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Clinical Edge Journal Scan Commentary: Multiple Sclerosis June 2022
https://www.mdedge.com/neurology/msresourcecenter/article/255056/multiple-sclerosis/clinical-edge-journal-scan-commentary
Mark Gudesblatt, MD

May 27th, 2022 - Mark Gudesblatt, MD Multiple sclerosis (MS) remains a complex disease with varied effects, some visible and clinically symptomatic and others invisible (eg, effects on cognition). However much we focus on the visible and uncovering the currently invisible effects, we must be aware of the effects of prior infection with SARS-CoV-2 (ie, post-acute COVID-19 syndrome, aka long COVID) in people with.

COVID-19 Vaccines Work Better and for Longer Than Expected Across Populations, Including Immunocompromised Individuals
https://www.medscape.com/viewarticle/974363

May 27th, 2022 - The mRNA vaccines are powerful in terms of preventing severe disease with COVID-19 across populations because of the multifaceted immune response they generate, a redundancy that can help among patients on agents which cause immunocompromise. Although antibodies from the vaccines will wane over time, or these antibodies can be less effective against new variants like Omicron, the vaccines do no...

Update on Rabies, TBE, and Cholera Vaccines Before Travel
https://www.medscape.com/viewarticle/974443

May 27th, 2022 - Healthcare providers should be aware of important updates to vaccine recommendations that could affect patients preparing to travel internationally this summer. This includes information about: New rabies pre-exposure prophylaxis guidelines (PrEP); The new tick-borne encephalitis (TBE) vaccine; and Updated cholera vaccine recommendations and a restart of Vaxchora manufacturing and distribution....

Breakthrough Infections May Be Less Contagious
https://www.medscape.com/viewarticle/974700

May 27th, 2022 - (Reuters) - Fully vaccinated individuals who get infected with the coronavirus spread the infection to fewer people and are contagious for less time compared to people who are partially vaccinated or unvaccinated, a small study from South Korea suggests. In 173 hospital workers with COVID-19, including 50 who had breakthrough infections, researchers found that the virus had been transmitted to ...

MRI Technique May Yield Clues to Long COVID Breathlessness
https://www.medscape.com/viewarticle/974705

May 27th, 2022 - (Reuters) - In people with lasting breathlessness after COVID-19, a special type of magnetic resonance imaging (MRI) reveals lung abnormalities that traditional imaging techniques do not detect, a small study shows. In 23 patients with shortness of breath lasting for months after COVID-19, including 11 who had not required hospitalization, the researchers performed hyperpolarized xenon 129MRI, ...

Elderly Still Make Up Most of the COVID-19 Deaths
https://www.medscape.com/viewarticle/974719

May 27th, 2022 - Editor's note: Find the latest COVID-19 news and guidance in Medscape's Coronavirus Resource Center. The number of daily COVID-19 deaths is dropping in the United States, but one fact has not changed in two-plus years of the pandemic: The elderly are still most at risk of dying from the virus. The seven-day moving average of COVID-related deaths is now 288, a number far lower than the peaks of ...

Previous COVID-19 or MIS-C does not protect kids from Omicron
https://www.eurekalert.org/news-releases/954167

May 27th, 2022 - Research drawing on the national Overcoming COVID-19 study, led by Boston Children’s Hospital, and the hospital’s own Taking On COVID-19 Together Group provides evidence that children who previously had COVID-19 (or the inflammatory condition MIS-C) are not protected against the newer Omicron variant. Vaccination, however, does afford protection, the study found. The findings, published in Natu...

Pfizer to Sell All Its Patented Drugs at Nonprofit Price in Low-Income Countries
https://www.medscape.com/viewarticle/974583

May 26th, 2022 - (Reuters) - Pfizer Inc will make all of its patented medicines including COVID-19 treatment Paxlovid and big-selling breast cancer drug Ibrance available at a not-for-profit price to 45 of the world's poorest countries, the drugmaker said on Wednesday. These countries lack good access to innovative treatments. It can take four to seven years longer for new treatments to become available in low-...

G20 Pandemic Fund Ploughs Ahead Amid Fears World Not Ready for Future Threats
https://www.medscape.com/viewarticle/974603

May 26th, 2022 - LONDON (Reuters) - A multi-billion dollar fund set up by G20 countries to help developing countries better prepare for pandemics could be operational within months, according to the World Bank. The bank – which will house the fund – said it was "proceeding quickly" to set up the facility, after releasing a white paper for consultation last week on how it might work. "Pandemic preparedness is a ...

Focus on Antivirals, Vaccines as Monkeypox Continues
https://www.medscape.com/viewarticle/974659

May 26th, 2022 - Since the first case of monkeypox on May 6, reports of outbreaks have come from multiple countries, with the UK, Spain, and Portugal in the lead, followed by Canada, Israel, and Australia, among others. The US has reported cases in Boston and New York City, and presumed cases have occurred in Utah and Florida. As of May 25, close to 350 cases, either suspected (83) or confirmed (265), have been...

