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About 35 results

SEOM clinical guidelines for the treatment of malignant pleural mesothelioma (2020).
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8057959
Clinical & Translational Oncology : Official Publication ... Nadal E, Bosch-Barrera J et. al.

Feb 5th, 2021 - Mesothelioma is a rare and aggressive tumour with dismal prognosis arising in the pleura and associated with asbestos exposure. Its incidence is on the rise worldwide. In selected patients with early-stage MPM, a maximal surgical cytoreduction in combination with additional antitumour treatment may be considered in selected patients assessed by a multidisciplinary tumor board. In patients with ...

Chemical carcinogen safety testing: OECD expert group international consensus on the de...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7395040
Archives of Toxicology; Jacobs MN, Colacci A et. al.

Jul 1st, 2020 - While regulatory requirements for carcinogenicity testing of chemicals vary according to product sector and regulatory jurisdiction, the standard approach starts with a battery of genotoxicity tests (which include mutagenicity assays). If any of the in vivo genotoxicity tests are positive, a lifetime rodent cancer bioassay may be requested, but under most chemical regulations (except plant prot...

Guideline at a Glance: Surgical Smoke.
https://doi.org/10.1016/S0001-2092(16)31044-4
AORN Journal;

Feb 6th, 2017 - Guideline at a Glance: Surgical Smoke.|2017| ,|toxicity,adverse effects,prevention & control,adverse effects,methods,

Pediatric gastrointestinal endoscopy: European Society of Gastrointestinal Endoscopy (E...
https://doi.org/10.1055/s-0042-111002
Endoscopy Tringali A, Thomson M et. al.

Sep 13th, 2016 - This Executive summary of the Guideline on pediatric gastrointestinal endoscopy from the European Society of Gastrointestinal Endoscopy (ESGE) and the European Society for Paediatric Gastroenterology Hepatology and Nutrition (ESPGHAN) refers to infants, children, and adolescents aged 0 - 18 years. The areas covered include: indications for diagnostic and therapeutic esophagogastroduodenoscopy a...

Prevention of Childhood Lead Toxicity.
https://doi.org/10.1542/peds.2016-1493
Pediatrics

Jun 22nd, 2016 - Blood lead concentrations have decreased dramatically in US children over the past 4 decades, but too many children still live in housing with deteriorated lead-based paint and are at risk for lead exposure with resulting lead-associated cognitive impairment and behavioral problems. Evidence continues to accrue that commonly encountered blood lead concentrations, even those below 5 µg/dL (50 pp...

Recommendations on Screening for Chloroquine and Hydroxychloroquine Retinopathy (2016 R...
https://doi.org/10.1016/j.ophtha.2016.01.058
Ophthalmology Marmor MF, Kellner U et. al.

Mar 20th, 2016 - The American Academy of Ophthalmology recommendations on screening for chloroquine (CQ) and hydroxychloroquine (HCQ) retinopathy are revised in light of new information about the prevalence of toxicity, risk factors, fundus distribution, and effectiveness of screening tools. Although the locus of toxic damage is parafoveal in many eyes, Asian patients often show an extramacular pattern of damag...

Agricultural Applications for Antimicrobials. A Danger to Human Health: An Official Pos...
https://doi.org/10.1002/phar.1737
Pharmacotherapy Aitken SL, Dilworth TJ et. al.

Mar 10th, 2016 - The use of antibiotics in agriculture, particularly in food-producing animals, is pervasive and represents the overwhelming majority of antibiotic use worldwide. The link between antibiotic use in animals and antibiotic resistance in humans is unequivocal. Transmission can occur by ingesting undercooked meats harboring resistant bacteria, by direct contact of animals by animal handlers, and by ...

