About 527,200 results

Clinical Edge Journal Scan Commentary: Multiple Sclerosis June 2022
Mark Gudesblatt, MD

May 27th, 2022 - Mark Gudesblatt, MD Multiple sclerosis (MS) remains a complex disease with varied effects, some visible and clinically symptomatic and others invisible (eg, effects on cognition). However much we focus on the visible and uncovering the currently invisible effects, we must be aware of the effects of prior infection with SARS-CoV-2 (ie, post-acute COVID-19 syndrome, aka long COVID) in people with.

Psychological intervention looks promising in Crohn’s disease
Laird Harrison

May 27th, 2022 - SAN DIEGO – A combination of cognitive-behavioral therapy and mindfulness meditation could reduce pain and fatigue from Crohn’s disease, researchers say. Patients who followed the program not only felt better but were also more often able to show up for work and leisure activities, compared with a control group assigned to a wait list, said Shmuel Odes, MD, a professor of internal medicine at B.

Race-, ethnicity-based clinical guidelines miss the mark: Study
Jim Kling

May 27th, 2022 - SAN DIEGO – Race-based recommendations and clinical algorithms may be doing more harm than good, according to a systematic review of databases and guidelines. The study found examples of screening recommendations based on race or ethnicity that were likely misleading since these are social constructs that don’t reflect a patient’s individual risk, said Shazia Siddique, MD, who presented the stu.

Does taking isotretinoin worsen a patient’s baseline IBD symptoms?
Doug Brunk

May 27th, 2022 - A limited association exists between the use of isotretinoin for severe acne and worsening of a patient’s baseline inflammatory bowel disease, results from a small retrospective study suggests. “Early studies of isotretinoin for use in severe acne suggested the drug may serve as a trigger for new-onset inflammatory bowel disease (IBD),” researchers led by Christina G.

Urinating multiple times per night

May 27th, 2022 - On the basis of the patient's history and presentation, this is likely a case of adenocarcinoma of the prostate. Although most patients with prostate cancer are diagnosed on screening, when localized symptoms do occur, they may include urinary frequency, decreased urine stream, urinary urgency, and hematuria.

Rapid Review Quiz: Nonalcoholic Fatty Liver Disease (NAFLD)

May 27th, 2022 - Approximately 25% of the global population has nonalcoholic fatty liver disease (NAFLD), a broad term that covers a range of conditions. NAFLD is defined by the presence of macrovesicular steatosis without secondary causes, such as chronic use of medications, significant alcohol consumption, or hereditary disorders. Several phases of progression are noted, including simple steatosis, fibrosis, ...

COVID-19 Vaccines Work Better and for Longer Than Expected Across Populations, Including Immunocompromised Individuals

May 27th, 2022 - The mRNA vaccines are powerful in terms of preventing severe disease with COVID-19 across populations because of the multifaceted immune response they generate, a redundancy that can help among patients on agents which cause immunocompromise. Although antibodies from the vaccines will wane over time, or these antibodies can be less effective against new variants like Omicron, the vaccines do no...

Update on Rabies, TBE, and Cholera Vaccines Before Travel

May 27th, 2022 - Healthcare providers should be aware of important updates to vaccine recommendations that could affect patients preparing to travel internationally this summer. This includes information about: New rabies pre-exposure prophylaxis guidelines (PrEP); The new tick-borne encephalitis (TBE) vaccine; and Updated cholera vaccine recommendations and a restart of Vaxchora manufacturing and distribution....

UCLA Reinstates Mask Mandate as California COVID Cases Surge

May 27th, 2022 - Editor's note: Find the latest COVID-19 news and guidance in Medscape's Coronavirus Resource Center. LOS ANGELES (AP) — The University of California, Los Angeles said Thursday it will reinstate an indoor mask policy as coronavirus cases surge in the nation's most populous state, which now forecasts hospitalizations will nearly triple in the next month. UCLA's 45,000 students and all faculty, st...

Baby Formula Shortage Highlights Racial Disparities

May 27th, 2022 - COLUMBIA, Md. (AP) — Capri Isidoro broke down in tears in the office of a lactation consultant. The mother of two had been struggling to breastfeed her 1-month-old daughter ever since she was born, when the hospital gave the baby formula first without consulting her on her desire to breastfeed. Now, with massive safety recall and supply disruptions causing formula shortages across the United St...

