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FDA In Brief: FDA Issues Procedural Notice on Potential Plans to Conduct Research About Use of ‘Healthy’ Symbols on Food Products | FDA
https://www.fda.gov/news-events/press-announcements/fda-brief-fda-issues-procedural-notice-potential-plans-conduct-research-about-use-healthy-symbols

May 6th, 2021 - For Immediate Release: May 06, 2021 The following quote is attributed to Conrad Choiniere, Ph.D., director of the Office of Analytics and Outreach, Center for Food Safety and Applied Nutrition "The FDA understands that consumers want healthy choices when it comes to food and nutrition. Today, we are issuing a procedural notice on preliminary consumer research we are planning on the use of symbo...

COVID Delay of Treatment of Neovascular Age-Related Macular Degeneration Less Harmful Than Expected
https://www.medscape.com/viewarticle/950709

May 5th, 2021 - Many people with neovascular age-related macular degeneration (nAMD) lost less vision than expected during treatment delays imposed by COVID-19, researchers say. The finding suggests that physicians may be overtreating these patients, said James Talks, MB BChir, a consultant ophthalmologist at the Royal Victoria Infirmary in Newcastle upon Tyne, United Kingdom. But many patients with nAMD decid...

School-Based Asthma Program Improves Care for Kids
https://www.medscape.com/viewarticle/950672

May 5th, 2021 - Asthma care coordination for children can be improved through a school-based asthma program involving the child's school, their family, and clinicians, according to a recent presentation at the annual meeting of the American Academy of Allergy, Asthma, and Immunology, held virtually this year. "Partnerships among schools, families, and clinicians can be powerful agents to improve the recognitio...

Look Beyond Liver Biopsy for NAFLD Diagnosis
https://www.medscape.com/viewarticle/950690

May 5th, 2021 - Nonalcoholic fatty liver disease (NAFLD) was present in approximately two-thirds of patients who did not undergo a liver biopsy. These patients were more likely to be non-White and older, as well as have normal ALT levels, which shows potential gaps in knowledge about this population. Data from studies of patients diagnosed with NAFLD that require biopsy among their inclusion criteria may be su...

Vaping Linked to Visual Impairment
https://www.medscape.com/viewarticle/950633

May 5th, 2021 - People who use e-cigarettes have a high rate of visual impairment, researchers say, and that association is independent of and in addition to traditional cigarette use. The statistical correlation doesn't prove that vaping causes visual impairment. But it parallels earlier studies that link tobacco smoking to visual impairment, and vaping to lung damage. And it raises new questions about whethe...

 Sleep Disorders Linked to an Increased Risk of Osteoarthritis
https://www.medscape.com/viewarticle/950625

May 5th, 2021 - Takeaway Sleep disorders were significantly associated with an increased risk of osteoarthritis (OA). The association was significant across all sex, age and OA type subgroups, with the exception of patients aged >80 years and those with knee OA. Why this matters Findings highlight the importance of improving the diagnosis and management of sleep disorders to mitigate their potentially deleteri...

Going Viral: Social Media May Be Increasing Cases of New-Onset Tics
https://www.medscape.com/viewarticle/949882

May 5th, 2021 - This transcript has been edited for clarity. Kathrin LaFaver, MD: Hello. I'm Dr Kathrin LaFaver, a movement disorders specialist at Northwestern University here in Chicago. It is my great pleasure today to interview Dr Tamara Pringsheim on the topic of acute-onset explosive tic-like behaviors. Dr Pringsheim is an associate professor in the Department of Clinical Neurosciences, Psychiatry, Pedia...

Shorter Tuberculosis Regimen With Moxifloxacin Not Inferior to 6-Month Treatment
https://www.medscape.com/viewarticle/950608

May 5th, 2021 - NEW YORK (Reuters Health) - A new rifapentine-based regimen with moxifloxacin can shorten the treatment time for drug-susceptible pulmonary tuberculosis, the authors behind a new phase-3 test report. "This is the first time in 40 years wherein treatment shortening has been feasible for drug-susceptible TB, so this is a landmark event," coauthor Dr. Payam Nahid, director of the Center for Tuberc...

Moderna Announces First Data Showing Efficacy of COVID-19 Vaccine Booster in Development
https://www.medscape.com/viewarticle/950650

May 5th, 2021 - Find the latest COVID-19 news and guidance in Medscape's  Coronavirus Resource Center. The Moderna SARS-CoV-2 vaccine booster developed specifically with variant B. 1

Infective Endocarditis With Stroke After TAVR Has 'Dismal' Prognosis
https://www.medscape.com/viewarticle/950702

May 5th, 2021 - Patients who suffer a stroke during hospitalization for infective endocarditis (IE) after transcatheter aortic valve replacement (TAVR) have a dismal prognosis, with more than half dying during the index hospitalization and two thirds within the first year, a new study shows. The study — the first to evaluate stroke as an IE-related complication following TAVR in a large multicenter cohort — is...

