About 377,090 results

Ibrutinib Increases Risk of Select Cardiovascular AEs in Patients With Chronic Lymphocytic Leukemia

Jan 14th, 2022 - Treatment with ibrutinib (Imbruvica) in patients with chronic lymphocytic leukemia (CLL) was linked with increased risk of cardiovascular adverse effects (AEs) like atrial fibrillation (AF), hospital-diagnosed bleeding, and heart failure (HF), but was not linked with a higher risk of acute myocardial infarction (AMI) or stroke, according to population-level data from a report published in the J...

Nivolumab Continues to Elicit Durable Responses in Advanced Hepatocellular Carcinoma

Jan 14th, 2022 - Nivolumab (Opdivo) elicited a prolonged clinical benefit in patients with advanced hepatocellular carcinoma (HCC) regardless of prior sorafenib (Nexavar) according to 5-year follow-up data from 2 cohorts of the phase 1/2 CheckMate040 trial (NCT01658878). Patients were stratified into cohorts based on prior sorafenib exposure and were enrolled regardless of HCC etiology and PD-L1 expression s...

Medicaid expansion curbs disparities, increases immigrant access, in postpartum care
Roxanne Nelson, Marcia Frellick

Jan 14th, 2022 - Expanding Medicaid coverage has proved beneficial to postpartum women and may even help reduce disparities, say two new papers. In the first study, expansion of Medicaid coverage under the Affordable Care Act was associated with higher rates of postpartum coverage and outpatient visits, according to results published in JAMA Health Forum.

Immunotherapy Outcomes in HPV-Associated Head and Neck Cancer Fuel Investigative Efforts

Jan 14th, 2022 - Promising data from studies evaluating immunotherapy and cellular therapy for patients with head and neck cancers associated with human papilloma virus (HPV) have helped to widen the treatment landscape. However, many clinical questions remain unanswered as to the appropriate sequencing for the trials. Additionally, investigators have looked to the success in this patient population to develop ...

Optimized Treatment Starts With Molecular Testing in NSCLC

Jan 14th, 2022 - Although survival data from the large, phase 3 ADAURA (NCT02511106)and CROWN (NCT03052608) trials are still anticipated in advanced non–small cell lung cancer (NSCLC), molecular testing should not be withheld from patients with non–small cell lung cancer (NSCLC) in the interim, according to Konstantinos Arnaoutakis, MD, who added that the primary results from both studies warrant discussion wit...

Future Outlook of EGFR Mutant NSCLC

Jan 14th, 2022 - Solange Peters, MD, PhD: In advanced stage EGFR-mutating non-small cell lung cancer, we are waiting for data to offer options, specifically targeted and personalized options for resistance. This is moving with, for example, the ADAURA trial, but there are others. Once you manage to establish what the mechanism of resistance is, then what are the subsequent options, still excluding chemotherapy?...

Brain Injury Biomarkers Elevated in Hospitalized COVID Patients

Jan 14th, 2022 - Hospitalized patients with COVID-19 and no prior history of dementia had elevated levels of brain injury biomarkers, an observational study showed. Blood levels of total tau (t-tau), phosphorylated tau181 (p-tau181), glial fibrillary acidic protein (GFAP), and neurofilament light (NfL) were significantly elevated in COVID-19 patients with encephalopathy and those who died in the hospital, repor...

Private insurers must cover follow-up colonoscopies
Heidi Splete

Jan 14th, 2022 - Private insurers are now required to cover the cost of follow-up colonoscopies after a positive stool-based test, according to updated guidance from the Biden administration cited in a press release from the American Gastroenterological Association. “Now patients can choose the best colorectal cancer screening test for them without fear of a surprise bill.

Pricier Diabetes Care for Low-Income Patients With Marketplace Insurance?

Jan 14th, 2022 - For Coloradans with diabetes and lower incomes, those eligible for Medicaid saw better antidiabetic agent access than those covered by one of the state's subsidized Marketplace insurance plans, a new study found. Looking at nearly 23,000 patients with diabetes living in the state, those on Medicaid had both higher prescription drug utilization and lower drug costs compared with individuals enro...

3D Virtual Reality Poised to Offer Superior Patient Education in Oncology

Jan 14th, 2022 - Patient education in oncology can often be daunting and complicated for clinicians and patients. Traditional patient education methods such as videos, handouts, and reviewing standard medical imaging often fall short in conveying complex information. As a result, 3-dimensional (3D) virtual reality (VR) experiences are increasingly being explored as an appealing alternative method of imaging rev...

