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 COVID-19 Vaccine Coverage and Effectiveness among Healthcare Workers in England

May 6th, 2021 - Takeaway In a cohort of healthcare workers in England, vaccine coverage was very high 2 months after the roll-out of approved COVID-19 vaccines in the UK.

FDA In Brief: FDA Issues Procedural Notice on Potential Plans to Conduct Research About Use of ‘Healthy’ Symbols on Food Products | FDA

May 6th, 2021 - For Immediate Release: May 06, 2021 The following quote is attributed to Conrad Choiniere, Ph.D., director of the Office of Analytics and Outreach, Center for Food Safety and Applied Nutrition "The FDA understands that consumers want healthy choices when it comes to food and nutrition. Today, we are issuing a procedural notice on preliminary consumer research we are planning on the use of symbo...

FDA Committee Votes to Withdraw Two Accelerated Approvals of Cancer Treatments

May 5th, 2021 - The U.S. Food and Drug Administration’s (FDA’s) Oncologic Drugs Advisory Committee (ODAC) recommended withdrawing two of six accelerated approvals of cancer treatments that it reevaluated in a recent meeting, citing the failure to verify benefit in follow-up trials. The committee voted 6-2 to withdraw the accelerated approval of pembrolizumab for the treatment of patients with recurrent locally...

Pipette Tip Shortage Hinders Scientific Work Worldwide

May 5th, 2021 - An ongoing pipette tip shortage caused by the COVID-19 pandemic, blackouts in Texas, and a manufacturing plant fire is hindering scientific work around the world, from newborn screening to drug development to basic research. While COVID-19 diagnostic tests’ reliance on pipette tips has contributed to the shortage, several other issues further up the supply chain have also played a role. Winter ...

UK COVID-19 Update: Strong Protection from Pfizer Jab and Vaccine Confidence Remains High

May 5th, 2021 - These are the UK coronavirus stories you need to know about today. A supplementary analysis showed that a single dose of the vaccine was associated with moderate protection against infection, hospitalisation, and death, emphasising the importance of fully vaccinating adults, the researchers said. They acknowledged remaining uncertainties about the duration of immunity, and the possible emergenc...

COVID Delay of Treatment of Neovascular Age-Related Macular Degeneration Less Harmful Than Expected

May 5th, 2021 - Many people with neovascular age-related macular degeneration (nAMD) lost less vision than expected during treatment delays imposed by COVID-19, researchers say. The finding suggests that physicians may be overtreating these patients, said James Talks, MB BChir, a consultant ophthalmologist at the Royal Victoria Infirmary in Newcastle upon Tyne, United Kingdom. But many patients with nAMD decid...

Should COVID Shots for Teens Go to Developing Countries?

May 5th, 2021 - Editor's note: Find the latest COVID-19 news and guidance in Medscape's Coronavirus Resource Center. U. S The administration announced plans in late April to send 60 million doses of the AstraZeneca vaccine to countries in need. But that won't be enough to help resolve the humanitarian crisis, he says. Spencer is just one of many voices in the public health realm pushing for more international ...

Prioritize Goals of Older Patients With Multimorbidities

May 5th, 2021 - When caring for older adults with multiple chronic conditions, prioritizing patient goals is more effective and efficient than trying to address each condition in isolation, said Mary Tinetti, MD, Gladys Phillips Crofoot Professor of Medicine and Public Health and chief of geriatrics at Yale University, New Haven, Conn. During a virtual presentation at the American College of Physicians annual ...

Vaping Linked to Visual Impairment

May 5th, 2021 - People who use e-cigarettes have a high rate of visual impairment, researchers say, and that association is independent of and in addition to traditional cigarette use. The statistical correlation doesn't prove that vaping causes visual impairment. But it parallels earlier studies that link tobacco smoking to visual impairment, and vaping to lung damage. And it raises new questions about whethe...

Reduced Kidney Function Tied to Increased Dementia Risk

May 5th, 2021 - NEW YORK (Reuters Health) - Older adults with reduced kidney function may be an increased risk of developing dementia, according to a large population-based study from Sweden. "Even a mild reduction in kidney function has been linked to an increased risk of cardiovascular disease and infections, and there is growing evidence of a relationship between the kidneys and the brain," Dr. Hong Xu of t...