COVID-19 Confinement May Have Caused Myopia in Kids
https://www.medscape.com/viewarticle/950711

May 5th, 2021 - The COVID-19 pandemic may have increased the prevalence of myopia by confining young children indoors, researchers say. Spending more time inside focused on computer screens appears to have most affected the eyesight of the youngest school children, said Xuehan Qian, MD, PhD, of Tianjin Medical University Eye Hospital in Tianjin, China. "We should be worried about the eye problems of COVID-19, ...

Nighttime Asthma Predicts Poor Outcomes in Teens
https://www.medscape.com/viewarticle/950658

May 5th, 2021 - Teens with persistent nocturnal asthma symptoms were significantly more likely than were those without nighttime asthma to report poor functional health independent of daytime asthma, based on data from 430 adolescents aged 12-16 years. Approximately half of children with severe asthma experience at least one night of inadequate sleep per week, and lost sleep among young children with asthma ha...

Progress Stalling on Malaria Elimination
https://www.medscape.com/viewarticle/950546

May 4th, 2021 - In its final report on the E-2020 initiative, the World Health Organization (WHO) touted its progress on its goal of eliminating malaria throughout the world. But critics are charging that progress has stalled. The E-2020 initiative supported the efforts of twenty-one countries in eliminating malaria. In a remarkable achievement, especially during the COVID-19 pandemic, eight E-2020 member coun...

Novel Drug Offers Rapid Relief From Agitation in Serious Mental Illness
https://www.medscape.com/viewarticle/950613

May 4th, 2021 - An investigational, orally dissolving film formulation of dexmedetomidine (BXCL501, BioXcel Therapeutics) may offer rapid relief from acute agitation related to schizophrenia or bipolar disorder (BD), results of two phase 3, randomized, placebo-controlled trials show. Dr Leslie Citrome For both disorders, BXCL501 showed "superiority over placebo" by meeting the primary endpoint of reduction of ...

COVID-19 Severity Starts in Normal BMI Range, Especially in Young
https://www.medscape.com/viewarticle/950568

May 4th, 2021 - Editor's note: Find the latest COVID-19 news and guidance in Medscape's Coronavirus Resource Center. The risk of severe outcomes with COVID-19 increases with excess weight in a linear manner beginning in normal body mass index ranges, with the effect apparently independent of obesity-related diseases such as diabetes and stronger among younger people and Black persons, new research shows. Risk ...

Tofacitinib: Small Study Shows Big Cutaneous Sarcoidosis Response
https://www.medscape.com/viewarticle/950598

May 4th, 2021 - Researchers are reporting impressive results in a small, open-label trial of the JAK inhibitor tofacitinib in cutaneous sarcoidosis: 6 of 10 patients improved so much that they reached a disease activity level of zero, and all patients improved by an average of 83% via a scoring system. "Not only did patients get better, but they were in many cases able to come off their baseline immunosuppress...

Fast Five Quiz: Squamous Cell Non-Small Cell Lung Cancer
https://reference.medscape.com/viewarticle/928233

May 4th, 2021 - Lung cancer continues to be the leading cause of cancer-related deaths worldwide. Non–small cell lung cancer (NSCLC), which accounts for 85% of all lung cancers, is divided histologically into adenocarcinoma, squamous cell carcinoma, and large cell carcinoma. In the United States, Canada, and many European countries, squamous cell carcinoma is the second most common histologic subtype of lung c...

For Diagnosing Skin Lesions, AI Risks Failing in Skin of Color
https://www.medscape.com/viewarticle/950572

May 4th, 2021 - In the analysis of images for detecting potential pathology, artificial intelligence (AI) is showing enormous promise across multiple fields of medicine. But the technology in dermatology is bound to fail in skin of color if training does not specifically address these skin types, according to Adewole S. Adamson, MD, who outlined this issue at the American Academy of Dermatology Virtual Meeting...

Therapeutic Drug Monitoring Has Little Value During Infliximab Induction
https://www.medscape.com/viewarticle/950456

May 4th, 2021 - NEW YORK (Reuters Health) - Results of a randomized controlled trial do not support routine use of proactive therapeutic drug monitoring (TDM) during infliximab induction for improving disease remission rates in patients with rheumatoid arthritis (RA) and other chronic immune-mediated inflammatory diseases. Proactive TDM tailors biologic therapy to individual patients by measuring serum drug le...

Corticosteroid Bursts May Increase GI Bleeding, Sepsis Risk in Children
https://www.medscape.com/viewarticle/950567

May 4th, 2021 - Oral corticosteroid bursts are associated with an increased risk of gastrointestinal bleeding, sepsis, and pneumonia during the month after treatment initiation, according to a nationwide cohort study of children in Taiwan. The adverse events are rare, and the risk attenuates in subsequent months, the analysis shows. Still, the study "provides evidence that corticosteroid bursts are not innocuo...