×
About 38 results

Variants Spur New FDA Guidance on COVID Vaccines, Tests, Drugs
https://www.medscape.com/viewarticle/946266

Feb 21st, 2021 - Editor's note: Find the latest COVID-19 news and guidance in Medscape's  Coronavirus Resource Center. The US Food and Drug Administration (FDA) on Monday updated its October guidance for manufacturers developing COVID-19 vaccines, diagnostics, and treatments in the wake of circulating SARS-CoV-2 variants. The United States is currently facing three main variant threats, according to the Centers...

Visual Interpretation of Tau PET Predicts Cognitive Decline
https://www.medscape.com/viewarticle/946249

Feb 21st, 2021 - A relatively simple and accessible Food and Drug Administration (FDA) approved method of visually classifying flortaucipir PET accurately predicts cognitive deterioration, new research shows. The results from two independent studies consistently showed that patients with a flortaucipir advanced tau pattern had greater mean deterioration across several clinical endpoints within 18 months. Dr Min...

SLN Biopsy for Oral Cancer? French Surgeons Say 'Oui'
https://www.medscape.com/viewarticle/940134

Nov 1st, 2020 - French investigators are suggesting that sentinel lymph node (SLN) biopsy should replace neck lymph node dissection as the new standard for detecting occult metastases in patients with T1-T2N0 oral and oropharyngeal squamous cell carcinoma. In a randomized trial involving 279 patents, oncologic outcomes at 5 years were similar with both techniques, but there was substantially less morbidity wit...

Batten Down the Hatches for Thyroid Storm
https://www.staging.medscape.com/viewarticle/937168

Sep 9th, 2020 - Thyroid storm is a life-threatening endocrine emergency for which, remarkably, there are no definitive diagnostic tests, and the management of which is supported by a startlingly weak evidence base. "What's tricky is there really are no specific biochemical level cutoffs for thyroid storm, and also no unique laboratory abnormalities. So in the end, it's a clinical diagnosis and a clinical judgm...

Vitamin D Tied to Lower Risk for Immunotherapy-Induced Colitis
https://www.medscape.com/viewarticle/933301

Jul 1st, 2020 - Taking vitamin D before starting immune checkpoint inhibitor (ICI) therapy may decrease the risk for treatment-related colitis, say researchers in an article published online on June 22 in the journal Cancer. The study is the first to find a link between pretreatment vitamin D use and decreased risk for ICI colitis, they comment. They caution that the results are preliminary and require confirm...

Fast Five Quiz: Chronic Spontaneous Urticaria
https://reference.medscape.com/viewarticle/920709_5

Jun 14th, 2020 - Both the American Academy of Allergy, Asthma, and Immunology (AAAAI) and the European Academy of Allergy and Clinical Immunology (EAACI)/Global Allergy and Asthma European Network (GA2LEN)/European Dermatology Forum (EDF)/World Allergy Organization (WAO) recommend second-generation antihistamines as the first-line treatment for CSU. Second-generation antihistamines are low-sedation antihistamin...

Longer Survival in Black Men on Newer Prostate Cancer Drugs
https://www.medscape.com/viewarticle/909031

Feb 12th, 2019 - Population-based studies have suggested that, compared with white men, black men are at higher risk of dying from prostate cancer. However, recent findings show that that isn't necessarily the case. In the latest study, survival was longer for African American patients who were treated with the newer hormonal therapies. The findings come from an analysis of chemotherapy-naive patients with meta...

Longer Survival in Black Men on Newer Prostate Cancer Drugs
https://www.staging.medscape.com/viewarticle/909031

Feb 12th, 2019 - Population-based studies have suggested that, compared with white men, black men are at higher risk of dying from prostate cancer. However, recent findings show that that isn't necessarily the case. In the latest study, survival was longer for African American patients who were treated with the newer hormonal therapies. The findings come from an analysis of chemotherapy-naive patients with meta...

Most Drug Treatments Fail to Control Long-term OA Pain
https://www.staging.medscape.com/viewarticle/907032

Dec 26th, 2018 - The first meta-analysis of long-term pharmacologic treatments for knee osteoarthritis (OA) found little evidence that most currently prescribed medications improve pain control or preserve joint structure after 12 months of treatment. There was a small but statistically and clinically significant benefit from prescription-grade glucosamine sulfate. The study, by Dario Gregori, PhD, from the Uni...

