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About 24,003 results

CRC Screening: Blood Test Accuracy Compared to Colonoscopy
https://www.medscape.com/viewarticle/974402

May 21st, 2022 - The first prospective study to evaluate the accuracy of a blood test for people being screened for colorectal cancer (CRC) revealed a high sensitivity and specificity. At 90% specificity, the blood assay (Guardant Health) was 100% sensitive for detecting CRC. At 95% specificity, sensitivity was 88%. The blood assay detects circulating tumor DNA from cancer in the bloodstream, which is then anal...

AYA Leukemia Survivors: 'Cure Is Not Enough'
https://www.medscape.com/viewarticle/974337

May 20th, 2022 - Although adolescents and young adults (AYAs) who survive leukemia are living much longer than ever before, their life spans are still shorter than those of the general population, a new study concludes. The study found that the 10-year survival of AYA leukemia survivors was approximately 10% lower than that of the age-adjusted US general population at large. These differences persisted for up t...

Shift to HPV Testing Will Require Public Education
https://www.medscape.com/viewarticle/974261

May 19th, 2022 - The shift from Papanicolaou (Pap) cytology to direct testing for the human papillomavirus (HPV) represents a major advance in cervical cancer screening. Nevertheless, some experts like Emily Delpero, MD, of Mount Sinai Hospital in Toronto, Canada, expect significant initial pushback from patients and physicians alike. Others like Marc Steben, MD, co-director of HPV Global Action, and professor ...

New Image-Based Risk Model Helps Predict Future Breast Cancers
https://www.medscape.com/viewarticle/974266

May 19th, 2022 - Researchers have created and validated a risk model based on digital breast tomosynthesis (DBT) images that can predict a woman's chance of developing breast cancer within a year of a negative or benign mammography screening exam. This model could potentially lead to earlier detection and improved prognosis. "The DBT risk model is fully automated and provides the clinician with a risk category ...

Some Smokers Don't Get Lung Cancer; Genetics Might Explain It
https://www.medscape.com/viewarticle/974299

May 19th, 2022 - Some smokers might not get lung cancer because of their DNA, researchers report in a new study. These people have genes that help limit mutations, or changes, to DNA that would turn cells malignant and make them grow into tumors, the researchers say. Scientists have long suspected that smoking leads to lung cancer by triggering DNA mutations in healthy cells. But it was hard for them to identif...

What Is the Optimal Treatment for Multifocal Intrahepatic Cholangiocarcinoma?
https://www.medscape.com/viewarticle/974146

May 18th, 2022 - NEW YORK (Reuters Health) - In patients with multifocal intrahepatic cholangiocarcinoma (iCCA), hepatic arterial infusion pump (HAIP) floxuridine chemotherapy may be an effective alternative to surgery, a cohort study suggests. "We believe that these findings are practice-changing," Stijn Franssen and Dr. Bas Groot Koerkamp, both of Erasmus MC Cancer Institute in Rotterdam, told Reuters Health ...

Liquid Biopsy Predicts Resistance to Neoadjuvant Therapy in Esophageal Cancer
https://www.medscape.com/viewarticle/974120

May 18th, 2022 - NEW YORK (Reuters Health) - Researchers have developed and validated a liquid biopsy assay that can predict response to neoadjuvant therapy (NAT) in patients with esophageal squamous-cell carcinoma (ESCC), which may lead to more-personalized treatment decisions. ESCC is one of the most aggressive and lethal subtypes of esophageal cancer and response to NAT is mixed. Predicting NAT resistance is...

Improved Cancer Survival in States with ACA Medicaid Expansion
https://www.medscape.com/viewarticle/974180

May 18th, 2022 - In states that adopted Medicaid expansion following the implementation of the Affordable Care Act (ACA), patients with cancer have improved 2-year overall survival rates when compared with patients in states that did not adopt the expansion. The finding comes from an American Cancer Society study, published online today in the Journal of the National Cancer Institute, of more than 2 million pat...

Sexual Minorities Less Likely to Receive Pap Screening
https://www.medscape.com/viewarticle/974028

May 17th, 2022 - NEW YORK (Reuters Health) - Sexual minorities who have a cervix are less likely than heterosexual women to be screened for cervical cancer, a new study suggest. An analysis of data from more than 18,000 people who were assigned female sex at birth and who participated in a national health survey revealed that sexual minorities (SM) were half as likely as heterosexual women to ever undergo Pap s...

Risk Factors for COVID Death Studied in U.K. Arthritis Patients
https://www.medscape.com/viewarticle/974101

May 17th, 2022 - Being identified as someone that was advised to stay at home and shield, or keep away from face-to-face interactions with others, during the COVID-19 pandemic was indicative of an increased risk for dying from COVID-19 within 28 days of infection, a U.K. study of inflammatory arthritis patients versus the general population suggests. In fact, shielding status was the highest ranked of all the r...

