JAMA , Davidson KW et. al.
Sep 29th, 2021 - Preeclampsia is one of the most serious health problems that affect pregnant persons. It is a complication in approximately 4% of pregnancies in the US and contributes to both maternal and infant morbidity and mortality. Preeclampsia also accounts for 6% of preterm births and 19% of medically indicated preterm births in the US. There are racial and ethnic disparities in the prevalence of and mo...
BMJ (Clinical Research Ed.); Busse JW, Vankrunkelsven P et. al.
Sep 10th, 2021 - What is the role of medical cannabis or cannabinoids for people living with chronic pain due to cancer or non-cancer causes? Chronic pain is common and distressing and associated with considerable socioeconomic burden globally. Medical cannabis is increasingly used to manage chronic pain, particularly in jurisdictions that have enacted policies to reduce use of opioids; however, existing guidel...
Sep 9th, 2021 - This technical report accompanies the recommendations of the American Academy of Pediatrics for the routine use of the influenza vaccine and antiviral medications in the prevention and treatment of influenza in children during the 2021-2022 season. Influenza vaccination is an important intervention to protect vulnerable populations and reduce the burden of respiratory illnesses during circulati...
Clinical Chemistry; Zhang YV, Wiencek J et. al.
Sep 2nd, 2021 - The clinical laboratory continues to play a critical role in managing the coronavirus pandemic. Numerous US Food and Drug Administration emergency use authorization (EUA) and laboratory-developed test (LDT) serologic assays have become available. The performance characteristics of these assays and their clinical utility continue to be defined in real time during this pandemic. The AACC convened...
The Journal of Family Practice; Murphy KR, Solis J
Aug 26th, 2021 - • The 2020 Focused Updates to the Asthma Management Guidelines: A Report from the National Asthma Education and Prevention Program Coordinating Committee Expert Panel Working Group provides updated recommendations for 6 topics related to the management of individuals with asthma. • The classification of asthma severity and asthma control, as well as the concept of utilizing a stepwise approach ...
European Journal of Endocrinology; Bartalena L, Kahaly GJ et. al.
Jul 24th, 2021 - Graves' orbitopathy (GO) is the main extrathyroidal manifestation of Graves' disease (GD). Choice of treatment should be based on the assessment of clinical activity and severity of GO. Early referral to specialized centers is fundamental for most patients with GO. Risk factors include smoking, thyroid dysfunction, high serum level of thyrotropin receptor antibodies, radioactive iodine (RAI) tr...
MMWR. Recommendations and Reports : Morbidity and Mortali... Nelson CA, Meaney-Delman D et. al.
Jul 16th, 2021 - This report provides CDC recommendations to U.S. health care providers regarding treatment, pre-exposure prophylaxis, and postexposure prophylaxis of plague. Yersinia pestis, the bacterium that causes plague, leads to naturally occurring disease in the United States and other regions worldwide and is recognized as a potential bioterrorism weapon. A bioweapon attack with Y. pestis could potentia...
Respiration; International Review of Thoracic Diseases; Renda T, Scala R et. al.
Jun 9th, 2021 - The imbalance between the prevalence of patients with acute respiratory failure (ARF) and acute-on-chronic respiratory failure and the number of intensive care unit (ICU) beds requires new solutions. The increasing use of non-invasive respiratory tools to support patients at earlier stages of ARF and the increased expertise of non-ICU clinicians in other types of supportive care have led to the...
The Canadian Journal of Cardiology; Paterson I, Ramanathan K et. al.
Jun 7th, 2021 - It is now widely recognized that COVID-19 illness can be associated with significant intermediate and potentially longer-term physical limitations. The term, "long COVID-19" is used to define any patient with persistent symptoms after acute COVID-19 infection (ie, after 4 weeks). It is postulated that cardiac injury might be linked to symptoms that persist after resolution of acute infection, a...
Journal of the American College of Cardiology; Willett J, Achenbach S et. al.
