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About 7,555 results

Tofacitinib Postmarketing Data Shed Light on JAK Inhibitor Risks
https://www.medscape.com/viewarticle/963183

Nov 17th, 2021 - Additional analyses of a postmarketing trial that was required after the Food and Drug Administration's approval of the Janus kinase inhibitor tofacitinib (Xeljanz, Xeljanz XR) has identified characteristics of older patients with rheumatoid arthritis with at least one cardiovascular risk factor who may be at higher risk for major adverse cardiovascular events (MACE) when taking the drug. Resul...

Anti-Inflammatory Therapy Linked to Reduction of CV Events
https://www.medscape.com/viewarticle/962932

Nov 15th, 2021 - This is a summary of a preprint research study by Zhi-Lu Wang and colleagues from The First Hospital of Lanzhou University on Research Square, provided to you by Medscape. This study has not yet been peer-reviewed. The full text of the study can be found on Researchsquare.com. Key Takeaway Patients with coronary artery disease (CAD) who received anti-inflammatory therapy had significantly lower...

Mental Stress-Induced CV Events; Telling Retina Scans; Bedtime and Heart Health
https://www.medpagetoday.com/cardiology/prevention/95549

Nov 9th, 2021 - Theories abound regarding the mechanism behind the link between mRNA vaccines and myocarditis. (Wall Street Journal) Registry data show that COVID-19 patients with ischemic heart disease were not at a disadvantage in survival, whereas those with heart failure experienced excess in-hospital deaths. (European Heart Journal) A larger study confirmed the link between mental stress-induced myocardia...

Treating Young Adults With High LDL May Be Cost-Effective
https://www.medscape.com/viewarticle/962514

Nov 8th, 2021 - Treating elevated low-density lipoprotein cholesterol (LDL-C) in adults younger than 40 with statins is highly cost-effective in men, and intermediately cost-effective in women, a new report suggests. In a simulated model based on data from the US National Health and Nutrition Examination Survey (NHANES), lipid lowering with statins or lifestyle interventions in this age group would prevent or ...

More Than Half of People Living With HIV Have Coronary Plaque
https://www.medscape.com/viewarticle/962421

Nov 5th, 2021 - More than half of people living with HIV and suppressed viral loads nonetheless had imaging-confirmed coronary artery disease — and despite longtime use of HIV drugs that have been associated with cardiovascular trouble, none of those drugs were implicated in disease risk in this study. "Traditional risk factors and duration of HIV infection was associated with severe coronary artery disease," ...

A CAC Score of 0 Is Not a Clean Bill of Heart Health
https://www.medpagetoday.com/cardiology/prevention/95287

Oct 27th, 2021 - A zero coronary artery calcium (CAC) score didn't necessarily mean zero obstructive coronary artery disease (CAD) in symptomatic patients, a Danish group found. Among those with a CAC score of zero, 3% of adults younger than 40 had obstructive CAD compared with 8% of those 70 and older in the large Western Denmark Heart Registry of 23,759 symptomatic patients, reported Martin Bødtker Mortensen,...

Cataracts and Vascular Health; Risky Stimulant Use; CEC Adjudication Flaws
https://www.medpagetoday.com/cardiology/prevention/95267

Oct 26th, 2021 - Does cataract surgery predict vascular and all-cause mortality a decade later? (British Journal of Ophthalmology) The "5 As" -- assess, advise, agree, assist, and arrange -- were highlighted in the American Heart Association's statements on how to promote healthy lifestyles to patients of all cardiovascular risk categories and special populations. (Circulation) CDC found that the proportion of ...

Familial Hypercholesterolemia — Hiding in Plain Sight
https://www.medscape.com/viewarticle/958283

Oct 21st, 2021 - This transcript has been edited for clarity. Laurence Sperling, MD: Welcome to the Medscape InDiscussion podcast series on dyslipidemia. This is the first of six episodes. To launch this series today, we will focus on an extremely important topic: living with hypercholesterolemia and listening for clues of genetic risk. This topic is central to this series. First, a case presentation. A 38-year...

FDA Looks Closer at Myocarditis; Cognition and DOACs; Silver Lining of Lockdowns?
https://www.medpagetoday.com/cardiology/prevention/95128

Oct 19th, 2021 - The American Heart Association warns that progress is slowing in national care for ST-segment elevation myocardial infarction. (Circulation) FDA's internal deliberations on myocarditis risk will delay its decision on authorizing the Moderna COVID-19 vaccine for adolescents. (Wall Street Journal) Takotsubo syndrome disproportionately affects older women in the U.S., though its incidence is risin...

Earlier-Life CAC Scans; Omega-3s and Afib; RV vs LV Abnormalities in COVID
https://www.medpagetoday.com/cardiology/prevention/94991

Oct 12th, 2021 - Should some individuals at risk of atherosclerotic cardiovascular disease start getting coronary artery calcium scans in their mid-to-late 30s? (Journal of the American College of Cardiology) IV thrombolytics may be safe for stroke patients with unruptured intracranial aneurysms, a single-center study found. (Neurology) Major thromboembolism and death were less likely when hospitalized COVID-19...

