Oct 3rd, 2022 - HealthDay News — There is an association between vaccine-associated aluminum and persistent asthma among children with and without eczema, according to a study published online in Academic Pediatrics. Matthew F. Daley, MD, from Kaiser Permanente Colorado in Aurora, and colleagues conducted a retrospective cohort study in the Vaccine Safety Datalink to examine the association between cumulative ...

Oct 3rd, 2022 - Prenatal exposure to high-dose folic acid is associated with a greater than twofold increased risk for cancer in children of mothers with epilepsy, new data from a Scandinavian registry of more than 3 million pregnancies suggests. The increased risk for cancer did not change after considering other factors that could explain the risk, such as use of antiseizure medication (ASM). There was no in...

Oct 3rd, 2022 - The school setting is an important site of SARS-CoV-2 transmission, new data suggest. An analysis of surveillance data for almost 1000 exposures to SARS-CoV-2 found that students accounted for a higher proportion of infected individuals who caused onward transmission than did the public overall (46.2% vs 25%). “Our analysis suggests that younger age groups were deeply involved in the spread of ...

Sep 30th, 2022 - The oral Janus kinase (JAK) inhibitor baricitinib appears to improve symptoms of atopic dermatitis (AD) in children aged 2 years and up, as indicated by data from the phase 3 BREEZE-AD-PEDS trial. After 16 weeks of treatment, the primary endpoint ― an Investigators Global Assessment (IGA) score of 0 or 1 with at least a 2-point improvement from baseline ― was met by 41.7% of patients given 2 mg...

Sep 30th, 2022 - STOCKHOLM, Sweden — Enterovirus infection appears to be strongly linked to both type 1 diabetes and islet cell autoantibodies, new research suggests. The strength of the relationship, particularly within the first month of type 1 diabetes diagnosis, "further supports the rationale for development of enterovirus-targeted vaccines and antiviral therapy to prevent and reduce the impact of type 1 d...

Sep 29th, 2022 - Children with severe and nonsevere asthma are at risk for poor lung function trajectories into adulthood, with several clinically relevant factors predictive of changes in forced expiratory volume in 1 second (FEV1) over time, according study findings published in The Journal of Allergy and Clinical Immunology. The clinical predictors of lifelong poor lung function in children with asthma are n...

Sep 29th, 2022 - Young children and adolescent patients present differently with eosinophilic esophagitis (EoE), according to study results published in the Journal of Pediatric Gastroenterology and Nutrition. For the study, researchers sourced data from the European Pediatric Eosinophilic Esophagitis Registry (pEEr) registry, which was initiated in 2015 by the Eosinophilic Gastrointestinal Disorders Working Gr...

Sep 29th, 2022 - Pfizer and BioNTech have completed a submission to the Food and Drug Administration (FDA) requesting Emergency Use Authorization (EUA) for a 10-µg booster dose of the Omicron BA.4/BA.5-adapted bivalent COVID-19 vaccine for children 5 to 11 years of age. In August 2022, the FDA authorized the Pfizer-BioNTech COVID-19 Vaccine, Bivalent for use as a single booster dose in individuals 12 years of a...

Sep 29th, 2022 - WASHINGTON (Reuters) -U.S. President Joe Biden on Wednesday announced $8 billion in new private sector spending to fight hunger, including hundreds of millions of dollars for meals, after lawmakers failed to further extend pandemic-era nutrition supports like universal school meals and increased aid to food banks. The pledges were announced as part of a White House summit on Hunger, Nutrition a...

Sep 29th, 2022 - Editor's note: Find the latest long COVID news and guidance in Medscape's Long COVID Resource Center. Working with physicians from multiple specialties, the American Academy of Physical Medicine and Rehabilitation (AAPM&R) has issued the first set of guidelines related to the diagnosis and treatment of pediatric patients with long COVID. The physiatrist organization also issued separate guidanc...

Sep 28th, 2022 - Who would have thought we would need to refresh our knowledge on polio virus in 2022? Fate seems cruel to add this concern on the heels of SARS-CoV-2, monkeypox, abnormal seasons for RSV, acute flaccid myelitis (AFM) linked to enteroviruses, and a summer of parechovirus causing infant meningitis. But confirmation that indeed an adult had polio with paralytic disease raises concerns among public...

Sep 28th, 2022 - LAGOS (Reuters) - Nigeria faces worsening malnutrition in the northwest due to insecurity, high food prices and the impact of climate change, Medicines Sans Frontiers (MSF) said on Tuesday, calling for the region to be included in United Nations funding plans next year. Gunmen have terrorised the northwest, killing and kidnapping people for ransom this year. Africa's most populous nation is alr...

Sep 28th, 2022 - It might be possible to develop a simple test to identify newborn children who are at risk of later developing atopic dermatitis (AD), according to findings from a Danish prospective birth cohort study. In the study, the Barrier Dysfunction in Atopic Newborns Study (BABY), several biomarkers were found in the skin cells of newborns that were predictive not only for having AD but also for having...

Sep 28th, 2022 - The COVID-19 pandemic has been associated with the development of anorexia nervosa in Canadian children and adolescents, data suggest. Preliminary results of the Canadian Paediatric Surveillance Program (CPSP) indicate that the pandemic has been a precipitating factor in the development of anorexia nervosa in almost half of children and adolescents studied. The pandemic also has precipitated ho...

Sep 28th, 2022 - Almost everything about the opening of the 2019 Prosper High School Eagles' football season was big. The game in this Dallas-Fort Worth suburb began with fireworks and a four-airplane flyover. A trained eagle soared over the field. And some 12,000 fans filled the team's new stadium, a $53 million colossus with the largest video screen of any high school venue in Texas. Atop the stadium was also...

Sep 27th, 2022 - Treatment-specific and shared predictors for response to pharmacotherapies for attention-deficit/hyperactivity disorder (ADHD) among children were found in a study published in the Journal of the American Academy of Child & Adolescent Psychiatry. Children (N=181) with ADHD aged 7 to 14 years were recruited to participate in this trial conducted by the University of California, Los Angeles. Pret...

Sep 27th, 2022 - The effect of sexual dimorphisms on the immune phenotype of both healthy individuals and those with autoimmunity were assessed in a study published in The Lancet Rheumatology. According to the study authors, the current study is the first to report on the immune-cell phenotype by comparing sex and gender differences among young postpubertal cisgender men and cisgender women, both with and witho...

Sep 27th, 2022 - Editor's note: Find the latest COVID-19 news and guidance in Medscape's Coronavirus Resource Center. STOCKHOLM, Sweden — It remains inconclusive whether SARS-CoV-2 infection predisposes children and adolescents to a higher risk of type 1 diabetes. Data from two new studies presented last week, and a research letter just published, add to the growing body of knowledge on the subject, but still c...

Sep 27th, 2022 - Allergic trajectories occur in clusters, are affected by early life, genetics, and clinical traits, and don't change much after 18 years of age, a new study from Europe reports. "Seven robust allergic clusters were identified and showed associations with early life and genetic factors as well as clinical characteristics," lead study author Anna Kilanowski, MSc, of the German Research Center for...

Sep 27th, 2022 - I watched you in the garage, with your wipes and your mask, your gloves and bottles of sprays and potions. I admired your fealty to CNN's Dr Sanjay Gupta as he demonstrated the proper technique for disinfecting groceries. I watched sterile protocol being broken and quietly closed the garage door. Dr Alison Heru I listened to your descriptions of the agility of the virus with each exhalation of ...