Gout App Improves Treat to Target, Reduces Flares

May 27th, 2022 - Self-management of gout using a smartphone app to record self-test urate levels and flares, and communicate those results to clinicians, could see more patients reaching target urate levels and even reducing flare frequency, a study has found. Writing in The Lancet Rheumatology, Philip Riches, PhD, of the rheumatic disease unit at Western General Hospital in Edinburgh, and coauthors presented t...

Study Addresses Whether Isotretinoin Precipitates IBD Flares

May 27th, 2022 - A limited association exists between the use of isotretinoin for severe acne and worsening of a patient's baseline inflammatory bowel disease, results from a small retrospective study suggests. "Early studies of isotretinoin for use in severe acne suggested the drug may serve as a trigger for new-onset inflammatory bowel disease (IBD)," researchers led by Christina G. Lopez, MD, of the Lewis Ka...

Overlooked: Black Woman Doctor's Key Role in Oncology History 

May 27th, 2022 - When Jane Cooke Wright, MD, entered the medical profession in 1945, the notion that toxic drugs could target tumors struck many physicians and patients as outlandish. How could one poison be weaponized against another poison — a cancerous tumor — without creating more havoc? Let alone a combination of two or more chemicals? Yet by the time Wright retired in 1987, chemotherapy treatments that sh...

Screening Finds Albuminuria in 3% of Community Adults

May 27th, 2022 - Roughly 3% of adults in the general population of The Netherlands have microalbuminuria or macroalbuminuria, and in nearly two thirds of this subgroup — roughly 2% of the general population — kidney disease had previously gone unidentified, based on screening results in a study of about 15,000 adults. "This is the first study to prospectively investigate population screening for albuminuria," s...

Betting on 'Golden Age' of Colonoscopies, Private Equity Invests in Gastro Docs

May 27th, 2022 - Mariel needed a new gastroenterologist. Having just moved back to San Antonio, the 30-something searched for a doctor to manage her Crohn's disease, an inflammatory bowel condition that is successfully managed with medications and lifelong monitoring — including regular colonoscopies. Mariel booked an appointment and learned she would be on the hook for a $1,100 colonoscopy — about three times ...

FDA Okays IN.PACT 018 Drug-Coated Balloon for PAD

May 27th, 2022 - The US Food and Drug Administration has approved the IN.PACT 018 drug-coated balloon (DCB) for the treatment of peripheral arterial disease, Medtronic announced today. The paclitaxel-coated balloon is indicated for percutaneous transluminal angioplasty of de novo, restenotic, or in-stent restenotic lesions up to 360 mm in length with vessel diameters of 4 to 7 mm, located in the superficial fem...

Artificial Insemination Births Ebb in Women With Underweight

May 27th, 2022 - Researchers published the study covered in this summary on researchsquare.com as a preprint that has not yet been peer reviewed. Key Takeaways In a large cohort of women with a body mass index (BMI) below 30 kg/m2 receiving up to four intrauterine insemination (IUI) infertility treatments in China, those with underweight were significantly less likely to become pregnant or have a live birth, wh...

ESG's Cardiometabolic Benefits Last 5 Years

May 27th, 2022 - SAN DIEGO – Endoscopic sleeve gastroplasty (ESG) led to sustained weight loss and a reduction of cardiometabolic syndrome comorbidities at 5 years, according to a new retrospective analysis of prospectively collected data. Dr Donevan Westerveld Improved cardiometabolic outcomes following bariatric surgery have been well documented, but ESG is relatively new, so its outcomes haven't been as well...

Number of US Monkeypox Cases Grows to 10, CDC Says

May 27th, 2022 - Ten monkeypox cases have been identified in eight states, according to the CDC. The CDC website said that as of 5 p.m. Thursday, health officials had identified two cases in Florida, two cases in Utah, and one case each in California, Colorado, Massachusetts, New York, Virginia, and Washington state. CDC Director Rochelle Walensky, MD, said Thursday that most of the cases "are within gay [and] ...

H pylori Antibiotics Briefly Disrupt Gut Microbiome

May 27th, 2022 - SAN DIEGO – Treatments to eradicate Helicobacter pylori (H. pylori) infections do increase the antibiotic resistance of the gut microbiota, but for only a few months, researchers reported at Digestive Disease Week® (DDW). The finding applies similarly to levofloxacin quadruple therapy and bismuth quadruple therapy, both of which are equally efficacious as second-line treatments, said Jyh-Ming L...