham NS, Barkun AN et. al.

Mar 18th, 2022 - We conducted systematic reviews of predefined clinical questions and used the Grading of Recommendations, Assessment, Development and Evaluations approach to develop recommendations for the periendoscopic management of anticoagulant and antiplatelet drugs during acute gastrointestinal (GI) bleeding and the elective endoscopic setting. The following recommendations target patients presenting wit...

AGA Clinical Practice Update on De-Prescribing of Proton Pump Inhibitors: Expert Review.
https://doi.org/10.1053/j.gastro.2021.12.247
Gastroenterology Targownik LE, Fisher DA et. al.

Feb 21st, 2022 - Proton pump inhibitors (PPIs) are among the most commonly used medications in the world. Developed for the treatment and prevention of acid-mediated upper gastrointestinal conditions, these agents are being used increasingly for indications where their benefits are less certain. PPI overprescription imposes an economic cost and contributes to polypharmacy. In addition, PPI use has been increasi...

Regional anaesthesia in patients on antithrombotic drugs: Joint ESAIC/ESRA guidelines.
https://doi.org/10.1097/EJA.0000000000001600
European Journal of Anaesthesiology; Kietaibl S, Ferrandis R et. al.

Jan 5th, 2022 - Bleeding is a potential complication after neuraxial and peripheral nerve blocks. The risk is increased in patients on antiplatelet and anticoagulant drugs. This joint guideline from the European Society of Anaesthesiology and Intensive Care and the European Society of Regional Anaesthesia aims to provide an evidence-based set of recommendations and suggestions on how to reduce the risk of anti...

Antiseizure Medication Withdrawal in Seizure-Free Patients: Practice Advisory Update Su...
https://doi.org/10.1212/WNL.0000000000012944
Neurology Gloss D, Pargeon K et. al.

Dec 8th, 2021 - To update a 1996 American Academy of Neurology practice parameter. The authors systematically reviewed literature published from January 1991 to March 2020. The long-term (24-60 months) risk of seizure recurrence is possibly higher among adults who have been seizure-free for 2 years and taper antiseizure medications (ASMs) vs those who do not taper ASMs (15% vs 7% per the 1 Class I article addr...

Management of Pyrexia Associated with the Combination of Dabrafenib and Trametinib: Can...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8482100
Current Oncology (Toronto, Ont.); Thawer A, Miller WH et. al.

Oct 1st, 2021 - The combination of dabrafenib and trametinib is a well-established treatment for BRAF-mutated melanoma. However, the effectiveness of this approach may be hindered by the development of treatment-related pyrexia syndrome, which occurs in at least 50% of treated patients. Without appropriate intervention, pyrexia syndrome has the potential to worsen and can result in hypotension secondary to deh...

AGA Clinical Practice Guideline on the Management of Coagulation Disorders in Patients ...
https://doi.org/10.1053/j.gastro.2021.08.015
Gastroenterology O'Shea RS, Davitkov P et. al.

Sep 29th, 2021 - AGA Clinical Practice Guideline on the Management of Coagulation Disorders in Patients With Cirrhosis.|2021|O'Shea RS,Davitkov P,Ko CW,Rajasekhar A,Su GL,|adverse effects,therapeutic use,drug effects,blood,diagnosis,drug therapy,standards,chemically induced,blood,diagnosis,drug therapy,

AGA Technical Review on Coagulation in Cirrhosis.
https://doi.org/10.1053/j.gastro.2021.09.004
Gastroenterology Intagliata NM, Davitkov P et. al.

Sep 29th, 2021 - AGA Technical Review on Coagulation in Cirrhosis.|2021|Intagliata NM,Davitkov P,Allen AM,Falck-Ytter YT,Stine JG,|adverse effects,therapeutic use,drug effects,blood,diagnosis,drug therapy,standards,chemically induced,blood,diagnosis,drug therapy,

Late hepatic toxicity surveillance for survivors of childhood, adolescent and young adu...
https://doi.org/10.1016/j.ctrv.2021.102296
Cancer Treatment Reviews; Bardi E, Mulder RL et. al.

Sep 28th, 2021 - Survivors of childhood, adolescent and young adult (CAYA) cancer may develop treatment-induced chronic liver disease. Surveillance guidelines can improve survivors' health outcomes. However, current recommendations vary, leading to uncertainty about optimal screening. The International Late Effects of Childhood Cancer Guideline Harmonization Group has developed recommendations for the surveilla...