As Red Cross Moves to Pricey Blood Treatment Method, Hospitals Call for More Choice
https://www.medscape.com/viewarticle/974128

May 17th, 2022 - Americans generally don't spend much time thinking about the nation's blood supply. That's mainly because the collection and distribution system is safe and efficient. But there's a new behind-the-scenes challenge, according to some hospital officials, who fear a change in how blood platelets are handled will sharply increase the cost — and, in some cases, the number of transfusions needed — to...

Mastectomy May Not Be Necessary for Young Breast Cancer Patients
https://www.medscape.com/viewarticle/974134

May 17th, 2022 - Mastectomies among younger women with nonmetastatic invasive breast cancer may not always be necessary, according to a new study that shows survival outcomes are similar to those of women who had a lumpectomy. The results come as an increasing number of women under 40 choose mastectomy. "A lot of times, there's this assumption that removal of the entire breast is going to prevent cancer from re...

Alarming Increase in Esophageal Cancer in Middle-Aged Adults
https://www.medscape.com/viewarticle/974049

May 16th, 2022 - An alarming increase in both esophageal cancer (EC) and the primary precursor lesion for esophageal adenocarcinoma known as Barrett's esophagus (BE) has been observed among middle-aged adults over the past 5 years, and it's not due to better or more frequent screening, warn the authors of a new study from Florida. "We found that the [prevalence of] esophageal cancer and Barrett's esophagus may ...

Jury Is In? Survival Benefit With Lap Surgery for Rectal Cancer
https://www.medscape.com/viewarticle/974058

May 16th, 2022 - Laparoscopic surgery can improve long-term overall survival (OS) compared with open surgery for patients with rectal cancer, according to findings from a large meta-analysis. The estimated 5-year OS rate for patients who underwent laparoscopic surgery was 76.2%, vs 72.7% for those who had open surgery. "The survival benefit of laparoscopic surgery is encouraging and supports the routine use of ...

Cancer Patients Unaware of Their Increased Thrombosis Risk
https://www.medscape.com/viewarticle/974066

May 16th, 2022 - More than 70% of cancer patients do not know that they are at greater risk of deep vein thrombosis (DVT) than the general population. It is up to their physician to discuss this with them. This link is explained by the authors of an article in Cancer Treatment and Research Communications that reports results of a survey carried out by the European Cancer Patient Coalition (ECPC). "The aim of th...

HPV Strains Covered by the Vaccine Have Declined Greatly in the US
https://www.medscape.com/viewarticle/974084

May 16th, 2022 - Twelve years after the human papillomavirus (HPV) vaccination program was introduced in the United States, the overall prevalence of cancer-causing HPV strains covered by the vaccine dropped by 85% among females — 90% among vaccinated females and 74% among unvaccinated females — a strong sign of herd immunity, a new analysis of a nationally representative database is showing. "HPV vaccination i...

Rapid Review Quiz: Carcinogens
https://www.medscape.com/viewarticle/973380

May 16th, 2022 - The US National Institute of Environmental Health Sciences and National Toxicology Program has cited the identification of carcinogens as a key step in cancer prevention and the improvement of public health, and this is in line with the view of the World Health Organization. Review the latest research into physical, chemical, and biological carcinogens, including newly recognized substances, wi...

How to Weed Out False Positives on Breast MRIs
https://www.medscape.com/viewarticle/974016

May 16th, 2022 - The study was published on researchsquare.com as a preprint and has not yet been peer reviewed. Key Takeaway On breast MRIs, oval/round masses, masses with T2 hyperintense enhancement, and non-mass lesions with homogeneous enhancement patterns are unlikely to be malignant and are more likely to yield false positive results. Why This Matters Use of breast MRI as a screening tool is limited by th...

Most Men With Low-Risk Prostate Tumors Now Forgoing Treatment
https://www.medscape.com/viewarticle/974009

May 15th, 2022 - The number of men with prostate cancer who opted for active surveillance (AS)   doubled nationally between 2014 and 2021, according to experts who say the dramatic increase reflects a growing understanding among both researchers and patients that low-grade prostate tumors can be safely watched for years without requiring treatment. Dr Matthew Cooperberg Roughly 60% of men eligible for AS chose ...

Hormonal Therapy Produces Best Cryptorchidism Outcomes
https://www.medscape.com/viewarticle/973940

May 13th, 2022 - Researchers published the study covered in this summary on researchsquare.com as a preprint that has not yet been peer reviewed. Key Takeaways The results suggested that early prolonged hormonal therapy is advisable in all patients with cryptorchidism to increase the speed of testicular descent to the scrotum achieved by surgery, and thereby maintain adequate sperm quality in adulthood. Why Thi...