Oct 25th, 2021 - A newly updated version of the Model for End-Stage Liver Disease (MELD) score was effective for predicting short-term mortality in patients with end-stage liver disease and addressed important determinants of wait list outcomes that haven’t been addressed in previous versions, according to findings from a recent study. The new model, termed MELD 3.
Anna Kim, MD, Jiehyun Jeon, MD, PhD et. al.
Oct 25th, 2021 - To the Editor: Lymphangioma circumscriptum (LC) is a benign malformation of the lymphatic system. 1 It is postulated to arise from abnormal lymphatic cisterns, and it grows separately from the normal lymphatic system.
Victor A. Teran, MD, Katherine G. Belote, MD et. al.
Oct 25th, 2021 - Cutaneous granulomatous diseases encompass many entities that are skin-limited or systemic. The prototypical cutaneous granuloma is a painless, rounded, well-defined, red-pink or flesh-colored papule1 and is smooth, owing to minimal epidermal involvement.
Oct 25th, 2021 - Note that some links may require registration or subscription. NIH officials admitted that they funded research to the Wuhan Institute of Virology that enhanced bat coronaviruses, but insisted there were too many genetic differences for one of those viruses to have led to the origin of the COVID pandemic. (Vanity Fair) Meanwhile, 24 legislators sent a letter to NIAID Director Anthony Fauci, MD,...
Oct 25th, 2021 - Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the cause of the ongoing coronavirus disease (COVID-19) pandemic, causes high rates of illness and death among humans. SARS-CoV-2 is a newly recognized member of the genus Betacoronavirus, family Coronaviridae, that infects humans. An early serosurvey among domestic cats in Wuhan, China, during January–March 2020 reported 14.7% serop...
Oct 25th, 2021 - Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has rapidly spread globally since its emergence in December 2019. As of March 2021, >120 million infections have been reported, and >2.7 million deaths have been attributed to the novel coronavirus disease (COVID-19) (1). The severity of COVID-19 and the risk for a complicated course of illness or death increase with age (2,3). In ter...
Oct 25th, 2021 - Burkholderia pseudomallei, an environmental gram-negative bacterium, causes the disease melioidosis. Although infection is frequently asymptomatic, melioidosis may be rapidly fatal for patients with underlying conditions that increase the risk for invasive disease. Modeling suggests that B. pseudomallei is ubiquitous in the tropics and that the global burden of disease is expected to rise (1). ...
Oct 24th, 2021 - Key clinical point: Patients with psoriasis with the most severe disease were at highest risk of developing psoriatic arthritis (PsA), highlighting the need for regular screening for signs and symptoms of PsA. Major finding: Overall incidence of PsA in patients with mild, moderate, and severe psoriasis was 2.
Oct 24th, 2021 - Key clinical point: Evaluation with power Doppler ultrasound revealed a rapid and significant reduction of synovitis in patients with psoriatic arthritis (PsA) upon treatment with secukinumab. Major finding : At week 12, the adjusted mean change in the global European League Against Rheumatism (EULAR) and the Outcome Measures in Rheumatoid Arthritis Clinical Trials (OMERACT) (EULAR-OMERACT) syn.
Oct 24th, 2021 - Key clinical point: Risk classification at acute myeloid leukemia (AML) diagnosis predicted clinical outcomes in patients with or without KMT2A-rearranged AML who underwent allogeneic hematopoietic cell transplant (HCT) in the first complete remission (CR1). Major finding: Transplanted patients with KMT2A-rearranged and adverse-risk AML had worse overall survival (hazard ratio [HR] 1.
Oct 24th, 2021 - Key clinical point: Treatment with nonsteroidal anti-inflammatory drugs (NSAID) worsened exocrine pancreatic insufficiency (EPI) in patients with primary osteoarthritis in gastrointestinal comorbidity with EPI. Moreover, the trophologic status of patients also deteriorated, indicating reduced nutrient uptake because of aggravation of EPI.
Oct 24th, 2021 - Key clinical point: After adjustment for hyperlipidemia, the risk of developing rheumatoid arthritis (RA) was not higher among statin users than nonusers. Major finding: After adjusting for hyperlipidemia, the risk of developing RA was not higher among former users of statins (adjusted odds ratio [aOR] 1.
I’ve been at CDC since 2006. I’m a Captain in the United States Public Health Service, a veterinarian, and an epidemiologist. So why is a veterinarian working for a human health agency? That’s because of One Health, the close connection between human health, animal health, and the health of our shared environment. People, animals, and the environment face many of the same health challenges, so ...
I joined CDC in 2010, after working for the Connecticut Department of Public Health, because I wanted to protect people’s health in the whole country, not just in one state. Currently, I work for the National Center for Immunization and Respiratory Diseases. We assess child and adult vaccination coverage in the United States. Vaccinations are one of the top ten great public health achievements ...
I work for the Division of Global Migration and Quarantine as the Officer-in-Charge of the CDC Atlanta Quarantine Station at Hartsfield Jackson Atlanta International Airport, the world’s busiest airport. I’m a public health first responder, leading and coordinating activities that prevent the introduction and spread of communicable diseases into the U.S., 24/7. We respond to illnesses and death...
Oct 24th, 2021 - SCOTTSDALE, Ariz. -- Having COVID-19 was tied to a somewhat increased risk of a new erectile dysfunction (ED) diagnosis, a researcher reported here. Data from the study came from a U.S. insurance database and, after propensity matching, 230,517 men with recorded COVID-19 were identified, as were 232,645 without recorded COVID-19. After controlling for various factors, infection with SARS-CoV-2 ...
Oct 24th, 2021 - If pushed through, the Treat and Reduce Obesity Act would expand access to obesity treatment, using Medicare Part D to cover anti-obesity medication and behavioral therapy. (The Hill) One way to potentially help thwart excess weight in infants: a good night's sleep. "In this study, we found that not only shorter nighttime sleep, but more sleep awakenings, were associated with a higher likelihoo...
Oct 23rd, 2021 - The FDA has approved a first-of-its kind continuous delivery system for anti-VEGF therapy for neovascular (wet) age-related macular degeneration (AMD). The Susvimo ocular implant continuously releases 100 mg/mL of ranibizumab directly to the retina over 6 months. Initial implantation and refill can be performed during an office visit with an ophthalmologist. In contrast, conventional intravitre...
Oct 22nd, 2021 - Approximately 20% of pediatric patients with cancer infected with COVID-19 experienced severe illness, according to data published in The Lancet Oncology. Furthermore, deaths due to the infection were proportionally higher in this patient population compared with the general pediatric population, providing evidence that children with cancer are at higher risk of developing severe illness from C...
Oct 22nd, 2021 - The National Institutes of Health (NIH) has awarded a grant to fund cellular senescence research in lymphoid organs at Yale Cancer Center. The five-year, $6.5 million grant will help generate multiscale molecular and cellular maps of cellular senescence in primary and secondary human lymphoid organs to improve our understanding of cellular senescence in development, aging, and disease, includin...