ACG Clinical Guideline: Diagnosis and Management of Idiosyncratic Drug-Induced Liver In...
https://doi.org/10.14309/ajg.0000000000001259
The American Journal of Gastroenterology; Chalasani NP, Maddur H et. al.

May 1st, 2021 - Idiosyncratic drug-induced liver injury (DILI) is common in gastroenterology and hepatology practices, and it can have multiple presentations, ranging from asymptomatic elevations in liver biochemistries to hepatocellular or cholestatic jaundice, liver failure, or chronic hepatitis. Antimicrobials, herbal and dietary supplements, and anticancer therapeutics (e.g., tyrosine kinase inhibitors or ...

Guideline No. 417: Prevention of Venous Thromboembolic Disease in Gynaecological Surgery.
https://doi.org/10.1016/j.jogc.2021.04.003
Journal of Obstetrics and Gynaecology Canada : JOGC = Jou... Tafler K, Kuriya A et. al.

Apr 21st, 2021 - The primary objective of this clinical practice guideline is to provide gynaecologists with an algorithm and evidence to guide the use of thromboprophylaxis in gynaecological surgery. All patients undergoing gynaecological surgery for benign or malignant indications. The implementation of this guideline will benefit patients undergoing gynaecological surgery and provide physicians with a standa...

The Use of Contrast Agents in Interventional Pain Procedures: A Multispecialty and Mult...
https://doi.org/10.1213/ANE.0000000000005443
Anesthesia and Analgesia; Benzon HT, Maus TP et. al.

Mar 24th, 2021 - This Practice Advisory presents a comprehensive and evidence-based set of position statements and recommendations for the use of contrast media in interventional pain procedures. The advisory was established by an international panel of experts under the auspices of 11 multinational and multispecialty organizations based on a comprehensive review of the literature up to December 31, 2019. The a...

2021 Update of the International Council for Standardization in Haematology Recommendat...
https://doi.org/10.1055/a-1450-8178
Thrombosis and Haemostasis; Douxfils J, Adcock DM et. al.

Mar 21st, 2021 - In 2018, the International Council for Standardization in Haematology (ICSH) published a consensus document providing guidance for laboratories on measuring direct oral anticoagulants (DOACs). Since that publication, several significant changes related to DOACs have occurred, including the approval of a new DOAC by the Food and Drug Administration, betrixaban, and a specific DOAC reversal agent...

Prevention and treatment of anticipatory chemotherapy-induced nausea and vomiting in pe...
https://doi.org/10.1002/pbc.28947
Pediatric Blood & Cancer; Patel P, Robinson PD et. al.

Mar 10th, 2021 - This 2021 clinical practice guideline update provides recommendations for preventing anticipatory chemotherapy-induced nausea and vomiting (CINV) in pediatric patients. Recommendations are based on systematic reviews that identified (1) if a history of acute or delayed CINV is a risk factor for anticipatory CINV, and (2) interventions for anticipatory CINV prevention and treatment. A strong rec...

American College of Rheumatology, American Academy of Dermatology, Rheumatologic Dermat...
https://doi.org/10.1002/art.41683
Arthritis & Rheumatology (Hoboken, N.J.); Rosenbaum JT, Costenbader KH et. al.

Feb 10th, 2021 - Four major medical societies involved with hydroxychloroquine (HCQ) therapy concur on the need for common principles and cooperation to minimize the risk of ocular toxicity. At a daily dosage of ≤5 mg/kg/day actual body weight, the risk of retinal toxicity from HCQ is <2% for usage up to 10 years. Widespread adoption of more sensitive testing techniques, such as optical coherence tomography and...

Clinical Consensus Statement: Association of Anticholinergic Medication Use and Cogniti...
https://doi.org/10.1097/SPV.0000000000001008
Female Pelvic Medicine & Reconstructive Surgery;

Jan 27th, 2021 - Overactive bladder affects a significant portion of the overall population and has substantial impact on daily activities and quality of life. First-line treatment of overactive bladder includes behavioral therapies, which may be combined with pharmacologic management as indicated. Anticholinergic medications and β-3 agonists are often used as initial pharmacologic therapy, but caution should b...