About 46,313 results

Low androgen in kidney recipients tied to diabetes
Miriam E. Tucker

Oct 22nd, 2021 - Low androgen levels appear to be linked to the development of posttransplantation diabetes mellitus (PTDM) in male kidney transplant recipients, new research suggests. London_England/Thinkstock Among 243 men who did not have diabetes prior to undergoing kidney transplantation, levels of both dihydrotestosterone (DHT) and testosterone were inversely related to the risk for developing diabetes th.

No Benefit to Intensifying Diabetes Meds at Hospital Discharge

Oct 21st, 2021 - Some older folks discharged from the hospital left with a more intense -- and possibly unnecessary -- treatment regimen for their diabetes, according to findings from the VA health system. In a retrospective study of over 28,000 patients ages 65 and older with type 2 diabetes, about 11% were discharged with an intensified regimen, which seemed to yield a mixed bag of outcomes, as these patients...

A 70-year-old man presents with firm papules on his hand and fingers
Donna Bilu Martin, MD, Susannah Berke, MD

Oct 21st, 2021 - Granuloma annulare (GA) is a benign cutaneous disorder with an unknown cause. All races and ages may be affected, although women are more often affected than men.

Child Mental Health Emergency; Lybalvi Hits Shelves; Vanessa Bryant Psych Eval

Oct 20th, 2021 - The American Academy of Pediatrics (AAP), American Academy of Child and Adolescent Psychiatry, and the Children's Hospital Association have joined forces to declare a national emergency in children's mental health, largely due to the COVID-19 pandemic. "Today's declaration is an urgent call to policymakers at all levels of government -- we must treat this mental health crisis like the emergency...

Tender Annular Plaque on the Thigh
Bao Vincent K. Ho, BS, Spyros M. Siscos, MD et. al.

Oct 20th, 2021 - The Diagnosis: Ecthyma Gangrenosum Histopathology revealed basophilic bacterial rods around necrotic vessels with thrombosis and edema (Figure). Blood and tissue cultures grew Pseudomonas aeruginosa.

FDA Looks Closer at Myocarditis; Cognition and DOACs; Silver Lining of Lockdowns?

Oct 19th, 2021 - The American Heart Association warns that progress is slowing in national care for ST-segment elevation myocardial infarction. (Circulation) FDA's internal deliberations on myocarditis risk will delay its decision on authorizing the Moderna COVID-19 vaccine for adolescents. (Wall Street Journal) Takotsubo syndrome disproportionately affects older women in the U.S., though its incidence is risin...

Genomic Profiling of Mycobacterium tuberculosis Strains, Myanmar

Oct 19th, 2021 - Tuberculosis (TB) is the infectious disease that causes the most deaths worldwide (≈5,000/day) (1). Of major concern is the increasing prevalence of drug resistance worldwide (1). There are different forms of TB drug resistance: pre‒multidrug-resistant TB (pre‒MDR TB, resistant to 1 of 2 first-line drugs: isoniazid or rifampin); multidrug-resistant TB (MDR TB, resistant to 2 first-line drugs: i...

Bordetella hinzii Pneumonia and Bacteremia in a Patient with SARS-CoV-2 Infection

Oct 19th, 2021 - Since the December 2019 beginning of the coronavirus disease (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus (SARS-CoV-2), there have been >180 million cases and >3.9 million deaths worldwide (1). Severe bacterial and fungal co-infections are a major concern with COVID-19 and increase disease mortality (2). The genus Bordetella comprises >10 known species of small, ...

Ghrelin Aids Weight Loss; FDA Says Cut Salt; More Bariatric Surgeries With Medicaid

Oct 17th, 2021 - Higher levels of fasting ghrelin helped induce abdominal visceral fat loss and improved insulin sensitivity in people who followed the green-Mediterranean diet. "The findings suggest fasting ghrelin levels may serve as a valuable indicator of cardiometabolic health following weight loss," said senior study author Iris Shai, PhD, of Harvard T.H. Chan School of Public Health in Boston, in a state...

Walk With a Doc: Patients, Physicians Make Strides Together

Oct 15th, 2021 - Columbus, Ohio–based cardiologist David Sabgir, MD, was a year into private practice when he realized something needed to change. "I realized I couldn't do this," says Sabgir. "I didn't want to have these fruitless conversations for the next 35 years, get a gold watch, and be done with it." The fruitless conversations are those that play on repeat every day in medical practices across the count...

