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About 18,865 results

Patent Foramen Ovale Clinical Practice Guidelines (SCAI, 2022)
https://www.medscape.com/viewarticle/974545

May 27th, 2022 - Clinical practice guidelines on the management of patent foramen ovale (PFO) from the Society for Cardiovascular Angiography and Interventions (SCAI) were published in May 2022 in  JSCAI.[1] In patients aged 18-60 years who have had a PFO-related stroke, PFO closure is strongly recommended instead of antiplatelet therapy alone. For patients aged 60 years and older with a history of PFO-related ...

Harnessing the immune system to treat traumatic brain injury in mice
https://www.eurekalert.org/news-releases/953857

May 26th, 2022 - A therapeutic method for harnessing the body’s immune system to protect against brain damage is published today by researchers from the Babraham Institute’s Immunology research programme. The collaboration between Professor Adrian Liston (Babraham Institute) and Professor Matthew Holt (VIB and KU Leuven; i3S-University of Porto) has produced a targeted delivery system for boosting the numbers o...

Could Neutrophil Counts Predict Cardiovascular Outcomes?
https://www.medscape.com/viewarticle/974588

May 25th, 2022 - MILAN — Increases in neutrophil counts appear to be causally associated with incident coronary artery disease (CAD) and myocardial infarction (MI), suggests a novel analysis that combined observational and genetic data. The study initially confirmed the association between increased neutrophil counts and coronary artery disease, ischemic cerebrovascular disease, ischemic stroke, and vascular de...

Vascular Risk Factors for Dementia Vary With Age
https://www.medscape.com/viewarticle/974601

May 25th, 2022 - Vascular risk factors for dementia vary with age, new research suggests. New data from the Framingham Heart Study show that high systolic blood pressure (SBP) and diabetes are the most important vascular risk factors for increased 10-year incident dementia at age 55, whereas heart disease was identified as a more important risk factor for dementia at age 65. These findings, researchers note, hi...

Better Biopsies? High-Speed 3D Cameras Could Be the Future
https://www.medscape.com/viewarticle/974541

May 24th, 2022 - Biopsies haven't changed much in the more than 100 years they've been in medical use: Tissue (a cluster of cells) is cut from the body, embedded into a block, thinly sliced, mounted on a slide, and stained with dye. A pathologist then analyzes the sample with a microscope. Results come back in 2 to 10 days while the patient and their family nervously wait.  Engineers at Columbia University are ...

High social vulnerability predicts worse long-term outcomes after traumatic injury
https://www.eurekalert.org/news-releases/953769

May 24th, 2022 - Traumatic injuries — such as physical injuries resulting from a car accident, fall, gunshot or stabbing — are one of the most common causes of impairment and disability worldwide. A team of investigators led by Juan P. Herrera-Escobar, MD, MPH, of the Brigham’s Center for Surgery and Public Health, found that living in an area with higher social vulnerability is strongly associated with worse m...

Thrombolysis Safe in Stroke Patients on Oral Anticoagulants
https://www.medscape.com/viewarticle/974407

May 23rd, 2022 - Intravenous thrombolysis (IVT) for acute stroke appears safe for patients who have recently received direct oral anticoagulant (DOAC) therapy, a new observational study suggests, prompting researchers to ask whether guidelines that restrict its use should be updated. Researchers found that DOAC users were significantly less likely to develop symptomatic intracerebral hemorrhage (sICH) after IVT...

Fewer Teens Giving Birth, but Cases Are More Complex
https://www.medscape.com/viewarticle/974457

May 23rd, 2022 - Debra Katz, CNM, has noticed a shift in the number of teenagers coming to the teen obstetrics program at St. Joseph's Medical Center in Paterson, New Jersey. A decade ago, about 30 adolescents gave birth in a given month; now, that figure is closer to 20, said Katz, chief of the nurse midwifery service at the center. Katz's observations mirror a national trend: The rate of teen births is fallin...

SGLT-2 inhibitors as First-Line Therapy in Type 2 Diabetes?
https://www.medscape.com/viewarticle/974463

May 23rd, 2022 - Use of sodium–glucose cotransporter-2 (SGLT-2) inhibitors rather than metformin as first-line treatment for type 2 diabetes appears to cut the risk for heart failure hospitalization but not myocardial infarction (MI), stroke, or all-cause mortality, a new analysis of real-world data suggests. Safety findings were similar, except for the fact that genital infections were more common with SGLT-2 ...

Hearing, Vision Loss Combo a Colossal Risk for Cognitive Decline
https://www.medscape.com/viewarticle/974431

May 23rd, 2022 - The combination of hearing loss and vision loss is linked to an eightfold increased risk of cognitive impairment, new research shows. Investigators analyzed data on more than 5 million US seniors. Adjusted results show that participants with hearing impairment alone had more than twice the odds of also having cognitive impairment, while those with vision impairment alone had more than triple th...

