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About 8,248 results

To Get Pregnant Smokers to Quit, Money Talks
https://www.medpagetoday.com/primarycare/smoking/95977

Dec 2nd, 2021 - Cold cash proved to be an effective incentive for pregnant French women to stop smoking during gestation, a randomized trial indicated. Quit rates were doubled in a group rewarded with money for confirmed abstinence, relative to a control group that received payments for showing up to clinic visits but not for actual smoking cessation (16% vs 7%; OR 2.45, 95% CI 1.34-4.49), reported Ivan Berlin...

Patient Risk, Not Disease Duration, Key to Timing Biologics in IBD
https://www.medscape.com/viewarticle/963195

Nov 17th, 2021 - The decision to Initiate biologics early in the treatment of Crohn's disease (CD) and ulcerative colitis (UC) should be based on complication risk, not on the assumption that earlier treatment produces better results, new research suggests. Results of a meta-analysis of randomized controlled trials show that "the proportional biologic/placebo treatment effect on remission and response to biolog...

One Quarter of Lung Cancer Patients Alive at 5 Years
https://www.medscape.com/viewarticle/963046

Nov 16th, 2021 - In recent years, the survival rate for patients with lung cancer has increased to the point where now, almost one quarter of patients with lung cancer are alive 5 years after being diagnosed. This new statistic is highlighted in the State of Lung Cancer report from the American Lung Association (ALA), published online on November 16. "If you look back, the 5-year survival rate has been very slo...

COVID-19 Hot Spots Offer Sign of What Could Be Ahead for US
https://www.medscape.com/viewarticle/962842

Nov 12th, 2021 - Editor's note: Find the latest COVID-19 news and guidance in Medscape's Coronavirus Resource Center. The contagious delta variant is driving up COVID-19 hospitalizations in the Mountain West and fueling disruptive outbreaks in the North, a worrisome sign of what could be ahead this winter in the U.S. While trends are improving in Florida, Texas and other Southern states that bore the worst of t...

Sleep-Disordered Breathing Could Inflate Risk for Severe COVID-19
https://www.medscape.com/viewarticle/962876

Nov 12th, 2021 - Find the latest COVID-19 news and guidance in Medscape's  Coronavirus Resource Center. People with sleep-disordered breathing or sleep-related hypoxia — low oxygen levels during sleeping — are no more likely than other adults to get infected with SARS-CoV-2 and develop COVID-19. However, if infected, they are at a 31% higher risk of getting hospitalized or dying from the illness, new research r...

At 5 Years, iFR Found as Effective and Safe as FFR for Guiding PCI Intervention
https://www.medscape.com/viewarticle/962723

Nov 11th, 2021 - The rate of major adverse cardiac events (MACE) over 5 years is similar whether revascularization is guided by instantaneous wave-free ratio (iFR) or fractional flow reserve (FFR), according to long-term results of the iFR-SWEDEHEART study. "The results are about the same as reported at 12 months. There were no significant differences in any outcome we evaluated," according to Matthias Götberg,...

Insomnia Linked to Higher Risk for Aneurysm, SAH
https://www.medscape.com/viewarticle/962729

Nov 11th, 2021 - Researchers are reporting a novel association between insomnia and both intracranial aneurysm and aneurysmal subarachnoid hemorrhage (aSAH). The investigators used a Mendelian randomization to investigate whether modifiable lifestyle and cardiometabolic risk factors affected the prevalence of ruptured or unruptured intracranial aneurysm (IA) and aSAH. In addition to common risk factors such as ...

Association Between Epilepsy and Mortality Risk
https://www.medscape.com/viewarticle/962361

Nov 5th, 2021 - Takeaway A study found that the risk of mortality was higher in people with epilepsy (PWE). Emergency department attendance and admissions, anti-epileptic drug (AED) polytherapy, status epilepticus, depression and injuries were risk factors associated with an increased risk of mortality. Why this matters Findings warrant future studies to identify PWE at high risk and treat them with clinical i...

Decades Spent Searching for Genes Linked to Rare Blood Cancer
https://www.medscape.com/viewarticle/962308

Nov 4th, 2021 - Mary Lou McMaster, MD, has spent her entire career at the National Cancer Institute (NCI) searching for the genetic underpinnings that give rise to Waldenstrom's macroglobulinemia (WM). After searching for decades, she has yet to uncover a "smoking gun," though a few tantalizing clues have emerged along the way. "Our questions are pretty basic: Why are some people more susceptible to developing...

England Could Be First to Allow e-Cigarettes on Prescription
https://www.medscape.com/viewarticle/961849

Oct 29th, 2021 - Vaping is already promoted as being a safer alternative to tobacco cigarettes, but the Medicines and Healthcare products Regulatory Agency (MHRA) is now considering licensing the devices for use in smoking cessation. That could mean England becomes the first country in the world to prescribe e-cigs to help reduce smoking rates, if devices are supported for NHS funding by the National Institute ...

