Journal of Thrombosis and Haemostasis : JTH; Iba T, Levi M et. al.
Jan 26th, 2023 - Disseminated intravascular coagulation (DIC) is a life-threatening complication in sepsis and other critical conditions. The International Society on Thrombosis and Haemostasis (ISTH) released the diagnostic criteria for overt DIC in 2001. Since then, ISTH overt DIC has been used as the global standard criterion for a decompensated stage of DIC. Because detecting an earlier stage of DIC would b...
Journal of Thrombosis and Haemostasis : JTH; Iba T, Levy JH et. al.
Jan 26th, 2023 - Disseminated intravascular coagulation (DIC) is not a disease criterion but a pathomechanistic process that accompanies various underlying diseases. According to the International Society on Thrombosis and Haemostasis definition, endothelial injury is an essential component in addition to systemic coagulation activation. Despite this definition, current diagnostic criteria for DIC do not includ...
The Journal of Clinical Endocrinology and Metabolism; McCall AL, Lieb DC et. al.
Dec 9th, 2022 - Hypoglycemia in people with diabetes is common, especially in those taking medications such as insulin and sulfonylureas (SU) that place them at higher risk. Hypoglycemia is associated with distress in those with diabetes and their families, medication nonadherence, and disruption of life and work, and it leads to costly emergency department visits and hospitalizations, morbidity, and mortality...
MMWR. Recommendations and Reports : Morbidity and Mortali... Dowell D, Ragan KR et. al.
Nov 4th, 2022 - This guideline provides recommendations for clinicians providing pain care, including those prescribing opioids, for outpatients aged ≥18 years. It updates the CDC Guideline for Prescribing Opioids for Chronic Pain - United States, 2016 (MMWR Recomm Rep 2016;65[No. RR-1]:1-49) and includes recommendations for managing acute (duration of <1 month), subacute (duration of 1-3 months), and chronic ...
Pediatric Blood & Cancer; Patel P, Robinson PD et. al.
Oct 13th, 2022 - This clinical practice guideline provides recommendations for preventing acute and delayed phase chemotherapy-induced nausea and vomiting (CINV) in pediatric patients. The recommendations are based on two systematic reviews of randomized controlled trials evaluating interventions to prevent (1) acute phase CINV and (2) delayed phase CINV. Recommendations for acute phase and delayed phase CINV p...
Gastroenterology Green PHR, Paski S et. al.
Sep 23rd, 2022 - The purpose of this expert review is to summarize the diagnosis and management of refractory celiac disease. It will review evaluation of patients with celiac disease who have persistent or recurrent symptoms, differential diagnosis, nutritional support, potential therapeutic options, and surveillance for complications of this condition. This expert review was commissioned and approved by the A...
Gastroenterology Long MT, Noureddin M et. al.
Jul 17th, 2022 - Nonalcoholic fatty liver disease (NAFLD) is well recognized as a leading etiology for chronic liver disease, affecting >25% of the US and global populations. Up to 1 in 4 individuals with NAFLD have nonalcoholic steatohepatitis, which is associated with significant morbidity and mortality due to complications of liver cirrhosis, hepatic decompensation, and hepatocellular carcinoma. Although NAF...
The Journal of Clinical Endocrinology and Metabolism; Korytkowski MT, Muniyappa R et. al.
Jun 13th, 2022 - Adult patients with diabetes or newly recognized hyperglycemia account for over 30% of noncritically ill hospitalized patients. These patients are at increased risk for adverse clinical outcomes in the absence of defined approaches to glycemic management. To review and update the 2012 Management of Hyperglycemia in Hospitalized Patients in Non-Critical Care Settings: An Endocrine Society Clinic...
JAMA , Davidson KW et. al.
Apr 27th, 2022 - Cardiovascular disease (CVD) is the leading cause of mortality in the US, accounting for more than 1 in 4 deaths. Each year, an estimated 605 000 people in the US have a first myocardial infarction and an estimated 610 000 experience a first stroke. To update its 2016 recommendation, the US Preventive Services Task Force (USPSTF) commissioned a systematic review on the effectiveness of aspirin ...
Heart Rhythm; Sandhu RK, Seiler A et. al.
Apr 17th, 2022 - An integrated, coordinated, and patient-centered approach to atrial fibrillation (AF) care delivery may improve outcomes and reduce cost. The purpose of this study was to gain a better understanding from key stakeholder groups on current practices, needs, and potential barriers to implementing optimal integrated AF care. A series of comprehensive questionnaires were designed by the Heart Rhythm...
