About 15,735 results

How to Improve Health Disparities in Acute Pain Management in Emergency Departments
Clinical Advisor

Jan 12th, 2023 - Each month, makes one new clinical feature available ahead of print. Don’t forget to take the poll. The results will be published in the next month’s issue. Approximately 151 million patients visited emergency departments (EDs) in 2019 and the most common complaint was abdominal pain, according to data from the National Hospital Ambulatory Medical Care Survey (NHAMCS).1 Even though acute pain i...

How to Improve Health Disparities in Acute Pain Management in Emergency Departments
Clinical Advisor

Jan 12th, 2023 - Discussion The current retrospective chart review found a significant difference in pain management between non-Hispanic/Latino White patients and racial/ethnic minority patients and women. Non-Hispanic/Latino White patients were more likely to receive opioids during their ED visit than non-Hispanic/Latino Black, Hispanic/Latino, Asian, or other racial/ethnic groups. Furthermore, women waited l...

ASRA Recommends Screening for Cannabis Use Before Surgery
Clinical Advisor

Jan 4th, 2023 - All patients undergoing surgical procedures requiring anesthesia should be screened for cannabis use, according to released by the American Society of Regional Anesthesia and Pain Medicine (ASRA Pain Medicine). Regular cannabis use may worsen pain and nausea after surgery and increase the need for opioids, according to ASRA Pain Medicine. The guidelines were developed in response to the increas...

Clinical Challenge: Ring Finger Pain
Clinical Advisor

Jan 4th, 2023 - Making the Diagnosis To accurately assess and diagnose this patient’s condition, the clinician needs to consider conditions that would cause finger pain without injury. Infectious conditions would be a consideration but in this case no visible paronychia is found and an abscess would typically present as a red, swollen, and/or warm finger. Rheumatologic conditions can cause finger pain, but rap...

Clinical Challenge: Ring Finger Pain
Clinical Advisor

Jan 4th, 2023 - History of Present Illness A patient in his mid-60s with a history of end-stage renal disease (ESRD) presents to the emergency department (ED) with a 4-day history of left ring finger pain and discoloration. The patient denies any fever, injury, or other complaint. Vital Signs and Physical Examination The patient’s vital signs in the ED are essentially normal. Physical examination is normal exc...

Adagrasib (Krazati) Approved for KRAS-Mutated NSCLC

Dec 13th, 2022 - The US Food and Drug Administration (FDA) has granted accelerated approval to adagrasib (Krazati) for use in adults with KRAS G12C-mutated locally advanced or metastatic non–small cell lung cancer (NSCLC) that has progressed on at least one prior systemic therapy. Suitability for this therapy is to be determined by an FDA-approved test. The agency also approved two companion diagnostics: Qiagen...

Placebo Effect a Major Driver of Pain Reduction in Cannabis Trials

Dec 9th, 2022 - A strong placebo response may be largely responsible for the significant pain reduction observed in clinical trials of cannabis-based therapies, results of a new meta-analysis suggest. Investigators found that while the effect size of cannabinoids on pain intensity was significant, the placebo effect was about the same. "The data from the present meta-analysis, including 1459 patients with clin...

Opioids for Pain Clinical Practice Guidelines (CDC, 2022)

Dec 8th, 2022 - Guidelines for prescribing opioids for adults with acute and chronic pain were published in November 2022 by the US Centers for Disease Control and Prevention (CDC) in the Morbidity and Mortality Weekly Report (MMWR).[1,2] Initiating opioids for pain Before initiating opioid therapy, clinicians should discuss with patients the realistic benefits and known risks of opioid therapy. Clinicians sho...

CDC: Mpox Vaccine Is Effective Regardless of Administration Route

Dec 8th, 2022 - Intradermal administration of the JYNNEOS mpox vaccine is as effective and safe as subcutaneous administration, according to new data released this week by the Centers for Disease Control and Prevention (CDC). Unvaccinated people were nearly 10 times as likely to be infected with the mpox virus compared with those who had completed the two-dose series of the vaccine, and the reporting rates for...

Tackling Oral Health in Primary Care: A Task That's Worth the Time

Dec 8th, 2022 - Tooth decay can be easy to overlook — particularly for pediatricians and family physicians, who may be neglecting a crucial aspect of childhood health. Left untreated, it can lead to serious and even fatal medical problems. The incorporation of preventive oral health care services like the application of fluoride varnish into primary care may be helping protect kids' smiles and improving their ...

