Jan 26th, 2023 - It did not take long after pregnancy for excess heart attacks and strokes to emerge in women with pre-eclampsia, according to national records from Denmark. Within 20 years of delivery, the cumulative incidence of acute myocardial infarction (MI) and ischemic stroke approached 2.0% in women who had a history of pre-eclampsia versus 1.2% who had no pre-eclampsia, reported Sara Hallum, MSc, a PhD...

Jan 25th, 2023 - Premature cardiovascular disease (CVD) was associated with accelerated decline in cognition and white matter health in midlife, a large prospective cohort study showed. On a composite cognitive score, those with CVD events before age 60 were more than three times as likely to drop by at least 1.5 standard deviation more than the race-specific average over 5 years (OR 3.07, 95% CI 1.65-5.71), Kr...

Jan 24th, 2023 - In the Atherosclerosis Risk in Communities cohort, people with carotid atherosclerosis in mid-life were more likely to have worse hearing decades later. (JAMA Otolaryngology-Head & Neck Surgery) Higher HDL cholesterol corresponded with a higher risk of fractures in individuals over age 70. (JAMA Cardiology) Regarding screening children for lipid disorders, the U.S. Preventive Services Task Forc...

Jan 17th, 2023 - Happier, more optimistic teens stood a better chance of good cardiometabolic health approaching middle age. (Journal of the American Heart Association) Black Americans did not lose weight or improve lipid levels after switching to vegan soul food, a randomized trial showed. (JAMA Network Open) Emotional eating, such as overeating when one is sad, was associated with arterial stiffness in a long...

Jan 13th, 2023 - To the Editor: Surgical wounds on the lower leg are challenging to manage because venous stasis, bacterial colonization, and high tension may contribute to protracted healing. Advances in technology led to the development of novel, polymer-based wound-healing modalities that hold promise for the management of these wounds.

Jan 13th, 2023 - Replacing dual-antiplatelet therapy (DAPT) with clopidogrel alone 1 month after percutaneous intervention (PCI) offers a lower risk of bleeding with comparable protection against cardiovascular events, according to two subgroup analyses of the Japanese STOPDAPT-2 and STOPDAPT-2 ACS trials. The objective of these two analyses was to evaluate whether there was a benefit-to-risk ratio advantage fo.

Jan 12th, 2023 - Tissue plasminogen activator (t-PA) has been the standard IV thrombolytic used in acute ischemic stroke treatment since its US Food and Drug Administration (FDA) approval in 1995. Trials have established this drug’s efficacy in the treatment of acute ischemic stroke and the appropriate patient population for therapy.

Jan 12th, 2023 - Each month, makes one new clinical feature available ahead of print. Don’t forget to take the poll. The results will be published in the next month’s issue. Approximately 151 million patients visited emergency departments (EDs) in 2019 and the most common complaint was abdominal pain, according to data from the National Hospital Ambulatory Medical Care Survey (NHAMCS).1 Even though acute pain i...

Jan 11th, 2023 - Studies have increasingly shown that short and excessively long sleep durations are linked to worse cardiovascular outcomes,1 and accumulating research has begun to shed light on the deleterious effects of other components of poor sleep patterns, such as nighttime waking and increased sleep latency. In light of these findings, the American Heart Association (AHA) has made sleep health 1 of the ...

Jan 10th, 2023 - High levels of triglyceride molecules in LDL cholesterol are “robustly” linked with an increased risk of atherosclerotic cardiovascular disease, according to a study that used two different methods in two separate cohorts from a large European population study plus a meta-analysis to verify the results. “There have been some studies in the past, as you can see from our meta-analysis, that found.

Jan 10th, 2023 - Myocarditis associated with mRNA COVID-19 vaccines may be related to circulating free spike antigen, according to a study of antibody profiling and T-cell responses to immunization. (Circulation) Buffalo Bills safety Damar Hamlin's cardiac arrest last week prompted increased interest in online CPR education and resources, the American Heart Association said. Both hypotension and hypertension we...

Jan 10th, 2023 - Osaka, Japan – Controlling your food intake can be even more difficult than you think. Osaka Metropolitan University scientists show that visual food cues can affect your eating behavior even when you are not aware of them. Their findings were published in PLOS ONE. Obesity is one of the major pathological conditions that constitute lifestyle-related diseases and is known to be associated with ...

Jan 8th, 2023 - In this exclusive video, Harlan Krumholz, MD, SM, director of the Center for Outcomes Research and Evaluation at Yale University and Yale New Haven Hospital in Connecticut, reflects on the on-field cardiac arrest of NFL safety Damar Hamlin and the lessons to learn from this dramatic event. Krumholz, a cardiologist, is also the Harold H. Hines, Jr. Professor of Medicine and a professor in the In...

Jan 4th, 2023 - All patients undergoing surgical procedures requiring anesthesia should be screened for cannabis use, according to released by the American Society of Regional Anesthesia and Pain Medicine (ASRA Pain Medicine). Regular cannabis use may worsen pain and nausea after surgery and increase the need for opioids, according to ASRA Pain Medicine. The guidelines were developed in response to the increas...

Jan 4th, 2023 - A fatal bleeding event in an Alzheimer's clinical trial participant may have been linked with the investigational anti-amyloid agent lecanemab, a case report suggested. However, drug trialists are not willing to assign blame yet, especially as lecanemab's fate hangs in a potential FDA approval for early Alzheimer's disease later this week. Information about the case initially surfaced just days...

Jan 3rd, 2023 - Surgical candidates undergoing anesthesia should be screened universally for cannabis use, new guidelines from the American Society of Regional Anesthesia and Pain Medicine (ASRA Pain Medicine) stated. Anesthesiologists should ask all patients about the type of cannabis product used, whether it was smoked or ingested, the amount used, how recently it was used, and the frequency of use, reported...

Jan 3rd, 2023 - One in four cardiologists around the world self-reported having a mental health condition such as alcohol or drug use disorder, psychological distress, or major psychiatric disorder. (Journal of the American College of Cardiology) A polygenic risk score for coronary artery disease helped reclassify people at borderline and intermediate clinical risk who may be candidates for primary prevention ...

Dec 27th, 2022 - More steps each day mean lower risk of cardiovascular disease for older adults, a meta-analysis affirmed. (Circulation) Coronary artery calcium scoring ruled out obstructive coronary disease with good accuracy in the early triage of patients with chest pain in a large cohort study. However, it did not perform as well in those under age 45. (Heart) For patients with acute myocardial infarction, ...

Dec 19th, 2022 - This patient was given a diagnosis of Peutz-Jeghers syndrome (PJS) based on the characteristic pigmented mucocutaneous macules and numerous polyps in her stomach and small bowel. PJS is an autosomal dominant syndrome characterized by mucocutaneous pigmentation, polyposis of the GI tract, and increased cancer risk.

Dec 19th, 2022 - In SPRINT, intensive systolic blood pressure lowering decreased natriuretic peptide levels but increased high-sensitivity cardiac troponin T (cTn). (Circulation) The medical community braces for harmful messaging about COVID-19 vaccines after Florida Surgeon General Joseph Ladapo, MD, PhD, announced plans for another study on their links to myocarditis. (Orlando Sentinel) As an alternative to h...