National Institutes of Health (NIH)
Mar 3rd, 2021 - Tocilizumab is a recombinant humanized anti-interleukin (IL)-6 receptor monoclonal antibody approved by the Food and Drug Administration (FDA) for the treatment of certain rheumatologic disorders and cytokine release syndrome induced by chimeric antigen receptor T cell (CAR-T cell) therapy. It is hypothesized that modulating the levels of proinflammatory IL-6 or its effects may reduce the durat...
Aug 29th, 2017 - This guideline provides direction for clinicians and patients making treatment decisions. Clinicians and patients should use a shared decisionmaking process that accounts for patients’ values, preferences, and comorbidities.
J. Douglas Rizzo
Nov 5th, 2010 - For patients undergoing myelosuppressive chemotherapy who have a hemoglobin (Hb) level less than 10 g/dL, the Update Committee recommends that clinicians discuss potential harms (eg, thromboembolism, shorter survival) and benefits (eg, decreased transfusions) of ESAs and compare these with potential harms (eg, serious infections, immune-mediated adverse reactions) and benefits (eg, rapid Hb imp.
Jun 12th, 2012 - The American Thyroid Association today released a policy statement aiming to inform the public and healthcare practitioners about how to minimize risks to the thyroid gland associated with radiation exposure from diagnostic medical and dental radiography. Radiation exposure to the thyroid among both children and adults is currently the strongest known risk factor for thyroid cancer.
Jan 11th, 2018 - Induced pluripotent stem cells (iPSCs) offer an unprece-dented opportunity to study human physiology and disease at the cellular level. They also have the potential to be leveraged in the practice of precision medicine, for example, personalized drug testing.
Jonathan P. Parsons
Apr 30th, 2013 - Exercise-induced bronchoconstriction (EIB) describes acute airway narrowing that occurs as a result of exercise. A substantial proportion of patients with asthma experience exercise-induced respiratory symptoms.
Susan M. Tarlo, Jean-Luc Malo
Jul 31st, 2013 - Work-related asthma is a common occupational lung disease. The scope of the Fourth Jack Pepys Workshop that was held in May 2010 went beyond asthma to include discussion of other occupational airway diseases, in particular occupationally related chronic obstructive pulmonary disease (COPD) and bronchiolitis.
Dec 31st, 2008 - Moderate Sedation and Analgesia medications are frequently administered by Imaging Nurses. Moderate Sedation and Analgesia is defined as a drug‐induced depression of consciousness during which patients respond purposefully to verbal commands, either alone or accompanied by light tactile stimulation.
American Society of Anesthesiologists (ASA)
Oct 16th, 2018 - Moderate Sedation/Analgesia (Conscious Sedation, hereinafter known as Moderate Sedation) is a physician service recognized in the CPT procedural coding system. During Moderate Sedation, a physician supervises or personally administers sedative and/or analgesic medications that can allay patient anxiety and control pain during a diagnostic or therapeutic procedure.
Mar 31st, 2017 - These are the first international evidence-based guidelines to improve the diagnosis and management of patients with FPIES.
Nov 26th, 2018 - Background: Heparin-induced thrombocytopenia (HIT) is an adverse drug reaction mediated by platelet-activating antibodies that target complexes of platelet factor 4 and heparin. Patients are at markedly increased risk of thromboembolism.
Paul J. Hesketh
Sep 30th, 2017 - Key updates include the addition of olanzapine to antiemetic regimens for adults who receive high-emetic-risk antineoplastic agents or who experience breakthrough nausea and vomiting, a recommendation to administer dexamethasone on day 1 only for adults who receive anthracycline and cyclophosphamide chemotherapy, and the addition of a neurokinin 1 receptor antagonist for adults who receive carb.
Argoff, C.,et al
Nov 30th, 2015 - Aims of this consensus panel were to determine (1) an optimal symptom-based method for assessing opioid-induced constipation in clinical practice and (2) a threshold of symptom severity to prompt consideration of prescription therapy. A multidisciplinary panel of 10 experts with extensive knowledge/experience with opioid-associated adverse events convened to discuss the literature on assessment.
Jun 30th, 2018 - Health care providers should initiate the discussion on the possibility of infertility with patients with cancer treated during their reproductive years or with parents/guardians of children as early as possible. Providers should be prepared to discuss fertility preservation options and/or to refer all potential patients to appropriate reproductive specialists.
Juan Carlos Plana
Aug 31st, 2014 - Cardiac dysfunction resulting from exposure to cancer therapeutics was first recognized in the 1960s, with the widespread introduction of anthracyclines into the oncologic therapeutic armamentarium. Heart failure (HF) associated with anthracyclines was then recognized as an important side effect.
Mar 8th, 2016 - This clinical practice guideline provides an approach to the treatment of breakthrough chemotherapy‐induced nausea and vomiting (CINV) and the prevention of refractory CINV in children. It was developed by an international, interprofessional panel and is based on systematic literature reviews.
Berger, M.,et al
Jun 30th, 2017 - The NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) for Antiemesis address all aspects of management for chemotherapy-induced nausea and vomiting. These NCCN Guidelines Insights focus on recent updates to the NCCN Guidelines for Antiemesis, specifically those regarding carboplatin, granisetron, and olanzapine.
Dayna S. Early
Jan 2nd, 2018 - Sedation is a drug-induced depression in the level of consciousness. The clinical objectives of administering sedation for GI endoscopy are to relieve patient anxiety and discomfort, improve the outcome of the examination, and diminish the patient’s memory of the event.
Timothy I. Morgenthaler
Sep 30th, 2015 - The expanding science of circadian rhythm biology and a growing literature in human clinical research on circadian rhythm sleep disorders (CRSDs) prompted the American Academy of Sleep Medicine (AASM) to convene a task force of experts to write a review of this important topic. Due to the extensive nature of the disorders covered, the review was written in two sections.
William M. Lee
Feb 29th, 2012 - Acute liver failure (ALF) is a rare condition in which rapid deterioration of liver function results in altered mentation and coagulopathy in individuals without known pre-existing liver disease. U.