Nov 30th, 2022 - The recent approval of teplizumab-mzwv (Tzield, Provention Bio) for the delay of type 1 diabetes by the US Food and Drug Administration is expected to advance efforts to increase screening to cost-effectively identify those at risk for the condition who would be eligible to receive the new treatment. The anti-CD3 monoclonal antibody was approved November 17 as the first disease-modifying therap...

Nov 30th, 2022 - By the time Mira Halker started high school, hardly a day passed that she wasn't either getting a migraine attack or recovering from one. She missed volleyball team practice. She missed classes. She missed social events. And few people understood. After all, she looked healthy. "A lot of times, people think I'm faking it," said Mira, now 16, who lives in Phoenix. Friends called her flaky; her v...

Nov 30th, 2022 - For anyone who doubts that nurses can present themselves as biased, entitled, or deeply disrespectful, they should view this clinician on TikTok. I am ashamed to admit that this nurse is a fellow advanced practice provider, a nurse practitioner (NP) entrusted with the care of patients who seek clinical assistance, empathy, and understanding. In this instance, an expectant mother requested a not...

Nov 29th, 2022 - Welcome to Impact Factor, your weekly dose of commentary on a new medical study. I'm Dr F. Perry Wilson of the Yale School of Medicine. If you've watched this space over the years, you'll know that I'm not the biggest proponent of vitamin D supplementation. My basic gripe is that you've got all these observational studies linking lower levels of vitamin D to everything from dementia to falls to...

Nov 29th, 2022 - CHICAGO ― Higher weight and body mass index (BMI) in preadolescents are linked with poor brain health, new research suggests. Poor brain health has been linked with obesity in adults, but little has been known about the link in children. Simone Kaltenhauser Lead author Simone Kaltenhauser, a postgraduate research fellow in radiology and biomedical imaging at the Yale School of Medicine in New H...

Nov 29th, 2022 - A new collaborative position paper on radiation exposure during pregnancy states that pregnant women can safely work in an ionizing radiation environment if exposure to the fetus does not exceed certain dose thresholds. The position paper aims to "avoid discouraging" women from pursuing careers in interventional cardiology/electrophysiology (IC/EP) and to "dismantle" a barrier that says, "activ...

Nov 29th, 2022 - Reports of respiratory illness continued to rise as the 2022-23 flu season maintained its early surge through mid-November, according to the CDC.  Nationally, 6% of all outpatient visits were because of flu or flu-like illness for the week of Nov. 13-19, up from 5.8% the previous week, the CDC's Influenza Division said in its weekly FluView report. Those figures are the highest recorded in Nove...

Nov 28th, 2022 - "Have you considered tissue donation?" These "five simple words" could have profound impact for pediatric brain cancer research — and for children with brain cancer and their families, according to pediatric neuro-oncologist Vijay Ramaswamy, MD, PhD, at The Hospital for Sick Children in Toronto, Canada. However, families who have lost a child to brain cancer often aren't made aware of the optio...

Nov 28th, 2022 - You may not think that children with attention deficit hyperactivity disorder, or ADHD, have a lot in common with older adults. The kids struggle to sit still and focus on a task. The older adults are great at sitting still, but they often have a hard time following the conversation at a holiday dinner. In both cases, the problem is one of attention. Yes, that's obvious for someone who's been d...

Nov 28th, 2022 - A new study provides some reassurance regarding the cardiovascular safety of medications used to treat attention-deficit/hyperactivity disorder (ADHD). A large meta-analysis showed no statistically significant association between use of stimulant or nonstimulant ADHD medications and any cardiovascular disease (CVD) outcome across age groups. However, a "modest" increase in risk could not be rul...

Nov 28th, 2022 - Pau, France — How can we care for women considering another pregnancy after a stillbirth? At the Infogyn 2022 conference, Christophe Vayssière, MD, PhD, of the Department of Obstetrics and Gynecology at Toulouse University Hospital in France, reported on the need to establish a personalized care plan, with psychologic support if necessary, without having to go through the avalanche of additiona...

Nov 28th, 2022 - 1. There's a lot of flu out there. According to the Centers for Disease Control and Prevention's FluView report, flu activity is elevated across the country, and flu hospitalization rates are the highest we have seen at this time in a decade. Hospitalization rates are highest among adults 65 years or older (18.6 per 100,000), followed by children younger than 5 years (13.6 per 100,000). Indicat...

Nov 23rd, 2022 - Meditation has become a popular practice in the United States over the last decade. It is not limited to adults, but can be learned and practiced by children and teenagers also. Variants are being used in many schools as parts of a social and emotional learning curriculum, and different kinds of mindfulness practices are common parts of psychological treatments. In this month’s column, we will ...

Nov 23rd, 2022 - Brain indicators of motor impairment were distinct among children with autism spectrum disorder (ASD), those with developmental coordination disorder (DCD), and controls, in a new study. Previous research suggests that individuals with ASD overlap in motor impairment with those with DCD. But these two conditions may differ significantly in some areas, as children with ASD tend to show weaker sk...

Nov 22nd, 2022 - Reminder messages sent through electronic health records (EHRs) to patient portals increased rates of scheduling and completion of well-child visits for those overdue for well care, as well as vaccination rates, according to data published today in JAMA Network Open. Anne E. Berset, BA, with general and community pediatrics at Cincinnati Children's Hospital, led a randomized clinical trial cond...

Nov 22nd, 2022 - Primary care physicians are missing key opportunities to discuss with parents the gamut of vaccinations their children should receive, a new survey has found. The COVID-19 pandemic has upended the usual delivery system for childhood vaccines, traditionally the province of pediatricians and other primary care providers, according to researchers at the University of Michigan, Ann Arbor. Some pare...

Nov 22nd, 2022 - This transcript has been edited for clarity. The US Food and Drug Administration (FDA) has just approved teplizumab (Tzield) for the delay of clinical type 1 diabetes in people age 8 years or older who have stage 2 type 1 diabetes. Before I talk about teplizumab, I'm going to talk about the stages of type 1 diabetes that we've learned about over the past decade or so. I think it's important to ...

Nov 22nd, 2022 -   Emergencies happen anywhere, anytime, and sometimes physicians find themselves in situations in which they are the only ones who can help. Is There a Doctor in the House? is a new Medscape series telling these stories. Dr Govani: We were lucky. In 2021, the NFL had chosen some healthcare workers to go to the Super Bowl. We're Rams season ticket holders, and we were chosen. We had an amazing t...

Nov 22nd, 2022 - Schizophrenia is a brain disorder affecting how people think, feel, and perceive. Its primary symptom is psychosis. People with schizophrenia have lower rates of employment, marriage, and independent living compared with others who do not have this disorder. Schizophrenia is a clinical diagnosis. It must be differentiated from other psychiatric and medical illnesses as well as from disorders su...

Nov 22nd, 2022 - Editor's note: Find the latest COVID-19 news and guidance in Medscape's Coronavirus Resource Center. The overall risk of developing myocarditis after COVID-19 vaccination is low, according to a new report from British Columbia, Canada. Because of certain risk factors, however, researchers recommended preferential use of the Pfizer–BioNTech vaccine over the Moderna vaccine for patients aged 18-2...