Most Drug Treatments Fail to Control Long-term OA Pain
https://www.medscape.com/viewarticle/907032

Dec 26th, 2018 - The first meta-analysis of long-term pharmacologic treatments for knee osteoarthritis (OA) found little evidence that most currently prescribed medications improve pain control or preserve joint structure after 12 months of treatment. There was a small but statistically and clinically significant benefit from prescription-grade glucosamine sulfate. The study, by Dario Gregori, PhD, from the Uni...

Walking Just 4 Hours a Week Linked to Reduced Stroke Severity
https://www.staging.medscape.com/viewarticle/902222

Sep 18th, 2018 - Compared with those who are physically inactive, adults who routinely engaged in light to moderate physical activity prior to a stroke or transient ischemic attack were twice as likely to experience a mild event rather than a moderate or severe one, new research suggests. The retrospective study showed that more than half (52%) of the 925 people in two Swedish stroke registries were physically ...

Walking Just 4 Hours a Week Linked to Reduced Stroke Severity
https://www.medscape.com/viewarticle/902222

Sep 18th, 2018 - Compared with those who are physically inactive, adults who routinely engaged in light to moderate physical activity prior to a stroke or transient ischemic attack were twice as likely to experience a mild event rather than a moderate or severe one, new research suggests. The retrospective study showed that more than half (52%) of the 925 people in two Swedish stroke registries were physically ...

Clinical Observations Can Change Research Failures Into Successes
https://www.onclive.com/publications/oncology-live/2017/vol-18-no-20/clinical-observations-can-change-research-failures-into-successes

Oct 23rd, 2017 - Maurie Markman, MD One of the basic tenets of scientific investigation is the development of a hypothesis that is then tested in an attempt to prove or disprove its validity. In the clinical cancer domain, basic laboratory observations are followed by clinically relevant translational research strategies and, ultimately, human trials. In the history of clinical cancer investigation, there are m...

The Fat Wars
https://www.staging.medscape.com/viewarticle/882253

Jul 9th, 2017 - Hello and welcome. I am Dr George Lundberg and this is At Large at Medscape. I am about to fix my dinner and I do not know what to eat. Can you help me? You probably saw the official American Heart Association's (AHA) "Presidential Advisory" on dietary fats and cardiovascular disease, by 12 distinguished authors.[1] It was published in the AHA's own journal, Circulation, on June 15, 2017, with ...

The Fat Wars
https://www.medscape.com/viewarticle/882253

Jul 9th, 2017 - Hello and welcome. I am Dr George Lundberg and this is At Large at Medscape. I am about to fix my dinner and I do not know what to eat. Can you help me? You probably saw the official American Heart Association's (AHA) "Presidential Advisory" on dietary fats and cardiovascular disease, by 12 distinguished authors.[1] It was published in the AHA's own journal, Circulation, on June 15, 2017, with ...

Case Studies in Locally Advanced NSCLC
https://emedicine.medscape.com/viewarticle/900808

Case Studies in Locally Advanced NSCLC
https://www.medscape.com/viewarticle/900808

Living Alone Does Not Appear to Worsen Heart Disease
https://emedicine.medscape.com/viewarticle/910706

(Reuters Health) – For people with well-controlled heart disease, living alone isn't linked with a higher risk of cardiovascular problems, a large study suggests. For five years, researchers tracked more than 32,000 patients from 45 countries. All were living with stable coronary artery disease, which means the arteries that carry blood to the heart were narrowed or clogged but hadn't been caus...

Can We Afford the Cost of Myeloma Therapy?
https://emedicine.medscape.com/viewarticle/898450

CHICAGO — Over the past few years, the approval of several new drugs for multiple myeloma, as well as evolving strategies for stem cell transplant, have contributed to increased survival and improved quality of life for many patients with this disease. However, the new agents come with hefty price tags, and multiple myeloma has become a very expensive disease to treat. Can we afford it? Or not?...

Walking Just 4 Hours a Week Linked to Reduced Stroke Severity
https://emedicine.medscape.com/viewarticle/902222

Compared with those who are physically inactive, adults who routinely engaged in light to moderate physical activity prior to a stroke or transient ischemic attack were twice as likely to experience a mild event rather than a moderate or severe one, new research suggests. The retrospective study showed that more than half (52%) of the 925 people in two Swedish stroke registries were physically ...