About 59,750 results

Acute hepatic porphyrias no longer as rare as previously thought
Carolyn Crist

Jan 30th, 2023 - Although rare, acute hepatic porphyrias (AHPs) may be more common than previously thought, particularly among women between ages 15 and 50, according to a new clinical practice update from the American Gastroenterological Association. For acute attacks, treatment should include intravenous hemin, and for patients with recurrent attacks, a newly-approved therapy called givosiran should be consid.

Study: Diminished COVID Vaccine Response in Lupus

Jan 30th, 2023 - Patients with systemic lupus erythematosus (SLE) showed reduced antibody responses following COVID-19 vaccination, with drugs for the condition such as belimumab (Benlysta) and mycophenolate mofetil (MMF) likely to blame, researchers said. Immunoglobulin G (IgG) titers measured 2 weeks after the second dose of mRNA COVID vaccines were lower by about 20% among 342 lupus patients compared with th...

How Racial and Ethnic Disparities in Alzheimer Disease Affect Diagnosis, Quality of Care
Clinical Advisor

Jan 27th, 2023 - As researchers continue to seek insights to improve the understanding, prevention, and treatment of Alzheimer disease and related dementias (ADRD), a growing body of research highlights significant racial and ethnic disparities in various aspects of these diseases.1 “In Blacks and Hispanics, the prevalence of ADRD is 1.5 to 2 times higher compared to non-Hispanic Whites,” said Timothy S. Chang,...

PsA-related uveitis: Real-world data on epidemiology and clinical features

Jan 26th, 2023 - Key clinical point: Uveitis related to psoriatic arthritis (PsA) had a prevalence of approximately 5%, presented as an acute and recurrent disease with anterior and unilateral involvement, and was associated with impaired quality of life and increased functional disability. Major finding: Uveitis onset was acute in all cases, with 50% being recurrent and 80% being anterior and unilateral.

Preventing Bedsores in Nursing Home Patients
Clinical Advisor

Jan 25th, 2023 - Every month, the leadership team at the Gerontological Advanced Practice Nurses Association (GAPNA) highlights the most important published literature that impacts geriatric practice. This month, Valerie K. Sabol, PhD, MBA, ACNP, GNP, ANEF, FAANP, FAAN, past president of GAPNA, explores the theme of pressure injury prevention in nursing home patients. She comments on 3 recent studies on prevent...

Expanding the national dialogue on healthcare to include the intersection of structural racism and ageism

Jan 24th, 2023 - INDIANAPOLIS -- Regenstrief Institute Research Scientist Kathleen Unroe, M.D., MHA, is a co-author of a position paper from the American Geriatrics Society delving into the intersection of structural racism and ageism in healthcare. The paper presents a framework to describe these concepts whose negative effects on health outcomes can be amplified when they intersect. The goal of the position p...

Study shows impact of vitamin D, thyroid hormones on child development

Jan 24th, 2023 - HUNTINGTON, W.Va. – Prenatal exposure to altered levels of vitamin D and/or thyroid hormones has the potential to impact child development long after birth, according to a new study by researchers at the Marshall University Joan C. Edwards School of Medicine. A retrospective study analyzed the presence of 20 different elements, thyroid hormones and vitamin D levels in umbilical cord blood colle...

Development of a Safety Awards Program at a Veterans Affairs Health Care System: A Quality Improvement Initiative
Naseema B. Merchant, MD, Jessica O’Neal, MSHA et. al.

Jan 23rd, 2023 - ABSTRACT Objective: Promoting a culture of safety is a critical component of improving health care quality. Recognizing staff who stop the line for safety can positively impact the growth of a culture of safety.

In Knee OA, Exercise Is Helpful ... But Maybe More in Mind Than Body

Jan 23rd, 2023 - High-dose exercise was only slightly more beneficial for patients with knee osteoarthritis (OA) than a less-intense program in a randomized trial, researchers said. After 12 weeks of program participation, mean Knee Injury and Osteoarthritis Outcome Score (KOOS) ratings for pain, daily function, and quality of life improved with both regimens, but with no significant differences between them, a...

ACP Guideline Backs Newer Antidepressants, CBT for Acute Phase of Major Depression

Jan 23rd, 2023 - Cognitive behavioral therapy (CBT), second-generation antidepressants, or a combination of the two approaches are recommended for the initial treatment of adults in the acute phase of moderate-to-severe major depressive disorder (MDD), according to updated clinical recommendations from the American College of Physicians (ACP). The decision on which treatment to start first should be based on a ...