SCAI Issues Guidelines for PFO Management, Makes Case for Expansion
https://www.medscape.com/viewarticle/974398

May 20th, 2022 - The first-ever guidelines for interventional cardiologists using percutaneous patent foramen ovale closure recommend expanding the use of the procedure beyond the Food and Drug Administration-approved indication following PFO-associated ischemic stroke, adding clarification about the use of PFO with anticoagulation and hedging against abuse and overuse of the procedure, said the chair of the gu...

Genomic Risk Score Predicts Intracerebral Hemorrhage Risk
https://www.medscape.com/viewarticle/974319

May 19th, 2022 - The study covered in this summary was published in medRxiv.org as a preprint and has not yet been peer reviewed. Key Takeaway When added to clinical risk factors, a validated genomic risk score can predict the lifetime risk of intracerebral hemorrhage in individuals of European ancestry. Why This Matters Prediction for intracerebral hemorrhage could be improved by adding genomic information to ...

High IL-6 Levels Linked to Carotid Plaque Severity, Progression
https://www.medscape.com/viewarticle/974221

May 18th, 2022 - Increased circulating levels of the cytokine interleukin 6 (IL-6) are associated with carotid plaque severity and progression, contributing to an increased risk of stroke, a new study suggests. The researchers also identified an IL-6 level cutoff that might help clinicians identify patients who could benefit from specific anti-IL-6 treatments. "One of the major conclusions that we could draw fr...

Death Toll on US Roads Rose to Almost 43,000 in 2021
https://www.medscape.com/viewarticle/974212

May 18th, 2022 - Nearly 43,000 people were killed on roads across the U.S. last year, marking the highest number in more than a decade. The death toll jumped 10.5% from 2020 as Americans returned to driving after COVID-19 pandemic quarantine and isolation, according to The Associated Press. The increase represents the largest percentage jump in numbers since the National Highway Traffic Safety Administration be...

Injured women half as likely as men to receive life-saving drug
https://www.eurekalert.org/news-releases/953132

May 18th, 2022 - Injured women are half as likely as men to receive the life-saving drug tranexamic acid (TXA) even though the treatment is equally effective regardless of sex, according to new research in the British Journal of Anaesthesia. The study was conducted by a team from the London School of Hygiene & Tropical Medicine and University Hospitals Plymouth NHS Trust. In this two-part investigation, the tea...

Updated AHA/ASA Guideline Changes Care for Spontaneous Intracerebral Hemorrhage
https://www.medscape.com/viewarticle/974141

May 17th, 2022 - Many strategies widely considered "standard care" for managing spontaneous intracerebral hemorrhage (ICH) are not as effective as previously thought and are no longer recommended in updated guidelines from the American Heart Association (AHA)/American Stroke Association (ASA). Compression stockings, antiseizure medication, and steroid treatment are among the treatments with uncertain effectiven...

Fast Five Quiz: Type 2 Diabetes and Dyslipidemia
https://www.medscape.com/viewarticle/970507

May 16th, 2022 - Type 2 diabetes is a complex metabolic disorder, leading to increased morbidity, mortality, and cost. Dyslipidemia is a common condition coexisting with type 2 diabetes and a clear risk factor for the development of atherosclerotic cardiovascular disease (ASCVD). Primary and secondary prevention of cardiovascular events is essential to the management of type 2 diabetes. Despite the progress in ...

A Surprise and a Mystery: NAFLD in Lean Patients Linked to CVD Risk
https://www.medscape.com/viewarticle/973925

May 13th, 2022 - People with nonalcoholic fatty liver disease (NAFLD) and a lean or healthy body mass index (BMI) are at increased risk for peripheral vascular disease, stroke, and cardiovascular disease, a surprise finding from a new study reveals. "Our team had expected to see that those with a normal BMI would have a lower prevalence of any metabolic or cardiovascular conditions," lead researcher Karn Wijarn...

Recurrent Stroke Risk High in AF, Even With Anticoagulants
https://www.medscape.com/viewarticle/973963

May 13th, 2022 - Patients with atrial fibrillation (AF) who suffer an ischemic stroke while taking direct oral anticoagulants (DOACs) or vitamin K antagonists (VKA) have a dangerously high risk of recurrent stroke and death, a new study shows. Researchers found a mortality rate of just over 12% within 3 months of an ischemic stroke on oral anticoagulation and close to 20% at 1 year, which they said demonstrates...

Stroke in the Young: Cancer in Disguise?
https://www.medscape.com/viewarticle/973973

May 13th, 2022 - Young stroke patients have an increased risk of being diagnosed with a new cancer in the years following their stroke, a new study shows, raising the possibility that the stroke might be the first manifestation of an underlying cancer. The data were presented by Jamie Verhoeven, MD, Radboud University Medical Centre, Netherlands, at the recent European Stroke Organisation Conference 2022. Verho...