Jan 30th, 2023 - Although rare, acute hepatic porphyrias (AHPs) may be more common than previously thought, particularly among women between ages 15 and 50, according to a new clinical practice update from the American Gastroenterological Association. For acute attacks, treatment should include intravenous hemin, and for patients with recurrent attacks, a newly-approved therapy called givosiran should be consid.

Jan 30th, 2023 - An international group of physicians has issued consensus recommendations for the diagnosis and management of patients with early-onset colorectal cancer (eoCRC). Led by Giulia Martina Cavestro, MD, PhD, a gastroenterologist with the University Vita Salute San Raffaele Hospital, Milan, the Delphi Initiative for Early-Onset Colorectal Cancer group penned 31 recommendations for treating patients.

Jan 30th, 2023 - Supervised moderate and vigorous aerobic activity helped stave off type 2 diabetes in at-risk individuals with central obesity and nonalcoholic fatty liver disease, according to 10-year follow-up of a randomized trial from China. Compared with adults who did not exercise, the risk of diabetes was reduced by 49% in the vigorous exercise group (relative risk [RR] 0.51, 95% CI 0.27-0.94, P=0.01) a...

Jan 30th, 2023 - Higher protein doses did not improve critically ill patient outcomes, and may even be detrimental to patients with high organ failure and acute kidney injury, the EFFORT trial found. In nutritionally high-risk adults undergoing mechanical ventilation, alive hospital discharge for those who received higher doses of protein reached 46.1% by 60 days after randomization, compared with the 50.2% rat...

Jan 27th, 2023 - Steven R. Feldman, MD, PhD I suspect lebrikizumab is going to be another excellent atopic dermatitis (AD) treatment option.

Jan 27th, 2023 - As researchers continue to seek insights to improve the understanding, prevention, and treatment of Alzheimer disease and related dementias (ADRD), a growing body of research highlights significant racial and ethnic disparities in various aspects of these diseases.1 “In Blacks and Hispanics, the prevalence of ADRD is 1.5 to 2 times higher compared to non-Hispanic Whites,” said Timothy S. Chang,...

Jan 27th, 2023 - WINSTON-SALEM, N.C. – Jan. 27, 2023 – A good night’s sleep is crucial to health and well-being. Numerous research studies have shown that insomnia can increase the risk of cardiovascular events, obesity, diabetes and other illnesses. Now, a new study from researchers at Wake Forest University School of Medicine shows significant improvements in not only sleep quality, but also in improved auton...

Jan 27th, 2023 - Francis Crick Institute press release For immediate release Peer reviewed Experimental study / Modelling Animals Researchers at the Francis Crick Institute and King’s College London have created a tool to predict the effects of different diets on both cancerous cells and healthy cells. Their work could help disentangle the subtle metabolic changes associated with different types of nutrients, a...

Acute kidney injury is a sudden decrease in kidney function with or without kidney damage, occurring over a few hours or days. Diabetes, hypertension, and advanced age are primary risk factors for acute kidney injury. It is increasingly recognized as an in-hospital complication of sepsis, heart conditions, and surgery (1,2). Its most severe stage requires treatment with dialysis. Acute kidney i...

Each year, March is designated National Kidney Month to raise awareness about the prevention and early detection of kidney disease. In the United States, kidney diseases are the ninth leading cause of death (1). Among U.S. adults aged =20 years, 15% (30 million persons) are estimated to have chronic kidney disease. Chronic kidney disease is defined as damaged kidneys or a glomerular filtration ...

Currently 23 million U.S. adults have been diagnosed with diabetes (1). The two most common forms of diabetes are type 1 and type 2. Type 1 diabetes results from the autoimmune destruction of the pancreas's beta cells, which produce insulin. Persons with type 1 diabetes require insulin for survival; insulin may be given as a daily shot or continuously with an insulin pump (2). Type 2 diabetes i...

The American Dental Association has identified several barriers to adequate dental care, including appropriate case management, for vulnerable populations. The objective of this study was to examine the perceptions, attitudes, and beliefs of dental patients living with HIV/AIDS on the role and value of the dental case manager and the effect of its services on their oral or overall health.

Acute stress has been associated with diet and physical activity in some studies; however, the relationship between everyday stress and such behaviors is unclear. Researchers examine the associations between perceived stress, dietary behavior, physical activity, eating awareness, self-efficacy, and body mass index among healthy adults in the workplace.

Participant retention is a frequent concern in structured weight-management programs. Although research has explored participant characteristics influencing retention, little attention has been given to the influence of program characteristics. This study examined how program characteristics relate to participant retention in the Veterans Health Administration's weight-management program, MOVE!

Obesity, hypertension, and high cholesterol are risk factors for cardiovascular disease, which accounts for about 20% of deaths in Washington State. For most states, self-reports from the Behavioral Risk Factor Surveillance System provide the primary source of information on these risk factors. This study compares prevalence estimates of self-reported obesity, hypertension, and high cholesterol...

The Planet Health obesity prevention curriculum has prevented disordered weight control behavior (DWCB), including purging and abuse of diet pills, among middle-school girls in randomized trials, but the effects of the program on DWCB when implemented by schools under dissemination conditions are not known. Researchers attempted to determine the effects of the program by executing a 3-year obes...

Jan 26th, 2023 - Prescribing buprenorphine for opioid use disorder just got easier. The DATA-Waiver (X-Waiver) Program was eliminated on December 29, 2022, with President Biden’s of the Consolidated Appropriations Act of 2023, which contains the Mainstreaming Addiction Treatment Act (MAT Act). Now, practitioners with a current Drug Enforcement Administration (DEA) registration may prescribe buprenorphine for op...

Jan 26th, 2023 - Shared decision-making (SDM), a methodology for improving patient communication, education, and outcomes in preference-sensitive health care decisions, debuted in 1989 with the Ottawa Decision Support Framework1 and the creation of the Foundation for Informed Medical Decision Making (now the Informed Medical Decisions Foundation). 2 SDM enhances care by actively involving patients as partners in.

Jan 26th, 2023 - More than half of at-risk patients screened for diabetes at an urban emergency department (ED) were identified as having an abnormal HbA1c during a pilot program, researchers reported. The program was designed to flag the electronic health records (EHRs) of patients at risk for type 2 diabetes with a "best practice alert." During the 3-month study period, alerts were triggered for about 30% of ...

Jan 26th, 2023 - Soils are under pressure from current farming practices, and the challenges are only increasing with the growing demand for food production. Threats to soil health include loss of organic matter, loss of biodiversity, soil compaction from large machinery and, not least, loss of soil itself due to erosion. "We are at a crossroad; we need to do something if we are to preserve European and global ...