Study: Safe Injection Site Reduces ED Use, Hospitalization

Jan 14th, 2022 - People using an unsanctioned safe consumption site (SCS) for injection drug use had a reduced chance of emergency department (ED) visits and hospitalization, researchers found. According to a study in the Journal of General Internal Medicine, at one unsanctioned SCS -- which quietly opened in an undisclosed urban neighborhood in 2014 -- facility users had: During each 6-month period, those who ...

Blood Supply Crisis Worsens; Gene Doubles Severe COVID Risk; 1M Tests Made Unexpired

Jan 14th, 2022 - Note that some links may require registration or subscription. A nationwide blood supply crisis is forcing hospitals, doctors, and patients to make difficult decisions. (NPR) More than two dozen members of Congress have joined LGBTQ advocates in urging the FDA to rescind its 3-month celibacy requirement for gay and bisexual men prior to donating blood. (NBC News) Polish scientists have found a ...

Fast Five Quiz: Overview of Acute Pain Management

Jan 14th, 2022 - Acute pain is a sudden physiologic response to noxious stimuli. Individuals may experience acute pain after a burn or trauma, or following surgery in the perioperative period. Patients with chronic illnesses (eg, arthritis, neuropathies, spinal conditions, low back pain, multiple sclerosis, sickle cell disease, migraine, trigeminal pain or neuralgia, complex pain syndrome) may also experience a...

Fast Five Quiz: Overview of Acute Pain Management

Jan 14th, 2022 - Acute pain is a sudden physiologic response to noxious stimuli. Individuals may experience acute pain after a burn or trauma, or following surgery in the perioperative period. Patients with chronic illnesses (eg, arthritis, neuropathies, spinal conditions, low back pain, multiple sclerosis, sickle cell disease, migraine, trigeminal pain or neuralgia, complex pain syndrome) may also experience a...

I Took COVID Precautions and Still Got a Breakthrough Infection

Jan 14th, 2022 - I have a breakthrough COVID infection. With the Omicron variant spreading globally, cases are rising again and I know I'm not alone. My case is mild, but it is evidence of just how vulnerable we still are in this pandemic. I live in New York. When the travel ban lifted in November, my mother came to visit and wanted to see the city. My mother is fully vaccinated and boosted, I am fully vaccinat...

Diverse Needs of Post-COVID-19 Patients Managed In or Out of Hospital

Jan 14th, 2022 - NEW YORK (Reuters Health) - A large study from the UK shows that patients who recover from COVID-19, whether managed in or outside the hospital, often seek care from their primary-care provider for multiple lingering problems - and those problems may differ between the two groups. The study provides "invaluable insights" into the healthcare-seeking behaviors of patients after COVID-19 and sugge...

Radiation Oncology: More Women Now, but Numbers Still Low

Jan 14th, 2022 - Over the past two decades, more of the senior positions with radiation oncology (such as associate or full professors) have been filled by women, but there are still very few minorities in these positions. Nevertheless, compared to other specialties, "radiation oncology has some of the lowest numbers" for female minority senior faculty, say the authors of a new analysis. The findings come from ...

Disparities in GLP-1 Receptor Agonist Use in Type 2 Diabetes

Jan 14th, 2022 - (Reuters Health) - White and more affluent patients with type 2 diabetes are significantly more likely to receive glucagon-like peptide-1 (GLP-1) receptor agonist therapy than individuals who are Black, Asian, Hispanic or low-income, a U.S. study suggests. Researchers examined commercial health insurance claims data collected from October 2015 to June 2019 on 1.18 million U.S. patients with typ...

Sir Jonathan Van-Tam Resigns as England's Deputy Chief Medical Officer

Jan 14th, 2022 - Prof Sir Jonathan Van-Tam is leaving his post as deputy chief medical officer (DCMO) for England to return to the University of Nottingham to take up a new role. Prime Minister Boris Johnson thanked him for his "extraordinary contribution" during the COVID-19 crisis. Prof Van-Tam became a well-known face on TV for his liberal sprinkling of analogies to deliver urgent public health messages in a...

Reduced Isolation Period Gets Mixed Welcome

Jan 14th, 2022 - Editor's note: This article has been updated with additional comments The Government has announced that from Monday 17 January, self-isolation for those testing positive for COVID-19 can end after 5 full days, provided they test negative on days 5 and 6 and do not have a raised temperature. People whose rapid lateral flow tests remain positive must stay in isolation until they have had two cons...