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About 5,970 results

Type 1 vs Type 2 Youth-Onset Diabetes: Which Is Worse for the Eyes?
https://www.medpagetoday.com/ophthalmology/generalophthalmology/95979

Dec 2nd, 2021 - Type 2 diabetes may pose a greater threat to the eyes than type 1 diabetes, a retrospective review suggested. In over 600 individuals with youth-onset diabetes, every diabetic eye-related complication assessed was more common among those with type 2 diabetes versus those with type 1 diabetes, reported Brian G. Mohney, MD, of the Mayo Clinic in Rochester, Minnesota, and colleagues in JAMA Ophtha...

Year in Review: Multiple Sclerosis
https://www.medpagetoday.com/neurology/multiplesclerosis/95981

Dec 2nd, 2021 - One of the first questions posed by multiple sclerosis (MS) experts in 2021 is still being asked today: How can people with MS best protect themselves against SARS-CoV-2? As early as January 13, the National MS Society advised most people with relapsing and progressive forms of MS to get a COVID-19 vaccine. "The risks of COVID-19 disease outweigh any potential risks from the vaccine," society e...

Diabetes & Psych Disorders; FDA Pushes Schizophrenia Film Review Date; #Shadowwork
https://www.medpagetoday.com/psychiatry/generalpsychiatry/95955

Dec 1st, 2021 - People with type 2 diabetes had a high prevalence of many psychiatric conditions, including sleep disorders, binge eating disorder, substance use disorder, anxiety, bipolar disorder, and more, according to a meta-analysis of 245 observational studies. (Diabetologia) The FDA granted fast track designation to BNC210 -- an oral proprietary selective negative allosteric modulator of the α7 nicotini...

Diabetes Risk Higher for Transwomen vs Cisgender Females
https://www.medpagetoday.com/endocrinology/diabetes/95937

Nov 30th, 2021 - Transwomen may face a higher risk for developing type 2 diabetes than cisgender women, a new study suggested. In a review of new data from the Study of Transition Outcomes and Gender (STRONG) cohort, transwomen had a 30% higher odds of prevalent type 2 diabetes compared with the cisgender female population in an adjusted model (OR 1.3, 95% CI 1.1-1.5), reported Noreen Islam, MD, MPH, of Emory U...

Omicron in Canada; Fauci: 'Inevitably It Will Be Here'; Efficacy on Merck Pill Sinks
https://www.medpagetoday.com/infectiousdisease/covid19/95907

Nov 29th, 2021 - Note that some links may require registration or subscription. Canada announced that it found two cases of the new Omicron variant; other cases have already been reported in the U.K., Germany, Australia, and several other nations. (NPR) Thirteen of the 61 people who tested positive for COVID-19 after flying to Amsterdam from South Africa, on just two flights, had the variant. (BBC) "Inevitably ...

DIY Insulin Delivery System Guide; The Obesity Society Turns 40; $35 Cap on Insulin?
https://www.medpagetoday.com/endocrinology/generalendocrinology/95876

Nov 28th, 2021 - A 64-year-old man was cured of his lifelong type 1 diabetes after receiving an investigational treatment that turns stems cells into insulin-secreting islet cells, as part of a clinical trial led by Vertex Pharmaceuticals. (New York Times) A new review in The Lancet Diabetes & Endocrinology is offering guidance to healthcare professionals working with patients using do-it-yourself automated ins...

More Data Link Psychiatric Disorders to Higher COVID Mortality
https://www.medpagetoday.com/psychiatry/generalpsychiatry/95835

Nov 23rd, 2021 - While people with certain psychiatric disorders were less likely to test positive for COVID-19, they still faced higher mortality than the general population, researchers reported. Compared with the 11.91% COVID-19 positivity rate in the general population in 2020, individuals with schizophrenia or mood disorders saw lower positivity rates (9.86% each), according to Antonio L. Teixeira, MD, PhD...

Imcivree Considered for Expanded Label; Semglee Hits Shelves; Buphenyl for T2D?
https://www.medpagetoday.com/endocrinology/generalendocrinology/95785

Nov 21st, 2021 - The FDA accepted a priority review of a supplemental new drug application for setmelanotide (Imcivree), a melanocortin-4 receptor agonist, for the treatment of Bardet-Biedl syndrome and Alström syndrome, Rhythm Pharmaceuticals announced. The FDA assigned a Prescription Drug User Fee Act (PDUFA) goal date of March 16, 2022. AstraZeneca pulled dapagliflozin (Forxiga) for patients with type 1 diab...

Stillbirth Risk Spiked With Delta
https://www.medpagetoday.com/infectiousdisease/covid19/95794

Nov 19th, 2021 - For pregnant women with COVID-19 during the Delta period, the risk for stillbirth was four times higher if they had their diagnosis at delivery while mortality was increased fivefold in a small study from Mississippi, according to two CDC reports. From March 2020 to September 2021, the risk for stillbirth was 90% higher among women who had a COVID-19 diagnosis at delivery versus those who did n...

Another Study Confirms Gout Benefit With SGLT2 Inhibitors
https://www.medpagetoday.com/endocrinology/diabetes/95777

Nov 19th, 2021 - Patients with type 2 diabetes taking sodium-glucose cotransporter-2 (SGLT2) inhibitors saw a lower risk for gout, a Taiwanese cohort study found. Compared with patients taking DPP-4 inhibitors, those on an SGLT2 inhibitor had an 11% reduced risk for gout after adjusting for potential risk factors (HR 0.89, 95% CI 0.82-0.96), according to Chi-Jung Chung, PhD, of China Medical University in Taiwa...