High-Dose Omega-3s Tied to Higher Risk for Atrial Fibrillation
https://www.medscape.com/viewarticle/960606

Oct 11th, 2021 - Taking high-doses of marine omega-3 fatty acids, more than 1 gram daily, may raise the risk for atrial fibrillation (AF), according to a meta-analysis of relevant research.  However, the risk of developing AF appears to be "relatively small" for those taking 1 gram or less of fish oil per day, Christine Albert, MD, chair of the  Department of Cardiology at the Smidt Heart Institute at Cedars-Si...

High-Dose Omega-3s Tied to Higher Risk for Atrial Fibrillation
https://www.medscape.com/viewarticle/960606?src=

Oct 11th, 2021 - Taking high-doses of marine omega-3 fatty acids, more than 1 gram daily, may raise the risk for atrial fibrillation (AF), according to a meta-analysis of relevant research.  However, the risk of developing AF appears to be "relatively small" for those taking 1 gram or less of fish oil per day, Christine Albert, MD, chair of the  Department of Cardiology at the Smidt Heart Institute at Cedars-Si...

Longer Exposure to Elevated LDL Tied to Higher CHD Risk
https://www.medscape.com/viewarticle/960460

Oct 7th, 2021 - Higher exposure to LDL cholesterol (LDL-C) during young adulthood and middle age is associated with a significantly higher risk of coronary heart disease (CHD), regardless of midlife lipid levels, new research suggests. Investigators analyzed pooled data from four prospective studies, encompassing over 18,000 participants with an average age of 56 years, to assess a potential association betwee...

Vaping Still at Large; GDMT Down Amid COVID; Novel Avenue for Cholesterol Lowering
https://www.medpagetoday.com/cardiology/prevention/94866

Oct 5th, 2021 - The American Heart Association decried the regulatory loopholes that allow flavored tobacco products to stay on the market and be used by young people. The shift to remote heart failure care during the pandemic was marked by less diagnostic testing and reduced prescription of guideline-directed medical therapies. (Circulation: Heart Failure) COVID-19 patients given antiplatelet therapy in the h...

Extracranial Cerebrovascular Disease Clinical Practice Guidelines (SVS, 2021)
https://www.medscape.com/viewarticle/960036

Oct 1st, 2021 - Guidelines for the management of extracranial cerebrovascular disease were published in June 2021 by the Society for Vascular Surgery (SVS) in Journal of Vascular Surgery.[1] Carotid endarterectomy (CEA) is recommended as first-line treatment for symptomatic low-risk surgical patients with stenosis of 50% to 99% and asymptomatic patients with stenosis of 70% to 99%. Carotid revascularization is...

Oct 1, 2021 This Week in Cardiology Podcast
https://www.medscape.com/viewarticle/960027

Oct 1st, 2021 - Please note that the text below is not a full transcript and has not been copyedited. For more insight and commentary on these stories, subscribe to the This Week in Cardiology podcast on Apple Podcasts, Spotify, or your preferred podcast provider. In This Week’s Podcast For the week ending October 1, 2021, John Mandrola, MD comments on the following news and features stories. CAC and Exercise ...

Inactive Lifestyles Lead to More Frequent, Severe Hot Flashes: Study
https://www.medscape.com/viewarticle/960078

Sep 30th, 2021 - In the age of COVID-19, it's super easy to find yourself sitting or lying down for a good chunk of the day, also known as sedentary behavior. Working from home, traveling less, and opting for DoorDash and Hulu over a date night at your favorite restaurant all keep us inside the house, sometimes with limited space. Not getting enough movement can damage your health and cause many preventable hea...

FDA Probes LAAO; Dairy Fat's Heart Benefit; Repatha OK'd for Pediatric HeFH
https://www.medpagetoday.com/cardiology/prevention/94751

Sep 28th, 2021 - In response to a study published in August, FDA is investigating whether women really have worse outcomes after Watchman left atrial appendage occlusion (LAAO) than men. Shorter intervals between measurements: a way to slice a minute off standard protocol for automated office-based blood pressure evaluation. (Hypertension) Transcatheter aortic valve replacement (TAVR) performed well as an alter...

Silent Coronary Atherosclerosis Prevalent on CT in Middle Age
https://www.medscape.com/viewarticle/959907

Sep 28th, 2021 - Four in 10 middle-aged individuals without a history of heart disease have silent coronary atherosclerosis and 1 in 20 have significant stenosis on coronary CT angiography (CCTA), Swedish researchers report. "What's important is that we actually looked at the atherosclerosis of the vessel wall with angiography and now have data on the extent and the severity of atherosclerosis in the general po...

A Way to Funnel Patients From ER Discharge to Further Coronary Testing
https://www.medpagetoday.com/cardiology/prevention/94727

Sep 27th, 2021 - With rapid troponin testing in emergency rooms, people who had acute coronary syndrome ruled out could still learn if they had any heart disease that may be confirmed with outpatient testing, the PRECISE-CTCA study showed. Among 250 people discharged with "normal" high-sensitivity cardiac troponin I (hs-cTnI), those with intermediate hs-cTnI concentrations (between 5 ng/L and the sex-specific 9...