About 42,480 results

Patent Foramen Ovale Clinical Practice Guidelines (SCAI, 2022)

May 27th, 2022 - Clinical practice guidelines on the management of patent foramen ovale (PFO) from the Society for Cardiovascular Angiography and Interventions (SCAI) were published in May 2022 in  JSCAI.[1] In patients aged 18-60 years who have had a PFO-related stroke, PFO closure is strongly recommended instead of antiplatelet therapy alone. For patients aged 60 years and older with a history of PFO-related ...

Harnessing the immune system to treat traumatic brain injury in mice

May 26th, 2022 - A therapeutic method for harnessing the body’s immune system to protect against brain damage is published today by researchers from the Babraham Institute’s Immunology research programme. The collaboration between Professor Adrian Liston (Babraham Institute) and Professor Matthew Holt (VIB and KU Leuven; i3S-University of Porto) has produced a targeted delivery system for boosting the numbers o...

Gut bacteria can make blood pressure medication less effective

May 26th, 2022 - A new study from The University of Toledo College of Medicine and Life Sciences has shown gut bacteria can reduce the effectiveness of certain blood pressure drugs. The research, published this month in the journal Hypertension, offers the first clues to what has been an elusive mystery — why do some people not respond well to medication? “High blood pressure is often called a silent killer bec...

Can TTR Predict Better Outcomes in Renal Denervation Patients?

May 26th, 2022 - New support for using time in target range (TTR) to assess the clinical impact of renal denervation and lifetime burden of disease in patients with uncontrolled hypertension comes from two analyses presented at EuroPCR 2022. Between 6- and 36-month follow-up in the Global SYMPLICITY Registry, the major adverse cardiovascular event (MACE) rate was 2.9% in patients who spent more than 50% in TTR ...

No-implant interatrial shunt remains patent at a year
Richard Mark Kirkner

May 25th, 2022 - The first in-human trials of a no-implant approach to interatrial shunting to alleviate heart failure symptoms have shown a signal that the procedure reduces peak exercise wedge pressure in recipients a month afterward, according to early trial results. Colin M.

Could Neutrophil Counts Predict Cardiovascular Outcomes?

May 25th, 2022 - MILAN — Increases in neutrophil counts appear to be causally associated with incident coronary artery disease (CAD) and myocardial infarction (MI), suggests a novel analysis that combined observational and genetic data. The study initially confirmed the association between increased neutrophil counts and coronary artery disease, ischemic cerebrovascular disease, ischemic stroke, and vascular de...

No-Implant Interatrial Shunt Remains Patent at a Year

May 25th, 2022 - The first in-human trials of a no-implant approach to interatrial shunting to alleviate heart failure symptoms have shown a signal that the procedure reduces peak exercise wedge pressure in recipients a month afterward, according to early trial results. Colin M. Barker, MD, reported 30-day results of 31 patients who had no-implant interatrial shunting for heart failure across three studies, at ...

Vascular Risk Factors for Dementia Vary With Age

May 25th, 2022 - Vascular risk factors for dementia vary with age, new research suggests. New data from the Framingham Heart Study show that high systolic blood pressure (SBP) and diabetes are the most important vascular risk factors for increased 10-year incident dementia at age 55, whereas heart disease was identified as a more important risk factor for dementia at age 65. These findings, researchers note, hi...

Does the size of air pollution particles affect a person’s risk of death from stroke?

May 25th, 2022 - EMBARGOED FOR RELEASE UNTIL 4 P.M. ET, WEDNESDAY, MAY 25, 2022 MINNEAPOLIS – Living in areas with higher air pollution is associated with an increased risk of in-hospital death from stroke, and the risk varies depending on the size of the air pollution particles, according to a new study published in the May 25, 2022, online issue of Neurology®, the medical journal of the American Academy of N...

Singapore scientists pinpoint how non-alcoholic fatty liver disease increases risk of vascular diseases

May 25th, 2022 - These findings by scientists from Nanyang Technological University, Singapore (NTU Singapore) and the National University of Singapore (NUS) shed light on why the leading cause of mortality in NAFLD patients is cardiovascular complications, instead of liver damage. NAFLD is a general term for liver diseases affecting patients who drink little to no alcohol. It is mainly characterised by having...

Missing link between Alzheimer's and vascular disease found?