Lung Cancer Screening for Head and Neck Survivors?
https://www.medpagetoday.com/radiology/diagnosticradiology/95321

Oct 28th, 2021 - Head and neck cancer survivors are at an especially high risk for second primary lung cancers, a secondary analysis of the National Lung Screening Trial (NLST) suggested. After adjustment for various factors including pack-years of smoking, lung cancer incidence among NLST participants with a history of head and neck cancer was more than doubled compared to those without such a history, at 2,08...

A Veteran With Lesions, Alcohol Use, and Opioid Dependence
https://www.medscape.com/viewarticle/961405

Oct 27th, 2021 - Editor's Note: The Case Challenge series includes difficult-to-diagnose conditions, some of which are not frequently encountered by most clinicians but are nonetheless important to accurately recognize. Test your diagnostic and treatment skills using the following patient scenario and corresponding questions. If you have a case that you would like to suggest for a future Case Challenge, please ...

40 Million in U.S. Had a Substance Use Disorder in 2020, SAMHSA Survey Finds
https://www.medpagetoday.com/psychiatry/addictions/95249

Oct 25th, 2021 - WASHINGTON -- More than 40 million Americans were living with a substance use disorder in 2020, Capt. Michael King, PhD, MSW, of the Substance Abuse and Mental Health Services Administration (SAMHSA) said Monday. King was reporting on the results of the SAMHSA annual National Survey on Drug Use and Health for 2020. "Many longstanding behavioral health problems are still here and are possibly ge...

e-Cigarettes No Guarantee Against Relapse for Smokers
https://www.medscape.com/viewarticle/961495

Oct 25th, 2021 - Former smokers who use e-cigarettes are just as likely to light back up, compared to those using other nicotine alternatives, new evidence reveals. A recent study showed that people who quit cigarette smoking and then started using electronic cigarettes were just as likely to return to traditional tobacco cigarettes as people who switched to nicotine gum and other products. Quitting tobacco com...

Maternal Smoking and the Risk of Gallbladder Disease and Gallstones in Adult Offspring
https://www.medscape.com/viewarticle/961566

Oct 25th, 2021 - Takeaway Exposure to maternal smoking was associated with a higher risk of incident gallbladder disease/gallstone events in the adult offspring. This association was more pronounced in women and populations with low body mass index. Why this matters Findings underscore the importance of smoking cessation during pregnancy in preventing adulthood chronic diseases in offspring. Study design The st...

Smoking a 'Major Driver' of Worse Outcomes After Traumatic Brain Injury
https://www.medscape.com/viewarticle/961231

Oct 20th, 2021 - Vascular risk factors, smoking in particular, are associated with worse outcomes following traumatic brain injury (TBI), new research shows. Dr Andrea Schneider "The big takeaway here is that smoking appears to be a really big driver of adverse outcomes after TBI," study investigator Andrea Schneider, MD, PhD, assistant professor of neurology, University of Pennsylvania Division of Neurocritica...

Combined Treatments Most Effective for Smoking Cessation, Study Finds
https://www.medscape.com/viewarticle/961033

Oct 18th, 2021 - Combination treatment, particularly varenicline and nicotine replacement therapy (NRT), are the most effective tobacco cessation pharmacotherapies, according to the findings of the largest review to examine the effectiveness and safety of e-cigarettes and pharmacological interventions for smoking cessation. The study, led by the University of Bristol, included systematic reviews and Bayesian ne...

Case Report: Lung Cancer Shrinks in Patient Using CBD Oil
https://www.medscape.com/viewarticle/960949

Oct 15th, 2021 - A case report describes the dramatic shrinkage of a tumor to a quarter of its original size in a patient with non–small cell lung cancer (NSCLC) who had declined conventional treatment, continued smoking, and who later revealed that she was ingesting cannabidiol (CBD) oil. The patient was an 80-year-old woman. At diagnosis, the tumor measured 41 mm, and there was no evidence of local or further...

US FDA Gives Marketing Nod to an e-Cigarette for the First Time
https://www.medscape.com/viewarticle/960766

Oct 13th, 2021 - (Reuters) - The U.S. Food and Drug Administration (FDA) on Tuesday allowed British American Tobacco Plc (BAT) to market its Vuse Solo e-cigarettes and tobacco-flavored pods, making it the first-ever vapor product to get clearance from the health regulator. The FDA said the approval came after analysis of data from the manufacturer that showed that using Vuse's tobacco-flavored products could he...

Polygenic Risk Score a New Tool for Predicting Late-Onset Alzheimer's?
https://www.medscape.com/viewarticle/960529

Oct 8th, 2021 - A higher polygenic risk (PGR) score may predict late-onset Alzheimer's disease (LOAD), new research shows. Investigators found a higher PGR was significantly linked to smaller hippocampal volume and poorer executive function in physically and cognitively healthy adults. Rachana Tank "Our study is a small, but hopefully robust, step forward," study investigator Rachana Tank, a PhD candidate and ...