Weight Loss Win for Weekly Injections of Novel Amylin Agent in Early Trial
https://www.medpagetoday.com/endocrinology/obesity/95757

Nov 18th, 2021 - The investigational long-acting amylin analogue cagrilintide (AM833) helped people with overweight or obesity, but no diabetes, shed pounds in a phase II trial. In the randomized trial, all doses of the novel once-weekly injectable treatment yielded significantly greater weight loss than placebo, reported David C.W. Lau, MD, of the University of Calgary Cumming School of Medicine in Canada, and...

New Jardiance Indication? Bariatric Surgery for NASH; ICER Reviews Tirzepatide
https://www.medpagetoday.com/endocrinology/generalendocrinology/95628

Nov 14th, 2021 - The FDA accepted a supplemental new drug application for empagliflozin (Jardiance) as a treatment for heart failure independent of left ventricular ejection fraction in patients with or without diabetes based on the phase III EMPEROR-Preserved trial, Boehringer Ingelheim and Eli Lilly announced. Bariatric surgery -- either Roux-en-Y gastric bypass or sleeve gastrectomy -- was associated with a ...

Mental Stress-Induced CV Events; Telling Retina Scans; Bedtime and Heart Health
https://www.medpagetoday.com/cardiology/prevention/95549

Nov 9th, 2021 - Theories abound regarding the mechanism behind the link between mRNA vaccines and myocarditis. (Wall Street Journal) Registry data show that COVID-19 patients with ischemic heart disease were not at a disadvantage in survival, whereas those with heart failure experienced excess in-hospital deaths. (European Heart Journal) A larger study confirmed the link between mental stress-induced myocardia...

No, Aluminum in Vaccines Doesn't Cause Type 1 Diabetes
https://www.medpagetoday.com/pediatrics/vaccines/95525

Nov 8th, 2021 - The recommended childhood vaccination schedule does not increase incidence of type 1 diabetes, according to a cohort study of over half a million children. There was no association between cumulative antigen exposure or average days unvaccinated and type 1 diabetes. Moreover, cumulative exposure to aluminum greater than 3 mg -- aluminum being a common adjuvant used to elicit stronger immune res...

Phthalates in Fast Food; Testosterone Tx Popular; Spain's Plan to Curb Kids' Obesity
https://www.medpagetoday.com/endocrinology/generalendocrinology/95343

Oct 31st, 2021 - Phthalates -- a class of endocrine-disrupting chemicals commonly found in plastics -- were found to be highly prevalent in many fast foods, like cheeseburgers and burritos. (Gizmodo) Even patients with a longer duration of thyroid eye disease responded well to treatment with teprotumumab (Tepezza), according to the OPTIC-X study. Also, patients who initially had an insufficient response or a fl...

UPDATE 2-Novo shares at record as diabetes drug growth surpasses forecasts
https://www.reuters.com/article/novo-nordisk-outlook/update-2-novo-shares-at-record-as-diabetes-drug-growth-surpasses-forecasts-idUSL1N2RP1F9

Oct 29th, 2021 - (Adds details, updates share price move) COPENHAGEN, Oct 29 (Reuters) - Drug maker Novo Nordisk raised its forecast for sales and operating profit for the full year on Friday after stronger than expected sales in the third quarter, sending its shares to a record high. The world’s biggest producer of diabetes drugs now expects both sales and operating growth of between 12% and 15%, up from 10-13...

Dialysis Patients Mount Best COVID Vax Response After Third Dose
https://www.medpagetoday.com/nephrology/esrd/95306

Oct 28th, 2021 - Even people with end-stage renal disease (ESRD) were able to bolster an immune response to the COVID-19 vaccine, researchers reported. According to a systematic review and meta-analysis of 32 studies, the overall immunogenicity rate for people on dialysis was 86% (95% CI 81-89), noted Chih-Hsiang Chang, MD, of Chang Gung Memorial Hospital in Linkou, Taiwan, and colleagues in JAMA Network Open. ...

SGLT-2 Inhibitors Cleared of Bone Fracture Qualms in Older T2D Patients
https://www.medpagetoday.com/endocrinology/diabetes/95290

Oct 27th, 2021 - SGLT-2 inhibitors were deemed safe for the bones in older patients with type 2 diabetes, a new study reassured. No significant differences were seen in regards to fracture risk when comparing new SGLT-2 inhibitor users versus new DPP-4 inhibitor users (HR 0.90, 95% CI 0.73-1.11) or GLP-1 receptor agonist users (HR 1.00, 95% CI 0.80-1.25), reported Elisabetta Patorno, MD, DrPH, of Brigham and Wo...

Cataracts and Vascular Health; Risky Stimulant Use; CEC Adjudication Flaws
https://www.medpagetoday.com/cardiology/prevention/95267

Oct 26th, 2021 - Does cataract surgery predict vascular and all-cause mortality a decade later? (British Journal of Ophthalmology) The "5 As" -- assess, advise, agree, assist, and arrange -- were highlighted in the American Heart Association's statements on how to promote healthy lifestyles to patients of all cardiovascular risk categories and special populations. (Circulation) CDC found that the proportion of ...

Expanding Obesity Coverage; Tymlos for Male Osteoporosis; T1D Stem Cell Tx Success
https://www.medpagetoday.com/endocrinology/generalendocrinology/95211

Oct 24th, 2021 - If pushed through, the Treat and Reduce Obesity Act would expand access to obesity treatment, using Medicare Part D to cover anti-obesity medication and behavioral therapy. (The Hill) One way to potentially help thwart excess weight in infants: a good night's sleep. "In this study, we found that not only shorter nighttime sleep, but more sleep awakenings, were associated with a higher likelihoo...