Randomized Trial Finds DMARD Therapy for RA Has a Beneficial Effect on Vascular Inflammation, CV Risk

Dec 8th, 2022 - Use of a tumor necrosis factor inhibitor (TNFi) or triple therapy with conventional, synthetic disease-modifying antirheumatic drugs (DMARDs) for rheumatoid arthritis have similar beneficial effects in reducing patients' vascular inflammation and cardiovascular risk, according to results from a randomized, active comparator trial. Dr Daniel Solomon "The good news is, providers can rest assured ...

What It's Like as a Resident Taking the Night Watch

Dec 7th, 2022 - Every night when you wake up this week, it will be dark, and a brief wash of panic will tumble over you as your mind tries to rapidly sort out just how late you are to wherever it is you should be speeding towards on a Sunday at 9 PM. This is how most of my night shifts start. A black morning that my muddled resident brain spins its wheels through like a car stuck in mud with no traction. Most ...

Ask Knee OA Patients About Stair Climbing Difficulty

Dec 7th, 2022 - Asking knee osteoarthritis patients a simple question – do you have difficulty climbing stairs? – may predict the risk of future functional limitation, according to research presented at the annual meeting of the American College of Rheumatology. Finding out that the patient has difficulty also opens avenues for further evaluation and intervention, said Jason Jakiela, a PhD candidate at the Uni...

Diabetes Boosts Postoperative Opioid Use

Dec 6th, 2022 - Researchers published the study covered in this summary on Preprints With The Lancet as a preprint that has not yet been peer reviewed. Key Takeaways People with diabetes who underwent surgery had a significantly increased rate of prolonged opioid use (POU) compared to people without diabetes who underwent surgery in a retrospective, observational study of more than 43,000 people who had operat...

New Melting Hydrogel Bandage Could Treat Burn Wounds Faster, With Less Pain

Dec 5th, 2022 - A new type of wound dressing might change burn care for the better with one amazing property: dissolvability. Surgically debriding burn wounds can be tedious for doctors and excruciating for patients. To change that, bioengineers have created a new hydrogel formula that dissolves rapidly from wound sites, melting off in 6 minutes or less. "The removal of dressings, with the current standard of ...

Top Recent FDA Approvals
Clinical Advisor

Dec 1st, 2022 - The US Food and Drug Administration (FDA) approved several drugs relevant to conditions often treated by nurse practitioners and PAs. Approvals include treatments for hemophilia B, acute low back pain, postoperative nausea and vomiting, multiple myeloma, and fibromyalgia pain. Gene Therapy for Hemophilia B The first gene therapy for adults with hemophilia B (congential Factor IX deficiency) has...

Clinical Challenge: Vomiting and Testicle Pain
Clinical Advisor

Dec 1st, 2022 - History of Present Illness A patient in their mid-40s with a history of HIV presents to the emergency department (ED) with a 3- to 4-week history of vomiting and testicle pain that is associated with alternating constipation and diarrhea. The patient is currently not taking his HIV medication and reports decreased eating and drinking to help reduce vomiting. He has been using an over-the-counte...

Clinical Challenge: Vomiting and Testicle Pain
Clinical Advisor

Dec 1st, 2022 - Making the Diagnosis To accurately assess and diagnose this patient’s condition, the clinician needs to consider conditions that would cause testicle pain, vomiting, kidney disease, and dysuria yet have a normal testicular examination, normal urine assay, and normal scrotal ultrasonography imaging. It is important to always consider the worst-case scenario. In this case, referred pain from the ...

FDA OKs First Fecal Transplant Therapy for Recurrent C difficile

Dec 1st, 2022 - The US Food and Drug Administration (FDA) has approved the first fecal microbiota product to prevent recurrence of Clostridioides difficile infection (CDI) in people aged 18 years and older. Rebyota (fecal microbiota, live-jslm), from Ferring Pharmaceuticals, is intended for use after an individual has completed antibiotic treatment for recurrent CDI. It is not indicated for the first occurrenc...

Can Cannabis Help Patients With MS?

Dec 1st, 2022 - This transcript has been edited for clarity. Anne Cross, MD: Hello. I'm Anne Cross. Welcome to Medscape's InDiscussion series on multiple sclerosis. And today we're going to take on the somewhat controversial topic of the use of cannabis and cannabinoids in the treatment of symptoms in patients with multiple sclerosis. We have an expert to speak to us today about this, Dr Jacquelyn Bainbridge, ...