High-Intensity Exercise, Not Pilates, Builds Bone in Older Women

Oct 15th, 2021 - An 8-month high-intensity resistance and impact training program (HiRIT, Onero) led to greater gains in lumbar spine bone mineral density (BMD) and leg/back strength than a low-intensity Pilates-based program (Buff Bones). These findings are from the Medication and Exercise for Osteoporosis (MEDEX-OP) trial, which included 115 postmenopausal women with low bone mass. Patients were randomly assi...

Birth Control Pills May Curb PCOS-Related Diabetes Risk

Oct 14th, 2021 - Certain oral contraceptives were associated with a lower risk for type 2 diabetes and prediabetes in women with polycystic ovary syndrome (PCOS), according to a retrospective, population-based study. An analysis of 64,051 women with PCOS found an approximately twofold higher risk for type 2 diabetes (adjusted HR 2.04, 95% CI 1.89-2.20, P<0.001) and dysglycemia (aHR 1.87, 95% CI 1.78-1.97, P<0.0...

Study Shines Light on Pattern of Incident Fractures in Type 1 Diabetes Patients

Oct 14th, 2021 - Newly treated individuals with type 1 diabetes (T1D) not only have a higher overall incidence of fractures but are also more likely to experience fractures at distal sites. These findings were published in  Osteoporosis International . Although there is evidence of higher incidences of fractures in patients with T1D compared with the general population, very little is known about the site-speci...

Lupin Recalls Irbesartan and Hydrochlorothiazide/Irbesartan Tablets

Oct 14th, 2021 - Lupin Pharmaceuticals is recalling all batches of irbesartan tablets USP 75 mg, 150 mg, and 300 mg and irbesartan and hydrochlorothiazide (HCTZ) tablets USP 150 mg/12.5 mg and 300 mg/12.5 mg because of the potential presence of the N-nitrosoirbesartan impurity. "As part of Lupin's ongoing assessment, analysis revealed that certain tested active pharmaceutical ingredient (API) batches (but not f...

Higher Risk of Chronic Disease in Trans vs Cisgender Individuals

Oct 13th, 2021 - A new study that looked at a large database of privately insured Americans has found that transgender individuals have a higher risk of chronic disease than their cisgender counterparts. Transgender people had higher rates of cardiovascular, neurologic, and endocrine conditions, mental health and substance use disorders, chronic pulmonary disease, anemia, liver disease, renal failure, rheumatoi...

Earlier-Life CAC Scans; Omega-3s and Afib; RV vs LV Abnormalities in COVID

Oct 12th, 2021 - Should some individuals at risk of atherosclerotic cardiovascular disease start getting coronary artery calcium scans in their mid-to-late 30s? (Journal of the American College of Cardiology) IV thrombolytics may be safe for stroke patients with unruptured intracranial aneurysms, a single-center study found. (Neurology) Major thromboembolism and death were less likely when hospitalized COVID-19...

Insulins: Out With the Old, In With the New

Oct 12th, 2021 - New insulin products were the go-to choice for U.S. adults with type 2 diabetes in the last half decade, researchers reported. According to a serial cross-sectional study of ambulatory insulin use over the past 5 years, newer insulin products FDA approved after 2010 were much more frequently used, accounting for 18.1% of total treatment visits in 2016 (1.1 million visits, 95% CI 0.8-1.4 million...

Overweight/Obesity Is Common in T1D and a Risk Factor for Double Diabetes

Oct 12th, 2021 - Takeaway Overweight/obesity was very common in patients with type 1 diabetes mellitus (T1DM) and was associated with double diabetes (DD). Body mass index (BMI) was positively associated with total daily insulin dose in patients with T1DM. DD was linked to an adverse cardiovascular risk profile and was common in lean patients with T1DM. Why this matters Findings warrant further research to dete...

Expensive Insulins, Pen Devices Dominate Diabetes Care in US

Oct 12th, 2021 - Despite the extensive recent focus on its cost, insulin use in the United States remains dominated by insulin glargine and other analogs, as well as pen devices for delivery, new research shows. The findings come from a nationally representative audit of outpatient care with input from nearly 5000 physicians who prescribed insulin to patients with type 2 diabetes in 2016-2020. The dramatic rise...

Synthetic Chemical in Consumer Products Linked to Early Death, Study Says

Oct 12th, 2021 - Daily exposure to phthalates, which are synthetic chemicals founds in many consumer products, may lead to hundreds of thousands of early deaths each year among older adults in the U.S., according to a new study published Tuesday in the peer-reviewed journal Environmental Pollution. The chemicals are found in hundreds of types of products, including children's toys, food storage containers, make...