About 20,620 results

Psychiatric Risks Subside Before Neurologic Risks After COVID-19
Pulmonology Advisor

Oct 3rd, 2022 - Following COVID-19 infection, the risk for developing neurological disorders remains high after 2 years, while the risk for psychiatric disorders subsides earlier. These are the findings of a study published in Lancet Psychiatry. Researchers analyzed outcome data in a multinational, retrospective cohort study. They obtained data from the TriNetX electronic health records network between January...

I Am Not Fine: The Heavy Toll Cancer Takes

Sep 30th, 2022 - PARIS — "I thought I was as exhausted, and isolated, and neglected as I could get, and then he came home." Those were the words of Kate Washington, PhD, from Sacramento, California, as she gave a moving account of the immense burden she felt as caregiver to her husband with cancer. She was taking part in the session, "I am FINE: Frustrated * Isolated * Neglected * Emotional," at the European So...

Ketamine and Psilocybin Update in Treatment-Resistant Depression
Clinical Advisor

Sep 29th, 2022 - Highlights from Psych Congress 2022 include studies on the efficacy of psychedelics in patients with treatment-resistant depression. Two studies found that treatment with COMP360 psilocybin therapy reduced depression symptoms in patients with treatment-resistant depression, and a third study found that using precision medicine for ketamine dosing may decrease the high efficacy-low effectiveness...

Depression, Anxiety Reduce Likelihood of Achieving Minimal Disease Activity in PsA
Dermatology Advisor

Sep 29th, 2022 - Anxiety and depression are associated with a lower probability of achieving sustained minimal disease activity (MDA) in psoriatic arthritis (PsA), according to study results published in Arthritis Care & Research (Hoboken). Patients with PsA were assessed every 6 to 12 months between 2008 and 2017. Researchers defined MDA as having met criteria for at least 2 consecutive visits and was determin...

Electroacupuncture Effective Treatment for Insomnia in Depression
Clinical Pain Advisor

Sep 27th, 2022 - Study data published in JAMA Network Open support the efficacy of electroacupuncture for the treatment of insomnia in patients with depression. Compared with a placebo, electroacupuncture was associated with significantly improved sleep quality over 32 weeks of follow-up. This randomized controlled trial was conducted from September 1, 2016 to July 30, 2019 at 3 tertiary hospitals in Shanghai, ...

Atopic Dermatitis Not Tied to Neuropsychiatric Disorders in Children
Psychiatry Advisor

Sep 27th, 2022 - Atopic dermatitis (AD) does not have a substantial effect on the overall risk for neuropsychiatric disorders in children, although disease severity and age may be modifying factors, researchers reported in study findings published in the Journal of the European Academy of Dermatology and Venereology. The retrospective cohort study evaluated the risk for major neuropsychiatric disorders in child...

Unconventional Wisdom: Major Depression Tied to Childhood Trauma Is Treatable

Sep 27th, 2022 - Despite a higher symptom burden, patients with major depressive disorder (MDD) and a history of childhood trauma (CT) can achieve significant recovery following treatment with a combination of pharmacotherapy and psychotherapy, new research suggests. Results from a meta-analysis of 29 studies from 1966 to 2019, which included almost 7000 adults with MDD, showed that more than 60% reported a his...

Deep Brain Stimulation Effective for OCD, but Barriers Persist

Sep 27th, 2022 - Deep brain stimulation (DBS) is safe and effective for individuals with severe obsessive–compulsive disorder (OCD) that has been resistant to conventional therapy, a meta-analytic review confirms. "DBS is a viable option for treatment-resistant OCD that can be expected to produce significant clinical benefit in about 2 out of 3 cases," study investigator Wayne Goodman, MD, chair, Department of ...

Major Depressive Disorder: A Complex Disease Requiring a Compassionate Response

Sep 27th, 2022 - Joseph Goldberg, MD, presents aspects of the treatment of major depressive disorder (MDD) for aspiring psychiatrists, describing the personal approach that allows for empathy with patients, but also the need for an objective clinical perspective that allows for sound assessment. Together, Dr Goldberg suggests, these values create a balanced, pragmatic approach marked by a plotting of reasonable...

Learning From Patient Experiences in Major Depressive Disorder

Sep 27th, 2022 - Joseph Goldberg, MD, reveals important lessons that he learned from his patients with major depressive disorder (MDD). One lesson is that "life is a big stress test" and, in this context, the treatment of patients with MDD isn't just about running down a list of symptoms but also assessing the patient's capacity for resilience, coping with adversity, and real-world problem-solving. Dr Goldberg ...

