Apr 29th, 2021 - Federal advisers this week supported the efforts of pharmaceutical companies in 4 of 6 cases in which these firms are fighting to maintain cancer indications for approved drugs. They voted against them in two cases. The staff of the US Food and Drug Administration (FDA) will now consider these votes as they decide what to do regarding the six cases of what they have termed "dangling" accelerate...

Jul 25th, 2019 - For the first time, a pediatric cancer has been added to the "BRCA2 family." Researchers at St. Jude Children's Research Hospital in Memphis, Tennessee, revealed that BRCA2 mutations were five times more common in children with non-Hodgkin lymphoma compared to a control group. The study was published online on July 25 in JAMA Oncology. Although this may seem like bad news, in fact it provides m...

Oct 11th, 2017 - Is it worthwhile for patients with pancreatic cancer to seek care at a high-volume institution? The authors of a study published in Annals of Surgery[1] analyzed this problem using data from patients (N = 7086) obtained from 1998 to 2012 from the National Cancer Database. The main analysis was restricted to patients undergoing a pancreaticoduodenectomy at either a local facility performing fewe...

May 30th, 2017 - New Insights: Psoriasis, Cardiovascular Risk, and Metabolic Syndrome In regard to cardiovascular risk, on the basis of epidemiologic study, it appears that people with more severe psoriasis experience increased risk for stroke, myocardial infarction, and death secondary to cardiovascular causes independent of conventional risk factors. Such epidemiologic study as well as an improved understandi...

May 30th, 2017 - Background The medical community has been familiar with psoriasis for over 2000 years. Hippocrates, who lived between 460 and 377 BC, described what appears to be psoriasis in the Hippocratic Corpus. Specifically, Hippocrates used the term psora ("itch") to describe the condition.[1] Although psoriasis has been treated for eons, understanding of the disease has rapidly grown in recent years. Th...

May 30th, 2017 - Background The medical community has been familiar with psoriasis for over 2000 years. Hippocrates, who lived between 460 and 377 BC, described what appears to be psoriasis in the Hippocratic Corpus. Specifically, Hippocrates used the term psora ("itch") to describe the condition.[1] Although psoriasis has been treated for eons, understanding of the disease has rapidly grown in recent years. Th...

May 30th, 2017 - Background The medical community has been familiar with psoriasis for over 2000 years. Hippocrates, who lived between 460 and 377 BC, described what appears to be psoriasis in the Hippocratic Corpus. Specifically, Hippocrates used the term psora ("itch") to describe the condition.[1] Although psoriasis has been treated for eons, understanding of the disease has rapidly grown in recent years. Th...

Dec 2nd, 2015 - There is huge variation in the price of cancer drugs in high-income countries, with some countries charged more than double the price others are expected to pay, the results of an international survey reveal. The research, which was published online December 3 by Lancet Oncology, shows that the differences in the prices of novel cancer drugs between European countries and Australia and New Zeal...

Feb 4th, 2014 - Racial and Socioeconomic Disparities in Presentation and Outcomes of Well-Differentiated Thyroid Cancer Harari A, Li N, Yeh MW J Clin Endocrinol Metab. 2014;99:133-141 Article Summary Thyroid cancer is common and is increasing in frequency at an alarming rate. The purpose of this study was to assess disparities in the outcomes of thyroid cancer patients on the basis of racial and socioeconomic ...

Abstract and Introduction Abstract Background: Anti-PD1/PD-L1 directed immune checkpoint inhibitors (ICI) are widely used to treat patients with advanced non-small-cell lung cancer (NSCLC). The activity of ICI across NSCLC harboring oncogenic alterations is poorly characterized. The aim of our study was to address the efficacy of ICI in the context of oncogenic addiction. Patients and methods: ...

For the first time, a pediatric cancer has been added to the "BRCA2 family." Researchers at St. Jude Children's Research Hospital in Memphis, Tennessee, revealed that BRCA2 mutations were five times more common in children with non-Hodgkin lymphoma compared to a control group. The study was published online on July 25 in JAMA Oncology. Although this may seem like bad news, in fact it provides m...

Background The medical community has been familiar with psoriasis for over 2000 years. Hippocrates, who lived between 460 and 377 BC, described what appears to be psoriasis in the Hippocratic Corpus. Specifically, Hippocrates used the term psora ("itch") to describe the condition.[1] Although psoriasis has been treated for eons, understanding of the disease has rapidly grown in recent years. Th...

There is huge variation in the price of cancer drugs in high-income countries, with some countries charged more than double the price others are expected to pay, the results of an international survey reveal. The research, which was published online December 3 by Lancet Oncology, shows that the differences in the prices of novel cancer drugs between European countries and Australia and New Zeal...

Is it worthwhile for patients with pancreatic cancer to seek care at a high-volume institution? The authors of a study published in Annals of Surgery[1] analyzed this problem using data from patients (N = 7086) obtained from 1998 to 2012 from the National Cancer Database. The main analysis was restricted to patients undergoing a pancreaticoduodenectomy at either a local facility performing fewe...