May 25th, 2022 - NEW YORK, NY -- For more than 20 years, scientists have known that people with hypertension, diabetes, high cholesterol, or obesity have a higher likelihood of developing Alzheimer’s disease. The conditions can all affect the brain, damaging blood vessels and leading to strokes. But the connection between vascular disease in the brain and Alzheimer’s has remained unexplained despite the intense...

Urinary incontinence in transfeminine patients
K. Ashley Brandt, DO

May 24th, 2022 - Whether your patient is a cisgender female or a transfeminine patient, urinary incontinence is unfortunately common and can have a significant negative effect on a person’s quality of life. While the incidence of incontinence is relatively well established in the cisgender population, these statistics remain elusive among transfeminine individuals.

Millions of Single-Cell Analyses Yield Most Comprehensive Human Cell Atlas Yet
NIH Director's Blog;

May 24th, 2022 - There are 37 trillion or so cells in our bodies that work together to give us life. But it may surprise you that we still haven’t put a good number on how many distinct cell types there are within those trillions of cells. That’s why in 2016, a team of researchers from around the globe launched a historic project called the Human Cell Atlas (HCA) consortium to identify and define the hundreds o...

Better Biopsies? High-Speed 3D Cameras Could Be the Future

May 24th, 2022 - Biopsies haven't changed much in the more than 100 years they've been in medical use: Tissue (a cluster of cells) is cut from the body, embedded into a block, thinly sliced, mounted on a slide, and stained with dye. A pathologist then analyzes the sample with a microscope. Results come back in 2 to 10 days while the patient and their family nervously wait.  Engineers at Columbia University are ...

Low stroke risk in patients with very narrowed neck arteries

May 24th, 2022 - OAKLAND, Calif. — The risk of having a future stroke caused by a severe blockage in an artery in the neck that is not currently causing any symptoms is so low that most patients with this condition — asymptomatic carotid stenosis — could potentially be treated with the newest medications and may not require surgery, new Kaiser Permanente research suggests. “The question of how to best treat pat...

More cardiovascular disease found in lean people with non-alcoholic fatty liver disease than in those who are overweight with the same condition

May 24th, 2022 - Bethesda, MD (May 13, 2021) — Those with a normal body mass index (BMI) with non-alcoholic fatty liver disease (NAFLD) are more likely to have cardiovascular disease than those who are overweight or living with obesity, according to research selected for presentation at Digestive Disease Week® (DDW) 2022. Roughly 25 percent of adults in the U.S. have NAFLD, a term for various conditions of the ...

High social vulnerability predicts worse long-term outcomes after traumatic injury

May 24th, 2022 - Traumatic injuries — such as physical injuries resulting from a car accident, fall, gunshot or stabbing — are one of the most common causes of impairment and disability worldwide. A team of investigators led by Juan P. Herrera-Escobar, MD, MPH, of the Brigham’s Center for Surgery and Public Health, found that living in an area with higher social vulnerability is strongly associated with worse m...

Thrombolysis Safe in Stroke Patients on Oral Anticoagulants

May 23rd, 2022 - Intravenous thrombolysis (IVT) for acute stroke appears safe for patients who have recently received direct oral anticoagulant (DOAC) therapy, a new observational study suggests, prompting researchers to ask whether guidelines that restrict its use should be updated. Researchers found that DOAC users were significantly less likely to develop symptomatic intracerebral hemorrhage (sICH) after IVT...

Hearing, Vision Loss Combo a Colossal Risk for Cognitive Decline

May 23rd, 2022 - The combination of hearing loss and vision loss is linked to an eightfold increased risk of cognitive impairment, new research shows. Investigators analyzed data on more than 5 million US seniors. Adjusted results show that participants with hearing impairment alone had more than twice the odds of also having cognitive impairment, while those with vision impairment alone had more than triple th...

Fewer Teens Giving Birth, but Cases Are More Complex

May 23rd, 2022 - Debra Katz, CNM, has noticed a shift in the number of teenagers coming to the teen obstetrics program at St. Joseph's Medical Center in Paterson, New Jersey. A decade ago, about 30 adolescents gave birth in a given month; now, that figure is closer to 20, said Katz, chief of the nurse midwifery service at the center. Katz's observations mirror a national trend: The rate of teen births is fallin...