Problem-Solving in the Treatment of Major Depressive Disorder

Sep 27th, 2022 - Joseph Goldberg, MD, reflects on his lifelong process of learning and the mentors who shaped his career. Drawing upon his earlier experience in the world of research, Dr Goldberg asserts that the scientific approach is very applicable to the kind of problem-solving needed in the psychiatric practice with patients. Dr Goldberg also highlights the importance of communicating the potential risks a...

Timing of Food Intake a Novel Strategy for Treating Mood Disorders?

Sep 26th, 2022 - Shift workers who confine their eating to the daytime may experience fewer mood symptoms compared to those who eat both day and night, new research suggests. Investigators at Brigham and Women's Hospital, Boston, Massachusetts, created a simulated nightwork schedule for 19 individuals in a laboratory setting. Participants then engaged in two different meal timing models ― daytime-only meals (DM...

Lurasidone Improves Health-Related QOL in Patients With Bipolar Disorder
Neurology Advisor

Sep 23rd, 2022 - Patients with bipolar depression had improved health-related quality of life (HRQoL) following lurasidone monotherapy, according to findings published in Current Medical Research and Opinion. Researchers conducted a randomized, double-blind, placebo-controlled trial in North America, Europe, Asia, and Africa. Patients with bipolar disorder and depression were randomly assigned to receive either...

C-Reactive Protein Levels May Predict SSRI Success

Sep 23rd, 2022 - Individuals with depression who had high levels of C-reactive protein responded poorly to selected serotonin reuptake inhibitors compared to those with lower CRP levels, based on data from more than 900 patients. C-reactive protein (CRP) has been shown to predict antidepressant treatment outcomes in depressed patients, but previous studies have been small and under restricted conditions, and da...

Risk Prediction Models Identify Presymptomatic Alzheimer's Disease

Sep 23rd, 2022 - The study covered in this summary was published on medRxiv.org as a preprint and has not yet been peer reviewed. Key Takeaway Risk prediction models based on noncognitive metrics predict both Alzheimer's dementia and cognitive impairment. Why This Matters The development of noncognitive risk prediction models for patients with Alzheimer's disease prior to the presentation of symptoms may enable...

Trans-auricular VNS 'Very Clever' for Parkinson's Disease

Sep 23rd, 2022 - Trans-auricular vagus nerve stimulation (taVNS) is feasible, well-tolerated, and may improve motor function in patients with Parkinson's Disease (PD), new research suggests. The field of noninvasive brain stimulation in PD is in its infancy, but emerging research shows it is a promising approach for some patients, lead study author Vanessa K. Hinson, MD, PhD, professor of neurology and director...

Resistance Training Tied to Improvements in Parkinson's Symptoms

Sep 23rd, 2022 - Resistance training (RT) can help improve several symptoms of Parkinson's Disease (PD) — but is not superior to other physical activities, new research suggests. A meta-analysis, which included 18 randomized controlled trials and more than 1000 patients with PD, showed that those who underwent RT had significantly greater improvement in motor impairment, muscle strength, and mobility/balance th...

New Fathers' Brains Shrink -- and That's OK; Reasons to Get the Omicron Booster; and Open-Door Psychiatric Wards Gain Favor

Sep 22nd, 2022 - New Fathers' Brains Shrink — and That's OK The brains of first-time fathers appear to shrink after the birth of their child. But that's not necessarily a bad thing, according to new research from the Instituto de Investigación Sanitaria Gregorio Marañón in Madrid, Spain, and the University of Southern California. The study was published September 4 in Cerebral Cortex. The research compared MRIs...

Individuals With Depression More Sensitive to Missed Opportunities
Neurology Advisor

Sep 21st, 2022 - A study published in the Journal of Affective Disorders found that individuals with symptoms of depression were more sensitive to missed opportunities. Individuals with depression, defined as a Beck Depression Inventory Second Edition (BDI-II) score >13, and healthy controls were recruited for this study at the Shaanxi Normal University in China. Participants underwent a sequential risk-taking ...

Toward a New Open-Door Model for Psychiatric Wards

Sep 21st, 2022 - If isolated, patients with mental disorders may end up having higher levels of social impairment. This has led several hospitals in Spain to set up open-door departments that are more accessible. The purpose of the open-door model is to help remove the stigma from individuals who need to be admitted to a psychiatric ward because they have a mental disorder. Traditional Locked Wards According to...