Preventing Endoscopist Injuries Starts With Ergonomics

May 5th, 2021 - Endoscopists are at high risk of musculoskeletal issues, and a multifaceted strategy is needed to reduce rates of injury, including better body posture and endoscopic suite layout, according to leading experts. Latha Alaparthi, MD, director of committee operations at Gastroenterology Center of Connecticut, Hamden, and assistant clinical professor at Yale University, New Haven, Conn. , noted tha...

No Extra Drop in AF Burden from Postablation Weight-Loss Program: SORT-AF

May 5th, 2021 - Obesity is well known to promote atrial fibrillation (AF), and catheter ablation can dramatically cut back on AF prevalence. But assigning patients to a structured obesity-reduction program after AF ablation may not enhance the treatment's effect on AF burden, a novel randomized trial suggests. Of 133 patients with symptomatic persistent or paroxysmal AF with a body mass index (BMI) in the 30 t...

COVID Restrictions Tough for Individuals With Autism and Their Caregivers

May 5th, 2021 - NEW YORK (Reuters Health) - COVID-19 restrictions greatly impacted young people with neurodevelopmental disorders and their caregivers, according to results of a large survey released at the International Society for Autism Research (INSAR) annual meeting. Overall, the survey results highlight the fact that COVID-19 restrictions "disrupted access to medical and therapeutic services and created ...

Pediatric Cancer Survivors at Risk for Opioid Misuse

May 5th, 2021 - Survivors of childhood cancers are at increased risk for prescription opioid misuse compared with their peers, a review of a claims database revealed. Among more than 8,000 patients age 21 or younger who had completed treatment for hematologic, central nervous system, bone, or gonadal cancers, survivors were significantly more likely than were their peers to have an opioid prescription, longer ...

CVST With AZ COVID Vaccine: 1 in 40,000 'More Reliable' Estimate

May 5th, 2021 - Editor's note: Find the latest COVID-19 news and guidance in Medscape's Coronavirus Resource Center. A new study that systematically monitored rates of vascular and thromboembolic events in people receiving the AstraZeneca COVID-19 vaccine has found it to be associated with a rate of cerebral venous sinus thrombosis (CVST) of 1 in 40,000. "Early on, we thought CVST was a very rare occurrence — ...

Going Viral: Social Media May Be Increasing Cases of New-Onset Tics

May 5th, 2021 - This transcript has been edited for clarity. Kathrin LaFaver, MD: Hello. I'm Dr Kathrin LaFaver, a movement disorders specialist at Northwestern University here in Chicago. It is my great pleasure today to interview Dr Tamara Pringsheim on the topic of acute-onset explosive tic-like behaviors. Dr Pringsheim is an associate professor in the Department of Clinical Neurosciences, Psychiatry, Pedia...

Suicide Risk Prediction Tools Fail Racialized Patients

May 5th, 2021 - Current models used to predict suicide risk fall short for racialized populations including Black, Indigenous, and People of Color (BIPOC), new research shows. Investigators developed two suicide prediction models to examine whether these types of tools are accurate in their predictive abilities, or whether they are flawed. Table 2. Area Under the Curve (AUC) Sensitivity for Predication Models ...

Moderna Announces First Data Showing Efficacy of COVID-19 Vaccine Booster in Development

May 5th, 2021 - Find the latest COVID-19 news and guidance in Medscape's  Coronavirus Resource Center. The Moderna SARS-CoV-2 vaccine booster developed specifically with variant B. 1

Majority of Parents Will Wait on Kids' COVID Vaccine

May 5th, 2021 - Editor's note: Find the latest COVID-19 news and guidance in Medscape's Coronavirus Resource Center. Three-quarters of parents don't plan to vaccinate their kids against COVID-19 when the FDA gives the go-ahead for younger children, according to a new survey. Many said they'd wait a few months, but a full third said they don't plan to vaccinate their kids at all Gretchen Schaeffer's 14-year-old...

COVID-Related Mental Illness Rises, Capacity to Treat Falls

May 5th, 2021 - Editor's note: Find the latest COVID-19 news and guidance in Medscape's Coronavirus Resource Center. During the COVID-19 pandemic, the percentage of Americans reporting symptoms of mental illness has increased, and the capacity to treat these disorders has decreased, a new report from the Government Accountability Office (GAO) shows. The GAO report did not explain why so many organizations that...