The American Journal of Gastroenterology; Abraham NS, Barkun AN et. al.
Mar 18th, 2022 - We conducted systematic reviews of predefined clinical questions and used the Grading of Recommendations, Assessment, Development and Evaluations approach to develop recommendations for the periendoscopic management of anticoagulant and antiplatelet drugs during acute gastrointestinal (GI) bleeding and the elective endoscopic setting. The following recommendations target patients presenting wit...
Gastroenterology Targownik LE, Fisher DA et. al.
Feb 21st, 2022 - Proton pump inhibitors (PPIs) are among the most commonly used medications in the world. Developed for the treatment and prevention of acid-mediated upper gastrointestinal conditions, these agents are being used increasingly for indications where their benefits are less certain. PPI overprescription imposes an economic cost and contributes to polypharmacy. In addition, PPI use has been increasi...
European Journal of Anaesthesiology; Kietaibl S, Ferrandis R et. al.
Jan 5th, 2022 - Bleeding is a potential complication after neuraxial and peripheral nerve blocks. The risk is increased in patients on antiplatelet and anticoagulant drugs. This joint guideline from the European Society of Anaesthesiology and Intensive Care and the European Society of Regional Anaesthesia aims to provide an evidence-based set of recommendations and suggestions on how to reduce the risk of anti...
Neurology Gloss D, Pargeon K et. al.
Dec 8th, 2021 - To update a 1996 American Academy of Neurology practice parameter. The authors systematically reviewed literature published from January 1991 to March 2020. The long-term (24-60 months) risk of seizure recurrence is possibly higher among adults who have been seizure-free for 2 years and taper antiseizure medications (ASMs) vs those who do not taper ASMs (15% vs 7% per the 1 Class I article addr...
Current Oncology (Toronto, Ont.); Thawer A, Miller WH et. al.
Oct 1st, 2021 - The combination of dabrafenib and trametinib is a well-established treatment for BRAF-mutated melanoma. However, the effectiveness of this approach may be hindered by the development of treatment-related pyrexia syndrome, which occurs in at least 50% of treated patients. Without appropriate intervention, pyrexia syndrome has the potential to worsen and can result in hypotension secondary to deh...
Gastroenterology O'Shea RS, Davitkov P et. al.
Sep 29th, 2021 - AGA Clinical Practice Guideline on the Management of Coagulation Disorders in Patients With Cirrhosis.|2021|O'Shea RS,Davitkov P,Ko CW,Rajasekhar A,Su GL,|adverse effects,therapeutic use,drug effects,blood,diagnosis,drug therapy,standards,chemically induced,blood,diagnosis,drug therapy,
Gastroenterology Intagliata NM, Davitkov P et. al.
Sep 29th, 2021 - AGA Technical Review on Coagulation in Cirrhosis.|2021|Intagliata NM,Davitkov P,Allen AM,Falck-Ytter YT,Stine JG,|adverse effects,therapeutic use,drug effects,blood,diagnosis,drug therapy,standards,chemically induced,blood,diagnosis,drug therapy,
Cancer Treatment Reviews; Bardi E, Mulder RL et. al.
Sep 28th, 2021 - Survivors of childhood, adolescent and young adult (CAYA) cancer may develop treatment-induced chronic liver disease. Surveillance guidelines can improve survivors' health outcomes. However, current recommendations vary, leading to uncertainty about optimal screening. The International Late Effects of Childhood Cancer Guideline Harmonization Group has developed recommendations for the surveilla...
The American Journal of Gastroenterology; Chalasani NP, Maddur H et. al.
May 1st, 2021 - Idiosyncratic drug-induced liver injury (DILI) is common in gastroenterology and hepatology practices, and it can have multiple presentations, ranging from asymptomatic elevations in liver biochemistries to hepatocellular or cholestatic jaundice, liver failure, or chronic hepatitis. Antimicrobials, herbal and dietary supplements, and anticancer therapeutics (e.g., tyrosine kinase inhibitors or ...
Journal of Obstetrics and Gynaecology Canada : JOGC = Jou... Tafler K, Kuriya A et. al.
Apr 21st, 2021 - The primary objective of this clinical practice guideline is to provide gynaecologists with an algorithm and evidence to guide the use of thromboprophylaxis in gynaecological surgery. All patients undergoing gynaecological surgery for benign or malignant indications. The implementation of this guideline will benefit patients undergoing gynaecological surgery and provide physicians with a standa...