Assessment of learning, memory, and attention in developmental neurotoxicity regulatory...
https://doi.org/10.1016/j.ntt.2015.10.004
Neurotoxicology and Teratology; Vorhees CV, Makris SL

Nov 4th, 2015 - Cognitive tests of learning and memory (L&M) have been required by U.S. Environmental Protection Agency (EPA) developmental neurotoxicity test (DNT) guidelines for more than two decades. To evaluate the utility of these guidelines, the EPA reviewed 69 pesticide DNT studies. This review found that the DNT provided or could provide the point-of-departure for risk assessment by showing the Lowest ...

Diagnosis and management of acquired aplastic anemia in childhood. Guidelines from the ...
https://doi.org/10.1016/j.bcmd.2015.03.007
Blood Cells, Molecules & Diseases; Barone A, Lucarelli A et. al.

May 16th, 2015 - Acquired aplastic anemia (AA) is a rare heterogeneous disease characterized by pancytopenia and hypoplastic bone marrow. The incidence is 2-3/million inhabitants/year, in Europe, but higher in East Asia. Survival in severe aplastic anemia (SAA) has markedly improved in the past 2 decades because of advances in hematopoietic stem cell transplantation, immunosuppressive and biologic drugs, and su...

2012 Update: World Allergy Organization Guidelines for the assessment and management of...
https://doi.org/10.1097/ACI.0b013e328355b7e4
Current Opinion in Allergy and Clinical Immunology; Simons FE, Ardusso LR et. al.

Jun 30th, 2012 - The World Allergy Organization (WAO) Guidelines for the assessment and management of anaphylaxis published in early 2011 provide a global perspective on patient risk factors, triggers, clinical diagnosis, treatment, and prevention of anaphylaxis. In this 2012 Update, subsequently published, clinically relevant research in these areas is reviewed. Patient risk factors and co-factors that amplify...

Unified treatment algorithm for the management of crotaline snakebite in the United Sta...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3042971
BMC Emergency Medicine; Lavonas EJ, Ruha AM et. al.

Feb 5th, 2011 - Envenomation by crotaline snakes (rattlesnake, cottonmouth, copperhead) is a complex, potentially lethal condition affecting thousands of people in the United States each year. Treatment of crotaline envenomation is not standardized, and significant variation in practice exists. A geographically diverse panel of experts was convened for the purpose of deriving an evidence-informed unified treat...

Guidelines for the derivation of Biomonitoring Equivalents: report from the Biomonitori...
https://doi.org/10.1016/j.yrtph.2008.05.004
Regulatory Toxicology and Pharmacology : RTP; Hays SM, Aylward LL et. al.

Jun 28th, 2008 - Biomonitoring Equivalents (BEs) are defined as the concentration of a chemical (or metabolite) in a biological medium (blood, urine, human milk, etc.) consistent with defined exposure guidance values or toxicity criteria including reference doses and reference concentrations (RfD and RfCs), minimal risk levels (MRLs), or tolerable daily intakes (TDIs) [Hays, S.M., Becker, R.A., Leung, H.W., Ayl...

Guidelines for the communication of Biomonitoring Equivalents: report from the Biomonit...
https://doi.org/10.1016/j.yrtph.2008.05.007
Regulatory Toxicology and Pharmacology : RTP; LaKind JS, Aylward LL et. al.

Jun 27th, 2008 - Biomonitoring Equivalents (BEs) are screening tools for interpreting biomonitoring data. However, the development of BEs brings to the public a relatively novel concept in the field of health risk assessment and presents new challenges for environmental risk communication. This paper provides guidance on methods for conveying information to the general public, the health care community, regulat...

Management of cocaine-associated chest pain and myocardial infarction: a scientific sta...
https://doi.org/10.1161/CIRCULATIONAHA.107.188950
Circulation McCord J, Jneid H et. al.

Mar 19th, 2008 - Management of cocaine-associated chest pain and myocardial infarction: a scientific statement from the American Heart Association Acute Cardiac Care Committee of the Council on Clinical Cardiology.|2008|McCord J,Jneid H,Hollander JE,de Lemos JA,Cercek B,|therapeutic use,therapeutic use,chemically induced,pharmacology,toxicity,complications,diagnosis,epidemiology,drug effects,chemically induced,...