About 542,653 results

Gaps in ulcerative colitis care expectations, perceptions
Thomas R. Collins

Jun 24th, 2022 - Gaps in priorities and perceptions about managing disease exist between physicians and patients with ulcerative colitis (UC), according to survey findings recently published in Therapeutic Advances in Gastroenterology. The results – which come from the Ulcerative Colitis Narrative Survey from Japan – point to the ongoing need to foster a good relationship between physicians and patients, even a.

Type 2 Diabetes and COVID-19

Jun 24th, 2022 - How much does the risk of new-onset type 2 diabetes (T2D) increase in patients who have had a mild SARS-CoV-2 (COVID-19) infection? Dr. Jain: We are now finding many associations between COVID-19 and T2D.

Study links sleep and objective, subjective cognition
Richard Mark Kirkner

Jun 23rd, 2022 - CHARLOTTE, N. C.

Tofersen linked to slow, positive effects in ALS
Kate Johnson

Jun 23rd, 2022 - An open-label extension of Biogen’s phase 3 VALOR study shows statistically significant benefits for the company’s novel antisense oligonucleotide (ASO), tofersen, in patients with amyotrophic lateral sclerosis (ALS) caused by superoxide dismutase 1 (SOD1) gene mutations. The 1-year results, presented at the European Network for the Cure of Amyotrophic Lateral Sclerosis (ENCALS) 2022 meeting, s.

Autoimmune disorder drugs top list of meds linked to headache
Randy Dotinga

Jun 23rd, 2022 - DENVER – Monoclonal antibodies, antivirals, immunomodulators, and pulmonary arterial vasodilators top the list of drugs that were most frequently implicated as causes of headaches in a federal side effect database that anyone can contribute to, according to a new study presented at the annual meeting of the American Headache Society. “Surprising findings included the significant number of immun.

SBRT plus TACE better than monotherapy in HCC with portal vein tumor thrombus

Jun 23rd, 2022 - Key clinical point: Stereotactic body radiotherapy (SBRT) plus transcatheter arterial chemoembolization (TACE) may be safe and more effective than either of the procedures alone (monotherapy) for treating inoperable hepatocellular carcinoma (HCC) with portal vein tumor thrombus (PVTT). Major finding: SBRT plus TACE vs.

NAFLD significantly increases the risk for HCC

Jun 23rd, 2022 - Key clinical point: Nonalcoholic fatty liver disease (NAFLD) is independently associated with an increased risk for hepatocellular carcinoma (HCC). Major finding: NAFLD significantly increased the risk for HCC (hazard ratio [HR] 1.

Similar prognosis in pregnant vs. nonpregnant BC patients receiving chemotherapy

Jun 23rd, 2022 - Key clinical point: Patients with breast cancer (BC) treated with standard chemotherapy during pregnancy show comparable prognosis to young nonpregnant patients with BC, supporting chemotherapy initiation in pregnant women with BC as indicated. Major finding: Median follow-up was 66.

Artificial intelligence: The Netflix of cancer treatment
Lucas Franki, Richard Franki et. al.

Jun 23rd, 2022 - Chemotherapy, now streaming at just $15. 99 a month! It’s a lazy Sunday and you flip on Netflix, looking for something new to watch.

Metformin disappoints in high-risk operable breast cancer

Jun 23rd, 2022 - Key clinical point: In patients with high-risk operable breast cancer (BC) and without diabetes, adding metformin to standard BC treatment did not improve the invasive disease-free survival (iDFS) rate, regardless of estrogen receptor/progesterone receptor (ER/PgR) status. Major finding: The incidence rates of iDFS events were similar between the metformin and placebo groups in patients with ER.

Advanced TNBC: Camrelizumab + apatinib and eribulin shows promise in heavily pretreated patients

Jun 23rd, 2022 - Key clinical point: The combination of camrelizumab, apatinib, and eribulin demonstrated a favorable efficacy and a manageable safety profile in patients with heavily pretreated advanced triple negative breast cancer (TNBC). Major finding: The objective response rate (ORR), disease control rate, and median progression-free survival in the overall cohort were 37.