Teamwork guides cardio-rheumatology clinics that care for unique patient population
Jennifer Lubell

Jan 23rd, 2023 - Clinical cardiologist Heba Wassif, MD, MPH, knows the value of working with her fellow rheumatologists, surgeons, and other clinicians to establish a care plan for her patients with cardiac conditions and autoimmune diseases. She is the cofounder of the Cleveland Clinic’s new cardio-rheumatology program, which places an emphasis on multidisciplinary care.

American College of Physicians recommends cognitive behavioral therapy or second-generation antidepressants for adults with major depressive disorder

Jan 23rd, 2023 - 1. American College of Physicians recommends cognitive behavioral therapy or second-generation antidepressants for adults with major depressive disorder  Doctors and Patients should discuss treatment benefits, harms, adverse effect profiles, costs, accessibility, and patient preferences when selecting a first-line and second-line treatment Guideline: https://www.acpjournals.org/doi/10.7326/M22-...

Moffitt researchers develop tool to measure patient health and well-being after radionuclide therapy

Jan 19th, 2023 - TAMPA, Fla. — Cancer is a devasting disease that significantly affects a patient’s daily quality of life and well-being. Health care providers are increasingly aware that the everyday struggles that cancer patients must endure can negatively impact long-term survival. As a result, providers now recognize the importance of measuring patient-reported outcomes by asking directly about patient heal...

Many older adults declined home medical care for fear of COVID, causing new or worsening conditions

Jan 18th, 2023 - COVID-19 interrupted or delayed medical treatment for many people who chose to put off elective procedures or couldn't get in to see a specialist. But new research from the University of Michigan finds another population was affected: Many homebound older adults canceled medically necessary home-based health care services out of fear of getting COVID-19. This caused new or worsening medical co...

New initiative provides biomedical research experience to West Virginia high school students

Jan 18th, 2023 - HUNTINGTON, W.Va. – A new initiative at the Marshall University Joan C. Edwards School of Medicine offers West Virginia high school students an opportunity to explore the field of biomedical research while working to facilitate a more diverse research workforce across Appalachia. As part of the Health Care Pathways Initiative (HCPI), a four-week summer residential experience at Marshall Univers...

COVID is changing how we are exposed to household health risks

Jan 17th, 2023 - COVID-19 is changing household behaviors related to how we are exposed to various household chemicals linked to poor health outcomes. People surveyed earlier in the pandemic were using less personal care products but more household cleaners, eating less fast food and restaurant food but more ultra-processed food. These changes which occurred since the pandemic onset are also linked to pandemic-...

Study explores effects of dietary choline deficiency on neurologic and system-wide health

Jan 17th, 2023 - Choline, an essential nutrient produced in small amounts in the liver and found in foods including eggs, broccoli, beans, meat and poultry, is a vital ingredient for human health. A new study explores deficiency in dietary choline adversely affects the body and may be a missing piece in the puzzle of Alzheimer’s disease. It’s estimated that more than 90% of Americans are not meeting the recomme...

Lifestyle adjustments may reduce painful menstrual symptoms, study suggests

Jan 17th, 2023 - Tsukuba, Japan—Adverse menstruation-related symptoms are common during menstrual cycles, which occur about once a month in healthy women. Primary dysmenorrhea (PD) and premenstrual syndrome (PMS) are especially prevalent and problematic, causing cramps, body pain, and numerous other disruptive physical and emotional symptoms. Now, a systematic review and meta-analysis conducted in Japan has fou...

Reduced Medicare Cost-Sharing Yields Uneven Uptick in Access to Mental Heath Care

Jan 17th, 2023 - Changes to Medicare policy that lowered out-of-pocket costs for outpatient mental health and substance use disorder (MHSUD) care, to achieve parity with typical cost-sharing under Medicare, were associated with uneven improvements in the use of these services across racial and ethnic groups, a study suggested. Specifically, MHSUD specialist visits among white beneficiaries increased during the ...

In poor countries, livestock ownership can improve nutritional outcomes but also raise disease risks

Jan 16th, 2023 - New study finds that livestock keeping can both improve and worsen the health of under-five children and women of reproductive age in low- and lower-middle-income countries According to a recent systematic review, the relationship between livestock keeping and the health of under-five children and women of reproductive age in low- and lower-middle-income countries is complex. While livestock pr...