Oncologists Flock to Chicago for ASCO, After 2 Years Online
https://www.medscape.com/viewarticle/974658

May 26th, 2022 - The biggest cancer conference in the world is back in person after 2 years online during the COVID pandemic. And it appears many are eager to attend the American Society of Clinical Oncology (ASCO) annual meeting in person now that they can. By early May, ASCO already had 30,000 registrations, of which 80% were in person — there were 27,000 hotel reservations. "That's almost identical to where ...

US Making COVID Antiviral Drug More Available at Test Sites
https://www.medscape.com/viewarticle/974667

May 26th, 2022 - Editor's note: Find the latest COVID-19 news and guidance in Medscape's Coronavirus Resource Center. WASHINGTON (AP) — The White House on Thursday announced more steps to make the antiviral treatment Paxlovid more accessible across the U.S. as it projects COVID-19 infections will continue to spread over the summer travel season. The nation's first federally backed test-to-treat site is opening ...

A Plant-Based COVID Vaccine: Which Patients Would Benefit?
https://www.medscape.com/viewarticle/974663

May 26th, 2022 - Editor's note: Find the latest COVID-19 news and guidance in Medscape's Coronavirus Resource Center. The first plant-based COVID vaccine ever produced was approved on February 24 in Canada for adults aged 18 to 64 years. Covifenz, manufactured by Medicago, is to be administered in two intramuscular doses on day 0 and day 21. The originality of this new vaccine lies in its use of recombinant spi...

Novavax Missed Its Global Moonshot but Is Angling to Win Over mRNA Defectors
https://www.medscape.com/viewarticle/974670

May 26th, 2022 - Editor's note: Find the latest COVID-19 news and guidance in Medscape's Coronavirus Resource Center. Novavax hitched its wagon to the global coronavirus pandemic. Before most Americans truly grasped the scope of the danger, the small Maryland biotech startup had secured $1.6 billion in U.S. funding for its covid vaccine. Its moonshot goal: delivering 2 billion shots to the world by mid-2021. Al...

More Than 200 Monkeypox Cases Confirmed in 21 Countries
https://www.medscape.com/viewarticle/974681

May 26th, 2022 - The global tally of monkeypox cases has surpassed 200 and continues to increase daily, reaching across 21 countries, according to the latest report from the European Centre for Disease Prevention and Control. On Wednesday, the agency reported 219 confirmed cases worldwide, including 9 in the U.S. and 71 in the U.K. Later that day, the U.K. reported 7 more cases, bringing the global total to 226...

Study: Medicine for inflammatory bowel disease may protect against severe COVID-19
https://www.eurekalert.org/news-releases/954063

May 26th, 2022 - Getting the COVID-19 vaccination strengthened one type of immune response to the SARS-CoV-2 virus in inflammatory bowel disease (IBD) patients even though they were taking immunosuppressant medication, according to investigators at Cedars-Sinai. The findings of two studies focused on this topic have been published in the journals IBD, of the Crohn’s & Colitis Foundation, and Frontiers in Immuno...

An alarming prevalence of smell, taste loss during COVID’s delta surge
https://www.eurekalert.org/news-releases/953972

May 26th, 2022 - COLUMBUS, Ohio – The loss of smell and taste with a COVID-19 infection during the delta surge was a prevalent symptom and wasn’t prevented by vaccination, new research suggests. The small Ohio State University study also found that some people with the earliest COVID-19 infections were continuing to experience loss of these senses months later and didn’t even realize it. In participants with ac...

Monkeypox: What Do Experts Actually Think?
https://www.medscape.com/viewarticle/974461

May 25th, 2022 - This discussion was recorded on May 20, 2022. This transcript has been edited for clarity. Robert D. Glatter, MD: Welcome. I'm Dr Robert Glatter, medical advisor for Medscape Emergency Medicine. Today, we have a distinguished panel joining us to discuss a recent outbreak of the rare and potentially fatal monkeypox virus that initially began in clusters in the United Kingdom in early May, with c...

Germany's Vaccine Panel Says One COVID Shot Enough for Children
https://www.medscape.com/viewarticle/974524

May 25th, 2022 - FRANKFURT (Reuters) - Germany's vaccine advisory panel on Tuesday said one COVID-19 shot was enough for healthy five- to 11-year-olds because most of them had already undergone an infection, maintaining its cautious approach. The view by the panel of 18 appointees, known as STIKO, contrasts with European Union regulators' approval for a two-shot regimen in that age group. U.S. regulators last w...

Videos May Not Increase Vaccinations in IBD
https://www.medscape.com/viewarticle/974590

May 25th, 2022 - SAN DIEGO – Video and text messaging may not increase the proportion of people with inflammatory bowel disease (IBD) who get influenza vaccinations. Although patients who received the messages expressed greater intention to get the vaccinations in a trial of the two methods, they didn't follow through and get the shots, said Keren Appel, MD, a pediatric gastroenterologist at Children's Hospital...