May 31st, 2021 - The Tobacco Endgame: Eradicating a Worsening Epidemic A Joint Opinion From the American Heart Association, World Heart Federation, American College of Cardiology, and the European Society of Cardiology.|2021|Willett J,Achenbach S,Pinto FJ,Poppas A,Elkind MSV,|methods,trends,methods,methods,organization & administration,epidemiology,prevention & control,psychology,
MMWR. Morbidity and Mortality Weekly Report; Curtis KM, Nguyen A et. al.
May 21st, 2021 - U.S. Selected Practice Recommendations for Contraceptive Use (U.S. SPR), adapted by CDC from global guidance developed by the World Health Organization (WHO), provides evidence-based guidance on contraceptive use for U.S. health care providers (1). During January-February, 2021, CDC evaluated the 2019 WHO recommendation on self-administered subcutaneous depot medroxyprogesterone acetate (DMPA-S...
Cancer Science; Minami H, Kiyota N et. al.
May 16th, 2021 - Clinical studies intended for regulatory approval must demonstrate the clinical benefits of the drug in a target population. Clinical development of a drug proceeds by stepwise clinical studies; after safety and pharmacokinetics are evaluated and the recommended dosage and administration are determined, efficacy and safety are evaluated in an exploratory manner, and finally clinical benefits ar...
The Journal of Thoracic and Cardiovascular Surgery; , Ommen SR et. al.
May 1st, 2021 - 2020 AHA/ACC guideline for the diagnosis and treatment of patients with hypertrophic cardiomyopathy: A report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines.|2021| ,Ommen SR,Mital S,Burke MA,Day SM,|organization & administration,diagnosis,therapy,
Journal of the American College of Cardiology; , Généreux P et. al.
Apr 24th, 2021 - The Valve Academic Research Consortium (VARC), founded in 2010, was intended to (i) identify appropriate clinical endpoints and (ii) standardize definitions of these endpoints for transcatheter and surgical aortic valve clinical trials. Rapid evolution of the field, including the emergence of new complications, expanding clinical indications, and novel therapy strategies have mandated further r...
British Journal of Anaesthesia; Srivastava D, Hill S et. al.
Apr 19th, 2021 - There are significant concerns regarding prescription and misuse of prescription opioids in the perioperative period. The Faculty of Pain Medicine at the Royal College of Anaesthetists have produced this evidence-based expert consensus guideline on surgery and opioids along with the Royal College of Surgery, Royal College of Psychiatry, Royal College of Nursing, and the British Pain Society. Th...
BMJ Sexual & Reproductive Health; Gilmore KL, Hardman SM
Apr 15th, 2021 - New FSRH guideline on the progestogen-only implant.|2021|Gilmore KL,Hardman SM,|trends,therapeutic use,organization & administration,trends,
Annals of Hematology; Classen AY, Henze L et. al.
Apr 14th, 2021 - Hematologic and oncologic patients with chemo- or immunotherapy-related immunosuppression are at substantial risk for bacterial infections and Pneumocystis jirovecii pneumonia (PcP). As bacterial resistances are increasing worldwide and new research reshapes our understanding of the interactions between the human host and bacterial commensals, administration of antibacterial prophylaxis has bec...
Fertility and Sterility;
Apr 12th, 2021 - This document provides the latest recommendations for the evaluation of potential sperm, oocyte, and embryo donors as well as their recipients, incorporating recent information about optimal screening and testing for sexually transmitted infections, genetic diseases, and psychological assessments. This revised document incorporates recent information from the US Centers for Disease Control and ...
Annals of Internal Medicine; Lee RA, Centor RM et. al.
Apr 6th, 2021 - Antimicrobial overuse is a major health care issue that contributes to antibiotic resistance. Such overuse includes unnecessarily long durations of antibiotic therapy in patients with common bacterial infections, such as acute bronchitis with chronic obstructive pulmonary disease (COPD) exacerbation, community-acquired pneumonia (CAP), urinary tract infections (UTIs), and cellulitis. This artic...
Clinical Gastroenterology and Hepatology : the Official C... Ahmed O, Lee JH et. al.
Apr 5th, 2021 - The purpose of this expert review is to describe the current methodologies available to manage malignant alimentary tract obstructions as well the evidence behind the various methods (including their efficacy and safety), indications, and appropriate timing of interventions. This is not a formal systematic review but is based on a review of the literature to provide best practice advice stateme...