Atopic dermatitis: Real-world analysis of characteristics of patients initiating dupilumab

Jun 23rd, 2022 - Key clinical point: In a real-world setting, patients initiating dupilumab reported longstanding moderate-to-severe atopic dermatitis (AD) with frequent type 2 comorbidities and poor quality of life (QoL). Major finding: Patients reported experiencing AD for a median duration of 17 years, with 93.

Provider recommendation key to boosting teen HPV vaccines
Diana Swift

Jun 23rd, 2022 - Human papilloma virus (HPV) vaccination coverage of at least one dose significantly increased in U. S.

Addressing the impact of skin disorders in children and young people

Jun 23rd, 2022 - For children and young people, skin disorders can have a devastating impact on physical and mental wellbeing, yet effective treatments are few and far between. That’s why the Medical Research Foundation is pledging £1 million of new funding to help advance scientific understanding of these conditions, which could ultimately lead to improved support and treatment for children and young people li...

Increase in leptin levels in preeclampsia prompts cardiovascular cascade that puts mother and baby at risk

Jun 23rd, 2022 - AUGUSTA, Ga. (June 23, 2022) – Before a baby is ever born, critical supply chain problems with nutrition and oxygen can result in premature birth or even death and increase the child and mother’s lifelong risk of cardiovascular disease. Scientists have found that a midgestation increase in the hormone leptin, which most of us associate with appetite suppression, produces problematic blood vesse...

Diagnosis of PAH: What Are the Causes and Why Does It Take So Long?

Jun 23rd, 2022 - This transcript has been edited for clarity. Vallerie McLaughlin, MD: Hello. I'm Dr Vallerie McLaughlin, the Kim A. Eagle Endowed Professor of Cardiovascular Medicine at the University of Michigan in Ann Arbor. I would like to welcome you to today's Medscape InDiscussion series on pulmonary arterial hypertension (PAH). This is episode 2: diagnosis of PAH. What are the challenges and why does it...

Classifications and Causes of Pulmonary Hypertension

Jun 23rd, 2022 - This transcript has been edited for clarity. Vallerie McLaughlin, MD: Hello, and welcome to this podcast series. I'm Dr Vallerie McLaughlin, the Kim A. Eagle Endowed Professor of Cardiovascular Medicine and director of the Pulmonary Hypertension Program at the University of Michigan Medical School in Ann Arbor, Michigan. I'm joined today by my dear friend and colleague, Dr Raymond Benza from Oh...

A Scrotal Rash Lasting Months in a Man With Genital Edema

Jun 23rd, 2022 - Editor's Note: The Case Challenge series includes difficult-to-diagnose conditions, some of which are not frequently encountered by most clinicians but are nonetheless important to accurately recognize. Test your diagnostic and treatment skills using the following patient scenario and corresponding questions. If you have a case you would like to suggest for a future Case Challenge, please conta...

Leaks After Percutaneous Left Atrial Appendage Occlusion and Stroke Risk

Jun 23rd, 2022 - Christopher V. DeSimone, MD, PhD: Hello, and welcome back to the Mayo Clinic–Medscape video series. I'm Dr Christopher DeSimone, cardiologist and director of cardiovascular marketing here at Mayo Clinic. Today we're going to be discussing leaks after left atrial appendage closure and how this can increase stroke risk. I'm joined by my colleague, Dr Mohamad Alkhouli, professor of interventional ...

ADA-EASD: More Holistic Approach Needed for Hyperglycemia Management

Jun 23rd, 2022 - This transcript has been edited for clarity. In the 2022 Management of Hyperglycemia consensus statement from the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD), the focus has shifted. Regarding the management of hyperglycemia, we feel a more holistic approach is needed. What we mean by that is a four-part simultaneous attention on glycemic man...